Insoo Hyun, PhD - Publications

Affiliations: 
2003-2021 Bioethics and School of Medicine Case Western Reserve University, Cleveland Heights, OH, United States 
 2019-2022 Bioethics Harvard Medical School 
 2021- Museum of Science, Boston 
Website:
https://bioethics.hms.harvard.edu/faculty-staff/insoo-hyun

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Hyun I. Dynamic models of human development and concepts of the individual. Cell. 187: 3220-3223. PMID 38906096 DOI: 10.1016/j.cell.2024.05.028  0.315
2023 Hyun I. New monkey embryo models-it's getting complicated. Cell Stem Cell. 30: 339-340. PMID 37028398 DOI: 10.1016/j.stem.2023.03.014  0.343
2022 Hyun I. Stem cell ethics and policy: What's old is new again. Med (New York, N.Y.). 3: 820-823. PMID 36495862 DOI: 10.1016/j.medj.2022.11.008  0.445
2022 Johnston J, Hyun I, Neuhaus CP, Maschke KJ, Marshall P, Craig KP, Matthews MM, Drolet K, Greely HT, Hill LR, Hinterberger A, Hurley EA, Kesterson R, Kimmelman J, King NMP, et al. Clarifying the Ethics and Oversight of Chimeric Research. The Hastings Center Report. S2-S23. PMID 36484509 DOI: 10.1002/hast.1427  0.533
2022 Marshall P, Craig KP, Hyun I. Moral Status and the Oversight of Research Involving Chimeric Animals. The Hastings Center Report. S41-S45. PMID 36484507 DOI: 10.1002/hast.1431  0.45
2022 Hyun I, Scharf-Deering JC, Sullivan S, Aach JD, Arlotta P, Baum ML, Church GM, Goldenberg A, Greely HT, Khoshakhlagh P, Kohman RE, Lopes M, Lowenthal C, Lu A, Ng AHM, et al. How collaboration between bioethicists and neuroscientists can advance research. Nature Neuroscience. PMID 36258039 DOI: 10.1038/s41593-022-01187-2  0.353
2021 MacDuffie KE, Hyun I, Krogen MM, Dempsey JC, Murry CE, Copp AJ, Glass IA, Doherty D. Rescuing human fetal tissue research in the United States: A call for additional regulatory reform. Stem Cell Reports. PMID 34822773 DOI: 10.1016/j.stemcr.2021.10.016  0.315
2021 Hyun I, Clayton EW, Cong Y, Fujita M, Goldman SA, Hill LR, Monserrat N, Nakauchi H, Pedersen RA, Rooke HM, Takahashi J, Knoblich JA. ISSCR guidelines for the transfer of human pluripotent stem cells and their direct derivatives into animal hosts. Stem Cell Reports. PMID 34048695 DOI: 10.1016/j.stemcr.2021.05.005  0.517
2021 Lovell-Badge R, Anthony E, Barker RA, Bubela T, Brivanlou AH, Carpenter M, Charo RA, Clark A, Clayton E, Cong Y, Daley GQ, Fu J, Fujita M, Greenfield A, Goldman SA, ... ... Hyun I, et al. ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update. Stem Cell Reports. PMID 34048692 DOI: 10.1016/j.stemcr.2021.05.012  0.52
2021 Hyun I, Bredenoord AL, Briscoe J, Klipstein S, Tan T. Human embryo research beyond the primitive streak. Science (New York, N.Y.). 371: 998-1000. PMID 33674483 DOI: 10.1126/science.abf3751  0.416
2020 Garreta E, Kamm RD, Chuva de Sousa Lopes SM, Lancaster MA, Weiss R, Trepat X, Hyun I, Montserrat N. Rethinking organoid technology through bioengineering. Nature Materials. PMID 33199860 DOI: 10.1038/s41563-020-00804-4  0.338
2020 Hyun I, Scharf-Deering JC, Lunshof JE. Ethical Issues Related to Brain Organoid Research. Brain Research. 146653. PMID 32017900 DOI: 10.1016/J.Brainres.2020.146653  0.548
2020 Hyun I, Munsie M, Pera MF, Rivron NC, Rossant J. Toward Guidelines for Research on Human Embryo Models Formed from Stem Cells. Stem Cell Reports. PMID 31951813 DOI: 10.1016/J.Stemcr.2019.12.008  0.573
2019 Hyun I. Ethical considerations for human-animal neurological chimera research: mouse models and beyond. The Embo Journal. e103331. PMID 31602659 DOI: 10.15252/Embj.2019103331  0.517
2019 De Los Angeles A, Hyun I, Latham SR, Elsworth JD, Redmond DE. Human-Monkey Chimeras for Modeling Human Disease: Opportunities and Challenges. Methods in Molecular Biology (Clifton, N.J.). 2005: 221-231. PMID 31175656 DOI: 10.1007/978-1-4939-9524-0_15  0.545
2019 Hyun I. Ethical Standards for Chimera Research Oversight. Methods in Molecular Biology (Clifton, N.J.). 2005: 165-171. PMID 31175652 DOI: 10.1007/978-1-4939-9524-0_11  0.584
2019 Hyun I. Informed Consent Issues for Cell Donors. Methods in Molecular Biology (Clifton, N.J.). 2005: 67-74. PMID 31175646 DOI: 10.1007/978-1-4939-9524-0_5  0.546
2019 Sample M, Boulicault M, Allen C, Bashir R, Hyun I, Levis M, Lowenthal C, Mertz D, Montserrat N, Palmer MJ, Saha K, Zartman J. Multi-cellular engineered living systems: building a community around responsible research on emergence. Biofabrication. PMID 31158828 DOI: 10.1088/1758-5090/Ab268C  0.393
2018 Rivron N, Pera M, Rossant J, Martinez Arias A, Zernicka-Goetz M, Fu J, van den Brink S, Bredenoord A, Dondorp W, de Wert G, Hyun I, Munsie M, Isasi R. Debate ethics of embryo models from stem cells. Nature. 564: 183-185. PMID 30542177 DOI: 10.1038/D41586-018-07663-9  0.587
2018 De Los Angeles A, Hyun I, Latham S, Elsworth J, Redmond E. Human-Monkey Chimeras For Modeling Human Disease: Opportunities and Challenges. Stem Cells and Development. PMID 30319057 DOI: 10.1089/Scd.2018.0162  0.539
2018 Farahany NA, Greely HT, Hyman S, Koch C, Grady C, Pașca SP, Sestan N, Arlotta P, Bernat JL, Ting J, Lunshof JE, Iyer EPR, Hyun I, Capestany BH, Church GM, et al. The ethics of experimenting with human brain tissue. Nature. 556: 429-432. PMID 29691509 DOI: 10.1038/D41586-018-04813-X  0.308
2018 Ogbogu U, Zarzeczny A, Baltz J, Bedford P, Du J, Hyun I, Jaafar Y, Jurisicova A, Kleiderman E, Koukio Y, Knoppers BM, Leader A, Master Z, Nguyen MT, Noohi F, et al. Research on Human Embryos and Reproductive Materials: Revisiting Canadian Law and Policy. Healthcare Policy = Politiques De Sante. 13: 10-19. PMID 29595433 DOI: 10.12927/Hcpol.2018.25401  0.491
2018 Hyun I. The Ethics of Chimera Creation in Stem Cell Research Stem Cell Reports. 4: 235-239. DOI: 10.1007/S40778-018-0136-6  0.624
2017 Hyun I, Osborn C. Query the merits of embryo editing for reproductive research now. Nature Biotechnology. 35: 1023-1025. PMID 29121025 DOI: 10.1038/Nbt.4000  0.426
2017 Hurlbut JB, Hyun I, Levine AD, Lovell-Badge R, Lunshof JE, Matthews KRW, Mills P, Murdoch A, Pera MF, Scott CT, Tizzard J, Warnock M, Zernicka-Goetz M, Zhou Q, Zoloth L. Revisiting the Warnock rule. Nature Biotechnology. 35: 1029-1042. PMID 29121021 DOI: 10.1038/Nbt.4015  0.377
2017 Hyun I. Engineering Ethics and Self-Organizing Models of Human Development: Opportunities and Challenges. Cell Stem Cell. PMID 28943028 DOI: 10.1016/J.Stem.2017.09.002  0.37
2017 Munsie M, Hyun I, Sugarman J. Ethical issues in human organoid and gastruloid research. Development (Cambridge, England). 144: 942-945. PMID 28292838 DOI: 10.1242/Dev.140111  0.521
2017 Bredenoord AL, Hyun I. Ethics of stem cell-derived gametes made in a dish: fertility for everyone? Embo Molecular Medicine. PMID 28279974 DOI: 10.15252/Emmm.201607291  0.505
2017 Hyun I. Bioethics: Democracy in vitro. Nature. 541: 462-463. PMID 28128248 DOI: 10.1038/541462A  0.493
2016 Hyun I. Illusory fears must not stifle chimaera research. Nature. 537: 281. PMID 27629603 DOI: 10.1038/537281A  0.416
2016 Hyun I. What's Wrong with Human/Nonhuman Chimera Research? Plos Biology. 14: e1002535. PMID 27574863 DOI: 10.1371/Journal.Pbio.1002535  0.519
2016 Kimmelman J, Hyun I, Benvenisty N, Caulfield T, Heslop HE, Murry CE, Sipp D, Studer L, Sugarman J, Daley GQ. Policy: Global standards for stem-cell research. Nature. 533: 311-3. PMID 27193661 DOI: 10.1038/533311A  0.558
2016 Daley GQ, Hyun I, Apperley JF, Barker RA, Benvenisty N, Bredenoord AL, Breuer CK, Caulfield T, Cedars MI, Frey-Vasconcells J, Heslop HE, Jin Y, Lee RT, McCabe C, Munsie M, et al. Setting Global Standards for Stem Cell Research and Clinical Translation: The 2016 ISSCR Guidelines. Stem Cell Reports. PMID 27185282 DOI: 10.1016/J.Stemcr.2016.05.001  0.551
2016 Kimmelman J, Heslop HE, Sugarman J, Studer L, Benvenisty N, Caulfield T, Hyun I, Murry CE, Sipp D, Daley GQ. New ISSCR guidelines: clinical translation of stem cell research. Lancet (London, England). PMID 27179752 DOI: 10.1016/S0140-6736(16)30390-7  0.537
2015 Hyun I. From naïve pluripotency to chimeras: a new ethical challenge? Development. 142: 6-8. PMID 25516963 DOI: 10.1242/Dev.119206  0.543
2015 Ijaz S, Hyun I. Somatic Cell Nuclear Transfer: the Promise and the Perils Stem Cell Reports. 1: 215-218. DOI: 10.1007/S40778-015-0021-5  0.545
2014 Munsie M, Hyun I. A question of ethics: selling autologous stem cell therapies flaunts professional standards. Stem Cell Research. 13: 647-653. PMID 24857592 DOI: 10.1016/J.Scr.2014.04.014  0.437
2014 Hyun I. Policy: Regulate embryos made for research Nature. 509: 27-28. PMID 24784200 DOI: 10.1038/509027A  0.397
2013 Hyun I. Therapeutic hope, spiritual distress, and the problem of stem cell tourism Cell Stem Cell. 12: 505-507. PMID 23642359 DOI: 10.1016/J.Stem.2013.04.010  0.412
2013 Haimes E, Skene L, Ballantyne AJ, Caulfield T, Goldstein LS, Hyun I, Kimmelman J, Robert JS, Roxland BE, Scott CT, Solbakk JH, Sugarman J, Taylor PL, Testa G. Position statement on the provision and procurement of human eggs for stem cell research. Cell Stem Cell. 12: 285-91. PMID 23472870 DOI: 10.1016/J.Stem.2013.02.002  0.544
2011 Hyun I. Moving human SCNT research forward ethically. Cell Stem Cell. 9: 295-297. PMID 21982229 DOI: 10.1016/J.Stem.2011.08.001  0.596
2011 Hyun I, Tesar P. Stem cells: Cloning advance calls for careful regulation Nature. 478: 36-37. PMID 21979034 DOI: 10.1038/478036C  0.535
2010 Hyun I. Allowing innovative stem cell-based therapies outside of clinical trials: ethical and policy challenges. Journal of Law Medicine & Ethics. 38: 277-285. PMID 20579251 DOI: 10.1111/J.1748-720X.2010.00488.X  0.454
2010 Hyun I. The bioethics of stem cell research and therapy Journal of Clinical Investigation. 120: 71-75. PMID 20051638 DOI: 10.1172/Jci40435  0.602
2010 Caulfield T, Scott C, Hyun I, Lovell-Badge R, Kato K, Zarzeczny' A. Stem cell research policy and iPS cells Nature Methods. 7: 28-33. PMID 20038953 DOI: 10.1038/Nmeth.F.282  0.588
2009 Zarzeczny A, Scott C, Hyun I, Bennett J, Chandler J, Chargé S, Heine H, Isasi R, Kato K, Lovell-Badge R, McNagny K, Pei D, Rossant J, Surani A, Taylor PL, et al. iPS cells: mapping the policy issues. Cell. 139: 1032-7. PMID 20005794 DOI: 10.1016/J.Cell.2009.11.039  0.537
2009 Skene L, Testa G, Hyun I, Jung KW, McNab A, Robertson J, Scott CT, Solbakk JH, Taylor P, Zoloth L. Ethics report on interspecies somatic cell nuclear transfer research. Cell Stem Cell. 5: 27-30. PMID 19570511 DOI: 10.1016/J.Stem.2009.06.010  0.538
2009 Lindvall O, Hyun I. Medical innovation versus stem cell tourism. Science (New York, N.Y.). 324: 1664-5. PMID 19556497 DOI: 10.1126/Science.1171749  0.408
2009 Caulfield T, Zarzeczny A, McCormick J, Bubela T, Critchley C, Einsiedel E, Galipeau J, Harmon S, Huynh M, Hyun I, Illes J, Isasi R, Joly Y, Laurie G, Lomax G, et al. The stem cell research environment: a patchwork of patchworks. Stem Cell Reviews. 5: 82-8. PMID 19521798 DOI: 10.1007/S12015-009-9071-3  0.598
2009 Caulfield T, Zarzeczny A, McCormick J, Bubela T, Chritchley C, Einsiedel E, Galipeau J, Harmon S, Huynh M, Hyun I, Illes J, Isasi R, Joly Y, Laurie G, Lomax G, et al. International stem cell environments: a world of difference Stem Cells. 1-1. DOI: 10.1038/Stemcells.2009.61  0.559
2008 Hyun I, Lindvall O, Ahrlund-Richter L, Cattaneo E, Cavazzana-Calvo M, Cossu G, De Luca M, Fox IJ, Gerstle C, Goldstein RA, Hermerén G, High KA, Kim HO, Lee HP, Levy-Lahad E, et al. New ISSCR guidelines underscore major principles for responsible translational stem cell research. Cell Stem Cell. 3: 607-9. PMID 19041777 DOI: 10.1016/J.Stem.2008.11.009  0.557
2008 Hyun I. Stem Cells from Skin Cells: The Ethical Questions Hastings Center Report. 38: 20-22. PMID 18314804 DOI: 10.1353/Hcr.2008.0004  0.615
2008 Robertson JA, Cohen CB, Hyun I. Big bang theory: more reason to scrap Bush's stem cell policy. Hastings Center Report. 38: 4-6. DOI: 10.1353/Hcr.0.0074  0.623
2008 Hyun I. Review of K. R. Monroe, R. B. Miller, and J. Tobis. Fundamentals of the Stem Cell Debate: The Scientific, Religious, Ethical and Political Issues. 1 Review of C. B. Cohen. Renewing the Stuff of Life: Stem Cells, Ethics, and Public Policy. 2 Review of R. Korobkin with S. R. Munzer. Stem Cell Century: Law and Policy for a Breakthrough Technology. 3 American Journal of Bioethics. 8: 57-59. DOI: 10.1080/15265160802248195  0.401
2008 Daley GQ, Hyun I, Lindvall O. Mapping the Road to the Clinical Translation of Stem Cells Cell Stem Cell. 2: 139-140. DOI: 10.1016/J.Stem.2008.01.018  0.474
2007 Hyun I, Taylor P, Testa G, Dickens B, Jung KW, McNab A, Robertson J, Skene L, Zoloth L. Ethical standards for human-to-animal chimera experiments in stem cell research. Cell Stem Cell. 1: 159-63. PMID 18383627 DOI: 10.1016/J.Stem.2007.07.015  0.573
2007 Hyun I, Hochedlinger K, Jaenisch R, Yamanaka S. New advances in iPS cell research do not obviate the need for human embryonic stem cells. Cell Stem Cell. 1: 367-8. PMID 18371375 DOI: 10.1016/J.Stem.2007.09.006  0.411
2007 Caulfield T, Ogbogu U, Nelson E, Einsiedel E, Knoppers B, McDonald M, Brunger F, Downey R, Fernando K, Galipeau J, Geransar R, Grenier G, Hyun I, Isasi R, Kardel M, et al. Stem cell research ethics: consensus statement on emerging issues Journal of Obstetrics and Gynaecology Canada : Jogc = Journal D'ObstéTrique Et GynéCologie Du Canada : Jogc. 29: 843-848. PMID 17915069 DOI: 10.1016/S1701-2163(16)32632-9  0.591
2007 Daley GQ, Ahrlund Richter L, Auerbach JM, Benvenisty N, Charo RA, Chen G, Deng HK, Goldstein LS, Hudson KL, Hyun I, Junn SC, Love J, Lee EH, McLaren A, Mummery CL, et al. Ethics. The ISSCR guidelines for human embryonic stem cell research. Science (New York, N.Y.). 315: 603-4. PMID 17272706 DOI: 10.1126/Science.1139337  0.622
2006 Hyun I, Jung KW. Human Research Cloning, Embryos, and Embryo-Like Artifacts Hastings Center Report. 36: 34-41. PMID 17091700 DOI: 10.1353/Hcr.2006.0080  0.63
2006 Hyun I. Fair payment or undue inducement Nature. 442: 629-630. PMID 16900181 DOI: 10.1038/442629A  0.536
2006 Hyun I. Magic eggs and the frontier of stem cell science. Hastings Center Report. 36: 16-19. PMID 16604893 DOI: 10.1353/Hcr.2006.0025  0.584
2006 Jung KW, Hyun I. Oocyte and somatic cell procurement for stem cell research: The South Korean experience American Journal of Bioethics. 6. PMID 16423766 DOI: 10.1080/15265160500395025  0.557
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