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Manuel A. Ortega - Publications

Affiliations: 
Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
Biochemistry
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8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Bollenbach M, Ortega M, Orman M, Drennan CL, Balskus EP. Discovery of a Cyclic Choline Analog That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria. Acs Medicinal Chemistry Letters. 11: 1980-1985. PMID 33062182 DOI: 10.1021/Acsmedchemlett.0C00005  0.547
2019 Petronikolou N, Ortega MA, Borisova SA, Nair SK, Metcalf WW. Molecular basis of Bacillus subtilis ATCC6633 self-resistance to the phosphono-oligopeptide antibiotic rhizocticin. Acs Chemical Biology. PMID 30830751 DOI: 10.1021/Acschembio.9B00030  0.623
2016 Ortega MA, Cogan DP, Mukherjee S, Garg N, Li B, Thibodeaux GN, Maffioli S, Donadio S, Sosio M, Escano J, Smith L, Nair SK, van der Donk WA. Two flavoenzymes catalyze the post-translational generation of 5-chlorotryptophan and 2-aminovinyl-cysteine during NAI-107 biosynthesis. Acs Chemical Biology. PMID 28032983 DOI: 10.1021/Acschembio.6B01031  0.7
2016 Ortega MA, van der Donk WA. New Insights into the Biosynthetic Logic of Ribosomally Synthesized and Post-translationally Modified Peptide Natural Products. Cell Chemical Biology. 23: 31-44. PMID 26933734 DOI: 10.1016/J.Chembiol.2015.11.012  0.618
2016 Ortega MA, Hao Y, Walker MC, Donadio S, Sosio M, Nair SK, van der Donk WA. Structure and tRNA Specificity of MibB, a Lantibiotic Dehydratase from Actinobacteria Involved in NAI-107 Biosynthesis. Cell Chemical Biology. PMID 26877024 DOI: 10.1016/J.Chembiol.2015.11.017  0.666
2015 Ortega MA, Hao Y, Zhang Q, Walker MC, van der Donk WA, Nair SK. Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB. Nature. 517: 509-12. PMID 25363770 DOI: 10.1038/Nature13888  0.69
2014 Zhang Q, Ortega M, Shi Y, Wang H, Melby JO, Tang W, Mitchell DA, van der Donk WA. Structural investigation of ribosomally synthesized natural products by hypothetical structure enumeration and evaluation using tandem MS. Proceedings of the National Academy of Sciences of the United States of America. 111: 12031-6. PMID 25092299 DOI: 10.1073/Pnas.1406418111  0.643
2014 Ortega MA, Velásquez JE, Garg N, Zhang Q, Joyce RE, Nair SK, van der Donk WA. Substrate specificity of the lanthipeptide peptidase ElxP and the oxidoreductase ElxO. Acs Chemical Biology. 9: 1718-25. PMID 24866416 DOI: 10.1021/Cb5002526  0.659
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