Hiromitsu Nakauchi - Publications

Affiliations: 
Institute for Stem Cell Biology and Regenerative Medicine Stanford University School of Medicine, Palo Alto, CA, United States 

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Year Citation  Score
2024 Niizuma K, Morikawa S, Gars E, Xiang J, Matsubara-Takahashi T, Saito R, Takematsu E, Wang Y, Xu H, Wakimoto A, Tan TK, Kubota Y, Chan CKF, Weissman IL, Nakagawa T, ... ... Nakauchi H, et al. Elevated hematopoietic stem cell frequency in mouse alveolar bone marrow. Stem Cell Reports. 102374. PMID 39672154 DOI: 10.1016/j.stemcr.2024.11.004  0.342
2024 Suchy FP, Karigane D, Nakauchi Y, Higuchi M, Zhang J, Pekrun K, Hsu I, Fan AC, Nishimura T, Charlesworth CT, Bhadury J, Nishimura T, Wilkinson AC, Kay MA, Majeti R, ... Nakauchi H, et al. Genome engineering with Cas9 and AAV repair templates generates frequent concatemeric insertions of viral vectors. Nature Biotechnology. PMID 38589662 DOI: 10.1038/s41587-024-02171-w  0.716
2024 Fowler JL, Zheng SL, Nguyen A, Chen A, Xiong X, Chai T, Chen JY, Karigane D, Banuelos AM, Niizuma K, Kayamori K, Nishimura T, Cromer MK, Gonzalez-Perez D, Mason C, ... ... Nakauchi H, et al. Lineage-tracing hematopoietic stem cell origins in vivo to efficiently make human HLF+ HOXA+ hematopoietic progenitors from pluripotent stem cells. Developmental Cell. PMID 38569552 DOI: 10.1016/j.devcel.2024.03.003  0.785
2024 Kinoshita S, Ishii M, Ando J, Kimura T, Yamaguchi T, Harada S, Takahashi F, Nakashima K, Nakazawa Y, Yamazaki S, Ohshima K, Takahashi K, Nakauchi H, Ando M. Rejuvenated iPSC-derived GD2-directed CART Cells Harbor Robust Cytotoxicity Against Small Cell Lung Cancer. Cancer Research Communications. 4: 723-737. PMID 38380966 DOI: 10.1158/2767-9764.CRC-23-0259  0.327
2024 Okubo T, Rivron N, Kabata M, Masaki H, Kishimoto K, Semi K, Nakajima-Koyama M, Kunitomi H, Kaswandy B, Sato H, Nakauchi H, Woltjen K, Saitou M, Sasaki E, Yamamoto T, et al. Publisher Correction: Hypoblast from human pluripotent stem cells regulates epiblast development. Nature. 626: E21. PMID 38347193 DOI: 10.1038/s41586-024-07166-w  0.39
2023 Okubo T, Rivron N, Kabata M, Masaki H, Kishimoto K, Semi K, Nakajima-Koyama M, Kunitomi H, Kaswandy B, Sato H, Nakauchi H, Woltjen K, Saitou M, Sasaki E, Yamamoto T, et al. Hypoblast from human pluripotent stem cells regulates epiblast development. Nature. PMID 38052228 DOI: 10.1038/s41586-023-06871-2  0.363
2023 Sakurai M, Ishitsuka K, Ito R, Wilkinson AC, Kimura T, Mizutani E, Nishikii H, Sudo K, Becker HJ, Takemoto H, Sano T, Kataoka K, Takahashi S, Nakamura Y, Kent DG, ... ... Nakauchi H, et al. Chemically defined cytokine-free expansion of human haematopoietic stem cells. Nature. 615: 127-133. PMID 36813966 DOI: 10.1038/s41586-023-05739-9  0.387
2023 Igarashi KJ, Kucinski I, Chan YY, Tan TK, Khoo HM, Kealy D, Bhadury J, Hsu I, Ho PY, Niizuma K, Hickey JW, Nolan G, Bridge KS, Czechowicz A, Gottgens B, ... Nakauchi H, et al. Physioxia improves the selectivity of hematopoietic stem cell expansion cultures. Blood Advances. PMID 36809781 DOI: 10.1182/bloodadvances.2023009668  0.564
2022 Roodgar M, Suchy FP, Nguyen LH, Bajpai VK, Sinha R, Vilches-Moure JG, Van Bortle K, Bhadury J, Metwally A, Jiang L, Jian R, Chiang R, Oikonomopoulos A, Wu JC, Weissman IL, ... ... Nakauchi H, et al. Chimpanzee and pig-tailed macaque iPSCs: Improved culture and generation of primate cross-species embryos. Cell Reports. 40: 111264. PMID 36044843 DOI: 10.1016/j.celrep.2022.111264  0.305
2022 Che JLC, Bode D, Kucinski I, Cull AH, Bain F, Becker HJ, Jassinskaja M, Barile M, Boyd G, Belmonte M, Zeng AGX, Igarashi KJ, Rubio-Lara J, Shepherd MS, Clay A, ... ... Nakauchi H, et al. Identification and characterization of in vitro expanded hematopoietic stem cells. Embo Reports. e55502. PMID 35971894 DOI: 10.15252/embr.202255502  0.375
2022 Nishimura T, Niizuma K, Nakauchi H. Bioluminescent Tracking of Human Induced Pluripotent Stem Cells In Vitro and In Vivo. Methods in Molecular Biology (Clifton, N.J.). 2524: 291-297. PMID 35821480 DOI: 10.1007/978-1-0716-2453-1_22  0.773
2022 Ang LT, Nguyen AT, Liu KJ, Chen A, Xiong X, Curtis M, Martin RM, Raftry BC, Ng CY, Vogel U, Lander A, Lesch BJ, Fowler JL, Holman AR, Chai T, ... ... Nakauchi H, et al. Generating human artery and vein cells from pluripotent stem cells highlights the arterial tropism of Nipah and Hendra viruses. Cell. PMID 35738284 DOI: 10.1016/j.cell.2022.05.024  0.734
2022 Oikawa M, Kobayashi H, Sanbo M, Mizuno N, Iwatsuki K, Takashima T, Yamauchi K, Yoshida F, Yamamoto T, Shinohara T, Nakauchi H, Kurimoto K, Hirabayashi M, Kobayashi T. Functional primordial germ cell-like cells from pluripotent stem cells in rats. Science (New York, N.Y.). 376: 176-179. PMID 35389778 DOI: 10.1126/science.abl4412  0.362
2022 Charlesworth CT, Hsu I, Wilkinson AC, Nakauchi H. Immunological barriers to haematopoietic stem cell gene therapy. Nature Reviews. Immunology. PMID 35301483 DOI: 10.1038/s41577-022-00698-0  0.31
2022 Shibuya Y, Kumar KK, Mader MM, Yoo Y, Ayala LA, Zhou M, Mohr MA, Neumayer G, Kumar I, Yamamoto R, Marcoux P, Liou B, Bennett FC, Nakauchi H, Sun Y, et al. Treatment of a genetic brain disease by CNS-wide microglia replacement. Science Translational Medicine. 14: eabl9945. PMID 35294256 DOI: 10.1126/scitranslmed.abl9945  0.321
2022 Yamazaki K, Kubara K, Ishii S, Li P, Dairiki R, Hihara T, Ishizuka Y, Izumi Y, Kumai M, Kamisako T, Ishizaki H, Sato H, Masaki H, Mizuno N, Mitsuhashi K, ... ... Nakauchi H, et al. In vitro and in vivo functions of T cells produced in complemented thymi of chimeric mice generated by blastocyst complementation. Scientific Reports. 12: 3242. PMID 35217706 DOI: 10.1038/s41598-022-07159-7  0.337
2022 Furukawa Y, Hamano Y, Shirane S, Kinoshita S, Azusawa Y, Ando J, Nakauchi H, Ando M. Advances in Allogeneic Cancer Cell Therapy and Future Perspectives on "Off-the-Shelf" T Cell Therapy Using iPSC Technology and Gene Editing. Cells. 11. PMID 35053386 DOI: 10.3390/cells11020269  0.37
2021 Kinoshita M, Kobayashi T, Planells B, Klisch D, Spindlow D, Masaki H, Bornelöv S, Stirparo GG, Matsunari H, Uchikura A, Lamas-Toranzo I, Nichols J, Nakauchi H, Nagashima H, Alberio R, et al. Pluripotent stem cells related to embryonic disc exhibit common self-renewal requirements in diverse livestock species. Development (Cambridge, England). 148. PMID 34874452 DOI: 10.1242/dev.199901  0.435
2021 Kobayashi T, Castillo-Venzor A, Penfold CA, Morgan M, Mizuno N, Tang WWC, Osada Y, Hirao M, Yoshida F, Sato H, Nakauchi H, Hirabayashi M, Surani MA. Tracing the emergence of primordial germ cells from bilaminar disc rabbit embryos and pluripotent stem cells. Cell Reports. 37: 109812. PMID 34644585 DOI: 10.1016/j.celrep.2021.109812  0.376
2021 Harada S, Ando M, Ando J, Ishii M, Yamaguchi T, Yamazaki S, Toyota T, Ohara K, Ohtaka M, Nakanishi M, Shin C, Ota Y, Nakashima K, Ohshima K, Imai C, ... ... Nakauchi H, et al. Dual-antigen targeted iPSC-derived chimeric antigen receptor-T cell therapy for refractory lymphoma. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 34628050 DOI: 10.1016/j.ymthe.2021.10.006  0.323
2021 Sudo K, Yamazaki S, Wilkinson AC, Nakauchi H, Nakamura Y. Polyvinyl alcohol hydrolysis rate and molecular weight influence human and murine HSC activity ex vivo. Stem Cell Research. 56: 102531. PMID 34509158 DOI: 10.1016/j.scr.2021.102531  0.328
2021 Hyun I, Clayton EW, Cong Y, Fujita M, Goldman SA, Hill LR, Monserrat N, Nakauchi H, Pedersen RA, Rooke HM, Takahashi J, Knoblich JA. ISSCR guidelines for the transfer of human pluripotent stem cells and their direct derivatives into animal hosts. Stem Cell Reports. PMID 34048695 DOI: 10.1016/j.stemcr.2021.05.005  0.342
2021 Lovell-Badge R, Anthony E, Barker RA, Bubela T, Brivanlou AH, Carpenter M, Charo RA, Clark A, Clayton E, Cong Y, Daley GQ, Fu J, Fujita M, Greenfield A, Goldman SA, ... ... Nakauchi H, et al. ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update. Stem Cell Reports. PMID 34048692 DOI: 10.1016/j.stemcr.2021.05.012  0.342
2021 Wilkinson AC, Dever DP, Baik R, Camarena J, Hsu I, Charlesworth CT, Morita C, Nakauchi H, Porteus MH. Cas9-AAV6 gene correction of beta-globin in autologous HSCs improves sickle cell disease erythropoiesis in mice. Nature Communications. 12: 686. PMID 33514718 DOI: 10.1038/s41467-021-20909-x  0.339
2020 Yamamoto R, Nakauchi H. In vivo clonal analysis of aging hematopoietic stem cells. Mechanisms of Ageing and Development. 111378. PMID 33022333 DOI: 10.1016/j.mad.2020.111378  0.316
2020 Honda T, Ando M, Ando J, Ishii M, Sakiyama Y, Ohara K, Toyota T, Ohtaka M, Masuda A, Terao Y, Nakanishi M, Nakauchi H, Komatsu N. Sustainable Tumor-Suppressive Effect of iPSC-Derived Rejuvenated T Cells Targeting Cervical Cancers. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 32710827 DOI: 10.1016/J.Ymthe.2020.07.004  0.355
2020 Nishimura T, Xu H, Iwasaki M, Karigane D, Saavedra B, Takahashi Y, Suchy FP, Monobe S, Martin RM, Ohtaka M, Nakanishi M, Burrows SR, Cleary ML, Majeti R, Shibuya A, ... Nakauchi H, et al. Sufficiency for inducible Caspase-9 safety switch in human pluripotent stem cells and disease cells. Gene Therapy. PMID 32704085 DOI: 10.1038/S41434-020-0179-Z  0.784
2020 Wilkes MC, Siva K, Chen J, Varetti G, Youn MY, Chae H, Ek F, Olsson R, Lundbäck T, Dever DP, Nishimura T, Narla A, Glader B, Nakauchi H, Porteus MH, et al. Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase. Nature Communications. 11: 3344. PMID 32620751 DOI: 10.1038/S41467-020-17100-Z  0.733
2020 Wilkinson AC, Nakauchi H. Stabilizing hematopoietic stem cells in vitro. Current Opinion in Genetics & Development. 64: 1-5. PMID 32570191 DOI: 10.1016/J.Gde.2020.05.035  0.498
2020 Onodera S, Saito A, Hojo H, Nakamura T, Zujur D, Watanabe K, Morita N, Hasegawa D, Masaki H, Nakauchi H, Nomura T, Shibahara T, Yamaguchi A, Chung UI, Azuma T, et al. Hedgehog Activation Regulates Human Osteoblastogenesis. Stem Cell Reports. PMID 32531191 DOI: 10.1016/J.Stemcr.2020.05.008  0.35
2020 Wilkinson AC, Igarashi KJ, Nakauchi H. Haematopoietic stem cell self-renewal in vivo and ex vivo. Nature Reviews. Genetics. 21: 541-554. PMID 32467607 DOI: 10.1038/S41576-020-0241-0  0.438
2020 Yamamoto R, Wilkinson AC, Nakauchi H. In vivo and ex vivo haematopoietic stem cell expansion. Current Opinion in Hematology. PMID 32452877 DOI: 10.1097/Moh.0000000000000593  0.481
2020 Choudhury AR, Ju Z, Djojosubroto MW, Schienke A, Lechel A, Schaetzlein S, Jiang H, Stepczynska A, Wang C, Buer J, Lee HW, von Zglinicki T, Ganser A, Schirmacher P, Nakauchi H, et al. Author Correction: Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation. Nature Genetics. PMID 32355231 DOI: 10.1038/S41588-020-0593-6  0.393
2020 Sato A, Kakinuma S, Miyoshi M, Kamiya A, Tsunoda T, Kaneko S, Tsuchiya J, Shimizu T, Takeichi E, Nitta S, Kawai-Kitahata F, Murakawa M, Itsui Y, Nakagawa M, Azuma S, ... ... Nakauchi H, et al. Vasoactive Intestinal Peptide Derived From Liver Mesenchymal Cells Mediates Tight Junction Assembly in Mouse Intrahepatic Bile Ducts. Hepatology Communications. 4: 235-254. PMID 32025608 DOI: 10.1002/hep4.1459  0.311
2020 Kobayashi T, Kobayashi H, Goto T, Takashima T, Oikawa M, Ikeda H, Terada R, Yoshida F, Sanbo M, Nakauchi H, Kurimoto K, Hirabayashi M. Germline development in rat revealed by visualization and deletion of . Development (Cambridge, England). PMID 32001439 DOI: 10.1242/Dev.183798  0.309
2020 Zujur D, Kanke K, Onodera S, Tani S, Lai J, Azuma T, Xin X, Lichtler AC, Rowe DW, Saito T, Tanaka S, Masaki H, Nakauchi H, Chung UI, Hojo H, et al. Stepwise strategy for generating osteoblasts from human pluripotent stem cells under fully defined xeno-free conditions with small-molecule inducers. Regenerative Therapy. 14: 19-31. PMID 31988991 DOI: 10.1016/J.Reth.2019.12.010  0.456
2020 Wilkinson AC, Ishida R, Nakauchi H, Yamazaki S. Long-term ex vivo expansion of mouse hematopoietic stem cells. Nature Protocols. PMID 31915389 DOI: 10.1038/S41596-019-0263-2  0.48
2020 Ando M, Ando J, Honda T, Ishii M, Nakauchi H, Komatsu N. iPSC-derived Rejuvenated T-cell Therapy for Extranodal NK/T-cell Lymphoma, Nasal Type Juntendo Medical Journal. 66: 200-205. DOI: 10.14789/Jmj.2020.66.Jmj20-R03  0.384
2020 Wilkes MC, Chae H, Wentworth EP, Nishimura T, Narla A, Glader B, Nakauchi H, Wysocka J, Sakamoto KM. SATB1 Regulates GATA1 Protein Expression in Early Hematopoiesis and Is Deregulated in Diamond Blackfan Anemia Blood. 136: 3-3. DOI: 10.1182/blood-2020-140437  0.746
2019 Matsunari H, Watanabe M, Hasegawa K, Uchikura A, Nakano K, Umeyama K, Masaki H, Hamanaka S, Yamaguchi T, Nagaya M, Nishinakamura R, Nakauchi H, Nagashima H. Compensation of Disabled Organogeneses in Genetically Modified Pig Fetuses by Blastocyst Complementation. Stem Cell Reports. PMID 31883918 DOI: 10.1016/J.Stemcr.2019.11.008  0.369
2019 Nishimura T, Hsu I, Martinez-Krams DC, Nakauchi Y, Majeti R, Yamazaki S, Nakauchi H, Wilkinson AC. Use of polyvinyl alcohol for chimeric antigen receptor T-cell expansion. Experimental Hematology. PMID 31874780 DOI: 10.1016/J.Exphem.2019.11.007  0.756
2019 Mori M, Furuhashi K, Danielsson JA, Hirata Y, Kakiuchi M, Lin CS, Ohta M, Riccio P, Takahashi Y, Xu X, Emala CW, Lu C, Nakauchi H, Cardoso WV. Generation of functional lungs via conditional blastocyst complementation using pluripotent stem cells. Nature Medicine. PMID 31700187 DOI: 10.1038/S41591-019-0635-8  0.337
2019 Kawata M, Mori D, Kanke K, Hojo H, Ohba S, Chung UI, Yano F, Masaki H, Otsu M, Nakauchi H, Tanaka S, Saito T. Simple and Robust Differentiation of Human Pluripotent Stem Cells toward Chondrocytes by Two Small-Molecule Compounds. Stem Cell Reports. PMID 31402337 DOI: 10.1016/J.Stemcr.2019.07.012  0.442
2019 Villanueva J, Nishimura T, Nakauchi H. Using the Inducible Caspase-9 Suicide-Safeguard System with iPSC and Bioluminescent Tracking. Methods in Molecular Biology (Clifton, N.J.). 2048: 259-264. PMID 31396943 DOI: 10.1007/978-1-4939-9728-2_20  0.755
2019 Nishimura T, Murmann Y, Nakauchi H. Human iPSC Generation from Antigen-Specific T Cells. Methods in Molecular Biology (Clifton, N.J.). 2048: 53-57. PMID 31396928 DOI: 10.1007/978-1-4939-9728-2_5  0.777
2019 Ghosn E, Yoshimoto M, Nakauchi H, Weissman IL, Herzenberg LA. Hematopoietic stem cell-independent hematopoiesis and the origins of innate-like B lymphocytes. Development (Cambridge, England). 146. PMID 31371526 DOI: 10.1242/Dev.170571  0.473
2019 Segal JM, Kent D, Wesche DJ, Ng SS, Serra M, Oulès B, Kar G, Emerton G, Blackford SJI, Darmanis S, Miquel R, Luong TV, Yamamoto R, Bonham A, Jassem W, ... ... Nakauchi H, et al. Single cell analysis of human foetal liver captures the transcriptional profile of hepatobiliary hybrid progenitors. Nature Communications. 10: 3350. PMID 31350390 DOI: 10.1038/S41467-019-11266-X  0.389
2019 Ando M, Ando J, Yamazaki S, Ishii M, Sakiyama Y, Harada S, Honda T, Yamaguchi T, Nojima M, Ohshima K, Nakauchi H, Komatsu N. Long-term eradication of extranodal NK/T cell lymphoma, nasal type, by induced pluripotent stem cell-derived Epstein-Barr virus-specific rejuvenated T cells . Haematologica. PMID 31296577 DOI: 10.3324/Haematol.2019.223511  0.467
2019 Wilkinson AC, Ishida R, Kikuchi M, Sudo K, Morita M, Crisostomo RV, Yamamoto R, Loh KM, Nakamura Y, Watanabe M, Nakauchi H, Yamazaki S. Author Correction: Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation. Nature. PMID 31289376 DOI: 10.1038/S41586-019-1395-9  0.415
2019 Wilkinson AC, Ishida R, Kikuchi M, Sudo K, Morita M, Crisostomo RV, Yamamoto R, Loh KM, Nakamura Y, Watanabe M, Nakauchi H, Yamazaki S. Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation. Nature. PMID 31142833 DOI: 10.1038/S41586-019-1244-X  0.481
2019 Watanabe M, Nakano K, Uchikura A, Matsunari H, Yashima S, Umeyama K, Takayanagi S, Sakuma T, Yamamoto T, Morita S, Horii T, Hatada I, Nishinakamura R, Nakauchi H, Nagashima H. Anephrogenic phenotype induced by SALL1 gene knockout in pigs. Scientific Reports. 9: 8016. PMID 31142767 DOI: 10.1038/S41598-019-44387-W  0.373
2019 Martin RM, Ikeda K, Cromer MK, Uchida N, Nishimura T, Romano R, Tong AJ, Lemgart VT, Camarena J, Pavel-Dinu M, Sindhu C, Wiebking V, Vaidyanathan S, Dever DP, Bak RO, ... ... Nakauchi H, et al. Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination. Cell Stem Cell. 24: 821-828.e5. PMID 31051134 DOI: 10.1016/J.Stem.2019.04.001  0.761
2019 Tsunoda T, Kakinuma S, Miyoshi M, Kamiya A, Kaneko S, Sato A, Tsuchiya J, Nitta S, Kawai-Kitahata F, Murakawa M, Itsui Y, Nakagawa M, Azuma S, Sogo T, Komatsu H, ... ... Nakauchi H, et al. Loss of Fibrocystin Promotes Interleukin-8-Dependent Proliferation and CTGF Production of Biliary Epithelium. Journal of Hepatology. PMID 30898581 DOI: 10.1016/J.Jhep.2019.02.024  0.336
2019 Miyoshi M, Kakinuma S, Kamiya A, Tsunoda T, Tsuchiya J, Sato A, Kaneko S, Nitta S, Kawai-Kitahata F, Murakawa M, Itsui Y, Nakagawa M, Azuma S, Nakauchi H, Asahina Y, et al. LIM homeobox 2 promotes interaction between human iPS-derived hepatic progenitors and iPS-derived hepatic stellate-like cells. Scientific Reports. 9: 2072. PMID 30765795 DOI: 10.1038/S41598-018-37430-9  0.499
2019 Goto T, Hara H, Sanbo M, Masaki H, Sato H, Yamaguchi T, Hochi S, Kobayashi T, Nakauchi H, Hirabayashi M. Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats. Nature Communications. 10: 451. PMID 30723213 DOI: 10.1038/S41467-019-08394-9  0.409
2019 Nishimura T, Nakauchi H. Generation of Antigen-Specific T Cells from Human Induced Pluripotent Stem Cells. Methods in Molecular Biology (Clifton, N.J.). 1899: 25-40. PMID 30649763 DOI: 10.1007/978-1-4939-8938-6_3  0.775
2019 Wilkinson A, Ishida R, Kikuchi M, Sudo K, Morita M, Crisostomo RV, Yamamoto R, Loh K, Nakamura Y, Watanabe M, Nakauchi H, Yamazaki S. 2001 - LONG-TERM EX VIVO EXPANSION OF FUNCTIONAL HEMATOPOIETIC STEM CELLS Experimental Hematology. 76: S42. DOI: 10.1016/J.Exphem.2019.06.276  0.417
2018 Ikeda K, Uchida N, Nishimura T, White J, Martin RM, Nakauchi H, Sebastiano V, Weinberg KI, Porteus MH. Efficient scarless genome editing in human pluripotent stem cells. Nature Methods. 15: 1045-1047. PMID 30504872 DOI: 10.1038/S41592-018-0212-Y  0.766
2018 Yamamoto R, Wilkinson AC, Nakauchi H. Changing concepts in hematopoietic stem cells. Science (New York, N.Y.). 362: 895-896. PMID 30467158 DOI: 10.1126/Science.Aat7873  0.479
2018 van Galen P, Mbong N, Kreso A, Schoof EM, Wagenblast E, Ng SWK, Krivdova G, Jin L, Nakauchi H, Dick JE. Integrated Stress Response Activity Marks Stem Cells in Normal Hematopoiesis and Leukemia. Cell Reports. 25: 1109-1117.e5. PMID 30380403 DOI: 10.1016/J.Celrep.2018.10.021  0.468
2018 Taoka K, Arai S, Kataoka K, Hosoi M, Miyauchi M, Yamazaki S, Honda A, Aixinjueluo W, Kobayashi T, Kumano K, Yoshimi A, Otsu M, Niwa A, Nakahata T, Nakauchi H, et al. Using patient-derived iPSCs to develop humanized mouse models for chronic myelomonocytic leukemia and therapeutic drug identification, including liposomal clodronate. Scientific Reports. 8: 15855. PMID 30367142 DOI: 10.1038/S41598-018-34193-1  0.414
2018 Yamaguchi T, Sato H, Kobayashi T, Kato-Itoh M, Goto T, Hara H, Mizuno N, Yanagida A, Umino A, Hamanaka S, Suchy F, Masaki H, Ota Y, Hirabayashi M, Nakauchi H. An interspecies barrier to tetraploid complementation and chimera formation. Scientific Reports. 8: 15289. PMID 30327488 DOI: 10.1038/S41598-018-33690-7  0.333
2018 Hamanaka S, Umino A, Sato H, Hayama T, Yanagida A, Mizuno N, Kobayashi T, Kasai M, Suchy FP, Yamazaki S, Masaki H, Yamaguchi T, Nakauchi H. Generation of Vascular Endothelial Cells and Hematopoietic Cells by Blastocyst Complementation. Stem Cell Reports. PMID 30245211 DOI: 10.1016/J.Stemcr.2018.08.015  0.393
2018 Ng SS, Saeb-Parsy K, Blackford SJI, Segal JM, Serra MP, Horcas-Lopez M, No DY, Mastoridis S, Jassem W, Frank CW, Cho NJ, Nakauchi H, Glenn JS, Rashid ST. Human iPS derived progenitors bioengineered into liver organoids using an inverted colloidal crystal poly (ethylene glycol) scaffold. Biomaterials. 182: 299-311. PMID 30149262 DOI: 10.1016/J.Biomaterials.2018.07.043  0.413
2018 Higaki K, Hirao M, Kawana-Tachikawa A, Iriguchi S, Kumagai A, Ueda N, Bo W, Kamibayashi S, Watanabe A, Nakauchi H, Suzuki K, Kaneko S. Generation of HIV-Resistant Macrophages from IPSCs by Using Transcriptional Gene Silencing and Promoter-Targeted RNA. Molecular Therapy. Nucleic Acids. 12: 793-804. PMID 30141412 DOI: 10.1016/J.Omtn.2018.07.017  0.303
2018 Ando M, Nakauchi H, Komatsu N. [iPSC-derived rejuvenated T-cell therapy for Epstein-Barr virus-associated lymphomas]. [Rinsho Ketsueki] the Japanese Journal of Clinical Hematology. 59: 932-938. PMID 30078805 DOI: 10.11406/Rinketsu.59.932  0.335
2018 Oldani G, Peloso A, Vijgen S, Wilson EM, Slits F, Gex Q, Morel P, Delaune V, Orci LA, Yamaguchi T, Kobayashi T, Rubbia-Brandt L, Nakauchi H, Lacotte S, Toso C. Chimeric liver transplantation reveals interspecific graft remodelling. Journal of Hepatology. PMID 30031887 DOI: 10.1016/J.Jhep.2018.07.008  0.31
2018 Ishizuka S, Lai CY, Otsu M, Nakauchi H, Nagamune T, Kawahara M. Designing motif-engineered receptors to elucidate signaling molecules important for proliferation of hematopoietic stem cells. Acs Synthetic Biology. PMID 29920201 DOI: 10.1021/Acssynbio.8B00163  0.462
2018 Tadokoro Y, Hoshii T, Yamazaki S, Eto K, Ema H, Kobayashi M, Ueno M, Ohta K, Arai Y, Hara E, Harada K, Oshima M, Oshima H, Arai F, Yoshimura A, ... Nakauchi H, et al. Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress. Cell Stem Cell. 22: 713-725.e8. PMID 29706577 DOI: 10.1016/J.Stem.2018.04.002  0.376
2018 Wilkinson AC, Morita M, Nakauchi H, Yamazaki S. Branched-chain amino acid depletion conditions bone marrow for hematopoietic stem cell transplantation avoiding amino acid imbalance-associated toxicity. Experimental Hematology. PMID 29705267 DOI: 10.1016/J.Exphem.2018.04.004  0.386
2018 Yamamoto R, Wilkinson AC, Ooehara J, Lan X, Lai CY, Nakauchi Y, Pritchard JK, Nakauchi H. Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment. Cell Stem Cell. 22: 600-607.e4. PMID 29625072 DOI: 10.1016/J.Stem.2018.03.013  0.464
2018 Yoshida A, Lee JK, Tomoyama S, Miwa K, Shirakawa K, Hamanaka S, Yamaguchi T, Nakauchi H, Miyagawa S, Sawa Y, Komuro I, Sakata Y. In vitro platform of allogeneic stem cell-derived cardiomyocyte transplantation for cardiac conduction defects. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. PMID 29554331 DOI: 10.1093/Europace/Eux379  0.436
2018 Ong J, Serra MP, Segal J, Cujba AM, Ng SS, Butler R, Millar V, Hatch S, Zimri S, Koike H, Chan K, Bonham A, Walk M, Voss T, Heaton N, ... ... Nakauchi H, et al. Imaging-Based Screen Identifies Laminin 411 as a Physiologically Relevant Niche Factor with Importance for i-Hep Applications. Stem Cell Reports. PMID 29478892 DOI: 10.1016/J.Stemcr.2018.01.025  0.446
2018 Matsunari H, Watanabe M, Nakano K, Enosawa S, Umeyama K, Uchikura A, Yashima S, Fukuda T, Klymiuk N, Kurome M, Kessler B, Wuensch A, Zakhartchenko V, Wolf E, Hanazono Y, ... ... Nakauchi H, et al. Modeling lethal X-linked genetic disorders in pigs with ensured fertility. Proceedings of the National Academy of Sciences of the United States of America. PMID 29311328 DOI: 10.1073/Pnas.1715940115  0.346
2018 Suchy F, Yamaguchi T, Nakauchi H. iPSC-Derived Organs In Vivo: Challenges and Promise. Cell Stem Cell. 22: 21-24. PMID 29304339 DOI: 10.1016/J.Stem.2017.12.003  0.322
2017 Aihara A, Koike T, Abe N, Nakamura S, Sawaguchi A, Nakamura T, Sugimoto N, Nakauchi H, Nishino T, Eto K. Novel TPO receptor agonist TA-316 contributes to platelet biogenesis from human iPS cells. Blood Advances. 1: 468-476. PMID 29296963 DOI: 10.1182/Bloodadvances.2016000844  0.445
2017 Vilarino M, Rashid ST, Suchy FP, McNabb BR, van der Meulen T, Fine EJ, Ahsan S, Mursaliyev N, Sebastiano V, Diab SS, Huising MO, Nakauchi H, Ross PJ. CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep. Scientific Reports. 7: 17472. PMID 29234093 DOI: 10.1038/S41598-017-17805-0  0.348
2017 Kon A, Yamazaki S, Nannya Y, Kataoka K, Ota Y, Nakagawa MM, Yoshida K, Shiozawa Y, Morita M, Yoshizato T, Sanada M, Nakayama M, Koseki H, Nakauchi H, Ogawa S. Physiological Srsf2 P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice. Blood. PMID 29146882 DOI: 10.1182/Blood-2017-01-762393  0.432
2017 Yang J, Ryan DJ, Wang W, Tsang JC, Lan G, Masaki H, Gao X, Antunes L, Yu Y, Zhu Z, Wang J, Kolodziejczyk AA, Campos LS, Wang C, Yang F, ... ... Nakauchi H, et al. Establishment of mouse expanded potential stem cells. Nature. PMID 29019987 DOI: 10.1038/Nature24052  0.537
2017 Ren Y, Sekine-Kondo E, Shibata R, Kato-Itoh M, Umino A, Yanagida A, Satoh M, Inoue K, Yamaguchi T, Mochida K, Nakae S, Van Kaer L, Iwabuchi K, Nakauchi H, Watarai H. A Novel Mouse Model of iNKT Cell-deficiency Generated by CRISPR/Cas9 Reveals a Pathogenic Role of iNKT Cells in Metabolic Disease. Scientific Reports. 7: 12765. PMID 28986544 DOI: 10.1038/S41598-017-12475-4  0.439
2017 Saka K, Lai CY, Nojima M, Kawahara M, Otsu M, Nakauchi H, Nagamune T. Dissection of Signaling Events Downstream of the c-Mpl Receptor in Murine Hematopoietic Stem Cells Via Motif-Engineered Chimeric Receptors. Stem Cell Reviews. PMID 28948469 DOI: 10.1007/S12015-017-9768-7  0.422
2017 Tsukada M, Ota Y, Wilkinson AC, Becker HJ, Osato M, Nakauchi H, Yamazaki S. In Vivo Generation of Engraftable Murine Hematopoietic Stem Cells by Gfi1b, c-Fos, and Gata2 Overexpression within Teratoma. Stem Cell Reports. PMID 28943250 DOI: 10.1016/J.Stemcr.2017.08.010  0.493
2017 Tachikawa S, Nishimura T, Nakauchi H, Ohnuma K. Thalidomide induces apoptosis in undifferentiated human induced pluripotent stem cells. In Vitro Cellular & Developmental Biology. Animal. 53: 841-851. PMID 28849348 DOI: 10.1007/S11626-017-0192-8  0.788
2017 Hirabayashi M, Hara H, Goto T, Takizawa A, Dwinell MR, Yamanaka T, Hochi S, Nakauchi H. Haploid embryonic stem cell lines derived from androgenetic and parthenogenetic rat blastocysts. The Journal of Reproduction and Development. 63: 611-616. PMID 28824040 DOI: 10.1262/Jrd.2017-074  0.457
2017 Suchy F, Nakauchi H. Lessons from Interspecies Mammalian Chimeras. Annual Review of Cell and Developmental Biology. 33: 203-217. PMID 28806099 DOI: 10.1146/Annurev-Cellbio-100616-060654  0.417
2017 Masaki H, Nakauchi H. Interspecies chimeras for human stem cell research. Development (Cambridge, England). 144: 2544-2547. PMID 28720651 DOI: 10.1242/Dev.151183  0.483
2017 Ueno K, Iwagawa T, Ochiai G, Koso H, Nakauchi H, Nagasaki M, Suzuki Y, Watanabe S. Analysis of Müller glia specific genes and their histone modification using Hes1-promoter driven EGFP expressing mouse. Scientific Reports. 7: 3578. PMID 28620206 DOI: 10.1038/S41598-017-03874-8  0.375
2017 Itakura G, Kawabata S, Ando M, Nishiyama Y, Sugai K, Ozaki M, Iida T, Ookubo T, Kojima K, Kashiwagi R, Yasutake K, Nakauchi H, Miyoshi H, Nagoshi N, Kohyama J, et al. Fail-Safe System against Potential Tumorigenicity after Transplantation of iPSC Derivatives. Stem Cell Reports. PMID 28262544 DOI: 10.1016/J.Stemcr.2017.02.003  0.484
2017 Ieyasu A, Ishida R, Kimura T, Morita M, Wilkinson AC, Sudo K, Nishimura T, Ohehara J, Tajima Y, Lai CY, Otsu M, Nakamura Y, Ema H, Nakauchi H, Yamazaki S. An All-Recombinant Protein-Based Culture System Specifically Identifies Hematopoietic Stem Cell Maintenance Factors. Stem Cell Reports. PMID 28238792 DOI: 10.1016/J.Stemcr.2017.01.015  0.779
2017 Yamaguchi T, Sato H, Kato-Itoh M, Goto T, Hara H, Sanbo M, Mizuno N, Kobayashi T, Yanagida A, Umino A, Ota Y, Hamanaka S, Masaki H, Rashid ST, Hirabayashi M, ... Nakauchi H, et al. Interspecies organogenesis generates autologous functional islets. Nature. PMID 28117444 DOI: 10.1038/Nature21070  0.362
2017 Tajima Y, Ito K, Umino A, Wilkinson AC, Nakauchi H, Yamazaki S. Continuous cell supply from Krt7-expressing hematopoietic stem cells during native hematopoiesis revealed by targeted in vivo gene transfer method. Scientific Reports. 7: 40684. PMID 28098173 DOI: 10.1038/Srep40684  0.531
2017 Ando M, Nakauchi H. 'Off-the-shelf' immunotherapy with iPSC-derived rejuvenated cytotoxic T lymphocytes. Experimental Hematology. 47: 2-12. PMID 27826124 DOI: 10.1016/J.Exphem.2016.10.009  0.424
2017 Wilkinson A, Taya Y, Yamazaki S, Nakauchi H. Dissecting the valine dependency of hematopoietic stem cell function Experimental Hematology. 53. DOI: 10.1016/J.Exphem.2017.06.095  0.494
2016 Taya Y, Ota Y, Wilkinson AC, Kanazawa A, Watarai H, Kasai M, Nakauchi H, Yamazaki S. Depleting dietary valine permits nonmyeloablative mouse hematopoietic stem cell transplantation. Science (New York, N.Y.). 354: 1152-1155. PMID 27934766 DOI: 10.1126/Science.Aag3145  0.463
2016 Tarusawa E, Sanbo M, Okayama A, Miyashita T, Kitsukawa T, Hirayama T, Hirabayashi T, Hasegawa S, Kaneko R, Toyoda S, Kobayashi T, Kato-Itoh M, Nakauchi H, Hirabayashi M, Yagi T, et al. Establishment of high reciprocal connectivity between clonal cortical neurons is regulated by the Dnmt3b DNA methyltransferase and clustered protocadherins. Bmc Biology. 14: 103. PMID 27912755 DOI: 10.1186/S12915-016-0326-6  0.33
2016 Wu J, Greely HT, Jaenisch R, Nakauchi H, Rossant J, Belmonte JC. Stem cells and interspecies chimaeras. Nature. 540: 51-59. PMID 27905428 DOI: 10.1038/Nature20573  0.47
2016 Masaki H, Kato-Itoh M, Takahashi Y, Umino A, Sato H, Ito K, Yanagida A, Nishimura T, Yamaguchi T, Hirabayashi M, Era T, Loh KM, Wu SM, Weissman IL, Nakauchi H. Inhibition of Apoptosis Overcomes Stage-Related Compatibility Barriers to Chimera Formation in Mouse Embryos. Cell Stem Cell. 19: 587-592. PMID 27814480 DOI: 10.1016/J.Stem.2016.10.013  0.763
2016 Lin HT, Okumura T, Yatsuda Y, Ito S, Nakauchi H, Otsu M. Application of Droplet Digital PCR for Estimating Vector Copy Number States in Stem Cell Gene Therapy. Human Gene Therapy Methods. 27: 197-208. PMID 27763786 DOI: 10.1089/Hgtb.2016.059  0.408
2016 Ishida T, Suzuki S, Lai CY, Yamazaki S, Kakuta S, Iwakura Y, Nojima M, Takeuchi Y, Higashihara M, Nakauchi H, Otsu M. Pre-transplantation blockade of TNF-α-mediated oxygen species accumulation protects hematopoietic stem cells. Stem Cells (Dayton, Ohio). PMID 27753160 DOI: 10.1002/Stem.2524  0.4
2016 Yokoi T, Yokoi K, Akiyama K, Higuchi T, Shimada Y, Kobayashi H, Sato T, Ohteki T, Otsu M, Nakauchi H, Ida H, Ohashi T. Non-myeloablative preconditioning with ACK2 (anti-c-kit antibody) is efficient in bone marrow transplantation for murine models of mucopolysaccharidosis type II. Molecular Genetics and Metabolism. PMID 27590924 DOI: 10.1016/J.Ymgme.2016.08.003  0.322
2016 Ishida T, Takahashi S, Lai CY, Nojima M, Yamamoto R, Takeuchi E, Takeuchi Y, Higashihara M, Nakauchi H, Otsu M. Multiple allogeneic progenitors in combination function as a unit to support early transient hematopoiesis in transplantation. The Journal of Experimental Medicine. PMID 27503070 DOI: 10.1084/Jem.20151493  0.437
2016 Durruthy-Durruthy J, Wossidlo M, Pai S, Takahashi Y, Kang G, Omberg L, Chen B, Nakauchi H, Reijo Pera R, Sebastiano V. Spatiotemporal Reconstruction of the Human Blastocyst by Single-Cell Gene-Expression Analysis Informs Induction of Naive Pluripotency. Developmental Cell. 38: 100-115. PMID 27404362 DOI: 10.1016/J.Devcel.2016.06.014  0.479
2016 Kaneko S, Kakinuma S, Asahina Y, Kamiya A, Miyoshi M, Tsunoda T, Nitta S, Asano Y, Nagata H, Otani S, Kawai-Kitahata F, Murakawa M, Itsui Y, Nakagawa M, Azuma S, ... Nakauchi H, et al. Human induced pluripotent stem cell-derived hepatic cell lines as a new model for host interaction with hepatitis B virus. Scientific Reports. 6: 29358. PMID 27386799 DOI: 10.1038/Srep29358  0.381
2016 Ueno K, Iwagawa T, Kuribayashi H, Baba Y, Nakauchi H, Murakami A, Nagasaki M, Suzuki Y, Watanabe S. Transition of differential histone H3 methylation in photoreceptors and other retinal cells during retinal differentiation. Scientific Reports. 6: 29264. PMID 27377164 DOI: 10.1038/Srep29264  0.392
2016 Koide S, Oshima M, Takubo K, Yamazaki S, Nitta E, Saraya A, Aoyama K, Kato Y, Miyagi S, Nakajima-Takagi Y, Chiba T, Matsui H, Arai F, Suzuki Y, Kimura H, ... Nakauchi H, et al. Setdb1 maintains hematopoietic stem and progenitor cells by restricting the ectopic activation of non-hematopoietic genes. Blood. PMID 27301860 DOI: 10.1182/Blood-2016-01-694810  0.518
2016 Dhahri D, Sato-Kusubata K, Ohki-Koizumi M, Nishida C, Tashiro Y, Munakata S, Shimazu H, Salama Y, Eiamboonsert S, Nakauchi H, Hattori K, Heissig B. Fibrinolytic factor-mediated crosstalk with endothelial cells expands murine bone marrow mesenchymal stromal cells. Blood. PMID 27283026 DOI: 10.1182/Blood-2015-10-673103  0.436
2016 Hayama T, Yamaguchi T, Kato-Itoh M, Ishii Y, Mizuno N, Umino A, Sato H, Sanbo M, Hamanaka S, Masaki H, Hirabayashi M, Nakauchi H. Practical selection methods for rat and mouse round spermatids without DNA staining by flow cytometric cell sorting. Molecular Reproduction and Development. PMID 27031189 DOI: 10.1002/Mrd.22644  0.334
2016 Hara H, Goto T, Takizawa A, Sanbo M, Jacob HJ, Kobayashi T, Nakauchi H, Hochi S, Hirabayashi M. Rat Blastocysts from Nuclear Injection and Time-Lagged Enucleation and Their Commitment to Embryonic Stem Cells. Cellular Reprogramming. 18: 108-15. PMID 26990947 DOI: 10.1089/cell.2015.0084  0.321
2016 Goto T, Hara H, Nakauchi H, Hochi S, Hirabayashi M. Hypomorphic phenotype of Foxn1 gene-modified rats by CRISPR/Cas9 system. Transgenic Research. 25: 533-44. PMID 26931321 DOI: 10.1007/S11248-016-9941-9  0.314
2016 Chen JY, Miyanishi M, Wang SK, Yamazaki S, Sinha R, Kao KS, Seita J, Sahoo D, Nakauchi H, Weissman IL. Hoxb5 marks long-term haematopoietic stem cells and reveals a homogenous perivascular niche. Nature. 530: 223-7. PMID 26863982 DOI: 10.1038/Nature16943  0.488
2016 Tsukada M, Yamazaki S, Ota Y, Nakauchi H. In Vivo Generation of Engraftable Murine Hematopoietic Stem Cells from Induced Pluripotent Stem Cells through Hemogenic Endothelium Blood. 128: 3866-3866. DOI: 10.1182/Blood.V128.22.3866.3866  0.513
2016 Ishigaki T, Taya Y, Yamazaki S, Kobayashi S, Ohno N, Uchimaru K, Tojo A, Nakauchi H. Proof of Merit in New Diet Therapy Against Adult T-Cell Leukemia/Lymphoma: Applying Specific Amino Acid Dependency of Leukemia/Lymphoma Cells Blood. 128: 1765-1765. DOI: 10.1182/Blood.V128.22.1765.1765  0.453
2016 Yamamoto R, Ooeahra J, Nakauchi H. Clonal analysis in vivo unveils atypical dynamics of aged hematopoietic stem cells Experimental Hematology. 44. DOI: 10.1016/J.Exphem.2016.06.102  0.446
2015 Ghosn EE, Waters J, Phillips M, Yamamoto R, Long BR, Yang Y, Gerstein R, Stoddart CA, Nakauchi H, Herzenberg LA. Fetal Hematopoietic Stem Cell Transplantation Fails to Fully Regenerate the B-Lymphocyte Compartment. Stem Cell Reports. PMID 26724903 DOI: 10.1016/J.Stemcr.2015.11.011  0.39
2015 Otani S, Kakinuma S, Kamiya A, Goto F, Kaneko S, Miyoshi M, Tsunoda T, Asano Y, Kawai-Kitahata F, Nitta S, Nakata T, Okamoto R, Itsui Y, Nakagawa M, Azuma S, ... ... Nakauchi H, et al. Matrix Metalloproteinase-14 Mediates Formation of Bile Ducts and Hepatic Maturation of Fetal Hepatic Progenitor Cells. Biochemical and Biophysical Research Communications. PMID 26724533 DOI: 10.1016/J.Bbrc.2015.12.105  0.308
2015 Lin HT, Masaki H, Yamaguchi T, Wada T, Yachie A, Nishimura K, Ohtaka M, Nakanishi M, Nakauchi H, Otsu M. An assessment of the effects of ectopic gp91phox expression in XCGD iPSC-derived neutrophils. Molecular Therapy. Methods & Clinical Development. 2: 15046. PMID 26682238 DOI: 10.1038/Mtm.2015.46  0.456
2015 Yanagida A, Mizuno N, Yamazaki Y, Kato-Itoh M, Umino A, Sato H, Ito K, Yamaguchi T, Nakauchi H, Kamiya A. Investigation of bi-potent differentiation of hepatoblasts using inducible diphtheria toxin receptor-transgenic mice. Hepatology Research : the Official Journal of the Japan Society of Hepatology. PMID 26584962 DOI: 10.1111/Hepr.12622  0.406
2015 Sharma A, Sebastiano V, Scott CT, Magnus D, Koyano-Nakagawa N, Garry DJ, Witte ON, Nakauchi H, Wu JC, Weissman IL, Wu SM. Lift NIH restrictions on chimera research. Science (New York, N.Y.). 350: 640. PMID 26542560 DOI: 10.1126/Science.350.6261.640-A  0.417
2015 Miyamoto T, Nakauchi H. [Generation of functional organs from pluripotent stem cells]. [Rinshō Ketsueki] the Japanese Journal of Clinical Hematology. 56: 2213-9. PMID 26458462 DOI: 10.11406/Rinketsu.56.2213  0.483
2015 Chikada H, Ito K, Yanagida A, Nakauchi H, Kamiya A. The basic helix-loop-helix transcription factor, Mist1, induces maturation of mouse fetal hepatoblasts. Scientific Reports. 5: 14989. PMID 26456005 DOI: 10.1038/Srep14989  0.385
2015 Ando M, Nishimura T, Yamazaki S, Yamaguchi T, Kawana-Tachikawa A, Hayama T, Nakauchi Y, Ando J, Ota Y, Takahashi S, Nishimura K, Ohtaka M, Nakanishi M, Miles JJ, Burrows SR, ... ... Nakauchi H, et al. A Safeguard System for Induced Pluripotent Stem Cell-Derived Rejuvenated T Cell Therapy. Stem Cell Reports. PMID 26321144 DOI: 10.1016/J.Stemcr.2015.07.011  0.749
2015 Naka K, Jomen Y, Ishihara K, Kim J, Ishimoto T, Bae EJ, Mohney RP, Stirdivant SM, Oshima H, Oshima M, Kim DW, Nakauchi H, Takihara Y, Kato Y, Ooshima A, et al. Dipeptide species regulate p38MAPK-Smad3 signalling to maintain chronic myelogenous leukaemia stem cells. Nature Communications. 6: 8039. PMID 26289811 DOI: 10.1038/Ncomms9039  0.505
2015 Yanagida A, Chikada H, Ito K, Umino A, Kato-Itoh M, Yamazaki Y, Sato H, Kobayashi T, Yamaguchi T, Nakayama KI, Nakauchi H, Kamiya A. Liver maturation deficiency in p57(Kip2)-/- mice occurs in a hepatocytic p57(Kip2) expression-independent manner. Developmental Biology. PMID 26165599 DOI: 10.1016/J.Ydbio.2015.07.004  0.414
2015 Saito T, Yano F, Mori D, Kawata M, Hoshi K, Takato T, Masaki H, Otsu M, Eto K, Nakauchi H, Chung UI, Tanaka S. Hyaline cartilage formation and tumorigenesis of implanted tissues derived from human induced pluripotent stem cells Biomedical Research (Japan). 36: 179-186. PMID 26106047 DOI: 10.2220/Biomedres.36.179  0.474
2015 Masaki H, Kato-Itoh M, Umino A, Sato H, Hamanaka S, Kobayashi T, Yamaguchi T, Nishimura K, Ohtaka M, Nakanishi M, Nakauchi H. Interspecific in vitro assay for the chimera-forming ability of human pluripotent stem cells. Development (Cambridge, England). 142: 3222-30. PMID 26023098 DOI: 10.1242/Dev.124016  0.397
2015 Takeuchi Y, Takeuchi E, Ishida T, Onodera M, Nakauchi H, Otsu M. Curative haploidentical BMT in a murine model of X-linked chronic granulomatous disease. International Journal of Hematology. 102: 111-20. PMID 25921405 DOI: 10.1007/S12185-015-1799-8  0.374
2015 Okeyo KO, Kurosawa O, Yamazaki S, Oana H, Kotera H, Nakauchi H, Washizu M. Cell Adhesion Minimization by a Novel Mesh Culture Method Mechanically Directs Trophoblast Differentiation and Self-Assembly Organization of Human Pluripotent Stem Cells. Tissue Engineering. Part C, Methods. 21: 1105-15. PMID 25914965 DOI: 10.1089/ten.TEC.2015.0038  0.391
2015 Takebe T, Enomura M, Yoshizawa E, Kimura M, Koike H, Ueno Y, Matsuzaki T, Yamazaki T, Toyohara T, Osafune K, Nakauchi H, Yoshikawa HY, Taniguchi H. Vascularized and Complex Organ Buds from Diverse Tissues via Mesenchymal Cell-Driven Condensation. Cell Stem Cell. 16: 556-65. PMID 25891906 DOI: 10.1016/J.Stem.2015.03.004  0.387
2015 Yamamoto S, Otsu M, Matsuzaka E, Konishi C, Takagi H, Hanada S, Mochizuki S, Nakauchi H, Imai K, Tsuji K, Ebihara Y. Screening of drugs to treat 8p11 myeloproliferative syndrome using patient-derived induced pluripotent stem cells with fusion gene CEP110-FGFR1. Plos One. 10: e0120841. PMID 25803811 DOI: 10.1371/Journal.Pone.0120841  0.519
2015 Toriumi T, Takayama N, Murakami M, Sato M, Yuguchi M, Yamazaki Y, Eto K, Otsu M, Nakauchi H, Shirakawa T, Isokawa K, Honda MJ. Characterization of mesenchymal progenitor cells in the crown and root pulp of primary teeth. Biomedical Research (Tokyo, Japan). 36: 31-45. PMID 25749149 DOI: 10.2220/Biomedres.36.31  0.527
2015 Yanagida A, Nakauchi H, Kamiya A. Generation and In Vitro Expansion of Hepatic Progenitor Cells from Human iPS Cells. Methods in Molecular Biology (Clifton, N.J.). PMID 25697415 DOI: 10.1007/7651_2015_199  0.509
2015 Murayama H, Masaki H, Sato H, Hayama T, Yamaguchi T, Nakauchi H. Successful reprogramming of epiblast stem cells by blocking nuclear localization of β-catenin. Stem Cell Reports. 4: 103-13. PMID 25556568 DOI: 10.1016/J.Stemcr.2014.12.003  0.454
2015 Yokoi K, Akiyama K, Kaneshiro E, Higuchi T, Shimada Y, Kobayashi H, Akiyama M, Otsu M, Nakauchi H, Ohashi T, Ida H. Effect of donor chimerism to reduce the level of glycosaminoglycans following bone marrow transplantation in a murine model of mucopolysaccharidosis type II. Journal of Inherited Metabolic Disease. 38: 333-40. PMID 25503568 DOI: 10.1007/S10545-014-9800-X  0.346
2015 Nakauchi Y, Yamazaki S, Napier SC, Usui J, Ota Y, Takahashi S, Watanabe N, Nakauchi H. Effective treatment against severe graft-versus-host disease with allele-specific anti-HLA monoclonal antibody in a humanized mouse model. Experimental Hematology. 43: 79-88.e1-4. PMID 25448490 DOI: 10.1016/J.Exphem.2014.10.008  0.426
2015 Wu JM, Hsueh YC, Ch'ang HJ, Luo CY, Wu LW, Nakauchi H, Hsieh PC. Circulating cells contribute to cardiomyocyte regeneration after injury. Circulation Research. 116: 633-41. PMID 25398235 DOI: 10.1161/Circresaha.116.304564  0.361
2015 Iriguchi S, Kikuchi N, Kaneko S, Noguchi E, Morishima Y, Matsuyama M, Yoh K, Takahashi S, Nakauchi H, Ishii Y. T-cell-restricted T-bet overexpression induces aberrant hematopoiesis of myeloid cells and impairs function of macrophages in the lung. Blood. 125: 370-82. PMID 25349175 DOI: 10.1182/Blood-2014-05-575225  0.334
2015 Kobayashi T, Kato-Itoh M, Nakauchi H. Targeted organ generation using Mixl1-inducible mouse pluripotent stem cells in blastocyst complementation. Stem Cells and Development. 24: 182-9. PMID 25192056 DOI: 10.1089/scd.2014.0270  0.372
2015 Rashid T, Takebe T, Nakauchi H. Novel strategies for liver therapy using stem cells. Gut. 64: 1-4. PMID 25183202 DOI: 10.1136/Gutjnl-2014-307480  0.357
2015 Ishigaki T, Zaike Y, Nojima M, Kobayashi S, Ohno N, Uchimaru K, Tojo A, Nakauchi H, Watanabe N. Quantification of adult T-cell leukemia/lymphoma cells using simple four-color flow cytometry. Clinical Chemistry and Laboratory Medicine : Cclm / Fescc. 53: 85-93. PMID 25060346 DOI: 10.1515/Cclm-2014-0183  0.421
2015 Ishida T, Takahashi S, Lai C, Higashihara M, Nakauchi H, Otsu M. Proof of Benefit in Multiple-Cord Blood Transplantation Evidenced By Early Hematopoietic Reconstitution Blood. 126: 3071-3071. DOI: 10.1182/Blood.V126.23.3071.3071  0.459
2015 Ishida T, Suzuki S, Lai C, Higashihara M, Nakauchi H, Otsu M. Protection of Transplanted Hematopoietic Stem Cells from Inflammatory Recipient Marrow Environment through Specific TNF-α Signal Blockade Blood. 126: 1867-1867. DOI: 10.1182/Blood.V126.23.1867.1867  0.378
2015 Kon A, Yamazaki S, Ota Y, Kataoka K, Shiozawa Y, Morita M, Yoshizato T, Sanada M, Yoshida K, Nakayama M, Koseki H, Nakauchi H, Ogawa S. Srsf2 P95H Mutation Causes Impaired Stem Cell Repopulation and Hematopoietic Differentiation in Mice Blood. 126: 1649-1649. DOI: 10.1182/Blood.V126.23.1649.1649  0.419
2015 Okeyo KO, Kurosawa O, Yamazaki S, Oana H, Kotera H, Nakauchi H, Washizu M. Cell Adhesion Minimization by a Novel Mesh Culture Method Mechanically Directs Trophoblast Differentiation and Self-Assembly Organization of Human Pluripotent Stem Cells Tissue Engineering - Part C: Methods. 21: 1105-1115. DOI: 10.1089/ten.tec.2015.0038  0.349
2015 Uchikura A, Matsunari H, Nakano K, Hatae S, Matsumura Y, Asano Y, Takeishi T, Nakauchi H, Nagashima H. 73 Application Of The Hollow Fiber Vitrification Method To The Cryopreservation Of Highly Cryosensitive Embryos Reproduction, Fertility and Development. 27: 129-130. DOI: 10.1071/Rdv27N1Ab73  0.314
2015 Matsunari H, Watanabe M, Nakano K, Uchikura A, Asano Y, Hatae S, Takeishi T, Umeyama K, Nagaya M, Miyagawa S, Hanazono Y, Nakauchi H, Nagashima H. 31 Production Efficiency Of Gene Knockout Pigs Using Genome Editing And Somatic Cell Cloning Reproduction, Fertility and Development. 27: 108-108. DOI: 10.1071/Rdv27N1Ab31  0.45
2015 Ando M, Nishimura T, Yamazaki S, Yamaguchi T, Kawana-Tachikawa A, Hayama T, Nakauchi Y, Ando J, Ota Y, Takahashi S, Nishimura K, Ohtaka M, Nakanishi M, Miles JJ, Burrows SR, ... ... Nakauchi H, et al. A Safeguard System for Induced Pluripotent Stem Cell-Derived Rejuvenated T Cell Therapy Stem Cell Reports. DOI: 10.1016/j.stemcr.2015.07.011  0.777
2015 Yamazaki S, Nakauchi H. Specific amino acid environments of bone marrow are crucial for the maintenance of hematopoietic stem cells Experimental Hematology. 43. DOI: 10.1016/J.Exphem.2015.06.284  0.409
2015 Tajima Y, Yamazaki S, Nakauchi H. A new gene transfer system for hematopoietic stem cells under physiological condition Experimental Hematology. 43. DOI: 10.1016/J.Exphem.2015.06.262  0.442
2015 Tadokoro Y, Yoshimura A, Nakauchi H, Hirao A. Role of spred1 in the regulation of self-renewal and aging of hematopoietic stem cells Experimental Hematology. 43. DOI: 10.1016/J.Exphem.2015.06.259  0.424
2015 Sudo K, Yamazaki S, Nakauchi H, Nakamura Y. Maintenance and expansion of human hematopoietic stem and progenitor cells in the presence of defined factors alone Experimental Hematology. 43. DOI: 10.1016/J.Exphem.2015.06.257  0.503
2015 Iriguchi S, Kikuchi N, Noguchi E, Morishima Y, Matsuyama M, Yoh K, Takahashi S, Nakauchi H, Ishii Y, Kaneko S. T cell-restricted T-bet overexpression induces aberrant hematopoiesis of myeloid cells and impairs function of lung macrophages in the lung Experimental Hematology. 43. DOI: 10.1016/J.Exphem.2015.06.148  0.332
2015 Ieyasu A, Yamazaki S, Nakauchi H. Homeostatic regulation of hematopoietic stem cells by the interaction of niche factors Experimental Hematology. 43. DOI: 10.1016/J.Exphem.2015.06.145  0.459
2015 Nakauchi H. Dietary created niche for non-myeloablative hematopoietic stem cell transplantation Experimental Hematology. 43. DOI: 10.1016/J.Exphem.2015.06.030  0.461
2014 Iida A, Iwagawa T, Baba Y, Satoh S, Mochizuki1 Y, Nakauchi H, Furukawa T, Koseki H, Murakami A, Watanabe S. Roles of histone H3K27 trimethylase Ezh2 in retinal proliferation and differentiation. Developmental Neurobiology. PMID 25556712 DOI: 10.1002/Dneu.22261  0.367
2014 Abdul Razak SR, Baba Y, Nakauchi H, Otsu M, Watanabe S. DNA Methylation Is Involved in the Expression of miR-142-3p in Fibroblasts and Induced Pluripotent Stem Cells. Stem Cells International. 2014: 101349. PMID 25544846 DOI: 10.1155/2014/101349  0.35
2014 Ito T, Sendai Y, Yamazaki S, Seki-Soma M, Hirose K, Watanabe M, Fukawa K, Nakauchi H. Generation of recombination activating gene-1-deficient neonatal piglets: a model of T and B cell deficient severe combined immune deficiency. Plos One. 9: e113833. PMID 25437445 DOI: 10.1371/Journal.Pone.0113833  0.444
2014 Rashid T, Kobayashi T, Nakauchi H. Revisiting the flight of Icarus: making human organs from PSCs with large animal chimeras. Cell Stem Cell. 15: 406-9. PMID 25280216 DOI: 10.1016/J.Stem.2014.09.013  0.38
2014 Yamaguchi T, Hamanaka S, Nakauchi H. The generation and maintenance of rat induced pluripotent stem cells. Methods of Molecular Biology. 1210: 143-150. PMID 25173166 DOI: 10.1007/978-1-4939-1435-7_11  0.418
2014 Hayama T, Yamaguchi T, Kato-Itoh M, Hamanaka S, Kawarai M, Sanbo M, Tamura C, Lee YS, Yanagida A, Murayama H, Mizuno N, Umino A, Sato H, Yamazaki S, Masaki H, ... ... Nakauchi H, et al. Generation of mouse functional oocytes in rat by xeno-ectopic transplantation of primordial germ cells. Biology of Reproduction. 91: 89. PMID 25165118 DOI: 10.1095/Biolreprod.114.121640  0.432
2014 Kazuki Y, Yakura Y, Abe S, Osaki M, Kajitani N, Kazuki K, Takehara S, Honma K, Suemori H, Yamazaki S, Sakuma T, Toki T, Shimizu R, Nakauchi H, Yamamoto T, et al. Down syndrome-associated haematopoiesis abnormalities created by chromosome transfer and genome editing technologies. Scientific Reports. 4: 6136. PMID 25159877 DOI: 10.1038/Srep06136  0.331
2014 Ito K, Yamazaki S, Yamamoto R, Tajima Y, Yanagida A, Kobayashi T, Kato-Itoh M, Kakuta S, Iwakura Y, Nakauchi H, Kamiya A. Gene targeting study reveals unexpected expression of brain-expressed X-linked 2 in endocrine and tissue stem/progenitor cells in mice. The Journal of Biological Chemistry. 289: 29892-911. PMID 25143383 DOI: 10.1074/Jbc.M114.580084  0.487
2014 Yamamoto R, Morita Y, Nakauchi H. Five-lineage clonal analysis of hematopoietic stem/progenitor cells. Methods in Molecular Biology (Clifton, N.J.). 1185: 237-45. PMID 25062633 DOI: 10.1007/978-1-4939-1133-2_16  0.503
2014 Kanke K, Masaki H, Saito T, Komiyama Y, Hojo H, Nakauchi H, Lichtler AC, Takato T, Chung UI, Ohba S. Stepwise differentiation of pluripotent stem cells into osteoblasts using four small molecules under serum-free and feeder-free conditions Stem Cell Reports. 2: 751-760. PMID 24936463 DOI: 10.1016/J.Stemcr.2014.04.016  0.5
2014 Ochi K, Takayama N, Hirose S, Nakahata T, Nakauchi H, Eto K. Multicolor Staining of Globin Subtypes Reveals Impaired Globin Switching During Erythropoiesis in Human Pluripotent Stem Cells Stem Cells Translational Medicine. 3: 792-800. PMID 24873860 DOI: 10.5966/Sctm.2013-0216  0.415
2014 Hosoi M, Kumano K, Taoka K, Arai S, Kataoka K, Ueda K, Kamikubo Y, Takayama N, Otsu M, Eto K, Nakauchi H, Kurokawa M. Generation of induced pluripotent stem cells derived from primary and secondary myelofibrosis patient samples. Experimental Hematology. 42: 816-25. PMID 24859480 DOI: 10.1016/J.Exphem.2014.03.010  0.495
2014 Yamazaki S, Nakauchi H. Bone marrow Schwann cells induce hematopoietic stem cell hibernation International Journal of Hematology. 99: 695-698. PMID 24817152 DOI: 10.1007/S12185-014-1588-9  0.486
2014 Seki M, Masaki H, Arauchi T, Nakauchi H, Sugano S, Suzuki Y. A comparison of the rest complex binding patterns in embryonic stem cells and epiblast stem cells. Plos One. 9. PMID 24752154 DOI: 10.1371/Journal.Pone.0095374  0.379
2014 Matsunari H, Kobayashi T, Watanabe M, Umeyama K, Nakano K, Kanai T, Matsuda T, Nagaya M, Hara M, Nakauchi H, Nagashima H. Transgenic pigs with pancreas-specific expression of green fluorescent protein. The Journal of Reproduction and Development. 60: 230-7. PMID 24748398 DOI: 10.1262/Jrd.2014-006  0.331
2014 Sakurai M, Kunimoto H, Watanabe N, Fukuchi Y, Yuasa S, Yamazaki S, Nishimura T, Sadahira K, Fukuda K, Okano H, Nakauchi H, Morita Y, Matsumura I, Kudo K, Ito E, et al. Impaired hematopoietic differentiation of RUNX1-mutated induced pluripotent stem cells derived from FPD/AML patients. Leukemia. 28: 2344-54. PMID 24732596 DOI: 10.1038/Leu.2014.136  0.768
2014 Toyoda S, Kawaguchi M, Kobayashi T, Tarusawa E, Toyama T, Okano M, Oda M, Nakauchi H, Yoshimura Y, Sanbo M, Hirabayashi M, Hirayama T, Hirabayashi T, Yagi T. Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity. Neuron. 82: 94-108. PMID 24698270 DOI: 10.1016/J.Neuron.2014.02.005  0.377
2014 Tsukiyama T, Kato-Itoh M, Nakauchi H, Ohinata Y. A comprehensive system for generation and evaluation of induced pluripotent stem cells using piggyBac transposition Plos One. 9. PMID 24667806 DOI: 10.1371/Journal.Pone.0092973  0.433
2014 Higuchi T, Kawagoe S, Otsu M, Shimada Y, Kobayashi H, Hirayama R, Eto K, Ida H, Ohashi T, Nakauchi H, Eto Y. The generation of induced pluripotent stem cells (iPSCs) from patients with infantile and late-onset types of Pompe disease and the effects of treatment with acid-α-glucosidase in Pompe's iPSCs. Molecular Genetics and Metabolism. 112: 44-8. PMID 24642446 DOI: 10.1016/J.Ymgme.2014.02.012  0.376
2014 Hirata N, Nakagawa M, Fujibayashi Y, Yamauchi K, Murata A, Minami I, Tomioka M, Kondo T, Kuo TF, Endo H, Inoue H, Sato S, Ando S, Kawazoe Y, Aiba K, ... ... Nakauchi H, et al. A chemical probe that labels human pluripotent stem cells. Cell Reports. 6: 1165-74. PMID 24613351 DOI: 10.1016/J.Celrep.2014.02.006  0.494
2014 Ieyasu A, Tajima Y, Shimba S, Nakauchi H, Yamazaki S. Clock gene Bmal1 is dispensable for intrinsic properties of murine hematopoietic stem cells. Journal of Negative Results in Biomedicine. 13: 4. PMID 24606809 DOI: 10.1186/1477-5751-13-4  0.422
2014 Iida A, Iwagawa T, Kuribayashi H, Satoh S, Mochizuki Y, Baba Y, Nakauchi H, Furukawa T, Koseki H, Murakami A, Watanabe S. Histone demethylase Jmjd3 is required for the development of subsets of retinal bipolar cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 3751-6. PMID 24572572 DOI: 10.1073/Pnas.1311480111  0.415
2014 Ishihara J, Umemoto T, Yamato M, Shiratsuchi Y, Takaki S, Petrich BG, Nakauchi H, Eto K, Kitamura T, Okano T. Nov/CCN3 regulates long-term repopulating activity of murine hematopoietic stem cells via integrin αvβ3 International Journal of Hematology. 99: 393-406. PMID 24563081 DOI: 10.1007/S12185-014-1534-X  0.451
2014 Matsunawa M, Yamamoto R, Sanada M, Sato-Otsubo A, Shiozawa Y, Yoshida K, Otsu M, Shiraishi Y, Miyano S, Isono K, Koseki H, Nakauchi H, Ogawa S. Haploinsufficiency of Sf3b1 leads to compromised stem cell function but not to myelodysplasia. Leukemia. 28: 1844-50. PMID 24535406 DOI: 10.1038/Leu.2014.73  0.49
2014 Nakamura S, Takayama N, Hirata S, Seo H, Endo H, Ochi K, Fujita K, Koike T, Harimoto K, Dohda T, Watanabe A, Okita K, Takahashi N, Sawaguchi A, Yamanaka S, ... Nakauchi H, et al. Expandable megakaryocyte cell lines enable clinically applicable generation of platelets from human induced pluripotent stem cells. Cell Stem Cell. 14: 535-48. PMID 24529595 DOI: 10.1016/J.Stem.2014.01.011  0.423
2014 Miyagi S, Koide S, Saraya A, Wendt GR, Oshima M, Konuma T, Yamazaki S, Mochizuki-Kashio M, Nakajima-Takagi Y, Wang C, Chiba T, Kitabayashi I, Nakauchi H, Iwama A. The TIF1β-HP1 system maintains transcriptional integrity of hematopoietic stem cells Stem Cell Reports. 2: 145-152. PMID 24527388 DOI: 10.1016/J.Stemcr.2013.12.008  0.481
2014 Lai CY, Yamazaki S, Okabe M, Suzuki S, Maeyama Y, Iimura Y, Onodera M, Kakuta S, Iwakura Y, Nojima M, Otsu M, Nakauchi H. Stage-specific roles for CXCR4 signaling in murine hematopoietic stem/progenitor cells in the process of bone marrow repopulation. Stem Cells (Dayton, Ohio). 32: 1929-42. PMID 24510783 DOI: 10.1002/Stem.1670  0.47
2014 Ariki R, Morikawa S, Mabuchi Y, Suzuki S, Nakatake M, Yoshioka K, Hidano S, Nakauchi H, Matsuzaki Y, Nakamura T, Goitsuka R. Homeodomain transcription factor Meis1 is a critical regulator of adult bone marrow hematopoiesis. Plos One. 9: e87646. PMID 24498346 DOI: 10.1371/Journal.Pone.0087646  0.536
2014 Ito K, Yanagida A, Okada K, Yamazaki Y, Nakauchi H, Kamiya A. Mesenchymal progenitor cells in mouse foetal liver regulate differentiation and proliferation of hepatoblasts. Liver International : Official Journal of the International Association For the Study of the Liver. 34: 1378-90. PMID 24238062 DOI: 10.1111/Liv.12387  0.524
2014 Mochizuki Y, Iida A, Lyons E, Kageyama R, Nakauchi H, Murakami A, Watanabe S. Use of cell type-specific transcriptome to identify genes specifically involved in Müller glia differentiation during retinal development. Developmental Neurobiology. 74: 426-437. PMID 24124169 DOI: 10.1002/Dneu.22131  0.401
2014 Hirabayashi M, Goto T, Tamura C, Sanbo M, Hara H, Kato-Itoh M, Sato H, Kobayashi T, Nakauchi H, Hochi S. Derivation of embryonic stem cell lines from parthenogenetically developing rat blastocysts. Stem Cells and Development. 23: 107-14. PMID 24010570 DOI: 10.1089/Scd.2013.0200  0.46
2014 Tsukiyama T, Kato-Itoh M, Nakauchi H, Ohinata Y. Correction: A Comprehensive system for generation and evaluation of induced pluripotent stem cells using piggyBac transposition (PLoS ONE (2014) 9, 3 (e92973) DOI: 10.1371/journal.pone.0092973) Plos One. 9. DOI: 10.1371/journal.pone.0101922  0.316
2014 Otani A, Koike T, Abe N, Nakamura T, Nishino T, Nakauchi H, Eto K. A Novel Chemical Approach to Expand Platelets Using Immortalized Megakaryocyte Progenitor Cells Derived from Human Induced Pluripotent Stem Cells Blood. 124: 3845-3845. DOI: 10.1182/Blood.V124.21.3845.3845  0.448
2014 Ishida T, Otsu M, Takahashi S, Higashihara M, Nakauchi H. A New Strategy to Overcome the Cell Dose Barrier to Umbilical Cord Blood Transplants: A Proof of Early Hematopoietic Reconstitution By Combined Multiple Units of Allogeneic Stem/Progenitor Cells Blood. 124: 3810-3810. DOI: 10.1182/Blood.V124.21.3810.3810  0.46
2014 Nishida C, Salama Y, Gritli I, Umemoto T, Nakauchi H, Hattori K, Beate H. Epidermal Growth Factor-like Domain 7 Promotes Hematopoietic Stem Cell Expansion and Increases Myeloid-Megakaryocytic Lineage Priming through beta3 Integrin Blood. 124: 2919-2919. DOI: 10.1182/Blood.V124.21.2919.2919  0.514
2014 Ishigaki T, Kobayashi S, Ohno N, Nakano N, Utsunomiya A, Yamazaki S, Watanabe N, Uchimaru K, Tojo A, Nakauchi H. Comprehensive Analysis of Surface Antigens on Adult T-Cell Leukemia/Lymphoma (ATL) Cells and Search for ATL-Initiating Cell Markers Blood. 124: 1674-1674. DOI: 10.1182/Blood.V124.21.1674.1674  0.396
2014 Matsunari H, Nakano K, Kanai T, Matsuda T, Maehara M, Watanabe M, Umeyama K, Nagaya M, Nakauchi H, Nagashima H. 26 In Vivo Exogenic Organ Generation With Organogenesis-Disabled Cloned Pigs As A Platform Reproduction, Fertility and Development. 26: 127-128. DOI: 10.1071/Rdv26N1Ab26  0.407
2014 Tadokoro Y, Eto K, Ema H, Yamazaki S, Yoshimura A, Nakauchi H, Hirao A. Control of self-renewal activity of hematopoietic stem cells by spred1 Experimental Hematology. 42. DOI: 10.1016/J.Exphem.2014.07.233  0.435
2013 Hirose S, Takayama N, Nakamura S, Nagasawa K, Ochi K, Hirata S, Yamazaki S, Yamaguchi T, Otsu M, Sano S, Takahashi N, Sawaguchi A, Ito M, Kato T, Nakauchi H, et al. Immortalization of erythroblasts by c-MYC and BCL-XL enables large-scale erythrocyte production from human pluripotent stem cells. Stem Cell Reports. 1: 499-508. PMID 24371805 DOI: 10.1016/J.Stemcr.2013.10.010  0.512
2013 Razak SR, Ueno K, Takayama N, Nariai N, Nagasaki M, Saito R, Koso H, Lai CY, Murakami M, Tsuji K, Michiue T, Nakauchi H, Otsu M, Watanabe S. Profiling of microRNA in human and mouse ES and iPS cells reveals overlapping but distinct microRNA expression patterns. Plos One. 8: e73532. PMID 24086284 DOI: 10.1371/Journal.Pone.0073532  0.319
2013 Saka K, Kawahara M, Teng J, Otsu M, Nakauchi H, Nagamune T. Top-down motif engineering of a cytokine receptor for directing ex vivo expansion of hematopoietic stem cells. Journal of Biotechnology. 168: 659-665. PMID 24070902 DOI: 10.1016/J.Jbiotec.2013.09.012  0.393
2013 Saito T, Yano F, Mori D, Ohba S, Hojo H, Otsu M, Eto K, Nakauchi H, Tanaka S, Chung U, Kawaguchi H. Generation of Col2a1-EGFP iPS cells for monitoring chondrogenic differentiation. Plos One. 8. PMID 24066106 DOI: 10.1371/Journal.Pone.0074137  0.51
2013 Miyanishi M, Mori Y, Seita J, Chen JY, Karten S, Chan CK, Nakauchi H, Weissman IL. Do pluripotent stem cells exist in adult mice as very small embryonic stem cells? Stem Cell Reports. 1: 198-208. PMID 24052953 DOI: 10.1016/J.Stemcr.2013.07.001  0.538
2013 Yamamoto R, Morita Y, Ooehara J, Hamanaka S, Onodera M, Rudolph KL, Ema H, Nakauchi H. Clonal analysis unveils self-renewing lineage-restricted progenitors generated directly from hematopoietic stem cells. Cell. 154: 1112-26. PMID 23993099 DOI: 10.1016/J.Cell.2013.08.007  0.533
2013 Kon A, Shih LY, Minamino M, Sanada M, Shiraishi Y, Nagata Y, Yoshida K, Okuno Y, Bando M, Nakato R, Ishikawa S, Sato-Otsubo A, Nagae G, Nishimoto A, Haferlach C, ... ... Nakauchi H, et al. Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms. Nature Genetics. 45: 1232-7. PMID 23955599 DOI: 10.1038/Ng.2731  0.324
2013 Yanagida A, Ito K, Chikada H, Nakauchi H, Kamiya A. An in vitro expansion system for generation of human iPS cell-derived hepatic progenitor-like cells exhibiting a bipotent differentiation potential. Plos One. 8: e67541. PMID 23935837 DOI: 10.1371/Journal.Pone.0067541  0.521
2013 Hirata S, Takayama N, Jono-Ohnishi R, Endo H, Nakamura S, Dohda T, Nishi M, Hamazaki Y, Ishii E, Kaneko S, Otsu M, Nakauchi H, Kunishima S, Eto K. Congenital amegakaryocytic thrombocytopenia iPS cells exhibit defective MPL-mediated signaling. The Journal of Clinical Investigation. 123: 3802-14. PMID 23908116 DOI: 10.1172/Jci64721  0.456
2013 Hamanaka S, Ooehara J, Morita Y, Ema H, Takahashi S, Miyawaki A, Otsu M, Yamaguchi T, Onodera M, Nakauchi H. Generation of transgenic mouse line expressing Kusabira Orange throughout body, including erythrocytes, by random segregation of provirus method. Biochemical and Biophysical Research Communications. 435: 586-91. PMID 23685154 DOI: 10.1016/J.Bbrc.2013.05.017  0.431
2013 Suzuki N, Yamazaki S, Yamaguchi T, Okabe M, Masaki H, Takaki S, Otsu M, Nakauchi H. Generation of engraftable hematopoietic stem cells from induced pluripotent stem cells by way of teratoma formation. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1424-31. PMID 23670574 DOI: 10.1038/Mt.2013.71  0.501
2013 Nakagawa Y, Nakamura S, Nakajima M, Endo H, Dohda T, Takayama N, Nakauchi H, Arai F, Fukuda T, Eto K. Two differential flows in a bioreactor promoted platelet generation from human pluripotent stem cell-derived megakaryocytes. Experimental Hematology. 41: 742-8. PMID 23618622 DOI: 10.1016/J.Exphem.2013.04.007  0.462
2013 Matsunari H, Nagashima H, Watanabe M, Umeyama K, Nakano K, Nagaya M, Kobayashi T, Yamaguchi T, Sumazaki R, Herzenberg LA, Nakauchi H. Blastocyst complementation generates exogenic pancreas in vivo in apancreatic cloned pigs. Proceedings of the National Academy of Sciences of the United States of America. 110: 4557-62. PMID 23431169 DOI: 10.1073/Pnas.1222902110  0.463
2013 Kiyohashi K, Kakinuma S, Kamiya A, Sakamoto N, Nitta S, Yamanaka H, Yoshino K, Fujiki J, Murakawa M, Kusano-Kitazume A, Shimizu H, Okamoto R, Azuma S, Nakagawa M, Asahina Y, ... ... Nakauchi H, et al. Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice. Hepatology (Baltimore, Md.). 57: 2502-13. PMID 23386589 DOI: 10.1002/Hep.26293  0.446
2013 Hiramoto T, Ebihara Y, Mizoguchi Y, Nakamura K, Yamaguchi K, Ueno K, Nariai N, Mochizuki S, Yamamoto S, Nagasaki M, Furukawa Y, Tani K, Nakauchi H, Kobayashi M, Tsuji K. Wnt3a stimulates maturation of impaired neutrophils developed from severe congenital neutropenia patient-derived pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 3023-8. PMID 23382209 DOI: 10.1073/Pnas.1217039110  0.477
2013 Usui A, Mochizuki Y, Iida A, Miyauchi E, Satoh S, Sock E, Nakauchi H, Aburatani H, Murakami A, Wegner M, Watanabe S. The early retinal progenitor-expressed gene Sox11 regulates the timing of the differentiation of retinal cells Development. 140: 740-750. PMID 23318640 DOI: 10.1242/Dev.090274  0.377
2013 Nishimura T, Kaneko S, Kawana-Tachikawa A, Tajima Y, Goto H, Zhu D, Nakayama-Hosoya K, Iriguchi S, Uemura Y, Shimizu T, Takayama N, Yamada D, Nishimura K, Ohtaka M, Watanabe N, ... ... Nakauchi H, et al. Generation of rejuvenated antigen-specific T cells by reprogramming to pluripotency and redifferentiation. Cell Stem Cell. 12: 114-26. PMID 23290140 DOI: 10.1016/J.Stem.2012.11.002  0.768
2013 Oikawa T, Kamiya A, Zeniya M, Chikada H, Hyuck AD, Yamazaki Y, Wauthier E, Tajiri H, Miller LD, Wang XW, Reid LM, Nakauchi H. Sal-like protein 4 (SALL4), a stem cell biomarker in liver cancers. Hepatology (Baltimore, Md.). 57: 1469-83. PMID 23175232 DOI: 10.1002/Hep.26159  0.429
2013 Nakajima-Takagi Y, Osawa M, Oshima M, Takagi H, Miyagi S, Endoh M, Endo TA, Takayama N, Eto K, Toyoda T, Koseki H, Nakauchi H, Iwama A. Role of SOX17 in hematopoietic development from human embryonic stem cells Blood. 121: 447-458. PMID 23169777 DOI: 10.1182/Blood-2012-05-431403  0.412
2013 Lin HT, Otsu M, Nakauchi H. Stem cell therapy: an exercise in patience and prudence. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 368: 20110334. PMID 23166396 DOI: 10.1098/Rstb.2011.0334  0.46
2013 Otsu M, Nakauchi H. [Utilization of the ES/iPS cell technology for hematopoietic stem cell transplantation]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 146-50. PMID 23133943  0.378
2013 Matsuno N, Yamamoto H, Watanabe N, Uchida N, Ota H, Nishida A, Ikebe T, Ishiwata K, Nakano N, Tsuji M, Asano-Mori Y, Izutsu K, Masuoka K, Wake A, Yoneyama A, ... Nakauchi H, et al. Rapid T-cell chimerism switch and memory T-cell expansion are associated with pre-engraftment immune reaction early after cord blood transplantation. British Journal of Haematology. 160: 255-8. PMID 23116322 DOI: 10.1111/Bjh.12097  0.366
2013 Kamiya A, Nakauchi H. Enrichment and clonal culture of hepatic stem/progenitor cells during mouse liver development. Methods in Molecular Biology (Clifton, N.J.). 945: 273-86. PMID 23097112 DOI: 10.1007/978-1-62703-125-7_16  0.471
2013 Hirabayashi M, Tamura C, Sanbo M, Kato-Itoh M, Kobayashi T, Nakauchi H, Hochi S. A retrospective analysis of germline competence in rat embryonic stem cell lines Transgenic Research. 22: 411-416. PMID 22875289 DOI: 10.1007/S11248-012-9638-7  0.341
2013 Matsunawa M, Yamamoto R, Sanada M, Sato A, Shiozawa Y, Yoshida K, Nagata Y, Kon A, Yoshizato T, Otsu M, Isono K, Koseki H, Nakauchi H, Ogawa S. Role Of Sf3b1 On Hematopoiesis Blood. 122: 600-600. DOI: 10.1182/Blood.V122.21.600.600  0.462
2013 Yamazaki S, Napier SC, Usui J, Ota Y, Takahashi S, Watanabe N, Nakauchi H. Novel Therapeutic Approach To Graft-Versus-Host Disease With Allele-Specific Anti-HLA Monoclonal Antibody Blood. 122: 4462-4462. DOI: 10.1182/Blood.V122.21.4462.4462  0.389
2013 Matsunari H, Nakano K, Kanai T, Sakai R, Watanabe M, Umeyama K, Kobayashi T, Yamaguchi T, Shiota A, Nagaya M, Nakauchi H, Nagashima H. 326 Generation Of A Double-Transgenic Pig With Pancreas-Specific Green And Liver-Specific Red Fluorescence Reproduction, Fertility and Development. 25: 311-311. DOI: 10.1071/Rdv25N1Ab326  0.339
2013 Kimura T, Yamazaki S, Takaku T, Yamaguchi T, Komatsu N, Nakauchi H. Human hematopoietic stem/progenitor cells hibernate in vascular niche harboring GFAP-expressing cells Experimental Hematology. 41. DOI: 10.1016/J.Exphem.2013.05.040  0.52
2012 Yamaguchi T, Hamanaka S, Kamiya A, Okabe M, Kawarai M, Wakiyama Y, Umino A, Hayama T, Sato H, Lee YS, Kato-Itoh M, Masaki H, Kobayashi T, Yamazaki S, Nakauchi H. Development of an all-in-one inducible lentiviral vector for gene specific analysis of reprogramming. Plos One. 7: e41007. PMID 22815895 DOI: 10.1371/Journal.Pone.0041007  0.519
2012 Nakamura S, Oshima M, Yuan J, Saraya A, Miyagi S, Konuma T, Yamazaki S, Osawa M, Nakauchi H, Koseki H, Iwama A. Bmi1 confers resistance to oxidative stress on hematopoietic stem cells. Plos One. 7: e36209. PMID 22606246 DOI: 10.1371/Journal.Pone.0036209  0.404
2012 Sekine K, Takebe T, Suzuki Y, Kamiya A, Nakauchi H, Taniguchi H. Highly efficient generation of definitive endoderm lineage from human induced pluripotent stem cells. Transplantation Proceedings. 44: 1127-9. PMID 22564643 DOI: 10.1016/J.Transproceed.2012.03.001  0.513
2012 Kobayashi T, Kato-Itoh M, Yamaguchi T, Tamura C, Sanbo M, Hirabayashi M, Nakauchi H. Identification of Rat Rosa26 Locus Enables Generation of Knock-In Rat Lines Ubiquitously Expressing tdTomato Stem Cells and Development. 21: 2981-2986. PMID 22564063 DOI: 10.1089/Scd.2012.0065  0.345
2012 Nishida C, Kusubata K, Tashiro Y, Gritli I, Sato A, Ohki-Koizumi M, Morita Y, Nagano M, Sakamoto T, Koshikawa N, Kuchimaru T, Kizaka-Kondoh S, Seiki M, Nakauchi H, Heissig B, et al. MT1-MMP plays a critical role in hematopoiesis by regulating HIF-mediated chemokine/cytokine gene transcription within niche cells. Blood. 119: 5405-16. PMID 22544701 DOI: 10.1182/Blood-2011-11-390849  0.421
2012 Usui JI, Kobayashi T, Yamaguchi T, Knisely AS, Nishinakamura R, Nakauchi H. Generation of kidney from pluripotent stem cells via blastocyst complementation. American Journal of Pathology. 180: 2417-2426. PMID 22507837 DOI: 10.1016/J.Ajpath.2012.03.007  0.422
2012 Hirabayashi M, Tamura C, Sanbo M, Goto T, Kato-Itoh M, Kobayashi T, Nakauchi H, Hochi S. Ability of tetraploid rat blastocysts to support fetal development after complementation with embryonic stem cells. Molecular Reproduction and Development. 79: 402-412. PMID 22499253 DOI: 10.1002/Mrd.22043  0.401
2012 Ghosn EE, Yamamoto R, Hamanaka S, Yang Y, Herzenberg LA, Nakauchi H, Herzenberg LA. Distinct B-cell lineage commitment distinguishes adult bone marrow hematopoietic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 5394-8. PMID 22431624 DOI: 10.1073/Pnas.1121632109  0.36
2012 Wang J, Sun Q, Morita Y, Jiang H, Gross A, Lechel A, Hildner K, Guachalla LM, Gompf A, Hartmann D, Schambach A, Wuestefeld T, Dauch D, Schrezenmeier H, Hofmann WK, ... Nakauchi H, et al. A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage. Cell. 148: 1001-14. PMID 22385964 DOI: 10.1016/J.Cell.2012.01.040  0.386
2012 Oguro H, Yuan J, Tanaka S, Miyagi S, Mochizuki-Kashio M, Ichikawa H, Yamazaki S, Koseki H, Nakauchi H, Iwama A. Lethal myelofibrosis induced by Bmi1-deficient hematopoietic cells unveils a tumor suppressor function of the polycomb group genes. The Journal of Experimental Medicine. 209: 445-54. PMID 22351929 DOI: 10.1084/Jem.20111709  0.403
2012 Takayama N, Eto K, Nakauchi H. [Potential usefulness of human iPS cells on the generation of platelets]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 69: 2161-5. PMID 22242314  0.303
2012 Kobayashi T, Nakauchi H. [From cell therapy to organ regeneration therapy: generation of functional organs from pluripotent stem cells]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 69: 2148-55. PMID 22242312  0.388
2012 Ito H, Kamiya A, Ito K, Yanagida A, Okada K, Nakauchi H. In vitro expansion and functional recovery of mature hepatocytes from mouse adult liver. Liver International : Official Journal of the International Association For the Study of the Liver. 32: 592-601. PMID 22222094 DOI: 10.1111/J.1478-3231.2011.02741.X  0.317
2012 Suzuki N, Yamazaki S, Ema H, Yamaguchi T, Nakauchi H, Takaki S. Homeostasis of hematopoietic stem cells regulated by the myeloproliferative disease associated-gene product Lnk/Sh2b3 via Bcl-xL. Experimental Hematology. 40: 166-74.e3. PMID 22101255 DOI: 10.1016/J.Exphem.2011.11.003  0.433
2012 Umemoto T, Yamato M, Ishihara J, Shiratsuchi Y, Utsumi M, Morita Y, Tsukui H, Terasawa M, Shibata T, Nishida K, Kobayashi Y, Petrich BG, Nakauchi H, Eto K, Okano T. Integrin-αvβ3 regulates thrombopoietin-mediated maintenance of hematopoietic stem cells. Blood. 119: 83-94. PMID 22096247 DOI: 10.1182/Blood-2011-02-335430  0.465
2012 Watanabe M, Kurome M, Matsunari H, Nakano K, Umeyema K, Shiota A, Nakauchi H, Nagashima H. The creation of transgenic pigs expressing human proteins using BAC-derived, full-length genes and intracytoplasmic sperm injection-mediated gene transfer Transgenic Research. 21: 605-618. PMID 22038447 DOI: 10.1007/S11248-011-9561-3  0.31
2012 Ishihara M, Nishida C, Tashiro Y, Gritli I, Rosenkvist J, Koizumi M, Okaji Y, Yamamoto R, Yagita H, Okumura K, Nishikori M, Wanaka K, Tsuda Y, Okada Y, Nakauchi H, et al. Plasmin inhibitor reduces T-cell lymphoid tumor growth by suppressing matrix metalloproteinase-9-dependent CD11b /F4/80 myeloid cell recruitment Leukemia. 26: 332-339. PMID 21931322 DOI: 10.1038/Leu.2011.203  0.342
2012 Saito R, Nakauchi H, Watanabe S. Serine/threonine kinase, Melk, regulates proliferation and glial differentiation of retinal progenitor cells. Cancer Science. 103: 42-9. PMID 21923749 DOI: 10.1111/J.1349-7006.2011.02104.X  0.368
2012 Okada K, Kamiya A, Ito K, Yanagida A, Ito H, Kondou H, Nishina H, Nakauchi H. Prospective isolation and characterization of bipotent progenitor cells in early mouse liver development. Stem Cells and Development. 21: 1124-33. PMID 21861758 DOI: 10.1089/Scd.2011.0229  0.41
2012 Sakurai M, Kunimoto H, Watanabe N, Fukuchi Y, Sadahira K, Yuasa S, Fukuda K, Yamazaki S, Nakauchi H, Ebihara Y, Tsuji K, Ito E, Harada Y, Harada H, Okamoto S, et al. Impaired Hematopoietic Differentiation of iPSCs Derived From Patients with FPD/AML Blood. 120: 767-767. DOI: 10.1182/Blood.V120.21.767.767  0.538
2012 Matsunawa M, Sanada M, Yamamoto R, Yoshida K, Nagata Y, Kon A, Yoshizato T, Otsu M, Nakauchi H, Ogawa S. Biological Analysis of SRSF2 Mutations in Leukemogenesis Blood. 120: 1282-1282. DOI: 10.1182/Blood.V120.21.1282.1282  0.44
2011 Yamazaki S, Ema H, Karlsson G, Yamaguchi T, Miyoshi H, Shioda S, Taketo MM, Karlsson S, Iwama A, Nakauchi H. Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche Cell. 147: 1146-1158. PMID 22118468 DOI: 10.1016/J.Cell.2011.09.053  0.432
2011 Watabe Y, Baba Y, Nakauchi H, Mizota A, Watanabe S. The role of Zic family zinc finger transcription factors in the proliferation and differentiation of retinal progenitor cells Biochemical and Biophysical Research Communications. 415: 42-47. PMID 22024047 DOI: 10.1016/J.Bbrc.2011.10.007  0.359
2011 Nishino T, Wang C, Mochizuki-Kashio M, Osawa M, Nakauchi H, Iwama A. Ex vivo expansion of human hematopoietic stem cells by garcinol, a potent inhibitor of histone acetyltransferase. Plos One. 6. PMID 21931675 DOI: 10.1371/Journal.Pone.0024298  0.46
2011 Hamanaka S, Yamaguchi T, Kobayashi T, Kato-Itoh M, Yamazaki S, Sato H, Umino A, Wakiyama Y, Arai M, Sanbo M, Hirabayashi M, Nakauchi H. Generation of germline-competent rat induced pluripotent stem cells. Plos One. 6. PMID 21789202 DOI: 10.1371/Journal.Pone.0022008  0.406
2011 Kawahara M, Chen J, Sogo T, Teng J, Otsu M, Onodera M, Nakauchi H, Ueda H, Nagamune T. Growth promotion of genetically modified hematopoietic progenitors using an antibody/c-Mpl chimera. Cytokine. 55: 402-408. PMID 21700475 DOI: 10.1016/J.Cyto.2011.05.024  0.367
2011 Yokoi T, Kobayashi H, Shimada Y, Eto Y, Ishige N, Kitagawa T, Otsu M, Nakauchi H, Ida H, Ohashi T. Minimum requirement of donor cells to reduce the glycolipid storage following bone marrow transplantation in a murine model of Fabry disease. Journal of Gene Medicine. 13: 262-268. PMID 21520359 DOI: 10.1002/Jgm.1566  0.449
2011 Tanimura S, Tadokoro Y, Inomata K, Binh NT, Nishie W, Yamazaki S, Nakauchi H, Tanaka Y, McMillan JR, Sawamura D, Yancey K, Shimizu H, Nishimura EK. Hair follicle stem cells provide a functional niche for melanocyte stem cells. Cell Stem Cell. 8: 177-87. PMID 21295274 DOI: 10.1016/J.Stem.2010.11.029  0.419
2011 Morita Y, Iseki A, Okamura S, Suzuki S, Nakauchi H, Ema H. Functional characterization of hematopoietic stem cells in the spleen. Experimental Hematology. 39: 351-359. PMID 21185906 DOI: 10.1016/J.Exphem.2010.12.008  0.496
2011 Nishimura K, Sano M, Ohtaka M, Furuta B, Umemura Y, Nakajima Y, Ikehara Y, Kobayashi T, Segawa H, Takayasu S, Sato H, Motomura K, Uchida E, Kanayasu-Toyoda T, Asashima M, ... Nakauchi H, et al. Development of defective and persistent Sendai virus vector: a unique gene delivery/expression system ideal for cell reprogramming. The Journal of Biological Chemistry. 286: 4760-71. PMID 21138846 DOI: 10.1074/Jbc.M110.183780  0.513
2011 Nakamura S, Takayama N, Nakauchi H, Eto K. Platelet Production System Using An Immortalized Megakaryocyte Cell Line Derived From Human Pluripotent Stem Cells Blood. 118: 2-2. DOI: 10.1182/Blood.V118.21.Mrg-1.Mrg-1  0.384
2011 Yamamoto R, Morita Y, Ema H, Ooehara J, Hamanaka S, Onodera M, Nakauchi H. Megakaryocyte Lineage Commitment in Hematopoietic Stem Cells Blood. 118: 909-909. DOI: 10.1182/Blood.V118.21.909.909  0.432
2011 Ishihara J, Umemoto T, Yamato M, Shiratsuchi Y, Petrich BG, Nakauchi H, Eto K, Kitamura T, Okano T. Nov/CCN3 Enhances Long-Term Repopulating Activity of Mouse Hematopoietic Stem Cells Via Intergin β3 Signaling Collaborating with Thrombopoietin Blood. 118: 862-862. DOI: 10.1182/Blood.V118.21.862.862  0.381
2011 Hiramoto T, Ebihara Y, Mizoguchi Y, Nakamura K, Mochizuki S, Yamamoto S, Matsuzaka E, Hanada S, Ohnishi R, Tani K, Eto K, Nakauchi H, Kobayashi M, Tsuji K. Suppressed Neutrophil Development in Hematopoiesis of Induced Pluripotent Stem Cells Derived From a Severe Congenital Neutropenia Patient with ELA2 Mutation Blood. 118: 730-730. DOI: 10.1182/Blood.V118.21.730.730  0.486
2011 Takayama N, Hirata S, Jono-Ohnishi R, Nakamura S, Hirose S, Endo H, Nishi M, Hamazaki Y, Kaneko S, Ishii E, Nakauchi H, Kunishima S, Eto K. Modeling Congenital Amegakaryocytic Thrombocytopenia Using Patient-Specific Induced Pluripotent Stem Cells Blood. 118: 703-703. DOI: 10.1182/Blood.V118.21.703.703  0.461
2011 Nishino T, Mikashima T, Yui M, Asai Y, Nakauchi H, Iwama A. A Chemical Approach for Ex Vivo Expansion of Human Hematopoietic Stem Cells Blood. 118: 481-481. DOI: 10.1182/Blood.V118.21.481.481  0.489
2011 Nakauchi Y, Zhu D, Takahashi S, Iwamoto A, Nakauchi H, Watanabe N. Development of Antigen Specific T Cells After HLA-Mismatched Umbilical Cord Blood Transplantation Blood. 118: 4544-4544. DOI: 10.1182/Blood.V118.21.4544.4544  0.403
2011 Nishida C, Kusubata K, Tashiro Y, Gritli I, Sato A, Ohki-Koizumi M, Seiki M, Nakauchi H, Heissig B, Hattori K. MT1-MMP Regulates Hematopoiesis Through HIF-Mediated Chemo-/Cytokine Release From the Bone Marrow Niche, Blood. 118: 3409-3409. DOI: 10.1182/Blood.V118.21.3409.3409  0.467
2011 Nishimura T, Kaneko S, Tajima Y, Takayama N, Tachikawa-Kawana A, Eto K, Nakauchi H. In Vitro Generation of Mature T Lymphocytes From Human Ips Cells and Genetic Analysis of TCR Gene Rearrangements Blood. 118: 2984-2984. DOI: 10.1182/Blood.V118.21.2984.2984  0.772
2011 Hirata S, Jono-Ohnishi R, Nishimura S, Takayama N, Nakamura S, Nakauchi H, Murata T, Eto K. Direct and Continuous Inhibition of ADAM17 Using a Novel Selective Inhibitor Restores Functional Platelet Yield From Human Pluripotent Stem Cells Blood. 118: 2323-2323. DOI: 10.1182/Blood.V118.21.2323.2323  0.344
2011 Lai C, Otsu M, Okabe M, Suzuki S, Yamazaki S, Onodera M, Ema H, Kakuta S, Iwakura Y, Nakauchi H. Evidence for the Involvement of CXCR4 Signaling in In Vivo Self-Renewal of Transplanted Hematopoietic Stem Cells Blood. 118: 1888-1888. DOI: 10.1182/Blood.V118.21.1888.1888  0.442
2011 Kon A, Sanada M, Yoshida K, Nagata Y, Shiraishi Y, Sato Y, Sato-Otsubo A, Yamamoto R, Nagasaki M, Suzuki Y, Yamaguchi T, Otsu M, Sugano S, Chiba S, Koeffler HP, ... ... Nakauchi H, et al. Functional Analysis of SRSF2 Mutations in Myelodysplastic Syndromes and Related Disorders Blood. 118: 1706-1706. DOI: 10.1182/Blood.V118.21.1706.1706  0.392
2011 Endo H, Takayama N, Koike T, Nakauchi H, Eto K. Stepwise Signaling and Low Oxygen Promote Hematopoietic Progenitor Emergence From Human Pluripotent Stem Cells Blood. 118: 1317-1317. DOI: 10.1182/Blood.V118.21.1317.1317  0.468
2011 Yamamoto H, Matsuno N, Watanabe N, Narita M, Nishida A, Ishiwata K, Nakano N, Tsuji M, Tsuchihashi R, Asano-Mori Y, Uchida N, Izutsu K, Wake A, Nakauchi H, Taniguchi S. Rapid Chimerism – Switch of Lymphocytes and Phenotypic Conversion of Naïve T Cells Early After Cord Blood Transplantation Biology of Blood and Marrow Transplantation. 17. DOI: 10.1016/J.Bbmt.2010.12.234  0.371
2010 Kumano K, Arai S, Hosoi M, Taoka K, Takayama N, Otsu M, Nagae G, Ueda K, Nakazaki K, Kamikubo Y, Eto K, Aburatani H, Nakauchi H, Kurokawa M. Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples. Blood. 119: 6234-6242. PMID 22592606 DOI: 10.1182/Blood-2011-07-367441  0.47
2010 Hayashi Y, Chan T, Warashina M, Fukuda M, Ariizumi T, Okabayashi K, Takayama N, Otsu M, Eto K, Furue MK, Michiue T, Ohnuma K, Nakauchi H, Asashima M. Reduction of N-glycolylneuraminic acid in human induced pluripotent stem cells generated or cultured under feeder- and serum-free defined conditions. Plos One. 5: e14099. PMID 21124894 DOI: 10.1371/Journal.Pone.0014099  0.504
2010 Takayama N, Nishimura S, Nakamura S, Shimizu T, Ohnishi R, Endo H, Yamaguchi T, Otsu M, Nishimura K, Nakanishi M, Sawaguchi A, Nagai R, Takahashi K, Yamanaka S, Nakauchi H, et al. Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells. The Journal of Experimental Medicine. 207: 2817-30. PMID 21098095 DOI: 10.1084/Jem.20100844  0.402
2010 Watanabe M, Umeyama K, Matsunari H, Takayanagi S, Haruyama E, Nakano K, Fujiwara T, Ikezawa Y, Nakauchi H, Nagashima H. Knockout of exogenous EGFP gene in porcine somatic cells using zinc-finger nucleases. Biochemical and Biophysical Research Communications. 402: 14-18. PMID 20875794 DOI: 10.1016/J.Bbrc.2010.09.092  0.412
2010 Kobayashi T, Yamaguchi T, Hamanaka S, Kato-Itoh M, Yamazaki Y, Ibata M, Sato H, Lee Y, Usui J, Knisely AS, Hirabayashi M, Nakauchi H. Generation of rat pancreas in mouse by interspecific blastocyst injection of pluripotent stem cells. Cell. 142: 787-799. PMID 20813264 DOI: 10.1016/J.Cell.2010.07.039  0.382
2010 Chiba T, Seki A, Aoki R, Ichikawa H, Negishi M, Miyagi S, Oguro H, Saraya A, Kamiya A, Nakauchi H, Yokosuka O, Iwama A. Bmi1 promotes hepatic stem cell expansion and tumorigenicity in both Ink4a/Arf-dependent and -independent manners in mice. Hepatology (Baltimore, Md.). 52: 1111-23. PMID 20648475 DOI: 10.1002/Hep.23793  0.507
2010 Kaneko S, Otsu M, Nakauchi H. Reprogramming adult hematopoietic cells. Current Opinion in Hematology. 17: 271-275. PMID 20571391 DOI: 10.1097/Moh.0B013E32833A25Ee  0.528
2010 Hirabayashi M, Kato M, Sanbo M, Kobayashi T, Hochi S, Nakauchi H. Rat transgenesis via embryonic stem cells electroporated with the Kusabira-orange gene. Molecular Reproduction and Development. 77: 474-474. PMID 20422708 DOI: 10.1002/Mrd.21181  0.447
2010 Morita Y, Ema H, Nakauchi H. Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment Journal of Experimental Medicine. 207: 1173-1182. PMID 20421392 DOI: 10.1084/Jem.20091318  0.522
2010 Sugawara T, Oguro H, Negishi M, Morita Y, Ichikawa H, Iseki T, Yokosuka O, Nakauchi H, Iwama A. FET family proto-oncogene Fus contributes to self-renewal of hematopoietic stem cells. Experimental Hematology. 38: 696-706. PMID 20412831 DOI: 10.1016/J.Exphem.2010.04.006  0.399
2010 Oguro H, Yuan J, Ichikawa H, Ikawa T, Yamazaki S, Kawamoto H, Nakauchi H, Iwama A. Poised lineage specification in multipotential hematopoietic stem and progenitor cells by the polycomb protein Bmi1. Cell Stem Cell. 6: 279-86. PMID 20207230 DOI: 10.1016/J.Stem.2010.01.005  0.493
2010 Ohki M, Ohki Y, Ishihara M, Nishida C, Tashiro Y, Akiyama H, Komiyama H, Lund LR, Nitta A, Yamada K, Zhu Z, Ogawa H, Yagita H, Okumura K, Nakauchi H, et al. Tissue type plasminogen activator regulates myeloid-cell dependent neoangiogenesis during tissue regeneration. Blood. 115: 4302-12. PMID 20110420 DOI: 10.1182/Blood-2009-08-236851  0.399
2010 Liao CH, Akazawa H, Tamagawa M, Ito K, Yasuda N, Kudo Y, Yamamoto R, Ozasa Y, Fujimoto M, Wang P, Nakauchi H, Nakaya H, Komuro I. Cardiac mast cells cause atrial fibrillation through PDGF-A-mediated fibrosis in pressure-overloaded mouse hearts. The Journal of Clinical Investigation. 120: 242-53. PMID 20038802 DOI: 10.1172/Jci39942  0.321
2010 Hirabayashi M, Kato M, Kobayashi T, Sanbo M, Yagi T, Hochi S, Nakauchi H. Establishment of rat embryonic stem cell lines that can participate in germline chimerae at high efficiency. Molecular Reproduction and Development. 77: 94. PMID 19899136 DOI: 10.1002/Mrd.21123  0.421
2010 Nishihama N, Ebihara Y, Ma F, Yang W, Tomizawa D, Mochizuki S, Yamaguchi K, Hiratsuka M, Furukawa Y, Oshimura M, Nakauchi H, Tsuji K. Hematopoiesis of Human Induced Pluripotent Stem Cells Derived From Patients with Down Syndrome Blood. 116: 881-881. DOI: 10.1182/Blood.V116.21.881.881  0.463
2010 Takayama N, Sano S, Shimizu T, Kawahata R, Endo H, Nakamura S, Ogawa S, Nakauchi H, Eto K. Epigenetic Memory Enables the Dominant Generation of Adult-Type Erythrocytes From Human Induced Pluripotent Stem Cells Blood. 116: 648-648. DOI: 10.1182/Blood.V116.21.648.648  0.409
2010 Nishimura T, Kaneko S, Gotoh H, Takayama N, Shimizu T, Iriguchi S, Tajima Y, Yasui Y, Watanabe N, Takahashi S, Eto K, Nakauchi H. Generation of Monoclonal TCR-Expressing Human T-Lineage Lymphocytes From Induced Pluripotent Stem Cells of Single Peripheral T-Lymphocyte Origin Blood. 116: 490-490. DOI: 10.1182/Blood.V116.21.490.490  0.756
2010 Nishida C, Heissig B, Tashiro Y, Seiki M, Nakauchi H, Hattori K. MT1-MMP Plays a Critical Role In the Modulation of Hematopoiesis. Blood. 116: 3851-3851. DOI: 10.1182/Blood.V116.21.3851.3851  0.315
2010 Suzuki S, Okabe M, Otsu M, Ema H, Nakauchi H. Irradiated Bone Marrow Environment Impairs Hematopoietic Stem Cells by Exposure to Tumor Necrosis Factor a. Blood. 116: 3724-3724. DOI: 10.1182/Blood.V116.21.3724.3724  0.392
2010 Yang W, Ma F, Matsumoto K, Nishihama N, Sagara H, Ebihara Y, Gu Y, Saito H, Zhu X, Nakauchi H, Tsuji K. Differentiation of Mature Eosinophils From Human Embryonic and Induced Pluripotent Stem Cells. Blood. 116: 1594-1594. DOI: 10.1182/Blood.V116.21.1594.1594  0.475
2010 Gaudreau M, Sharif-Askari E, Heyd F, Möröy T, Shimazu T, Esplin BL, Welner RS, Garrett KP, Nie L, Humphrey MB, Yang Q, Borghesi LA, Kincade PW, Yamane T, Washino A, ... ... Nakauchi H, et al. Hematopoietic stem cells (+iPS) (WS-010) Chairpersons: Hiromitsu Nakauchi, Haruhiko Koseki International Immunology. 22. DOI: 10.1093/Intimm/Dxq165  0.791
2010 Nakauchi H. Cytometry technologies for analysis of very small numbers of cells (LL2-5) Chairperson: Shigeo Koyasu International Immunology. 22. DOI: 10.1093/Intimm/Dxq093  0.321
2009 Nishino T, Miyaji K, Ishiwata N, Arai K, Yui M, Asai Y, Nakauchi H, Iwama A. Ex vivo expansion of human hematopoietic stem cells by a small-molecule agonist of c-MPL. Experimental Hematology. 37: 1364-1377. PMID 19744539 DOI: 10.1016/J.Exphem.2009.09.001  0.477
2009 Ishige I, Nagamura-Inoue T, Honda MJ, Harnprasopwat R, Kido M, Sugimoto M, Nakauchi H, Tojo A. Comparison of mesenchymal stem cells derived from arterial, venous, and Wharton's jelly explants of human umbilical cord. International Journal of Hematology. 90: 261-269. PMID 19657615 DOI: 10.1007/S12185-009-0377-3  0.412
2009 Xiao W, Hong H, Kawakami Y, Kato Y, Wu D, Yasudo H, Kimura A, Kubagawa H, Bertoli LF, Davis RS, Chau LA, Madrenas J, Hsia CC, Xenocostas A, Kipps TJ, ... ... Nakauchi H, et al. Tumor suppression by phospholipase C-beta3 via SHP-1-mediated dephosphorylation of Stat5. Cancer Cell. 16: 161-71. PMID 19647226 DOI: 10.1016/J.Ccr.2009.05.018  0.35
2009 Sanada M, Suzuki T, Shih LY, Otsu M, Kato M, Yamazaki S, Tamura A, Honda H, Sakata-Yanagimoto M, Kumano K, Oda H, Yamagata T, Takita J, Gotoh N, Nakazaki K, ... ... Nakauchi H, et al. Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms. Nature. 460: 904-8. PMID 19620960 DOI: 10.1038/Nature08240  0.313
2009 Okabe M, Otsu M, Ahn DH, Kobayashi T, Morita Y, Wakiyama Y, Onodera M, Eto K, Ema H, Nakauchi H. Definitive proof for direct reprogramming of hematopoietic cells to pluripotency Blood. 114: 1764-1767. PMID 19564635 DOI: 10.1182/Blood-2009-02-203695  0.559
2009 Kamiya A, Kakinuma S, Yamazaki Y, Nakauchi H. Enrichment and clonal culture of progenitor cells during mouse postnatal liver development in mice. Gastroenterology. 137: 1114-26, 1126.e1-14. PMID 19524574 DOI: 10.1053/J.Gastro.2009.06.001  0.482
2009 Yamazaki S, Nakauchi H. Insights into signaling and function of hematopoietic stem cells at the single-cell level. Current Opinion in Hematology. 16: 255-258. PMID 19465850 DOI: 10.1097/Moh.0B013E32832C6705  0.513
2009 Kakinuma S, Ohta H, Kamiya A, Yamazaki Y, Oikawa T, Okada K, Nakauchi H. Analyses of cell surface molecules on hepatic stem/progenitor cells in mouse fetal liver. Journal of Hepatology. 51: 127-38. PMID 19439389 DOI: 10.1016/J.Jhep.2009.02.033  0.485
2009 Ogaeri T, Eto K, Otsu M, Ema H, Nakauchi H. The Actin Polymerization Regulator WAVE2 Is Required for Early Bone Marrow Repopulation by Hematopoietic Stem Cells Stem Cells. 27: 1120-1129. PMID 19415782 DOI: 10.1002/Stem.42  0.38
2009 Matsumoto K, Isagawa T, Nishimura T, Ogaeri T, Eto K, Miyazaki S, Miyazaki J, Aburatani H, Nakauchi H, Ema H. Stepwise development of hematopoietic stem cells from embryonic stem cells. Plos One. 4: e4820. PMID 19287487 DOI: 10.1371/Journal.Pone.0004820  0.799
2009 Sogo T, Kawahara M, Ueda H, Otsu M, Onodera M, Nakauchi H, Nagamune T. T cell growth control using hapten-specific antibody/interleukin-2 receptor chimera. Cytokine. 46: 127-136. PMID 19223197 DOI: 10.1016/J.Cyto.2008.12.020  0.31
2009 Kakinuma S, Nakauchi H, Watanabe M. Hepatic stem/progenitor cells and stem-cell transplantation for the treatment of liver disease. Journal of Gastroenterology. 44: 167-172. PMID 19214659 DOI: 10.1007/S00535-008-2297-Z  0.46
2009 Yamazaki S, Suzuki N, Saito T, Ishii Y, Takiguchi M, Nakauchi H, Watanabe N. A rapid and efficient strategy to generate allele-specific anti-HLA monoclonal antibodies. Journal of Immunological Methods. 343: 56-60. PMID 19187783 DOI: 10.1016/J.Jim.2009.01.007  0.303
2009 Oikawa T, Kamiya A, Kakinuma S, Zeniya M, Nishinakamura R, Tajiri H, Nakauchi H. Sall4 regulates cell fate decision in fetal hepatic stem/progenitor cells. Gastroenterology. 136: 1000-11. PMID 19185577 DOI: 10.1053/J.Gastro.2008.11.018  0.479
2009 Yashiro Y, Bannai H, Minowa T, Yabiku T, Miyano S, Osawa M, Iwama A, Nakauchi H. Transcriptional profiling of hematopoietic stem cells by high-throughput sequencing. International Journal of Hematology. 89: 24-33. PMID 19050837 DOI: 10.1007/S12185-008-0212-2  0.366
2009 Yamazaki S, Iwama A, Takayanagi S, Eto K, Ema H, Nakauchi H. TGF-beta as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation. Blood. 113: 1250-1256. PMID 18945958 DOI: 10.1182/Blood-2008-04-146480  0.396
2009 Kim DK, Kojima M, Fukushima T, Miyasaka M, Nakauchi H. Engraftment of human myelodysplastic syndrome derived cell line in transgenic severe combined immunodeficient (TG-SCID) mice expressing human GM-CSF and IL-3 European Journal of Haematology. 61: 93-99. PMID 9714520 DOI: 10.1111/J.1600-0609.1998.Tb01067.X  0.387
2009 Ema H, Nakauchi H. Hematopoietic Stem Cells for Regenerative Medicine Ieee Transactions On Intelligent Transportation Systems. 14: 16-23. DOI: 10.5363/Tits.14.8_16  0.504
2009 Nishino T, Miyaji K, Ishiwata N, Arai K, Yui M, Asai Y, Nakauchi H, Iwama A. Ex Vivo Expansion of Human Hematopoietic Stem Cells by a Small-Molecule Agonist of c-MPL. Blood. 114: 500-500. DOI: 10.1182/Blood.V114.22.500.500  0.514
2009 Shimizu T, Ito A, Nakagawa A, Nishimura T, Yamazaki S, Iriguchi S, Kaneko S, Nakauchi H. Establishment of Mouse PMF Model by the Introduction of Constitutive STAT5a Into Purified Hematopoietic Stem Cells. Blood. 114: 3900-3900. DOI: 10.1182/Blood.V114.22.3900.3900  0.766
2009 Umemoto T, Yamato M, Shiratsuchi Y, Tsukada K, Utsumi M, Morita Y, Terasawa M, Shibata T, Nishida K, Kobayashi Y, Petrich BG, Ginsberg MH, Nakauchi H, Eto K, Okano T. CD61/ Integrin β3 Ligation Contributes to the Thrombopoietin-Mediated Niche Function of Mouse Hematopoietic Stem Cells. Blood. 114: 383-383. DOI: 10.1182/Blood.V114.22.383.383  0.362
2009 Nishida C, Beate H, Seiki M, Nakauchi H, Hattori K. MT1-MMP Is Required for Hematopoietic Maturation in the BM Niche. Blood. 114: 3634-3634. DOI: 10.1182/Blood.V114.22.3634.3634  0.397
2009 Sanada M, Suzuki T, Shih L, Otsu M, Kato M, Yamazaki S, Honda H, Sakata MY, Kumano K, Oda H, Takita J, Kawamata N, Onodera M, Hayashi Y, Kurokawa M, ... ... Nakauchi H, et al. Unique Gain-of-Function of Mutated c-CBL Tumor Suppresor in Myeloid Neoplasms. Blood. 114: 2970-2970. DOI: 10.1182/Blood.V114.22.2970.2970  0.309
2009 Takayama N, Nakamura S, Nishimura S, Ohnishi R, Takahashi K, Yamanaka S, Eto K, Nakauchi H. Cancellation of c-MYC Silencing in Human Induced Pluripotent Stem Cells Contributes to the Efficient in Vitro Production of Platelets with the Ability of Hemostasis In Vivo. Blood. 114: 1488-1488. DOI: 10.1182/Blood.V114.22.1488.1488  0.487
2008 Hyun I, Lindvall O, Ahrlund-Richter L, Cattaneo E, Cavazzana-Calvo M, Cossu G, De Luca M, Fox IJ, Gerstle C, Goldstein RA, Hermerén G, High KA, Kim HO, Lee HP, Levy-Lahad E, ... ... Nakauchi H, et al. New ISSCR guidelines underscore major principles for responsible translational stem cell research. Cell Stem Cell. 3: 607-9. PMID 19041777 DOI: 10.1016/J.Stem.2008.11.009  0.451
2008 Suzuki A, Sekiya S, Onishi M, Oshima N, Kiyonari H, Nakauchi H, Taniguchi H. Flow cytometric isolation and clonal identification of self‐renewing bipotent hepatic progenitor cells in adult mouse liver Hepatology. 48: 1964-1978. PMID 18837044 DOI: 10.1002/Hep.22558  0.475
2008 Nakauchi H. [Recent progress in stem cell biology and its implications for future medicine]. [Rinsho Ketsueki] the Japanese Journal of Clinical Hematology. 49: 1515-21. PMID 18833936  0.384
2008 Chiba T, Miyagi S, Saraya A, Aoki R, Seki A, Morita Y, Yonemitsu Y, Yokosuka O, Taniguchi H, Nakauchi H, Iwama A. The polycomb gene product BMI1 contributes to the maintenance of tumor-initiating side population cells in hepatocellular carcinoma. Cancer Research. 68: 7742-9. PMID 18829528 DOI: 10.1158/0008-5472.Can-07-5882  0.432
2008 Ma F, Ebihara Y, Umeda K, Sakai H, Hanada S, Zhang H, Zaike Y, Tsuchida E, Nakahata T, Nakauchi H, Tsuji K. Generation of functional erythrocytes from human embryonic stem cell-derived definitive hematopoiesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 13087-92. PMID 18755895 DOI: 10.1073/Pnas.0802220105  0.529
2008 Nishikii H, Eto K, Tamura N, Hattori K, Heissig B, Kanaji T, Sawaguchi A, Goto S, Ware J, Nakauchi H. Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells. The Journal of Experimental Medicine. 205: 1917-27. PMID 18663123 DOI: 10.1084/Jem.20071482  0.447
2008 Sanuki S, Hamanaka S, Kaneko S, Otsu M, Karasawa S, Miyawaki A, Nakauchi H, Nagasawa T, Onodera M. A new red fluorescent protein that allows efficient marking of murine hematopoietic stem cells. The Journal of Gene Medicine. 10: 965-71. PMID 18613301 DOI: 10.1002/Jgm.1232  0.455
2008 Krishnamurthy P, Schwab M, Takenaka K, Nachagari D, Morgan J, Leslie M, Du W, Boyd K, Cheok M, Nakauchi H, Marzolini C, Kim RB, Poonkuzhali B, Schuetz E, Evans W, et al. Transporter-mediated protection against thiopurine-induced hematopoietic toxicity. Cancer Research. 68: 4983-9. PMID 18593894 DOI: 10.1158/0008-5472.Can-07-6790  0.303
2008 Kamiya A, Kakinuma S, Onodera M, Miyajima A, Nakauchi H. Prospero-related homeobox 1 and liver receptor homolog 1 coordinated regulate long-term proliferation of murine fetal hepatoblasts Hepatology. 48: 252-264. PMID 18571787 DOI: 10.1002/Hep.22303  0.454
2008 Watanabe N, Takahashi S, Ishige M, Ishii Y, Ooi J, Tomonari A, Tsukada N, Konuma T, Kato S, Sato A, Tojo A, Nakauchi H. Recipient-derived cells after cord blood transplantation: dynamics elucidated by multicolor FACS, reflecting graft failure and relapse. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 14: 693-701. PMID 18489995 DOI: 10.1016/J.Bbmt.2008.04.001  0.428
2008 Takizawa H, Eto K, Yoshikawa A, Nakauchi H, Takatsu K, Takaki S. Growth and maturation of megakaryocytes is regulated by Lnk/Sh2b3 adaptor protein through crosstalk between cytokine- and integrin-mediated signals. Experimental Hematology. 36: 897-906. PMID 18456388 DOI: 10.1016/J.Exphem.2008.02.004  0.324
2008 Takayama N, Nishikii H, Usui J, Tsukui H, Sawaguchi A, Hiroyama T, Eto K, Nakauchi H. Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors. Blood. 111: 5298-306. PMID 18388179 DOI: 10.1182/Blood-2007-10-117622  0.503
2008 Ema H, Nakauchi H. Bloodlines of haematopoietic stem cell research in Japan Philosophical Transactions of the Royal Society B. 363: 2089-2097. PMID 18375375 DOI: 10.1098/Rstb.2008.2263  0.514
2008 Seita J, Asakawa M, Ooehara J, Takayanagi S, Morita Y, Watanabe N, Fujita K, Kudo M, Mizuguchi J, Ema H, Nakauchi H, Yoshimoto T. Interleukin-27 directly induces differentiation in hematopoietic stem cells. Blood. 111: 1903-12. PMID 18042804 DOI: 10.1182/Blood-2007-06-093328  0.401
2008 Nabekura T, Nagasawa T, Nakauchi H, Onodera M. An immunotherapy approach with dendritic cells genetically modified to express the tumor-associated antigen, HER2. Cancer Immunology, Immunotherapy. 57: 611-622. PMID 17786440 DOI: 10.1007/S00262-007-0399-8  0.316
2008 Eto K, Nakauchi H. Transfusion therapy by blood platelets derived from embryonic stem cells or induced pluripotent stem cells Drug Delivery System. 23: 553-559. DOI: 10.2745/Dds.23.553  0.485
2008 Ooehara J, Takano H, Takayanagi S, Nakauchi H, Ema H. In Vitro Myelo-Lymphoid Colony Formation by Mouse Hematopoietic Stem Cells Blood. 112: 3861-3861. DOI: 10.1182/Blood.V112.11.3861.3861  0.502
2008 Iseki A, Morita Y, Nakauchi H, Ema H. Hematopoietic Stem Cells in the Mouse Spleen Blood. 112: 2421-2421. DOI: 10.1182/Blood.V112.11.2421.2421  0.544
2008 Takayama N, Eto K, Nakauchi H, Yamanaka S. Generation of Blood Cells from Human Ips Cells in Vitro through the Hematopoietic Progenitors Concentrated within the Unique Structures, Ips-Sac. Blood. 112: 1992-1992. DOI: 10.1182/Blood.V112.11.1992.1992  0.49
2008 Nakauchi H. Stem Cells : 幹細胞研究の新しい展開と新しい医療への期待 The Japanese Journal of Clinical Hematology. 49: 1515-1521. DOI: 10.11406/Rinketsu.49.1515  0.51
2008 Tsukada N, Ishige M, Konuma T, Kato S, Kasahara S, Tomonari A, Ooi J, Tojo A, Watanabe N, Nakauchi H, Masuko M, Furukawa T, Aizawa Y, Takahashi S. 361: The Pharmacodynamic Analysis between Cyclosporine a (CsA) and Cytokine Profiles of CD4+ T Lymphocytes for the Development of Optimized Immunosuppressive Therapy with CsA after Unrelated Cord Blood Transplantation (CBT) Biology of Blood and Marrow Transplantation. 14: 132. DOI: 10.1016/J.Bbmt.2007.12.371  0.314
2007 Heissig B, Lund LR, Akiyama H, Ohki M, Morita Y, Rømer J, Nakauchi H, Okumura K, Ogawa H, Werb Z, Danø K, Hattori K. The plasminogen fibrinolytic pathway is required for hematopoietic regeneration. Cell Stem Cell. 1: 658-70. PMID 18371407 DOI: 10.1016/J.Stem.2007.10.012  0.469
2007 Miyamoto K, Araki KY, Naka K, Arai F, Takubo K, Yamazaki S, Matsuoka S, Miyamoto T, Ito K, Ohmura M, Chen C, Hosokawa K, Nakauchi H, Nakayama K, Nakayama KI, et al. Foxo3a is essential for maintenance of the hematopoietic stem cell pool. Cell Stem Cell. 1: 101-112. PMID 18371339 DOI: 10.1016/J.Stem.2007.02.001  0.511
2007 Chiba T, Zheng Y, Kita K, Yokosuka O, Saisho H, Onodera M, Miyoshi H, Nakano M, Zen Y, Nakanuma Y, Nakauchi H, Iwama A, Taniguchi H. Enhanced self-renewal capability in hepatic stem/progenitor cells drives cancer initiation. Gastroenterology. 133: 937-950. PMID 17673212 DOI: 10.1053/J.Gastro.2007.06.016  0.505
2007 Yamazaki S, Iwama A, Morita Y, Eto K, Ema H, Nakauchi H. Cytokine signaling, lipid raft clustering, and HSC hibernation. Annals of the New York Academy of Sciences. 1106: 54-63. PMID 17442772 DOI: 10.1196/Annals.1392.017  0.365
2007 Tadokoro Y, Ema H, Okano M, Li E, Nakauchi H. De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells Journal of Experimental Medicine. 204: 715-722. PMID 17420264 DOI: 10.1084/Jem.20060750  0.485
2007 Kato Y, Koseki H, Vidal M, Nakauchi H, Iwama A. Unique composition of polycomb repressive complex 1 in hematopoietic stem cells International Journal of Hematology. 85: 179-181. PMID 17322001 DOI: 10.1532/Ijh97.06235  0.449
2007 Seita J, Ema H, Ooehara J, Yamazaki S, Tadokoro Y, Yamasaki A, Eto K, Takaki S, Takatsu K, Nakauchi H. Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction. Proceedings of the National Academy of Sciences of the United States of America. 104: 2349-54. PMID 17284614 DOI: 10.1073/Pnas.0606238104  0.489
2007 Hasegawa Y, Ogihara T, Yamada T, Ishigaki Y, Imai J, Uno K, Gao J, Kaneko K, Ishihara H, Sasano H, Nakauchi H, Oka Y, Katagiri H. Bone marrow (BM) transplantation promotes β-cell regeneration after acute injury through BM cell mobilization Endocrinology. 148: 2006-2015. PMID 17255204 DOI: 10.1210/En.2006-1351  0.448
2007 Hamanaka S, Nabekura T, Otsu M, Yoshida H, Nagata M, Usui J, Takahashi S, Nagasawa T, Nakauchi H, Onodera M. Stable transgene expression in mice generated from retrovirally transduced embryonic stem cells. Molecular Therapy. 15: 560-565. PMID 17180117 DOI: 10.1038/Sj.Mt.6300063  0.452
2007 Choudhury AR, Ju Z, Djojosubroto MW, Schienke A, Lechel A, Schaetzlein S, Jiang H, Stepczynska A, Wang C, Buer J, Lee HW, von Zglinicki T, Ganser A, Schirmacher P, Nakauchi H, et al. Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation. Nature Genetics. 39: 99-105. PMID 17143283 DOI: 10.1038/Ng1937  0.397
2007 Ma F, Ebihara Y, Umeda K, Sakai H, Hanada S, Zhang H, Tsuchida E, Nakahata T, Nakauchi H, Tsuji K. Clonal Analysis of Progressive Maturation of Erythroid Cells from Human Embryonic Stem Cell-Derived Definitive Hematopoiesis. Blood. 110: 2236-2236. DOI: 10.1182/Blood.V110.11.2236.2236  0.48
2007 Takahashi S, Watanabe N, Iezaki M, Shibata T, Ooi J, Tomonari A, Tsukada N, Konuma T, Kobayashi T, Sato A, Kato S, Nakauchi H. Flow Cytometric Analysis of Donor-Recipient Chimerism Using Anti-HLA Antibody after HLA-Mismatched Cord Blood Transplantation. Blood. 110: 2008-2008. DOI: 10.1182/Blood.V110.11.2008.2008  0.406
2006 Ema H, Morita Y, Yamazaki S, Matsubara A, Seita J, Tadokoro Y, Kondo H, Takano H, Nakauchi H. Adult mouse hematopoietic stem cells: purification and single-cell assays. Nature Protocols. 1: 2979-87. PMID 17406558 DOI: 10.1038/Nprot.2006.447  0.531
2006 Oguro H, Iwama A, Morita Y, Kamijo T, van Lohuizen M, Nakauchi H. Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice. The Journal of Experimental Medicine. 203: 2247-53. PMID 16954369 DOI: 10.1084/Jem.20052477  0.42
2006 Sakaguchi T, Nishimoto M, Miyagi S, Iwama A, Morita Y, Iwamori N, Nakauchi H, Kiyonari H, Muramatsu M, Okuda A. Putative "stemness" gene jam-B is not required for maintenance of stem cell state in embryonic, neural, or hematopoietic stem cells. Molecular and Cellular Biology. 26: 6557-6570. PMID 16914739 DOI: 10.1128/Mcb.00729-06  0.53
2006 Yamazaki S, Iwama A, Takayanagi S, Morita Y, Eto K, Ema H, Nakauchi H. Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells The Embo Journal. 25: 3515-3523. PMID 16858398 DOI: 10.1038/Sj.Emboj.7601236  0.403
2006 Morita Y, Ema H, Yamazaki S, Nakauchi H. Non-side-population hematopoietic stem cells in mouse bone marrow. Blood. 108: 2850-2856. PMID 16804114 DOI: 10.1182/Blood-2006-03-010207  0.462
2006 Chiba T, Kita K, Zheng Y, Yokosuka O, Saisho H, Iwama A, Nakauchi H, Taniguchi H. Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties. Hepatology. 44: 240-251. PMID 16799977 DOI: 10.1002/Hep.21227  0.457
2006 Furuta C, Ema H, Takayanagi S, Ogaeri T, Okamura D, Matsui Y, Nakauchi H. Discordant developmental waves of angioblasts and hemangioblasts in the early gastrulating mouse embryo Development. 133: 2771-2779. PMID 16794034 DOI: 10.1242/Dev.02440  0.42
2006 Sakaguchi M, Shingo T, Shimazaki T, Okano HJ, Shiwa M, Ishibashi S, Oguro H, Ninomiya M, Kadoya T, Horie H, Shibuya A, Mizusawa H, Poirier F, Nakauchi H, Sawamoto K, et al. A carbohydrate-binding protein, Galectin-1, promotes proliferation of adult neural stem cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 7112-7. PMID 16636291 DOI: 10.1073/Pnas.0508793103  0.4
2006 Takayanagi S, Hiroyama T, Yamazaki S, Nakajima T, Morita Y, Usui J, Eto K, Motohashi T, Shiomi K, Keino-Masu K, Masu M, Oike Y, Mori S, Yoshida N, Iwama A, ... Nakauchi H, et al. Genetic marking of hematopoietic stem and endothelial cells: identification of the Tmtsp gene encoding a novel cell surface protein with the thrombospondin-1 domain. Blood. 107: 4317-25. PMID 16455951 DOI: 10.1182/Blood-2005-09-3747  0.504
2006 Ema H, Kinda M, Takano Y, Oehara A, Maeda A, Nakauchi H. [Diversity of hematopoietic stem cells]. [Rinsho Ketsueki] the Japanese Journal of Clinical Hematology. 46: 170-8. PMID 16447711  0.414
2006 Kamiya A, Gonzalez FJ, Nakauchi H. Identification and differentiation of hepatic stem cells during liver development. Frontiers in Bioscience. 11: 1302-1310. PMID 16368517 DOI: 10.2741/1884  0.472
2006 Nabekura T, Otsu M, Nagasawa T, Nakauchi H, Onodera M. Potent Vaccine Therapy with Dendritic Cells Genetically Modified by the Gene-Silencing-Resistant Retroviral Vector GCDNsap Molecular Therapy. 13: 301-309. PMID 16311073 DOI: 10.1016/J.Ymthe.2005.09.021  0.383
2006 Nakauchi H, Sudo K, Ema H. Quantitative assessment of the stem cell self-renewal capacity. Annals of the New York Academy of Sciences. 938: 18-25. PMID 11458506 DOI: 10.1111/J.1749-6632.2001.Tb03570.X  0.51
2006 Matsubara A, Ooehara J, Yamazaki Y, Takano H, Nakauchi H, Ema H. Myeloid Lineage Restriction Is Prior to and Independent of Lymphoid Lineage Restriction. Blood. 108: 4174-4174. DOI: 10.1182/Blood.V108.11.4174.4174  0.432
2006 Furuta C, Ema H, Taya K, Nakauchi H. Hematopoiesis Arises Independent of Vasculogenesis in the Early Mouse Embryos. Blood. 108: 4167-4167. DOI: 10.1182/Blood.V108.11.4167.4167  0.451
2006 Takahashi S, Ooi J, Tomonari A, Tsukada N, Konuma T, Kobayashi T, Sato A, Tojo A, Watanabe N, Nakauchi H, Asano S. Low Incidence of Cytomegalovirus Infection Associated with Rapid Cell-Mediated Immune Reconstitution after Cord Blood Transplantation Using Full Conditioning Regimen Containing 12Gy Total Body Irradiation. Blood. 108: 2926-2926. DOI: 10.1182/Blood.V108.11.2926.2926  0.388
2006 Takayama N, Nishikii H, Hiroyama T, Nakamura Y, Tsukui H, Eto K, Nakauchi H. Human Embryonic Stem Cell-Derived “NET-Like” Structure Serves as a Hematopoietic Progenitor Niche and Favors Generation of Mature Megakaryocytes and Functional Platelets. Blood. 108: 1665-1665. DOI: 10.1182/Blood.V108.11.1665.1665  0.5
2006 Nishikii H, Eto K, Kanaji T, Ware J, Nakauchi H. Metalloproteinase Regulation Determines Integrin αIIbβ3 Function and Enhances the Capacity of ES Cell-Derived Platelets. Blood. 108: 140-140. DOI: 10.1182/Blood.V108.11.140.140  0.394
2006 Akiyama H, Lund LR, Morita Y, Nakauchi H, Ogawa H, Okumura K, Dano K, Werb Z, Heissig B, Hattori K. Novel Functions for a Fibrinolytic Pathway in Controlling the Stem Cell Niche. Blood. 108: 1394-1394. DOI: 10.1182/Blood.V108.11.1394.1394  0.524
2006 Ema H, Seita J, Ooehara J, Iseki A, Takano H, Nakauchi H. Adaptor Protein Lnk Negatively Controls the Likelihood of Self-Renewal in Hematopoietic Stem Cells. Blood. 108: 1316-1316. DOI: 10.1182/Blood.V108.11.1316.1316  0.49
2006 Onodera M, Kaneko S, Otsu M, Kojima H, Sumazaki R, Toma S, Bonini C, Bordignon C, Nakauchi H, Nagasawa T. 1107. Gene Therapy Clinical Trials for Relapsed Leukemia with Infusions of the Suicide-Gene Transduced Donor Lymphocytes in Japan Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.1212  0.377
2005 Ema H, Morita Y, Nakauchi H, Matsuzaki Y. Isolation of murine hematopoietic stem cells and progenitor cells. Current Protocols in Immunology. 67. PMID 18432947 DOI: 10.1002/0471142735.Im22B01S67  0.505
2005 Usui J, Osawa M, Yamazaki S, Morita Y, Koyama A, Nakauchi H. Identification of immature podocyte specific antigen using retrovirus-mediated gene transfer and cell sorting. Clinical and Experimental Nephrology. 9: 292-296. PMID 16362155 DOI: 10.1007/S10157-005-0389-0  0.356
2005 Matsubara A, Iwama A, Yamazaki S, Furuta C, Hirasawa R, Morita Y, Osawa M, Motohashi T, Eto K, Ema H, Kitamura T, Vestweber D, Nakauchi H. Endomucin, a CD34-like sialomucin, marks hematopoietic stem cells throughout development Journal of Experimental Medicine. 202: 1483-1492. PMID 16314436 DOI: 10.1084/Jem.20051325  0.491
2005 Nakauchi H, Oguro H, Negishi M, Iwama A. Polycomb gene product Bmi-1 regulates stem cell self-renewal. Ernst Schering Research Foundation Workshop. 85-100. PMID 16080288 DOI: 10.1007/3-540-37644-5_6  0.304
2005 Almeida-Porada G, Crappnell K, Porada C, Benoit B, Nakauchi H, Quesenberry P, Zanjani ED. In vivo haematopoietic potential of human neural stem cells British Journal of Haematology. 130: 276-283. PMID 16029457 DOI: 10.1111/J.1365-2141.2005.05588.X  0.438
2005 Kato Y, Iwama A, Tadokoro Y, Shimoda K, Minoguchi M, Akira S, Tanaka M, Miyajima A, Kitamura T, Nakauchi H. Selective activation of STAT5 unveils its role in stem cell self-renewal in normal and leukemic hematopoiesis Journal of Experimental Medicine. 202: 169-179. PMID 15998795 DOI: 10.1084/Jem.20042541  0.488
2005 Iseki H, Shimizukawa R, Sugiyama F, Kunita S, Iwama A, Onodera M, Nakauchi H, Yagami K. Parvovirus Nonstructural Proteins Induce an Epigenetic Modification through Histone Acetylation in Host Genes and Revert Tumor Malignancy to Benignancy Journal of Virology. 79: 8886-8893. PMID 15994782 DOI: 10.1128/Jvi.79.14.8886-8893.2005  0.366
2005 Hishikawa K, Marumo T, Miura S, Nakanishi A, Matsuzaki Y, Shibata K, Ichiyanagi T, Kohike H, Komori T, Takahashi I, Takase O, Imai N, Yoshikawa M, Inowa T, Hayashi M, ... ... Nakauchi H, et al. Musculin/MyoR is expressed in kidney side population cells and can regulate their function. The Journal of Cell Biology. 169: 921-8. PMID 15967813 DOI: 10.1083/Jcb.200412167  0.366
2005 Ema H, Sudo K, Seita J, Matsubara A, Morita Y, Osawa M, Takatsu K, Takaki S, Nakauchi H. Quantification of self-renewal capacity in single hematopoietic stem cells from normal and Lnk-deficient mice. Developmental Cell. 8: 907-14. PMID 15935779 DOI: 10.1016/J.Devcel.2005.03.019  0.409
2005 Hishikawa K, Marumo T, Miura S, Nakanishi A, Matsuzaki Y, Shibata K, Kohike H, Komori T, Hayashi M, Nakaki T, Nakauchi H, Okano H, Fujita T. Leukemia inhibitory factor induces multi-lineage differentiation of adult stem-like cells in kidney via kidney-specific cadherin 16. Biochemical and Biophysical Research Communications. 328: 288-91. PMID 15670782 DOI: 10.1016/J.Bbrc.2004.12.167  0.458
2005 Kaneko S, Nagasawa T, Nakauchi H, Onodera M. An in vivo assay for retrovirally transduced human peripheral T lymphocytes using nonobese diabetic/severe combined immunodeficiency mice Experimental Hematology. 33: 35-41. PMID 15661396 DOI: 10.1016/J.Exphem.2004.10.006  0.451
2004 Yasuda T, Shirakata M, Iwama A, Ishii A, Ebihara Y, Osawa M, Honda K, Shinohara H, Sudo K, Tsuji K, Nakauchi H, Iwakura Y, Hirai H, Oda H, Yamamoto T, et al. Role of Dok-1 and Dok-2 in Myeloid Homeostasis and Suppression of Leukemia Journal of Experimental Medicine. 200: 1681-1687. PMID 15611294 DOI: 10.1084/Jem.20041247  0.373
2004 Iwama A, Oguro H, Negishi M, Kato Y, Morita Y, Tsukui H, Ema H, Kamijo T, Katoh-Fukui Y, Koseki H, van Lohuizen M, Nakauchi H. Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1. Immunity. 21: 843-51. PMID 15589172 DOI: 10.1182/Blood.V104.11.1686.1686  0.446
2004 Nakauchi H. Isolation and clonal characterization of hematopoietic and liver stem cells. Cornea. 23. PMID 15448473 DOI: 10.1097/01.Ico.0000136664.18129.4F  0.553
2004 Ojima K, Uezumi A, Miyoshi H, Masuda S, Morita Y, Fukase A, Hattori A, Nakauchi H, Miyagoe-Suzuki Y, Takeda S. Mac-1low early myeloid cells in the bone marrow-derived SP fraction migrate into injured skeletal muscle and participate in muscle regeneration Biochemical and Biophysical Research Communications. 321: 1050-1061. PMID 15358135 DOI: 10.1016/J.Bbrc.2004.07.069  0.427
2004 Suzuki A, Nakauchi H, Taniguchi H. Prospective Isolation of Multipotent Pancreatic Progenitors Using Flow-Cytometric Cell Sorting Diabetes. 53: 2143-2152. PMID 15277399 DOI: 10.2337/Diabetes.53.8.2143  0.546
2004 Miyagi S, Saito T, Mizutani K, Masuyama N, Gotoh Y, Iwama A, Nakauchi H, Masui S, Niwa H, Nishimoto M, Muramatsu M, Okuda A. The Sox-2 regulatory regions display their activities in two distinct types of multipotent stem cells. Molecular and Cellular Biology. 24: 4207-20. PMID 15121842 DOI: 10.1128/Mcb.24.10.4207-4220.2004  0.518
2004 Suzuki A, Zheng YW, Fukao K, Nakauchi H, Taniguchi H. Liver repopulation by c-Met-positive stem/progenitor cells isolated from the developing rat liver. Hepato-Gastroenterology. 51: 423-6. PMID 15086173  0.375
2004 Takano H, Ema H, Sudo K, Nakauchi H. Asymmetric Division and Lineage Commitment at the Level of Hematopoietic Stem Cells: Inference from Differentiation in Daughter Cell and Granddaughter Cell Pairs Journal of Experimental Medicine. 199: 295-302. PMID 14744992 DOI: 10.1084/Jem.20030929  0.531
2004 Ema H, Nakauchi H. Homing to Niche," a new criterion for hematopoietic stem cells? Immunity. 20: 1-2. PMID 14738758 DOI: 10.1016/S1074-7613(04)00002-0  0.5
2004 Sumazaki R, Shiojiri N, Isoyama S, Masu M, Keino-Masu K, Osawa M, Nakauchi H, Kageyama R, Matsui A. Conversion of biliary system to pancreatic tissue in Hes1-deficient mice. Nature Genetics. 36: 83-87. PMID 14702043 DOI: 10.1038/Ng1273  0.353
2004 Maeda A, Iwama A, Eto K, Ema H, Kitamura T, Vestweber D, Nakauchi H. Expression of Endomucin, a CD34-Like Sialomucin, Marks Definitive Hematopoietic Stem Cells throughout Development. Blood. 104: 563-563. DOI: 10.1182/Blood.V104.11.563.563  0.457
2004 Ema H, Kaneda M, Maeda A, Takano H, Nakauchi H. Lymphoid Lineage Restriction in Hematopoietic Stem Cells through Their First Division. Blood. 104: 368-368. DOI: 10.1182/Blood.V104.11.368.368  0.512
2004 Kato Y, Iwama A, Nakauchi H. Selective Activation of STAT5 Unveils Its Role in the Maintenance of Hematopoietic Stem Cells and the Development of Myeloproliferative Disorder. Blood. 104: 3549-3549. DOI: 10.1182/Blood.V104.11.3549.3549  0.504
2004 Takayanagi S, Hiroyama T, Yamazaki S, Iwama A, Nakauchi H. Tmtsp , a Novel Gene Encoding a Cell Surface Protein Highly Specific to Hematopoietic Stem and Endothelial Cells. Blood. 104: 3218-3218. DOI: 10.1182/Blood.V104.11.3218.3218  0.487
2004 Takahashi S, Watanabe N, Ooi J, Tomonari A, Takasugi K, Uchiyama M, Konuma T, Futami M, Yamanishi Y, Takahashi K, Tojo A, Nagamura T, Takahashi TA, Mori T, Okamoto S, ... Nakauchi H, et al. Contribution of T-Cell Reconstitution during the Early Phase after Cord Blood Transplantation to Favorable Clinical Outcomes. Blood. 104: 2227-2227. DOI: 10.1182/Blood.V104.11.2227.2227  0.397
2004 Hamanaka S, Usui J, Takahashi S, Yoshida H, Nagata M, Otsu M, Kaneko S, Nagasawa T, Nakauchi H, Onodera M. 330. Genetic Modification of Murine Embryonic Stem Cells by the Gene Silencing Resistance Retroviral Vector GCDsap Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.272  0.364
2004 Nabekura T, Nakauchi H, Nagasawa T, Onodera M. 255. Potent Cancer Immunotherapy with Dendritic Cells Generated from Genetically Modified Hematopoietic Stem Cells Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.196  0.388
2003 Shibuya K, Shirakawa J, Kameyama T, Honda S, Tahara-Hanaoka S, Miyamoto A, Onodera M, Sumida T, Nakauchi H, Miyoshi H, Shibuya A. CD226 (DNAM-1) Is Involved in Lymphocyte Function–associated Antigen 1 Costimulatory Signal for Naive T Cell Differentiation and Proliferation Journal of Experimental Medicine. 198: 1829-1839. PMID 14676297 DOI: 10.1084/Jem.20030958  0.338
2003 Ema H, Nakauchi H. Self-renewal and lineage restriction of hematopoietic stem cells. Current Opinion in Genetics & Development. 13: 508-512. PMID 14550417 DOI: 10.1016/J.Gde.2003.08.011  0.509
2003 Suzuki A, Nakauchi H, Taniguchi H. In vitro production of functionally mature hepatocytes from prospectively isolated hepatic stem cells. Cell Transplantation. 12: 469-473. PMID 12953920 DOI: 10.3727/000000003108747028  0.439
2003 Yotsumoto K, Okoshi Y, Shibuya K, Yamazaki S, Tahara-Hanaoka S, Honda S, Osawa M, Kuroiwa A, Matsuda Y, Tenen DG, Iwama A, Nakauchi H, Shibuya A. Paired activating and inhibitory immunoglobulin-like receptors, MAIR-I and MAIR-II, regulate mast cell and macrophage activation. The Journal of Experimental Medicine. 198: 223-33. PMID 12874256 DOI: 10.1084/Jem.20021825  0.359
2003 Kojima H, Kanada H, Shimizu S, Kasama E, Shibuya K, Nakauchi H, Nagasawa T, Shibuya A. CD226 mediates platelet and megakaryocytic cell adhesion to vascular endothelial cells. The Journal of Biological Chemistry. 278: 36748-53. PMID 12847109 DOI: 10.1074/Jbc.M300702200  0.347
2003 Migishima F, Oikawa A, Kondo S, Ema H, Morita Y, Nakauchi H, Yokoyama M, Song S, Nishijima M, Okabe M, Shinohara N. Full reconstitution of hematopoietic system by murine umbilical cord blood. Transplantation. 75: 1820-1826. PMID 12811240 DOI: 10.1097/01.Tp.0000065295.99190.03  0.476
2003 Suzuki A, Nakauchi H, Taniguchi H. Glucagon-like peptide 1 (1-37) converts intestinal epithelial cells into insulin-producing cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 5034-5039. PMID 12702762 DOI: 10.1073/Pnas.0936260100  0.324
2003 Suzuki A, Iwama A, Miyashita H, Nakauchi H, Taniguchi H. Role for growth factors and extracellular matrix in controlling differentiation of prospectively isolated hepatic stem cells. Development. 130: 2513-2524. PMID 12702664 DOI: 10.1242/Dev.00459  0.501
2003 Morita Y, Nakauchi H. [Use of FACS for the isolation of stem cells]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 61: 358-62. PMID 12701156  0.367
2003 Fujiki Y, Fukawa K, Kameyama K, Kudo O, Onodera M, Nakamura Y, Yagami K, Shiina Y, Hamada H, Shibuya A, Nakauchi H. Successful multilineage engraftment of human cord blood cells in pigs after in utero transplantation. Transplantation. 75: 916-22. PMID 12698074 DOI: 10.1097/01.Tp.0000057243.12110.7C  0.447
2003 Kunisato A, Chiba S, Nakagami-Yamaguchi E, Kumano K, Saito T, Masuda S, Yamaguchi T, Osawa M, Kageyama R, Nakauchi H, Nishikawa M, Hirai H. HES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivo. Blood. 101: 1777-1783. PMID 12406868 DOI: 10.1182/Blood-2002-07-2051  0.518
2003 Suzuki A, Oyama K, Fukao K, Nakauchi H, Taniguchi H. Establishment of clonal colony-forming assay system for pancreatic stem/progenitor cells. Cell Transplantation. 11: 451-3. PMID 12382672  0.431
2003 Miyashita H, Suzuki A, Fukao K, Nakauchi H, Taniguchi H. Evidence for hepatocyte differentiation from embryonic stem cells in vitro. Cell Transplantation. 11: 429-34. PMID 12382669  0.398
2002 Suzuki A, Nakauchi H. Identification and propagation of liver stem cells Seminars in Cell & Developmental Biology. 13: 455-461. PMID 12468247 DOI: 10.1016/S1084952102001349  0.526
2002 Osawa M, Yamaguchi T, Nakamura Y, Kaneko S, Onodera M, Sawada K, Jegalian A, Wu H, Nakauchi H, Iwama A. Erythroid expansion mediated by the Gfi-1B zinc finger protein: role in normal hematopoiesis Blood. 100: 2769-2777. PMID 12351384 DOI: 10.1182/Blood-2002-01-0182  0.38
2002 Hirasawa R, Shimizu R, Takahashi S, Osawa M, Takayanagi S, Kato Y, Onodera M, Minegishi N, Yamamoto M, Fukao K, Taniguchi H, Nakauchi H, Iwama A. Essential and Instructive Roles of GATA Factors in Eosinophil Development Journal of Experimental Medicine. 195: 1379-1386. PMID 12045236 DOI: 10.1084/Jem.20020170  0.467
2002 Yoriuma H, Nakauchi H. [Self-renewal potential of hematopoietic stem cells]. [Rinsho Ketsueki] the Japanese Journal of Clinical Hematology. 43: 270-3. PMID 12043206  0.343
2002 Sakai Y, Kim DK, Iwasa S, Liang J, Watanabe T, Onodera M, Nakauchi H. Bone marrow chimerism prevents atherosclerosis in arterial walls of mice deficient in apolipoprotein E. Atherosclerosis. 161: 27-34. PMID 11882314 DOI: 10.1016/S0021-9150(01)00614-1  0.345
2002 Iwama A, Osawa M, Hirasawa R, Uchiyama N, Kaneko S, Onodera M, Shibuya K, Shibuya A, Vinson C, Tenen DG, Nakauchi H. Reciprocal Roles for CCAAT/Enhancer Binding Protein (C/EBP) and PU.1 Transcription Factors in Langerhans Cell Commitment Journal of Experimental Medicine. 195: 547-558. PMID 11877478 DOI: 10.1084/Jem.20011465  0.38
2002 Tahara-Hanaoka S, Sudo K, Ema H, Miyoshi H, Nakauchi H. Lentiviral vector-mediated transduction of murine CD34(-) hematopoietic stem cells. Experimental Hematology. 30: 11-17. PMID 11823032 DOI: 10.1016/S0301-472X(01)00761-5  0.515
2002 Suzuki A, Zheng YW, Kaneko S, Onodera M, Fukao K, Nakauchi H, Taniguchi H. Clonal identification and characterization of self-renewing pluripotent stem cells in the developing liver Journal of Cell Biology. 156: 173-184. PMID 11781341 DOI: 10.1083/Jcb.200108066  0.533
2002 Suzuki A, Oyama K, Fukao K, Nakauchi H, Taniguchi H. Establishment of clonal colony-forming assay system for pancreatic stem/progenitor cells. Cell Transplantation. 11: 451-453. DOI: 10.3727/000000002783985765  0.525
2002 Miyashita H, Suzuki A, Fukao K, Nakauchi H, Taniguchi H. Evidence for hepatocyte differentiation from embryonic stem cells in vitro. Cell Transplantation. 11: 429-434. DOI: 10.3727/000000002783985675  0.497
2001 Motohashi T, Nakamura Y, Osawa M, Hiroyama T, Iwama A, Shibuya A, Nakauchi H. Increased cell surface expression of C-terminal truncated erythropoietin receptors in polycythemia European Journal of Haematology. 67: 88-93. PMID 11722595 DOI: 10.1034/J.1600-0609.2001.T01-1-00446.X  0.381
2001 Tokoro Y, Shibuya K, Osawa M, Tahara-Hanaoka S, Iwama A, Kitamura T, Nakauchi H, Shibuya A. Molecular cloning and characterization of mouse Tspan-3, a novel member of the tetraspanin superfamily, expressed on resting dendritic cells. Biochemical and Biophysical Research Communications. 288: 178-183. PMID 11594770 DOI: 10.1006/Bbrc.2001.5742  0.426
2001 Zhou S, Schuetz JD, Bunting KD, Colapietro AM, Sampath J, Morris JJ, Lagutina I, Grosveld GC, Osawa M, Nakauchi H, Sorrentino BP. The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nature Medicine. 7: 1028-34. PMID 11533706 DOI: 10.1038/Nm0901-1028  0.502
2001 Osada H, Doi S, Fukushima T, Nakauchi H, Seki K, Sekiya S. Detection of fetal HPCs in maternal circulation after delivery. Transfusion. 41: 499-503. PMID 11316901 DOI: 10.1046/J.1537-2995.2001.41040499.X  0.307
2001 Suzuki A, Zheng YW, Fukao K, Nakauchi H, Taniguchi H. Hepatic stem/progenitor cells with high proliferative potential in liver organ formation Transplantation Proceedings. 33: 585-586. PMID 11266969 DOI: 10.1016/S0041-1345(00)02153-9  0.419
2001 Kaneko S, Onodera M, Fujiki Y, Nagasawa T, Nakauchi H. Simplified retroviral vector gcsap with murine stem cell virus long terminal repeat allows high and continued expression of enhanced green fluorescent protein by human hematopoietic progenitors engrafted in nonobese diabetic/severe combined immunodeficient mice. Human Gene Therapy. 12: 35-44. PMID 11177540 DOI: 10.1089/104303401450942  0.479
2001 Suzuki A, Zheng Y, Fukao K, Nakauchi H, Taniguchi H. Clonal expansion of hepatic stem/progenitor cells following flow cytometric cell sorting. Cell Transplantation. 10: 393-396. DOI: 10.3727/000000001783986602  0.495
2000 Taniguchi H, Kondo R, Suzuki A, Zheng YW, Takada Y, Fukunaga K, Seino KI, Yuzawa K, Otsuka M, Fukao K, Nakauchi H. Clonogenic Colony-Forming Ability of Flow Cytometrically Isolated Hepatic Progenitor Cells in the Murine Fetal Liver. Cell Transplantation. 9: 697-700. PMID 28880668 DOI: 10.1177/096368970000900517  0.493
2000 Suzuki A, Taniguchi H, Zheng YW, Takada Y, Fukunaga K, Seino K, Yazawa K, Otsuka M, Fukao K, Nakauchi H. Clonal colony formation of hepatic stem/progenitor cells enhanced by embryonic fibroblast conditioning medium. Transplantation Proceedings. 32: 2328-2330. PMID 11120186 DOI: 10.1016/S0041-1345(00)01685-7  0.477
2000 Suzuki A, Zheng YW, Kondo R, Kusakabe M, Takada Y, Fukao K, Nakauchi H, Taniguchi H. Flow-cytometric separation and enrichment of hepatic progenitor cells in the developing mouse liver Hepatology. 32: 1230-1239. PMID 11093729 DOI: 10.1053/Jhep.2000.20349  0.464
2000 Ema H, Takano H, Sudo K, Nakauchi H. In vitro self-renewal division of hematopoietic stem cells. Journal of Experimental Medicine. 192: 1281-1288. PMID 11067877 DOI: 10.1084/Jem.192.9.1281  0.511
2000 Sudo K, Ema H, Morita Y, Nakauchi H. Age-associated characteristics of murine hematopoietic stem cells. Journal of Experimental Medicine. 192: 1273-1280. PMID 11067876 DOI: 10.1084/Jem.192.9.1273  0.504
2000 Motohashi T, Miyoshi S, Osawa M, Eyre HJ, Sutherland GR, Matsuda Y, Nakamura Y, Shibuya A, Iwama A, Nakauchi H. Molecular cloning and chromosomal mapping of a novel five-span transmembrane protein gene, M83. Biochemical and Biophysical Research Communications. 276: 244-250. PMID 11006113 DOI: 10.1006/Bbrc.2000.3409  0.342
2000 Tahara-Hanaoka S, Ushijima Y, Tarui H, Wada M, Hara T, Imanishi S, Yamaguchi T, Hattori T, Nakauchi H, Koito A. Differential Level in Co‐Down‐Modulation of CD4 and CXCR4 Primed by HIV‐1 gp120 in Response to Phorbol Ester, PMA, among HIV‐1 Isolates Microbiology and Immunology. 44: 489-498. PMID 10941932 DOI: 10.1111/J.1348-0421.2000.Tb02524.X  0.317
2000 Miyoshi H, Ehashi T, Ema H, Hsu HC, Nakauchi H, Ohshima N. Long-term culture of fetal liver cells using a three-dimensional porous polymer substrate Asaio Journal. 46: 397-402. PMID 10926134 DOI: 10.1097/00002480-200007000-00005  0.306
2000 Fujiki Y, Onodera M, Yamaguchi T, Osawa M, Sudo K, Hamada H, Ema H, Shibuya A, Takiguchi M, Kubo T, Nakauchi H. Dominant expansion of human T cells in non-obese diabetic/severe combined immunodeficiency mice implanted with human bone fragments. Experimental Hematology. 28: 792-801. PMID 10907641 DOI: 10.1016/S0301-472X(00)00178-8  0.41
2000 Watanabe N, Yamaguchi T, Akimoto Y, Rattner JB, Hirano H, Nakauchi H. Induction of M-phase arrest and apoptosis after HIV-1 Vpr expression through uncoupling of nuclear and centrosomal cycle in HeLa cells. Experimental Cell Research. 258: 261-269. PMID 10896777 DOI: 10.1006/Excr.2000.4908  0.358
2000 Hiroyama T, Iwama A, Morita Y, Nakamura Y, Shibuya A, Nakauchi H. Molecular Cloning and Characterization of CRLM-2, a Novel Type I Cytokine Receptor Preferentially Expressed in Hematopoietic Cells ☆ ☆☆ Biochemical and Biophysical Research Communications. 272: 224-229. PMID 10872831 DOI: 10.1006/Bbrc.2000.2764  0.325
2000 Taniguchi H, Suzuki A, Zheng Y, Kondo R, Takada Y, Fukunaga K, Seino K, Yuzawa K, Otsuka M, Fukao K, Nakauchi H. Usefulness of flow-cytometric cell sorting for enrichment of hepatic stem and progenitor cells in the liver Transplantation Proceedings. 32: 249-251. PMID 10715407 DOI: 10.1016/S0041-1345(99)00947-1  0.443
2000 Kaneta M, Osawa M, Osawa M, Sudo K, Nakauchi H, Farr AG, Takahama Y. A Role for Pref-1 and HES-1 in Thymocyte Development Journal of Immunology. 164: 256-264. PMID 10605019 DOI: 10.4049/Jimmunol.164.1.256  0.44
2000 Hsu H, Ema H, Osawa M, Nakamura Y, Suda T, Nakauchi H. Hematopoietic stem cells express Tie-2 receptor in the murine fetal liver. Blood. 96: 3757-3762. DOI: 10.1182/Blood.V96.12.3757  0.532
2000 Ema H, Nakauchi H. Expansion of hematopoietic stem cells in the developing liver of a mouse embryo Blood. 95: 2284-2288. DOI: 10.1182/Blood.V95.7.2284  0.433
2000 Nakauchi H, Morita Y, Sudo K, Ema H. Identification of CD34lo/−kit+sca+lin− cells in HOECHST33342 side population (Sp) Of the mouse bone marrow cells Experimental Hematology. 28: 112. DOI: 10.1016/S0301-472X(00)00433-1  0.431
2000 Almeida-Porada G, Crapnell K, Porada C, Benoit B, Nakauchi H, Quesenberry P, Zanjani E. In vivo hematopoietic potential of human neuronal stem cells Experimental Hematology. 28: 61. DOI: 10.1016/S0301-472X(00)00278-2  0.464
2000 Nakauchi H, Osawa M, Sudo K, Ema H. Isolation and Characterization of CD34-Low/Negative Mouse Hematopoietic Stem Cells The Keio Journal of Medicine. 48: 95-103. DOI: 10.1007/978-4-431-68506-7_8  0.513
1999 Tun T, Miyoshi H, Ema H, Nakauchi H, Ohshima N. New type of matrix support for bone marrow cell cultures: in vitro culture and in vivo transplantation experiments. Asaio Journal. 46: 522-526. PMID 11016499 DOI: 10.1097/00002480-200009000-00002  0.395
1999 Shibuya K, Lanier LL, Phillips JH, Ochs HD, Shimizu K, Nakayama E, Nakauchi H, Shibuya A. Physical and functional association of LFA-1 with DNAM-1 adhesion molecule. Immunity. 11: 615-23. PMID 10591186 DOI: 10.1016/S1074-7613(00)80136-3  0.376
1999 Kim DK, Fujiki Y, Fukushima T, Ema H, Shibuya A, Nakauchi H. Comparison of hematopoietic activities of human bone marrow and umbilical cord blood CD34 positive and negative cells. Stem Cells. 17: 286-294. PMID 10527463 DOI: 10.1002/Stem.170286  0.499
1999 Yamaguchi T, Watanabe N, Nakauchi H, Koito A. Human immunodeficiency virus type 1 Vpr modifies cell proliferation via multiple pathways. Microbiology and Immunology. 43: 437-447. PMID 10449250 DOI: 10.1111/J.1348-0421.1999.Tb02427.X  0.428
1999 Nakauchi H, Takano H, Ema H, Osawa M. Further characterization of CD34-low/negative mouse hematopoietic stem cells Annals of the New York Academy of Sciences. 872: 57-70. PMID 10372111 DOI: 10.1111/J.1749-6632.1999.Tb08453.X  0.434
1999 Apostolou I, Takahama Y, Belmant C, Kawano T, Huerre M, Marchal G, Cui J, Taniguchi M, Nakauchi H, Fournié J-, Kourilsky P, Gachelin G. Murine natural killer cells contribute to the granulomatous reaction caused by mycobacterial cell walls Proceedings of the National Academy of Sciences of the United States of America. 96: 5141-5146. PMID 10220432 DOI: 10.1073/Pnas.96.9.5141  0.422
1999 Taniguchi H, Kondo R, Suzuki A, Zheng Y, Ito S, Takada Y, Fukunaga K, Seino K, Yuzawa K, Otsuka M, Fukao K, Yoshiki A, Kusakabe M, Nakauchi H. Evidence for the presence of hepatic stem cells in the murine fetal liver. Transplantation Proceedings. 31: 454. PMID 10083186 DOI: 10.1016/S0041-1345(98)01704-7  0.409
1999 Matsuda K, Koguma M, Okuyama R, Nakazawa T, Matsuzaki Y, Nakauchi H, Yanai N, Terasaki T, Obinata M. A novel stromal cell-dependent B lymphoid stem-like cell line that induces immunoglobulin gene rearrangement. Journal of Biochemistry. 125: 602-612. PMID 10050050 DOI: 10.1093/Oxfordjournals.Jbchem.A022326  0.416
1998 Muto A, Hoshino H, Madisen L, Yanai N, Obinata M, Karasuyama H, Hayashi N, Nakauchi H, Yamamoto M, Groudine M, Igarashi K. Identification of Bach2 as a B-cell-specific partner for small maf proteins that negatively regulate the immunoglobulin heavy chain gene 3' enhancer. The Embo Journal. 17: 5734-43. PMID 9755173 DOI: 10.1093/Emboj/17.19.5734  0.395
1998 Nakauchi H. Hematopoietic stem cells: are they CD34-positive or CD34-negative? Nature Medicine. 4: 1009-1010. PMID 9734390 DOI: 10.1038/1996  0.471
1998 Fukushima T, Sumazaki R, Koike K, Tsuchida M, Matsui A, Nakauchi H. Multicolor flow-cytometric, morphologic, and clonogenic analysis of marrow CD10-positive cells in children with leukemia in remission or nonmalignant diseases Journal of Pediatric Hematology Oncology. 20: 222-228. PMID 9628433 DOI: 10.1097/00043426-199805000-00007  0.366
1997 Takahama Y, Tokoro Y, Sugawara T, Negishi I, Nakauchi H. Pertussis toxin can replace T cell receptor signals that induce positive selection of CD8 T cells. European Journal of Immunology. 27: 3318-3331. PMID 9464820 DOI: 10.1002/Eji.1830271231  0.339
1997 Sohda S, Arinami T, Hamada H, Nakauchi H, Hamaguchi H, Kubo T. The Proportion of Fetal Nucleated Red Blood Cells in Maternal Blood: Stimation by FACS Analysis Prenatal Diagnosis. 17: 743-752. PMID 9267898 DOI: 10.1002/(Sici)1097-0223(199708)17:8<743::Aid-Pd144>3.0.Co;2-3  0.315
1997 Taniguchi H, Sugioka A, Nakauchi H, Fukao K. Characterization of hematopoietic stem cells in the adult liver Transplantation Proceedings. 29: 1212-1213. PMID 9123278 DOI: 10.1016/S0041-1345(96)00555-6  0.443
1997 Nishimura Y, Hirabayashi Y, Matsuzaki Y, Musette P, Ishii A, Nakauchi H, Inoue T, Yonehara S. In vivo analysis of Fas antigen-mediated apoptosis: effects of agonistic anti-mouse Fas mAb on thymus, spleen and liver. International Immunology. 9: 307-316. PMID 9040012 DOI: 10.1093/Intimm/9.2.307  0.336
1997 Matsuzaki Y, Nakayama KI, Nakayama K, Tomita T, Isoda M, Loh DY, Nakauchi H. Role of bcl-2 in the development of lymphoid cells from the hematopoietic stem cell Blood. 89: 853-862. PMID 9028316  0.425
1997 Matsuzaki Y, Nakayama K, Nakayama K, Tomita T, Isoda M, Loh DY, Nakauchi H. Role of bcl-2 in the Development of Lymphoid Cells From the Hematopoietic Stem Cell Blood. 89: 853-862. DOI: 10.1182/Blood.V89.3.853  0.512
1996 Kawachi Y, Otsuka F, Nakauchi H. Characterization of the mouse CD8 beta chain-encoding gene promoter region Immunogenetics. 44: 358-365. PMID 8781121 DOI: 10.1007/Bf02602780  0.334
1996 Osawa M, Hanada K, Hamada H, Nakauchi H. Long-Term Lymphohematopoietic Reconstitution by a Single CD34-Low/Negative Hematopoietic Stem Cell Science. 273: 242-245. PMID 8662508 DOI: 10.1126/Science.273.5272.242  0.5
1996 Shimizu R, Komatsu N, Nakamura Y, Nakauchi H, Nakabeppu Y, Miura Y. Role of c-jun in the inhibition of erythropoietin receptor-mediated apoptosis Biochemical and Biophysical Research Communications. 222: 1-6. PMID 8630050 DOI: 10.1006/Bbrc.1996.0688  0.329
1996 Taniguchi H, Toyoshima T, Fukao K, Nakauchi H. Presence of hematopoietic stem cells in the adult liver. Nature Medicine. 2: 198-203. PMID 8574965 DOI: 10.1038/Nm0296-198  0.466
1996 Nakamura Y, Tokumoto Y, Nakauchi H. Role of a truncated erythropoietin receptor for erythroid differentiation. Biochemical and Biophysical Research Communications. 218: 205-209. PMID 8573132 DOI: 10.1006/Bbrc.1996.0036  0.339
1995 Park SY, Saijo K, Takahashi T, Osawa M, Arase H, Hirayama N, Miyake K, Nakauchi H, Shirasawa T, Saito T. Developmental defects of lymphoid cells in Jak3 kinase-deficient mice. Immunity. 3: 771-82. PMID 8777722 DOI: 10.1016/1074-7613(95)90066-7  0.416
1995 Shibuya A, Nagayoshi K, Nakamura K, Nakauchi H. Lymphokine requirement for the generation of natural killer cells from CD34+ hematopoietic progenitor cells Blood. 85: 3538-3546. DOI: 10.1182/Blood.V85.12.3538.Bloodjournal85123538  0.382
1994 Nohara K, Nakauchi H, Spiegel S. Glycosphingolipids of rat T cells. Predominance of asialo-GM1 and GD1c. Biochemistry. 33: 4661-6. PMID 8161523 DOI: 10.1021/Bi00181A601  0.386
1994 Nakayama KI, Nakayama K, Negishi I, Kuida K, Louie MC, Kanagawa O, Nakauchi H, Loh DY. Requirement for CD8 β chain in positive selection of CD8-lineage T cells Science. 263: 1131-1133. PMID 8108731 DOI: 10.1126/Science.8108731  0.373
1994 Kajii E, Umenishi F, Nakauchi H, Ikemoto S. Expression of Rh blood group gene transcripts in human leukocytes. Biochemical and Biophysical Research Communications. 202: 1497-504. PMID 8060332 DOI: 10.1006/Bbrc.1994.2100  0.364
1993 Aiba Y, Mazda O, Matsuzaki Y, Nakauchi H, Muramatsu S, Katsura Y. Clonal deletion of thymic mature T cells induced by staphylococcal enterotoxin B in murine fetal thymus organ culture European Journal of Immunology. 23: 815-819. PMID 8458372 DOI: 10.1002/Eji.1830230407  0.357
1993 Hitoshi Y, Sonoda E, Kikuchi Y, Yonehara S, Nakauchi H, Takatsu K. IL-5 receptor positive B cells, but not eosinophils, are functionally and numerically influenced in mice carrying the X-linked immune defect International Immunology. 5: 1183-1190. PMID 8241057 DOI: 10.1093/Intimm/5.9.1183  0.336
1993 Matsuzaki Y, Gyotoku JI, Ogawa M, Nishikawa SI, Katsura Y, Gachelin G, Nakauchi H. Characterization of c-kit positive intrathymic stem cells that are restricted to lymphoid differentiation. Journal of Experimental Medicine. 178: 1283-1292. PMID 7690832 DOI: 10.1084/Jem.178.4.1283  0.442
1993 Gunji Y, Nakamura M, Osawa H, Nagayoshi K, Nakauchi H, Miura Y, Yanagisawa M, Suda T. Human primitive hematopoietic progenitor cells are more enriched in KITlow cells than in KIThigh cells Blood. 82: 3283-3289. DOI: 10.1182/Blood.V82.11.3283.Bloodjournal82113283  0.454
1993 Shibuya A, Kojima H, Shibuya K, Nagayoshi K, Nagasawa T, Nakauchi H. Enrichment of interleukin-2-responsive natural killer progenitors in human bone marrow Blood. 81: 1819-1826. DOI: 10.1182/Blood.V81.7.1819.Bloodjournal8171819  0.359
1993 Okada S, Nagayoshi K, Nakauchi H, Nishikawa SI, Miura Y, Suda T. Sequential analysis of hematopoietic reconstitution achieved by transplantation of hematopoietic stem cells Blood. 81: 1720-1725. DOI: 10.1182/Blood.V81.7.1720.Bloodjournal8171720  0.506
1993 Nishikawa M, Ozawa K, Tojo A, Yoshikubo T, Okano A, Tani K, Ikebuchi K, Nakauchi H, Asano S. Changes in hematopoiesis-supporting ability of C3H10T1/2 mouse embryo fibroblasts during differentiation Blood. 81: 1184-1192. DOI: 10.1182/Blood.V81.5.1184.Bloodjournal8151184  0.468
1993 Onishi M, Nagayoshi K, Kitamura K, Hirai H, Takaku F, Nakauchi H. CD4dull+ hematopoietic progenitor cells in murine bone marrow Blood. 81: 3217-3225. DOI: 10.1182/Blood.V81.12.3217.3217  0.519
1992 Kawakami Y, Yamaoka T, Hirochika R, Yamashita K, Itakura M, Nakauchi H. Somatic gene therapy for diabetes with an immunological safety system for complete removal of transplanted cells. Diabetes. 41: 956-961. PMID 1628770 DOI: 10.2337/Diab.41.8.956  0.416
1992 Tanabe M, Karaki S, Takiguchi M, Nakauchi H. Antigen recognition by the T cell receptor is enhanced by CD8 α-chain binding to the α3 domain of MHC class I molecules, not by signaling via the cytoplasmic domain of CD8α International Immunology. 4: 147-152. PMID 1622893 DOI: 10.1093/Intimm/4.2.147  0.306
1992 Takahashi K, Nakata M, Tanaka T, Adachi H, Nakauchi H, Yagita H, Okumura K. CD4 and CD8 regulate interleukin 2 responses of T cells. Proceedings of the National Academy of Sciences of the United States of America. 89: 5557-5561. PMID 1608966 DOI: 10.1073/Pnas.89.12.5557  0.319
1992 Nakamura Y, Komatsu N, Nakauchi H. A Truncated Erythropoietin Receptor That Fails to Prevent Programmed Cell Death of Erythroid Cells Science. 257: 1138-1141. PMID 1324524 DOI: 10.1126/Science.257.5073.1138  0.38
1992 Gunji Y, Nakamura M, Hagiwara T, Hayakawa K, Matsushita H, Osawa H, Nagayoshi K, Nakauchi H, Yanagisawa M, Miura Y. Expression and function of adhesion molecules on human hematopoietic stem cells: CD34+ LFA-1- cells are more primitive than CD34+ LFA-1+ cells. Blood. 80: 429-436. DOI: 10.1182/Blood.V80.2.429.Bloodjournal802429  0.394
1992 Okada S, Nakauchi H, Nagayoshi K, Nishikawa SI, Miura Y, Suda T. In vivo and in vitro stem cell function of c-kit- and Sca-1-positive murine hematopoietic cells. Blood. 80: 3044-3050. DOI: 10.1182/Blood.V80.12.3044.3044  0.485
1992 Muroi K, Suda T, Nojiri H, Ema H, Amemiya Y, Miura Y, Nakauchi H, Singhal A, Hakomori SI. Reactivity profiles of leukemic myeloblasts with monoclonal antibodies directed to sialosyl-Le(x) and other lacto-series type 2 chain antigens:absence of reactivity with normal hematopoietic progenitor cells. Blood. 79: 713-719. DOI: 10.1182/Blood.V79.3.713.713  0.38
1991 Ohara A, Suda T, Tokuyama N, Suda J, Nakayama KI, Miura Y, Nishikawa SI, Nakauchi H. Generation of B lymphocytes from a single hemopoietic progenitor cell in vitro. International Immunology. 3: 703-709. PMID 1911541 DOI: 10.1093/Intimm/3.7.703  0.504
1991 Ema H, Suda T, Nakauchi H, Nakamura Y, Iwama A, Imagawa S, Akutsu M, Kano Y, Kato S, Yabe M, Yoshida M, Sakamoto S, Amemiya Y, Miura Y. Multipotent and committed CD34+ cells in bone marrow transplantation. Japanese Journal of Cancer Research. 82: 547-552. PMID 1712005 DOI: 10.1111/J.1349-7006.1991.Tb01885.X  0.409
1991 Okada S, Nakauchi H, Nagayoshi K, Nishikawa S, Miura Y, Suda T. Enrichment and characterization of murine hematopoietic stem cells that express c-kit molecule Blood. 78: 1706-1712. DOI: 10.1182/Blood.V78.7.1706.Bloodjournal7871706  0.452
1991 Tsunoda JI, Okada S, Suda J, Nagayoshi K, Nakauchi H, Hatake K, Miura Y, Suda T. In vivo stem cell function of interleukin-3-induced blast cells. Blood. 78: 318-322. DOI: 10.1182/Blood.V78.2.318.318  0.533
1991 Gunji Y, Sudo T, Suda J, Yamaguchi Y, Nakauchi H, Nishikawa S, Yanai N, Obinata M, Yanagisawa M, Miura Y. Support of Early B-Cell Differentiation in Mouse Fetal Liver by Stromal Cells and Interleukin-7 Blood. 77: 2612-2617. DOI: 10.1182/Blood.V77.12.2612.2612  0.409
1990 Kanagawa O, Nakauchi H, Sekaly RP, Maeda K, Takagaki Y. Expression and function of the tranfected CD8α chain in murine T cell hybridomas International Immunology. 2: 957-964. PMID 2127694 DOI: 10.1093/Intimm/2.10.957  0.401
1990 Ema H, Suda T, Nagayoshi K, Miura Y, Civin C, Nakauchi H. Target cells for granulocyte colony-stimulating factor, interleukin-3, and interleukin-5 in differentiation pathways of neutrophils and eosinophils Blood. 76: 1956-1961. DOI: 10.1182/Blood.V76.10.1956.Bloodjournal76101956  0.345
1990 Ema H, Suda T, Miura Y, Nakauchi H. Colony formation of clone-sorted human hematopoietic progenitors Blood. 75: 1941-1946. DOI: 10.1182/Blood.V75.10.1941.Bloodjournal75101941  0.387
1989 Nishikawa S-, Hayashi S-, Ogawa M, Kunisada T, Nishikawa S, Sudo T, Nakauchi H, Suda T. Control of cell growth and differentiation during early B-cell development by stromal cell molecules. Cold Spring Harbor Symposia On Quantitative Biology. 54: 171-174. PMID 2639751 DOI: 10.1101/Sqb.1989.054.01.021  0.428
1989 Takei M, Kang H, Tomura K, Ikeda E, Karasaki M, Nakauchi H, Okumura K, Sawada S. Expression of Leu M1 antigen on a monoclonal B cell line established from a patient with rheumatoid arthritis. Immunology Letters. 23: 43-47. PMID 2575080 DOI: 10.1016/0165-2478(89)90153-3  0.362
1989 Kurihara N, Suda T, Miura Y, Nakauchi H, Kodama H, Hiura K, Hakeda Y, Kumegawa M. Generation of osteoclasts from isolated hematopoietic progenitor cells. Blood. 74: 1295-1302. DOI: 10.1182/Blood.V74.4.1295.1295  0.46
1987 Nakauchi H, Tagawa M, Nolan GP, Herzenberg LA. Isolation and characterization of the gene for the murine T cell differentiation antigen and immunoglobulin-related molecule, Lyt-2. Nucleic Acids Research. 15: 4337-47. PMID 3495785 DOI: 10.1093/Nar/15.10.4337  0.522
1987 Nakauchi H, Shinkai Y, Okumura K. Molecular cloning of Lyt-3, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to immunoglobulin and T-cell receptor variable and joining regions. Proceedings of the National Academy of Sciences of the United States of America. 84: 4210-4214. PMID 3035575 DOI: 10.1073/Pnas.84.12.4210  0.311
1986 Tagawa M, Nakauchi H, Herzenberg LA, Nolan GP. Formal proof that different-size Lyt-2 polypeptides arise from differential splicing and post-transcriptional regulation. Proceedings of the National Academy of Sciences of the United States of America. 83: 3422-6. PMID 3085089 DOI: 10.1073/Pnas.83.10.3422  0.473
1985 Nakauchi H, Nolan GP, Hsu C, Huang HS, Kavathas P, Herzenberg LA. Molecular cloning of Lyt-2, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to its human counterpart, Leu-2/T8, and to immunoglobulin variable regions. Proceedings of the National Academy of Sciences of the United States of America. 82: 5126-30. PMID 3927298 DOI: 10.1073/Pnas.82.15.5126  0.454
1982 Nakahara K, Ōhashi T, Ichimaru M, Amagasaki T, Shimoyama M, Nakauchi H, Okumura K. Analyses of adult T-cell leukemia using the monoclonal (anti-Leu-1, anti-Leu-2a, and anti-Leu-3a) and heterologous anti-glycolipid (anti-asialo GM1) antibodies. Clinical Immunology and Immunopathology. 25: 43-52. PMID 6983941 DOI: 10.1016/0090-1229(82)90163-5  0.361
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