Cheng Luo, Ph.D. - Publications

Affiliations: 
2000 University of California, Berkeley, Berkeley, CA, United States 
Area:
Applied Mechanics, Mechanical Engineering

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Year Citation  Score
Low-probability matches (unlikely to be authored by this person)
1983 Liu YF, Luo C, Moody KJ, Lee D, Seaborg GT, Von Gunten HR. Procedures for a fast separation of berkelium from complex mixtures of reaction products Journal of Radioanalytical Chemistry. 76: 119-124. DOI: 10.1007/Bf02519662  0.202
1981 Liu Yf, Luo C, von Gunten HR, Seaborg GT. A procedure for a fast separation of berkelium and cerium Inorganic and Nuclear Chemistry Letters. 17: 257-259. DOI: 10.1016/0020-1650(81)80013-X  0.182
1982 Lee D, Von Gunten H, Jacak B, Nurmia M, Liu YF, Luo C, Seaborg GT, Hoffman DC. Production of heavy actinides from interactions of O16, O18, Ne20, and Ne22 with Cm248 Physical Review C. 25: 286-292. DOI: 10.1103/Physrevc.25.286  0.178
2018 Xing J, Zhang R, Jiang X, Hu T, Wang X, Qiao G, Wang J, Yang F, Luo X, Chen K, Shen J, Luo C, Jiang H, Zheng M. Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors. European Journal of Medicinal Chemistry. 163: 281-294. PMID 30529546 DOI: 10.1016/j.ejmech.2018.11.018  0.167
2017 Sun Z, Zhang H, Chen Z, Xie Y, Jiang H, Chen L, Ding H, Zhang Y, Jiang H, Zheng M, Luo C. Discovery of novel BRD4 inhibitors by high-throughput screening, crystallography, and cell-based assays. Bioorganic & Medicinal Chemistry Letters. PMID 28347667 DOI: 10.1016/j.bmcl.2017.03.012  0.165
2017 Mao R, Shao J, Zhu K, Zhang Y, Ding H, Zhang C, Shi Z, Jiang H, Sun DQ, Duan W, Luo C. A Potent, Selective and Cell Active Protein Arginine Methyltransferase 5 (PRMT5) Inhibitor Developed by Structure-based Virtual Screening and Hit Optimization. Journal of Medicinal Chemistry. PMID 28650658 DOI: 10.1021/acs.jmedchem.7b00587  0.162
2016 Wu Y, Hu J, Ding H, Chen L, Zhang Y, Liu R, Xu P, Du D, Lu W, Liu J, Liu Y, Liu YC, Lu J, Zhang J, Yao Z, ... Luo C, et al. Identification of novel EZH2 inhibitors through pharmacophore-based virtual screening and biological assays. Bioorganic & Medicinal Chemistry Letters. PMID 27289323 DOI: 10.1016/j.bmcl.2016.05.018  0.161
2023 Liang X, Cao Y, Duan Z, Wang M, Zhang N, Ding Y, Luo C, Lu N, Chen S. Discovery of new small molecule inhibitors of the BPTF bromodomain. Bioorganic Chemistry. 134: 106453. PMID 36898211 DOI: 10.1016/j.bioorg.2023.106453  0.159
2017 Zhang WY, Lu WC, Jiang H, Lv ZB, Xie YQ, Lian FL, Liang ZJ, Jiang YX, Wang DJ, Luo C, Jin J, Ye F. Discovery of alkyl bis(oxy)dibenzimidamide derivatives as novel protein arginine methyltransferase 1 (PRMT1) inhibitors. Chemical Biology & Drug Design. PMID 28636189 DOI: 10.1111/cbdd.13047  0.158
2019 Zhang D, Han J, Lu W, Lian F, Wang J, Lu T, Tao H, Xiao S, Zhang F, Liu YC, Liu R, Zhang N, Jiang H, Chen K, Zhao C, ... Luo C, et al. Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure-based virtual screening. Bioorganic Chemistry. 86: 494-500. PMID 30780018 DOI: 10.1016/j.bioorg.2019.01.035  0.158
2022 Liu L, Zhu R, Li J, Pei Y, Wang S, Xu P, Wang M, Wen Y, Zhang H, Du D, Ding H, Jiang H, Chen K, Zhou B, Yu L, ... Luo C, et al. Computational and Structure-Based Development of High Potent Cell-Active Covalent Inhibitor Targeting the Peptidyl-Prolyl Isomerase NIMA-Interacting-1 (Pin1). Journal of Medicinal Chemistry. PMID 35089030 DOI: 10.1021/acs.jmedchem.1c01686  0.157
2018 Lu W, Xiong H, Chen Y, Wang C, Zhang H, Xu P, Han J, Xiao S, Ding H, Chen Z, Lu T, Wang J, Zhang Y, Yue L, Liu YC, ... ... Luo C, et al. Discovery and biological evaluation of thiobarbituric derivatives as potent p300/CBP inhibitors. Bioorganic & Medicinal Chemistry. PMID 30297119 DOI: 10.1016/j.bmc.2018.07.048  0.157
2018 Zhu K, Tao H, Song JL, Jin L, Zhang Y, Liu J, Chen Z, Jiang CS, Luo C, Zhang H. Identification of 5-benzylidene-2-phenylthiazolones as potent PRMT5 inhibitors by virtual screening, structural optimization and biological evaluations. Bioorganic Chemistry. 81: 289-298. PMID 30172110 DOI: 10.1016/j.bioorg.2018.08.021  0.156
2017 Chen Z, Zhang H, Liu S, Xie Y, Jiang H, Lu W, Xu H, Yue L, Zhang Y, Ding H, Zheng M, Yu K, Chen K, Jiang H, Luo C. Discovery of novel trimethoxy-ring BRD4 bromodomain inhibitors: AlphaScreen assay, crystallography and cell-based assay. Medchemcomm. 8: 1322-1331. PMID 30108844 DOI: 10.1039/c7md00083a  0.155
2018 Chen W, Zhang H, Chen Z, Jiang H, Liao L, Fan S, Xing J, Xie Y, Chen S, Ding H, Chen K, Jiang H, Luo C, Zheng M, Yao Z, et al. Development and evaluation of a novel series of Nitroxoline-derived BET inhibitors with antitumor activity in renal cell carcinoma. Oncogenesis. 7: 83. PMID 30385738 DOI: 10.1038/s41389-018-0093-z  0.154
2021 Li W, Liao LP, Song N, Liu YJ, Ding YL, Zhang YY, Zhou XR, Sun ZY, Xiao SH, Wang HB, Lu J, Zhang NX, Jiang HL, Chen KX, Liu CP, ... ... Luo C, et al. Natural product 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase. Acta Pharmacologica Sinica. PMID 33850276 DOI: 10.1038/s41401-021-00653-0  0.154
2016 Ye F, Zhang W, Lu W, Xie Y, Jiang H, Jin J, Luo C. Identification of Novel Inhibitors against Coactivator Associated Arginine Methyltransferase 1 Based on Virtual Screening and Biological Assays. Biomed Research International. 2016: 7086390. PMID 27872854 DOI: 10.1155/2016/7086390  0.154
2018 Zhu K, Jiang C, Tao H, Liu J, Zhang H, Luo C. Identification of a novel selective small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5) by virtual screening, resynthesis and biological evaluations. Bioorganic & Medicinal Chemistry Letters. PMID 29628326 DOI: 10.1016/j.bmcl.2018.03.087  0.153
2019 Zhang FC, Sun ZY, Liao LP, Zuo Y, Zhang D, Wang J, Chen YT, Xiao SH, Jiang H, Lu T, Xu P, Yue LY, Du DH, Zhang H, Liu CP, ... Luo C, et al. Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening. Acta Pharmacologica Sinica. PMID 31253937 DOI: 10.1038/s41401-019-0256-2  0.153
2006 Chen L, Li J, Luo C, Liu H, Xu W, Chen G, Liew OW, Zhu W, Puah CM, Shen X, Jiang H. Binding interaction of quercetin-3-beta-galactoside and its synthetic derivatives with SARS-CoV 3CL(pro): structure-activity relationship studies reveal salient pharmacophore features. Bioorganic & Medicinal Chemistry. 14: 8295-306. PMID 17046271 DOI: 10.1016/j.bmc.2006.09.014  0.153
2014 Xie Y, Zhou R, Lian F, Liu Y, Chen L, Shi Z, Zhang N, Zheng M, Shen B, Jiang H, Liang Z, Luo C. Virtual screening and biological evaluation of novel small molecular inhibitors against protein arginine methyltransferase 1 (PRMT1). Organic & Biomolecular Chemistry. 12: 9665-73. PMID 25348815 DOI: 10.1039/c4ob01591f  0.153
2017 Wang Y, Li L, Zhang B, Xing J, Chen S, Wan W, Song Y, Jiang H, Jiang H, Luo C, Zheng M. Discovery of Novel Disruptor of Silencing Telomeric 1-Like (DOT1L) Inhibitors using a Target-specific Scoring Function for the S-adenosyl-L-methionine (SAM)-dependent Methyltransferase Family. Journal of Medicinal Chemistry. PMID 28165739 DOI: 10.1021/acs.jmedchem.6b01785  0.152
2018 Song Y, Li L, Chen Y, Liu J, Xiao S, Lian F, Zhang N, Ding H, Zhang Y, Chen K, Jiang H, Zhang C, Liu YC, Chen S, Luo C. Discovery of potent DOT1L inhibitors by AlphaLISA based High Throughput Screening assay. Bioorganic & Medicinal Chemistry. PMID 29534934 DOI: 10.1016/j.bmc.2018.02.020  0.152
2021 Du D, Xu D, Zhu L, Stazi G, Zwergel C, Liu Y, Luo Z, Li Y, Zhang Y, Zhu K, Ding Y, Liu J, Fan S, Zhao K, Zhang N, ... ... Luo C, et al. Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction. Journal of Medicinal Chemistry. PMID 34077206 DOI: 10.1021/acs.jmedchem.0c02261  0.151
2023 Xu H, Zhao H, Ding C, Jiang D, Zhao Z, Li Y, Ding X, Gao J, Zhou H, Luo C, Chen G, Zhang A, Xu Y, Zhang H. Celastrol suppresses colorectal cancer via covalent targeting peroxiredoxin 1. Signal Transduction and Targeted Therapy. 8: 51. PMID 36732502 DOI: 10.1038/s41392-022-01231-4  0.151
2019 Lu W, Wang J, Li Y, Tao H, Xiong H, Lian F, Gao J, Ma H, Lu T, Zhang D, Ye X, Ding H, Yue L, Zhang Y, Tang H, ... ... Luo C, et al. Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors. European Journal of Medicinal Chemistry. 184: 111767. PMID 31622854 DOI: 10.1016/j.ejmech.2019.111767  0.15
2022 Wu Q, Sun Z, Chen Z, Liu J, Ding H, Luo C, Wang M, Du D. The discovery of a non-competitive GOT1 inhibitor, hydralazine hydrochloride, via a coupling reaction-based high-throughput screening assay. Bioorganic & Medicinal Chemistry Letters. 73: 128883. PMID 35820623 DOI: 10.1016/j.bmcl.2022.128883  0.15
2021 Li XJ, Zhang YY, Fu YH, Zhang H, Li HX, Li QF, Li HL, Tan RK, Jiang CX, Jiang W, Li ZX, Luo C, Lu BX, Dang YJ. Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex. Acta Pharmacologica Sinica. PMID 33495516 DOI: 10.1038/s41401-020-00605-0  0.15
2021 Gao F, Chen X, Lu J, Hu S, Xu H, Shi Y, Feng M, Ding J, Liu H, Luo C, Xie Z, Wang J. Discovery of novel ceramide analogs with favorable pharmacokinetic properties and combination with AKT inhibitor against colon cancer. European Journal of Medicinal Chemistry. 215: 113274. PMID 33592537 DOI: 10.1016/j.ejmech.2021.113274  0.15
2019 Zhu K, Shao J, Tao H, Yan X, Luo C, Zhang H, Duan W. Rational Design, synthesis and biological evaluation of novel triazole derivatives as potent and selective PRMT5 inhibitors with antitumor activity. Journal of Computer-Aided Molecular Design. PMID 31312965 DOI: 10.1007/s10822-019-00214-y  0.149
2017 Li J, Gao Z, Zhao D, Zhang L, Qiao X, Zhao Y, Ding H, Zhang P, Lu J, Liu J, Jiang H, Luo C, Chen C. PI-273, a substrate-competitive, specific small molecule inhibitor of PI4KIIα, inhibits the growth of breast cancer cells. Cancer Research. PMID 28827373 DOI: 10.1158/0008-5472.CAN-17-0484  0.149
2019 Lu T, Lu W, Luo C. A patent review of BRD4 inhibitors (2013-2019). Expert Opinion On Therapeutic Patents. PMID 31815566 DOI: 10.1080/13543776.2020.1702645  0.148
2022 Li X, Zhang L, Xu J, Liu C, Zhang X, Abdelmoneim AA, Zhang Q, Ke J, Zhang Y, Wang L, Yang F, Luo C, Jin J, Ye F. Identification, Synthesis, and Biological Evaluations of Potent Inhibitors Targeting Type I Protein Arginine Methyltransferases. Journal of Chemical Information and Modeling. PMID 35098713 DOI: 10.1021/acs.jcim.1c01100  0.148
2013 Li Y, Frenz CM, Li Z, Chen M, Wang Y, Li F, Luo C, Sun J, bohlin L, Li Z, Yang H, Wang C. Virtual and in vitro bioassay screening of phytochemical inhibitors from flavonoids and isoflavones against xanthine oxidase and cyclooxygenase-2 for gout treatment. Chemical Biology & Drug Design. 81: 537-44. PMID 23534413 DOI: 10.1111/cbdd.1248  0.148
2017 McClary B, Zinshteyn B, Meyer M, Jouanneau M, Pellegrino S, Yusupova G, Schuller A, Reyes JCP, Lu J, Guo Z, Ayinde S, Luo C, Dang Y, Romo D, Yusupov M, et al. Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A. Cell Chemical Biology. PMID 28457705 DOI: 10.1016/J.Chembiol.2017.04.006  0.148
2020 Zhang B, Liao L, Wu F, Zhang F, Sun Z, Chen H, Luo C. Synthesis and structure-activity relationship studies of LLY-507 analogues as SMYD2 inhibitors. Bioorganic & Medicinal Chemistry Letters. 127598. PMID 33011288 DOI: 10.1016/j.bmcl.2020.127598  0.147
2019 Tao H, Wang J, Lu W, Zhang R, Xie Y, Liu YC, Liu R, Yue L, Chen K, Jiang H, Zhang Y, Xu X, Luo C. Discovery of trisubstituted nicotinonitrile derivatives as novel human GCN5 inhibitors through AlphaScreen-based high throughput screening. Rsc Advances. 9: 4917-4924. PMID 35514635 DOI: 10.1039/c8ra10074h  0.147
2017 Ye Y, Zhang B, Mao R, Zhang C, Wang Y, Xing J, Liu YC, Luo X, Ding H, Yang Y, Zhou B, Jiang H, Chen K, Luo C, Zheng M. Discovery and optimization of selective inhibitors of protein arginine methyltransferase 5 by docking-based virtual screening. Organic & Biomolecular Chemistry. PMID 28397890 DOI: 10.1039/c7ob00070g  0.147
2020 Chen Y, Bi X, Zhang F, Sun Z, Xu P, Jiang H, Lu W, Lu T, Ding H, Zhang N, Jiang H, Chen K, Zhou B, Luo C. Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain. Bioorganic Chemistry. 101: 103991. PMID 32559581 DOI: 10.1016/j.bioorg.2020.103991  0.147
2018 Liu J, Chen Y, Li JY, Luo C, Li J, Chen KX, Li XW, Guo YW. Function-Oriented Synthesis of Marine Phidianidine Derivatives as Potential PTP1B Inhibitors with Specific Selectivity. Marine Drugs. 16. PMID 29558377 DOI: 10.3390/md16030097  0.147
2016 Shao Z, Xu P, Xu W, Li L, Liu S, Zhang R, Liu YC, Zhang C, Chen S, Luo C. Discovery of novel DNA methyltransferase 3A inhibitors via structure-based virtual screening and biological assays. Bioorganic & Medicinal Chemistry Letters. PMID 27899265 DOI: 10.1016/j.bmcl.2016.11.023  0.147
2018 Ye X, Zhang R, Lian F, Zhang W, Lu W, Han J, Zhang N, Jin J, Luo C, Chen K, Ye F, Ding H. The identification of novel small-molecule inhibitors targeting WDR5-MLL1 interaction through fluorescence polarization based high-throughput screening. Bioorganic & Medicinal Chemistry Letters. PMID 30626558 DOI: 10.1016/j.bmcl.2018.12.035  0.146
2021 Wang J, Wang C, Xu P, Li X, Lu Y, Jin D, Yin X, Jiang H, Huang J, Xiong H, Ye F, Jin J, Chen Y, Xie Y, Chen Z, ... ... Luo C, et al. PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma. Theranostics. 11: 5387-5403. PMID 33859753 DOI: 10.7150/thno.42345  0.146
2012 Wang J, Chen L, Sinha SH, Liang Z, Chai H, Muniyan S, Chou YW, Yang C, Yan L, Feng Y, Li KK, Lin MF, Jiang H, Zheng YG, Luo C. Pharmacophore-based virtual screening and biological evaluation of small molecule inhibitors for protein arginine methylation. Journal of Medicinal Chemistry. 55: 7978-87. PMID 22928876 DOI: 10.1021/jm300521m  0.146
2018 Xiong H, Han J, Wang J, Lu W, Wang C, Chen Y, Fulin Lian, Zhang N, Liu YC, Zhang C, Ding H, Jiang H, Lu W, Luo C, Zhou B. Discovery of 1,8-acridinedione derivatives as novel GCN5 inhibitors via high throughput screening. European Journal of Medicinal Chemistry. 151: 740-751. PMID 29665527 DOI: 10.1016/j.ejmech.2018.02.005  0.146
2018 Ye F, Zhang W, Ye X, Jin J, Lv Z, Luo C. Identification of Selective, Cell Active Inhibitors of Protein Arginine Methyltransferase 5 (PRMT5) through Structure-Based Virtual Screening and Biological Assays. Journal of Chemical Information and Modeling. PMID 29672052 DOI: 10.1021/acs.jcim.8b00050  0.145
2017 Jiang H, Xing J, Wang C, Zhang H, Yue L, Wan X, Chen W, Ding H, Xie Y, Tao H, Chen Z, Jiang H, Chen K, Chen S, Zheng M, ... ... Luo C, et al. Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues. Organic & Biomolecular Chemistry. PMID 29087414 DOI: 10.1039/c7ob02369c  0.145
2019 Li X, Wang C, Jiang H, Luo C. A patent review of arginine methyltransferase inhibitors (2010-2018). Expert Opinion On Therapeutic Patents. PMID 30640571 DOI: 10.1080/13543776.2019.1567711  0.144
2018 Lu T, Hu JC, Lu WC, Han J, Ding H, Jiang H, Zhang YY, Yue LY, Chen SJ, Jiang HL, Chen KX, Chai HF, Luo C. Identification of small molecule inhibitors targeting the SMARCA2 bromodomain from a high-throughput screening assay. Acta Pharmacologica Sinica. PMID 29795359 DOI: 10.1038/aps.2017.188  0.144
2023 Liu Z, Jiang S, Hao B, Xie S, Liu Y, Huang Y, Xu H, Luo C, Huang M, Tan M, Xu JY. A proteomic landscape of pharmacologic perturbations for functional relevance. Journal of Pharmaceutical Analysis. 14: 128-139. PMID 38352953 DOI: 10.1016/j.jpha.2023.08.021  0.144
2019 Xu X, Kuang Z, Han J, Meng Y, Li L, Luan H, Xu P, Wang J, Luo C, Ding H, Li Z, Bian J. Development and Characterization of a Fluorescent Probe for GLS1 and the Application for High-Throughput Screening of Allosteric Inhibitors. Journal of Medicinal Chemistry. PMID 31603674 DOI: 10.1021/acs.jmedchem.9b01035  0.144
2017 Wang C, Jiang H, Jin J, Xie Y, Chen Z, Zhang H, Lian F, Liu YC, Zhang C, Ding H, Chen S, Zhang N, Zhang Y, Jiang H, Chen K, ... ... Luo C, et al. Development of Potent Type I Protein Arginine Methyltransferase (PRMT) Inhibitors Inhibiting Leukemia Cells Proliferation. Journal of Medicinal Chemistry. PMID 29019697 DOI: 10.1021/acs.jmedchem.7b01134  0.144
2021 Lin T, Li J, Liu L, Li Y, Jiang H, Chen K, Xu P, Luo C, Zhou B. Design, synthesis, and biological evaluation of 4-benzoylamino-1H-pyrazole-3-carboxamide derivatives as potent CDK2 inhibitors. European Journal of Medicinal Chemistry. 215: 113281. PMID 33611192 DOI: 10.1016/j.ejmech.2021.113281  0.144
2020 Sun Z, Zhang H, Zhang Y, Liao L, Zhou W, Zhang F, Lian F, Huang J, Xu P, Zhang R, Lu W, Zhu M, Tao H, Yang F, Ding H, ... ... Luo C, et al. Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 7: 2000098. PMID 32714746 DOI: 10.1002/Advs.202000098  0.143
2017 Zhu K, Jiang CS, Hu J, Liu X, Yan X, Tao H, Luo C, Zhang H. Interaction assessments of the first S-adenosylmethionine competitive inhibitor and the essential interacting partner methylosome protein 50 with protein arginine methyltransferase 5 by combined computational methods. Biochemical and Biophysical Research Communications. PMID 29154828 DOI: 10.1016/j.bbrc.2017.11.089  0.143
2017 Zhou P, Liang Y, Zhang H, Jiang H, Feng K, Xu P, Wang J, Wang X, Ding K, Luo C, Liu M, Wang Y. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents. European Journal of Medicinal Chemistry. 144: 817-842. PMID 29306206 DOI: 10.1016/J.Ejmech.2017.12.004  0.14
2020 Bi X, Chen Y, Sun Z, Lu W, Xu P, Lu T, Ding H, Zhang N, Jiang H, Chen K, Zhou B, Luo C. Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors. Bioorganic & Medicinal Chemistry Letters. 127480. PMID 32882416 DOI: 10.1016/j.bmcl.2020.127480  0.14
2015 Zhou R, Xie Y, Hu H, Hu G, Patel VS, Zhang J, Yu K, Huang Y, Jiang H, Liang Z, Zheng YG, Luo C. Molecular Mechanism underlying PRMT1 Dimerization for SAM Binding and Methylase Activity. Journal of Chemical Information and Modeling. PMID 26562720 DOI: 10.1021/acs.jcim.5b00454  0.14
2015 Lu J, Zeng H, Liang Z, Chen L, Zhang L, Zhang H, Liu H, Jiang H, Shen B, Huang M, Geng M, Spiegel S, Luo C. Network modelling reveals the mechanism underlying colitis-associated colon cancer and identifies novel combinatorial anti-cancer targets. Scientific Reports. 5: 14739. PMID 26446703 DOI: 10.1038/srep14739  0.139
2016 Guo ZQ, Zheng T, Chen B, Luo C, Ouyang S, Gong S, Li J, Mao LL, Lian F, Yang Y, Huang Y, Li L, Lu J, Zhang B, Zhou L, et al. Small-Molecule Targeting of E3 Ligase Adaptor SPOP in Kidney Cancer. Cancer Cell. 30: 474-484. PMID 27622336 DOI: 10.1016/j.ccell.2016.08.003  0.139
2019 Jiang C, Tang Y, Ding L, Tan R, Li X, Lu J, Jiang J, Cui Z, Tang Z, Li W, Cao Z, Schneider-Poetsch T, Jiang W, Luo C, Ding Y, et al. Targeting the N Terminus of eIF4AI for Inhibition of Its Catalytic Recycling. Cell Chemical Biology. PMID 31402318 DOI: 10.1016/J.Chembiol.2019.07.010  0.139
2021 Zhou XR, Li X, Liao LP, Han J, Huang J, Li JC, Tao HR, Fan SJ, Chen ZF, Li Q, Chen SJ, Ding H, Yang YX, Zhou B, Jiang HL, ... ... Luo C, et al. P300/CBP inhibition sensitizes mantle cell lymphoma to PI3Kδ inhibitor idelalisib. Acta Pharmacologica Sinica. PMID 33850273 DOI: 10.1038/s41401-021-00643-2  0.138
2014 Chen S, Wang Y, Zhou W, Li S, Peng J, Shi Z, Hu J, Liu YC, Ding H, Lin Y, Li L, Cheng S, Liu J, Lu T, Jiang H, ... ... Luo C, et al. Identifying novel selective non-nucleoside DNA methyltransferase 1 inhibitors through docking-based virtual screening. Journal of Medicinal Chemistry. 57: 9028-41. PMID 25333769 DOI: 10.1021/jm501134e  0.138
2016 Chen S, Li L, Chen Y, Hu J, Liu J, Liu YC, Liu R, Zhang Y, Meng F, Zhu K, Lu J, Zheng M, Chen K, Zhang J, Jiang H, ... ... Luo C, et al. Identification of Novel Disruptor of Telomeric Silencing 1-Like (DOT1L) Inhibitors through Structure-Based Virtual Screening and Biological Assays. Journal of Chemical Information and Modeling. PMID 26914852 DOI: 10.1021/acs.jcim.5b00738  0.138
2021 Sun Y, Lu H, Fang X, Xiao S, Yang F, Chen Y, Wang H, Li X, Lu J, Lin H, Luo C, Zhao K, Chen S. Discovery of a novel 53BP1 inhibitor through AlphaScreen-based high-throughput screening. Bioorganic & Medicinal Chemistry. 34: 116054. PMID 33571875 DOI: 10.1016/j.bmc.2021.116054  0.138
2018 Zhang L, Chen Y, Liu N, Li L, Xiao S, Li X, Chen K, Luo C, Chen S, Chen H. Design, synthesis and anti leukemia cells proliferation activities of pyrimidylaminoquinoline derivatives as DOT1L inhibitors. Bioorganic Chemistry. 80: 649-654. PMID 30059890 DOI: 10.1016/j.bioorg.2018.07.022  0.138
2020 Dong Z, Wang Z, Guo ZQ, Gong S, Zhang T, Liu J, Luo C, Jiang H, Yang CG. Structure-activity Relationship of SPOP Inhibitors Against Kidney Cancer. Journal of Medicinal Chemistry. PMID 32297747 DOI: 10.1021/acs.jmedchem.0c00161  0.137
2021 Luo Z, Du D, Liu Y, Lu T, Liu L, Jiang H, Chen K, Shan C, Luo C. Discovery and characterization of a novel glucose-6-phosphate dehydrogenase (G6PD) inhibitor via high-throughput screening. Bioorganic & Medicinal Chemistry Letters. 127905. PMID 33689874 DOI: 10.1016/j.bmcl.2021.127905  0.137
2018 Shao J, Zhu K, Du D, Zhang Y, Tao H, Chen Z, Jiang H, Chen K, Luo C, Duan W. Discovery of 2-substituted-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide as potent and selective protein arginine methyltransferases 5 inhibitors: Design, synthesis and biological evaluation. European Journal of Medicinal Chemistry. 164: 317-333. PMID 30605830 DOI: 10.1016/j.ejmech.2018.12.065  0.136
2023 Wu X, Wang M, Cao Y, Xu Y, Yang Z, Ding Y, Lu J, Zheng J, Luo C, Zhao K, Chen S. Discovery of a novel OGT inhibitor through high-throughput screening based on Homogeneous Time-Resolved Fluorescence (HTRF). Bioorganic Chemistry. 139: 106726. PMID 37451145 DOI: 10.1016/j.bioorg.2023.106726  0.136
2024 Liu Z, Lin M, Liu C, Chen X, Chen Q, Li X, Wu X, Wang Y, Wang L, Yang F, Luo C, Jin J, Ye F. Development of (2-(Benzyloxy)phenyl)methanamine Derivatives as Potent and Selective Inhibitors of CARM1 for the Treatment of Melanoma. Journal of Medicinal Chemistry. PMID 38574345 DOI: 10.1021/acs.jmedchem.3c02265  0.136
2015 Shi L, Pi Y, Luo C, Zhang C, Tan D, Meng X. In vitro inhibitory activities of six gypenosides on human liver cancer cell line HepG2 and possible role of HIF-1α pathway in them. Chemico-Biological Interactions. 238: 48-54. PMID 26054451 DOI: 10.1016/j.cbi.2015.06.004  0.136
2023 Xie Y, Fan S, Ni D, Wan W, Xu P, Ding Y, Zhang R, Lu J, Zhang N, Zhang Y, Xiao W, Zhao K, Luo C. An ATG4B inhibitor blocks autophagy and sensitizes Sorafenib inhibition activities in HCC tumor cells. Bioorganic & Medicinal Chemistry. 84: 117262. PMID 37018878 DOI: 10.1016/j.bmc.2023.117262  0.135
2019 Jiang J, Zhang H, Wang C, Zhang Q, Fang S, Zhou R, Hu J, Zhu J, Zhou Y, Luo C, Zheng C. 1-Phenyl-dihydrobenzoindazoles as novel colchicine site inhibitors: Structural basis and antitumor efficacy. European Journal of Medicinal Chemistry. 177: 448-456. PMID 31174062 DOI: 10.1016/j.ejmech.2019.04.040  0.135
2020 Jiang S, Luo C, Huang Y, Li Z, Chen Y, Li X, Pei H, Wang P, Wang X, Yao D. Altered Static and Dynamic Spontaneous Neural Activity in Drug-Naïve and Drug-Receiving Benign Childhood Epilepsy With Centrotemporal Spikes. Frontiers in Human Neuroscience. 14: 361. PMID 33005141 DOI: 10.3389/fnhum.2020.00361  0.135
2022 Li E, Wang K, Zhang B, Guo S, Xiao S, Pan Q, Wang X, Chen W, Wu Y, Xu H, Kong X, Luo C, Chen S, Liu B. Design, synthesis, and biological evaluation of novel carbazole derivatives as potent DNMT1 inhibitors with reasonable PK properties. Journal of Enzyme Inhibition and Medicinal Chemistry. 37: 1537-1555. PMID 35670075 DOI: 10.1080/14756366.2022.2079640  0.135
2018 Feng Y, Xiao S, Chen Y, Jiang H, Liu N, Luo C, Chen S, Chen H. Design, synthesis and biological evaluation of benzo[cd]indol-2(1H)-ones derivatives as BRD4 inhibitors. European Journal of Medicinal Chemistry. 152: 264-273. PMID 29730189 DOI: 10.1016/j.ejmech.2018.04.048  0.135
2011 Liang Z, Zhang L, Li L, Liu J, Li H, Zhang L, Chen L, Cheng K, Zheng M, Wen X, Zhang P, Hao J, Gong Y, Zhang X, Zhu X, ... ... Luo C, et al. Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies. European Journal of Medicinal Chemistry. 46: 2011-21. PMID 21439694 DOI: 10.1016/j.ejmech.2011.02.053  0.134
2023 Li P, Tian Y, Shang Q, Tang C, Hou Z, Li Y, Cao L, Xue S, Bian J, Luo C, Wu D, Li Z, Ding H. Discovery of a highly potent NPAS3 heterodimer inhibitor by covalently modifying ARNT. Bioorganic Chemistry. 139: 106676. PMID 37352720 DOI: 10.1016/j.bioorg.2023.106676  0.134
2023 Guo S, Jia T, Xu X, Yang F, Xiao S, Hou Z, Xu H, Ma S, Liu X, Luo C, Jiang H, Chen H, Chen S. Design, synthesis of novel benzimidazole derivatives as ENL inhibitors suppressing leukemia cells viability via downregulating the expression of MYC. European Journal of Medicinal Chemistry. 248: 115093. PMID 36645983 DOI: 10.1016/j.ejmech.2023.115093  0.134
2020 Han J, Tian Y, Yu L, Zhang Q, Xu X, Zhang Y, Wang J, Ma Z, Bian J, Luo C, Jiang H, Chen K, Zhao Y, Li Z, Ding H. Discovery of novel USP8 inhibitors via Ubiquitin-Rho-110 fluorometric assay based high throughput screening. Bioorganic Chemistry. 101: 103962. PMID 32480171 DOI: 10.1016/j.bioorg.2020.103962  0.134
2019 Chen D, Lu T, Yan Z, Lu W, Zhou F, Lyu X, Xu B, Jiang H, Chen K, Luo C, Zhao Y. Discovery, structural insight, and bioactivities of BY27 as a selective inhibitor of the second bromodomains of BET proteins. European Journal of Medicinal Chemistry. 182: 111633. PMID 31461688 DOI: 10.1016/j.ejmech.2019.111633  0.134
2016 Xu Y, Yue L, Wang Y, Xing J, Chen Z, Shi Z, Liu R, Liu YC, Luo X, Jiang H, Chen K, Luo C, Zheng M. Discovery of Novel Inhibitors Targeting Menin-Mixed Lineage Leukemia (MLL) Interface Using Pharmacophore- and Docking-Based Virtual Screening. Journal of Chemical Information and Modeling. PMID 27513308 DOI: 10.1021/acs.jcim.6b00185  0.134
2014 Kong X, Chen L, Jiao L, Jiang X, Lian F, Lu J, Zhu K, Du D, Liu J, Ding H, Zhang N, Shen J, Zheng M, Chen K, Liu X, ... ... Luo C, et al. Astemizole arrests the proliferation of cancer cells by disrupting the EZH2-EED interaction of polycomb repressive complex 2. Journal of Medicinal Chemistry. 57: 9512-21. PMID 25369470 DOI: 10.1021/Jm501230C  0.133
2022 Liu T, Shi W, Ding Y, Wu Q, Zhang B, Zhang N, Wang M, Du D, Zhang H, Han B, Guo D, Zheng J, Li Q, Luo C. (-)-Epigallocatechin Gallate is a Noncompetitive Inhibitor of NAD Kinase. Acs Medicinal Chemistry Letters. 13: 1699-1706. PMID 36385933 DOI: 10.1021/acsmedchemlett.2c00163  0.133
2024 Lai Q, Wan Y, Zhang Y, Huang Y, Tang Q, Chen M, Li Q, Ma K, Xiao P, Luo C, Zhuang X. Hypomethylation-associated LINC00987 downregulation induced lung adenocarcinoma progression by inhibiting the phosphorylation-mediated degradation of SND1. Molecular Carcinogenesis. PMID 38607240 DOI: 10.1002/mc.23722  0.133
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2013 Xu Y, Liu X, Li S, Zhou N, Gong L, Luo C, Luo X, Zheng M, Jiang H, Chen K. Combinatorial pharmacophore modeling of organic cation transporter 2 (OCT2) inhibitors: insights into multiple inhibitory mechanisms. Molecular Pharmaceutics. 10: 4611-9. PMID 24152391 DOI: 10.1021/mp400423g  0.132
2018 Ding H, Lu WC, Hu JC, Liu YC, Zhang CH, Lian FL, Zhang NX, Meng FW, Luo C, Chen KX. Identification and Characterizations of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Scaffold Hopping- and 2D-Molecular Fingerprint-Based Similarity Search. Molecules (Basel, Switzerland). 23. PMID 29498708 DOI: 10.3390/molecules23030567  0.131
2014 Li L, Zhou R, Geng H, Yue L, Ye F, Xie Y, Liu J, Kong X, Jiang H, Huang J, Luo C. Discovery of two aminoglycoside antibiotics as inhibitors targeting the menin-mixed lineage leukaemia interface. Bioorganic & Medicinal Chemistry Letters. 24: 2090-3. PMID 24709560 DOI: 10.1016/j.bmcl.2014.03.055  0.131
2023 Bai Y, Liu Z, Li Y, Zhao H, Lai C, Zhao S, Chen K, Luo C, Yang X, Wang F. Structural Mass Spectrometry Probes the Inhibitor-Induced Allosteric Activation of CDK12/CDK13-Cyclin K Dissociation. Journal of the American Chemical Society. PMID 37207290 DOI: 10.1021/jacs.3c01697  0.13
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2004 Luo C, Laaja P. Inhibitors of JAKs/STATs and the kinases: a possible new cluster of drugs. Drug Discovery Today. 9: 268-75. PMID 15003245 DOI: 10.1016/S1359-6446(03)03014-9  0.13
2004 Chen G, Luo X, Zhu W, Luo C, Liu H, Puah CM, Chen K, Jiang H. Elucidating inhibitory models of the inhibitors of epidermal growth factor receptor by docking and 3D-QSAR. Bioorganic & Medicinal Chemistry. 12: 2409-17. PMID 15080937 DOI: 10.1016/j.bmc.2004.02.001  0.13
2020 Li Z, Xiao S, Yang Y, Chen C, Lu T, Chen Z, Jiang H, Chen S, Luo C, Zhou B. Discovery of 8-Methyl-pyrrolo[1,2-a]pyrazin-1(2H)-one Derivatives as Highly Potent and Selective Bromodomain and Extra-terminal (BET) Bromodomain Inhibitors. Journal of Medicinal Chemistry. PMID 32208600 DOI: 10.1021/acs.jmedchem.9b01784  0.129
2021 Ding H, Pei Y, Li Y, Xu W, Mei L, Hou Z, Guang Y, Cao L, Li P, Cao H, Bian J, Chen K, Luo C, Zhou B, Zhang T, et al. Design, synthesis and biological evaluation of a novel spiro oxazolidinedione as potent p300/CBP HAT inhibitor for the treatment of ovarian cancer. Bioorganic & Medicinal Chemistry. 52: 116512. PMID 34801827 DOI: 10.1016/j.bmc.2021.116512  0.129
2020 Zhou Y, Du DH, Wang J, Cai XQ, Deng AX, Nosjean O, Boutin JA, Renard P, Yang DH, Luo C, Wang MW. Identification of catalytic and non-catalytic activity inhibitors against PRC2-EZH2 complex through multiple high-throughput screening campaigns. Chemical Biology & Drug Design. PMID 32394628 DOI: 10.1111/cbdd.13702  0.129
2016 Yue L, Du J, Ye F, Chen Z, Li L, Lian F, Zhang B, Zhang Y, Jiang H, Chen K, Li Y, Zhou B, Zhang N, Yang Y, Luo C. Identification of novel small-molecule inhibitors targeting menin-MLL interaction, repurposing the antidiarrheal loperamide. Organic & Biomolecular Chemistry. PMID 27541268 DOI: 10.1039/c6ob01248e  0.128
2019 Yang F, Zhang R, Ni D, Luo X, Chen S, Luo C, Xiao W. Discovery of betulinaldehyde as a natural RORγt agonist. Fitoterapia. 104200. PMID 31195082 DOI: 10.1016/j.fitote.2019.104200  0.128
2019 Duan Z, Liu J, Niu L, Wang J, Feng M, Chen H, Luo C. Discovery of DC_H31 as potential mutant IDH1 inhibitor through NADPH-based high throughput screening. Bioorganic & Medicinal Chemistry. PMID 31208797 DOI: 10.1016/j.bmc.2019.05.040  0.128
2019 Ye F, Huang J, Wang H, Luo C, Zhao K. Targeting epigenetic machinery: Emerging novel allosteric inhibitors. Pharmacology & Therapeutics. 107406. PMID 31521697 DOI: 10.1016/j.pharmthera.2019.107406  0.128
2020 Zuo Y, Xu H, Chen Z, Xiong F, Zhang B, Chen K, Jiang H, Luo C, Zhang H. 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells. Oncology Reports. PMID 32236631 DOI: 10.3892/or.2020.7563  0.128
2015 Luo C, Zhang Y, Cao W, Huang Y, Yang F, Wang J, Tu S, Wang X, Yao D. Altered Structural and Functional Feature of Striato-Cortical Circuit In Benign Epilepsy with Centrotemporal Spikes. International Journal of Neural Systems. 1550027. PMID 26126612 DOI: 10.1142/S0129065715500276  0.127
2020 Hou Z, Min W, Zhang R, Niu A, Li Y, Cao L, Han J, Luo C, Yang P, Ding H. Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors. Bioorganic & Medicinal Chemistry Letters. 127061. PMID 32173197 DOI: 10.1016/j.bmcl.2020.127061  0.127
2015 Wang J, Luo C, Shan C, You Q, Lu J, Elf S, Zhou Y, Wen Y, Vinkenborg JL, Fan J, Kang H, Lin R, Han D, Xie Y, Karpus J, et al. Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation. Nature Chemistry. 7: 968-979. PMID 26587712 DOI: 10.1038/Nchem.2381  0.127
2021 Ding X, Zhao Z, Wu Y, Zhang H, Chen K, Luo C, Luo X, Xu H. Identification of novel anti-inflammatory Nur77 modulators by virtual screening. Bioorganic Chemistry. 112: 104912. PMID 33933804 DOI: 10.1016/j.bioorg.2021.104912  0.127
2023 Ni Y, Luo Z, Lv Y, Ma S, Luo C, Du D. Thimerosal, a competitive thioredoxin reductase 1 (TrxR1) inhibitor discovered via high-throughput screening. Biochemical and Biophysical Research Communications. 650: 117-122. PMID 36780763 DOI: 10.1016/j.bbrc.2023.02.014  0.126
2023 Hu L, Li H, Qin J, Yang D, Liu J, Luo X, Ma J, Luo C, Ye F, Zhou Y, Li J, Wang M. Discovery of PVD-06 as a Subtype-Selective and Efficient PTPN2 Degrader. Journal of Medicinal Chemistry. PMID 37966047 DOI: 10.1021/acs.jmedchem.3c01348  0.126
2014 Luo C, Yang T, Tu S, Deng J, Liu D, Li Q, Dong L, Goldberg I, Gong Q, Zhang D, An D, Zhou D, Yao D. Altered intrinsic functional connectivity of the salience network in childhood absence epilepsy. Journal of the Neurological Sciences. 339: 189-95. PMID 24642509 DOI: 10.1016/j.jns.2014.02.016  0.126
2023 Gao J, Yang J, Xue S, Ding H, Lin H, Luo C. A patent review of PRMT5 inhibitors to treat cancer (2018 - present). Expert Opinion On Therapeutic Patents. PMID 37072380 DOI: 10.1080/13543776.2023.2201436  0.126
2016 Ni T, Ye F, Liu X, Zhang J, Liu HL, Li J, Yingyi Z, Sun Y, Wang M, Luo C, Jiang H, Lan L, Gan J, Zhang A, Zhou H, et al. Characterization of Gain-of-function Mutant Provides New Insights into ClpP Structure. Acs Chemical Biology. PMID 27171654 DOI: 10.1021/Acschembio.6B00390  0.126
2024 Wu XY, Zhao ZY, Osman EEA, Wang XJ, Choo YM, Benjamin MM, Xiong J, Hamann MT, Luo C, Hu JF. Platanosides from Platanus × acerifolia: New molecules, SAR, and target validation of a strong lead for drug-resistant bacterial infections and the associated sepsis. Bioorganic Chemistry. 143: 107103. PMID 38211549 DOI: 10.1016/j.bioorg.2024.107103  0.126
2015 Sun W, Xie Z, Liu Y, Zhao D, Wu Z, Zhang D, Lv H, Tang S, Jin N, Jiang H, Tan M, Ding J, Luo C, Li J, Huang M, et al. JX06 selectively inhibits pyruvate dehydrogenase kinase PDK1 by a covalent cysteine modification. Cancer Research. PMID 26483203 DOI: 10.1158/0008-5472.Can-15-1023  0.125
2020 Yang Y, Zhang R, Li Z, Mei L, Wan S, Ding H, Chen Z, Xing J, Feng H, Han J, Jiang H, Zheng M, Luo C, Zhou B. Discovery of Highly Potent, Selective, and Orally Efficacious p300/CBP Histone Acetyltransferases Inhibitors. Journal of Medicinal Chemistry. PMID 31910017 DOI: 10.1021/acs.jmedchem.9b01721  0.125
2021 Gong J, Jiang S, Li Z, Pei H, Li Q, Yao D, Luo C. Distinct effects of the basal ganglia and cerebellum on the thalamocortical pathway in idiopathic generalized epilepsy. Human Brain Mapping. PMID 33830581 DOI: 10.1002/hbm.25444  0.125
2010 Li N, Thompson S, Schultz DC, Zhu W, Jiang H, Luo C, Lieberman PM. Discovery of selective inhibitors against EBNA1 via high throughput in silico virtual screening. Plos One. 5: e10126. PMID 20405039 DOI: 10.1371/Journal.Pone.0010126  0.125
2012 Chen F, Wang Y, Ai J, Zhan Z, Lv Y, Liang Z, Luo C, Mei D, Geng M, Duan W. O-linked triazolotriazines: potent and selective c-Met inhibitors. Chemmedchem. 7: 1276-85. PMID 22539497 DOI: 10.1002/cmdc.201200145  0.124
2021 Lu T, Li Y, Lu W, Spitters T, Fang X, Wang J, Cai S, Gao J, Zhou Y, Duan Z, Xiong H, Liu L, Li Q, Jiang H, Chen K, ... ... Luo C, et al. Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3. Acta Pharmaceutica Sinica. B. 11: 3206-3219. PMID 34729310 DOI: 10.1016/j.apsb.2021.04.015  0.124
2015 Huang Y, Yan J, Li Q, Li J, Gong S, Zhou H, Gan J, Jiang H, Jia GF, Luo C, Yang CG. Meclofenamic acid selectively inhibits FTO demethylation of m6A over ALKBH5. Nucleic Acids Research. 43: 373-84. PMID 25452335 DOI: 10.1093/nar/gku1276  0.124
2023 Lu L, Chen S, Yu M, Zhou R, Guo S, Chen JA, Wang H, Chen S, Luo C, Xie Q, Wang Y. Discovery of novel triazine derivatives as potent retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonists. European Journal of Medicinal Chemistry. 256: 115424. PMID 37167779 DOI: 10.1016/j.ejmech.2023.115424  0.123
2012 Chen B, Ye F, Yu L, Jia G, Huang X, Zhang X, Peng S, Chen K, Wang M, Gong S, Zhang R, Yin J, Li H, Yang Y, Liu H, ... ... Luo C, et al. Development of cell-active N6-methyladenosine RNA demethylase FTO inhibitor. Journal of the American Chemical Society. 134: 17963-71. PMID 23045983 DOI: 10.1021/ja3064149  0.123
2012 Li J, Dai CX, Sun H, Jin L, Guo CY, Cao W, Wu J, Tian HY, Luo C, Ye WC, Jiang RW. Protective effects and mechanisms of curcumin on podophyllotoxin toxicity in vitro and in vivo. Toxicology and Applied Pharmacology. 265: 190-9. PMID 23088858 DOI: 10.1016/J.Taap.2012.10.010  0.123
2017 Xing J, Lu W, Liu R, Wang Y, Xie Y, Zhang H, Shi Z, Jiang H, Liu YC, Chen K, Jiang H, Luo C, Zheng M. A Machine-learning-assisted Approach for Discovering Novel Inhibitors Targeting Bromodomain-containing Protein 4. Journal of Chemical Information and Modeling. PMID 28636361 DOI: 10.1021/acs.jcim.7b00098  0.123
2015 Xu Y, Liu X, Wang Y, Zhou N, Peng J, Gong L, Ren J, Luo C, Luo X, Jiang H, Chen K, Zheng M. Combinatorial Pharmacophore Modeling of Multidrug and Toxin Extrusion Transporter 1 Inhibitors: a Theoretical Perspective for Understanding Multiple Inhibitory Mechanisms. Scientific Reports. 5: 13684. PMID 26330298 DOI: 10.1038/srep13684  0.123
2013 Zhang R, Li X, Liang Z, Zhu K, Lu J, Kong X, Ouyang S, Li L, Zheng YG, Luo C. Theoretical insights into catalytic mechanism of protein arginine methyltransferase 1. Plos One. 8: e72424. PMID 23977297 DOI: 10.1371/journal.pone.0072424  0.123
2012 Kong X, Qin J, Li Z, Vultur A, Tong L, Feng E, Rajan G, Liu S, Lu J, Liang Z, Zheng M, Zhu W, Jiang H, Herlyn M, Liu H, ... ... Luo C, et al. Development of a novel class of B-Raf(V600E)-selective inhibitors through virtual screening and hierarchical hit optimization. Organic & Biomolecular Chemistry. 10: 7402-17. PMID 22875039 DOI: 10.1039/C2Ob26081F  0.123
2009 Sun WH, Chen GS, Ou XL, Yang Y, Luo C, Zhang Y, Shao Y, Xu HC, Xiao B, Xue YP, Zhou SM, Zhao QS, Ding GX. Inhibition of COX-2 and activation of peroxisome proliferator-activated receptor gamma synergistically inhibits proliferation and induces apoptosis of human pancreatic carcinoma cells. Cancer Letters. 275: 247-55. PMID 19056168 DOI: 10.1016/j.canlet.2008.10.023  0.122
2022 Wang S, Luo C, Li B, Zhang S, Liao W, Xin Q, Xu N, Xie W, Zhu Y, Zhang Y. LINC00472 inhibits cell migration by enhancing intercellular adhesion and regulates H3K27ac level via interacting with P300 in renal clear cell carcinoma. Cell Death Discovery. 8: 454. PMID 36371410 DOI: 10.1038/s41420-022-01243-7  0.122
2024 Zhang H, Xu D, Huang H, Jiang H, Hu L, Liu L, Sun G, Gao J, Li Y, Xia C, Chen S, Zhou H, Kong X, Wang M, Luo C. Discovery of a Covalent Inhibitor Selectively Targeting the Autophosphorylation Site of c-Src Kinase. Acs Chemical Biology. PMID 38513196 DOI: 10.1021/acschembio.4c00048  0.122
2023 Liu B, Yu X, Liu L, Wang L, Wang J, Huang Q, Xu Z, Luo C, Lou L, Huang W, Yang W. Modular Biomimetic Strategy Enabled Discovery of Simplified Pseudo-Natural Macrocyclic P-Glycoprotein Inhibitors Capable of Overcoming Multidrug Resistance. Journal of Medicinal Chemistry. PMID 36728755 DOI: 10.1021/acs.jmedchem.2c01424  0.122
2014 Xue K, Luo C, Zhang D, Yang T, Li J, Gong D, Chen L, Medina YI, Gotman J, Zhou D, Yao D. Diffusion tensor tractography reveals disrupted structural connectivity in childhood absence epilepsy. Epilepsy Research. 108: 125-38. PMID 24246142 DOI: 10.1016/J.Eplepsyres.2013.10.002  0.122
2011 Wang F, Liu D, Wang H, Luo C, Zheng M, Liu H, Zhu W, Luo X, Zhang J, Jiang H. Computational screening for active compounds targeting protein sequences: methodology and experimental validation. Journal of Chemical Information and Modeling. 51: 2821-2828. PMID 21955088 DOI: 10.1021/Ci200264H  0.122
2011 Chen L, Kong X, Liang Z, Ye F, Yu K, Dai W, Wu D, Luo C, Jiang H. Theoretical study of the mechanism of proton transfer in the esterase EstB from Burkholderia gladioli. The Journal of Physical Chemistry. B. 115: 13019-25. PMID 21910435 DOI: 10.1021/jp206297d  0.122
2017 Zhu MR, Du DH, Hu JC, Li LC, Liu JQ, Ding H, Kong XQ, Jiang HL, Chen KX, Luo C. Development of a high-throughput fluorescence polarization assay for the discovery of EZH2-EED interaction inhibitors. Acta Pharmacologica Sinica. PMID 28858300 DOI: 10.1038/aps.2017.59  0.121
2021 Luo C, Fan S, Yue L, Wan W, Zhang Y, Zhang B, Otomo C, Li Q, Lin T, Hu J, Xu P, Zhu M, Tao H, Chen Z, Li L, et al. Inhibition of autophagy by a small molecule through covalent modification of LC3. Angewandte Chemie (International Ed. in English). PMID 34590387 DOI: 10.1002/anie.202109464  0.121
2012 Liang Z, Ding X, Ai J, Kong X, Chen L, Chen L, Luo C, Geng M, Liu H, Chen K, Jiang H. Discovering potent inhibitors against c-Met kinase: molecular design, organic synthesis and bioassay. Organic & Biomolecular Chemistry. 10: 421-30. PMID 22108637 DOI: 10.1039/c1ob06186k  0.121
2016 Jiang S, Luo C, Liu Z, Hou C, Wang P, Dong L, Zhong C, Lai Y, Xia Y, Yao D. Altered Local Spontaneous Brain Activity in Juvenile Myoclonic Epilepsy: A Preliminary Resting-State fMRI Study. Neural Plasticity. 2016: 3547203. PMID 26823984 DOI: 10.1155/2016/3547203  0.121
2008 Luo C, Xie P, Marmorstein R. Identification of BRAF inhibitors through in silico screening. Journal of Medicinal Chemistry. 51: 6121-7. PMID 18783202 DOI: 10.1021/Jm800539G  0.121
2014 Wang L, Gao S, Jiang W, Luo C, Xu M, Bohlin L, Rosendahl M, Huang W. Antioxidative dietary compounds modulate gene expression associated with apoptosis, DNA repair, inhibition of cell proliferation and migration. International Journal of Molecular Sciences. 15: 16226-45. PMID 25226533 DOI: 10.3390/Ijms150916226  0.121
2011 Kong X, Ouyang S, Liang Z, Lu J, Chen L, Shen B, Li D, Zheng M, Li KK, Luo C, Jiang H. Catalytic mechanism investigation of lysine-specific demethylase 1 (LSD1): a computational study. Plos One. 6: e25444. PMID 21984927 DOI: 10.1371/journal.pone.0025444  0.12
2019 Chen Q, Liu J, Zhuang Y, Bai LP, Yuan Q, Zheng S, Liao K, Khan MA, Wu Q, Luo C, Liang L, Wang H, Li T. Identification of an IKKβ inhibitor for inhibition of inflammation in vivo and in vitro. Pharmacological Research. 104440. PMID 31479750 DOI: 10.1016/j.phrs.2019.104440  0.12
2021 Wang Y, Li X, Ge J, Liu M, Pang X, Liu J, Luo C, Xu Y, Zhao Q. The methyltransferase PRMT1 regulates γ-globin translation. The Journal of Biological Chemistry. 100417. PMID 33587951 DOI: 10.1016/j.jbc.2021.100417  0.12
2005 Luo C, He ML, Bohlin L. Is COX-2 a perpetrator or a protector? Selective COX-2 inhibitors remain controversial. Acta Pharmacologica Sinica. 26: 926-33. PMID 16038624 DOI: 10.1111/J.1745-7254.2005.00150.X  0.12
2010 Liang Z, Shi T, Ouyang S, Li H, Yu K, Zhu W, Luo C, Jiang H. Investigation of the catalytic mechanism of Sir2 enzyme with QM/MM approach: SN1 vs SN2? The Journal of Physical Chemistry. B. 114: 11927-33. PMID 20726530 DOI: 10.1021/jp1054183  0.12
2011 Luo C, Qiu C, Guo Z, Fang J, Li Q, Lei X, Xia Y, Lai Y, Gong Q, Zhou D, Yao D. Disrupted functional brain connectivity in partial epilepsy: a resting-state fMRI study. Plos One. 7: e28196. PMID 22242146 DOI: 10.1371/journal.pone.0028196  0.12
2024 Yu H, Luo C, Linghu R, Yang J, Wu H. Ezrin Contributes to the Damage of Airway Epithelial Barrier Related to Diabetes Mellitus. Journal of Inflammation Research. 17: 2609-2621. PMID 38689797 DOI: 10.2147/JIR.S449487  0.12
2024 Luo C, Mo L, Zeng Z, Jiang M, Chen BT. Artificial intelligence-assisted measurements of coronary computed tomography angiography parameters such as stenosis, flow reserve and fat attenuation for predicting major adverse cardiac events in patients with coronary arterial disease. Biomolecules & Biomedicine. PMID 38683171 DOI: 10.17305/bb.2024.10497  0.12
2024 Li Y, Zhu Y, Shang FF, Xu L, Jiang D, Sun B, Zhang L, Luo C, Zhang A, Zhang H, Ding C. Discovery of Urea Derivatives of Celastrol as Selective Peroxiredoxin 1 Inhibitors against Colorectal Cancer Cells. Journal of Medicinal Chemistry. PMID 38679872 DOI: 10.1021/acs.jmedchem.4c00023  0.12
2024 Luo C, Chen T, Cen K, Xie L, Dong X, Xiao X. Transition Metal (Co, V, W, Zr) Single-Atom Decorated Biphenylene for Enhancing the Sensing Performance of SF Decomposition Molecules. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 38666488 DOI: 10.1021/acs.langmuir.4c00035  0.12
2024 Zhang G, Zhang C, Cai M, Luo C, Zhu F, Liang Z. FuncPhos-STR: An integrated deep neural network for functional phosphosite prediction based on AlphaFold protein structure and dynamics. International Journal of Biological Macromolecules. 266: 131180. PMID 38552697 DOI: 10.1016/j.ijbiomac.2024.131180  0.12
2023 Xue F, Yang J, Luo C, Li D, Shi G, Song G, Li Y. Metagenomic insight into the biodegradation of biomass and alkaloids in the aging process of cigar. Bioresources and Bioprocessing. 10: 45. PMID 38647787 DOI: 10.1186/s40643-023-00667-y  0.12
2016 Luo C, Wang X, An C, Hwang CF, Miao W, Yang L, Xu M, Bai A, Deng S. Molecular inhibition mechanisms of cell migration and invasion by coix polysaccharides in A549 NSCLC cells via targeting S100A4. Molecular Medicine Reports. PMID 27922683 DOI: 10.3892/mmr.2016.5985  0.12
2022 Xu X, Wang M, Xu H, Liu N, Chen K, Luo C, Chen S, Chen H. Design, synthesis and biological evaluation of 2-aminopyridine derivatives as USP7 inhibitors. Bioorganic Chemistry. 129: 106128. PMID 36113266 DOI: 10.1016/j.bioorg.2022.106128  0.119
2020 Li G, Zheng YH, Xu L, Feng J, Tang HL, Luo C, Song YP, Chen XQ. BRD4 inhibitor nitroxoline enhances the sensitivity of multiple myeloma cells to bortezomib and by promoting mitochondrial pathway-mediated cell apoptosis. Therapeutic Advances in Hematology. 11: 2040620720932686. PMID 32551032 DOI: 10.1177/2040620720932686  0.119
2016 Zhao B, Li Y, Xu P, Dai Y, Luo C, Sun Y, Ai J, Geng M, Duan W. Discovery of Substituted 1H-Pyrazolo[3,4-b]pyridine Derivatives as Potent and Selective FGFR Kinase Inhibitors. Acs Medicinal Chemistry Letters. 7: 629-34. PMID 27326339 DOI: 10.1021/acsmedchemlett.6b00066  0.119
2015 Li Q, Cao W, Liao X, Chen Z, Yang T, Gong Q, Zhou D, Luo C, Yao D. Altered resting state functional network connectivity in children absence epilepsy. Journal of the Neurological Sciences. 354: 79-85. PMID 25982500 DOI: 10.1016/j.jns.2015.04.054  0.119
2015 Meng F, Cheng S, Ding H, Liu S, Liu Y, Zhu K, Chen S, Lu J, Xie Y, Li L, Liu R, Shi Z, Zhou Y, Liu YC, Zheng M, ... ... Luo C, et al. Discovery and optimization of novel, selective histone methyltransferase SET7 inhibitors by pharmacophore- and docking-based virtual screening. Journal of Medicinal Chemistry. PMID 26390175 DOI: 10.1021/acs.jmedchem.5b01154  0.119
2014 Chen L, Luo LF, Lu J, Li L, Liu YF, Wang J, Liu H, Song H, Jiang H, Chen SJ, Luo C, Li KK. FTY720 induces apoptosis of M2 subtype acute myeloid leukemia cells by targeting sphingolipid metabolism and increasing endogenous ceramide levels. Plos One. 9: e103033. PMID 25050888 DOI: 10.1371/journal.pone.0103033  0.119
2021 Xiong F, Ding X, Zhang H, Luo X, Chen K, Jiang H, Luo C, Xu H. Discovery of novel reversible monoacylglycerol lipase inhibitors via docking-based virtual screening. Bioorganic & Medicinal Chemistry Letters. 127986. PMID 33766770 DOI: 10.1016/j.bmcl.2021.127986  0.119
2021 Zhang H, He J, Hu G, Zhu F, Jiang H, Gao J, Zhou H, Lin H, Wang Y, Chen K, Meng F, Hao M, Zhao K, Luo C, Liang Z. Dynamics of Post-Translational Modification Inspires Drug Design in the Kinase Family. Journal of Medicinal Chemistry. PMID 34668699 DOI: 10.1021/acs.jmedchem.1c01076  0.119
2019 Xu H, Tang Z, Zuo Y, Xiong F, Chen K, Jiang H, Luo C, Zhang H. Molecular dynamics simulation revealed the intrinsic conformational change of cellular inhibitor of apoptosis protein-1. Journal of Biomolecular Structure & Dynamics. 1-15. PMID 30843765 DOI: 10.1080/07391102.2019.1591303  0.119
2015 Li J, Feng J, Luo C, Herman HY, Jiang RW. Absolute configuration of podophyllotoxone and its inhibitory activity against human prostate cancer cells. Chinese Journal of Natural Medicines. 13: 59-64. PMID 25660289 DOI: 10.1016/S1875-5364(15)60007-3  0.119
2021 Jiang S, Li H, Pei H, Liu L, Li Z, Chen Y, Li X, Li Q, Yao D, Luo C. Connective profiles and antagonism between dynamic and static connectivity underlying generalized epilepsy. Brain Structure & Function. PMID 33730218 DOI: 10.1007/s00429-021-02248-1  0.119
2024 Suo Y, Du D, Chen C, Zhu H, Wang X, Song N, Lu D, Yang Y, Li J, Wang J, Luo Z, Zhou B, Luo C, Zhou H. Uncovering PROTAC Sensitivity and Efficacy by Multidimensional Proteome Profiling: A Case for STAT3. Journal of Medicinal Chemistry. PMID 38466231 DOI: 10.1021/acs.jmedchem.3c02371  0.119
2022 Li SW, Wu Q, Xu H, Yao LG, Luo C, Wang H, Zhang H, Li XW, Guo YW. Ocellatuperoxides A-F, Uncommon Anti-Tumoral -Pyrone Peroxides from a Photosynthetic Mollusk . Marine Drugs. 20. PMID 36286413 DOI: 10.3390/md20100590  0.119
2018 Luo C, Wu D, Magawa G, Omodo J, Xue C, Sun Y, Liu D, Xie C, Wang Y, Frenz C, Deng S. Inhibition of migration and invasion of hepatocarcinoma HepG2 cells by dietary saponins via targeting HIF-1α. Anti-Cancer Agents in Medicinal Chemistry. PMID 29318977 DOI: 10.2174/1871520618666180110141827  0.119
2022 Lu H, Lu T, Zu S, Duan Z, Guang Y, Li Q, Ma J, Chen D, Li B, Lu W, Jiang H, Luo C, Ye D, Chen K, Lin H. Discovery of a highly potent CECR2 bromodomain inhibitor with 7H-pyrrolo[2,3-d] pyrimidine scaffold. Bioorganic Chemistry. 123: 105768. PMID 35378372 DOI: 10.1016/j.bioorg.2022.105768  0.118
2017 Wang X, Luo C, Cheng X, Lu M. Lithium and an EPAC-specific inhibitor ESI-09 synergistically suppress pancreatic cancer cell proliferation and survival. Acta Biochimica Et Biophysica Sinica. 1-8. PMID 28475672 DOI: 10.1093/abbs/gmx045  0.118
2023 Wang L, Dou X, Chen S, Yu X, Huang X, Zhang L, Chen Y, Wang J, Yang K, Bugno J, Pitroda S, Ding X, Piffko A, Si W, Chen C, ... ... Luo C, et al. YTHDF2 inhibition potentiates radiotherapy antitumor efficacy. Cancer Cell. PMID 37236197 DOI: 10.1016/j.ccell.2023.04.019  0.117
2014 Luo C, Li Y, Yang L, Zheng Y, Long J, Jia J, Xiao S, Liu J. Activation of Erk and p53 regulates copper oxide nanoparticle-induced cytotoxicity in keratinocytes and fibroblasts. International Journal of Nanomedicine. 9: 4763-72. PMID 25336953 DOI: 10.2147/IJN.S67688  0.117
2012 Luo C, Li Q, Xia Y, Lei X, Xue K, Yao Z, Lai Y, Martínez-Montes E, Liao W, Zhou D, Valdes-Sosa PA, Gong Q, Yao D. Resting state basal ganglia network in idiopathic generalized epilepsy. Human Brain Mapping. 33: 1279-94. PMID 21520351 DOI: 10.1002/hbm.21286  0.117
2022 Li J, Liu T, Song Y, Wang M, Liu L, Zhu H, Li Q, Lin J, Jiang H, Chen K, Zhao K, Wang M, Zhou H, Lin H, Luo C. Discovery of Small-Molecule Degraders of the CDK9-Cyclin T1 Complex for Targeting Transcriptional Addiction in Prostate Cancer. Journal of Medicinal Chemistry. PMID 35925880 DOI: 10.1021/acs.jmedchem.2c00257  0.117
2017 Luo C, Chen S, Xu N, Sai WB, Zhao W, Li YC, Hu XJ, Tian H, Gao XD, Yao WB. Establishment of a fluorescence-based method to evaluate endocytosis of desialylated glycoproteins in vitro. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 88: 87-94. PMID 28095357 DOI: 10.1016/j.biopha.2016.12.085  0.116
2019 Qin Y, Jiang S, Zhang Q, Dong L, Jia X, He H, Yao Y, Yang H, Zhang T, Luo C, Yao D. BOLD-fMRI activity informed by network variation of scalp EEG in juvenile myoclonic epilepsy. Neuroimage. Clinical. 22: 101759. PMID 30897433 DOI: 10.1016/j.nicl.2019.101759  0.116
2018 Klugah-Brown B, Luo C, He H, Jiang S, Armah GK, Wu Y, Li J, Yin W, Yao D. Altered Dynamic Functional Network Connectivity in Frontal Lobe Epilepsy. Brain Topography. PMID 30255350 DOI: 10.1007/s10548-018-0678-z  0.116
2014 Tian HY, Yuan XF, Jin L, Li J, Luo C, Ye WC, Jiang RW. A bufadienolide derived androgen receptor antagonist with inhibitory activities against prostate cancer cells. Chemico-Biological Interactions. 207: 16-22. PMID 24211617 DOI: 10.1016/J.Cbi.2013.10.020  0.116
2019 Jiang Y, Xu L, Li X, Tang Y, Wang P, Li C, Yao D, Wang J, Luo C. Common increased hippocampal volume but specific changes in functional connectivity in schizophrenia patients in remission and non-remission following electroconvulsive therapy: A preliminary study. Neuroimage. Clinical. 24: 102081. PMID 31734526 DOI: 10.1016/j.nicl.2019.102081  0.116
2024 Qian H, Ding CH, Liu F, Chen SJ, Huang CK, Xiao MC, Hong XL, Wang MC, Yan FZ, Ding K, Cui YL, Zheng BN, Ding J, Luo C, Zhang X, et al. SRY-Box transcription factor 9 triggers YAP nuclear entry via direct interaction in tumors. Signal Transduction and Targeted Therapy. 9: 96. PMID 38653754 DOI: 10.1038/s41392-024-01805-4  0.116
2011 Liao W, Zhang Z, Pan Z, Mantini D, Ding J, Duan X, Luo C, Wang Z, Tan Q, Lu G, Chen H. Default mode network abnormalities in mesial temporal lobe epilepsy: a study combining fMRI and DTI. Human Brain Mapping. 32: 883-95. PMID 20533558 DOI: 10.1002/Hbm.21076  0.116
2023 Cao Y, Wu B, Xu Y, Wang M, Wu X, Liang X, Lin J, Li Z, Lin H, Luo C, Chen S. Discovery of GPX4 inhibitors through FP-based high-throughput screening. European Journal of Medicinal Chemistry. 265: 116044. PMID 38145603 DOI: 10.1016/j.ejmech.2023.116044  0.115
2013 Lu X, Liu W, Wu J, Li M, Wang J, Wu J, Luo C. A polysaccharide fraction of adlay seed (Coixlachryma-jobi L.) induces apoptosis in human non-small cell lung cancer A549 cells. Biochemical and Biophysical Research Communications. 430: 846-51. PMID 23200838 DOI: 10.1016/j.bbrc.2012.11.058  0.115
2013 Liang Z, Ai J, Ding X, Peng X, Zhang D, Zhang R, Wang Y, Liu F, Zheng M, Jiang H, Liu H, Geng M, Luo C. Anthraquinone Derivatives as Potent Inhibitors of c-Met Kinase and the Extracellular Signaling Pathway. Acs Medicinal Chemistry Letters. 4: 408-13. PMID 24900685 DOI: 10.1021/ml4000047  0.115
2012 Zhang D, Ai J, Liang Z, Li C, Peng X, Ji Y, Jiang H, Geng M, Luo C, Liu H. Discovery of novel 2-aminopyridine-3-carboxamides as c-Met kinase inhibitors. Bioorganic & Medicinal Chemistry. 20: 5169-80. PMID 22863529 DOI: 10.1016/j.bmc.2012.07.007  0.115
2020 Min W, Hou Z, Zhang F, Xie S, Yuan K, Dong H, Wang L, Qi L, Luo C, Ding H, Yang P. Computational discovery and biological evaluation of novel inhibitors targeting histone-lysine N-methyltransferase SET7. Bioorganic & Medicinal Chemistry. 115372. PMID 32088124 DOI: 10.1016/j.bmc.2020.115372  0.115
2024 Shi F, Shang L, Zhou M, Lv C, Li Y, Luo C, Liu N, Lu J, Tang M, Luo X, Xu J, Fan J, Zhou J, Gao Q, Wu W, et al. Epstein-Barr virus-driven metabolic alterations contribute to the viral lytic reactivation and tumor progression in nasopharyngeal carcinoma. Journal of Medical Virology. 96: e29634. PMID 38682578 DOI: 10.1002/jmv.29634  0.115
2012 Jiang J, Lu J, Lu D, Liang Z, Li L, Ouyang S, Kong X, Jiang H, Shen B, Luo C. Investigation of the acetylation mechanism by GCN5 histone acetyltransferase. Plos One. 7: e36660. PMID 22574209 DOI: 10.1371/journal.pone.0036660  0.115
2023 Li H, Shi H, Jiang S, Hou C, Wu H, Yao G, Yao D, Luo C. Atypical Hierarchical Connectivity Revealed by Stepwise Functional Connectivity in Aging. Bioengineering (Basel, Switzerland). 10. PMID 37892896 DOI: 10.3390/bioengineering10101166  0.115
2019 Wang Y, Qin Y, Li H, Yao D, Sun B, Li Z, Li X, Dai Y, Wen C, Zhang L, Zhang C, Zhu T, Luo C. Abnormal Functional Connectivity in Cognitive Control Network, Default Mode Network, and Visual Attention Network in Internet Addiction: A Resting-State fMRI Study. Frontiers in Neurology. 10: 1006. PMID 31620077 DOI: 10.3389/fneur.2019.01006  0.114
2013 Xie Y, Chen X, Qin J, Kong X, Ye F, Jiang Y, Liu H, Jiang H, Marmorstein R, Luo C. Identification and synthesis of N-(thiophen-2-yl) benzamide derivatives as BRAF(V600E) inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 2306-12. PMID 23489628 DOI: 10.1016/j.bmcl.2013.02.072  0.114
2018 Liang Z, Hu J, Yan W, Jiang H, Hu G, Luo C. Deciphering the role of dimer interface in intrinsic dynamics and allosteric pathways underlying the functional transformation of DNMT3A. Biochimica Et Biophysica Acta. PMID 29674125 DOI: 10.1016/j.bbagen.2018.04.015  0.114
2018 Liang Z, Hu J, Yan W, Jiang H, Hu G, Luo C. Deciphering the role of dimer interface in intrinsic dynamics and allosteric pathways underlying the functional transformation of DNMT3A. Biochimica Et Biophysica Acta. PMID 29674125 DOI: 10.1016/j.bbagen.2018.04.015  0.114
2018 Zhong C, Liu R, Luo C, Jiang S, Dong L, Peng R, Guo F, Wang P. Altered Structural and Functional Connectivity of Juvenile Myoclonic Epilepsy: An fMRI Study. Neural Plasticity. 2018: 7392187. PMID 29681927 DOI: 10.1155/2018/7392187  0.114
2016 Yan W, Wang X, Dai Y, Zhao B, Yang X, Fan J, Gao Y, Meng F, Wang Y, Luo C, Ai J, Geng MY, Duan W. Discovery of 3-(5'-Substituted)-benzimidazole-5-(1-(3,5-dichloropyridin-4-yl)ethoxy)-1H-indazoles as Potent Fibroblast Growth Factor Receptor Inhibitors: Design, Synthesis and Biological Evaluation. Journal of Medicinal Chemistry. PMID 27348537 DOI: 10.1021/acs.jmedchem.6b00056  0.114
2020 Jiang S, Pei H, Huang Y, Chen Y, Liu L, Li J, He H, Yao D, Luo C. Dynamic Temporospatial Patterns of Functional Connectivity and Alterations in Idiopathic Generalized Epilepsy. International Journal of Neural Systems. 2050065. PMID 33161788 DOI: 10.1142/S0129065720500653  0.114
2011 Shen Q, Xiong B, Zheng M, Luo X, Luo C, Liu X, Du Y, Li J, Zhu W, Shen J, Jiang H. Knowledge-based scoring functions in drug design: 2. Can the knowledge base be enriched? Journal of Chemical Information and Modeling. 51: 386-97. PMID 21192670 DOI: 10.1021/ci100343j  0.114
2017 Ma S, Jiang S, Peng R, Zhu Q, Sun H, Li J, Jia X, Goldberg I, Yu L, Luo C. Altered Local Spatiotemporal Consistency of Resting-State BOLD Signals in Patients with Generalized Tonic-Clonic Seizures. Frontiers in Computational Neuroscience. 11: 90. PMID 29033811 DOI: 10.3389/fncom.2017.00090  0.114
2021 Cao X, Huang H, Zhang B, Jiang Y, He H, Duan M, Jiang S, Tan Y, Yao D, Li C, Luo C. Surface-Based Spontaneous Oscillation in Schizophrenia: A Resting-State Functional Magnetic Resonance Imaging Study. Frontiers in Human Neuroscience. 15: 750879. PMID 34938168 DOI: 10.3389/fnhum.2021.750879  0.114
2009 Zhang C, Yang N, Yang CH, Ding HS, Luo C, Zhang Y, Wu MJ, Zhang XW, Shen X, Jiang HL, Meng LH, Ding J. S9, a novel anticancer agent, exerts its anti-proliferative activity by interfering with both PI3K-Akt-mTOR signaling and microtubule cytoskeleton. Plos One. 4: e4881. PMID 19293927 DOI: 10.1371/Journal.Pone.0004881  0.114
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2013 Luo C, Li Y, Wang H, Cui Y, Feng Z, Li H, Li Y, Wang Y, Wurtz K, Weber P, Long J, Liu J. Hydroxytyrosol promotes superoxide production and defects in autophagy leading to anti-proliferation and apoptosis on human prostate cancer cells. Current Cancer Drug Targets. 13: 625-39. PMID 23597197 DOI: 10.2174/15680096113139990035  0.113
2019 Peng J, Li J, Huang J, Xu P, Huang H, Liu Y, Yu L, Yang Y, Zhou B, Jiang H, Chen K, Dang Y, Zhang Y, Luo C, Li G. p300/CBP inhibitor A-485 alleviates acute liver injury by regulating macrophage activation and polarization. Theranostics. 9: 8344-8361. PMID 31754401 DOI: 10.7150/Thno.30707  0.113
2022 Pu DB, Guo SQ, Ni DX, Lin J, Gao JB, Li XN, Zhang RH, Li XL, Luo C, Chen SJ, Xiao WL. Spiroarborin, an -Clerodane Homodimer from as an Inhibitor of the Eleven-Nineteen Leukemia (ENL) Protein by Targeting the YEATS Domain. Journal of Natural Products. 85: 317-326. PMID 35029993 DOI: 10.1021/acs.jnatprod.1c00775  0.113
2018 Li Z, Xue Y, Li M, Guo Q, Sang Y, Wang C, Luo C. The Antioxidation of Different Fractions of Dill (Anethum graveolens) and Their Influences on Cytokines in Macrophages RAW264.7. Journal of Oleo Science. PMID 30429445 DOI: 10.5650/jos.ess18134  0.113
2015 Yan W, Huang Z, Wang Z, Cao S, Tong L, Zhang T, Wang C, Zhou L, Ding J, Luo C, Zhou J, Xie H, Duan W. Discovery of 1,3-Diaryl-pyridones as Potent VEGFR-2 Inhibitors: Design, Synthesis and Biological Evaluation. Chemical Biology & Drug Design. PMID 26669707 DOI: 10.1111/Cbdd.12703  0.113
2018 Zhang R, Wang J, Zhao L, Liu S, Du D, Ding H, Chen S, Yue L, Liu YC, Zhang C, Liu H, Luo C. Identification of novel inhibitors of histone acetyltransferase hMOF through high throughput screening. European Journal of Medicinal Chemistry. 157: 867-876. PMID 30145373 DOI: 10.1016/j.ejmech.2018.08.026  0.113
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2007 Zhang L, Liu W, Hu T, Du L, Luo C, Chen K, Shen X, Jiang H. Structural basis for catalytic and inhibitory mechanisms of beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ). The Journal of Biological Chemistry. 283: 5370-9. PMID 18093984 DOI: 10.1074/jbc.M705566200  0.113
2022 Jiang C, Sun J, Li R, Yan S, Chen W, Guo L, Qin G, Wang P, Luo C, Huang W, Zhang Q, Fernie AR, Jackson D, Li X, Yan J. A reactive oxygen species burst causes haploid induction in maize. Molecular Plant. PMID 35395409 DOI: 10.1016/j.molp.2022.04.001  0.113
2016 Hu H, Luo C, Zheng YG. Transient Kinetics Define a Complete Kinetic Model for Protein Arginine Methyltransferase 1. The Journal of Biological Chemistry. PMID 27834681 DOI: 10.1074/jbc.M116.757625  0.112
2015 Jiang J, Zheng C, Zhu K, Liu J, Sun N, Wang C, Jiang H, Zhu J, Luo C, Zhou Y. Quantum chemistry calculation-aided structural optimization of combretastatin A-4-like tubulin polymerization inhibitors: improved stability and biological activity. Journal of Medicinal Chemistry. 58: 2538-46. PMID 25689111 DOI: 10.1021/acs.jmedchem.5b00118  0.112
2024 Jiang S, Pei H, Chen J, Li H, Liu Z, Wang Y, Gong J, Wang S, Li Q, Duan M, Calhoun VD, Yao D, Luo C. Striatum- and Cerebellum-Modulated Epileptic Networks Varying Across States with and without Interictal Epileptic Discharges. International Journal of Neural Systems. 2450017. PMID 38372049 DOI: 10.1142/S0129065724500175  0.112
2020 Meng F, Liang Z, Zhao K, Luo C. Drug design targeting active posttranslational modification protein isoforms. Medicinal Research Reviews. PMID 33355944 DOI: 10.1002/med.21774  0.112
2015 Li JL, Gao LX, Meng FW, Tang CL, Zhang RJ, Li JY, Luo C, Li J, Zhao WM. PTP1B inhibitors from stems of Angelica keiskei (Ashitaba). Bioorganic & Medicinal Chemistry Letters. 25: 2028-32. PMID 25891102 DOI: 10.1016/j.bmcl.2015.04.003  0.112
2017 Liu Y, Xie Z, Zhao D, Zhu J, Mao F, Tang S, Xu H, Luo C, Geng MY, Huang M, Li J. Development of the First Generation of Disulfide-Based Subtype-Selective and Potent Covalent Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors. Journal of Medicinal Chemistry. PMID 28230989 DOI: 10.1021/acs.jmedchem.6b01245  0.112
2020 Yang J, Zou Y, Wu J, Chen B, Luo C, Chen X, Shen H, Luo L. The Long Noncoding RNA Contributes to Proliferation and Epithelial-to-Mesenchymal Transition of Osteosarcoma. Cancer Biotherapy & Radiopharmaceuticals. PMID 33085924 DOI: 10.1089/cbr.2019.3433  0.111
2021 Huang HM, Zhou XR, Liu YJ, Fan SJ, Liao LP, Huang J, Shi CC, Yu L, Pen JJ, Luo C, Zhang YY, Li GM. Histone deacetylase inhibitor givinostat alleviates liver fibrosis by regulating hepatic stellate cell activation. Molecular Medicine Reports. 23. PMID 33649839 DOI: 10.3892/mmr.2021.11944  0.111
2019 Wen X, Dong L, Chen J, Xiang J, Yang J, Li H, Liu X, Luo C, Yao D. Detecting the Information of Functional Connectivity Networks in Normal Aging Using Deep Learning From a Big Data Perspective. Frontiers in Neuroscience. 13: 1435. PMID 32009894 DOI: 10.3389/fnins.2019.01435  0.111
2020 Li XW, Wu Q, Li SW, Xu H, Wang H, Hu P, Zhang H, Luo C, Chen KX, Nay B, Guo YW. Complex Polypropionates from a South China Sea Photosynthetic Mollusk: Isolation and Biomimetic Synthesis Highlighting Novel Rearrangements. Angewandte Chemie (International Ed. in English). PMID 32277730 DOI: 10.1002/anie.202003643  0.111
2020 Li Z, Li X, Su MB, Gao LX, Zhou YB, Yuan B, Lyu X, Yan Z, Hu C, Zhang H, Luo C, Chen Z, Li J, Zhao Y. Discovery of a potent and selective NF-κB-inducing kinase (NIK) inhibitor that has anti-inflammatory effects in vitro and in vivo. Journal of Medicinal Chemistry. PMID 32216342 DOI: 10.1021/acs.jmedchem.0c00396  0.111
2014 Luo C, An D, Yao D, Gotman J. Patient-specific connectivity pattern of epileptic network in frontal lobe epilepsy. Neuroimage. Clinical. 4: 668-75. PMID 24936418 DOI: 10.1016/J.Nicl.2014.04.006  0.11
2012 Xu Z, Yan G, Wang G, Li B, Zhu J, Sun P, Zhang X, Luo C, Wang H, Zhu W. Combining pharmacophore, docking and substructure search approaches to identify and optimize novel B-RafV600E inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 5428-37. PMID 22858139 DOI: 10.1016/j.bmcl.2012.07.039  0.11
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2021 Liu X, Yang H, Becker B, Huang X, Luo C, Meng C, Biswal B. Disentangling age- and disease-related alterations in schizophrenia brain network using structural equation modeling: A graph theoretical study based on minimum spanning tree. Human Brain Mapping. PMID 33960579 DOI: 10.1002/hbm.25403  0.11
2022 Qin Y, Li S, Yao D, Luo C. Causality Analysis to the Abnormal Subcortical-Cortical Connections in Idiopathic-Generalized Epilepsy. Frontiers in Neuroscience. 16: 925968. PMID 35844218 DOI: 10.3389/fnins.2022.925968  0.11
2018 Ye F, Kong X, Zhang H, Liu Y, Shao Z, Jin J, Cai Y, Zhang R, Li L, Zhang YW, Liu YC, Zhang C, Xie W, Yu K, Ding H, ... ... Luo C, et al. Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA methyltransferase-1 (DNMT1). Acs Chemical Biology. PMID 29381856 DOI: 10.1021/Acschembio.7B00890  0.11
2017 Cao W, Zhang Y, Hou C, Yang F, Gong J, Jiang S, Huang Y, Xiao R, Luo C, Wang X, Yao D. Abnormal asymmetry in benign epilepsy with unilateral and bilateral centrotemporal spikes: A combined fMRI and DTI study. Epilepsy Research. 135: 56-63. PMID 28623837 DOI: 10.1016/j.eplepsyres.2017.06.004  0.11
2017 Gong J, Luo C, Chang X, Zhang R, Klugah-Brown B, Guo L, Xu P, Yao D. White Matter Connectivity Pattern Associate with Characteristics of Scalp EEG Signals. Brain Topography. PMID 28785973 DOI: 10.1007/s10548-017-0581-z  0.11
2014 Zhang X, Ouyang S, Kong X, Liang Z, Lu J, Zhu K, Zhao D, Zheng M, Jiang H, Liu X, Marmorstein R, Luo C. Catalytic mechanism of histone acetyltransferase p300: from the proton transfer to acetylation reaction. The Journal of Physical Chemistry. B. 118: 2009-19. PMID 24521098 DOI: 10.1021/Jp409778E  0.109
2018 Zhao YH, Liu NW, Ke CC, Liu BW, Chen YA, Luo C, Zhang Q, Xia ZY, Liu RS. Combined treatment of sodium ferulate, n-butylidenephthalide, and ADSCs rehabilitates neurovascular unit in rats after photothrombotic stroke. Journal of Cellular and Molecular Medicine. PMID 30421523 DOI: 10.1111/jcmm.13894  0.109
2014 Liu L, Zhang J, Li M, Zhang X, Zhang J, Li Z, Wang L, Wu J, Luo C. Inhibition of HepG2 cell proliferation by ursolic acid and polysaccharides via the downregulation of cyclooxygenase-2. Molecular Medicine Reports. 9: 2505-11. PMID 24638056 DOI: 10.3892/mmr.2014.2059  0.109
2013 Li J, Sun H, Jin L, Cao W, Zhang J, Guo CY, Ding K, Luo C, Ye WC, Jiang RW. Alleviation of podophyllotoxin toxicity using coexisting flavonoids from Dysosma versipellis. Plos One. 8: e72099. PMID 23991049 DOI: 10.1371/journal.pone.0072099  0.109
2014 Kuo CY, Li X, Kong XQ, Luo C, Chang CC, Chung Y, Shih HM, Li KK, Ann DK. An arginine-rich motif of ring finger protein 4 (RNF4) oversees the recruitment and degradation of the phosphorylated and SUMOylated Krüppel-associated box domain-associated protein 1 (KAP1)/TRIM28 protein during genotoxic stress. The Journal of Biological Chemistry. 289: 20757-72. PMID 24907272 DOI: 10.1074/jbc.M114.555672  0.109
2018 Shao J, Meng C, Tahmasian M, Brandl F, Yang Q, Luo G, Luo C, Yao D, Gao L, Riedl V, Wohlschläger A, Sorg C. Common and distinct changes of default mode and salience network in schizophrenia and major depression. Brain Imaging and Behavior. PMID 29460166 DOI: 10.1007/s11682-018-9838-8  0.109
2019 Shi C, Zhang Y, Wang T, Lu W, Zhang S, Guo B, Chen Q, Luo C, Zhou XL, Yang Y. Design, Synthesis and Biological Evaluation of Novel DNA Gyrase-Inhibiting Spiropyrimidinetriones as Potent Antibiotics for Treatment of Infections Caused by Multidrug-Resistant Gram-Positive Bacteria. Journal of Medicinal Chemistry. PMID 30698430 DOI: 10.1021/acs.jmedchem.8b01750  0.109
2021 Jiang Y, Wang Y, Huang H, He H, Tang Y, Su W, Xu L, Wei Y, Zhang T, Hu H, Wang J, Yao D, Wang J, Luo C. Antipsychotics Effects on Network-Level Reconfiguration of Cortical Morphometry in First-Episode Schizophrenia. Schizophrenia Bulletin. PMID 34313782 DOI: 10.1093/schbul/sbab082  0.109
2013 Zhang R, Lu J, Kong X, Jin L, Luo C. Targeting epigenetics in nervous system disease. Cns & Neurological Disorders Drug Targets. 12: 126-41. PMID 23244434 DOI: 10.2174/1871527311312010018  0.109
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2023 Jiang GH, Wang G, Luo C, Wang YF, Qiu JF, Peng RJ, Sima YH, Xu SQ. Mechanism of hyperproteinemia-induced damage to female reproduction in a genetic silkworm model. Iscience. 26: 107860. PMID 37752953 DOI: 10.1016/j.isci.2023.107860  0.088
2018 Jiang Y, Luo C, Li X, Duan M, He H, Chen X, Yang H, Gong J, Chang X, Woelfer M, Biswal BB, Yao D. Progressive Reduction in Gray Matter in Patients with Schizophrenia Assessed with MR Imaging by Using Causal Network Analysis. Radiology. 287: 729. PMID 29668409 DOI: 10.1148/Radiol.2018184005  0.088
2021 Wang H, Mei Y, Luo C, Huang Q, Wang Z, Lu GM, Qin L, Sun Z, Huang CW, Yang ZW, Chen J, Yin W, Qian CN, Zeng J, Chen L, et al. Single-cell analyses reveal mechanisms of cancer stem cell maintenance and epithelial-mesenchymal transition in recurrent bladder cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34526362 DOI: 10.1158/1078-0432.CCR-20-4796  0.088
2017 Dong D, Wang Y, Chang X, Jiang Y, Klugah-Brown B, Luo C, Yao D. Shared abnormality of white matter integrity in schizophrenia and bipolar disorder: A comparative voxel-based meta-analysis. Schizophrenia Research. PMID 28082140 DOI: 10.1016/j.schres.2017.01.005  0.088
2014 Li S, Xiong B, Xu Y, Lu T, Luo X, Luo C, Shen J, Chen K, Zheng M, Jiang H. Mechanism of the All-α to All-β Conformational Transition of RfaH-CTD: Molecular Dynamics Simulation and Markov State Model. Journal of Chemical Theory and Computation. 10: 2255-64. PMID 26580748 DOI: 10.1021/ct5002279  0.088
2013 Li J, Liu X, Li S, Wang Y, Zhou N, Luo C, Luo X, Zheng M, Jiang H, Chen K. Identification of novel small molecules as inhibitors of hepatitis C virus by structure-based virtual screening. International Journal of Molecular Sciences. 14: 22845-56. PMID 24264035 DOI: 10.3390/ijms141122845  0.088
2015 Luo C, Li Y, Yang L, Wang X, Long J, Liu J. Superparamagnetic iron oxide nanoparticles exacerbate the risks of reactive oxygen species-mediated external stresses. Archives of Toxicology. 89: 357-69. PMID 24847785 DOI: 10.1007/s00204-014-1267-x  0.088
2019 Chen X, Xu K, Yang Y, Wang Q, Jiang H, Guo X, Chen X, Yang J, Luo C. Altered Default Mode Network Dynamics in Civil Aviation Pilots. Frontiers in Neuroscience. 13: 1406. PMID 31992967 DOI: 10.3389/fnins.2019.01406  0.088
2017 Ju J, Chen A, Deng Y, Liu M, Wang Y, Wang Y, Nie M, Wang C, Ding H, Yao B, Gui T, Li X, Xu Z, Ma C, Song Y, ... ... Luo C, et al. NatD promotes lung cancer progression by preventing histone H4 serine phosphorylation to activate Slug expression. Nature Communications. 8: 928. PMID 29030587 DOI: 10.1038/S41467-017-00988-5  0.088
2017 Zou Y, Huang Y, Yang J, Wu J, Luo C. miR-34a is downregulated in human osteosarcoma stem-like cells and promotes invasion, tumorigenic ability and self-renewal capacity. Molecular Medicine Reports. PMID 28260055 DOI: 10.3892/mmr.2017.6187  0.088
2019 Gong J, Luo C, Li X, Jiang S, Khundrakpam BS, Duan M, Chen X, Yao D. Evaluation of functional connectivity in subdivisions of the thalamus in schizophrenia. The British Journal of Psychiatry : the Journal of Mental Science. 1-9. PMID 30791964 DOI: 10.1192/bjp.2018.299  0.087
2019 Gong J, Luo C, Li X, Jiang S, Khundrakpam BS, Duan M, Chen X, Yao D. Evaluation of functional connectivity in subdivisions of the thalamus in schizophrenia. The British Journal of Psychiatry : the Journal of Mental Science. 1-9. PMID 30791964 DOI: 10.1192/bjp.2018.299  0.087
2020 Xie Q, Li F, Shen K, Luo C, Song G. LOXL1-AS1/miR-515-5p/STAT3 Positive Feedback Loop Facilitates Cell Proliferation and Migration in Atherosclerosis. Journal of Cardiovascular Pharmacology. 76: 151-158. PMID 32453072 DOI: 10.1097/FJC.0000000000000853  0.087
2014 Jiang Y, Lu J, Wang Y, Zeng F, Wang H, Peng H, Huang M, Jiang H, Luo C, Huang Y. Molecular-dynamics-simulation-driven design of a protease-responsive probe for in-vivo tumor imaging. Advanced Materials (Deerfield Beach, Fla.). 26: 8174-8. PMID 25338710 DOI: 10.1002/adma.201403547  0.087
2011 Luo C, Urgard E, Vooder T, Metspalu A. The role of COX-2 and Nrf2/ARE in anti-inflammation and antioxidative stress: Aging and anti-aging. Medical Hypotheses. 77: 174-8. PMID 21530094 DOI: 10.1016/j.mehy.2011.04.002  0.087
2016 Dong L, Li H, He Z, Jiang S, Klugah-Brown B, Chen L, Wang P, Tan S, Luo C, Yao D. Altered local spontaneous activity in frontal lobe epilepsy: a resting-state functional magnetic resonance imaging study. Brain and Behavior. 6: e00555. PMID 27843705 DOI: 10.1002/brb3.555  0.087
2022 Yimamu Y, Yang X, Chen J, Luo C, Xiao W, Guan H, Wang D. The Development of a Gleason Score-Related Gene Signature for Predicting the Prognosis of Prostate Cancer. Journal of Clinical Medicine. 11. PMID 36498737 DOI: 10.3390/jcm11237164  0.087
2015 Hu L, Lu J, Cheng J, Rao Q, Li Z, Hou H, Lou Z, Zhang L, Li W, Gong W, Liu M, Sun C, Yin X, Li J, Tan X, ... ... Luo C, et al. Structural insight into substrate preference for TET-mediated oxidation. Nature. PMID 26524525 DOI: 10.1038/Nature15713  0.087
2021 Jiang Y, Duan M, He H, Yao D, Luo C. Structural and Functional MRI Brain Changes in Patients with Schizophrenia Following Electroconvulsive Therapy: A Systematic Review. Current Neuropharmacology. PMID 34370638 DOI: 10.2174/1570159X19666210809101248  0.087
2024 Wang Z, Fan F, Li Z, Ye F, Wang Q, Gao R, Qiu J, Lv Y, Lin M, Xu W, Luo C, Yu X. Structural insights into the functional mechanism of the ubiquitin ligase E6AP. Nature Communications. 15: 3531. PMID 38670961 DOI: 10.1038/s41467-024-47586-w  0.087
2015 Hou F, Wang L, Wang H, Gu J, Li M, Zhang J, Ling X, Gao X, Luo C. Elevated gene expression of S100A12 is correlated with the predominant clinical inflammatory factors in patients with bacterial pneumonia. Molecular Medicine Reports. 11: 4345-52. PMID 25650963 DOI: 10.3892/mmr.2015.3295  0.087
2012 Sun F, Ding Y, Ji Q, Liang Z, Deng X, Wong CC, Yi C, Zhang L, Xie S, Alvarez S, Hicks LM, Luo C, Jiang H, Lan L, He C. Protein cysteine phosphorylation of SarA/MgrA family transcriptional regulators mediates bacterial virulence and antibiotic resistance. Proceedings of the National Academy of Sciences of the United States of America. 109: 15461-6. PMID 22927394 DOI: 10.1073/Pnas.1205952109  0.086
2006 Luo C, Wang X, Long J, Liu J. An NADH-tetrazolium-coupled sensitive assay for malate dehydrogenase in mitochondria and crude tissue homogenates. Journal of Biochemical and Biophysical Methods. 68: 101-11. PMID 16740313 DOI: 10.1016/J.JBBM.2006.04.003  0.086
2022 Duan Y, Zhao W, Luo C, Liu X, Jiang H, Tang Y, Liu C, Yao D. Identifying and Predicting Autism Spectrum Disorder Based on Multi-Site Structural MRI With Machine Learning. Frontiers in Human Neuroscience. 15: 765517. PMID 35273484 DOI: 10.3389/fnhum.2021.765517  0.086
2022 Ji C, Xu W, Ding H, Chen Z, Shi C, Han J, Yu L, Qiao N, Zhang Y, Cao X, Zhou X, Cheng H, Feng H, Luo C, Li Z, et al. The p300 inhibitor A-485 exerts antitumor activity in growth hormone pituitary adenoma. The Journal of Clinical Endocrinology and Metabolism. PMID 35247260 DOI: 10.1210/clinem/dgac128  0.086
2013 Xia Y, Luo C, Dai S, Yao D. Increased EphA/ephrinA expression in hippocampus of pilocarpine treated mouse. Epilepsy Research. 105: 20-9. PMID 23352741 DOI: 10.1016/j.eplepsyres.2013.01.001  0.086
2021 Wang Y, Jiang Y, Collin G, Liu D, Su W, Xu L, Wei Y, Tang Y, Zhang T, Tang X, Hu Y, Zhang J, Cui H, Wang J, Yao D, ... Luo C, et al. The effects of antipsychotics on interactions of dynamic functional connectivity in the triple-network in first episode schizophrenia. Schizophrenia Research. 236: 29-37. PMID 34365083 DOI: 10.1016/j.schres.2021.07.038  0.086
2016 Gu Y, Dong W, Luo C, Liu T. Efficient Reductive Decomposition of Perfluorooctane Sulfonate in a High Photon Flux UV/Sulfite System. Environmental Science & Technology. PMID 27607769 DOI: 10.1021/Acs.Est.6B03261  0.086
2012 Luo C, Guo ZW, Lai YX, Liao W, Liu Q, Kendrick KM, Yao DZ, Li H. Musical training induces functional plasticity in perceptual and motor networks: insights from resting-state FMRI. Plos One. 7: e36568. PMID 22586478 DOI: 10.1371/Journal.Pone.0036568  0.086
2019 Xia ZY, Luo C, Liu BW, Bian XQ, Li Y, Pang AM, Xu YH, Tan HM, Zhao YH. Shengui Sansheng Pulvis maintains blood-brain barrier integrity by vasoactive intestinal peptide after ischemic stroke. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 67: 153158. PMID 31999981 DOI: 10.1016/j.phymed.2019.153158  0.086
2023 Jiang H, Zu S, Lu Y, Sun Z, Adeerjiang A, Guo Q, Zhang H, Dong C, Wu Q, Ding H, Du D, Wang M, Liu C, Tang Y, Liang Z, ... Luo C, et al. A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region. Journal of Structural Biology. 107942. PMID 36781028 DOI: 10.1016/j.jsb.2023.107942  0.086
2020 Yao Y, He H, Duan M, Li S, Li C, Chen X, Yao G, Chang X, Shu H, Wang H, Luo C. The Effects of Music Intervention on Pallidum-DMN Circuit of Schizophrenia. Biomed Research International. 2020: 4107065. PMID 33015164 DOI: 10.1155/2020/4107065  0.086
2021 Qin Y, Zhang N, Chen Y, Tan Y, Yang Z, Shi Y, Luo C, Liu T, Yao D. Probing the Functional and Structural Connectivity Underlying EEG Traveling Waves. Brain Topography. PMID 34291338 DOI: 10.1007/s10548-021-00862-0  0.086
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2023 Yu J, Hu Y, Sheng M, Gao M, Guo W, Zhang Z, Wang D, Wu X, Li J, Chen Y, Zhao W, Liu C, Cui X, Chen X, Zhao C, ... ... Luo C, et al. Selective PPARγ modulator Diosmin improves insulin sensitivity and promotes browning of white fat. The Journal of Biological Chemistry. 103059. PMID 36841479 DOI: 10.1016/j.jbc.2023.103059  0.085
2017 He H, Yang M, Duan M, Chen X, Lai Y, Xia Y, Shao J, Biswal BB, Luo C, Yao D. Music Intervention Leads to Increased Insular Connectivity and Improved Clinical Symptoms in Schizophrenia. Frontiers in Neuroscience. 11: 744. PMID 29410607 DOI: 10.3389/Fnins.2017.00744  0.085
2010 Li S, Chen Q, Yu B, Xue K, Luo C, Xu Y, Gong Q, He C, Zhou D, He L, Yao D. Structural and functional changes mapped in the brains of amyotrophic lateral sclerosis patients with/without dysphagia: a pilot study. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 10: 280-7. PMID 19922114 DOI: 10.3109/17482960902893342  0.085
2016 Dong L, Wang P, Peng R, Jiang S, Klugah-Brown B, Luo C, Yao D. Altered basal ganglia-cortical functional connections in frontal lobe epilepsy: A resting-state fMRI study. Epilepsy Research. 128: 12-20. PMID 27792884 DOI: 10.1016/j.eplepsyres.2016.10.011  0.085
2022 Liu Y, Li H, Li W, Wang Y, Jiang J, Cao X, Zhang T, Tang Y, Wang J, Yao D, Luo C, Smith RC, Li C. Effects of transcranial direct current stimulation on brain changes and relation to cognition in patients with schizophrenia: a fMRI study. Brain Imaging and Behavior. PMID 35781191 DOI: 10.1007/s11682-022-00676-z  0.085
2014 Wu ZY, Zhang YB, Zhu KK, Luo C, Zhang JX, Cheng CR, Feng RH, Yang WZ, Zeng F, Wang Y, Xu PP, Guo JL, Liu X, Guan SH, Guo DA. Anti-inflammatory diterpenoids from the root bark of Acanthopanax gracilistylus. Journal of Natural Products. 77: 2342-51. PMID 25338180 DOI: 10.1021/np500125x  0.085
2015 Zheng XM, Meng FW, Geng F, Qi M, Luo C, Yang L, Wang ZT. Plantadeprate A, a Tricyclic Monoterpene Zwitterionic Guanidium, and Related Derivatives from the Seeds of Plantago depressa. Journal of Natural Products. PMID 26562611 DOI: 10.1021/acs.jnatprod.5b00368  0.084
2017 Luo C, Chen S, Xu N, Wang C, Sai WB, Zhao W, Li YC, Hu XJ, Tian H, Gao XD, Yao WB. Glycoengineering of pertuzumab and its impact on the pharmacokinetic/pharmacodynamic properties. Scientific Reports. 7: 46347. PMID 28397880 DOI: 10.1038/srep46347  0.084
2004 Luo C, Luo H, Zheng S, Gui C, Yue L, Yu C, Sun T, He P, Chen J, Shen J, Luo X, Li Y, Liu H, Bai D, Shen J, et al. Nucleocapsid protein of SARS coronavirus tightly binds to human cyclophilin A. Biochemical and Biophysical Research Communications. 321: 557-65. PMID 15358143 DOI: 10.1016/j.bbrc.2004.07.003  0.084
2014 Dong L, Gong D, Valdes-Sosa PA, Xia Y, Luo C, Xu P, Yao D. Simultaneous EEG-fMRI: trial level spatio-temporal fusion for hierarchically reliable information discovery. Neuroimage. 99: 28-41. PMID 24852457 DOI: 10.1016/j.neuroimage.2014.05.029  0.084
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2023 Zou Z, Wei J, Chen Y, Kang Y, Shi H, Yang F, Shi Z, Chen S, Zhou Y, Sepich-Poore C, Zhuang X, Zhou X, Jiang H, Wen Z, Jin P, ... Luo C, et al. FMRP phosphorylation modulates neuronal translation through YTHDF1. Molecular Cell. PMID 37949069 DOI: 10.1016/j.molcel.2023.10.028  0.084
2017 Chao C, Li F, Tan Z, Zhang W, Yang Y, Luo C. miR-195 inhibited abnormal activation of osteoblast differentiation in MC3T3-E1 cells via targeting RAF-1. Experimental Cell Research. PMID 29197556 DOI: 10.1016/j.yexcr.2017.11.030  0.084
2017 Sun Y, Xiao Q, Luo C, Zhao Y, Pu D, Zhao K, Chen J, Wang M, Liao Z. High-glucose induces tau hyperphosphorylation through activation of TLR9-P38MAPK pathway. Experimental Cell Research. PMID 28803064 DOI: 10.1016/j.yexcr.2017.07.032  0.084
2013 Liu X, Shen Q, Li J, Li S, Luo C, Zhu W, Luo X, Zheng M, Jiang H. In silico prediction of cytochrome P450-mediated site of metabolism (SOM). Protein and Peptide Letters. 20: 279-89. PMID 22591483 DOI: 10.2174/0929866511320030006  0.083
2010 Luo C, Yao Z, Li Q, Lei X, Zhou D, Qin Y, Xia Y, Lai Y, Gong Q, Yao D. Imaging foci of epileptic discharges from simultaneous EEG and fMRI using the canonical HRF. Epilepsy Research. 91: 133-42. PMID 20674274 DOI: 10.1016/j.eplepsyres.2010.07.003  0.083
2011 Urgard E, Vooder T, Võsa U, Välk K, Liu M, Luo C, Hoti F, Roosipuu R, Annilo T, Laine J, Frenz CM, Zhang L, Metspalu A. Metagenes associated with survival in non-small cell lung cancer. Cancer Informatics. 10: 175-83. PMID 21695068 DOI: 10.4137/Cin.S7135  0.083
2018 Hu X, Shen Y, Yang S, Lei W, Luo C, Hou Y, Bai G. Metabolite identification of ursolic acid in mouse plasma and urine after oral administration by ultra-high performance liquid chromatography/quadrupole time-of-flight mass spectrometry. Rsc Advances. 8: 6532-6539. PMID 35540410 DOI: 10.1039/c7ra11856b  0.083
2012 Wang YX, Luo C, Zhao D, Beck J, Nassal M. Extensive mutagenesis of the conserved box E motif in duck hepatitis B virus P protein reveals multiple functions in replication and a common structure with the primer grip in HIV-1 reverse transcriptase. Journal of Virology. 86: 6394-407. PMID 22514339 DOI: 10.1128/JVI.00011-12  0.083
2015 Duan M, Chen X, He H, Jiang Y, Jiang S, Xie Q, Lai Y, Luo C, Yao D. Altered Basal Ganglia Network Integration in Schizophrenia. Frontiers in Human Neuroscience. 9: 561. PMID 26528167 DOI: 10.3389/fnhum.2015.00561  0.083
2008 Yang X, Luo C, Cai J, Pierce WM, Tezel G. Phosphorylation-dependent interaction with 14-3-3 in the regulation of bad trafficking in retinal ganglion cells. Investigative Ophthalmology & Visual Science. 49: 2483-94. PMID 18296656 DOI: 10.1167/Iovs.07-1344  0.083
2020 Zhu Q, Jiang S, Luo C, Yang J, Yu L. Alterations of functional connectivity density in a Chinese family with a mild phenotype associated with a novel inherited variant of SCN8A. Epilepsy & Behavior : E&B. 112: 107379. PMID 32920374 DOI: 10.1016/j.yebeh.2020.107379  0.082
2018 Chen JL, Luo C, Pu D, Zhang GQ, Zhao YX, Sun Y, Zhao KX, Liao ZY, Lv AK, Zhu SY, Jing-Zhou, Xiao Q. Metformin attenuates diabetes-induced tau hyperphosphorylation in vitro and in vivo by enhancing autophagic clearance. Experimental Neurology. PMID 30219731 DOI: 10.1016/j.expneurol.2018.09.008  0.082
2022 Qi Q, Yan Y, Luo C, Fang C, Li Y, Cai X, Ling G, Song H, Zheng B. Bioinformatics Analysis Reveals Hub Genes That May Reduce Inflammation and Complications After Cardiopulmonary Bypass. The Heart Surgery Forum. 25: E243-E252. PMID 35486057 DOI: 10.1532/hsf.4487  0.082
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2017 Zhang L, Wang PE, Ying J, Jin X, Luo C, Xu T, Xu S, Dong R, Xiao L, Tong P, Jin H. Yougui Pills Attenuate Cartilage Degeneration via Activation of TGF-β/Smad Signaling in Chondrocyte of Osteoarthritic Mouse Model. Frontiers in Pharmacology. 8: 611. PMID 28928664 DOI: 10.3389/fphar.2017.00611  0.082
2022 Luo C, Lou DJ, Li YF, Yang L, Shao LJ, Liu JK, Yang XY. A new chamigrane sesquiterpene from the basidiomycete . Journal of Asian Natural Products Research. 1-6. PMID 35442135 DOI: 10.1080/10286020.2022.2064283  0.082
2018 Chen J, Jian X, Deng S, Ma Z, Shou X, Shen Y, Zhang Q, Song Z, Li Z, Peng H, Peng C, Chen M, Luo C, Zhao D, Ye Z, et al. Identification of recurrent USP48 and BRAF mutations in Cushing's disease. Nature Communications. 9: 3171. PMID 30093687 DOI: 10.1038/s41467-018-05275-5  0.082
2017 Zhou J, Wang D, Xi Y, Zhu X, Yang Y, Lv M, Luo C, Chen J, Ye X, Fang L, Xiao S. Assessing activity of Hepatitis A virus 3C protease using a cyclized luciferase-based biosensor. Biochemical and Biophysical Research Communications. PMID 28501618 DOI: 10.1016/j.bbrc.2017.05.063  0.082
2020 Jiang Y, Yao D, Zhou J, Tan Y, Huang H, Wang M, Chang X, Duan M, Luo C. Characteristics of disrupted topological organization in white matter functional connectome in schizophrenia. Psychological Medicine. 1-11. PMID 32880241 DOI: 10.1017/S0033291720003141  0.082
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2017 Gong D, Ma W, Gong J, He H, Dong L, Zhang D, Li J, Luo C, Yao D. Action Video Game Experience Related to Altered Large-Scale White Matter Networks. Neural Plasticity. 2017: 7543686. PMID 28706740 DOI: 10.1155/2017/7543686  0.081
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2021 Xu Y, Luo C, Wang J, Chen L, Chen J, Chen T, Zeng Q. Application of nanotechnology in the diagnosis and treatment of bladder cancer. Journal of Nanobiotechnology. 19: 393. PMID 34838048 DOI: 10.1186/s12951-021-01104-y  0.081
2014 Jin L, Ye F, Zhao D, Chen S, Zhu K, Zheng M, Jiang RW, Jiang H, Luo C. Metadynamics simulation study on the conformational transformation of HhaI methyltransferase: an induced-fit base-flipping hypothesis. Biomed Research International. 2014: 304563. PMID 25045662 DOI: 10.1155/2014/304563  0.081
2019 Zhang H, Luo C, Zhang G. LncRNA Regulates Epidermal Growth Factor Receptor and Autophagy to Promote Hepatocellular Carcinoma Metastasis by Interacting with . Dna and Cell Biology. PMID 31237446 DOI: 10.1089/dna.2019.4770  0.081
2020 Valdés-Sosa M, Ontivero-Ortega M, Iglesias-Fuster J, Lage-Castellanos A, Gong J, Luo C, Castro-Laguardia AM, Bobes MA, Marinazzo D, Yao D. Objects seen as scenes: Neural circuitry for attending whole or parts. Neuroimage. 116526. PMID 31935518 DOI: 10.1016/J.Neuroimage.2020.116526  0.081
2015 Wang P, Luo C, Dong L, Bin Y, Ma S, Yao D, Guo F, Yang Z. Altered intrinsic brain activity in patients with familial cortical myoclonic tremor and epilepsy: an amplitude of low-frequency fluctuation study. Journal of the Neurological Sciences. 351: 133-9. PMID 25796300 DOI: 10.1016/j.jns.2015.03.005  0.081
2023 Zhou J, Guo X, Liu X, Luo Y, Chang X, He H, Duan M, Li S, Li Q, Tan Y, Yao G, Yao D, Luo C. Intrinsic Therapeutic Link between Recuperative Cerebellar Con-Nectivity and Psychiatry Symptom in Schizophrenia Patients with Comorbidity of Metabolic Syndrome. Life (Basel, Switzerland). 13. PMID 36676092 DOI: 10.3390/life13010144  0.081
2014 Zhen Y, Qin G, Luo C, Jiang H, Yu K, Chen G. Exploring the RING-catalyzed ubiquitin transfer mechanism by MD and QM/MM calculations. Plos One. 9: e101663. PMID 25003393 DOI: 10.1371/journal.pone.0101663  0.08
2022 Yan FZ, Qian H, Liu F, Ding CH, Liu SQ, Xiao MC, Chen SJ, Zhang X, Luo C, Xie WF. Inhibition of protein arginine methyltransferase 1 alleviates liver fibrosis by attenuating the activation of hepatic stellate cells in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 36: e22489. PMID 35959865 DOI: 10.1096/fj.202200238R  0.08
2021 Li X, Liang Y, Lian C, Peng F, Xiao Y, He Y, Ma C, Wang Y, Zhang P, Deng Y, Su Y, Luo C, Kong X, Yang Q, Liu T, et al. CST6 protein and peptides inhibit breast cancer bone metastasis by suppressing CTSB activity and osteoclastogenesis. Theranostics. 11: 9821-9832. PMID 34815788 DOI: 10.7150/thno.62187  0.08
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2018 Pu D, Zhao Y, Chen J, Sun Y, Lv A, Zhu S, Luo C, Zhao K, Xiao Q. Protective effects of sulforaphane on cognitive impairments and AD-like lesions in diabetic mice are associated with the upregulation of Nrf2 transcription activity. Neuroscience. PMID 29684505 DOI: 10.1016/j.neuroscience.2018.04.017  0.08
2013 Liu W, Lu X, He G, Gao X, Li M, Wu J, Li Z, Wu J, Wang J, Luo C. Cytosolic protection against ultraviolet induced DNA damage by blueberry anthocyanins and anthocyanidins in hepatocarcinoma HepG2 cells. Biotechnology Letters. 35: 491-8. PMID 23192380 DOI: 10.1007/s10529-012-1105-2  0.08
2010 Liu X, Xie H, Luo C, Tong L, Wang Y, Peng T, Ding J, Jiang H, Li H. Discovery and SAR of thiazolidine-2,4-dione analogues as insulin-like growth factor-1 receptor (IGF-1R) inhibitors via hierarchical virtual screening. Journal of Medicinal Chemistry. 53: 2661-5. PMID 20178321 DOI: 10.1021/Jm901798E  0.08
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2024 Luo C, Li X, Li Y. Application of the Peroxidase‒like Activity of Nanomaterials for the Detection of Pathogenic Bacteria and Viruses. International Journal of Nanomedicine. 19: 441-452. PMID 38250191 DOI: 10.2147/IJN.S442335  0.08
2023 Luo F, Wang J, Zhang X, Jiang Y, Li Z, Luo C. In-vehicle network intrusion detection systems: a systematic survey of deep learning-based approaches. Peerj. Computer Science. 9: e1648. PMID 38077582 DOI: 10.7717/peerj-cs.1648  0.08
2006 Jin H, Zheng S, Wang Z, Luo C, Shen J, Jiang H, Zhang L, Zhang L. Structural insights into the effect of isonucleosides on B-DNA duplexes using molecular-dynamics simulations. Journal of Molecular Modeling. 12: 781-91. PMID 16450112 DOI: 10.1007/S00894-005-0085-8  0.08
2014 Guo W, Luo C, Wang C, Wang YH, Wang X, Gao XD, Yao WB. Suppression of human and mouse Th17 differentiation and autoimmunity by an endogenous Interleukin 23 receptor cytokine-binding homology region. The International Journal of Biochemistry & Cell Biology. 55: 304-10. PMID 25263529 DOI: 10.1016/j.biocel.2014.09.019  0.079
2012 Zhang H, Zhang CR, Zhu KK, Gao AH, Luo C, Li J, Yue JM. Fluevirosines A-C: a biogenesis inspired example in the discovery of new bioactive scaffolds from Flueggea virosa. Organic Letters. 15: 120-3. PMID 23244193 DOI: 10.1021/ol303146a  0.079
2018 Dong L, Luo C, Liu X, Jiang S, Li F, Feng H, Li J, Gong D, Yao D. Neuroscience Information Toolbox: An Open Source Toolbox for EEG-fMRI Multimodal Fusion Analysis. Frontiers in Neuroinformatics. 12: 56. PMID 30197593 DOI: 10.3389/fninf.2018.00056  0.079
2023 Li X, Li F, Ye F, Guo H, Chen W, Jin J, Wang Y, Dai P, Shi H, Tao H, Dang W, Ding Y, Wang M, Jiang H, Chen K, ... ... Luo C, et al. Spermine is a natural suppressor of AR signaling in castration-resistant prostate cancer. Cell Reports. 42: 112798. PMID 37453063 DOI: 10.1016/j.celrep.2023.112798  0.079
2016 Liu T, Lu D, Zhang H, Zheng M, Yang H, Xu Y, Luo C, Zhu W, Yu K, Jiang H. Applying high-performance computing in drug discovery and molecular simulation. National Science Review. 3: 49-63. PMID 32288960 DOI: 10.1093/nsr/nww003  0.079
2013 Luo C, Li Y, Yang L, Feng Z, Li Y, Long J, Liu J. A cigarette component acrolein induces accelerated senescence in human diploid fibroblast IMR-90 cells. Biogerontology. 14: 503-11. PMID 24026667 DOI: 10.1007/s10522-013-9454-3  0.079
2015 Guo W, Wang C, Wang X, Luo C, Yu D, Wang Y, Chen Y, Lei W, Gao X, Yao W. A novel human truncated IL12rβ1-Fc fusion protein ameliorates experimental autoimmune encephalomyelitis via specific binding of p40 to inhibit Th1 and Th17 cell differentiation. Oncotarget. PMID 26384304 DOI: 10.18632/oncotarget.5164  0.079
2021 Xiao MC, Qian H, Huang CK, Zheng BN, Yan FZ, Liu F, Zhang X, Chen SJ, Luo C, Xie WF. Imatinib inhibits the malignancy of hepatocellular carcinoma by suppressing autophagy. European Journal of Pharmacology. 174217. PMID 34087223 DOI: 10.1016/j.ejphar.2021.174217  0.079
2012 Ou-Yang SS, Lu JY, Kong XQ, Liang ZJ, Luo C, Jiang H. Computational drug discovery. Acta Pharmacologica Sinica. 33: 1131-40. PMID 22922346 DOI: 10.1038/aps.2012.109  0.079
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