Year |
Citation |
Score |
2023 |
Bandy R, Shahi S, Quagraine N, Shahbazi Nia S, Howlader MSI, Srivenugopal K, Stephan C, Das H, Mikelis CM, German NA. Mechanistic Aspects of Biphenyl Urea-Based Analogues in Triple-Negative Breast Cancer Cell Lines. Acs Pharmacology & Translational Science. 7: 120-136. PMID 38230276 DOI: 10.1021/acsptsci.3c00193 |
0.624 |
|
2023 |
Shahbazi Nia S, Hossain MA, Ji G, Jonnalagadda SK, Obeng S, Rahman MA, Sifat AE, Nozohouri S, Blackwell C, Patel D, Thompson J, Runyon S, Hiranita T, McCurdy CR, McMahon L, ... ... German NA, et al. Studies on diketopiperazine and dipeptide analogs as opioid receptor ligands. European Journal of Medicinal Chemistry. 254: 115309. PMID 37054561 DOI: 10.1016/j.ejmech.2023.115309 |
0.614 |
|
2022 |
Ashraf-Uz-Zaman M, Ji G, Tidwell D, Yin L, Thakolwiboon S, Pan J, Junell R, Griffin Z, Shahi S, Barthels D, Sajib MS, Trippier PC, Mikelis CM, Das H, Avila M, ... ... German NA, et al. Evaluation of Urea-Based Inhibitors of the Dopamine Transporter Using the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis. Acs Chemical Neuroscience. PMID 34978174 DOI: 10.1021/acschemneuro.1c00647 |
0.699 |
|
2021 |
Hossain MA, German NA. Update on modulators of quorum sensing pathways in Pseudomonas Aeruginosa. Current Topics in Medicinal Chemistry. PMID 34561982 DOI: 10.2174/1568026621666210924160004 |
0.614 |
|
2021 |
Al-Hilal TA, Hossain MA, Alobaida A, Alam F, Keshavarz A, Nozik-Grayck E, Stenmark KR, German NA, Ahsan F. Design, synthesis and biological evaluations of a long-acting, hypoxia-activated prodrug of fasudil, a ROCK inhibitor, to reduce its systemic side-effects. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 33915222 DOI: 10.1016/j.jconrel.2021.04.030 |
0.613 |
|
2020 |
Ashraf-Uz-Zaman M, Shahi S, Akwii R, Sajib MS, Farshbaf MJ, Kallem RR, Putnam W, Wang W, Zhang R, Alvina K, Trippier PC, Mikelis CM, German NA. Design, synthesis and structure-activity relationship study of novel urea compounds as FGFR1 inhibitors to treat metastatic triple-negative breast cancer. European Journal of Medicinal Chemistry. 209: 112866. PMID 33039722 DOI: 10.1016/j.ejmech.2020.112866 |
0.714 |
|
2020 |
Ashraf-Uz-Zaman M, Bhalerao A, Mikelis CM, Cucullo L, German NA. Assessing the Current State of Lung Cancer Chemoprevention: A Comprehensive Overview. Cancers. 12. PMID 32429547 DOI: 10.3390/cancers12051265 |
0.707 |
|
2019 |
Hossain MA, Sattenapally N, Parikh HI, Li W, Rumbaugh KP, German NA. Design, synthesis, and evaluation of compounds capable of reducing Pseudomonas aeruginosa virulence. European Journal of Medicinal Chemistry. 111800. PMID 31706639 DOI: 10.1016/J.Ejmech.2019.111800 |
0.642 |
|
2018 |
Ashraf-Uz-Zaman M, Sajib MS, Cucullo L, Mikelis CM, German NA. Analogs of penfluridol as chemotherapeutic agents with reduced central nervous system activity. Bioorganic & Medicinal Chemistry Letters. PMID 30389290 DOI: 10.1016/j.bmcl.2018.10.036 |
0.737 |
|
2018 |
Nguyen T, Gamage TF, Decker AM, German N, Langston TL, Farquhar CE, Kenakin TP, Wiley JL, Thomas BF, Zhang Y. Diarylureas Containing 5-Membered Heterocycles as CB1 Receptor Allosteric Modulators: Design, Synthesis, and Pharmacological Evaluation. Acs Chemical Neuroscience. PMID 30188693 DOI: 10.1021/Acschemneuro.8B00396 |
0.339 |
|
2018 |
Dukat M, Jain AD, German N, Ferrara-Pontoriero R, Huang Y, Ma Y, Schulte MK, Glennon RA. des-Formylflustrabromine (dFBr): A Structure-Activity Study on its Ability to Potentiate the Action of Acetylcholine at α4β2 Nicotinic Acetylcholine Receptors. Acs Chemical Neuroscience. PMID 30028943 DOI: 10.1021/Acschemneuro.8B00156 |
0.617 |
|
2018 |
Patel R, Hossain MA, German N, Al-Ahmad AJ. Gliotoxin penetrates and impairs the integrity of the human blood-brain barrier in vitro. Mycotoxin Research. PMID 30006720 DOI: 10.1007/S12550-018-0320-7 |
0.57 |
|
2017 |
Nguyen T, German N, Decker AM, Langston TL, Gamage TF, Farquhar CE, Li JX, Wiley JL, Thomas BF, Zhang Y. Novel Diarylurea Based Allosteric Modulators of the Cannabinoid CB1 Receptor: Evaluation of Importance of 6-Pyrrolidinylpyridinyl Substitution. Journal of Medicinal Chemistry. PMID 28792219 DOI: 10.1021/Acs.Jmedchem.7B00707 |
0.366 |
|
2015 |
Nguyen T, German N, Decker AM, Li JX, Wiley JL, Thomas BF, Kenakin TP, Zhang Y. Structure-activity relationships of substituted 1H-indole-2-carboxamides as CB1 receptor allosteric modulators. Bioorganic & Medicinal Chemistry. 23: 2195-203. PMID 25797163 DOI: 10.1016/J.Bmc.2015.02.058 |
0.408 |
|
2015 |
Perrey DA, German NA, Decker AM, Thorn D, Li JX, Gilmour BP, Thomas BF, Harris DL, Runyon SP, Zhang Y. Effect of 1-substitution on tetrahydroisoquinolines as selective antagonists for the orexin-1 receptor. Acs Chemical Neuroscience. 6: 599-614. PMID 25643283 DOI: 10.1016/J.Drugalcdep.2015.07.659 |
0.401 |
|
2015 |
Zhang Y, Perrey DA, Harris DL, German NA, Decker AM, Gilmour BP, Thomas BF. Structure-activity relationship studies on the tetrahydroisoquinoline-based orexin 1 receptor antagonists: The 1-benzyl position Drug and Alcohol Dependence. 146. DOI: 10.1016/J.Drugalcdep.2014.09.765 |
0.319 |
|
2014 |
German N, Decker AM, Gilmour BP, Gay EA, Wiley JL, Thomas BF, Zhang Y. Diarylureas as allosteric modulators of the cannabinoid CB1 receptor: structure-activity relationship studies on 1-(4-chlorophenyl)-3-{3-[6-(pyrrolidin-1-yl)pyridin-2-yl]phenyl}urea (PSNCBAM-1). Journal of Medicinal Chemistry. 57: 7758-69. PMID 25162172 DOI: 10.1021/Jm501042U |
0.354 |
|
2013 |
Perrey DA, German NA, Gilmour BP, Li JX, Harris DL, Thomas BF, Zhang Y. Substituted tetrahydroisoquinolines as selective antagonists for the orexin 1 receptor. Journal of Medicinal Chemistry. 56: 6901-16. PMID 23941044 DOI: 10.1021/Jm400720H |
0.366 |
|
2011 |
German N, Kim JS, Jain A, Dukat M, Pandya A, Ma Y, Weltzin M, Schulte MK, Glennon RA. Deconstruction of the α4β2 nicotinic acetylcholine receptor positive allosteric modulator desformylflustrabromine Journal of Medicinal Chemistry. 54: 7259-7267. PMID 21905680 DOI: 10.1021/Jm200834X |
0.587 |
|
2010 |
Malik M, Marks KR, Schwanz HA, German N, Drlica K, Kerns RJ. Effect of N-1/c-8 ring fusion and C-7 ring structure on fluoroquinolone lethality. Antimicrobial Agents and Chemotherapy. 54: 5214-21. PMID 20855738 DOI: 10.1128/Aac.01054-10 |
0.708 |
|
2009 |
Rosen JD, German N, Kerns RJ. Efficient Synthesis of the 2-amino-6-chloro-4-cyclopropyl-7-fluoro-5-methoxy-pyrido[1,2-c]pyrimidine-1,3-dione core ring system. Tetrahedron Letters. 50: 785-789. PMID 20160840 DOI: 10.1016/J.Tetlet.2008.11.121 |
0.624 |
|
2008 |
German N, Malik M, Rosen JD, Drlica K, Kerns RJ. Use of gyrase resistance mutants to guide selection of 8-methoxy-quinazoline-2,4-diones. Antimicrobial Agents and Chemotherapy. 52: 3915-21. PMID 18765690 DOI: 10.1128/Aac.00330-08 |
0.594 |
|
2008 |
German N, Wei P, Kaatz GW, Kerns RJ. Synthesis and evaluation of fluoroquinolone derivatives as substrate-based inhibitors of bacterial efflux pumps. European Journal of Medicinal Chemistry. 43: 2453-63. PMID 18358571 DOI: 10.1016/J.Ejmech.2008.01.042 |
0.609 |
|
2008 |
German N, Kaatz GW, Kerns RJ. Synthesis and evaluation of PSSRI-based inhibitors of Staphylococcus aureus multidrug efflux pumps. Bioorganic & Medicinal Chemistry Letters. 18: 1368-73. PMID 18242086 DOI: 10.1016/J.Bmcl.2008.01.014 |
0.635 |
|
Show low-probability matches. |