W. V. Graham, Ph.D.
Affiliations: | 2010 | Pathology | University of Chicago, Chicago, IL |
Area:
Molecular Biology, Cell Biology, General BiologyGoogle:
"W. Graham"Parents
Sign in to add mentor| Jerrold R. Turner | grad student | 2010 | Chicago | |
| (Molecular mechanisms of epithelial MLCK isoform regulation: Characterization and pharmacological exploitation.) | ||||
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Publications
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| He WQ, Wang J, Sheng JY, et al. (2020) Contributions of Myosin Light Chain Kinase to Regulation of Epithelial Paracellular Permeability and Mucosal Homeostasis. International Journal of Molecular Sciences. 21 |
| Graham WV, He W, Marchiando AM, et al. (2019) Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis. Nature Medicine |
| He W, Zha J, Wang Y, et al. (2014) Tu1206 Unique Domains Within Long MLCK1 Direct Basal and TNF-Induced Trafficking to the Perijunctional Actomyosin Ring of Intestinal Epithelial Cells Gastroenterology. 146: S-783-S-784 |
| Graham WV, Magis AT, Bailey KM, et al. (2011) Crystallization and preliminary X-ray analysis of the human long myosin light-chain kinase 1-specific domain IgCAM3. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 221-3 |
| Marchiando AM, Shen L, Graham WV, et al. (2011) The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding. Gastroenterology. 140: 1208-1218.e1-2 |
| Marchiando AM, Shen L, Graham WV, et al. (2010) Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo. The Journal of Cell Biology. 189: 111-26 |
| Marchiando AM, Graham WV, Turner JR. (2010) Epithelial barriers in homeostasis and disease. Annual Review of Pathology. 5: 119-44 |
| Graham WV, Marchiando AM, Shen L, et al. (2009) No static at all. Annals of the New York Academy of Sciences. 1165: 314-22 |
| Graham W, Rosenberg HJ, Turner JR. (2009) S1768 Multiple Protein Domains Direct Myosin Light Chain Kinase Isoform 1 (MLCK1) to the Tight Junction in Epithelial Cells Gastroenterology. 136: A-266 |
| Graham WV, Wang Y, Schwarz BT, et al. (2007) Tumor necrosis factor (TNF) increases myosin light chain kinase isoform 1 (MLCK1) transcription and targets MLCK1 to the perijunctional actomyosin ring in vitro and in vivo . The Faseb Journal. 21 |