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Derek A. Pratt, Ph.D. - Publications

Affiliations: 
2003-2005 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
 2010- Chemistry University of Ottawa, Ottawa, ON, Canada 
Area:
Free radicals, antioxidants
Website:
http://dpra24.wix.com/theprattgroup#!derek/c41f
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123 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wu Z, Vlaming R, Donohoe M, Pratt DA. Interrupted Homolytic Substitution Enables Organoboron Compounds to Inhibit Radical Chain Reactions Rather than Initiate Them. Journal of the American Chemical Society. PMID 38156607 DOI: 10.1021/jacs.3c12438  0.393
2023 Saraev DD, Wu Z, Kim HH, Porter NA, Pratt DA. Intramolecular H-Atom Transfers in Alkoxyl Radical Intermediates Underlie the Apparent Oxidation of Lipid Hydroperoxides by Fe(II). Acs Chemical Biology. PMID 37639355 DOI: 10.1021/acschembio.3c00412  0.522
2023 Roldan BJ, Hammerstad TA, Galliher MS, Keylor MH, Pratt DA, Stephenson CRJ. Leveraging the Persistent Radical Effect in the Synthesis of trans-2,3-Diaryl-Dihydrobenzofurans. Angewandte Chemie (International Ed. in English). e202305801. PMID 37390358 DOI: 10.1002/anie.202305801  0.321
2023 Wu Z, Barayeu U, Schilling D, Dick TP, Pratt DA. Emergence of (hydro)persulfides as suppressors of lipid peroxidation and ferroptotic cell death. Current Opinion in Chemical Biology. 76: 102353. PMID 37356334 DOI: 10.1016/j.cbpa.2023.102353  0.341
2023 Wu Z, Pratt DA. Radical approaches to C-S bonds. Nature Reviews. Chemistry. PMID 37344618 DOI: 10.1038/s41570-023-00505-x  0.301
2022 Wu Z, Khodade VS, Chauvin JR, Rodriguez D, Toscano JP, Pratt DA. Hydropersulfides Inhibit Lipid Peroxidation and Protect Cells from Ferroptosis. Journal of the American Chemical Society. PMID 35977425 DOI: 10.1021/jacs.2c06804  0.356
2021 Zilka O, Poon JF, Pratt DA. Radical-Trapping Antioxidant Activity of Copper and Nickel Bis(Thiosemicarbazone) Complexes Underlies Their Potency as Inhibitors of Ferroptotic Cell Death. Journal of the American Chemical Society. 143: 19043-19057. PMID 34730342 DOI: 10.1021/jacs.1c08254  0.359
2021 Wu Z, Pratt DA. A Divergent Strategy for Site-Selective Radical Disulfuration of Carboxylic Acids with Trisulfide-1,1-Dioxides. Angewandte Chemie (International Ed. in English). PMID 33929774 DOI: 10.1002/anie.202104595  0.335
2021 Shah R, Poon JF, Haidasz EA, Pratt DA. Temperature-Dependent Effects of Alkyl Substitution on Diarylamine Antioxidant Reactivity. The Journal of Organic Chemistry. PMID 33900079 DOI: 10.1021/acs.joc.1c00365  0.349
2020 Porter NA, Xu L, Pratt DA. Reactive Sterol Electrophiles: Mechanisms of Formation and Reactions with Proteins and Amino Acid Nucleophiles. Chemistry (Basel, Switzerland). 2: 390-417. PMID 35372835 DOI: 10.3390/chemistry2020025  0.531
2020 Raycroft MAR, Chauvin JR, Galliher MS, Romero KJ, Stephenson CRJ, Pratt DA. Quinone methide dimers lacking labile hydrogen atoms are surprisingly excellent radical-trapping antioxidants. Chemical Science. 11: 5676-5689. PMID 32832049 DOI: 10.1039/D0Sc02020F  0.486
2020 Soula M, Weber RA, Zilka O, Alwaseem H, La K, Yen F, Molina H, Garcia-Bermudez J, Pratt DA, Birsoy K. Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers. Nature Chemical Biology. PMID 32778843 DOI: 10.1038/S41589-020-0613-Y  0.333
2020 Poon JF, Zilka O, Pratt DA. Potent Ferroptosis Inhibitors Can Catalyze the Cross-Dismutation of Phospholipid-Derived Peroxyl Radicals and Hydroperoxyl Radicals. Journal of the American Chemical Society. PMID 32698570 DOI: 10.1021/Jacs.0C06379  0.455
2020 Wu Z, Pratt DA. Radical Substitution Provides a Unique Route to Disulfides. Journal of the American Chemical Society. PMID 32427472 DOI: 10.1021/Jacs.0C03626  0.473
2020 Romero KJ, Keylor MH, Griesser M, Zhu X, Strobel EJ, Pratt DA, Stephenson CRJ. Synthesis of vitisin A & D enabled by a persistent radical equilibrium. Journal of the American Chemical Society. PMID 32156107 DOI: 10.1021/Jacs.0C01714  0.613
2020 Lübbesmeyer M, Mackay EG, Raycroft MAR, Elfert J, Pratt DA, Studer A. Base-promoted C-C bond activation enables radical allylation with homoallylic alcohols. Journal of the American Chemical Society. PMID 31941267 DOI: 10.1021/Jacs.9B12343  0.393
2020 Porter NA, Xu L, Pratt DA. Reactive Sterol Electrophiles: Mechanisms of Formation and Reactions with Proteins and Amino Acid Nucleophiles Chemistry. 2: 390-417. DOI: 10.3390/Chemistry2020025  0.584
2020 Raycroft MAR, Chauvin JR, Galliher MS, Romero KJ, Stephenson CRJ, Pratt DA. Quinone methide dimers lacking labile hydrogen atoms are surprisingly excellent radical-trapping antioxidants Chemical Science. 11: 5676-5689. DOI: 10.1039/d0sc02020f  0.33
2020 Garrett GE, Pratt DA, Parent JS. Hydrogen Atom Abstraction from Polyolefins: Experimental and Computational Studies of Model Systems Macromolecules. 53: 2793-2800. DOI: 10.1021/Acs.Macromol.9B02091  0.345
2019 Schaefer EL, Zopyrus N, Zielinski ZAM, Facey GA, Pratt DA. On the Products of Cholesterol Autoxidation in Phospholipid Bilayers and the Formation of Secosterols Derived Therefrom. Angewandte Chemie (International Ed. in English). PMID 31793116 DOI: 10.1002/Anie.201914637  0.329
2019 Conrad M, Pratt DA. The chemical basis of ferroptosis. Nature Chemical Biology. 15: 1137-1147. PMID 31740834 DOI: 10.1038/S41589-019-0408-1  0.325
2019 Doll S, Freitas FP, Shah R, Aldrovandi M, da Silva MC, Ingold I, Grocin AG, Xavier da Silva TN, Panzilius E, Scheel C, Mourão A, Buday K, Sato M, Wanninger J, Vignane T, ... ... Pratt D, et al. FSP1 is a glutathione-independent ferroptosis suppressor. Nature. PMID 31634899 DOI: 10.1038/S41586-019-1707-0  0.358
2019 Shah R, Farmer LA, Zilka O, Van Kessel ATM, Pratt DA. Beyond DPPH: Use of Fluorescence-Enabled Inhibited Autoxidation to Predict Oxidative Cell Death Rescue. Cell Chemical Biology. PMID 31564533 DOI: 10.1016/J.Chembiol.2019.09.007  0.421
2019 Chauvin JR, Griesser M, Pratt DA. The antioxidant activity of polysulfides: it's radical! Chemical Science. 10: 4999-5010. PMID 31183049 DOI: 10.1039/C9Sc00276F  0.642
2019 Firsov AM, Fomich MA, Bekish AV, Sharko OL, Kotova EA, Saal HJ, Vidovic D, Shmanai VV, Pratt DA, Antonenko YN, Shchepinov MS. Threshold Protective Effect of Deuterated Polyunsaturated Fatty Acids on Peroxidation of Lipid Bilayers. The Febs Journal. PMID 30851224 DOI: 10.1111/Febs.14807  0.359
2019 Zielinski ZAM, Pratt DA. H-Atom Abstraction vs. Addition: Accounting for the Diverse Product Distribution in the Autoxidation of Cholesterol & its Esters. Journal of the American Chemical Society. PMID 30624910 DOI: 10.1021/Jacs.8B11524  0.356
2018 Romero KJ, Galliher MS, Raycroft MAR, Chauvin JR, Bosque I, Pratt DA, Stephenson CRJ. Electrochemical Dimerization of Phenylpropenoids and the Surprising Antioxidant Activity of the Resultant Quinone Methide Dimers. Angewandte Chemie (International Ed. in English). 57: 17125-17129. PMID 30474921 DOI: 10.1002/Anie.201810870  0.428
2018 Griesser M, Chauvin JR, Pratt DA. The hydrogen atom transfer reactivity of sulfinic acids. Chemical Science. 9: 7218-7229. PMID 30288241 DOI: 10.1039/C8Sc02400F  0.659
2018 Romero KJ, Galliher MS, Pratt DA, Stephenson CRJ. Radicals in natural product synthesis. Chemical Society Reviews. PMID 30101272 DOI: 10.1039/C8Cs00379C  0.434
2018 Harrison KA, Haidasz EA, Griesser M, Pratt DA. Inhibition of hydrocarbon autoxidation by nitroxide-catalyzed cross-dismutation of hydroperoxyl and alkylperoxyl radicals. Chemical Science. 9: 6068-6079. PMID 30079220 DOI: 10.1039/C8Sc01575A  0.682
2018 Poon JF, Pratt DA. Recent Insights on Hydrogen Atom Transfer in the Inhibition of Hydrocarbon Autoxidation. Accounts of Chemical Research. PMID 30035527 DOI: 10.1021/Acs.Accounts.8B00251  0.529
2018 Shah R, Shchepinov MS, Pratt DA. Resolving the Role of Lipoxygenases in the Initiation and Execution of Ferroptosis. Acs Central Science. 4: 387-396. PMID 29632885 DOI: 10.1021/Acscentsci.7B00589  0.376
2018 Griesser M, Shah R, Van Kessel AT, Zilka O, Haidasz EA, Pratt DA. The Catalytic Reaction of Nitroxides with Peroxyl Radicals and its Relevance to their Cytoprotective Properties. Journal of the American Chemical Society. PMID 29451786 DOI: 10.1021/Jacs.8B00998  0.67
2017 Farmer LA, Haidasz EA, Griesser M, Pratt DA. Phenoxazine: A Privileged Scaffold for Radical-Trapping Antioxidants. The Journal of Organic Chemistry. PMID 28885854 DOI: 10.1021/Acs.Joc.7B02025  0.665
2017 Shah R, Margison K, Pratt DA. The Potency of Diarylamine Radical-Trapping Antioxidants as Inhibitors of Ferroptosis Underscores the Role of Autoxidation in the Mechanism of Cell Death. Acs Chemical Biology. PMID 28837769 DOI: 10.1021/Acschembio.7B00730  0.401
2017 Chauvin JR, Griesser M, Pratt DA. Hydropersulfides: H-Atom Transfer Agents par Excellence. Journal of the American Chemical Society. PMID 28419803 DOI: 10.1021/Jacs.7B02571  0.654
2017 Zilka O, Shah R, Li B, Friedmann Angeli JP, Griesser M, Conrad M, Pratt DA. On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death. Acs Central Science. 3: 232-243. PMID 28386601 DOI: 10.1021/Acscentsci.7B00028  0.641
2017 Angeli JP, Shah R, Pratt DA, Conrad M. Ferroptosis Inhibition: Mechanisms and Opportunities. Trends in Pharmacological Sciences. PMID 28363764 DOI: 10.1016/J.Tips.2017.02.005  0.304
2017 Haidasz EA, Pratt DA. Diazaphenoxazines and Diazaphenothiazines: Synthesis of the "Correct" Isomers Reveals They Are Highly Reactive Radical-Trapping Antioxidants. Organic Letters. PMID 28350453 DOI: 10.1021/Acs.Orglett.7B00615  0.441
2017 Zheng L, Griesser M, Pratt DA, Greenberg MM. Aminyl Radical Generation via Tandem Norrish Type I Photocleavage, β-Fragmentation: Independent Generation and Reactivity of the 2'-Deoxyadenosin- N6-yl Radical. The Journal of Organic Chemistry. PMID 28318253 DOI: 10.1021/Acs.Joc.7B00093  0.648
2017 Zielinski ZA, Pratt DA. Lipid Peroxidation: Kinetics, Mechanisms & Products. The Journal of Organic Chemistry. PMID 28248497 DOI: 10.1021/Acs.Joc.7B00152  0.338
2016 Chauvin JR, Haidasz EA, Griesser M, Pratt DA. Polysulfide-1-oxides react with peroxyl radicals as quickly as hindered phenolic antioxidants and do so by a surprising concerted homolytic substitution. Chemical Science. 7: 6347-6356. PMID 28567247 DOI: 10.1039/C6Sc01434H  0.667
2016 Keylor MH, Matsuura BS, Griesser M, Chauvin JR, Harding RA, Kirillova MS, Zhu X, Fischer OJ, Pratt DA, Stephenson CR. Synthesis of resveratrol tetramers via a stereoconvergent radical equilibrium. Science (New York, N.Y.). 354: 1260-1265. PMID 27940867 DOI: 10.1126/Science.Aaj1597  0.64
2016 Chauvin JR, Pratt DA. On the Reactions of Thiols, Sulfenic Acids, and Sulfinic Acids with Hydrogen Peroxide. Angewandte Chemie (International Ed. in English). PMID 27933690 DOI: 10.1002/Anie.201610402  0.403
2016 Shah R, Pratt DA. Determination of Key Hydrocarbon Autoxidation Products By Fluorescence. The Journal of Organic Chemistry. PMID 27384266 DOI: 10.1021/Acs.Joc.6B01032  0.359
2016 Zielinski ZA, Pratt DA. Cholesterol Autoxidation Revisited: Debunking the Dogma Associated with the Most Vilified of Lipids. Journal of the American Chemical Society. PMID 27210001 DOI: 10.1021/Jacs.6B03344  0.398
2016 Haidasz EA, Meng D, Amorati R, Baschieri A, Ingold KU, Valgimigli L, Pratt DA. Acid is Key to the Radical-Trapping Antioxidant Activity of Nitroxides. Journal of the American Chemical Society. PMID 27023326 DOI: 10.1021/Jacs.6B00677  0.605
2015 Li B, Zheng F, Chauvin JR, Pratt DA. The medicinal thiosulfinates from garlic and are not radical-trapping antioxidants in liposomes and cells, but lipophilic analogs are. Chemical Science. 6: 6165-6178. PMID 30090232 DOI: 10.1039/C5Sc02270C  0.495
2015 Haidasz EA, van Kessel AT, Pratt DA. A Continuous Spectrophotometric Approach to Accurately Determine the Reactivity of Radical-Trapping Antioxidants. The Journal of Organic Chemistry. PMID 26529543 DOI: 10.1021/Acs.Joc.5B02183  0.456
2015 Valgimigli L, Pratt DA. Maximizing the reactivity of phenolic and aminic radical-trapping antioxidants: just add nitrogen! Accounts of Chemical Research. 48: 966-75. PMID 25839082 DOI: 10.1021/Acs.Accounts.5B00035  0.502
2015 Shah R, Haidasz EA, Valgimigli L, Pratt DA. Unprecedented inhibition of hydrocarbon autoxidation by diarylamine radical-trapping antioxidants. Journal of the American Chemical Society. 137: 2440-3. PMID 25668303 DOI: 10.1021/Ja5124144  0.398
2015 Li B, Pratt DA. Methods for determining the efficacy of radical-trapping antioxidants. Free Radical Biology & Medicine. 82: 187-202. PMID 25660993 DOI: 10.1016/J.Freeradbiomed.2015.01.020  0.502
2015 Matsuura BS, Keylor MH, Li B, Lin Y, Allison S, Pratt DA, Stephenson CR. A scalable biomimetic synthesis of resveratrol dimers and systematic evaluation of their antioxidant activities. Angewandte Chemie (International Ed. in English). 54: 3754-7. PMID 25650836 DOI: 10.1002/Anie.201409773  0.451
2015 Chauvin JPR, Zielinski ZAM, Pratt DA. Inspired by garlic: insights on the chemistry of sulfenic acids and the radical-trapping antioxidant activity of organosulfur compounds Canadian Journal of Chemistry. 94: 1-8. DOI: 10.1139/Cjc-2015-0438  0.368
2014 Haidasz EA, Shah R, Pratt DA. The catalytic mechanism of diarylamine radical-trapping antioxidants. Journal of the American Chemical Society. 136: 16643-50. PMID 25354493 DOI: 10.1021/Ja509391U  0.44
2014 Ingold KU, Pratt DA. Advances in radical-trapping antioxidant chemistry in the 21st century: a kinetics and mechanisms perspective. Chemical Reviews. 114: 9022-46. PMID 25180889 DOI: 10.1021/Cr500226N  0.545
2014 Zielinski Z, Presseau N, Amorati R, Valgimigli L, Pratt DA. Redox chemistry of selenenic acids and the insight it brings on transition state geometry in the reactions of peroxyl radicals. Journal of the American Chemical Society. 136: 1570-8. PMID 24383573 DOI: 10.1021/Ja411493T  0.463
2014 Garrett GE, Mueller E, Pratt DA, Parent JS. Reactivity of polyolefins toward cumyloxy radical: Yields and regioselectivity of hydrogen atom transfer Macromolecules. 47: 544-551. DOI: 10.1021/Ma402177V  0.396
2013 Valgimigli L, Bartolomei D, Amorati R, Haidasz E, Hanthorn JJ, Nara SJ, Brinkhorst J, Pratt DA. 3-Pyridinols and 5-pyrimidinols: Tailor-made for use in synergistic radical-trapping co-antioxidant systems. Beilstein Journal of Organic Chemistry. 9: 2781-92. PMID 24367442 DOI: 10.3762/Bjoc.9.313  0.469
2013 Zheng F, Pratt DA. Antioxidant generation and regeneration in lipid bilayers: the amazing case of lipophilic thiosulfinates and hydrophilic thiols. Chemical Communications (Cambridge, England). 49: 8181-3. PMID 23938951 DOI: 10.1039/C3Cc44401E  0.45
2013 Li B, Harjani JR, Cormier NS, Madarati H, Atkinson J, Cosa G, Pratt DA. Besting vitamin E: sidechain substitution is key to the reactivity of naphthyridinol antioxidants in lipid bilayers. Journal of the American Chemical Society. 135: 1394-405. PMID 23276254 DOI: 10.1021/Ja309153X  0.503
2013 Haidasz EA, Li B, Pratt DA. Reaction mechanisms: Radical and radical ion reactions Annual Reports On the Progress of Chemistry - Section B. 109: 295-327. DOI: 10.1039/C3Oc90013D  0.393
2012 Hanthorn JJ, Haidasz E, Gebhardt P, Pratt DA. A versatile fluorescence approach to kinetic studies of hydrocarbon autoxidations and their inhibition by radical-trapping antioxidants. Chemical Communications (Cambridge, England). 48: 10141-3. PMID 22952050 DOI: 10.1039/C2Cc35214A  0.369
2012 Huang M, Garrett GE, Birlirakis N, Bohé L, Pratt DA, Crich D. Dissecting the mechanisms of a class of chemical glycosylation using primary 13C kinetic isotope effects Nature Chemistry. 4: 663-667. PMID 22824899 DOI: 10.1038/Nchem.1404  0.337
2012 Hanthorn JJ, Valgimigli L, Pratt DA. Preparation of highly reactive pyridine- and pyrimidine-containing diarylamine antioxidants. The Journal of Organic Chemistry. 77: 6908-16. PMID 22788575 DOI: 10.1021/Jo301013C  0.403
2012 Hanthorn JJ, Amorati R, Valgimigli L, Pratt DA. The reactivity of air-stable pyridine- and pyrimidine-containing diarylamine antioxidants. The Journal of Organic Chemistry. 77: 6895-907. PMID 22788527 DOI: 10.1021/Jo301012X  0.51
2012 Amorati R, Lynett PT, Valgimigli L, Pratt DA. The reaction of sulfenic acids with peroxyl radicals: insights into the radical-trapping antioxidant activity of plant-derived thiosulfinates. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 6370-9. PMID 22473818 DOI: 10.1002/Chem.201103459  0.471
2012 Hanthorn JJ, Valgimigli L, Pratt DA. Incorporation of ring nitrogens into diphenylamine antioxidants: striking a balance between reactivity and stability. Journal of the American Chemical Society. 134: 8306-9. PMID 22369282 DOI: 10.1021/Ja300086Z  0.418
2012 Hanthorn JJ, Pratt DA. Peroxyesters as precursors to peroxyl radical clocks. The Journal of Organic Chemistry. 77: 276-84. PMID 22050531 DOI: 10.1021/Jo201862S  0.491
2011 Pratt DA, Tallman KA, Porter NA. Free radical oxidation of polyunsaturated lipids: New mechanistic insights and the development of peroxyl radical clocks. Accounts of Chemical Research. 44: 458-67. PMID 21486044 DOI: 10.1021/Ar200024C  0.629
2011 Lynett PT, Butts K, Vaidya V, Garrett GE, Pratt DA. The mechanism of radical-trapping antioxidant activity of plant-derived thiosulfinates. Organic & Biomolecular Chemistry. 9: 3320-30. PMID 21445384 DOI: 10.1039/C1Ob05192J  0.451
2011 Griesser M, Pistis V, Suzuki T, Tejera N, Pratt DA, Schneider C. Autoxidative and cyclooxygenase-2 catalyzed transformation of the dietary chemopreventive agent curcumin. The Journal of Biological Chemistry. 286: 1114-24. PMID 21071447 DOI: 10.1074/Jbc.M110.178806  0.636
2010 McGrath AJ, Garrett GE, Valgimigli L, Pratt DA. The redox chemistry of sulfenic acids. Journal of the American Chemical Society. 132: 16759-61. PMID 21049943 DOI: 10.1021/Ja1083046  0.361
2010 Serwa R, Nam TG, Valgimigli L, Culbertson S, Rector CL, Jeong BS, Pratt DA, Porter NA. Preparation and investigation of vitamin B6-derived aminopyridinol antioxidants. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 14106-14. PMID 20967898 DOI: 10.1002/Chem.201001382  0.728
2010 Amorati R, Pedulli GF, Pratt DA, Valgimigli L. TEMPO reacts with oxygen-centered radicals under acidic conditions. Chemical Communications (Cambridge, England). 46: 5139-41. PMID 20544078 DOI: 10.1039/C0Cc00547A  0.371
2010 Foti MC, Amorati R, Pedulli GF, Daquino C, Pratt DA, Ingold KU. Influence of "remote" intramolecular hydrogen bonds on the stabilities of phenoxyl radicals and benzyl cations. The Journal of Organic Chemistry. 75: 4434-40. PMID 20527908 DOI: 10.1021/Jo100491A  0.566
2010 Hu D, Pratt DA. Secondary orbital interactions in the propagation steps of lipid peroxidation. Chemical Communications (Cambridge, England). 46: 3711-3. PMID 20390152 DOI: 10.1039/C0Cc00019A  0.41
2010 Nara SJ, Valgimigli L, Pedulli GF, Pratt DA. Tyrosine analogues for probing proton-coupled electron transfer processes in peptides and proteins. Journal of the American Chemical Society. 132: 863-72. PMID 20000763 DOI: 10.1021/Ja907921W  0.43
2010 Malmberg SM, Parent JS, Pratt DA, Whitney RA. Isomerization and elimination reactions of brominated poly(isobutylene- co -isoprene) Macromolecules. 43: 8456-8461. DOI: 10.1021/Ma1018268  0.395
2009 Nam TG, Nara SJ, Zagol-Ikapitte I, Cooper T, Valgimigli L, Oates JA, Porter NA, Boutaud O, Pratt DA. Pyridine and pyrimidine analogs of acetaminophen as inhibitors of lipid peroxidation and cyclooxygenase and lipoxygenase catalysis. Organic & Biomolecular Chemistry. 7: 5103-12. PMID 20024105 DOI: 10.1039/B912528K  0.718
2009 Valgimigli L, Amorati R, Petrucci S, Pedulli GF, Hu D, Hanthorn JJ, Pratt DA. Unexpected acid catalysis in reactions of peroxyl radicals with phenols. Angewandte Chemie (International Ed. in English). 48: 8348-51. PMID 19784983 DOI: 10.1002/Anie.200903360  0.417
2009 Vaidya V, Ingold KU, Pratt DA. Garlic: source of the ultimate antioxidants--sulfenic acids. Angewandte Chemie (International Ed. in English). 48: 157-60. PMID 19040240 DOI: 10.1002/Anie.200804560  0.602
2008 Nara SJ, Jha M, Brinkhorst J, Zemanek TJ, Pratt DA. A simple Cu-catalyzed coupling approach to substituted 3-pyridinol and 5-pyrimidinol antioxidants. The Journal of Organic Chemistry. 73: 9326-33. PMID 18975911 DOI: 10.1021/Jo801501E  0.36
2008 Brinkhorst J, Nara SJ, Pratt DA. Hock cleavage of cholesterol 5alpha-hydroperoxide: an ozone-free pathway to the cholesterol ozonolysis products identified in arterial plaque and brain tissue. Journal of the American Chemical Society. 130: 12224-5. PMID 18722442 DOI: 10.1021/Ja804162D  0.347
2008 Jha M, Pratt DA. Kinetic solvent effects on peroxyl radical reactions. Chemical Communications (Cambridge, England). 1252-4. PMID 18309434 DOI: 10.1039/B800369F  0.423
2008 Valgimigli L, Amorati R, Fumo MG, DiLabio GA, Pedulli GF, Ingold KU, Pratt DA. The unusual reaction of semiquinone radicals with molecular oxygen. The Journal of Organic Chemistry. 73: 1830-41. PMID 18260673 DOI: 10.1021/Jo7024543  0.604
2007 Nam TG, Rector CL, Kim HY, Sonnen AF, Meyer R, Nau WM, Atkinson J, Rintoul J, Pratt DA, Porter NA. Tetrahydro-1,8-naphthyridinol analogues of alpha-tocopherol as antioxidants in lipid membranes and low-density lipoproteins. Journal of the American Chemical Society. 129: 10211-9. PMID 17655300 DOI: 10.1021/Ja072371M  0.768
2007 Schneider C, Pratt DA, Porter NA, Brash AR. Control of oxygenation in lipoxygenase and cyclooxygenase catalysis. Chemistry & Biology. 14: 473-88. PMID 17524979 DOI: 10.1016/J.Chembiol.2007.04.007  0.557
2006 Pesavento RP, Pratt DA, Jeffers J, van der Donk WA. Model studies of the Cu(B) site of cytochrome c oxidase utilizing a Zn(II) complex containing an imidazole-phenol cross-linked ligand. Dalton Transactions (Cambridge, England : 2003). 3326-37. PMID 16820845 DOI: 10.1039/B516090A  0.766
2006 Roschek B, Tallman KA, Rector CL, Gillmore JG, Pratt DA, Punta C, Porter NA. Peroxyl radical clocks. The Journal of Organic Chemistry. 71: 3527-32. PMID 16626136 DOI: 10.1021/Jo0601462  0.757
2006 Furse KE, Pratt DA, Schneider C, Brash AR, Porter NA, Lybrand TP. Molecular dynamics simulations of arachidonic acid-derived pentadienyl radical intermediate complexes with COX-1 and COX-2: insights into oxygenation regio- and stereoselectivity. Biochemistry. 45: 3206-18. PMID 16519515 DOI: 10.1021/Bi052338H  0.558
2006 Furse KE, Pratt DA, Porter NA, Lybrand TP. Molecular dynamics simulations of arachidonic acid complexes with COX-1 and COX-2: insights into equilibrium behavior. Biochemistry. 45: 3189-205. PMID 16519514 DOI: 10.1021/Bi052337P  0.488
2006 Pratt DA, van der Donk WA. On the role of alkylcobalamins in the vitamin B12-catalyzed reductive dehalogenation of perchloroethylene and trichloroethylene. Chemical Communications (Cambridge, England). 558-60. PMID 16432582 DOI: 10.1039/B513624E  0.549
2005 Mulder P, Korth HG, Pratt DA, DiLabio GA, Valgimigli L, Pedulli GF, Ingold KU. Critical re-evaluation of the O-H bond dissociation enthalpy in phenol. The Journal of Physical Chemistry. A. 109: 2647-55. PMID 16833571 DOI: 10.1021/Jp047148F  0.494
2005 Kim HY, Pratt DA, Seal JR, Wijtmans M, Porter NA. Lipid-soluble 3-pyridinol antioxidants spare alpha-tocopherol and do not efficiently mediate peroxidation of cholesterol esters in human low-density lipoprotein. Journal of Medicinal Chemistry. 48: 6787-9. PMID 16250637 DOI: 10.1021/Jm0507173  0.736
2005 Pratt DA, Pesavento RP, van der Donk WA. Model studies of the histidine-tyrosine cross-link in cytochrome C oxidase reveal the flexible substituent effect of the imidazole moiety. Organic Letters. 7: 2735-8. PMID 15957934 DOI: 10.1021/Ol050916G  0.775
2005 McCauley KM, Pratt DA, Wilson SR, Shey J, Burkey TJ, van der Donk WA. Properties and reactivity of chlorovinylcobalamin and vinylcobalamin and their implications for vitamin B12-catalyzed reductive dechlorination of chlorinated alkenes. Journal of the American Chemical Society. 127: 1126-36. PMID 15669852 DOI: 10.1021/Ja048573P  0.766
2005 Pratt DA, van der Donk WA. Theoretical investigations into the intermediacy of chlorinated vinylcobalamins in the reductive dehalogenation of chlorinated ethylenes. Journal of the American Chemical Society. 127: 384-96. PMID 15631489 DOI: 10.1021/Ja047915O  0.597
2005 Nam T, Wijtmans M, Pratt DA, Porter NA. Regioselective addition of n-alkyllithiums to alpha,alpha '-disubstituted-1,8-naphthyridines: Synthesis of 6-amino-3-pyridinol analogs of alpha-tocopherol Synthesis. 2005: 1397-1404. DOI: 10.1055/S-2005-865308  0.649
2005 Nam TG, Wijtmans M, Pratt DA, Porter NA. Regioselective addition of n-alkyllithiums to α,α′- disubstituted-1,8-naphthyridines: Synthesis of 6-amino-3-pyridinol analogs of α-tocopherol Synthesis. 1397-1404. DOI: 10.1002/CHIN.200541153  0.571
2005 Van Der Donk WA, Pratt DA. Mechanistic aspects of chlorinated ethylene degradation by vitamin B12 Acs National Meeting Book of Abstracts. 230.  0.455
2004 Wijtmans M, Pratt DA, Brinkhorst J, Serwa R, Valgimigli L, Pedulli GF, Porter NA. Synthesis and reactivity of some 6-substituted-2,4-dimethyl-3-pyridinols, a novel class of chain-breaking antioxidants. The Journal of Organic Chemistry. 69: 9215-23. PMID 15609958 DOI: 10.1021/Jo048842U  0.765
2004 Pratt DA, Blake JA, Mulder P, Walton JC, Korth HG, Ingold KU. O-H bond dissociation enthalpies in oximes: order restored. Journal of the American Chemical Society. 126: 10667-75. PMID 15327325 DOI: 10.1021/Ja047566Y  0.505
2004 Riggins JN, Pratt DA, Voehler M, Daniels JS, Marnett LJ. Kinetics and mechanism of the general-acid-catalyzed ring-closure of the malondialdehyde-DNA adduct, N2-(3-oxo-1-propenyl)deoxyguanosine (N2OPdG-), to 3-(2'-Deoxy-beta-D-erythro-pentofuranosyl)pyrimido[1,2-alpha]purin- 10(3H)-one (M1dG). Journal of the American Chemical Society. 126: 10571-81. PMID 15327313 DOI: 10.1021/Ja040010Q  0.54
2004 Pratt DA, DiLabio GA, Mulder P, Ingold KU. Bond strengths of toluenes, anilines, and phenols: to hammett or not. Accounts of Chemical Research. 37: 334-40. PMID 15147174 DOI: 10.1021/Ar010010K  0.472
2004 Blake JA, Pratt DA, Lin S, Walton JC, Mulder P, Ingold KU. Thermolyses of O-phenyl oxime ethers. A new source of iminyl radicals and a new source of aryloxyl radicals. The Journal of Organic Chemistry. 69: 3112-20. PMID 15104450 DOI: 10.1021/Jo049927Y  0.529
2004 Blake JA, Ingold KU, Lin S, Mulder P, Pratt DA, Sheeller B, Walton JC. Thermal decomposition of O-benzyl ketoximes; role of reverse radical disproportionation. Organic & Biomolecular Chemistry. 2: 415-20. PMID 14747871 DOI: 10.1039/B313491A  0.527
2003 Valgimigli L, Brigati G, Pedulli GF, DiLabio GA, Mastragostino M, Arbizzani C, Pratt DA. The effect of ring nitrogen atoms on the homolytic reactivity of phenolic compounds: understanding the radical-scavenging ability of 5-pyrimidinols. Chemistry (Weinheim An Der Bergstrasse, Germany). 9: 4997-5010. PMID 14562318 DOI: 10.1002/Chem.200304960  0.51
2003 Wijtmans M, Pratt DA, Valgimigli L, DiLabio GA, Pedulli GF, Porter NA. 6-Amino-3-pyridinols: towards diffusion-controlled chain-breaking antioxidants. Angewandte Chemie (International Ed. in English). 42: 4370-3. PMID 14502714 DOI: 10.1002/Anie.200351881  0.462
2003 Pratt DA, Mills JH, Porter NA. Theoretical calculations of carbon-oxygen bond dissociation enthalpies of peroxyl radicals formed in the autoxidation of lipids. Journal of the American Chemical Society. 125: 5801-10. PMID 12733921 DOI: 10.1021/Ja034182J  0.571
2003 Pratt DA, Porter NA. Role of hyperconjugation in determining carbon-oxygen bond dissociation enthalpies in alkylperoxyl radicals. Organic Letters. 5: 387-90. PMID 12583725 DOI: 10.1021/Ol027094X  0.568
2002 Pratt DA, DiLabio GA, Valgimigli L, Pedulli GF, Ingold KU. Substituent effects on the bond dissociation enthalpies of aromatic amines. Journal of the American Chemical Society. 124: 11085-92. PMID 12224956 DOI: 10.1021/Ja026289X  0.515
2002 Feng H, Kavrakova IK, Pratt DA, Tellinghuisen J, Porter NA. Lewis acid-promoted Kharasch-Curran additions: a competition kinetics study of bromine atom transfer addition of N-alpha-bromoacetyl-oxazolidinone to 1-hexene. The Journal of Organic Chemistry. 67: 6050-4. PMID 12182641 DOI: 10.1021/Jo0201676  0.647
2002 DiLabio GA, Litwinienko G, Lin S, Pratt DA, Ingold KU. Revised structure for the diphenylaminyl radical: The importance of theory in the assignment of electronic transitions in Ph2Ẋ (X = CH, N) and PhẎ (Y = CH2, NH, O) Journal of Physical Chemistry A. 106: 11719-11725. DOI: 10.1021/Jp026279I  0.488
2002 Feng H, Kavrakova IK, Pratt DA, Tellinghuisen J, Porter NA. Lewis acid-promoted kharasch-curran additions: A competition kinetics study of bromine atom transfer addition of N-α-bromoacetyl-oxazolidinone to 1-hexene Journal of Organic Chemistry. 67: 6050-6054. DOI: 10.1021/jo0201676  0.45
2001 Tallman KA, Pratt DA, Porter NA. Kinetic products of linoleate peroxidation: rapid beta-fragmentation of nonconjugated peroxyls. Journal of the American Chemical Society. 123: 11827-8. PMID 11716752 DOI: 10.1021/Ja0169724  0.473
2001 Pratt DA, DiLabio GA, Brigati G, Pedulli GF, Valgimigli L. 5-Pyrimidinols: novel chain-breaking antioxidants more effective than phenols. Journal of the American Chemical Society. 123: 4625-6. PMID 11457259 DOI: 10.1021/Ja005679L  0.339
2001 Pratt DA, de Heer MI, Mulder P, Ingold KU. Oxygen-carbon bond dissociation enthalpies of benzyl phenyl ethers and anisoles. An example of temperature dependent substituent effects. Journal of the American Chemical Society. 123: 5518-26. PMID 11389634 DOI: 10.1021/ja004081a  0.421
2000 DiLabio GA, Pratt DA, Wright JS. Theoretical calculation of ionization potentials for disubstituted benzenes: additivity vs non-additivity of substituent effects The Journal of Organic Chemistry. 65: 2195-203. PMID 10774046 DOI: 10.1021/Jo991833E  0.303
2000 Reints W, Pratt DA, Korth HG, Mulder P. O-O bond dissociation enthalpy in Di(trifluoromethyl) peroxide (CF3OOCF3) as determined by very low pressure pyrolysis. Density functional theory computations on O-O and O-H bonds in (fluorinated) derivatives Journal of Physical Chemistry A. 104: 10713-10720. DOI: 10.1021/Jp994434W  0.35
2000 Porter NA, Yin H, Pratt DA. The peroxy acid dioxirane equilibrium: Base-promoted exchange of peroxy acid oxygens [24] Journal of the American Chemical Society. 122: 11272-11273. DOI: 10.1021/Ja005648Q  0.59
1999 Dilabio GA, Pratt DA, LoFaro AD, Wright JS. Theoretical study of X - H bond energetics (X = C, N, O, S): Application to substituent effects, gas phase acidities, and redox potentials Journal of Physical Chemistry A. 103: 1653-1661. DOI: 10.1021/Jp984369A  0.391
1999 Pratt DA, Wright JS, Ingold KU. Theoretical study of carbon-halogen bond dissociation enthalpies of substituted benzyl halides. How important are polar effects? Journal of the American Chemical Society. 121: 4877-4882. DOI: 10.1021/ja982866z  0.395
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