Raju S Kucherlapati - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 
Area:
genetics
Website:
https://xconomy.com/author/rkucherlapati/

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Year Citation  Score
2019 Zhang Y, Yang L, Kucherlapati M, Hadjipanayis A, Pantazi A, Bristow CA, Lee EA, Mahadeshwar HS, Tang J, Zhang J, Seth S, Lee S, Ren X, Song X, Sun H, ... ... Kucherlapati R, et al. Global impact of somatic structural variation on the DNA methylome of human cancers. Genome Biology. 20: 209. PMID 31610796 DOI: 10.1186/S13059-019-1818-9  0.392
2018 Zhang Y, Yang L, Kucherlapati M, Chen F, Hadjipanayis A, Pantazi A, Bristow CA, Lee EA, Mahadeshwar HS, Tang J, Zhang J, Seth S, Lee S, Ren X, Song X, ... ... Kucherlapati R, et al. A Pan-Cancer Compendium of Genes Deregulated by Somatic Genomic Rearrangement across More Than 1,400 Cases. Cell Reports. 24: 515-527. PMID 29996110 DOI: 10.1016/J.Celrep.2018.06.025  0.378
2017 Jahid S, Sun J, Gelincik O, Blecua P, Edelmann W, Kucherlapati R, Zhou K, Jasin M, Gümüş ZH, Lipkin SM. Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair. Oncotarget. 8: 71574-71586. PMID 29069730 DOI: 10.18632/Oncotarget.17776  0.396
2017 Zhang Y, Kwok-Shing Ng P, Kucherlapati M, Chen F, Liu Y, Tsang YH, de Velasco G, Jeong KJ, Akbani R, Hadjipanayis A, Pantazi A, Bristow CA, Lee E, Mahadeshwar HS, Tang J, ... ... Kucherlapati R, et al. A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations. Cancer Cell. PMID 28528867 DOI: 10.1016/J.Ccell.2017.04.013  0.332
2017 Lu H, Villafane N, Dogruluk T, Grzeskowiak CL, Kong K, Tsang YH, Zagorodna O, Pantazi A, Yang L, Neill NJ, Kim YW, Creighton CJ, Verhaak RG, Mills GB, Park P, ... Kucherlapati RS, et al. Engineering and Functional Characterization of Fusion Genes Identifies Novel Oncogenic Drivers of Cancer. Cancer Research. PMID 28512244 DOI: 10.1158/0008-5472.Can-16-2745  0.366
2017 Cherniack AD, Shen H, Walter V, Stewart C, Murray BA, Bowlby R, Hu X, Ling S, Soslow RA, Broaddus RR, Zuna RE, Robertson G, Laird PW, Kucherlapati R, Mills GB, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 31: 411-423. PMID 28292439 DOI: 10.1016/J.Ccell.2017.02.010  0.351
2016 Sun Y, Ji P, Chen T, Zhou X, Yang D, Guo Y, Liu Y, Hu L, Xia D, Liu Y, Multani AS, Shmulevich I, Kucherlapati R, Kopetz S, Sood AK, et al. MIIP haploinsufficiency induces chromosomal instability and promotes tumour progression in colorectal cancer. The Journal of Pathology. PMID 27741356 DOI: 10.1002/Path.4823  0.38
2016 Yang L, Lee MS, Lu H, Oh DY, Kim YJ, Park D, Park G, Ren X, Bristow CA, Haseley PS, Lee S, Pantazi A, Kucherlapati R, Park WY, Scott KL, et al. Analyzing Somatic Genome Rearrangements in Human Cancers by Using Whole-Exome Sequencing. American Journal of Human Genetics. 98: 843-856. PMID 27153396 DOI: 10.1016/J.Ajhg.2016.03.017  0.399
2016 Chen F, Zhang Y, Şenbabaoğlu Y, Ciriello G, Yang L, Reznik E, Shuch B, Micevic G, De Velasco G, Shinbrot E, Noble MS, Lu Y, Covington KR, Xi L, Drummond JA, ... ... Kucherlapati R, et al. Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma. Cell Reports. PMID 26947078 DOI: 10.1016/J.Celrep.2016.02.024  0.329
2016 Weinstein JN, Lerner SP, Kwiatkowski DJ, Getz G, Kim J, Al-ahmadie HA, Cherniack AD, Guo G, Akbani R, Hoadley KA, Kim WY, Robertson G, Mungall AJ, Hinoue T, Laird PW, ... ... Kucherlapati R, et al. Abstract 128: Comprehensive molecular characterization of 412 muscle-invasive urothelial bladder carcinomas: final analysis of The Cancer Genome Atlas (TCGA) project Cancer Research. 76: 128-128. DOI: 10.1158/1538-7445.Am2016-128  0.356
2014 Davis CF, Ricketts CJ, Wang M, Yang L, Cherniack AD, Shen H, Buhay C, Kang H, Kim SC, Fahey CC, Hacker KE, Bhanot G, Gordenin DA, Chu A, Gunaratne PH, ... ... Kucherlapati R, et al. The somatic genomic landscape of chromophobe renal cell carcinoma. Cancer Cell. 26: 319-30. PMID 25155756 DOI: 10.1016/J.Ccr.2014.07.014  0.339
2014 Chen PC, Yin J, Yu HW, Yuan T, Fernandez M, Yung CK, Trinh QM, Peltekova VD, Reid JG, Tworog-Dube E, Morgan MB, Muzny DM, Stein L, McPherson JD, Roberts AE, ... ... Kucherlapati R, et al. Next-generation sequencing identifies rare variants associated with Noonan syndrome. Proceedings of the National Academy of Sciences of the United States of America. 111: 11473-8. PMID 25049390 DOI: 10.1073/Pnas.1324128111  0.335
2014 Weinstein JN, Kim J, Creighton CJ, Akbani R, Hoadley KA, Kim WY, Morgan MB, Hinoue T, Rosenberg JE, Bajorin DF, Hansel DE, Al-Ahmadie H, Gordenin D, Stuart JM, Robertson G, ... Kucherlapati R, et al. Comprehensive molecular profiling of urothelial bladder cancer at the DNA, RNA, and protein levels: A TCGA project. Journal of Clinical Oncology. 32: 4509-4509. DOI: 10.1200/Jco.2014.32.15_Suppl.4509  0.37
2014 Weinstein JN, Kim J, Creighton CJ, Akbani R, Hoadley KA, Kim WY, Morgan MB, Hinoue T, Cherniack A, Su X, Mungall AJ, Ryan MC, Rosenberg JE, Bajorin DF, Czerniak B, ... ... Kucherlapati R, et al. Abstract 987: Comprehensive characterization of urothelial bladder cancer: a TCGA Project update Cancer Research. 74: 987-987. DOI: 10.1158/1538-7445.Am2014-987  0.353
2014 Yang L, Luquette LJ, Gehlenborg N, Xi R, Haseley PS, Hsieh CH, Zhang C, Ren X, Protopopov A, Chin L, Kucherlapati R, Lee C, Park PJ. Erratum: Diverse mechanisms of somatic structural variations in human cancer genomes (Cell (2013) 153 (919-929)) Cell. 157. DOI: 10.1016/J.Cell.2014.05.020  0.316
2013 Kucherlapati R, Leinwand LA. Frank Ruddle (1929-2013). American Journal of Human Genetics. 92: 839-40. PMID 24242788 DOI: 10.1016/J.Ajhg.2013.05.012  0.565
2013 Brennan CW, Verhaak RG, McKenna A, Campos B, Noushmehr H, Salama SR, Zheng S, Chakravarty D, Sanborn JZ, Berman SH, Beroukhim R, Bernard B, Wu CJ, Genovese G, Shmulevich I, ... ... Kucherlapati R, et al. The somatic genomic landscape of glioblastoma. Cell. 155: 462-77. PMID 24120142 DOI: 10.1016/J.Cell.2013.09.034  0.334
2013 Kucherlapati R. Francis H. Ruddle (1929-2013): a pioneer in human gene mapping. Proceedings of the National Academy of Sciences of the United States of America. 110: 9619-20. PMID 23716665 DOI: 10.1073/Pnas.1308094110  0.399
2013 Yang L, Luquette LJ, Gehlenborg N, Xi R, Haseley PS, Hsieh CH, Zhang C, Ren X, Protopopov A, Chin L, Kucherlapati R, Lee C, Park PJ. Diverse mechanisms of somatic structural variations in human cancer genomes. Cell. 153: 919-29. PMID 23663786 DOI: 10.1016/J.Cell.2013.04.010  0.328
2013 Kandoth C, Schultz N, Cherniack AD, Akbani R, Liu Y, Shen H, Robertson AG, Pashtan I, Shen R, Benz CC, Yau C, Laird PW, Ding L, Zhang W, ... ... Kucherlapati R, et al. Integrated genomic characterization of endometrial carcinoma. Nature. 497: 67-73. PMID 23636398 DOI: 10.1038/Nature12113  0.308
2012 Kovalenko M, Dragileva E, St Claire J, Gillis T, Guide JR, New J, Dong H, Kucherlapati R, Kucherlapati MH, Ehrlich ME, Lee JM, Wheeler VC. Msh2 acts in medium-spiny striatal neurons as an enhancer of CAG instability and mutant huntingtin phenotypes in Huntington's disease knock-in mice. Plos One. 7: e44273. PMID 22970194 DOI: 10.1371/Journal.Pone.0044273  0.327
2012 Larman TC, DePalma SR, Hadjipanayis AG, Protopopov A, Zhang J, Gabriel SB, Chin L, Seidman CE, Kucherlapati R, Seidman JG. Spectrum of somatic mitochondrial mutations in five cancers. Proceedings of the National Academy of Sciences of the United States of America. 109: 14087-91. PMID 22891333 DOI: 10.1073/Pnas.1211502109  0.317
2012 Lee E, Iskow R, Yang L, Gokcumen O, Haseley P, Luquette LJ, Lohr JG, Harris CC, Ding L, Wilson RK, Wheeler DA, Gibbs RA, Kucherlapati R, Lee C, Kharchenko PV, et al. Landscape of somatic retrotransposition in human cancers. Science (New York, N.Y.). 337: 967-71. PMID 22745252 DOI: 10.1126/Science.1222077  0.363
2012 Kucherlapati R. Genetically modified mouse models for biomarker discovery and preclinical drug testing. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 625-30. PMID 22298895 DOI: 10.1158/1078-0432.Ccr-11-2021  0.375
2012 Lee E, Iskow R, Yang L, Gokcumen O, Haseley P, Luquette LJ, Lohr JG, Harris CC, Ding L, Wilson RK, Wheeler DA, Gibbs RA, Kucherlapati R, Lee C, Kharchenko PV, et al. Analysis of somatic retrotransposition in human cancers Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S6-O23  0.305
2012 Koboldt DC, Fulton RS, McLellan MD, Schmidt H, Kalicki-Veizer J, McMichael JF, Fulton LL, Dooling DJ, Ding L, Mardis ER, Wilson RK, Ally A, Balasundaram M, Butterfield YSN, Carlsen R, ... ... Kucherlapati R, et al. Comprehensive molecular portraits of human breast tumours Nature. 490: 61-70. DOI: 10.1038/Nature11412  0.311
2011 Hiramoto T, Kang G, Suzuki G, Satoh Y, Kucherlapati R, Watanabe Y, Hiroi N. Tbx1: identification of a 22q11.2 gene as a risk factor for autism spectrum disorder in a mouse model. Human Molecular Genetics. 20: 4775-85. PMID 21908517 DOI: 10.1093/Hmg/Ddr404  0.617
2010 Chen PC, Wakimoto H, Conner D, Araki T, Yuan T, Roberts A, Seidman C, Bronson R, Neel B, Seidman JG, Kucherlapati R. Activation of multiple signaling pathways causes developmental defects in mice with a Noonan syndrome–associated Sos1 mutation. The Journal of Clinical Investigation. 120: 4353-65. PMID 21041952 DOI: 10.1172/Jci43910  0.315
2010 Wang Y, Zhang W, Edelmann L, Kolodner RD, Kucherlapati R, Edelmann W. Cis lethal genetic interactions attenuate and alter p53 tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 5511-5. PMID 20212136 DOI: 10.1073/Pnas.1001223107  0.327
2010 Hung KE, Maricevich MA, Richard LG, Chen WY, Richardson MP, Kunin A, Bronson RT, Mahmood U, Kucherlapati R. Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment. Proceedings of the National Academy of Sciences of the United States of America. 107: 1565-70. PMID 20080688 DOI: 10.1073/Pnas.0908682107  0.326
2010 Kucherlapati MH, Lee K, Nguyen AA, Clark AB, Hou H, Rosulek A, Li H, Yang K, Fan K, Lipkin M, Bronson RT, Jelicks L, Kunkel TA, Kucherlapati R, Edelmann W. An Msh2 conditional knockout mouse for studying intestinal cancer and testing anticancer agents. Gastroenterology. 138: 993-1002.e1. PMID 19931261 DOI: 10.1053/J.Gastro.2009.11.009  0.356
2010 Baba Y, Shima K, Nosho K, Chung DC, Hung KE, Mahmood U, Kucherlapati R, Fuchs CS, Ogino S, Chan AT. S1935 Cathepsin B Expression and Survival After Diagnosis of Colorectal Cancer Gastroenterology. 138. DOI: 10.1016/S0016-5085(10)61306-6  0.346
2009 Itano O, Yang K, Fan K, Kurihara N, Shinozaki H, Abe S, Jin B, Gravaghi C, Edelmann W, Augenlicht L, Kopelovich L, Kucherlapati R, Lamprecht S, Lipkin M. Sulindac effects on inflammation and tumorigenesis in the intestine of mice with Apc and Mlh1 mutations. Carcinogenesis. 30: 1923-6. PMID 19755659 DOI: 10.1093/Carcin/Bgp200  0.326
2009 Suzuki G, Harper KM, Hiramoto T, Funke B, Lee M, Kang G, Buell M, Geyer MA, Kucherlapati R, Morrow B, Männistö PT, Agatsuma S, Hiroi N. Over-expression of a human chromosome 22q11.2 segment including TXNRD2, COMT and ARVCF developmentally affects incentive learning and working memory in mice. Human Molecular Genetics. 18: 3914-25. PMID 19617637 DOI: 10.1093/Hmg/Ddp334  0.594
2009 Herman DS, Hovingh GK, Iartchouk O, Rehm HL, Kucherlapati R, Seidman JG, Seidman CE. Filter-based hybridization capture of subgenomes enables resequencing and copy-number detection. Nature Methods. 6: 507-10. PMID 19543287 DOI: 10.1038/Nmeth.1343  0.322
2009 Kuraguchi M, Ohene-Baah NY, Sonkin D, Bronson RT, Kucherlapati R. Genetic mechanisms in Apc-mediated mammary tumorigenesis. Plos Genetics. 5: e1000367. PMID 19197353 DOI: 10.1371/Journal.Pgen.1000367  0.327
2009 Dragileva E, Hendricks A, Teed A, Gillis T, Lopez ET, Friedberg EC, Kucherlapati R, Edelmann W, Lunetta KL, MacDonald ME, Wheeler VC. Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes. Neurobiology of Disease. 33: 37-47. PMID 18930147 DOI: 10.1016/J.Nbd.2008.09.014  0.305
2009 Hiramoto T, Suzuki G, Kang G, Funke B, Watanabe Y, Kucherlapati R, Morrow B, Hiroi N. Tbx1 heterozygosity impairs working memory in mice Neuroscience Research. 65: S121-S122. DOI: 10.1016/J.Neures.2009.09.576  0.502
2008 Montgomery KT, Iartchouck O, Li L, Loomis S, Obourn V, Kucherlapati R. PolyPhred analysis software for mutation detection from fluorescence-based sequence data. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit 7.16. PMID 18972372 DOI: 10.1002/0471142905.Hg0716S59  0.31
2008 Kucherlapati MH, Yang K, Fan K, Kuraguchi M, Sonkin D, Rosulek A, Lipkin M, Bronson RT, Aronow BJ, Kucherlapati R. Loss of Rb1 in the gastrointestinal tract of Apc1638N mice promotes tumors of the cecum and proximal colon. Proceedings of the National Academy of Sciences of the United States of America. 105: 15493-8. PMID 18832169 DOI: 10.1073/Pnas.0802933105  0.327
2008 Chen PC, Kuraguchi M, Velasquez J, Wang Y, Yang K, Edwards R, Gillen D, Edelmann W, Kucherlapati R, Lipkin SM. Novel roles for MLH3 deficiency and TLE6-like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression. Plos Genetics. 4: e1000092. PMID 18551179 DOI: 10.1371/Journal.Pgen.1000092  0.351
2008 Barrera-Oro J, Liu TY, Gorden E, Kucherlapati R, Shao C, Tischfield JA. Role of the mismatch repair gene, Msh6, in suppressing genome instability and radiation-induced mutations. Mutation Research. 642: 74-9. PMID 18538799 DOI: 10.1016/J.Mrfmmm.2008.04.006  0.355
2008 Montgomery KT, Iartchouck O, Li L, Perera A, Yassin Y, Tamburino A, Loomis S, Kucherlapati R. Mutation detection using automated fluorescence-based sequencing. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit7.9. PMID 18428426 DOI: 10.1002/0471142905.Hg0709S57  0.309
2008 Busuttil RA, Lin Q, Stambrook PJ, Kucherlapati R, Vijg J. Mutation frequencies and spectra in DNA polymerase eta-deficient mice. Cancer Research. 68: 2081-4. PMID 18381412 DOI: 10.1158/0008-5472.Can-07-6274  0.352
2008 Avdievich E, Reiss C, Scherer SJ, Zhang Y, Maier SM, Jin B, Hou H, Rosenwald A, Riedmiller H, Kucherlapati R, Cohen PE, Edelmann W, Kneitz B. Distinct effects of the recurrent Mlh1G67R mutation on MMR functions, cancer, and meiosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 4247-52. PMID 18337503 DOI: 10.1073/Pnas.0800276105  0.368
2008 Swanson KD, Winter JM, Reis M, Bentires-Alj M, Greulich H, Grewal R, Hruban RH, Yeo CJ, Yassin Y, Iartchouk O, Montgomery K, Whitman SP, Caligiuri MA, Loh ML, Gilliland DG, ... ... Kucherlapati R, et al. SOS1 mutations are rare in human malignancies: implications for Noonan Syndrome patients. Genes, Chromosomes & Cancer. 47: 253-9. PMID 18064648 DOI: 10.1002/Gcc.20527  0.343
2007 Forrester S, Hung KE, Kuick R, Kucherlapati R, Haab BB. Low-volume, high-throughput sandwich immunoassays for profiling plasma proteins in mice: identification of early-stage systemic inflammation in a mouse model of intestinal cancer. Molecular Oncology. 1: 216-25. PMID 19305640 DOI: 10.1016/J.Molonc.2007.06.001  0.303
2007 Lencz T, Lambert C, DeRosse P, Burdick KE, Morgan TV, Kane JM, Kucherlapati R, Malhotra AK. Runs of homozygosity reveal highly penetrant recessive loci in schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 104: 19942-7. PMID 18077426 DOI: 10.1073/Pnas.0710021104  0.316
2007 Martin ES, Tonon G, Sinha R, Xiao Y, Feng B, Kimmelman AC, Protopopov A, Ivanova E, Brennan C, Montgomery K, Kucherlapati R, Bailey G, Redston M, Chin L, DePinho RA. Common and distinct genomic events in sporadic colorectal cancer and diverse cancer types. Cancer Research. 67: 10736-43. PMID 18006816 DOI: 10.1158/0008-5472.Can-07-2742  0.379
2007 Lencz T, Morgan TV, Athanasiou M, Dain B, Reed CR, Kane JM, Kucherlapati R, Malhotra AK. Converging evidence for a pseudoautosomal cytokine receptor gene locus in schizophrenia. Molecular Psychiatry. 12: 572-80. PMID 17522711 DOI: 10.1038/Sj.Mp.4001983  0.316
2007 Funke BH, Brown AC, Ramoni MF, Regan ME, Baglieri C, Finn CT, Babcock M, Shprintzen RJ, Morrow BE, Kucherlapati R. A novel, single nucleotide polymorphism-based assay to detect 22q11 deletions. Genetic Testing. 11: 91-100. PMID 17394398 DOI: 10.1089/Gte.2006.0507  0.351
2007 Roberts AE, Araki T, Swanson KD, Montgomery KT, Schiripo TA, Joshi VA, Li L, Yassin Y, Tamburino AM, Neel BG, Kucherlapati RS. Germline gain-of-function mutations in SOS1 cause Noonan syndrome. Nature Genetics. 39: 70-4. PMID 17143285 DOI: 10.1038/Ng1926  0.316
2007 Joshi VA, Roberts AE, Kucherlapati RS. Noonan syndrome associated congenital hypertrophic cardiomyopathy and the role of sarcomere gene mutations Progress in Pediatric Cardiology. 24: 75-76. DOI: 10.1016/J.Ppedcard.2007.08.009  0.338
2006 Dumstorf CA, Clark AB, Lin Q, Kissling GE, Yuan T, Kucherlapati R, McGregor WG, Kunkel TA. Participation of mouse DNA polymerase iota in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer. Proceedings of the National Academy of Sciences of the United States of America. 103: 18083-8. PMID 17114294 DOI: 10.1073/Pnas.0605247103  0.305
2006 Lee DG, Urbach JM, Wu G, Liberati NT, Feinbaum RL, Miyata S, Diggins LT, He J, Saucier M, Déziel E, Friedman L, Li L, Grills G, Montgomery K, Kucherlapati R, et al. Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial. Genome Biology. 7: R90. PMID 17038190 DOI: 10.1186/Gb-2006-7-10-R90  0.31
2006 Kuraguchi M, Wang XP, Bronson RT, Rothenberg R, Ohene-Baah NY, Lund JJ, Kucherlapati M, Maas RL, Kucherlapati R. Adenomatous polyposis coli (APC) is required for normal development of skin and thymus. Plos Genetics. 2: e146. PMID 17002498 DOI: 10.1371/Journal.Pgen.0020146  0.34
2006 Long JM, LaPorte P, Merscher S, Funke B, Saint-Jore B, Puech A, Kucherlapati R, Morrow BE, Skoultchi AI, Wynshaw-Boris A. Behavior of mice with mutations in the conserved region deleted in velocardiofacial/DiGeorge syndrome. Neurogenetics. 7: 247-57. PMID 16900388 DOI: 10.1007/S10048-006-0054-0  0.394
2006 Scherer SE, Muzny DM, Buhay CJ, Chen R, Cree A, Ding Y, Dugan-Rocha S, Gill R, Gunaratne P, Harris RA, Hawes AC, Hernandez J, Hodgson AV, Hume J, Jackson A, ... ... Kucherlapati R, et al. The finished DNA sequence of human chromosome 12. Nature. 440: 346-51. PMID 16541075 DOI: 10.1038/Nature04569  0.447
2006 Kates WR, Antshel KM, Abdulsabur N, Colgan D, Funke B, Fremont W, Higgins AM, Kucherlapati R, Shprintzen RJ. A gender-moderated effect of a functional COMT polymorphism on prefrontal brain morphology and function in velo-cardio-facial syndrome (22q11.2 deletion syndrome). American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 141: 274-80. PMID 16511839 DOI: 10.1002/Ajmg.B.30284  0.345
2006 Moran JL, Bolton AD, Tran PV, Brown A, Dwyer ND, Manning DK, Bjork BC, Li C, Montgomery K, Siepka SM, Vitaterna MH, Takahashi JS, Wiltshire T, Kwiatkowski DJ, Kucherlapati R, et al. Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse. Genome Research. 16: 436-40. PMID 16461637 DOI: 10.1101/Gr.4563306  0.356
2006 Burdick KE, Lencz T, Funke B, Finn CT, Szeszko PR, Kane JM, Kucherlapati R, Malhotra AK. Genetic variation in DTNBP1 influences general cognitive ability. Human Molecular Genetics. 15: 1563-8. PMID 16415041 DOI: 10.1093/Hmg/Ddi481  0.303
2006 Lin Q, Clark AB, McCulloch SD, Yuan T, Bronson RT, Kunkel TA, Kucherlapati R. Increased susceptibility to UV-induced skin carcinogenesis in polymerase eta-deficient mice. Cancer Research. 66: 87-94. PMID 16397220 DOI: 10.1158/0008-5472.Can-05-1862  0.306
2005 Hiroi N, Zhu H, Lee M, Funke B, Arai M, Itokawa M, Kucherlapati R, Morrow B, Sawamura T, Agatsuma S. A 200-kb region of human chromosome 22q11.2 confers antipsychotic-responsive behavioral abnormalities in mice. Proceedings of the National Academy of Sciences of the United States of America. 102: 19132-7. PMID 16365290 DOI: 10.1073/Pnas.0509635102  0.613
2005 Ziv S, Brenner O, Amariglio N, Smorodinsky NI, Galron R, Carrion DV, Zhang W, Sharma GG, Pandita RK, Agarwal M, Elkon R, Katzin N, Bar-Am I, Pandita TK, Kucherlapati R, et al. Impaired genomic stability and increased oxidative stress exacerbate different features of Ataxia-telangiectasia. Human Molecular Genetics. 14: 2929-43. PMID 16150740 DOI: 10.1093/Hmg/Ddi324  0.37
2005 Lai WR, Johnson MD, Kucherlapati R, Park PJ. Comparative analysis of algorithms for identifying amplifications and deletions in array CGH data. Bioinformatics (Oxford, England). 21: 3763-70. PMID 16081473 DOI: 10.1093/Bioinformatics/Bti611  0.338
2005 Wang Y, Putnam CD, Kane MF, Zhang W, Edelmann L, Russell R, Carrión DV, Chin L, Kucherlapati R, Kolodner RD, Edelmann W. Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in mice. Nature Genetics. 37: 750-5. PMID 15965476 DOI: 10.1038/Ng1587  0.419
2005 Yang K, Fan KH, Lamprecht SA, Edelmann W, Kopelovich L, Kucherlapati R, Lipkin M. Peroxisome proliferator-activated receptor gamma agonist troglitazone induces colon tumors in normal C57BL/6J mice and enhances colonic carcinogenesis in Apc1638 N/+ Mlh1+/- double mutant mice. International Journal of Cancer. Journal International Du Cancer. 116: 495-9. PMID 15818612 DOI: 10.1002/Ijc.21018  0.312
2005 Roberts AE, Hult B, Rehm HL, Rehm HL, McDonough B, Barr S, Seidman CE, Seidman JG, Kucherlapati RS. The PTPN11 gene is not implicated in nonsyndromic hypertrophic cardiomyopathy. American Journal of Medical Genetics. Part A. 132: 333-4. PMID 15578621 DOI: 10.1002/Ajmg.A.30405  0.346
2004 Shao C, Deng L, Chen Y, Kucherlapati R, Stambrook PJ, Tischfield JA. Mlh1 mediates tissue-specific regulation of mitotic recombination. Oncogene. 23: 9017-24. PMID 15480418 DOI: 10.1038/Sj.Onc.1208148  0.357
2004 Yang G, Scherer SJ, Shell SS, Yang K, Kim M, Lipkin M, Kucherlapati R, Kolodner RD, Edelmann W. Dominant effects of an Msh6 missense mutation on DNA repair and cancer susceptibility. Cancer Cell. 6: 139-50. PMID 15324697 DOI: 10.1016/J.Ccr.2004.06.024  0.31
2004 Lin DP, Wang Y, Scherer SJ, Clark AB, Yang K, Avdievich E, Jin B, Werling U, Parris T, Kurihara N, Umar A, Kucherlapati R, Lipkin M, Kunkel TA, Edelmann W. An Msh2 point mutation uncouples DNA mismatch repair and apoptosis. Cancer Research. 64: 517-22. PMID 14744764 DOI: 10.1158/0008-5472.Can-03-2957  0.336
2003 Kabbarah O, Mallon MA, Pfeifer JD, Edelmann W, Kucherlapati R, Goodfellow PJ. A panel of repeat markers for detection of microsatellite instability in murine tumors. Molecular Carcinogenesis. 38: 155-9. PMID 14639654 DOI: 10.1002/Mc.10157  0.348
2003 Pretlow TP, Edelmann W, Kucherlapati R, Pretlow TG, Augenlicht LH. Spontaneous aberrant crypt foci in Apc1638N mice with a mutant Apc allele. The American Journal of Pathology. 163: 1757-63. PMID 14578176 DOI: 10.1016/S0002-9440(10)63535-3  0.35
2003 Supavekin S, Zhang W, Kucherlapati R, Kaskel FJ, Moore LC, Devarajan P. Differential gene expression following early renal ischemia/reperfusion. Kidney International. 63: 1714-24. PMID 12675847 DOI: 10.1046/J.1523-1755.2003.00928.X  0.305
2002 Waterston RH, Lindblad-Toh K, Birney E, Rogers J, Abril JF, Agarwal P, Agarwala R, Ainscough R, Alexandersson M, An P, Antonarakis SE, Attwood J, Baertsch R, Bailey J, ... ... Kucherlapati RS, et al. Initial sequencing and comparative analysis of the mouse genome. Nature. 420: 520-62. PMID 12466850 DOI: 10.1038/Nature01262  0.305
2002 Kochilas L, Merscher-Gomez S, Lu MM, Potluri V, Liao J, Kucherlapati R, Morrow B, Epstein JA. The role of neural crest during cardiac development in a mouse model of DiGeorge syndrome. Developmental Biology. 251: 157-66. PMID 12413905 DOI: 10.1006/Dbio.2002.0819  0.359
2002 Kucherlapati M, Yang K, Kuraguchi M, Zhao J, Lia M, Heyer J, Kane MF, Fan K, Russell R, Brown AM, Kneitz B, Edelmann W, Kolodner RD, Lipkin M, Kucherlapati R. Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 99: 9924-9. PMID 12119409 DOI: 10.1073/Pnas.152321699  0.394
2002 Wei K, Kucherlapati R, Edelmann W. Mouse models for human DNA mismatch-repair gene defects. Trends in Molecular Medicine. 8: 346-53. PMID 12114115 DOI: 10.1016/S1471-4914(02)02359-6  0.402
2002 Desai KV, Xiao N, Wang W, Gangi L, Greene J, Powell JI, Dickson R, Furth P, Hunter K, Kucherlapati R, Simon R, Liu ET, Green JE. Initiating oncogenic event determines gene-expression patterns of human breast cancer models. Proceedings of the National Academy of Sciences of the United States of America. 99: 6967-72. PMID 12011455 DOI: 10.1073/Pnas.102172399  0.355
2002 Tartaglia M, Kalidas K, Shaw A, Song X, Musat DL, van der Burgt I, Brunner HG, Bertola DR, Crosby A, Ion A, Kucherlapati RS, Jeffery S, Patton MA, Gelb BD. PTPN11 mutations in Noonan syndrome: molecular spectrum, genotype-phenotype correlation, and phenotypic heterogeneity. American Journal of Human Genetics. 70: 1555-63. PMID 11992261 DOI: 10.1086/340847  0.316
2002 Wang H, Douglas W, Lia M, Edelmann W, Kucherlapati R, Podsypanina K, Parsons R, Ellenson LH. DNA mismatch repair deficiency accelerates endometrial tumorigenesis in Pten heterozygous mice. The American Journal of Pathology. 160: 1481-6. PMID 11943731 DOI: 10.1016/S0002-9440(10)62573-4  0.303
2001 Tartaglia M, Mehler EL, Goldberg R, Zampino G, Brunner HG, Kremer H, van der Burgt I, Crosby AH, Ion A, Jeffery S, Kalidas K, Patton MA, Kucherlapati RS, Gelb BD. Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome. Nature Genetics. 29: 465-8. PMID 11704759 DOI: 10.1038/Ng772  0.354
2001 Kucherlapati R, DePinho RA. Cancer. Telomerase meets its mismatch. Nature. 411: 647-8. PMID 11395749 DOI: 10.1038/35079715  0.346
2001 Merscher S, Funke B, Epstein JA, Heyer J, Puech A, Lu MM, Xavier RJ, Demay MB, Russell RG, Factor S, Tokooya K, Jore BS, Lopez M, Pandita RK, Lia M, ... ... Kucherlapati R, et al. TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome. Cell. 104: 619-29. PMID 11239417 DOI: 10.1016/S0092-8674(01)00247-1  0.401
2001 Montgomery KT, Lee E, Miller A, Lau S, Shim C, Decker J, Chiu D, Emerling S, Sekhon M, Kim R, Lenz J, Han J, Ioshikhes I, Renault B, Marondel I, ... ... Kucherlapati R, et al. A high-resolution map of human chromosome 12. Nature. 409: 945-6. PMID 11237017 DOI: 10.1038/35057174  0.358
2001 Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, Devon K, Dewar K, Doyle M, FitzHugh W, Funke R, Gage D, Harris K, Heaford A, Howland J, ... ... Kucherlapati RS, et al. Initial sequencing and analysis of the human genome. Nature. 409: 860-921. PMID 11237011 DOI: 10.1038/35057062  0.306
2001 Tartaglia M, Mehler E, Goldberg R, Zampino G, Brunner H, Kremer H, van der Burgt I, Crosby A, Ion A, Jeffery S, Kalidas K, Patton M, Kucherlapati R, Gelb B. Correction: Mutations in the protein tyrosine kinase gene, PTPN11, cause Noonan syndrome Nature Genetics. 29: 491-491. DOI: 10.1038/Ng1201-491C  0.313
2001 Bourdon V, Mhlanga MM, Massimi A, Tyagi S, Kucherlapati R, Chaganti RS. A 12p array to identify amplified and overexpressed sequences in testicular germ cell tumors Nature Genetics. 27: 44-44. DOI: 10.1038/87016  0.339
2000 Ion A, Crosby AH, Kremer H, Kenmochi N, Van Reen M, Fenske C, Van Der Burgt I, Brunner HG, Montgomery K, Kucherlapati RS, Patton MA, Page C, Mariman E, Jeffery S. Detailed mapping, mutation analysis, and intragenic polymorphism identification in candidate Noonan syndrome genes MYL2, DCN, EPS8, and RPL6. Journal of Medical Genetics. 37: 884-6. PMID 11185075 DOI: 10.1136/Jmg.37.11.884  0.436
2000 Kuraguchi M, Edelmann W, Yang K, Lipkin M, Kucherlapati R, Brown AM. Tumor-associated Apc mutations in Mlh1-/- Apc1638N mice reveal a mutational signature of Mlh1 deficiency. Oncogene. 19: 5755-63. PMID 11126362 DOI: 10.1038/Sj.Onc.1203962  0.316
2000 Lee SG, Cho KA, Choi YH, Montgomery K, Lee E, Miller A, Kucherlapati R, Song K. A sequence-ready map for human chromosome 12q15-21. Dna Sequence : the Journal of Dna Sequencing and Mapping. 11: 353-61. PMID 11092752 DOI: 10.3109/10425170009033255  0.372
2000 Lee H, Choi E, Seomun Y, Montgomery K, Huebner A, Lee E, Lau S, Joo CK, Kucherlapati R, Yoon SJ. High-resolution transcript map of the region spanning D12S1629 and D12S312 at chromosome 12q13: triple A syndrome-linked region. Genome Research. 10: 1561-7. PMID 11042153 DOI: 10.1101/Gr.142100  0.43
2000 Smits R, Hofland N, Edelmann W, Geugien M, Jagmohan-Changur S, Albuquerque C, Breukel C, Kucherlapati R, Kielman MF, Fodde R. Somatic Apc mutations are selected upon their capacity to inactivate the beta-catenin downregulating activity. Genes, Chromosomes & Cancer. 29: 229-39. PMID 10992298 DOI: 10.1002/1098-2264(2000)9999:9999<::Aid-Gcc1033>3.0.Co;2-R  0.315
2000 Casey M, Vaughan CJ, He J, Hatcher CJ, Winter JM, Weremowicz S, Montgomery K, Kucherlapati R, Morton CC, Basson CT. Mutations in the protein kinase A R1alpha regulatory subunit cause familial cardiac myxomas and Carney complex. The Journal of Clinical Investigation. 106: R31-8. PMID 10974026 DOI: 10.1172/Jci10841  0.395
2000 Peyron C, Faraco J, Rogers W, Ripley B, Overeem S, Charnay Y, Nevsimalova S, Aldrich M, Reynolds D, Albin R, Li R, Hungs M, Pedrazzoli M, Padigaru M, Kucherlapati M, ... ... Kucherlapati R, et al. A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nature Medicine. 6: 991-7. PMID 10973318 DOI: 10.1038/79690  0.315
2000 Puech A, Saint-Jore B, Merscher S, Russell RG, Cherif D, Sirotkin H, Xu H, Factor S, Kucherlapati R, Skoultchi AI. Normal cardiovascular development in mice deficient for 16 genes in 550 kb of the velocardiofacial/DiGeorge syndrome region. Proceedings of the National Academy of Sciences of the United States of America. 97: 10090-5. PMID 10963672 DOI: 10.1073/Pnas.97.18.10090  0.748
2000 Bala S, Oliver H, Renault B, Montgomery K, Dutta S, Rao P, Houldsworth J, Kucherlapati R, Wang X, Chaganti RS, Murty VV. Genetic analysis of the APAF1 gene in male germ cell tumors. Genes, Chromosomes & Cancer. 28: 258-68. PMID 10862031 DOI: 10.1002/1098-2264(200007)28:3<258::Aid-Gcc3>3.0.Co;2-R  0.474
2000 Kneitz B, Cohen PE, Avdievich E, Zhu L, Kane MF, Hou H, Kolodner RD, Kucherlapati R, Pollard JW, Edelmann W. MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice. Genes & Development. 14: 1085-97. PMID 10809667 DOI: 10.1101/Gad.14.9.1085  0.39
2000 Pellegata NS, Dieguez-Lucena JL, Joensuu T, Lau S, Montgomery KT, Krahe R, Kivelä T, Kucherlapati R, Forsius H, de la Chapelle A. Mutations in KERA, encoding keratocan, cause cornea plana. Nature Genetics. 25: 91-5. PMID 10802664 DOI: 10.1038/75664  0.367
2000 Renedo M, Arce I, Montgomery K, Roda-Navarro P, Lee E, Kucherlapati R, Fernández-Ruiz E. A sequence-ready physical map of the region containing the human natural killer gene complex on chromosome 12p12.3-p13.2. Genomics. 65: 129-36. PMID 10783260 DOI: 10.1006/Geno.2000.6163  0.421
2000 Roda-Navarro P, Arce I, Renedo M, Montgomery K, Kucherlapati R, Fernández-Ruiz E. Human KLRF1, a novel member of the killer cell lectin-like receptor gene family: molecular characterization, genomic structure, physical mapping to the NK gene complex and expression analysis. European Journal of Immunology. 30: 568-76. PMID 10671213 DOI: 10.1002/1521-4141(200002)30:2<568::Aid-Immu568>3.0.Co;2-Y  0.402
2000 Wu G, Markowitz GS, Li L, D'Agati VD, Factor SM, Geng L, Tibara S, Tuchman J, Cai Y, Park JH, van Adelsberg J, Hou H, Kucherlapati R, Edelmann W, Somlo S. Cardiac defects and renal failure in mice with targeted mutations in Pkd2. Nature Genetics. 24: 75-8. PMID 10615132 DOI: 10.1038/71724  0.312
1999 Heyer J, Escalante-Alcalde D, Lia M, Boettinger E, Edelmann W, Stewart CL, Kucherlapati R. Postgastrulation Smad2-deficient embryos show defects in embryo turning and anterior morphogenesis. Proceedings of the National Academy of Sciences of the United States of America. 96: 12595-600. PMID 10535967 DOI: 10.1073/Pnas.96.22.12595  0.305
1999 Heyer J, Yang K, Lipkin M, Edelmann W, Kucherlapati R. Mouse models for colorectal cancer. Oncogene. 18: 5325-33. PMID 10498885 DOI: 10.1038/Sj.Onc.1203036  0.378
1999 Murty VV, Montgomery K, Dutta S, Bala S, Renault B, Bosl GJ, Kucherlapati R, Chaganti RS. A 3-Mb high-resolution BAC/PAC contig of 12q22 encompassing the 830-kb consensus minimal deletion in male germ cell tumors. Genome Research. 9: 662-71. PMID 10413405 DOI: 10.1101/Gr.9.7.662  0.408
1999 Smits R, Kielman MF, Breukel C, Zurcher C, Neufeld K, Jagmohan-Changur S, Hofland N, van Dijk J, White R, Edelmann W, Kucherlapati R, Khan PM, Fodde R. Apc1638T: a mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development. Genes & Development. 13: 1309-21. PMID 10346819 DOI: 10.1101/Gad.13.10.1309  0.332
1999 Sakuntabhai A, Ruiz-Perez V, Carter S, Jacobsen N, Burge S, Monk S, Smith M, Munro CS, O'Donovan M, Craddock N, Kucherlapati R, Rees JL, Owen M, Lathrop GM, Monaco AP, et al. Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease. Nature Genetics. 21: 271-7. PMID 10080178 DOI: 10.1038/6784  0.389
1999 Weiss A, McDonough D, Wertman B, Acakpo-Satchivi L, Montgomery K, Kucherlapati R, Leinwand L, Krauter K. Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved. Proceedings of the National Academy of Sciences of the United States of America. 96: 2958-63. PMID 10077619 DOI: 10.1073/Pnas.96.6.2958  0.586
1999 Edelmann W, Cohen PE, Kneitz B, Winand N, Lia M, Heyer J, Kolodner R, Pollard JW, Kucherlapati R. Mammalian MutS homologue 5 is required for chromosome pairing in meiosis. Nature Genetics. 21: 123-7. PMID 9916805 DOI: 10.1038/5075  0.397
1998 Saint-Jore B, Puech A, Heyer J, Lin Q, Raine C, Kucherlapati R, Skoultchi AI. Goosecoid-like (Gscl), a candidate gene for velocardiofacial syndrome, is not essential for normal mouse development. Human Molecular Genetics. 7: 1841-9. PMID 9811927 DOI: 10.1093/Hmg/7.12.1841  0.424
1998 Ness SL, Edelmann W, Jenkins TD, Liedtke W, Rustgi AK, Kucherlapati R. Mouse keratin 4 is necessary for internal epithelial integrity. The Journal of Biological Chemistry. 273: 23904-11. PMID 9727004 DOI: 10.1074/Jbc.273.37.23904  0.327
1998 Kucherlapati R. Gene knockouts galore. Nature Biotechnology. 16: 519-20. PMID 9624678 DOI: 10.1038/Nbt0698-519  0.347
1998 Wu G, D'Agati V, Cai Y, Markowitz G, Park JH, Reynolds DM, Maeda Y, Le TC, Hou H, Kucherlapati R, Edelmann W, Somlo S. Somatic inactivation of Pkd2 results in polycystic kidney disease. Cell. 93: 177-88. PMID 9568711 DOI: 10.1016/S0092-8674(00)81570-6  0.312
1997 Funke B, Saint-Jore B, Puech A, Sirotkin H, Edelmann L, Carlson C, Raft S, Pandita RK, Kucherlapati R, Skoultchi A, Morrow BE. Characterization and mutation analysis of goosecoid-like (GSCL), a homeodomain-containing gene that maps to the critical region for VCFS/DGS on 22q11. Genomics. 46: 364-72. PMID 9441739 DOI: 10.1006/Geno.1997.5046  0.737
1997 Puech A, Saint-Jore B, Funke B, Gilbert DJ, Sirotkin H, Copeland NG, Jenkins NA, Kucherlapati R, Morrow B, Skoultchi AI. Comparative mapping of the human 22q11 chromosomal region and the orthologous region in mice reveals complex changes in gene organization. Proceedings of the National Academy of Sciences of the United States of America. 94: 14608-13. PMID 9405660 DOI: 10.1073/Pnas.94.26.14608  0.752
1997 Merscher S, Marondel I, Pedeutour F, Gaudray P, Kucherlapati R, Turc-Carel C. Identification of new translocation breakpoints at 12q13 in lipomas. Genomics. 46: 70-7. PMID 9403060 DOI: 10.1006/Geno.1997.4993  0.431
1997 Edelmann W, Yang K, Umar A, Heyer J, Lau K, Fan K, Liedtke W, Cohen PE, Kane MF, Lipford JR, Yu N, Crouse GF, Pollard JW, Kunkel T, Lipkin M, ... ... Kucherlapati R, et al. Mutation in the mismatch repair gene Msh6 causes cancer susceptibility. Cell. 91: 467-77. PMID 9390556 DOI: 10.1016/S0092-8674(00)80433-X  0.384
1997 Acakpo-Satchivi LJ, Edelmann W, Sartorius C, Lu BD, Wahr PA, Watkins SC, Metzger JM, Leinwand L, Kucherlapati R. Growth and muscle defects in mice lacking adult myosin heavy chain genes. The Journal of Cell Biology. 139: 1219-29. PMID 9382868 DOI: 10.1083/Jcb.139.5.1219  0.502
1997 Renault B, Hovnanian A, Bryce S, Chang JJ, Lau S, Sakuntabhai A, Monk S, Carter S, Ross CJ, Pang J, Twells R, Chamberlain S, Monaco AP, Strachan T, Kucherlapati R. A sequence-ready physical map of a region of 12q24.1. Genomics. 45: 271-8. PMID 9344649 DOI: 10.1006/Geno.1997.4888  0.411
1997 Carlson C, Sirotkin H, Pandita R, Goldberg R, McKie J, Wadey R, Patanjali SR, Weissman SM, Anyane-Yeboa K, Warburton D, Scambler P, Shprintzen R, Kucherlapati R, Morrow BE. Molecular definition of 22q11 deletions in 151 velo-cardio-facial syndrome patients. American Journal of Human Genetics. 61: 620-9. PMID 9326327 DOI: 10.1086/515508  0.739
1997 Sirotkin H, Morrow B, Saint-Jore B, Puech A, Das Gupta R, Patanjali SR, Skoultchi A, Weissman SM, Kucherlapati R. Identification, characterization, and precise mapping of a human gene encoding a novel membrane-spanning protein from the 22q11 region deleted in velo-cardio-facial syndrome. Genomics. 42: 245-51. PMID 9192844 DOI: 10.1006/Geno.1997.4734  0.731
1997 Marcus DM, Rustgi AK, Defoe D, Brooks SE, McCormick RS, Thompson TP, Edelmann W, Kucherlapati R, Smith S. Retinal pigment epithelium abnormalities in mice with adenomatous polyposis coli gene disruption. Archives of Ophthalmology (Chicago, Ill. : 1960). 115: 645-50. PMID 9152133 DOI: 10.1001/Archopht.1997.01100150647013  0.334
1997 Sirotkin H, O'Donnell H, DasGupta R, Halford S, St Jore B, Puech A, Parimoo S, Morrow B, Skoultchi A, Weissman SM, Scambler P, Kucherlapati R. Identification of a new human catenin gene family member (ARVCF) from the region deleted in velo-cardio-facial syndrome. Genomics. 41: 75-83. PMID 9126485 DOI: 10.1006/Geno.1997.4627  0.722
1997 Yang K, Edelmann W, Fan K, Lau K, Kolli VR, Fodde R, Khan PM, Kucherlapati R, Lipkin M. A mouse model of human familial adenomatous polyposis. The Journal of Experimental Zoology. 277: 245-54. PMID 9062998 DOI: 10.1002/(Sici)1097-010X(19970215)277:3<245::Aid-Jez5>3.0.Co;2-O  0.344
1997 Smits R, Kartheuser A, Jagmohan-Changur S, Leblanc V, Breukel C, de Vries A, van Kranen H, van Krieken JH, Williamson S, Edelmann W, Kucherlapati R, KhanPM, Fodde R. Loss of Apc and the entire chromosome 18 but absence of mutations at the Ras and Tp53 genes in intestinal tumors from Apc1638N, a mouse model for Apc-driven carcinogenesis. Carcinogenesis. 18: 321-7. PMID 9054624 DOI: 10.1093/Carcin/18.2.321  0.396
1997 Hamann J, Montgomery KT, Lau S, Kucherlapati R, van Lier RA. AICL: a new activation-induced antigen encoded by the human NK gene complex. Immunogenetics. 45: 295-300. PMID 9038101 DOI: 10.1007/S002510050208  0.374
1997 Basson CT, Bachinsky DR, Lin RC, Levi T, Elkins JA, Soults J, Grayzel D, Kroumpouzou E, Traill TA, Leblanc-Straceski J, Renault B, Kucherlapati R, Seidman JG, Seidman CE. Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome. Nature Genetics. 15: 30-5. PMID 8988165 DOI: 10.1038/Ng0197-30  0.372
1996 Lipkin M, Yang K, Edelmann W, Newmark H, Fan KH, Risio M, Kucherlapati R. Inherited and acquired risk factors in colonic neoplasia and modulation by chemopreventive interventions. Journal of Cellular Biochemistry. Supplement. 25: 136-41. PMID 9027610 DOI: 10.1002/(Sici)1097-4644(1996)25+<136::Aid-Jcb19>3.0.Co;2-M  0.312
1996 Cupelli L, Renault B, Leblanc-Straceski J, Banks A, Ward D, Kucherlapati RS, Krauter K. Assignment of the human myogenic factors 5 and 6 (MYF5, MYF6) gene cluster to 12q21 by in situ hybridization and physical mapping of the locus between D12S350 and D12S106. Cytogenetics and Cell Genetics. 72: 250-1. PMID 8978788 DOI: 10.1159/000134201  0.399
1996 Deere M, Johnson J, Garza S, Harrison WR, Yoon SJ, Elder FF, Kucherlapati R, Hook M, Hecht JT. Characterization of human DSPG3, a small dermatan sulfate proteoglycan. Genomics. 38: 399-404. PMID 8975717 DOI: 10.1006/Geno.1996.0643  0.38
1996 Marondel I, Renault B, Lieman J, Ward D, Kucherlapati R. Physical mapping of the human neurotensin gene (NTS) between markers D12S1444 and D12S81 on chromosome 12q21. Genomics. 38: 243-5. PMID 8954810 DOI: 10.1006/Geno.1996.0624  0.448
1996 Barnes KC, Neely JD, Duffy DL, Freidhoff LR, Breazeale DR, Schou C, Naidu RP, Levett PN, Renault B, Kucherlapati R, Iozzino S, Ehrlich E, Beaty TH, Marsh DG. Linkage of asthma and total serum IgE concentration to markers on chromosome 12q: evidence from Afro-Caribbean and Caucasian populations. Genomics. 37: 41-50. PMID 8921368 DOI: 10.1006/Geno.1996.0518  0.329
1996 Schoenberg Fejzo M, Ashar HR, Krauter KS, Powell WL, Rein MS, Weremowicz S, Yoon SJ, Kucherlapati RS, Chada K, Morton CC. Translocation breakpoints upstream of the HMGIC gene in uterine leiomyomata suggest dysregulation of this gene by a mechanism different from that in lipomas. Genes, Chromosomes & Cancer. 17: 1-6. PMID 8889500 DOI: 10.1002/(Sici)1098-2264(199609)17:1<1::Aid-Gcc1>3.0.Co;2-0  0.431
1996 Lachman HM, Morrow B, Shprintzen R, Veit S, Parsia SS, Faedda G, Goldberg R, Kucherlapati R, Papolos DF. Association of codon 108/158 catechol-O-methyltransferase gene polymorphism with the psychiatric manifestations of velo-cardio-facial syndrome. American Journal of Medical Genetics. 67: 468-72. PMID 8886163 DOI: 10.1002/(Sici)1096-8628(19960920)67:5<468::Aid-Ajmg5>3.0.Co;2-G  0.357
1996 Murty VV, Renault B, Falk CT, Bosl GJ, Kucherlapati R, Chaganti RS. Physical mapping of a commonly deleted region, the site of a candidate tumor suppressor gene, at 12q22 in human male germ cell tumors. Genomics. 35: 562-70. PMID 8812492 DOI: 10.1006/Geno.1996.0398  0.391
1996 Sirotkin H, Morrow B, DasGupta R, Goldberg R, Patanjali SR, Shi G, Cannizzaro L, Shprintzen R, Weissman SM, Kucherlapati R. Isolation of a new clathrin heavy chain gene with muscle-specific expression from the region commonly deleted in velo-cardio-facial syndrome. Human Molecular Genetics. 5: 617-24. PMID 8733128 DOI: 10.1093/Hmg/5.5.617  0.708
1996 Edelmann W, Kucherlapati R. Role of recombination enzymes in mammalian cell survival. Proceedings of the National Academy of Sciences of the United States of America. 93: 6225-7. PMID 8692795 DOI: 10.1073/Pnas.93.13.6225  0.409
1996 Edelmann W, Cohen PE, Kane M, Lau K, Morrow B, Bennett S, Umar A, Kunkel T, Cattoretti G, Chaganti R, Pollard JW, Kolodner RD, Kucherlapati R. Meiotic pachytene arrest in MLH1-deficient mice. Cell. 85: 1125-34. PMID 8674118 DOI: 10.1016/S0092-8674(00)81312-4  0.359
1996 Kuefer MU, Look AT, Williams DC, Valentine V, Naeve CW, Behm FG, Mullersman JE, Yoneda-Kato N, Montgomery K, Kucherlapati R, Morris SW. cDNA cloning, tissue distribution, and chromosomal localization of myelodysplasia/myeloid leukemia factor 2 (MLF2). Genomics. 35: 392-6. PMID 8661158 DOI: 10.1006/Geno.1996.0376  0.448
1996 Van de Ven W, Hagemeijer A, Kucherlapati R, Marynen P. Report of the International Meeting on Chromosome 12 Genes in Cancer. Cytogenetics and Cell Genetics. 73: 25-32. PMID 8646887 DOI: 10.1159/000134309  0.41
1996 Marynen P, Kucherlapati R. Report of the Third International Workshop on Human Chromosome 12 Mapping 1995. Cytogenetics and Cell Genetics. 73: 1-24. PMID 8646874 DOI: 10.1159/000134308  0.386
1996 Johnson DW, Berg JN, Baldwin MA, Gallione CJ, Marondel I, Yoon SJ, Stenzel TT, Speer M, Pericak-Vance MA, Diamond A, Guttmacher AE, Jackson CE, Attisano L, Kucherlapati R, Porteous ME, et al. Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2. Nature Genetics. 13: 189-95. PMID 8640225 DOI: 10.1038/Ng0696-189  0.437
1996 Edelmann W, Zervas M, Costello P, Roback L, Fischer I, Hammarback JA, Cowan N, Davies P, Wainer B, Kucherlapati R. Neuronal abnormalities in microtubule-associated protein 1B mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 93: 1270-5. PMID 8577753 DOI: 10.1073/Pnas.93.3.1270  0.313
1996 Morrow B, Sirotkin H, Goldberg R, Carlson C, Shprintzen R, Kucherlapati R. Association of schizophrenia with VCFS and 22q11 deletions Biological Psychiatry. 39: 540. DOI: 10.1016/0006-3223(96)84088-1  0.662
1995 Renault B, Lieman J, Ward D, Krauter K, Kucherlapati R. Localization of the human achaete-scute homolog gene (ASCL1) distal to phenylalanine hydroxylase (PAH) and proximal to tumor rejection antigen (TRA1) on chromosome 12q22-q23. Genomics. 30: 81-3. PMID 8595908 DOI: 10.1006/Geno.1995.0012  0.457
1995 Miller PL, Nadkarni PM, Kidd KK, Cheung K, Ward DC, Banks A, Bray-Ward P, Cupelli L, Herdman V, Marondel I, Montgomery K, Renault B, Yoon SJ, Krauter KS, Kucherlapati R. Internet-based support for bioscience research: a collaborative genome center for human chromosome 12. Journal of the American Medical Informatics Association : Jamia. 2: 351-64. PMID 8581551 DOI: 10.1136/Jamia.1995.96157828  0.363
1995 Davies RL, Yoon SJ, Weissenbach J, Ward D, Krauter K, Kucherlapati R. Physical mapping of the human ELA1 gene between D12S361 and D12S347 on chromosome 12q13. Genomics. 29: 766-8. PMID 8575772 DOI: 10.1006/Geno.1995.9939  0.44
1995 Umanoff H, Edelmann W, Pellicer A, Kucherlapati R. The murine N-ras gene is not essential for growth and development. Proceedings of the National Academy of Sciences of the United States of America. 92: 1709-13. PMID 7878045 DOI: 10.1073/Pnas.92.5.1709  0.315
1995 Lindsay EA, Goldberg R, Jurecic V, Morrow B, Carlson C, Kucherlapati RS, Shprintzen RJ, Baldini A. Velo-cardio-facial syndrome: frequency and extent of 22q11 deletions. American Journal of Medical Genetics. 57: 514-22. PMID 7677167 DOI: 10.1002/Ajmg.1320570339  0.378
1995 Fejzo MS, Yoon SJ, Montgomery KT, Rein MS, Weremowicz S, Krauter KS, Dorman TE, Fletcher JA, Mao JI, Moir DT, Kucherlapati RS, Morton CC. Identification of a YAC spanning the translocation breakpoints in uterine leiomyomata, pulmonary chondroid hamartoma, and lipoma: physical mapping of the 12q14-q15 breakpoint region in uterine leiomyomata Genomics. 26: 265-271. PMID 7601452 DOI: 10.1016/0888-7543(95)80210-D  0.358
1995 Engle EC, Marondel I, Houtman WA, de Vries B, Loewenstein A, Lazar M, Ward DC, Kucherlapati R, Beggs AH. Congenital fibrosis of the extraocular muscles (autosomal dominant congenital external ophthalmoplegia): genetic homogeneity, linkage refinement, and physical mapping on chromosome 12. American Journal of Human Genetics. 57: 1086-94. PMID 7485159  0.324
1995 Campbell C, Marondel I, Montgomery K, Krauter K, Kucherlapati R. Unequal homologous recombination of human DNA on a yeast artificial chromosome. Nucleic Acids Research. 23: 3691-5. PMID 7478998 DOI: 10.1093/Nar/23.18.3691  0.361
1994 LeBlanc-Straceski JM, Montgomery KT, Kissel H, Murtaugh L, Tsai P, Ward DC, Krauter KS, Kucherlapati R. Twenty-one polymorphic markers from human chromosome 12 for integration of genetic and physical maps. Genomics. 19: 341-9. PMID 8188264 DOI: 10.1006/Geno.1994.1067  0.342
1994 Pedeutour F, Merscher S, Durieux E, Montgomery K, Krauter K, Clevy JP, Barcelo G, Kucherlapati R, Gaudray P, Turc-Carel C. Mapping of the 12q12-q22 region with respect to tumor translocation breakpoints. Genomics. 22: 512-8. PMID 8001964 DOI: 10.1006/Geno.1994.1424  0.427
1994 Kobayashi H, Montgomery KT, Bohlander SK, Adra CN, Lim BL, Kucherlapati RS, Donis-Keller H, Holt MS, Le Beau MM, Rowley JD. Fluorescence in situ hybridization mapping of translocations and deletions involving the short arm of human chromosome 12 in malignant hematologic diseases. Blood. 84: 3473-82. PMID 7949101 DOI: 10.1182/Blood.V84.10.3473.3473  0.405
1994 Carter SA, Bryce SD, Munro CS, Healy E, Bashir R, Weissenbach J, LeBlanc-Straceski J, Kucherlapati R, Stephenson A, Rees JL. Linkage analyses in British pedigrees suggest a single locus for Darier disease and narrow the location to the interval between D12S105 and D12S129. Genomics. 24: 378-82. PMID 7698764 DOI: 10.1006/Geno.1994.1632  0.362
1994 Yoon SJ, LeBlanc-Straceski J, Ward D, Krauter K, Kucherlapati R. Organization of the human keratin type II gene cluster at 12q13. Genomics. 24: 502-8. PMID 7536183 DOI: 10.1006/Geno.1994.1659  0.409
1993 Das Gupta R, Morrow B, Marondel I, Parimoo S, Goei VL, Gruen J, Weissman S, Skoultchi A, Kucherlapati R. An integrated approach for identifying and mapping human genes. Proceedings of the National Academy of Sciences of the United States of America. 90: 4364-8. PMID 8506274 DOI: 10.1073/Pnas.90.10.4364  0.432
1993 McKusik VA, Kucherlapati RS, Ruddle FH. Genomics: stock-taking after 5 years. Genomics. 15: 1-2. PMID 8432520 DOI: 10.1006/geno.1993.1001  0.357
1993 Montgomery KT, LeBlanc JM, Tsai P, McNinch JS, Ward DC, de Jong PJ, Kucherlapati R, Krauter KS. Characterization of two chromosome 12 cosmid libraries and development of STSs from cosmids mapped by FISH. Genomics. 17: 682-93. PMID 8244385 DOI: 10.1006/Geno.1993.1390  0.423
1993 Morrow B, Kucherlapati R. Gene targeting in mammalian cells by homologous recombination. Current Opinion in Biotechnology. 4: 577-82. PMID 7764209 DOI: 10.1016/0958-1669(93)90080-G  0.352
1992 Yoon SJ, Seiler SH, Kucherlapati R, Leinwand L. Organization of the human skeletal myosin heavy chain gene cluster. Proceedings of the National Academy of Sciences of the United States of America. 89: 12078-82. PMID 1465443 DOI: 10.1073/Pnas.89.24.12078  0.584
1991 Campbell C, Gulati R, Nandi AK, Floy K, Hieter P, Kucherlapati RS. Generation of a nested series of interstitial deletions in yeast artificial chromosomes carrying human DNA. Proceedings of the National Academy of Sciences of the United States of America. 88: 5744-8. PMID 2062854 DOI: 10.1073/Pnas.88.13.5744  0.424
1991 Schwartz F, Maeda N, Smithies O, Hickey R, Edelmann W, Skoultchi A, Kucherlapati R. A dominant positive and negative selectable gene for use in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 10416-20. PMID 1720540 DOI: 10.1073/Pnas.88.23.10416  0.358
1989 Kucherlapati RS. Homologous recombination in mammalian somatic cells. Progress in Nucleic Acid Research and Molecular Biology. 36: 301-10. PMID 2660192 DOI: 10.1016/S0079-6603(08)60178-6  0.341
1987 Kucherlapati R. Gene replacement by homologous recombination in mammalian cells. Somatic Cell and Molecular Genetics. 13: 447-9. PMID 3484087 DOI: 10.1007/Bf01534946  0.384
1987 Song KY, Schwartz F, Maeda N, Smithies O, Kucherlapati R. Accurate modification of a chromosomal plasmid by homologous recombination in human cells. Proceedings of the National Academy of Sciences of the United States of America. 84: 6820-4. PMID 2821545 DOI: 10.1073/Pnas.84.19.6820  0.45
1986 Ayares D, Chekuri L, Song KY, Kucherlapati R. Sequence homology requirements for intermolecular recombination in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 83: 5199-203. PMID 3523485 DOI: 10.1073/Pnas.83.14.5199  0.393
1986 Rauth S, Song KY, Ayares D, Wallace L, Moore PD, Kucherlapati R. Transfection and homologous recombination involving single-stranded DNA substrates in mammalian cells and nuclear extracts. Proceedings of the National Academy of Sciences of the United States of America. 83: 5587-91. PMID 3461451 DOI: 10.1073/Pnas.83.15.5587  0.313
1985 Song KY, Chekuri L, Rauth S, Ehrlich S, Kucherlapati R. Effect of double-strand breaks on homologous recombination in mammalian cells and extracts. Molecular and Cellular Biology. 5: 3331-6. PMID 3870133 DOI: 10.1128/Mcb.5.12.3331  0.392
1985 Smithies O, Gregg RG, Boggs SS, Koralewski MA, Kucherlapati RS. Insertion of DNA sequences into the human chromosomal beta-globin locus by homologous recombination. Nature. 317: 230-4. PMID 2995814 DOI: 10.1038/317230A0  0.423
1985 Kucherlapati RS, Spencer J, Moore PD. Homologous recombination catalyzed by human cell extracts. Molecular and Cellular Biology. 5: 714-20. PMID 2985967 DOI: 10.1128/Mcb.5.4.714  0.353
1984 Kucherlapati RS, Eves EM, Song KY, Morse BS, Smithies O. Homologous recombination between plasmids in mammalian cells can be enhanced by treatment of input DNA. Proceedings of the National Academy of Sciences of the United States of America. 81: 3153-7. PMID 6328502 DOI: 10.1073/Pnas.81.10.3153  0.354
1984 Clough DW, Morse BS, Kucherlapati RS, Davidson RL. Insulin-induced reactivation of an inactive herpes simplex thymidine kinase gene. Proceedings of the National Academy of Sciences of the United States of America. 81: 838-42. PMID 6322172 DOI: 10.1073/Pnas.81.3.838  0.312
1984 Kucherlapati RS, Ayares D, Hanneken A, Noonan K, Rauth S, Spencer JM, Wallace L, Moore PD. Homologous recombination in monkey cells and human cell-free extracts. Cold Spring Harbor Symposia On Quantitative Biology. 49: 191-7. PMID 6099233 DOI: 10.1101/Sqb.1984.049.01.022  0.31
1984 Rauth S, Kucherlapati RS. Expression of DNA transferred into mammalian cells Journal of Biosciences. 6: 543-567. DOI: 10.1007/Bf02703905  0.362
1983 Roginski RS, Skoultchi AI, Henthorn P, Smithies O, Hsiung N, Kucherlapati R. Coordinate modulation of transfected HSV thymidine kinase and human globin genes. Cell. 35: 149-55. PMID 6313221 DOI: 10.1016/0092-8674(83)90217-9  0.392
1983 Hwang SP, Kucherlapati RS. Events preceding stable integration of SV40 genomes in a human cell line. Somatic Cell Genetics. 9: 457-68. PMID 6312621 DOI: 10.1007/Bf01543046  0.395
1982 Gilboa E, Kolbe M, Noonan K, Kucherlapati R. Construction of a mammalian transducing vector from the genome of Moloney murine leukemia virus. Journal of Virology. 44: 845-51. PMID 7176018 DOI: 10.1128/Jvi.44.3.845-851.1982  0.362
1982 Davies RL, Fuhrer-Krusi S, Kucherlapati RS. Modulation of transfected gene expression mediated by changes in chromatin structure. Cell. 31: 521-9. PMID 6186385 DOI: 10.1016/0092-8674(82)90308-7  0.345
1982 Hsiung N, Roginski RS, Henthorn P, Smithies O, Kucherlapati R, Skoultchi AI. Introduction and expression of a fetal human globin gene in mouse fibroblasts. Molecular and Cellular Biology. 2: 401-11. PMID 6180305 DOI: 10.1128/Mcb.2.4.401  0.384
1980 Hsiung N, Kucherlapati R. Histone gene expression and chromatin structure in mammalian cell hybrids. The Journal of Cell Biology. 87: 227-36. PMID 7419591 DOI: 10.1083/Jcb.87.1.227  0.361
1980 Warrick H, Hsiung N, Shows TB, Kucherlapati R. DNA-mediated cotransfer of unlinked mammalian cell markers into mouse L cells. The Journal of Cell Biology. 86: 341-6. PMID 6932400 DOI: 10.1083/Jcb.86.1.341  0.355
1980 Pyati J, Kucherlapati RS, Skoultchi AI. Activation of human beta-globin genes from nonerythroid cells by fusion with murine erythroleukemia cells. Proceedings of the National Academy of Sciences of the United States of America. 77: 3435-9. PMID 6932030 DOI: 10.1073/Pnas.77.6.3435  0.424
1980 Hsiung N, Warrick H, deRiel JK, Tuan D, Forget BG, Skoultchi A, Kucherlapati R. Cotransfer of circular and linear prokaryotic and eukaryotic DNA sequences into mouse cells. Proceedings of the National Academy of Sciences of the United States of America. 77: 4852-6. PMID 6254042 DOI: 10.1073/Pnas.77.8.4852  0.368
1980 Davies RL, Grosse VA, Kucherlapati R, Bothwell M. Genetic analysis of epidermal growth factor action: assignment of human epidermal growth factor receptor gene to chromosome 7. Proceedings of the National Academy of Sciences of the United States of America. 77: 4188-92. PMID 6254014 DOI: 10.1073/Pnas.77.7.4188  0.428
1980 Hwang SP, Kucherlapati R. Localization and organization of integrated simian virus 40 sequences in a human cell line. Virology. 105: 196-204. PMID 6251605 DOI: 10.1016/0042-6822(80)90167-1  0.4
1979 Kucherlapati R, Shin SI. Genetic control of tumorigenicity in interspecific mammalian cell hybrids. Cell. 16: 639-48. PMID 455444 DOI: 10.1016/0092-8674(79)90037-0  0.42
1979 Wolin SL, Kucherlapati RS. Expression of microtubule networks in normal cells, transformed cells, and their hybrids. The Journal of Cell Biology. 82: 76-85. PMID 383725 DOI: 10.1083/Jcb.82.1.76  0.334
1978 Turner BM, Smith M, Turner VS, Kucherlapati RS, Ruddle FH, Hirschhorn K. Assignment of the gene locus for human alpha-L-fucosidase to chromosome 1 by analysis of somatic cell hybrids. Somatic Cell Genetics. 4: 45-54. PMID 628884 DOI: 10.1007/Bf01546492  0.381
1978 Kucherlapati R, Tepper R, Granelli-Piperno A, Reich E. Modulation and mapping of a human plasminogen activator by cell fusion. Cell. 15: 1331-40. PMID 569557 DOI: 10.1016/0092-8674(78)90058-2  0.406
1978 Levy R, Dilley J, Sikora K, Kucherlapati R. Mouse-human hybridomas. The conversion of non-secreting human B cells into Ig secretors. Current Topics in Microbiology and Immunology. 81: 170-2. PMID 308437 DOI: 10.1007/978-3-642-67448-8_27  0.322
1978 Kucherlapati R, Hwang SP, Shimizu N, McDougall JK, Botchan MR. Another chromosomal assignment for a simian virus 40 integration site in human cells. Proceedings of the National Academy of Sciences of the United States of America. 75: 4460-4. PMID 212753 DOI: 10.1073/Pnas.75.9.4460  0.346
1977 Willecke K, Teber T, Kucherlapati RS, Ruddle FH. Human mitochondrial thymidine kinase is coded for by a gene on chromosome 16 of the nucleus. Somatic Cell Genetics. 3: 237-45. PMID 605384 DOI: 10.1007/Bf01538743  0.683
1977 Shimizu N, Giles RE, Kucherlapati RS, Shimizu Y, Ruddle FH. Somatic cell genetic assignment of the human gene for mitochondrial NADP-linked isocitrate dehydrogenase to the long arm of chromosome 15. Somatic Cell Genetics. 3: 47-60. PMID 564083 DOI: 10.1007/Bf01550986  0.607
1977 Deisseroth A, Nienhuis A, Turner P, Velez R, Anderson WF, Ruddle F, Lawrence J, Creagan R, Kucherlapati R. Localization of the human alpha-globin structural gene to chromosome 16 in somatic cell hybrids by molecular hybridization assay. Cell. 12: 205-18. PMID 561664 DOI: 10.1016/0092-8674(77)90198-2  0.61
1976 Shimizu N, Kucherlapati RS, Ruddle FH. Assignment of the human gene for tryptophanyl-tRNA synthetase using human-mouse somatic cell hybrids. Cytogenetics and Cell Genetics. 16: 223-6. PMID 1088821 DOI: 10.1159/000130596  0.584
1976 Willecke K, Reber T, Kucherlapati RS, Ruddle FH. Segregation of human mitochondrial thymidine thymidine kinase activity in human-mouse somatic cell hybrids. Birth Defects Original Article Series. 12: 252-5. PMID 1024620  0.6
1976 Shimizu N, Shimizu Y, Kucherlapati RS, Ruddle FH. Immunochemical detection of human enzymes in hybrid cells. Cell. 7: 123-30. PMID 985736 DOI: 10.1016/0092-8674(76)90262-2  0.54
1976 Anderson WF, Deisseroth AB, Velez R, Nienhuis AW, Ruddle FH, Kucherlapati RS. A new technique for mapping the human hemoglobin genes. Cytogenetics and Cell Genetics. 16: 367-71. PMID 975910 DOI: 10.1159/000130634  0.521
1976 Willecke K, Reber T, Kucherlapati RS, Ruddle FH. Segregation of human mitochondrial thymidine kinase activity in human-mouse somatic cell hybrids. Cytogenetics and Cell Genetics. 16: 252-5. PMID 975885 DOI: 10.1159/000130604  0.634
1976 Turner VS, Turner BM, Kucherlapati R, Ruddle FH, Hirschhorn K. Assignment of the human alpha-L-fucosidase gene locus to chromosome 1 by use of a "clone panel". Cytogenetics and Cell Genetics. 16: 238-40. PMID 975883 DOI: 10.1159/000130600  0.557
1976 Kucherlapati RS, Ruddle FH. Assignment of the human genes for mannose phosphate isomerase, pyruvate kinase (M2), and hexosaminidase-A to chromosome 15. Cytogenetics and Cell Genetics. 16: 181-3. PMID 975875 DOI: 10.1159/000130585  0.564
1976 Shimizu N, Kucherlapati RS, Ruddle FH. Assignment of a human gene for tryptophanyl-tRNA synthetase to chromosome 14 using human-mouse somatic cell hybrids. Somatic Cell Genetics. 2: 345-57. PMID 829178 DOI: 10.1007/Bf01538839  0.571
1976 Klobutcher LA, Nichols EA, Kucherlapati RS, Ruddle FH. Assignment of the gene for human adenosine kinase to chromosome 10 using a somatic cell hybrid clone panel. Birth Defects Original Article Series. 12: 171-4. PMID 192365  0.356
1976 McDougall JK, Gallimore PH, Dunn AR, Webb TP, Kucherlapati RS, Nichols EA, Ruddle FH. Mapping viral integration sites in somatic cell hybrids. Cytogenetics and Cell Genetics. 16: 206-10. PMID 185015 DOI: 10.1159/000130592  0.476
1976 Klobutcher LA, Nichols EA, Kucherlapati RS, Ruddle FH. Assignment of the gene for human adenosine kinase to chromosome 10 using a somatic cell hybrid clone panel. Cytogenetics and Cell Genetics. 16: 171-4. PMID 185014 DOI: 10.1159/000130582  0.603
1976 Satlin A, Kucherlapati R, Ruddle FH. Assignment of the gene for human uridine monophosphate kinase to chromosome 1 using somatic cell hybrid clone panels. Cytogenetics and Cell Genetics. 15: 146-52. PMID 172293 DOI: 10.1159/000130513  0.606
1976 McDougall JK, Elsevier SM, Kucherlapati RS, Ruddle FH. Regional localization of human genes in virus-induced uncoiler regions. Cytogenetics and Cell Genetics. 14: 372-4. PMID 172292 DOI: 10.1159/000130388  0.513
1976 Faber HE, Kucherlapati RS, Poulik MD, Ruddle FH, Smithies O. beta2-microglobulin locus on human chromosome 15. Somatic Cell Genetics. 2: 141-53. PMID 69326 DOI: 10.1007/Bf01542627  0.574
1976 Schacter B, Kucherlapati RS, Ruddle FH. Synteny of the loci for beta2-microglobulin and PKM2 in man-mouse somatic cell hybrid subclones. Cytogenetics and Cell Genetics. 16: 215-8. PMID 61838 DOI: 10.1159/000130594  0.502
1976 Kucherlapati RS, Faber HE, Poulik MD, Ruddle FH, Smithies O. Assignment of the gene for beta-2-microglobulin to human chromosome 15. Cytogenetics and Cell Genetics. 16: 178-80. PMID 61837 DOI: 10.1159/000130584  0.568
1976 Friend KK, Dorman BP, Kucherlapati RS, Ruddle FH. Detection of interspecific translocations in mouse-human hybrids by alkaline Giemsa staining. Experimental Cell Research. 99: 31-6. PMID 57063 DOI: 10.1016/0014-4827(76)90676-5  0.581
1975 Kucherlapati RS, Creagan RP, Nichols EA, Borgaonkar DS, Ruddle FH. Synteny relationships of four human genes: mannose phosphate isomerase to pyruvate kinase-3 and triose phophate isomerase to lactate dehydrogenase-B. Cytogenetics and Cell Genetics. 14: 364-7. PMID 1192819 DOI: 10.1159/000130385  0.333
1975 Kucherlapati RS, Baker RM, Ruddle FH. Ouabain as a selective agent in the isolation of somatic cell hybrids. Cytogenetics and Cell Genetics. 14: 362-3. PMID 1192818 DOI: 10.1159/000130384  0.472
1975 Kucherlapati RS, Ruddle FH. Mammalian somatic hybrids and human gene mapping. Annals of Internal Medicine. 83: 553-60. PMID 1101764 DOI: 10.7326/0003-4819-83-4-553  0.609
1975 Gilbert F, Kucherlapati R, Creagan RP, Murnane MJ, Darlington GJ, Ruddle FH. Tay-Sachs' and Sandhoff's diseases: the assignment of genes for hexosaminidase A and B to individual human chromosomes. Proceedings of the National Academy of Sciences of the United States of America. 72: 263-7. PMID 1054503 DOI: 10.1073/Pnas.72.1.263  0.58
1975 Elsevier SM, Kucherlapati RS, Nichols EA, Willecke K, Creagan RP, Giles RE, McDougall JK, Ruddle FH. Assigment and regional localization of a gene coding for galactokinase to human chromosome 17q21-22. Cytogenetics and Cell Genetics. 14: 287-9. PMID 172290 DOI: 10.1159/000130365  0.673
1975 Kucherlapati RS, Hilwig I, Gropp A, Ruddle FH. Mammalian chromosome identification in interspecific hybride cells using "Hoechst 33258". Human Genetics. 27: 9-14. DOI: 10.1007/Bf00283498  0.439
1974 Ruddle FH, Kucherlapati RS. Hybrid cells and human genes. Scientific American. 231: 36-44. PMID 4846961 DOI: 10.1038/Scientificamerican0774-36  0.58
1974 Gilbert F, Kucherlapati R, Murnane MJ, Darlington GJ, Creagan R, Ruddle FH. Proceedings: Assignment of a locus involved in the expression of hexosaminidase A to chromosome 7 in man. Cytogenetics and Cell Genetics. 13: 96-6. PMID 4827504 DOI: 10.1159/000130245  0.399
1974 Gilbert F, Kucherlapati R, Creagan R, Murnane MJ, Darlington GJ, Ruddle FH. Proceedings: Hexosaminidase B: assignment of a locus involved in its expression to chromosome 5 in man. Cytogenetics and Cell Genetics. 13: 93-5. PMID 4827503 DOI: 10.1159/000130244  0.537
1974 Creagan RP, Carritt B, Chen S, Kucherlapati R, McMorris FA, Ricciuti F, Tan YH, Tischfield JA, Ruddle FH. Proceedings: Confirmation of the synteny of the human genes for cytoplasmic isocitrate dehydrogenase and cytoplasmic malate dehydrogenase and assignment to chromosome 2. Cytogenetics and Cell Genetics. 13: 79-82. PMID 4827500 DOI: 10.1159/000130239  0.755
1974 Kucherlapati R, McDougall JK, Ruddle FH. Proceedings: Regional localization of the human genes for thymidine kinase, lactate dehydrogenase-A, and esterase-A. Cytogenetics and Cell Genetics. 13: 108-10. PMID 4827473 DOI: 10.1159/000130249  0.53
1974 Elsevier SM, Kucherlapati RS, Nichols EA, Creagan RP, Giles RE, Ruddle FH, Willecke K, McDougall JK. Assignment of the gene for galactokinase to human chromosome 17 and its regional localisation to band q21-22. Nature. 251: 633-6. PMID 4371022 DOI: 10.1038/251633A0  0.703
1974 Gilbert F, Kucherlapati R, Murnane MJ, Darlington GJ, Creagan R, Ruddle FH. Assignment of a locus involved in the expression of hexosaminidase a to chromosome 7 in man Cytogenetic and Genome Research. 13: 96-99. DOI: 10.1159/000130245  0.5
1973 McDougall JK, Kucherlapati R, Ruddle FH. Localization and induction of the human thymidine kinase gene by adenovirus 12. Nature: New Biology. 245: 172-5. PMID 4126392 DOI: 10.1038/Newbio245172A0  0.61
Low-probability matches (unlikely to be authored by this person)
2019 Yang L, Wang S, Lee JJ, Lee S, Lee E, Shinbrot E, Wheeler DA, Kucherlapati R, Park PJ. An enhanced genetic model of colorectal cancer progression history. Genome Biology. 20: 168. PMID 31416464 DOI: 10.1186/S13059-019-1782-4  0.3
1976 Kucherlapati RS, Faber HE, Poulik MD, Ruddle FH, Simithes O. Assignment of the gene for beta-2-microglogulin to human chromosome 15. Birth Defects Original Article Series. 12: 178-80. PMID 66942  0.298
2015 Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, ... ... Kucherlapati R, et al. Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. The New England Journal of Medicine. 372: 2481-98. PMID 26061751 DOI: 10.1056/Nejmoa1402121  0.298
2001 Kucherlapati R, Lin DP, Edelmann W. Mouse models for human familial adenomatous polyposis. Seminars in Cancer Biology. 11: 219-25. PMID 11407946 DOI: 10.1006/Scbi.2001.0368  0.297
2007 Kucherlapati M, Nguyen A, Kuraguchi M, Yang K, Fan K, Bronson R, Wei K, Lipkin M, Edelmann W, Kucherlapati R. Tumor progression in Apc(1638N) mice with Exo1 and Fen1 deficiencies. Oncogene. 26: 6297-306. PMID 17452984 DOI: 10.1038/Sj.Onc.1210453  0.296
2008 Joshi VA, Kucherlapati R. Genetics and genomics in the practice of medicine. Gastroenterology. 134: 1284-8. PMID 18471501 DOI: 10.1053/J.Gastro.2008.03.046  0.296
1999 Yang Y, Piek E, Massimi A, Yang R, Heyer J, Kucherlapati R, Roberts AB, Bottinger EP. Genetic/genomic analysis of signal transduction pathways using cDNA microarray technology Nature Genetics. 23: 34-34. DOI: 10.1038/14270  0.296
1985 Strazdis J, Lanahan A, Johnson DE, Bothwell M, Kucherlapati R. The epidermal growth factor (EGF) receptor gene studied using gene transfer. The International Journal of Neuroscience. 26: 129-40. PMID 2987144 DOI: 10.3109/00207458508985611  0.294
2010 Cirstea IC, Kutsche K, Dvorsky R, Gremer L, Carta C, Horn D, Roberts AE, Lepri F, Merbitz-Zahradnik T, König R, Kratz CP, Pantaleoni F, Dentici ML, Joshi VA, Kucherlapati RS, et al. A restricted spectrum of NRAS mutations causes Noonan syndrome. Nature Genetics. 42: 27-9. PMID 19966803 DOI: 10.1038/Ng.497  0.294
1986 Moore PD, Song KY, Chekuri L, Wallace L, Kucherlapati RS. Homologous recombination in a Chinese hamster X-ray-sensitive mutant. Mutation Research. 160: 149-55. PMID 3951458 DOI: 10.1016/0027-5107(86)90038-2  0.294
2014 Liu Y, Patel L, Mills GB, Lu KH, Sood AK, Ding L, Kucherlapati R, Mardis ER, Levine DA, Shmulevich I, Broaddus RR, Zhang W. Clinical significance of CTNNB1 mutation and Wnt pathway activation in endometrioid endometrial carcinoma. Journal of the National Cancer Institute. 106. PMID 25214561 DOI: 10.1093/Jnci/Dju245  0.293
1999 Kucherlapati R. Role of colon cancer genes in development Nature Genetics. 23: 23-23. DOI: 10.1038/14244  0.293
2003 Yang K, Fan K, Kurihara N, Shinozaki H, Rigas B, Augenlicht L, Kopelovich L, Edelmann W, Kucherlapati R, Lipkin M. Regional response leading to tumorigenesis after sulindac in small and large intestine of mice with Apc mutations. Carcinogenesis. 24: 605-11. PMID 12663524 DOI: 10.1093/Carcin/24.3.605  0.293
2002 Velcich A, Yang W, Heyer J, Fragale A, Nicholas C, Viani S, Kucherlapati R, Lipkin M, Yang K, Augenlicht L. Colorectal cancer in mice genetically deficient in the mucin Muc2. Science (New York, N.Y.). 295: 1726-9. PMID 11872843 DOI: 10.1126/Science.1069094  0.293
2001 Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, Devon K, Dewar K, Doyle M, Fitzhugh W, Funke R, Gage D, Harris K, Heaford A, Howland J, ... ... Kucherlapati RS, et al. Erratum: Initial sequencing and analysis of the human genome: International Human Genome Sequencing Consortium (Nature (2001) 409 (860-921)) Nature. 412: 565-566. DOI: 10.1038/35087627  0.292
2009 Hung KE, Faca V, Song K, Sarracino DA, Richard LG, Krastins B, Forrester S, Porter A, Kunin A, Mahmood U, Haab BB, Hanash SM, Kucherlapati R. Comprehensive proteome analysis of an Apc mouse model uncovers proteins associated with intestinal tumorigenesis. Cancer Prevention Research (Philadelphia, Pa.). 2: 224-33. PMID 19240248 DOI: 10.1158/1940-6207.Capr-08-0153  0.292
1987 Ganea D, Moore P, Chekuri L, Kucherlapati R. Characterization of an ATP-dependent DNA strand transferase from human cells. Molecular and Cellular Biology. 7: 3124-30. PMID 2823121 DOI: 10.1128/Mcb.7.9.3124  0.292
1996 Papolos DF, Faedda GL, Veit S, Goldberg R, Morrow B, Kucherlapati R, Shprintzen RJ. Bipolar spectrum disorders in patients diagnosed with velo-cardio-facial syndrome: does a hemizygous deletion of chromosome 22q11 result in bipolar affective disorder? The American Journal of Psychiatry. 153: 1541-7. PMID 8942449 DOI: 10.1176/Ajp.153.12.1541  0.291
2006 Joshi VA, Kucherlapati R. Lung cancer genetics and pharmacogenomics. Cytogenetic and Genome Research. 115: 298-302. PMID 17124413 DOI: 10.1159/000095927  0.291
2014 Parfenov M, Pedamallu CS, Gehlenborg N, Freeman SS, Danilova L, Bristow CA, Lee S, Hadjipanayis AG, Ivanova EV, Wilkerson MD, Protopopov A, Yang L, Seth S, Song X, Tang J, ... ... Kucherlapati R, et al. Characterization of HPV and host genome interactions in primary head and neck cancers. Proceedings of the National Academy of Sciences of the United States of America. 111: 15544-9. PMID 25313082 DOI: 10.1073/Pnas.1416074111  0.289
2015 Lu H, Pantazi A, Dogruluk T, Dogruluk A, Creighton C, Mills GB, Kucherlapati R, Scott KL. Abstract 1099: High-throughput engineering and functional annotation of cancer fusion genes Cancer Research. 75: 1099-1099. DOI: 10.1158/1538-7445.Am2015-1099  0.288
2011 McDonald DA, Shenkar R, Shi C, Stockton RA, Akers AL, Kucherlapati MH, Kucherlapati R, Brainer J, Ginsberg MH, Awad IA, Marchuk DA. A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease. Human Molecular Genetics. 20: 211-22. PMID 20940147 DOI: 10.1093/Hmg/Ddq433  0.286
2003 Young LC, Peters AC, Maeda T, Edelmann W, Kucherlapati R, Andrew SE, Tron VA. DNA mismatch repair protein Msh6 is required for optimal levels of ultraviolet-B-induced apoptosis in primary mouse fibroblasts. The Journal of Investigative Dermatology. 121: 876-80. PMID 14632208 DOI: 10.1046/J.1523-1747.2003.12486.X  0.286
1984 Smithies O, Koralewski MA, Song KY, Kucherlapati RS. Homologous recombination with DNA introduced into mammalian cells. Cold Spring Harbor Symposia On Quantitative Biology. 49: 161-70. PMID 6597754 DOI: 10.1101/Sqb.1984.049.01.019  0.285
2011 Xi R, Hadjipanayis AG, Luquette LJ, Kim TM, Lee E, Zhang J, Johnson MD, Muzny DM, Wheeler DA, Gibbs RA, Kucherlapati R, Park PJ. Copy number variation detection in whole-genome sequencing data using the Bayesian information criterion. Proceedings of the National Academy of Sciences of the United States of America. 108: E1128-36. PMID 22065754 DOI: 10.1073/Pnas.1110574108  0.285
2008 Yang K, Lamprecht SA, Shinozaki H, Fan K, Yang W, Newmark HL, Kopelovich L, Edelmann W, Jin B, Gravaghi C, Augenlicht L, Kucherlapati R, Lipkin M. Dietary calcium and cholecalciferol modulate cyclin D1 expression, apoptosis, and tumorigenesis in intestine of adenomatous polyposis coli1638N/+ mice. The Journal of Nutrition. 138: 1658-63. PMID 18716166 DOI: 10.1093/Jn/138.9.1658  0.284
2010 Chan AT, Baba Y, Shima K, Nosho K, Chung DC, Hung KE, Mahmood U, Madden K, Poss K, Ranieri A, Shue D, Kucherlapati R, Fuchs CS, Ogino S. Cathepsin B expression and survival in colon cancer: implications for molecular detection of neoplasia. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 19: 2777-85. PMID 20833970 DOI: 10.1158/1055-9965.Epi-10-0529  0.283
1983 Davies RL, Rifkin DB, Tepper R, Miller A, Kucherlapati R. A polypeptide secreted by transformed cells that modulates human plasminogen activator production. Science (New York, N.Y.). 221: 171-3. PMID 6682999 DOI: 10.1126/Science.6682999  0.281
2006 Kucherlapati MH, Nguyen AA, Bronson RT, Kucherlapati RS. Inactivation of conditional Rb by Villin-Cre leads to aggressive tumors outside the gastrointestinal tract. Cancer Research. 66: 3576-83. PMID 16585182 DOI: 10.1158/0008-5472.Can-05-2699  0.28
1997 Johnson L, Greenbaum D, Cichowski K, Mercer K, Murphy E, Schmitt E, Bronson RT, Umanoff H, Edelmann W, Kucherlapati R, Jacks T. K-ras is an essential gene in the mouse with partial functional overlap with N-ras. Genes & Development. 11: 2468-81. PMID 9334313 DOI: 10.1101/Gad.11.19.2468  0.28
1976 Turner VS, Turner BM, Kucherlapati R, Ruddle FH, Hirschhorn K. Assignment of the human alpha-l-fucosidase gene locus to chromosome 1 by use of a "clone panel". Birth Defects Original Article Series. 12: 238-40. PMID 1024618  0.279
2008 Morita H, Rehm HL, Menesses A, McDonough B, Roberts AE, Kucherlapati R, Towbin JA, Seidman JG, Seidman CE. Shared genetic causes of cardiac hypertrophy in children and adults. The New England Journal of Medicine. 358: 1899-908. PMID 18403758 DOI: 10.1056/Nejmoa075463  0.279
2017 Jahid S, Sun J, Gelincik O, Blecua P, Edelmann W, Kucherlapati R, Zhou K, Jasin M, Gümüş ZH, Lipkin SM. Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair. Oncotarget. PMID 28548965 DOI: 10.18632/oncotarget.17776  0.278
2010 Lee I, Pecinova A, Pecina P, Neel BG, Araki T, Kucherlapati R, Roberts AE, Hüttemann M. A suggested role for mitochondria in Noonan syndrome. Biochimica Et Biophysica Acta. 1802: 275-83. PMID 19835954 DOI: 10.1016/J.Bbadis.2009.10.005  0.278
1996 Papolos DF, Goldberg R, Faedda G, Veit S, Shprintzen R, Kucherlapati R, Morrow B. Psychiatric illness in children and adults with Velo-cardio-facial syndrome with/without 22q11 deletions Psychiatric Genetics. 6: 172. DOI: 10.1097/00041444-199623000-00102  0.277
2002 Costa RM, Federov NB, Kogan JH, Murphy GG, Stern J, Ohno M, Kucherlapati R, Jacks T, Silva AJ. Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1. Nature. 415: 526-30. PMID 11793011 DOI: 10.1038/Nature711  0.277
2007 Funke BH, Lencz T, Finn CT, DeRosse P, Poznik GD, Plocik AM, Kane J, Rogus J, Malhotra AK, Kucherlapati R. Analysis of TBX1 variation in patients with psychotic and affective disorders. Molecular Medicine (Cambridge, Mass.). 13: 407-14. PMID 17622328 DOI: 10.2119/2006-00119.FUNKE  0.276
1999 Schrader CE, Edelmann W, Kucherlapati R, Stavnezer J. Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes. The Journal of Experimental Medicine. 190: 323-30. PMID 10430621 DOI: 10.1084/Jem.190.3.323  0.275
2002 Girnun GD, Smith WM, Drori S, Sarraf P, Mueller E, Eng C, Nambiar P, Rosenberg DW, Bronson RT, Edelmann W, Kucherlapati R, Gonzalez FJ, Spiegelman BM. APC-dependent suppression of colon carcinogenesis by PPARgamma. Proceedings of the National Academy of Sciences of the United States of America. 99: 13771-6. PMID 12370429 DOI: 10.1073/Pnas.162480299  0.274
2002 Bourdon V, Naef F, Rao PH, Reuter V, Mok SC, Bosl GJ, Koul S, Murty VV, Kucherlapati RS, Chaganti RS. Genomic and expression analysis of the 12p11-p12 amplicon using EST arrays identifies two novel amplified and overexpressed genes. Cancer Research. 62: 6218-23. PMID 12414650  0.273
2007 Burdick KE, Funke B, Goldberg JF, Bates JA, Jaeger J, Kucherlapati R, Malhotra AK. COMT genotype increases risk for bipolar I disorder and influences neurocognitive performance. Bipolar Disorders. 9: 370-6. PMID 17547583 DOI: 10.1111/J.1399-5618.2007.00384.X  0.273
2006 Hung KE, Kho AT, Sarracino D, Richard LG, Krastins B, Forrester S, Haab BB, Kohane IS, Kucherlapati R. Mass spectrometry-based study of the plasma proteome in a mouse intestinal tumor model. Journal of Proteome Research. 5: 1866-78. PMID 16889408 DOI: 10.1021/Pr060120R  0.272
2006 Sequist LV, Joshi VA, Jänne PA, Bell DW, Fidias P, Lindeman NI, Louis DN, Lee JC, Mark EJ, Longtine J, Verlander P, Kucherlapati R, Meyerson M, Haber DA, Johnson BE, et al. Epidermal growth factor receptor mutation testing in the care of lung cancer patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 4403s-4408s. PMID 16857818 DOI: 10.1158/1078-0432.Ccr-06-0099  0.272
1987 Ayares D, Ganea D, Chekuri L, Campbell CR, Kucherlapati R. Repair of single-stranded DNA nicks, gaps, and loops in mammalian cells. Molecular and Cellular Biology. 7: 1656-62. PMID 3474515 DOI: 10.1128/Mcb.7.5.1656  0.272
2008 Gravaghi C, Bo J, Laperle KM, Quimby F, Kucherlapati R, Edelmann W, Lamprecht SA. Obesity enhances gastrointestinal tumorigenesis in Apc-mutant mice. International Journal of Obesity (2005). 32: 1716-9. PMID 18725892 DOI: 10.1038/Ijo.2008.149  0.271
2013 Kucherlapati MH, Esfahani S, Habibollahi P, Wang J, Still ER, Bronson RT, Mahmood U, Kucherlapati RS. Genotype directed therapy in murine mismatch repair deficient tumors. Plos One. 8: e68817. PMID 23935891 DOI: 10.1371/Journal.Pone.0068817  0.271
2003 Yang YC, Piek E, Zavadil J, Liang D, Xie D, Heyer J, Pavlidis P, Kucherlapati R, Roberts AB, Böttinger EP. Hierarchical model of gene regulation by transforming growth factor beta. Proceedings of the National Academy of Sciences of the United States of America. 100: 10269-74. PMID 12930890 DOI: 10.1073/Pnas.1834070100  0.271
2007 Kratz CP, Niemeyer CM, Thomas C, Bauhuber S, Matejas V, Bergsträsser E, Flotho C, Flores NJ, Haas O, Hasle H, van den Heuvel-Eibrink MM, Kucherlapati RS, Lang P, Roberts AE, Starý J, et al. Mutation analysis of Son of Sevenless in juvenile myelomonocytic leukemia. Leukemia. 21: 1108-9. PMID 17315019 DOI: 10.1038/Sj.Leu.2404620  0.271
2012 Kikinis Z, Asami T, Bouix S, Finn CT, Ballinger T, Tworog-Dube E, Kucherlapati R, Kikinis R, Shenton ME, Kubicki M. Reduced fractional anisotropy and axial diffusivity in white matter in 22q11.2 deletion syndrome: a pilot study. Schizophrenia Research. 141: 35-9. PMID 22863550 DOI: 10.1016/J.Schres.2012.06.032  0.27
2014 Prendiville TW, Gauvreau K, Tworog-Dube E, Patkin L, Kucherlapati RS, Roberts AE, Lacro RV. Cardiovascular disease in Noonan syndrome. Archives of Disease in Childhood. 99: 629-34. PMID 24534818 DOI: 10.1136/Archdischild-2013-305047  0.27
2015 Yurgelun MB, Masciari S, Joshi VA, Mercado RC, Lindor NM, Gallinger S, Hopper JL, Jenkins MA, Buchanan DD, Newcomb PA, Potter JD, Haile RW, Kucherlapati R, Syngal S. Germline TP53 Mutations in Patients With Early-Onset Colorectal Cancer in the Colon Cancer Family Registry. Jama Oncology. 1: 214-21. PMID 26086041 DOI: 10.1001/Jamaoncol.2015.0197  0.268
2013 Kikinis Z, Makris N, Finn CT, Bouix S, Lucia D, Coleman MJ, Tworog-Dube E, Kikinis R, Kucherlapati R, Shenton ME, Kubicki M. Genetic contributions to changes of fiber tracts of ventral visual stream in 22q11.2 deletion syndrome. Brain Imaging and Behavior. 7: 316-25. PMID 23612843 DOI: 10.1007/S11682-013-9232-5  0.268
2003 Takahashi C, Bronson RT, Socolovsky M, Contreras B, Lee KY, Jacks T, Noda M, Kucherlapati R, Ewen ME. Rb and N-ras function together to control differentiation in the mouse. Molecular and Cellular Biology. 23: 5256-68. PMID 12861012 DOI: 10.1128/Mcb.23.15.5256-5268.2003  0.267
2006 Klein J, Ju W, Heyer J, Wittek B, Haneke T, Knaus P, Kucherlapati R, Böttinger EP, Nitschke L, Kneitz B. B cell-specific deficiency for Smad2 in vivo leads to defects in TGF-beta-directed IgA switching and changes in B cell fate. Journal of Immunology (Baltimore, Md. : 1950). 176: 2389-96. PMID 16455997 DOI: 10.4049/Jimmunol.176.4.2389  0.266
2013 Li C, Li A, Xing Y, Li M, Chan B, Ouyang R, Taketo MM, Kucherlapati R, Borok Z, Minoo P. Apc deficiency alters pulmonary epithelial cell fate and inhibits Nkx2.1 via triggering TGF-beta signaling. Developmental Biology. 378: 13-24. PMID 23562608 DOI: 10.1016/J.Ydbio.2013.03.018  0.266
1997 Kucherlapati R, Marynen P, Turc-Carel C. Report of the fourth International Workshop in Human Chromosome 12 Mapping, 1997. Cytogenetics and Cell Genetics. 78: 82-95. PMID 9371396  0.266
2009 Wang XP, O'Connell DJ, Lund JJ, Saadi I, Kuraguchi M, Turbe-Doan A, Cavallesco R, Kim H, Park PJ, Harada H, Kucherlapati R, Maas RL. Apc inhibition of Wnt signaling regulates supernumerary tooth formation during embryogenesis and throughout adulthood. Development (Cambridge, England). 136: 1939-49. PMID 19429790 DOI: 10.1242/Dev.033803  0.265
1992 Craig I, Gemmill R, Kucherlapati R. Report of the first international workshop on human chromosome 12 mapping. Cytogenetics and Cell Genetics. 61: 243-51. PMID 1362534  0.265
2011 McIlhatton MA, Tyler J, Kerepesi LA, Bocker-Edmonston T, Kucherlapati MH, Edelmann W, Kucherlapati R, Kopelovich L, Fishel R. Aspirin and low-dose nitric oxide-donating aspirin increase life span in a Lynch syndrome mouse model. Cancer Prevention Research (Philadelphia, Pa.). 4: 684-93. PMID 21436383 DOI: 10.1158/1940-6207.Capr-10-0319  0.264
2007 Sequist LV, Joshi VA, Jänne PA, Muzikansky A, Fidias P, Meyerson M, Haber DA, Kucherlapati R, Johnson BE, Lynch TJ. Response to treatment and survival of patients with non-small cell lung cancer undergoing somatic EGFR mutation testing. The Oncologist. 12: 90-8. PMID 17285735 DOI: 10.1634/Theoncologist.12-1-90  0.264
1984 Kucherlapati R, Skoultchi AI. Introduction of purified genes into mammalian cells. Crc Critical Reviews in Biochemistry. 16: 349-79. PMID 6094097 DOI: 10.3109/10409238409108719  0.264
1995 Sirotkin AM, Edelmann W, Cheng G, Klein-Szanto A, Kucherlapati R, Skoultchi AI. Mice develop normally without the H1(0) linker histone. Proceedings of the National Academy of Sciences of the United States of America. 92: 6434-8. PMID 7604008 DOI: 10.1073/Pnas.92.14.6434  0.262
2013 Hoshino S, Sakamoto K, Vassilopoulos S, Camus SM, Griffin CA, Esk C, Torres JA, Ohkoshi N, Ishii A, Tamaoka A, Funke BH, Kucherlapati R, Margeta M, Rando TA, Brodsky FM. The CHC22 clathrin-GLUT4 transport pathway contributes to skeletal muscle regeneration. Plos One. 8: e77787. PMID 24204966 DOI: 10.1371/Journal.Pone.0077787  0.261
1989 Campbell CR, Ayares D, Watkins K, Wolski R, Kucherlapati R. Single-stranded DNA gaps, tails and loops are repaired in Escherichia coli. Mutation Research. 211: 181-8. PMID 2646531 DOI: 10.1016/0027-5107(89)90118-8  0.261
2014 Brennan C, Verhaak R, McKenna A, Campos B, Noushmehr H, Salama S, Zheng S, Chakravarty D, Sanborn J, Berman S, Beroukhim R, Bernard B, Wu C, Genovese G, Shmulevich I, ... ... Kucherlapati R, et al. The Somatic Genomic Landscape of Glioblastoma Cell. 157: 753. DOI: 10.1016/J.Cell.2014.04.004  0.259
2009 Hung K, Richard LG, Mahmood U, Kucherlapati R. S1996 A New Preclinical Mouse Model for Sporadic Primary and Metastatic Colon Cancer Gastroenterology. 136: A-309. DOI: 10.1016/S0016-5085(09)61412-8  0.259
2006 Hagendoorn J, Tong R, Fukumura D, Lin Q, Lobo J, Padera TP, Xu L, Kucherlapati R, Jain RK. Onset of abnormal blood and lymphatic vessel function and interstitial hypertension in early stages of carcinogenesis. Cancer Research. 66: 3360-4. PMID 16585153 DOI: 10.1158/0008-5472.Can-05-2655  0.257
1994 Kucherlapati R, Craig I, Marynen P. Report and abstracts of the Second International Workshop on Human Chromosome 12 mapping 1994. New Haven, Connecticut, June 20-22, 1994. Cytogenetics and Cell Genetics. 67: 245-76. PMID 7924453  0.256
2008 Hung K, Georgeon Richard L, Kunin A, Mahmood U, Kucherlapati R. S2054 A Novel Mouse Model of Sporadic Colorectal Cancer Gastroenterology. 134: A-305-A-306. DOI: 10.1016/S0016-5085(08)61424-9  0.256
2011 Taguchi A, Politi K, Pitteri SJ, Lockwood WW, Faça VM, Kelly-Spratt K, Wong CH, Zhang Q, Chin A, Park KS, Goodman G, Gazdar AF, Sage J, Dinulescu DM, Kucherlapati R, et al. Lung cancer signatures in plasma based on proteome profiling of mouse tumor models. Cancer Cell. 20: 289-99. PMID 21907921 DOI: 10.1016/J.Ccr.2011.08.007  0.256
2006 Ju W, Ogawa A, Heyer J, Nierhof D, Yu L, Kucherlapati R, Shafritz DA, Böttinger EP. Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation. Molecular and Cellular Biology. 26: 654-67. PMID 16382155 DOI: 10.1128/Mcb.26.2.654-667.2006  0.254
2005 Zervas M, Opitz T, Edelmann W, Wainer B, Kucherlapati R, Stanton PK. Impaired hippocampal long-term potentiation in microtubule-associated protein 1B-deficient mice. Journal of Neuroscience Research. 82: 83-92. PMID 16118800 DOI: 10.1002/Jnr.20624  0.252
2014 Turker NS, Heidari P, Kucherlapati R, Kucherlapati M, Mahmood U. An EGFR targeted PET imaging probe for the detection of colonic adenocarcinomas in the setting of colitis. Theranostics. 4: 893-903. PMID 25057314 DOI: 10.7150/Thno.9425  0.251
2009 Vassilopoulos S, Esk C, Hoshino S, Funke BH, Chen CY, Plocik AM, Wright WE, Kucherlapati R, Brodsky FM. A role for the CHC22 clathrin heavy-chain isoform in human glucose metabolism. Science (New York, N.Y.). 324: 1192-6. PMID 19478182 DOI: 10.1126/Science.1171529  0.251
2012 Smpokou P, Tworog-Dube E, Kucherlapati RS, Roberts AE. Medical complications, clinical findings, and educational outcomes in adults with Noonan syndrome. American Journal of Medical Genetics. Part A. 158: 3106-11. PMID 23165751 DOI: 10.1002/Ajmg.A.35639  0.251
2008 Zhang Q, Menon R, Deutsch EW, Pitteri SJ, Faca VM, Wang H, Newcomb LF, Depinho RA, Bardeesy N, Dinulescu D, Hung KE, Kucherlapati R, Jacks T, Politi K, Aebersold R, et al. A mouse plasma peptide atlas as a resource for disease proteomics. Genome Biology. 9: R93. PMID 18522751 DOI: 10.1186/Gb-2008-9-6-R93  0.25
2005 Sequist L, Janne P, Joshi V, Fidias P, Verlander P, Meyerson M, Haber D, Johnson B, Kucherlapati R, Lynch T. PD-156 The Massachusetts General Hospital/Dana-Farber Cancer Institute/Harvard Medical School Partners HealthCare Center for genetics and genomics experience with clinical testing for somatic EGFR mutations in NSCLC patients Lung Cancer. 49: S112. DOI: 10.1016/S0169-5002(05)80489-1  0.249
1990 Keown WA, Campbell CR, Kucherlapati RS. Methods for introducing DNA into mammalian cells. Methods in Enzymology. 185: 527-37. PMID 2381329 DOI: 10.1016/0076-6879(90)85043-N  0.247
2009 Luong MX, Tam J, Lin Q, Hagendoorn J, Moore KJ, Padera TP, Seed B, Fukumura D, Kucherlapati R, Jain RK. Lack of lymphatic vessel phenotype in LYVE-1/CD44 double knockout mice. Journal of Cellular Physiology. 219: 430-7. PMID 19170073 DOI: 10.1002/Jcp.21686  0.247
2000 Edelmann W, Umar A, Yang K, Heyer J, Kucherlapati M, Lia M, Kneitz B, Avdievich E, Fan K, Wong E, Crouse G, Kunkel T, Lipkin M, Kolodner RD, Kucherlapati R. The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression. Cancer Research. 60: 803-7. PMID 10706084  0.245
2005 Owen BA, Yang Z, Lai M, Gajec M, Gajek M, Badger JD, Hayes JJ, Edelmann W, Kucherlapati R, Wilson TM, McMurray CT. (CAG)(n)-hairpin DNA binds to Msh2-Msh3 and changes properties of mismatch recognition. Nature Structural & Molecular Biology. 12: 663-70. PMID 16025128 DOI: 10.1038/Nsmb965  0.245
2012 Ladd JJ, Busald T, Johnson MM, Zhang Q, Pitteri SJ, Wang H, Brenner DE, Lampe PD, Kucherlapati R, Feng Z, Prentice RL, Hanash SM. Increased plasma levels of the APC-interacting protein MAPRE1, LRG1, and IGFBP2 preceding a diagnosis of colorectal cancer in women. Cancer Prevention Research (Philadelphia, Pa.). 5: 655-64. PMID 22277732 DOI: 10.1158/1940-6207.Capr-11-0412  0.244
2010 Masciari S, Joshi VA, Mercado R, Walsh JL, Lindor NM, Gallinger S, Hopper J, Potter JD, Haile RW, Kucherlapati R, Syngal S. 1032 Prevalence of Germline TP53 Mutations in 510 Population and Clinic-Based Cases of Colorectal Cancer Diagnosed Under Age 40 Gastroenterology. 138: S-150-S-151. DOI: 10.1016/S0016-5085(10)60691-9  0.242
2014 Turker NS, Mahmood U, Kucherlapati MH, Kucherlapati R. Abstract 4926: Molecular imaging of colorectal cancer in the setting of colitis Cancer Research. 74: 4926-4926. DOI: 10.1158/1538-7445.Am2014-4926  0.241
1996 Liedtke W, Edelmann W, Bieri PL, Chiu FC, Cowan NJ, Kucherlapati R, Raine CS. GFAP is necessary for the integrity of CNS white matter architecture and long-term maintenance of myelination. Neuron. 17: 607-15. PMID 8893019 DOI: 10.1016/S0896-6273(00)80194-4  0.239
2004 Funke B, Finn CT, Plocik AM, Lake S, DeRosse P, Kane JM, Kucherlapati R, Malhotra AK. Association of the DTNBP1 locus with schizophrenia in a U.S. population. American Journal of Human Genetics. 75: 891-8. PMID 15362017 DOI: 10.1086/425279  0.238
2012 Sheth RA, Kunin A, Stangenberg L, Sinnamon M, Hung KE, Kucherlapati R, Mahmood U. In vivo optical molecular imaging of matrix metalloproteinase activity following celecoxib therapy for colorectal cancer. Molecular Imaging. 11: 417-25. PMID 22954186 DOI: 10.2310/7290.2012.00003  0.237
1999 Cheung VG, Morley M, Aguilar F, Massimi A, Kucherlapati R, Childs G. Making and reading microarrays. Nature Genetics. 21: 15-9. PMID 9915495 DOI: 10.1038/4439  0.236
2011 Liao S, Cheng G, Conner DA, Huang Y, Kucherlapati RS, Munn LL, Ruddle NH, Jain RK, Fukumura D, Padera TP. Impaired lymphatic contraction associated with immunosuppression. Proceedings of the National Academy of Sciences of the United States of America. 108: 18784-9. PMID 22065738 DOI: 10.1073/Pnas.1116152108  0.236
2015 Taguchi A, Rho JH, Yan Q, Zhang Y, Zhao Y, Xu H, Tripathi SC, Wang H, Brenner D, Kucherlapati M, Kucherlapati RS, Boutin A, Wang YA, DePinho RA, Feng Z, et al. MAPRE1 as a plasma biomarker for early-stage colorectal cancer and adenomas. Cancer Prevention Research (Philadelphia, Pa.). PMID 26342024 DOI: 10.1158/1940-6207.Capr-15-0077  0.235
2009 Narr KL, Szeszko PR, Lencz T, Woods RP, Hamilton LS, Phillips O, Robinson D, Burdick KE, DeRosse P, Kucherlapati R, Thompson PM, Toga AW, Malhotra AK, Bilder RM. DTNBP1 is associated with imaging phenotypes in schizophrenia. Human Brain Mapping. 30: 3783-94. PMID 19449336 DOI: 10.1002/Hbm.20806  0.235
2001 Jenkins NA, Kucherlapati RS, McKusick VA. Reflecting the bright future of genomics Genomics. 75: 1-2. DOI: 10.1006/Geno.2001.6597  0.235
2001 Piek E, Ju WJ, Heyer J, Escalante-Alcalde D, Stewart CL, Weinstein M, Deng C, Kucherlapati R, Bottinger EP, Roberts AB. Functional characterization of transforming growth factor beta signaling in Smad2- and Smad3-deficient fibroblasts. The Journal of Biological Chemistry. 276: 19945-53. PMID 11262418 DOI: 10.1074/Jbc.M102382200  0.234
2010 Kim P, Chung E, Yamashita H, Hung KE, Mizoguchi A, Kucherlapati R, Fukumura D, Jain RK, Yun SH. In vivo wide-area cellular imaging by side-view endomicroscopy. Nature Methods. 7: 303-5. PMID 20228814 DOI: 10.1038/Nmeth.1440  0.234
2006 Sequist LV, Joshi VA, Jänne PA, Fidias P, Muzikansky A, Meyerson M, Haber DA, Kucherlapati R, Johnson BE, Lynch TJ. Epidermal growth factor receptor (EGFR) mutation testing in non-small cell lung cancer (NSCLC) patients (pts) Journal of Clinical Oncology. 24: 7177-7177. DOI: 10.1200/Jco.2006.24.18_Suppl.7177  0.233
1999 Mahmoud NN, Bilinski RT, Churchill MR, Edelmann W, Kucherlapati R, Bertagnolli MM. Genotype-phenotype correlation in murine Apc mutation: differences in enterocyte migration and response to sulindac. Cancer Research. 59: 353-9. PMID 9927046  0.23
1989 Campbell CR, Keown W, Lowe L, Kirschling D, Kucherlapati R. Homologous recombination involving small single-stranded oligonucleotides in human cells. The New Biologist. 1: 223-7. PMID 2562222  0.229
2022 Li J, Lu H, Ng PK, Pantazi A, Ip CKM, Jeong KJ, Amador B, Tran R, Tsang YH, Yang L, Song X, Dogruluk T, Ren X, Hadjipanayis A, Bristow CA, ... ... Kucherlapati R, et al. A functional genomic approach to actionable gene fusions for precision oncology. Science Advances. 8: eabm2382. PMID 35138907 DOI: 10.1126/sciadv.abm2382  0.228
2005 Funke B, Malhotra AK, Finn CT, Plocik AM, Lake SL, Lencz T, DeRosse P, Kane JM, Kucherlapati R. COMT genetic variation confers risk for psychotic and affective disorders: a case control study. Behavioral and Brain Functions : Bbf. 1: 19. PMID 16232322 DOI: 10.1186/1744-9081-1-19  0.228
2010 Kim P, Chung E, Yamashita H, Hung KE, Mizoguchi A, Kucherlapati R, Fukumura D, Jain RK, Yun SH. In Vivo Fluorescence Cellular Imaging by Side-view Endomicroscopy Ieee Transactions On Biomedical Engineering. DOI: 10.1364/Biomed.2010.Bmd3  0.226
1976 Kucherlapati RS, Ruddle FH. Advances in human gene mapping by parasexual procedures. Progress in Medical Genetics. 1: 121-44. PMID 778918  0.225
1976 Anderson WF, Deisseroth AB, Velez R, Nienhuis AW, Ruddle FH, Kucherlapati RS. A new technique for mapping the human hemoglobin genes. Birth Defects Original Article Series. 12: 367-71. PMID 799520  0.22
2007 Joshi VA, Kucherlapati R. Pharmacogenomics of lung cancer: with a view to address EGFR-targeted therapies. Pharmacogenomics. 8: 1211-20. PMID 17924836 DOI: 10.2217/14622416.8.9.1211  0.22
1994 Munro C, Carter S, Bryce S, Stevenson A, Healy E, Nagy G, Jacyk W, Kucherlapati R, Rees J, Strachan T. A single locus for Darier's disease in families of diverse European origin Journal of Investigative Dermatology. 103: 428. DOI: 10.5555/Uri:Pii:0022202X9492368X  0.218
2009 Joshi VA, Duffy E, Funke BH, Farwell LM, Mancini-Dinardo D, Kucherlapati R. Platform evaluation for rapid genotyping of CYP2C9 and VKORC1 alleles. Personalized Medicine. 6: 449-457. PMID 29783542 DOI: 10.2217/Pme.09.8  0.217
2005 Dziejman M, Serruto D, Tam VC, Sturtevant D, Diraphat P, Faruque SM, Rahman MH, Heidelberg JF, Decker J, Li L, Montgomery KT, Grills G, Kucherlapati R, Mekalanos JJ. Genomic characterization of non-O1, non-O139 Vibrio cholerae reveals genes for a type III secretion system. Proceedings of the National Academy of Sciences of the United States of America. 102: 3465-70. PMID 15728357 DOI: 10.1073/Pnas.0409918102  0.216
2006 DeRosse P, Funke B, Burdick KE, Lencz T, Ekholm JM, Kane JM, Kucherlapati R, Malhotra AK. Dysbindin genotype and negative symptoms in schizophrenia. The American Journal of Psychiatry. 163: 532-4. PMID 16513878 DOI: 10.1176/Appi.Ajp.163.3.532  0.216
2007 Burdick KE, Goldberg TE, Funke B, Bates JA, Lencz T, Kucherlapati R, Malhotra AK. DTNBP1 genotype influences cognitive decline in schizophrenia. Schizophrenia Research. 89: 169-72. PMID 17074466 DOI: 10.1016/J.Schres.2006.09.008  0.214
1986 KUCHERLAPATI R. Molecular cell genetics Edited by M. M. Gottesman. New York: John Wiley & Sons. (1985). 931 pp. $dollar;79.95 Cell. 45: 328. DOI: 10.1016/0092-8674(86)90317-X  0.213
2006 DeRosse P, Funke B, Burdick KE, Lencz T, Goldberg TE, Kane JM, Kucherlapati R, Malhotra AK. COMT genotype and manic symptoms in schizophrenia. Schizophrenia Research. 87: 28-31. PMID 16828262 DOI: 10.1016/J.Schres.2006.06.008  0.213
2011 Kucherlapati R. Introduction for: frontiers of personalized cancer medicine. Cancer Journal (Sudbury, Mass.). 17: 403-4. PMID 22157283 DOI: 10.1097/Ppo.0B013E31823E7006  0.207
2009 Lakdawala NK, Baxter S, Duffy E, Kucherlapati R, Seidman JG, Seidman CE, Ho CY, Funke B. Sarcomeric Dilated Cardiomyopathy: Onset from Infancy to Late Adulthood Journal of Cardiac Failure. 15. DOI: 10.1016/J.Cardfail.2009.06.302  0.204
2005 Owen BAL, Yang Z, Lai M, Gajek M, Badger JD, Hayes JJ, Edelmann W, Kucherlapati R, Wilson TM, McMurray CT. Correction: Corrigendum: (CAG)n-hairpin DNA binds to Msh2–Msh3 and changes properties of mismatch recognition Nature Structural & Molecular Biology. 12: 824-824. DOI: 10.1038/Nsmb0905-824A  0.203
2012 Perlstein TS, Goldhaber SZ, Nelson K, Joshi V, Morgan TV, Lesko LJ, Lee JY, Gobburu J, Schoenfeld D, Kucherlapati R, Freeman MW, Creager MA. The Creating an Optimal Warfarin Nomogram (CROWN) Study. Thrombosis and Haemostasis. 107: 59-68. PMID 22116191 DOI: 10.1160/Th11-08-0568  0.203
2014 Babykutty S, Heishi T, Tsukada K, Huang Y, Kozin S, Conner D, Lin Q, Kucherlapati R, Jain RK, Fukumura D. Restoring perivascular nitric oxide gradients normalizes breast cancer vasculature Nitric Oxide. 42: 115. DOI: 10.1016/J.Niox.2014.09.051  0.201
2008 Wang X, O'Connell D, Lund JJ, Saadi I, Kuraguchi M, Turbe-Doan A, Kucherlapati R, Maas RL. APC inhibits supernumerary tooth formation during embryogenesis and throughout adulthood Developmental Biology. 319: 480. DOI: 10.1016/J.Ydbio.2008.05.054  0.196
2002 Fritz B, Schubert F, Wrobel G, Schwaenen C, Wessendorf S, Nessling M, Korz C, Rieker RJ, Montgomery K, Kucherlapati R, Mechtersheimer G, Eils R, Joos S, Lichter P. Microarray-based copy number and expression profiling in dedifferentiated and pleomorphic liposarcoma. Cancer Research. 62: 2993-8. PMID 12036902  0.196
1999 Yang R, Zhang A, Massimi A, Harris TM, Kneitz S, Childs G, Kucherlapati R. MAT a set of microarray data management and analysis tools Nature Genetics. 23: 84-84. DOI: 10.1038/14432  0.195
2001 Hörig H, Wainstein A, Long L, Kahn D, Soni S, Marcus A, Edelmann W, Kucherlapati R, Kaufman HL. A new mouse model for evaluating the immunotherapy of human colorectal cancer. Cancer Research. 61: 8520-6. PMID 11731437  0.192
1997 Carlson C, Papolos D, Pandita RK, Faedda GL, Veit S, Goldberg R, Shprintzen R, Kucherlapati R, Morrow B. Molecular analysis of velo-cardio-facial syndrome patients with psychiatric disorders. American Journal of Human Genetics. 60: 851-9. PMID 9106531  0.192
2001 Kuraguchi M, Yang K, Wong E, Avdievich E, Fan K, Kolodner RD, Lipkin M, Brown AM, Kucherlapati R, Edelmann W. The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis. Cancer Research. 61: 7934-42. PMID 11691815  0.19
1976 Schacter B, Kucherlapati RS, Ruddle FH. Synteny of the loci for beta2-microglobulin and PKM2 in man-mouse somatic cell hybrid subclones. Birth Defects Original Article Series. 12: 215-8. PMID 66943  0.188
1985 Ayares D, Spencer J, Schwartz F, Morse B, Kucherlapati R. Homologous recombination between autonomously replicating plasmids in mammalian cells. Genetics. 111: 375-88. PMID 2996980  0.187
2001 Yang WC, Mathew J, Velcich A, Edelmann W, Kucherlapati R, Lipkin M, Yang K, Augenlicht LH. Targeted inactivation of the p21(WAF1/cip1) gene enhances Apc-initiated tumor formation and the tumor-promoting activity of a Western-style high-risk diet by altering cell maturation in the intestinal mucosal. Cancer Research. 61: 565-9. PMID 11212250  0.186
1999 Augenlicht LH, Anthony GM, Church TL, Edelmann W, Kucherlapati R, Yang K, Lipkin M, Heerdt BG. Short-chain fatty acid metabolism, apoptosis, and Apc-initiated tumorigenesis in the mouse gastrointestinal mucosa. Cancer Research. 59: 6005-9. PMID 10606249  0.182
2001 Yang W, Velcich A, Mariadason J, Nicholas C, Corner G, Houston M, Edelmann W, Kucherlapati R, Holt PR, Augenlicht LH. p21(WAF1/cip1) is an important determinant of intestinal cell response to sulindac in vitro and in vivo. Cancer Research. 61: 6297-302. PMID 11507085  0.175
1994 Poustka AM, Schlessinger D, Affara NA, Lau Y-C, Spurr NK, Kruse T, Naylor S, Kucherlapati R, Craig I, Marynen P, Scambler PJ. Subject Index, Vol. 67, 1994 Cytogenetic and Genome Research. 67: 404-404. DOI: 10.1159/000133874  0.175
1992 Lee K, Shiomi T, Schultz RA, Cohen MM, Matsuda Y, Harada Y-, Natsuume-Sakai S, Levy HP, Mattick JS, Hirning-Folz U, Winking H, Hameister H, Koleva M, Benova D, Dutrillaux B, ... ... Kucherlapati R, et al. Subject Index Vol. 61, 1992 Cytogenetic and Genome Research. 61: 300-300. DOI: 10.1159/000133429  0.175
2017 Kucherlapati R. Oliver Smithies (1925-2017). Nature. 542: 166. PMID 28179651 DOI: 10.1038/542166A  0.175
1994 Poustka AM, Schlessinger D, Affara NA, Lau Y-C, Spurr NK, Kruse T, Naylor S, Kucherlapati R, Craig I, Marynen P, Scambler PJ. Contents, Vol. 67, 1994 Cytogenetic and Genome Research. 67. DOI: 10.1159/000133856  0.167
1992 Lee K, Shiomi T, Schultz RA, Cohen MM, Matsuda Y, Harada Y-, Natsuume-Sakai S, Levy HP, Mattick JS, Hirning-Folz U, Winking H, Hameister H, Koleva M, Benova D, Dutrillaux B, ... ... Kucherlapati R, et al. Contents, Vol. 61, 1992 Cytogenetic and Genome Research. 61. DOI: 10.1159/000133414  0.167
2000 Marcus DM, Rustgi AK, Defoe D, Kucherlapati R, Edelmann W, Hamasaki D, Liou GI, Smith SB. Ultrastructural and ERG findings in mice with adenomatous polyposis coli gene disruption. Molecular Vision. 6: 169-77. PMID 10982921  0.166
1997 Basson CT, Bachinsky DR, Lin RC, Levi T, Elkins JA, Soults J, Grayzel D, Kroumpouzou E, Traill TA, Leblanc-Straceski J, Renault B, Kucherlapati R, Seidman J, Seidman CE. Erratum: Mutations in human TBX5 cause limb and cardiac malformation in Holt-Oram syndrome Nature Genetics. 15: 411-411. DOI: 10.1038/ng0497-411c  0.166
1976 McDogall JK, Gallimore PH, Dunn AR, Webb TP, Kucherlapati RS, Nichols EA, Ruddle FH. Mapping viral integation sites in somatic cell hybrids. Birth Defects Original Article Series. 12: 206-10. PMID 192366  0.154
2003 Shinozaki H, Yang K, Fan K, Edelmann W, Kucherlapati R, Weinstein IB, Lipkin M. Cyclin D1 expression in the intestinal mucosa and tumors of Apc1638N mice. Anticancer Research. 23: 2217-26. PMID 12894495  0.154
1997 Sato Y, Bohlander SK, Kobayashi H, Reshmi S, Suto Y, Davis EM, Espinosa R, Hoopes R, Montgomery KT, Kucherlapati RS, Le Beau MM, Rowley JD. Heterogeneity in the breakpoints in balanced rearrangements involving band 12p13 in hematologic malignancies identified by fluorescence in situ hybridization: TEL (ETV6 ) is involved in only one half. Blood. 90: 4886-93. PMID 9389705  0.138
1999 Lipkin M, Yang K, Edelmann W, Xue L, Fan K, Risio M, Newmark H, Kucherlapati R. Preclinical mouse models for cancer chemoprevention studies. Annals of the New York Academy of Sciences. 889: 14-9. PMID 10668478 DOI: 10.1111/J.1749-6632.1999.Tb08719.X  0.136
1998 Yang K, Edelmann W, Fan K, Lau K, Leung D, Newmark H, Kucherlapati R, Lipkin M. Dietary modulation of carcinoma development in a mouse model for human familial adenomatous polyposis. Cancer Research. 58: 5713-7. PMID 9865728  0.132
1995 Miller PL, Nadkarni PM, Kucherlapati R, Krauter KS, Kidd KK, Ward DC, Shepherd GM, Berkowicz D. Network-based informatics support of research collaborations in the Human Genome Project and the Human Brain Project. Medinfo. Medinfo. 8: 1541-4. PMID 8591495  0.13
1996 Liedtke W, Edelmann W, Kucherlapati R, Raine CS. THE NEUROPATHOLOGIC PHENOTYPE OF GFAP DEFICIENT MICE Journal of Neuropathology and Experimental Neurology. 55: 620. DOI: 10.1097/00005072-199605000-00071  0.123
2019 Esfahani SA, Heidari P, Kucherlapati MH, Ferrer JM, Kucherlapati RS, Mahmood U. Optical imaging with a novel cathepsin-activatable probe for enhanced detection of colorectal cancer. American Journal of Nuclear Medicine and Molecular Imaging. 9: 230-242. PMID 31772821  0.118
2001 Saint-Jore B, Koskas F, Kucherlapati R, Chapman J, Thillet J. Large-scale gene expression analysis of lipid core-loaded macrophages reveals upregulation of transcription factors Atherosclerosis Supplements. 2: 37. DOI: 10.1016/S1567-5688(01)80022-2  0.116
1990 Camerini-Otero RD, Kucherlapati R. Right on target. Applications of Homologous Recombination to Human Disease sponsored by the National Institutes of Health (NIGMS, NIDDK, and NICHD) Bethesda, MD, USA, November 6-8, 1989. The New Biologist. 2: 337-41. PMID 2288907  0.114
1999 Edelmann W, Yang K, Kuraguchi M, Heyer J, Lia M, Kneitz B, Fan K, Brown AM, Lipkin M, Kucherlapati R. Tumorigenesis in Mlh1 and Mlh1/Apc1638N mutant mice. Cancer Research. 59: 1301-7. PMID 10096563  0.114
2000 Vaughan CJ, Casey M, He J, Hatcher C, Winter JM, Weremowicz S, Montgomery K, Kucherlapati R, Morton CC, Basson CT. Mutations in the R1α Regulatory Subunit of Protein Kinase A Cause Familial Cardiac Myxomas Circulation. 102: 2672-2672. DOI: 10.1161/01.CIR.102.21.2672-H  0.106
2007 Kochilas L, Liao J, Merscher-Gomez S, Kucherlapati R, Morrow B, Epstein JA. New Insights into the Role of Tbx1 in the Digeorge Mouse Model Cardiovascular Development and Congenital Malformations: Molecular & Genetic Mechanisms. 135-136. DOI: 10.1002/9780470988664.ch34  0.105
1998 Liedtke W, Edelmann W, Chiu FC, Kucherlapati R, Raine CS. Experimental autoimmune encephalomyelitis in mice lacking glial fibrillary acidic protein is characterized by a more severe clinical course and an infiltrative central nervous system lesion. The American Journal of Pathology. 152: 251-9. PMID 9422542  0.097
1997 Fox JG, Dangler CA, Whary MT, Edelman W, Kucherlapati R, Wang TC. Mice carrying a truncated Apc gene have diminished gastric epithelial proliferation, gastric inflammation, and humoral immunity in response to Helicobacter felis infection. Cancer Research. 57: 3972-8. PMID 9307281  0.093
1994 Chan YM, Yu QC, LeBlanc-Straceski J, Christiano A, Pulkkinen L, Kucherlapati RS, Uitto J, Fuchs E. Mutations in the non-helical linker segment L1-2 of keratin 5 in patients with Weber-Cockayne epidermolysis bullosa simplex. Journal of Cell Science. 107: 765-74. PMID 7520042  0.093
2014 Kucherlapati R. Genomics and Proteomics Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.05477-5  0.082
2010 Kucherlapati R. Personalized medicine for non-small-cell lung cancer. Oncology (Williston Park, N.Y.). 24: 399-400. PMID 20480736  0.074
2010 Kucherlapati R, Cabot PC. Personalized medicine for nonsmall-cell lung cancer Oncology. 24.  0.07
2009 Joshi VA, Duffy E, Funke BH, Farwell LM, Mancini-Dinardo D, Kucherlapati R. Platform evaluation for rapid genotyping of CYP2C9 and VKORC1 alleles Personalized Medicine. 6: 449-457. DOI: 10.2217/pme.09.8  0.052
1999 Edelmann L, Funke B, Pandita RK, Puech A, Saint-Lore B, Goldberg R, Shprintzen R, Kucherlapati R, Skoultch A, Morrow BE. Efforts to determine the molecular basis of VCFS Genetic Counseling. 10: 106.  0.034
2006 Kucherlapati R, Cabot PC. Who will lead the revolution? Genetic Engineering News. 26: 6-8.  0.032
2009 Joshi VA, Roberts AE, Kucherlapati R. Towards a treatment for RAS-MAPK pathway disorders Monographs in Human Genetics. 17: 151-164. DOI: 10.1159/000164851  0.03
2007 Kucherlapati R. Raju Kucherlapati talks about personalised medicine: breathing new life into old drugs. Interview by Steve Carney. Drug Discovery Today. 12: 272-5. PMID 17458021 DOI: 10.1016/j.drudis.2007.02.008  0.014
2011 Farooq F, Krishnapuram B, Rosales R, Yu S, Shavlik J, Kucherlapati R. Predictive Models in Personalized Medicine Acm Sighit Record. 1: 23-25. DOI: 10.1145/1971706.1971714  0.012
2023 Kucherlapati R. Impact of Precision Medicine in Oncology. Cancer Journal (Sudbury, Mass.). 29: 1-2. PMID 36693150 DOI: 10.1097/PPO.0000000000000642  0.01
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