| Year |
Citation |
Score |
| 2023 |
Jailkhani N, Clauser KR, Mak HH, Rickelt S, Tian C, Whittaker CA, Tanabe KK, Purdy SR, Carr SA, Hynes RO. Proteomic profiling of extracellular matrix components from patient metastases identifies consistently elevated proteins for developing nanobodies that target primary tumors and metastases. Cancer Research. PMID 37098922 DOI: 10.1158/0008-5472.CAN-22-1532 |
0.542 |
|
| 2021 |
Rickelt S, Neyaz A, Condon C, Whittaker CA, Zaidi AH, Taylor MS, Abbruzzese G, Mattia AR, Zukerberg L, Shroff SG, Yilmaz OH, Yılmaz O, Wu EY, Choi WT, Jobe BA, ... ... Hynes RO, et al. Agrin loss in Barrett's esophagus-related neoplasia and its utility as a diagnostic and predictive biomarker. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34785582 DOI: 10.1158/1078-0432.CCR-21-2822 |
0.499 |
|
| 2020 |
Benjamin DC, Kang JH, Hamza B, King EM, Lamar JM, Manalis SR, Hynes RO. YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Re-entry into Systemic Circulation. Cancer Research. PMID 32591412 DOI: 10.1158/0008-5472.Can-20-0212 |
0.328 |
|
| 2020 |
Hebert JD, Tian C, Lamar JM, Rickelt S, Abbruzzese G, Liu X, Hynes RO. The scaffold protein IQGAP1 is crucial for extravasation and metastasis. Scientific Reports. 10: 2439. PMID 32051509 DOI: 10.1038/S41598-020-59438-W |
0.351 |
|
| 2020 |
Tian C, Öhlund D, Rickelt S, Lidström T, Huang Y, Hao L, Zhao RT, Franklin O, Bhatia SN, Tuveson DA, Hynes RO. Cancer-cell-derived matrisome proteins promote metastasis in pancreatic ductal adenocarcinoma. Cancer Research. PMID 32029550 DOI: 10.1158/0008-5472.Can-19-2578 |
0.347 |
|
| 2020 |
Hebert JD, Myers SA, Naba A, Abbruzzese G, Lamar J, Carr SA, Hynes RO. Proteomic profiling of the ECM of xenograft breast cancer metastases in different organs reveals distinct metastatic niches. Cancer Research. PMID 32019869 DOI: 10.1158/0008-5472.Can-19-2961 |
0.341 |
|
| 2019 |
Tian C, Clauser KR, Öhlund D, Rickelt S, Huang Y, Gupta M, Mani DR, Carr SA, Tuveson DA, Hynes RO. Proteomic analyses of ECM during pancreatic ductal adenocarcinoma progression reveal different contributions by tumor and stromal cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 31484774 DOI: 10.1073/Pnas.1908626116 |
0.356 |
|
| 2018 |
Lamar JM, Xiao Y, Norton E, Jiang ZG, Gerhard GM, Kooner S, Warren JSA, Hynes RO. SRC tyrosine kinase activates the YAP/TAZ axis and thereby drives tumor growth and metastasis. The Journal of Biological Chemistry. PMID 30559289 DOI: 10.1074/Jbc.Ra118.004364 |
0.302 |
|
| 2018 |
Chen MB, Hajal C, Benjamin DC, Yu C, Azizgolshani H, Hynes RO, Kamm RD. Inflamed neutrophils sequestered at entrapped tumor cells via chemotactic confinement promote tumor cell extravasation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29915060 DOI: 10.1073/Pnas.1715932115 |
0.349 |
|
| 2018 |
Naba A, Clauser KR, Carr SA, Hynes RO. Abstract 5004: Profiling the extracellular matrix landscape of tumor microenvironments using proteomics Cancer Research. 78: 5004-5004. DOI: 10.1158/1538-7445.Am2018-5004 |
0.307 |
|
| 2017 |
Turner CJ, Badu-Nkansah K, Hynes RO. Endothelium-derived fibronectin regulates neonatal vascular morphogenesis in an autocrine fashion. Angiogenesis. PMID 28667352 DOI: 10.1007/S10456-017-9563-8 |
0.354 |
|
| 2017 |
Glavey SV, Naba A, Manier S, Clauser K, Tahri S, Park J, Reagan MR, Moschetta M, Mishima Y, Gambella M, Rocci A, Sacco A, O'Dwyer ME, Asara JM, Palumbo A, ... ... Hynes RO, et al. Proteomic characterization of human multiple myeloma bone marrow extracellular matrix. Leukemia. PMID 28344315 DOI: 10.1038/Leu.2017.102 |
0.32 |
|
| 2017 |
Ragelle H, Naba A, Larson BL, Zhou F, Prijić M, Whittaker CA, Del Rosario A, Langer R, Hynes RO, Anderson DG. Comprehensive proteomic characterization of stem cell-derived extracellular matrices. Biomaterials. 128: 147-159. PMID 28327460 DOI: 10.1016/J.Biomaterials.2017.03.008 |
0.612 |
|
| 2017 |
Zhu G, Zhang Q, Reddy EC, Carrim N, Chen Y, Xu XR, Xu M, Wang Y, Hou Y, Ma L, Li Y, Rui M, Petruzziello T, Lavalle C, Stratton TW, ... ... Hynes RO, et al. Integrin PSI domain has endogenous thiol isomerase function and is a novel target for anti-platelet therapy. Blood. PMID 28122739 DOI: 10.1182/Blood-2016-07-729400 |
0.331 |
|
| 2017 |
Naba A, Clauser KR, Mani DR, Carr SA, Hynes RO. Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression. Scientific Reports. 7: 40495. PMID 28071719 DOI: 10.1038/Srep40495 |
0.303 |
|
| 2016 |
Li R, Hebert JD, Lee TA, Xing H, Boussommier-Calleja A, Hynes RO, Lauffenburger DA, Kamm RD. Macrophage-secreted TNFα and TGFβ1 Influence Migration Speed and Persistence of Cancer Cells in 3D Tissue Culture via Independent Pathways. Cancer Research. PMID 27872091 DOI: 10.1158/0008-5472.Can-16-0442 |
0.331 |
|
| 2016 |
Carmona G, Perera U, Gillett C, Naba A, Law AL, Sharma VP, Wang J, Wyckoff J, Balsamo M, Mosis F, De Piano M, Monypenny J, Woodman N, McConnell RE, Mouneimne G, ... ... Hynes RO, et al. Lamellipodin promotes invasive 3D cancer cell migration via regulated interactions with Ena/VASP and SCAR/WAVE. Oncogene. PMID 26996666 DOI: 10.1038/Onc.2016.47 |
0.301 |
|
| 2016 |
Chen MB, Lamar JM, Li R, Hynes RO, Kamm RD. Elucidation of the roles of tumor integrin ß1 in the extravasation stage of the metastasis cascade. Cancer Research. PMID 26988988 DOI: 10.1158/0008-5472.Can-15-1325 |
0.348 |
|
| 2016 |
Oudin MJ, Jonas O, Kosciuk T, Broye LC, Guido BC, Wyckoff J, Riquelme D, Lamar JM, Asokan SB, Whittaker C, Ma D, Langer R, Cima MJ, Wisinski KB, Hynes RO, et al. Tumor cell-driven extracellular matrix remodeling enables haptotaxis during metastatic progression. Cancer Discovery. PMID 26811325 DOI: 10.1158/2159-8290.Cd-15-1183 |
0.325 |
|
| 2016 |
Oudin MJ, Jonas O, Kosciuk T, Broye L, Wyckoff J, Klazen J, Lamar J, Asokan S, Whittaker C, Langer R, Cima M, Wisinski K, Hynes R, Lauffenburger D, Keely P, et al. Abstract PR15: Haptotaxis and direct remodeling of the extracellular matrix by tumor cells is important for metastasis Cancer Research. 76. DOI: 10.1158/1538-7445.Tummet15-Pr15 |
0.359 |
|
| 2015 |
Shaw Bagnall J, Byun S, Begum S, Miyamoto DT, Hecht VC, Maheswaran S, Stott SL, Toner M, Hynes RO, Manalis SR. Deformability of Tumor Cells versus Blood Cells. Scientific Reports. 5: 18542. PMID 26679988 DOI: 10.1038/Srep18542 |
0.33 |
|
| 2015 |
Heilmann S, Ratnakumar K, Langdon E, Kansler E, Kim I, Campbell NR, Perry E, McMahon A, Kaufman C, van Rooijen E, Lee W, Iacobuzio-Donahue C, Hynes R, Zon L, Xavier J, et al. A quantitative system for studying metastasis using transparent zebrafish. Cancer Research. PMID 26282170 DOI: 10.1158/0008-5472.Can-14-3319 |
0.346 |
|
| 2015 |
Naba A, Clauser KR, Hynes RO. Enrichment of Extracellular Matrix Proteins from Tissues and Digestion into Peptides for Mass Spectrometry Analysis. Journal of Visualized Experiments : Jove. e53057. PMID 26273955 DOI: 10.3791/53057 |
0.32 |
|
| 2015 |
Naba A, Clauser KR, Ding H, Whittaker CA, Carr SA, Hynes RO. The extracellular matrix: Tools and insights for the "omics" era. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 26163349 DOI: 10.1016/J.Matbio.2015.06.003 |
0.575 |
|
| 2015 |
Murphy PA, Begum S, Hynes RO. Tumor angiogenesis in the absence of fibronectin or its cognate integrin receptors. Plos One. 10: e0120872. PMID 25807551 DOI: 10.1371/Journal.Pone.0120872 |
0.322 |
|
| 2015 |
Turner CJ, Badu-Nkansah K, Crowley D, van der Flier A, Hynes RO. α5 and αv integrins cooperate to regulate vascular smooth muscle and neural crest functions in vivo. Development (Cambridge, England). 142: 797-808. PMID 25670798 DOI: 10.1242/jcs.169722 |
0.306 |
|
| 2015 |
Tian C, Olund D, Tuveson D, Hynes RO. Abstract A45: Understanding the roles of extracellular matrix proteins in pancreatic ductal adenocarcinoma progression and metastasis Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-A45 |
0.318 |
|
| 2015 |
Chen MB, Lamar JM, Kamm RD, Hynes RO. Abstract 306: Role of tumor beta-1 integrin in the tumor cell extravasation cascade Cancer Research. 75: 306-306. DOI: 10.1158/1538-7445.Am2015-306 |
0.361 |
|
| 2015 |
Tian C, Ohlund D, Clauser K, Carr SA, Tuveson DA, Hynes RO. Abstract 1819: Profiling of extracellular matrix proteins in pancreatic ductal adenocarcinoma progression and metastasis Cancer Research. 75: 1819-1819. DOI: 10.1158/1538-7445.Am2015-1819 |
0.317 |
|
| 2014 |
Hynes RO. Stretching the boundaries of extracellular matrix research. Nature Reviews. Molecular Cell Biology. 15: 761-3. PMID 25574535 DOI: 10.1038/Nrm3908 |
0.328 |
|
| 2014 |
Naba A, Clauser KR, Whittaker CA, Carr SA, Tanabe KK, Hynes RO. Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver. Bmc Cancer. 14: 518. PMID 25037231 DOI: 10.1186/1471-2407-14-518 |
0.583 |
|
| 2014 |
Labelle M, Begum S, Hynes RO. Platelets guide the formation of early metastatic niches. Proceedings of the National Academy of Sciences of the United States of America. 111: E3053-61. PMID 25024172 DOI: 10.1073/Pnas.1411082111 |
0.369 |
|
| 2014 |
Murphy PA, Hynes RO. Alternative splicing of endothelial fibronectin is induced by disturbed hemodynamics and protects against hemorrhage of the vessel wall. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 2042-50. PMID 24903094 DOI: 10.1161/Atvbaha.114.303879 |
0.313 |
|
| 2014 |
Turner CJ, Badu-Nkansah K, Crowley D, van der Flier A, Hynes RO. Integrin-α5β1 is not required for mural cell functions during development of blood vessels but is required for lymphatic-blood vessel separation and lymphovenous valve formation. Developmental Biology. 392: 381-92. PMID 24858485 DOI: 10.1016/J.Ydbio.2014.05.006 |
0.353 |
|
| 2014 |
Naba A, Clauser KR, Lamar JM, Carr SA, Hynes RO. Extracellular matrix signatures of human mammary carcinoma identify novel metastasis promoters. Elife. 3: e01308. PMID 24618895 DOI: 10.7554/Elife.01308 |
0.313 |
|
| 2014 |
Glavey S, Naba A, Manier S, Gambella M, Rocci A, Sacco A, Asara JM, Moschetta M, Reagan MR, Mishima Y, Kawano Y, Roccaro AM, Palumbo A, Hynes RO, Ghobrial IM. Proteomic Characterization of the Multiple Myeloma Bone Marrow Extracellular Matrix Blood. 124: 2051-2051. DOI: 10.1182/Blood.V124.21.2051.2051 |
0.348 |
|
| 2014 |
Glavey SV, Naba A, Gambella M, Rocci A, Sacco A, Asara J, Palumbo A, Hynes RO, Roccaro AM, Ghobrial IM. Abstract 4855: Proteomic characterization of the extracellular matrix in multiple myeloma Cancer Research. 74: 4855-4855. DOI: 10.1158/1538-7445.Am2014-4855 |
0.349 |
|
| 2013 |
Yao X, Labelle M, Lamb CR, Dugan JM, Williamson CA, Spencer DR, Christ KR, Keating RO, Lee WD, Paradis GA, Begum S, Hynes RO, Wittrup KD. Determination of 35 cell surface antigen levels in malignant pleural effusions identifies CD24 as a marker of disseminated tumor cells. International Journal of Cancer. Journal International Du Cancer. 133: 2925-33. PMID 23775727 DOI: 10.1002/Ijc.28312 |
0.322 |
|
| 2013 |
Miller PG, Al-Shahrour F, Hartwell KA, Chu LP, Järås M, Puram RV, Puissant A, Callahan KP, Ashton J, McConkey ME, Poveromo LP, Cowley GS, Kharas MG, Labelle M, Shterental S, ... ... Hynes RO, et al. In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling. Cancer Cell. 24: 45-58. PMID 23770013 DOI: 10.1016/J.Ccr.2013.05.004 |
0.339 |
|
| 2013 |
Hynes RO, Begum S, Labelle M. Platelets, Tumor Cell Invasiveness, and Metastasis Blood. 122: SCI-31-SCI-31. DOI: 10.1182/Blood.V122.21.Sci-31.Sci-31 |
0.373 |
|
| 2012 |
Labelle M, Hynes RO. The initial hours of metastasis: the importance of cooperative host-tumor cell interactions during hematogenous dissemination. Cancer Discovery. 2: 1091-9. PMID 23166151 DOI: 10.1158/2159-8290.Cd-12-0329 |
0.358 |
|
| 2012 |
Reticker-Flynn NE, Malta DF, Winslow MM, Lamar JM, Xu MJ, Underhill GH, Hynes RO, Jacks TE, Bhatia SN. A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis. Nature Communications. 3: 1122. PMID 23047680 DOI: 10.1038/Ncomms2128 |
0.343 |
|
| 2012 |
Gupton SL, Riquelme D, Hughes-Alford SK, Tadros J, Rudina SS, Hynes RO, Lauffenburger D, Gertler FB. Mena binds α5 integrin directly and modulates α5β1 function. The Journal of Cell Biology. 198: 657-76. PMID 22908313 DOI: 10.1083/Jcb.201202079 |
0.407 |
|
| 2012 |
Lamar JM, Stern P, Liu H, Schindler JW, Jiang ZG, Hynes RO. The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain. Proceedings of the National Academy of Sciences of the United States of America. 109: E2441-50. PMID 22891335 DOI: 10.1073/Pnas.1212021109 |
0.318 |
|
| 2012 |
Li L, Welser-Alves J, van der Flier A, Boroujerdi A, Hynes RO, Milner R. An angiogenic role for the α5β1 integrin in promoting endothelial cell proliferation during cerebral hypoxia. Experimental Neurology. 237: 46-54. PMID 22721769 DOI: 10.1016/J.Expneurol.2012.06.005 |
0.354 |
|
| 2012 |
Naba A, Clauser KR, Hoersch S, Liu H, Carr SA, Hynes RO. The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices. Molecular & Cellular Proteomics : McP. 11: M111.014647. PMID 22159717 DOI: 10.1074/Mcp.M111.014647 |
0.35 |
|
| 2012 |
Bergmeier W, Hynes RO. Extracellular matrix proteins in hemostasis and thrombosis. Cold Spring Harbor Perspectives in Biology. 4. PMID 21937733 DOI: 10.1101/Cshperspect.A005132 |
0.347 |
|
| 2012 |
Hynes RO, Naba A. Overview of the matrisome--an inventory of extracellular matrix constituents and functions. Cold Spring Harbor Perspectives in Biology. 4: a004903. PMID 21937732 DOI: 10.1101/Cshperspect.A004903 |
0.357 |
|
| 2012 |
Hynes RO, Naba A, Hoersch S, Clauser K, Carr SA. Abstract SY28-01: Multiple changes in tumor extracellular matrices Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Sy28-01 |
0.371 |
|
| 2012 |
Reticker-Flynn NE, Malta DFB, Winslow MM, Xu MJ, Lamar JM, Hynes RO, Jacks TE, Bhatia SN. Abstract 2973: Adhesion of tumor cells to ECM microarrays identifies novel ECM interactions in metastasis Cancer Research. 72: 2973-2973. DOI: 10.1158/1538-7445.Am2012-2973 |
0.371 |
|
| 2012 |
Schnaar R, Paulson JC, Macauley MS, Nycholat C, Pfrengle F, Rademacher C, Mahan A, Dionne K, Suscovich T, Alter G, Katoh T, Kiwamoto T, Brummet M, Bochner B, Tiemeyer M, ... ... Hynes R, et al. Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology Glycobiology. 22: 1518-1650. DOI: 10.1093/Glycob/Cws127 |
0.766 |
|
| 2011 |
Hynes RO. Metastatic cells will take any help they can get. Cancer Cell. 20: 689-90. PMID 22172715 DOI: 10.1016/J.Ccr.2011.11.022 |
0.323 |
|
| 2011 |
Labelle M, Begum S, Hynes RO. Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis. Cancer Cell. 20: 576-90. PMID 22094253 DOI: 10.1016/J.Ccr.2011.09.009 |
0.35 |
|
| 2011 |
Stenzel D, Lundkvist A, Sauvaget D, Busse M, Graupera M, van der Flier A, Wijelath ES, Murray J, Sobel M, Costell M, Takahashi S, Fässler R, Yamaguchi Y, Gutmann DH, Hynes RO, et al. Integrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis. Development (Cambridge, England). 138: 4451-63. PMID 21880786 DOI: 10.1242/Dev.071381 |
0.368 |
|
| 2011 |
Yang L, Chen G, Mohanty S, Scott G, Fazal F, Rahman A, Begum S, Hynes RO, Xu L. GPR56 Regulates VEGF production and angiogenesis during melanoma progression. Cancer Research. 71: 5558-68. PMID 21724588 DOI: 10.1158/0008-5472.Can-10-4543 |
0.396 |
|
| 2011 |
Xie L, Duncan MB, Pahler J, Sugimoto H, Martino M, Lively J, Mundel T, Soubasakos M, Rubin K, Takeda T, Inoue M, Lawler J, Hynes RO, Hanahan D, Kalluri R. Counterbalancing angiogenic regulatory factors control the rate of cancer progression and survival in a stage-specific manner. Proceedings of the National Academy of Sciences of the United States of America. 108: 9939-44. PMID 21622854 DOI: 10.1073/Pnas.1105041108 |
0.327 |
|
| 2011 |
Pulina MV, Hou SY, Mittal A, Julich D, Whittaker CA, Holley SA, Hynes RO, Astrof S. Essential roles of fibronectin in the development of the left-right embryonic body plan. Developmental Biology. 354: 208-20. PMID 21466802 DOI: 10.1016/J.Ydbio.2011.03.026 |
0.346 |
|
| 2011 |
Schachner M, Schoonmaker G, Hynes RO. Cellular and subcellular localization of LETS protein in the nervous system. Brain Research. 158: 149-58. PMID 21348357 DOI: 10.1016/0006-8993(78)90011-2 |
0.381 |
|
| 2011 |
Liu H, Ong SE, Badu-Nkansah K, Schindler J, White FM, Hynes RO. CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis. Proceedings of the National Academy of Sciences of the United States of America. 108: 1379-84. PMID 21220330 DOI: 10.1073/Pnas.1017228108 |
0.332 |
|
| 2011 |
Labelle M, Begum S, Hynes RO. Abstract PR1: Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-Pr1 |
0.345 |
|
| 2010 |
Acharya M, Mukhopadhyay S, Païdassi H, Jamil T, Chow C, Kissler S, Stuart LM, Hynes RO, Lacy-Hulbert A. αv Integrin expression by DCs is required for Th17 cell differentiation and development of experimental autoimmune encephalomyelitis in mice. The Journal of Clinical Investigation. 120: 4445-52. PMID 21099114 DOI: 10.1172/Jci43796 |
0.34 |
|
| 2010 |
Canault M, Certel K, Schatzberg D, Wagner DD, Hynes RO. The lack of ADAM17 activity during embryonic development causes hemorrhage and impairs vessel formation. Plos One. 5: e13433. PMID 20976179 DOI: 10.1371/Journal.Pone.0013433 |
0.54 |
|
| 2010 |
van der Flier A, Badu-Nkansah K, Whittaker CA, Crowley D, Bronson RT, Lacy-Hulbert A, Hynes RO. Endothelial alpha5 and alphav integrins cooperate in remodeling of the vasculature during development. Development (Cambridge, England). 137: 2439-49. PMID 20570943 DOI: 10.1242/Dev.049551 |
0.612 |
|
| 2010 |
Xu L, Begum S, Barry M, Crowley D, Yang L, Bronson RT, Hynes RO. GPR56 plays varying roles in endogenous cancer progression. Clinical & Experimental Metastasis. 27: 241-9. PMID 20333450 DOI: 10.1007/S10585-010-9322-3 |
0.389 |
|
| 2010 |
Marchetti G, Escuin S, van der Flier A, De Arcangelis A, Hynes RO, Georges-Labouesse E. Integrin alpha5beta1 is necessary for regulation of radial migration of cortical neurons during mouse brain development. The European Journal of Neuroscience. 31: 399-409. PMID 20105241 DOI: 10.1111/J.1460-9568.2009.07072.X |
0.309 |
|
| 2009 |
Hynes RO. The extracellular matrix: not just pretty fibrils. Science (New York, N.Y.). 326: 1216-9. PMID 19965464 DOI: 10.1126/Science.1176009 |
0.38 |
|
| 2009 |
Sobolev O, Stern P, Lacy-Hulbert A, Hynes RO. Natural killer cells require selectins for suppression of subcutaneous tumors. Cancer Research. 69: 2531-9. PMID 19258505 DOI: 10.1158/0008-5472.Can-08-3126 |
0.368 |
|
| 2009 |
Astrof S, Hynes RO. Fibronectins in vascular morphogenesis. Angiogenesis. 12: 165-75. PMID 19219555 DOI: 10.1007/S10456-009-9136-6 |
0.346 |
|
| 2008 |
Stern P, Astrof S, Erkeland SJ, Schustak J, Sharp PA, Hynes RO. A system for Cre-regulated RNA interference in vivo. Proceedings of the National Academy of Sciences of the United States of America. 105: 13895-900. PMID 18779577 DOI: 10.1073/Pnas.0806907105 |
0.329 |
|
| 2008 |
Li S, Jin Z, Koirala S, Bu L, Xu L, Hynes RO, Walsh CA, Corfas G, Piao X. GPR56 regulates pial basement membrane integrity and cortical lamination. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 5817-26. PMID 18509043 DOI: 10.1523/Jneurosci.0853-08.2008 |
0.386 |
|
| 2008 |
Xu L, Shen SS, Hoshida Y, Subramanian A, Ross K, Brunet JP, Wagner SN, Ramaswamy S, Mesirov JP, Hynes RO. Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastases. Molecular Cancer Research : McR. 6: 760-9. PMID 18505921 DOI: 10.1158/1541-7786.Mcr-07-0344 |
0.386 |
|
| 2008 |
McCarty JH, Barry M, Crowley D, Bronson RT, Lacy-Hulbert A, Hynes RO. Genetic ablation of alphav integrins in epithelial cells of the eyelid skin and conjunctiva leads to squamous cell carcinoma. The American Journal of Pathology. 172: 1740-7. PMID 18467691 DOI: 10.2353/Ajpath.2008.070700 |
0.375 |
|
| 2008 |
Wong SY, Crowley D, Bronson RT, Hynes RO. Analyses of the role of endogenous SPARC in mouse models of prostate and breast cancer. Clinical & Experimental Metastasis. 25: 109-18. PMID 18058030 DOI: 10.1007/S10585-007-9126-2 |
0.316 |
|
| 2008 |
Shinde AV, Bystroff C, Wang C, Vogelezang MG, Vincent PA, Hynes RO, Van De Water L. Identification of the peptide sequences within the EIIIA (EDA) segment of fibronectin that mediate integrin alpha9beta1-dependent cellular activities. The Journal of Biological Chemistry. 283: 2858-70. PMID 17967897 DOI: 10.1074/Jbc.M708306200 |
0.341 |
|
| 2008 |
Eshghi S, Vogelezang MG, Hynes RO, Griffith LG, Lodish HF. α4β1 integrin and erythropoietin mediate temporally distinct steps in erythropoiesis: Integrins in red cell development (Journal of Cell Biology (2007) 177, 5, (871-880)) Journal of Cell Biology. 181: 395. DOI: 10.1083/Jcb.20070208020080326A |
0.322 |
|
| 2007 |
Lacy-Hulbert A, Smith AM, Tissire H, Barry M, Crowley D, Bronson RT, Roes JT, Savill JS, Hynes RO. Ulcerative colitis and autoimmunity induced by loss of myeloid alphav integrins. Proceedings of the National Academy of Sciences of the United States of America. 104: 15823-8. PMID 17895374 DOI: 10.1073/Pnas.0707421104 |
0.327 |
|
| 2007 |
Astrof S, Crowley D, Hynes RO. Multiple cardiovascular defects caused by the absence of alternatively spliced segments of fibronectin. Developmental Biology. 311: 11-24. PMID 17706958 DOI: 10.1016/J.Ydbio.2007.07.005 |
0.34 |
|
| 2007 |
Wong SY, Haack H, Kissil JL, Barry M, Bronson RT, Shen SS, Whittaker CA, Crowley D, Hynes RO. Protein 4.1B suppresses prostate cancer progression and metastasis. Proceedings of the National Academy of Sciences of the United States of America. 104: 12784-9. PMID 17640904 DOI: 10.1073/Pnas.0705499104 |
0.575 |
|
| 2007 |
Hynes RO. Cell-matrix adhesion in vascular development. Journal of Thrombosis and Haemostasis : Jth. 5: 32-40. PMID 17635706 DOI: 10.1111/J.1538-7836.2007.02569.X |
0.369 |
|
| 2007 |
Xu L, Hynes RO. GPR56 and TG2: possible roles in suppression of tumor growth by the microenvironment. Cell Cycle (Georgetown, Tex.). 6: 160-5. PMID 17314516 DOI: 10.4161/Cc.6.2.3760 |
0.439 |
|
| 2007 |
Zou Z, Chen H, Schmaier AA, Hynes RO, Kahn ML. Structure-function analysis reveals discrete beta3 integrin inside-out and outside-in signaling pathways in platelets. Blood. 109: 3284-90. PMID 17170121 DOI: 10.1182/Blood-2006-10-051664 |
0.304 |
|
| 2007 |
Xu L, Begum S, Hearn JD, Hynes RO. GPR56 binds tissue transglutaminase and inhibits melanoma tumor growth and metastasis The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A267-D |
0.349 |
|
| 2006 |
Sodergren E, Weinstock GM, Davidson EH, Cameron RA, Gibbs RA, Angerer RC, Angerer LM, Arnone MI, Burgess DR, Burke RD, Coffman JA, Dean M, Elphick MR, Ettensohn CA, ... ... Hynes RO, et al. The genome of the sea urchin Strongylocentrotus purpuratus. Science (New York, N.Y.). 314: 941-52. PMID 17095691 DOI: 10.1126/Science.1133609 |
0.528 |
|
| 2006 |
Whittaker CA, Bergeron KF, Whittle J, Brandhorst BP, Burke RD, Hynes RO. The echinoderm adhesome. Developmental Biology. 300: 252-66. PMID 16950242 DOI: 10.1016/J.Ydbio.2006.07.044 |
0.637 |
|
| 2006 |
Yang H, Reheman A, Chen P, Zhu G, Hynes RO, Freedman J, Wagner DD, Ni H. Fibrinogen and von Willebrand factor-independent platelet aggregation in vitro and in vivo. Journal of Thrombosis and Haemostasis : Jth. 4: 2230-7. PMID 16824188 DOI: 10.1111/J.1538-7836.2006.02116.X |
0.53 |
|
| 2006 |
Xu L, Begum S, Hearn JD, Hynes RO. GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis. Proceedings of the National Academy of Sciences of the United States of America. 103: 9023-8. PMID 16757564 DOI: 10.1073/Pnas.0602681103 |
0.391 |
|
| 2006 |
Matuskova J, Chauhan AK, Cambien B, Astrof S, Dole VS, Piffath CL, Hynes RO, Wagner DD. Decreased plasma fibronectin leads to delayed thrombus growth in injured arterioles. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 1391-6. PMID 16528004 DOI: 10.1161/01.Atv.0000216282.58291.C6 |
0.542 |
|
| 2006 |
Staquet MJ, Couble ML, Roméas A, Connolly M, Magloire H, Hynes RO, Clezardin P, Bleicher F, Farges JC. Expression and localisation of alphav integrins in human odontoblasts. Cell and Tissue Research. 323: 457-63. PMID 16341551 DOI: 10.1007/S00441-005-0104-1 |
0.313 |
|
| 2006 |
Ni H, Chen P, Spring CM, Sayeh E, Semple JW, Lazarus AH, Hynes RO, Freedman J. A novel murine model of fetal and neonatal alloimmune thrombocytopenia: response to intravenous IgG therapy. Blood. 107: 2976-83. PMID 16317099 DOI: 10.1182/Blood-2005-06-2562 |
0.308 |
|
| 2005 |
Taverna D, Crowley D, Connolly M, Bronson RT, Hynes RO. A direct test of potential roles for beta3 and beta5 integrins in growth and metastasis of murine mammary carcinomas. Cancer Research. 65: 10324-9. PMID 16288021 DOI: 10.1158/0008-5472.Can-04-4098 |
0.348 |
|
| 2005 |
McCarty JH, Cook AA, Hynes RO. An interaction between {alpha}v{beta}8 integrin and Band 4.1B via a highly conserved region of the Band 4.1 C-terminal domain. Proceedings of the National Academy of Sciences of the United States of America. 102: 13479-83. PMID 16157875 DOI: 10.1073/Pnas.0506068102 |
0.309 |
|
| 2005 |
Fang J, Hodivala-Dilke K, Johnson BD, Du LM, Hynes RO, White GC, Wilcox DA. Therapeutic expression of the platelet-specific integrin, alphaIIbbeta3, in a murine model for Glanzmann thrombasthenia. Blood. 106: 2671-9. PMID 15972454 DOI: 10.1182/Blood-2004-12-4619 |
0.376 |
|
| 2005 |
Bono P, Cordero E, Johnson K, Borowsky M, Ramesh V, Jacks T, Hynes RO. Layilin, a cell surface hyaluronan receptor, interacts with merlin and radixin. Experimental Cell Research. 308: 177-87. PMID 15913605 DOI: 10.1016/J.Yexcr.2005.04.017 |
0.317 |
|
| 2005 |
Yang H, Reheman A, Chen P, Hynes RO, Freedman J, Wagner DD, Ni H. Fibrinogen and von Willebrand Factor-Independent Platelet Aggregation: The Essential Roles of β3 Integrin, Thrombin, and Divalent Ca2+ Cations. Blood. 106: 2651-2651. DOI: 10.1182/Blood.V106.11.2651.2651 |
0.508 |
|
| 2004 |
Singh P, Reimer CL, Peters JH, Stepp MA, Hynes RO, Van De Water L. The spatial and temporal expression patterns of integrin alpha9beta1 and one of its ligands, the EIIIA segment of fibronectin, in cutaneous wound healing. The Journal of Investigative Dermatology. 123: 1176-81. PMID 15610531 DOI: 10.1111/J.0022-202X.2004.23485.X |
0.332 |
|
| 2004 |
Hynes RO. The emergence of integrins: a personal and historical perspective. Matrix Biology : Journal of the International Society For Matrix Biology. 23: 333-40. PMID 15533754 DOI: 10.1016/J.Matbio.2004.08.001 |
0.378 |
|
| 2004 |
Astrof S, Crowley D, George EL, Fukuda T, Sekiguchi K, Hanahan D, Hynes RO. Direct test of potential roles of EIIIA and EIIIB alternatively spliced segments of fibronectin in physiological and tumor angiogenesis. Molecular and Cellular Biology. 24: 8662-70. PMID 15367684 DOI: 10.1128/Mcb.24.19.8662-8670.2004 |
0.321 |
|
| 2004 |
Taverna D, Moher H, Crowley D, Borsig L, Varki A, Hynes RO. Increased primary tumor growth in mice null for beta3- or beta3/beta5-integrins or selectins. Proceedings of the National Academy of Sciences of the United States of America. 101: 763-8. PMID 14718670 DOI: 10.1073/Pnas.0307289101 |
0.355 |
|
| 2003 |
Alugupalli KR, Michelson AD, Joris I, Schwan TG, Hodivala-Dilke K, Hynes RO, Leong JM. Spirochete-platelet attachment and thrombocytopenia in murine relapsing fever borreliosis. Blood. 102: 2843-50. PMID 12855586 DOI: 10.1182/Blood-2003-02-0426 |
0.319 |
|
| 2003 |
Hamano Y, Zeisberg M, Sugimoto H, Lively JC, Maeshima Y, Yang C, Hynes RO, Werb Z, Sudhakar A, Kalluri R. Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin. Cancer Cell. 3: 589-601. PMID 12842087 DOI: 10.1016/S1535-6108(03)00133-8 |
0.358 |
|
| 2003 |
Hynes RO. Metastatic potential: generic predisposition of the primary tumor or rare, metastatic variants-or both? Cell. 113: 821-3. PMID 12837240 DOI: 10.1016/S0092-8674(03)00468-9 |
0.301 |
|
| 2003 |
Ni H, Yuen PS, Papalia JM, Trevithick JE, Sakai T, Fässler R, Hynes RO, Wagner DD. Plasma fibronectin promotes thrombus growth and stability in injured arterioles. Proceedings of the National Academy of Sciences of the United States of America. 100: 2415-9. PMID 12606706 DOI: 10.1073/Pnas.2628067100 |
0.737 |
|
| 2002 |
Whittaker CA, Hynes RO. Distribution and evolution of von Willebrand/integrin A domains: widely dispersed domains with roles in cell adhesion and elsewhere. Molecular Biology of the Cell. 13: 3369-87. PMID 12388743 DOI: 10.1091/Mbc.E02-05-0259 |
0.607 |
|
| 2002 |
McCarty JH, Monahan-Earley RA, Brown LF, Keller M, Gerhardt H, Rubin K, Shani M, Dvorak HF, Wolburg H, Bader BL, Dvorak AM, Hynes RO. Defective associations between blood vessels and brain parenchyma lead to cerebral hemorrhage in mice lacking alphav integrins. Molecular and Cellular Biology. 22: 7667-77. PMID 12370313 DOI: 10.1128/Mcb.22.21.7667-7677.2002 |
0.339 |
|
| 2002 |
Francis SE, Goh KL, Hodivala-Dilke K, Bader BL, Stark M, Davidson D, Hynes RO. Central roles of alpha5beta1 integrin and fibronectin in vascular development in mouse embryos and embryoid bodies. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 927-33. PMID 12067900 DOI: 10.1161/01.Atv.0000016045.93313.F2 |
0.608 |
|
| 2002 |
André P, Prasad KS, Denis CV, He M, Papalia JM, Hynes RO, Phillips DR, Wagner DD. CD40L stabilizes arterial thrombi by a beta3 integrin--dependent mechanism. Nature Medicine. 8: 247-52. PMID 11875495 DOI: 10.1038/Nm0302-247 |
0.534 |
|
| 2002 |
Borsig L, Wong R, Hynes RO, Varki NM, Varki A. Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis. Proceedings of the National Academy of Sciences of the United States of America. 99: 2193-8. PMID 11854515 DOI: 10.1073/Pnas.261704098 |
0.378 |
|
| 2002 |
Alcamo E, Hacohen N, Schulte LC, Rennert PD, Hynes RO, Baltimore D. Requirement for the NF-kappaB family member RelA in the development of secondary lymphoid organs. The Journal of Experimental Medicine. 195: 233-44. PMID 11805150 DOI: 10.1084/Jem.20011885 |
0.304 |
|
| 2002 |
Reynolds LE, Wyder L, Lively JC, Taverna D, Robinson SD, Huang X, Sheppard D, Hynes RO, Hodivala-Dilke KM. Enhanced pathological angiogenesis in mice lacking beta3 integrin or beta3 and beta5 integrins. Nature Medicine. 8: 27-34. PMID 11786903 DOI: 10.1038/Nm0102-27 |
0.316 |
|
| 2002 |
Maeshima Y, Sudhakar A, Lively JC, Ueki K, Kharbanda S, Kahn CR, Sonenberg N, Hynes RO, Kalluri R. Tumstatin, an endothelial cell-specific inhibitor of protein synthesis. Science (New York, N.Y.). 295: 140-3. PMID 11778052 DOI: 10.1126/Science.1065298 |
0.341 |
|
| 2001 |
Lawler J, Miao WM, Duquette M, Bouck N, Bronson RT, Hynes RO. Thrombospondin-1 gene expression affects survival and tumor spectrum of p53-deficient mice. The American Journal of Pathology. 159: 1949-56. PMID 11696456 DOI: 10.1016/S0002-9440(10)63042-8 |
0.336 |
|
| 2001 |
Alcamo E, Mizgerd JP, Horwitz BH, Bronson R, Beg AA, Scott M, Doerschuk CM, Hynes RO, Baltimore D. Targeted mutation of TNF receptor I rescues the RelA-deficient mouse and reveals a critical role for NF-kappa B in leukocyte recruitment. Journal of Immunology (Baltimore, Md. : 1950). 167: 1592-600. PMID 11466381 DOI: 10.4049/Jimmunol.167.3.1592 |
0.316 |
|
| 2001 |
DiPersio CM, Trevithick JE, Hynes RO. Functional comparison of the alpha3A and alpha3B cytoplasmic domain variants of the chicken alpha3 integrin subunit. Experimental Cell Research. 268: 45-60. PMID 11461117 DOI: 10.1006/Excr.2001.5273 |
0.333 |
|
| 2001 |
Niederman R, Westernoff T, Lee C, Mark LL, Kawashima N, Ullman-Culler M, Dewhirst FE, Paster BJ, Wagner DD, Mayadas T, Hynes RO, Stashenko P. Infection-mediated early-onset periodontal disease in P/E-selectin-deficient mice. Journal of Clinical Periodontology. 28: 569-75. PMID 11350525 DOI: 10.1034/J.1600-051X.2001.028006569.X |
0.522 |
|
| 2001 |
Haack H, Hynes RO. Integrin receptors are required for cell survival and proliferation during development of the peripheral glial lineage. Developmental Biology. 233: 38-55. PMID 11319856 DOI: 10.1006/Dbio.2001.0213 |
0.346 |
|
| 2001 |
Bono P, Rubin K, Higgins JM, Hynes RO. Layilin, a novel integral membrane protein, is a hyaluronan receptor. Molecular Biology of the Cell. 12: 891-900. PMID 11294894 DOI: 10.1091/Mbc.12.4.891 |
0.335 |
|
| 2001 |
Wheeler GN, Hynes RO. The cloning, genomic organization and expression of the focal contact protein paxillin in Drosophila. Gene. 262: 291-9. PMID 11179695 DOI: 10.1016/S0378-1119(00)00512-6 |
0.35 |
|
| 2000 |
André P, Denis CV, Ware J, Saffaripour S, Hynes RO, Ruggeri ZM, Wagner DD. Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins. Blood. 96: 3322-8. PMID 11071623 DOI: 10.1182/Blood.V96.10.3322.H8003322_3322_3328 |
0.546 |
|
| 2000 |
Arroyo AG, Taverna D, Whittaker CA, Strauch UG, Bader BL, Rayburn H, Crowley D, Parker CM, Hynes RO. In vivo roles of integrins during leukocyte development and traffic: insights from the analysis of mice chimeric for alpha 5, alpha v, and alpha 4 integrins. Journal of Immunology (Baltimore, Md. : 1950). 165: 4667-75. PMID 11035110 DOI: 10.4049/Jimmunol.165.8.4667 |
0.573 |
|
| 2000 |
Clark EA, Golub TR, Lander ES, Hynes RO. Genomic analysis of metastasis reveals an essential role for RhoC. Nature. 406: 532-5. PMID 10952316 DOI: 10.1038/35020106 |
0.338 |
|
| 2000 |
Ni H, Denis CV, Subbarao S, Degen JL, Sato TN, Hynes RO, Wagner DD. Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen. The Journal of Clinical Investigation. 106: 385-92. PMID 10930441 DOI: 10.1172/Jci9896 |
0.549 |
|
| 2000 |
Hynes RO, Zhao Q. The evolution of cell adhesion Journal of Cell Biology. 150: F89-F95. PMID 10908592 DOI: 10.1083/Jcb.150.2.F89 |
0.317 |
|
| 2000 |
McHugh KP, Hodivala-Dilke K, Zheng MH, Namba N, Jonathan L, Novack D, Feng X, Ross FP, Hynes RO, Teitelbaum SL. Mice lacking β3 integrins are osteosclerotic because of dysfunctional osteoclasts Journal of Clinical Investigation. 105: 433-440. PMID 10683372 DOI: 10.1172/Jci8905 |
0.347 |
|
| 1999 |
Hynes RO. Cell adhesion: Old and new questions Trends in Cell Biology. 9: M33-M37. PMID 10611678 DOI: 10.1016/S0968-0004(99)01479-6 |
0.37 |
|
| 1999 |
Fox GL, Rebay I, Hynes RO. Expression of DFak56, a Drosophila homolog of vertebrate focal adhesion kinase, supports a role in cell migration in vivo. Proceedings of the National Academy of Sciences of the United States of America. 96: 14978-83. PMID 10611323 DOI: 10.1073/Pnas.96.26.14978 |
0.372 |
|
| 1999 |
Hynes RO, Hodivala-Dilke KM. Insights and questions arising from studies of a mouse model of Glanzmann thrombasthenia Thrombosis and Haemostasis. 82: 481-485. PMID 10605739 DOI: 10.1055/S-0037-1615868 |
0.323 |
|
| 1999 |
Arroyo AG, Yang JT, Rayburn H, Hynes RO. α4 integrins regulate the proliferation/differentiation balance of multilineage hematopoietic progenitors in vivo Immunity. 11: 555-566. PMID 10591181 DOI: 10.1016/S1074-7613(00)80131-4 |
0.311 |
|
| 1999 |
Lyden D, Young AZ, Zagzag D, Yan W, Gerald W, O'Reilly R, Bader BL, Hynes RO, Zhuang Y, Manova K, Benezra R. Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts. Nature. 401: 670-7. PMID 10537105 DOI: 10.1038/44334 |
0.362 |
|
| 1999 |
Robinson SD, Frenette PS, Rayburn H, Cummiskey M, Ullman-Culleré M, Wagner DD, Hynes RO. Multiple, targeted deficiencies in selectins reveal a predominant role for P-selectin in leukocyte recruitment. Proceedings of the National Academy of Sciences of the United States of America. 96: 11452-7. PMID 10500197 DOI: 10.1073/Pnas.96.20.11452 |
0.655 |
|
| 1999 |
Kawashima N, Niederman R, Hynes RO, Ullmann-Cullere M, Stashenko P. Infection-stimulated infraosseus inflammation and bone destruction is increased in P-/E-selectin knockout mice Immunology. 97: 117-123. PMID 10447722 DOI: 10.1046/J.1365-2567.1999.00754.X |
0.302 |
|
| 1999 |
Hynes RO, Bader BL, Hodivala-Dilke K. Integrins in vascular development Brazilian Journal of Medical and Biological Research. 32: 501-510. PMID 10412560 DOI: 10.1590/S0100-879X1999000500002 |
0.38 |
|
| 1999 |
Bloom L, Ingham KC, Hynes RO. Fibronectin regulates assembly of actin filaments and focal contacts in cultured cells via the heparin-binding site in repeat III13. Molecular Biology of the Cell. 10: 1521-36. PMID 10233160 DOI: 10.1091/Mbc.10.5.1521 |
0.312 |
|
| 1999 |
Saoncella S, Echtermeyer F, Denhez F, Nowlen JK, Mosher DF, Robinson SD, Hynes RO, Goetinck PF. Syndecan-4 signals cooperatively with integrins in a Rho-dependent manner in the assembly of focal adhesions and actin stress fibers. Proceedings of the National Academy of Sciences of the United States of America. 96: 2805-10. PMID 10077592 DOI: 10.1073/Pnas.96.6.2805 |
0.344 |
|
| 1999 |
Hynes RO. The dynamic dialogue between cells and matrices: Implications of fibronectin's elasticity Proceedings of the National Academy of Sciences of the United States of America. 96: 2588-2590. PMID 10077553 DOI: 10.1073/Pnas.96.6.2588 |
0.347 |
|
| 1999 |
Robert C, Fuhlbrigge RC, Kieffer JD, Ayehunie S, Hynes RO, Cheng G, Grabbe S, Von Andrian UH, Kupper TS. Interaction of dendritic cells with skin endothelium: A new perspective on immunosurveillance Journal of Experimental Medicine. 189: 627-635. PMID 9989977 DOI: 10.1084/Jem.189.4.627 |
0.317 |
|
| 1999 |
Hodivala-Dilke KM, McHugh KP, Tsakiris DA, Rayburn H, Crowley D, Ullman-Culleré M, Ross FP, Coller BS, Teitelbaum S, Hynes RO. β3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival Journal of Clinical Investigation. 103: 229-238. PMID 9916135 DOI: 10.1172/Jci5487 |
0.337 |
|
| 1998 |
Bader BL, Rayburn H, Crowley D, Hynes RO. Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all αv integrins Cell. 95: 507-519. PMID 9827803 DOI: 10.1016/S0092-8674(00)81618-9 |
0.355 |
|
| 1998 |
Hartwell DW, Mayadas TN, Berger G, Frenette PS, Rayburn H, Hynes RO, Wagner DD. Role of P-selectin cytoplasmic domain in granular targeting in vivo and in early inflammatory responses. The Journal of Cell Biology. 143: 1129-41. PMID 9817767 DOI: 10.1083/Jcb.143.4.1129 |
0.685 |
|
| 1998 |
Hartwell DW, Butterfield CE, Frenette PS, Kenyon BM, Hynes RO, Folkman J, Wagner DD. Angiogenesis in P- and E-selectin-deficient mice. Microcirculation (New York, N.Y. : 1994). 5: 173-8. PMID 9789257 DOI: 10.1111/J.1549-8719.1998.Tb00066.X |
0.667 |
|
| 1998 |
Borowsky ML, Hynes RO. Layilin, a novel talin-binding transmembrane protein homologous with C- type lectins, is localized in membrane ruffles Journal of Cell Biology. 143: 429-442. PMID 9786953 DOI: 10.1083/Jcb.143.2.429 |
0.345 |
|
| 1998 |
Homeister JW, Zhang M, Frenette PS, Hynes RO, Wagner DD, Lowe JB, Marks RM. Overlapping functions of E- and P-selectin in neutrophil recruitment during acute inflammation. Blood. 92: 2345-52. PMID 9746773 DOI: 10.1182/Blood.V92.7.2345.2345_2345_2352 |
0.657 |
|
| 1998 |
Hodivala-Dilke KM, DiPersio CM, Kreidberg JA, Hynes RO. Novel roles for α3β1 integrin as a regulator of cytoskeletal assembly and as a trans-dominant inhibitor of integrin receptor function in mouse keratinocytes Journal of Cell Biology. 142: 1357-1369. PMID 9732295 DOI: 10.1083/Jcb.142.5.1357 |
0.348 |
|
| 1998 |
Seiler KP, Ma Y, Weis JH, Frenette PS, Hynes RO, Wagner DD, Weis JJ. E and P selectins are not required for resistance to severe murine lyme arthritis. Infection and Immunity. 66: 4557-9. PMID 9712820 DOI: 10.1128/Iai.66.9.4557-4559.1998 |
0.647 |
|
| 1998 |
Denis C, Methia N, Frenette PS, Rayburn H, Ullman-Culleré M, Hynes RO, Wagner DD. A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis. Proceedings of the National Academy of Sciences of the United States of America. 95: 9524-9. PMID 9689113 DOI: 10.1073/Pnas.95.16.9524 |
0.657 |
|
| 1998 |
Mazo IB, Gutierrez-Ramos JC, Frenette PS, Hynes RO, Wagner DD, von Andrian UH. Hematopoietic progenitor cell rolling in bone marrow microvessels: parallel contributions by endothelial selectins and vascular cell adhesion molecule 1. The Journal of Experimental Medicine. 188: 465-74. PMID 9687524 DOI: 10.1084/Jem.188.3.465 |
0.682 |
|
| 1998 |
Clark EA, King WG, Brugge JS, Symons M, Hynes RO. Integrin-mediated signals regulated by members of the rho family of gtpases Journal of Cell Biology. 142: 573-586. PMID 9679153 DOI: 10.1083/Jcb.142.2.573 |
0.307 |
|
| 1998 |
Dong ZM, Chapman SM, Brown AA, Frenette PS, Hynes RO, Wagner DD. The combined role of P- and E-selectins in atherosclerosis. The Journal of Clinical Investigation. 102: 145-52. PMID 9649568 DOI: 10.1172/Jci3001 |
0.642 |
|
| 1998 |
Lawler J, Sunday M, Thibert V, Duquette M, George EL, Rayburn H, Hynes RO. Thrombospondin-1 is required for normal murine pulmonary homeostasis and its absence causes pneumonia Journal of Clinical Investigation. 101: 982-992. PMID 9486968 DOI: 10.1172/Jci1684 |
0.363 |
|
| 1998 |
Frenette PS, Moyna C, Hartwell DW, Lowe JB, Hynes RO, Wagner DD. Platelet-endothelial interactions in inflamed mesenteric venules. Blood. 91: 1318-24. PMID 9454762 DOI: 10.1182/Blood.V91.4.1318 |
0.669 |
|
| 1997 |
George EL, Baldwin HS, Hynes RO. Fibronectins are essential for heart and blood vessel morphogenesis but are dispensable for initial specification of precursor cells Blood. 90: 3073-3081. PMID 9376588 DOI: 10.1182/Blood.V90.8.3073 |
0.365 |
|
| 1997 |
Radice GL, Ferreira-Cornwell MC, Robinson SD, Rayburn H, Chodosh LA, Takeichi M, Hynes RO. Precocious mammary gland development in P-cadherin-deficient mice. The Journal of Cell Biology. 139: 1025-32. PMID 9362520 DOI: 10.1083/Jcb.139.4.1025 |
0.384 |
|
| 1997 |
Hedjran F, Yeakley JM, Huh GS, Hynes RO, Rosenfeld MG. Control of alternative pre-mRNA splicing by distributed pentameric repeats. Proceedings of the National Academy of Sciences of the United States of America. 94: 12343-7. PMID 9356451 DOI: 10.1073/Pnas.94.23.12343 |
0.307 |
|
| 1997 |
Walter UM, Ayer LM, Manning AM, Frenette PS, Wagner DD, Hynes RO, Wolitzky BA, Issekutz AC. Generation and characterization of a novel adhesion function blocking monoclonal antibody recognizing both rat and mouse E-selectin. Hybridoma. 16: 355-61. PMID 9309426 DOI: 10.1089/Hyb.1997.16.355 |
0.655 |
|
| 1997 |
Charlton CA, Mohler WA, Radice GL, Hynes RO, Blau HM. Fusion competence of myoblasts rendered genetically null for N-cadherin in culture Journal of Cell Biology. 138: 331-336. PMID 9230075 DOI: 10.1083/Jcb.138.2.331 |
0.302 |
|
| 1997 |
Walter UM, Ayer LM, Wolitzky BA, Wagner DD, Hynes RO, Manning AM, Issekutz AC. Characterization of a novel adhesion function blocking monoclonal antibody to rat/mouse P-selectin generated in the P-selectin-deficient mouse. Hybridoma. 16: 249-57. PMID 9219035 DOI: 10.1089/Hyb.1997.16.249 |
0.533 |
|
| 1997 |
DiPersio CM, Hodivala-Dilke KM, Jaenisch R, Kreidberg JA, Hynes RO. alpha3beta1 Integrin is required for normal development of the epidermal basement membrane. The Journal of Cell Biology. 137: 729-42. PMID 9151677 DOI: 10.1083/Jcb.137.3.729 |
0.319 |
|
| 1997 |
Johnson RC, Chapman SM, Dong ZM, Ordovas JM, Mayadas TN, Herz J, Hynes RO, Schaefer EJ, Wagner DD. Absence of P-selectin delays fatty streak formation in mice. The Journal of Clinical Investigation. 99: 1037-43. PMID 9062362 DOI: 10.1172/Jci119231 |
0.552 |
|
| 1997 |
Radice GL, Rayburn H, Matsunami H, Knudsen KA, Takeichi M, Hynes RO. Developmental defects in mouse embryos lacking N-cadherin. Developmental Biology. 181: 64-78. PMID 9015265 DOI: 10.1006/Dbio.1996.8443 |
0.311 |
|
| 1996 |
Frenette PS, Mayadas TN, Rayburn H, Hynes RO, Wagner DD. Double knockout highlights value of endothelial selectins. Immunology Today. 17: 205. PMID 8991376 DOI: 10.1016/0167-5699(96)80555-X |
0.62 |
|
| 1996 |
Hynes RO, Wagner DD. Genetic manipulation of vascular adhesion molecules in mice. The Journal of Clinical Investigation. 98: 2193-5. PMID 8941633 DOI: 10.1172/Jci119027 |
0.519 |
|
| 1996 |
Yang JT, Hynes RO. Fibronectin receptor functions in embryonic cells deficient in α5β1 integrin can be replaced by α(v) integrins Molecular Biology of the Cell. 7: 1737-1748. PMID 8930896 DOI: 10.1091/Mbc.7.11.1737 |
0.314 |
|
| 1996 |
Yang JT, Rando TA, Mohler WA, Rayburn H, Blau HM, Hynes RO. Genetic analysis of α4 integrin functions in the development of mouse skeletal muscle Journal of Cell Biology. 135: 829-835. PMID 8909554 DOI: 10.1083/Jcb.135.3.829 |
0.319 |
|
| 1996 |
Georges-Labouesse EN, George EL, Rayburn H, Hynes RO. Mesodermal development in mouse embryos mutant for fibronectin Developmental Dynamics. 207: 145-156. PMID 8906418 DOI: 10.1002/(Sici)1097-0177(199610)207:2<145::Aid-Aja3>3.0.Co;2-H |
0.323 |
|
| 1996 |
Mayadas TN, Mendrick DL, Brady HR, Tang T, Papayianni A, Assmann KJ, Wagner DD, Hynes RO, Cotran RS. Acute passive anti-glomerular basement membrane nephritis in P-selectin-deficient mice. Kidney International. 49: 1342-9. PMID 8731099 DOI: 10.1038/Ki.1996.190 |
0.557 |
|
| 1996 |
Arroyo AG, Yang JT, Rayburn H, Hynes RO. Differential requirements for α4 integrins during fetal and adult hematopoiesis Cell. 85: 997-1008. PMID 8674127 DOI: 10.1016/S0092-8674(00)81301-X |
0.321 |
|
| 1996 |
Tang T, Frenette PS, Hynes RO, Wagner DD, Mayadas TN. Cytokine-induced meningitis is dramatically attenuated in mice deficient in endothelial selectins. The Journal of Clinical Investigation. 97: 2485-90. PMID 8647940 DOI: 10.1172/Jci118695 |
0.661 |
|
| 1996 |
Subramaniam M, Frenette PS, Saffaripour S, Johnson RC, Hynes RO, Wagner DD. Defects in hemostasis in P-selectin-deficient mice. Blood. 87: 1238-42. PMID 8608210 DOI: 10.1182/Blood.V87.4.1238.Bloodjournal8741238 |
0.668 |
|
| 1996 |
Frenette PS, Mayadas TN, Rayburn H, Hynes RO, Wagner DD. Susceptibility to infection and altered hematopoiesis in mice deficient in both P- and E-selectins. Cell. 84: 563-74. PMID 8598043 DOI: 10.1016/S0092-8674(00)81032-6 |
0.667 |
|
| 1996 |
Pinsky DJ, Naka Y, Liao H, Oz MC, Wagner DD, Mayadas TN, Johnson RC, Hynes RO, Heath M, Lawson CA, Stern DM. Hypoxia-induced exocytosis of endothelial cell Weibel-Palade bodies. A mechanism for rapid neutrophil recruitment after cardiac preservation. The Journal of Clinical Investigation. 97: 493-500. PMID 8567972 DOI: 10.1172/Jci118440 |
0.515 |
|
| 1995 |
Zhang S, Holmes TC, DiPersio CM, Hynes RO, Su X, Rich A. Self-complementary oligopeptide matrices support mammalian cell attachment. Biomaterials. 16: 1385-93. PMID 8590765 DOI: 10.1016/0142-9612(95)96874-Y |
0.311 |
|
| 1995 |
George EL, Hynes RO. Gene targeting and generation of mutant mice for studies of cell-extracellular matrix interactions Methods in Enzymology. 245: 386-420. PMID 7760744 DOI: 10.1016/0076-6879(94)45021-8 |
0.345 |
|
| 1995 |
Yamada S, Mayadas TN, Yuan F, Wagner DD, Hynes RO, Melder RJ, Jain RK. Rolling in P-selectin-deficient mice is reduced but not eliminated in the dorsal skin. Blood. 86: 3487-92. PMID 7579454 DOI: 10.1182/Blood.V86.9.3487.Bloodjournal8693487 |
0.539 |
|
| 1995 |
Frenette PS, Johnson RC, Hynes RO, Wagner DD. Platelets roll on stimulated endothelium in vivo: an interaction mediated by endothelial P-selectin. Proceedings of the National Academy of Sciences of the United States of America. 92: 7450-4. PMID 7543682 DOI: 10.1073/Pnas.92.16.7450 |
0.665 |
|
| 1995 |
Subramaniam M, Saffaripour S, Watson SR, Mayadas TN, Hynes RO, Wagner DD. Reduced recruitment of inflammatory cells in a contact hypersensitivity response in P-selectin-deficient mice. The Journal of Experimental Medicine. 181: 2277-82. PMID 7539046 DOI: 10.1084/Jem.181.6.2277 |
0.54 |
|
| 1995 |
Peters JH, Trevithick JE, Johnson P, Hynes RO. Expression of the alternatively spliced EIIIB segment of fibronectin Cell Communication and Adhesion. 3: 67-89. PMID 7538416 DOI: 10.3109/15419069509081278 |
0.315 |
|
| 1995 |
Johnson R, Mayadas T, Frenette P, Mebius R, Subramaniam M, Lacasce A, Hynes R, Wagner D. Blood cell dynamics in P-selectin-deficient mice Blood. 86: 1106-1114. DOI: 10.1182/Blood.V86.3.1106.Bloodjournal8631106 |
0.677 |
|
| 1994 |
Spring J, Paine-Saunders SE, Hynes RO, Bernfield M. Drosophila syndecan: Conservation of a cell-surface heparan sulfate proteoglycan Proceedings of the National Academy of Sciences of the United States of America. 91: 3334-3338. PMID 8159748 DOI: 10.1073/Pnas.91.8.3334 |
0.349 |
|
| 1994 |
Hynes RO. The impact of molecular biology on models for cell adhesion. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 16: 663-9. PMID 7980493 DOI: 10.1002/Bies.950160912 |
0.315 |
|
| 1994 |
Gotwals PJ, Fessler LI, Wehrli M, Hynes RO. Drosophila PS1 integrin is a laminin receptor and differs in ligand specificity from PS2. Proceedings of the National Academy of Sciences of the United States of America. 91: 11447-51. PMID 7972082 DOI: 10.1073/Pnas.91.24.11447 |
0.342 |
|
| 1994 |
Hynes RO. Genetic analyses of cell-matrix interactions in development. Current Opinion in Genetics & Development. 4: 569-74. PMID 7524834 DOI: 10.1016/0959-437X(94)90074-D |
0.351 |
|
| 1994 |
Stepp MA, Urry LA, Hynes RO. Expression of α4 integrin mRNA and protein and fibronectin in the early chicken embryo Cell Communication and Adhesion. 2: 359-375. DOI: 10.3109/15419069409014210 |
0.328 |
|
| 1993 |
Mayadas TN, Johnson RC, Rayburn H, Hynes RO, Wagner DD. Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice. Cell. 74: 541-54. PMID 7688665 DOI: 10.1016/0092-8674(93)80055-J |
0.581 |
|
| 1993 |
Heasman J, Hynes RO, Swan AP, Thomas V, Wylie CC. Primordial germ cells of Xenopus embryos: the role of fibronectin in their adhesion during migration. Cell. 27: 437-47. PMID 6101198 DOI: 10.1016/0092-8674(81)90385-8 |
0.379 |
|
| 1992 |
Hynes RO, Lander AD. Contact and adhesive specificities in the associations, migrations, and targeting of cells and axons. Cell. 68: 303-22. PMID 1733501 DOI: 10.1016/0092-8674(92)90472-O |
0.351 |
|
| 1992 |
DeSimone DW, Norton PA, Hynes RO. Identification and characterization of alternatively spliced fibronectin mRNAs expressed in early Xenopus embryos Developmental Biology. 149: 357-369. PMID 1730390 DOI: 10.1016/0012-1606(92)90291-N |
0.623 |
|
| 1992 |
Hynes RO. Integrins: versatility, modulation, and signaling in cell adhesion. Cell. 69: 11-25. PMID 1555235 DOI: 10.1016/0092-8674(92)90115-S |
0.312 |
|
| 1992 |
Hynes RO. Specificity of cell adhesion in development: the cadherin superfamily. Current Opinion in Genetics & Development. 2: 621-4. PMID 1525517 DOI: 10.1016/S0959-437X(05)80182-0 |
0.378 |
|
| 1992 |
Hynes RO, George EL, Georges EN, Guan JL, Rayburn H, Yang JT. Toward a genetic analysis of cell-matrix adhesion. Cold Spring Harbor Symposia On Quantitative Biology. 57: 249-58. PMID 1339663 DOI: 10.1101/Sqb.1992.057.01.030 |
0.511 |
|
| 1991 |
Guan JL, Trevithick JE, Hynes RO. Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein. Cell Regulation. 2: 951-64. PMID 1725602 DOI: 10.1091/Mbc.2.11.951 |
0.536 |
|
| 1990 |
Guan JL, Trevithick JE, Hynes RO. Retroviral expression of alternatively spliced forms of rat fibronectin. The Journal of Cell Biology. 110: 833-47. PMID 2307710 DOI: 10.1083/Jcb.110.3.833 |
0.546 |
|
| 1990 |
Guan JL, Hynes RO. Lymphoid cells recognize an alternatively spliced segment of fibronectin via the integrin receptor alpha 4 beta 1. Cell. 60: 53-61. PMID 2295088 DOI: 10.1016/0092-8674(90)90715-Q |
0.538 |
|
| 1990 |
Rees DJG, Ades SE, Singer SJ, Hynes RO. Sequence and domain structure of talin Nature. 347: 685-689. PMID 2120593 DOI: 10.1038/347685A0 |
0.368 |
|
| 1990 |
Marcantonio EE, Guan JL, Trevithick JE, Hynes RO. Mapping of the functional determinants of the integrin beta 1 cytoplasmic domain by site-directed mutagenesis. Cell Regulation. 1: 597-604. PMID 2078570 DOI: 10.1091/Mbc.1.8.597 |
0.689 |
|
| 1989 |
Lawler J, Weinstein R, Hynes RO. Cell attachment to thrombospondin: the role of ARG-GLY-ASP, calcium, and integrin receptors. The Journal of Cell Biology. 107: 2351-61. PMID 2848850 DOI: 10.1083/Jcb.107.6.2351 |
0.381 |
|
| 1989 |
Solowska J, Guan JL, Marcantonio EE, Trevithick JE, Buck CA, Hynes RO. Expression of normal and mutant avian integrin subunits in rodent cells. The Journal of Cell Biology. 109: 853-61. PMID 2788168 DOI: 10.1083/Jcb.109.2.853 |
0.708 |
|
| 1989 |
Hynes RO, Marcantonio EE, Stepp MA, Urry LA, Yee GH. Integrin heterodimer and receptor complexity in avian and mammalian cells. The Journal of Cell Biology. 109: 409-20. PMID 2663881 DOI: 10.1083/Jcb.109.1.409 |
0.628 |
|
| 1989 |
Plantefaber LC, Hynes RO. Changes in integrin receptors on oncogenically transformed cells. Cell. 56: 281-90. PMID 2521461 DOI: 10.1016/0092-8674(89)90902-1 |
0.368 |
|
| 1989 |
Lawler J, Hynes R. An integrin receptor on normal and thrombasthenic platelets that binds thrombospondin [see comments] Blood. 74: 2022-2027. DOI: 10.1182/Blood.V74.6.2022.Bloodjournal7462022 |
0.373 |
|
| 1988 |
Marcantonio EE, Hynes RO. Antibodies to the conserved cytoplasmic domain of the integrin beta 1 subunit react with proteins in vertebrates, invertebrates, and fungi. The Journal of Cell Biology. 106: 1765-72. PMID 3131349 DOI: 10.1083/Jcb.106.5.1765 |
0.621 |
|
| 1988 |
Norton PA, Hynes RO. Alternative splicing of chicken fibronectin in embryos and in normal and transformed cells. Molecular and Cellular Biology. 7: 4297-307. PMID 2830487 DOI: 10.1128/mcb.7.12.4297-4307.1987 |
0.315 |
|
| 1987 |
Patel RS, Odermatt E, Schwarzbauer JE, Hynes RO. Organization of the fibronectin gene provides evidence for exon shuffling during evolution. The Embo Journal. 6: 2565-72. PMID 3119323 DOI: 10.1002/J.1460-2075.1987.Tb02545.X |
0.512 |
|
| 1987 |
Hynes RO. Integrins: a family of cell surface receptors. Cell. 48: 549-54. PMID 3028640 DOI: 10.1016/0092-8674(87)90233-9 |
0.355 |
|
| 1987 |
Schwarzbauer JE, Mulligan RC, Hynes RO. Efficient and stable expression of recombinant fibronectin polypeptides. Proceedings of the National Academy of Sciences of the United States of America. 84: 754-8. PMID 3027700 DOI: 10.1073/Pnas.84.3.754 |
0.556 |
|
| 1987 |
Hynes RO, Schwarzbauer JE, Tamkun JW. Isolation and analysis of cDNA and genomic clones of fibronectin and its receptor. Methods in Enzymology. 144: 447-63. PMID 2957568 DOI: 10.1016/0076-6879(87)44194-3 |
0.512 |
|
| 1987 |
DeSimone DW, Stepp MA, Patel RS, Hynes RO. The integrin family of cell surface receptors Biochemical Society Transactions. 15: 789-791. PMID 2826269 DOI: 10.1042/Bst0150789A |
0.614 |
|
| 1987 |
Schwarzbauer JE, Patel RS, Fonda D, Hynes RO. Multiple sites of alternative splicing of the rat fibronectin gene transcript. The Embo Journal. 6: 2573-80. PMID 2445560 DOI: 10.1002/J.1460-2075.1987.Tb02547.X |
0.529 |
|
| 1986 |
Cowin P, Kapprell HP, Franke WW, Tamkun J, Hynes RO. Plakoglobin: a protein common to different kinds of intercellular adhering junctions. Cell. 46: 1063-73. PMID 3530498 DOI: 10.1016/0092-8674(86)90706-3 |
0.358 |
|
| 1986 |
Paul JI, Schwarzbauer JE, Tamkun JW, Hynes RO. Cell-type-specific fibronectin subunits generated by alternative splicing. The Journal of Biological Chemistry. 261: 12258-65. PMID 3528152 |
0.512 |
|
| 1986 |
Tamkun JW, DeSimone DW, Fonda D, Patel RS, Buck C, Horwitz AF, Hynes RO. Structure of integrin, a glycoprotein involved in the transmembrane linkage between fibronectin and actin. Cell. 46: 271-82. PMID 3487386 DOI: 10.1016/0092-8674(86)90744-0 |
0.624 |
|
| 1986 |
Lawler J, Hynes RO. The structure of human thrombospondin, an adhesive glycoprotein with multiple calcium-binding sites and homologies with several different proteins Journal of Cell Biology. 103: 1635-1648. PMID 2430973 DOI: 10.1083/Jcb.103.5.1635 |
0.321 |
|
| 1985 |
Schwarzbauer JE, Paul JI, Hynes RO. On the origin of species of fibronectin. Proceedings of the National Academy of Sciences of the United States of America. 82: 1424-8. PMID 3856272 DOI: 10.1073/Pnas.82.5.1424 |
0.519 |
|
| 1985 |
Gardner JM, Hynes RO. Interaction of fibronectin with its receptor on platelets Cell. 42: 439-448. PMID 2411420 DOI: 10.1016/0092-8674(85)90101-1 |
0.336 |
|
| 1985 |
Price J, Hynes R. Astrocytes in culture synthesize and secrete a variant form of fibronectin The Journal of Neuroscience. 5: 2205-2211. DOI: 10.1523/Jneurosci.05-08-02205.1985 |
0.31 |
|
| 1984 |
Hynes RO, Schwarzbauer JE, Tamkun JW. Fibronectin: a versatile gene for a versatile protein. Ciba Foundation Symposium. 108: 75-92. PMID 6569832 |
0.475 |
|
| 1984 |
Tamkun JW, Schwarzbauer JE, Hynes RO. A single rat fibronectin gene generates three different mRNAs by alternative splicing of a complex exon. Proceedings of the National Academy of Sciences of the United States of America. 81: 5140-4. PMID 6089177 DOI: 10.1073/Pnas.81.16.5140 |
0.495 |
|
| 1983 |
Senger DR, Destree AT, Hynes RO. Complex regulation of fibronectin synthesis by cells in culture. The American Journal of Physiology. 245: C144-50. PMID 6869518 DOI: 10.1152/Ajpcell.1983.245.1.C144 |
0.625 |
|
| 1983 |
Schwarzbauer JE, Tamkun JW, Lemischka IR, Hynes RO. Three different fibronectin mRNAs arise by alternative splicing within the coding region. Cell. 35: 421-31. PMID 6317187 DOI: 10.1016/0092-8674(83)90175-7 |
0.517 |
|
| 1982 |
Lahav J, Schwartz MA, Hynes RO. Analysis of platelet adhesion with a radioactive chemical crosslinking reagent: interaction of thrombospondin with fibronectin and collagen. Cell. 31: 253-62. PMID 7159924 DOI: 10.1016/0092-8674(82)90425-1 |
0.51 |
|
| 1982 |
Schwartz MA, Das OP, Hynes RO. A new radioactive cross-linking reagent for studying the interactions of proteins. The Journal of Biological Chemistry. 257: 2343-9. PMID 7061425 |
0.412 |
|
| 1982 |
Hynes RO, Destree AT, Wagner DD. Relationships between microfilaments, cell-substratum adhesion, and fibronectin. Cold Spring Harbor Symposia On Quantitative Biology. 46: 659-70. PMID 7049533 DOI: 10.1101/Sqb.1982.046.01.062 |
0.555 |
|
| 1982 |
Lahav J, Hynes RO. Involvement of fibronectin, Von Willebrand factor, and fibrinogen in platelet interaction with solid substrata. Journal of Supramolecular Structure and Cellular Biochemistry. 17: 299-311. PMID 6977039 DOI: 10.1002/Jsscb.380170402 |
0.313 |
|
| 1982 |
Wagner DD, Hynes RO. Fibronectin-coated beads are endocytosed by cells and align with microfilament bundles. Experimental Cell Research. 140: 373-81. PMID 6889536 DOI: 10.1016/0014-4827(82)90126-4 |
0.526 |
|
| 1981 |
Van De Water L, Schroeder S, Crenshaw EB, Hynes RO. Phagocytosis of gelatin-latex particles by a murine macrophage line is dependent on fibronectin and heparin Journal of Cell Biology. 90: 32-39. PMID 7251676 DOI: 10.1083/Jcb.90.1.32 |
0.321 |
|
| 1981 |
Mayer BW, Hay ED, Hynes RO. Immunocytochemical localization of fibronectin in embryonic chick trunk and area vasculosa. Developmental Biology. 82: 267-86. PMID 7014292 DOI: 10.1016/0012-1606(81)90451-6 |
0.322 |
|
| 1981 |
Courtoy PJ, Kanwar YS, Hynes RO, Farquhar MG. Fibronectin localization in the rat glomerulus. The Journal of Cell Biology. 87: 691-6. PMID 7007395 DOI: 10.1083/Jcb.87.3.691 |
0.36 |
|
| 1980 |
Senger DR, Wirth DF, Hynes RO. Transformation-specific secreted phosophoproteins. Nature. 286: 619-21. PMID 7402340 DOI: 10.1038/286619A0 |
0.62 |
|
| 1980 |
Senger DR, Wirth DF, Bryant C, Hynes RO. Transformation-specific secreted proteins. Cold Spring Harbor Symposia On Quantitative Biology. 44: 651-7. PMID 6933047 DOI: 10.1101/Sqb.1980.044.01.068 |
0.604 |
|
| 1979 |
Hynes RO, Destree AT, Perkins ME, Wagner DD. Cell surface fibronectin and oncogenic transformation. Journal of Supramolecular Structure. 11: 95-104. PMID 522486 DOI: 10.1002/Jss.400110110 |
0.575 |
|
| 1979 |
Mahdavi V, Hynes RO. Proteolytic enzymes in normal and transformed cells. Biochimica Et Biophysica Acta. 583: 167-78. PMID 444559 DOI: 10.1016/0304-4165(79)90424-0 |
0.322 |
|
| 1979 |
Critchley DR, England MA, Wakely J, Hynes RO. Distribution of fibronectin in the ectoderm of gastrulating chick embryos Nature. 280: 498-500. PMID 379654 DOI: 10.1038/280498A0 |
0.355 |
|
| 1979 |
Hynes RO, Destree AT. Relationships between fibronectin (LETS protein) and actin. Cell. 15: 875-86. PMID 365353 DOI: 10.1016/0092-8674(78)90272-6 |
0.346 |
|
| 1979 |
Graham JM, Hynes RO, Rowlatt C, Sandall JK. Cell surface coat of hamster fibroblasts. Annals of the New York Academy of Sciences. 312: 221-39. PMID 291362 DOI: 10.1111/J.1749-6632.1978.Tb16805.X |
0.346 |
|
| 1979 |
Senger DR, Wirth DF, Hynes RO. Transformed mammalian cells secrete specific proteins and phosphoproteins. Cell. 16: 885-93. PMID 88265 DOI: 10.1016/0092-8674(79)90103-X |
0.632 |
|
| 1978 |
Ali IU, Hynes RO. Effects of LETS glycoprotein on cell motility. Cell. 14: 439-46. PMID 667950 DOI: 10.1016/0092-8674(78)90129-0 |
0.346 |
|
| 1978 |
Ali IU, Hynes RO. Role of disulfide bonds in the attachment and function of large, external, transformation-sensitive glycoprotein at the cell surface. Biochimica Et Biophysica Acta. 510: 140-50. PMID 667030 DOI: 10.1016/0005-2736(78)90136-0 |
0.329 |
|
| 1978 |
Hynes RO, Destree AT, Mautner VM, Ali IU. Synthesis, secretion, and attachment of LETS glycoprotein in normal and transformed cells. Journal of Supramolecular Structure. 7: 397-408. PMID 616487 DOI: 10.1002/Jss.400070311 |
0.363 |
|
| 1978 |
Senger DR, Hynes RO. C3 component of complement secreted by established cell lines. Cell. 15: 375-84. PMID 569023 DOI: 10.1016/0092-8674(78)90006-5 |
0.609 |
|
| 1978 |
Dunham JS, Hynes RO. Differences in the sulfated macromolecules synthesized by normal and transformed hamster fibroblasts. Biochimica Et Biophysica Acta. 506: 242-55. PMID 563729 DOI: 10.1016/0005-2736(78)90395-4 |
0.31 |
|
| 1978 |
Hynes RO, Ali IU, Destree AT, Mautner V, Perkins ME, Senger DR, Wagner DD, Smith KK. A large glycoprotein lost from the surfaces of transformed cells. Annals of the New York Academy of Sciences. 312: 317-42. PMID 386882 DOI: 10.1111/J.1749-6632.1978.Tb16811.X |
0.69 |
|
| 1978 |
Mahdavi V, Hynes RO. Effects of cocultivation with transformed cells on surface proteins of normal cells. Biochimica Et Biophysica Acta. 542: 191-208. PMID 150865 DOI: 10.1016/0304-4165(78)90015-6 |
0.355 |
|
| 1977 |
Ali IU, Mautner V, Lanza R, Hynes RO. Restoration of normal morphology, adhesion and cytoskeleton in transformed cells by addition of a transformation-sensitive surface protein. Cell. 11: 115-26. PMID 326414 DOI: 10.1016/0092-8674(77)90322-1 |
0.359 |
|
| 1977 |
Hynes RO, Destree A. Extensive disulfide bonding at the mammalian cell surface. Proceedings of the National Academy of Sciences of the United States of America. 74: 2855-9. PMID 268636 DOI: 10.1073/Pnas.74.7.2855 |
0.304 |
|
| 1976 |
Hynes RO, Pearistein ES. Investigations of the possible role of proteases in altering surface proteins of virally transformed hamster fibroblasts. Journal of Supramolecular Structure. 4: 1-14. PMID 1256058 DOI: 10.1002/Jss.400040102 |
0.338 |
|
| 1976 |
Hynes RO. Cell surface proteins and malignant transformation. Biochimica Et Biophysica Acta. 458: 73-107. PMID 779852 DOI: 10.1016/0304-419X(76)90015-9 |
0.322 |
|
| 1976 |
Critchley DR, Wyke JA, Hynes RO. Cell surface and metabolic labelling of the proteins of normal and transformed chicken cells. Biochimica Et Biophysica Acta. 436: 335-52. PMID 179596 DOI: 10.1016/0005-2736(76)90198-X |
0.318 |
|
| 1975 |
Hynes RO, Bye JM. Density and cell cycle dependence of cell surface proteins in hamster fibroblasts. Cell. 3: 113-20. PMID 4473270 DOI: 10.1016/0092-8674(74)90114-7 |
0.32 |
|
| 1975 |
Hynes RO, Humphryes KC. Characterization of the external proteins of hamster fibroblasts. The Journal of Cell Biology. 62: 438-48. PMID 4372240 DOI: 10.1083/Jcb.62.2.438 |
0.324 |
|
| 1974 |
Smart JE, Hynes RO. Developmentally regulated cell surface alterations in Dictyostelium discoideum. Nature. 251: 319-321. PMID 4473716 DOI: 10.1038/251319A0 |
0.356 |
|
| 1974 |
Hynes RO. Alteration of cell-surface proteins by viral transformation and by proteolysis. Proceedings of the National Academy of Sciences of the United States of America. 70: 3170-4. PMID 4361679 DOI: 10.1073/Pnas.70.11.3170 |
0.351 |
|
| 1972 |
Hynes RO, Gross PR. Informational RNA sequences in early sea urchin embryos. Biochimica Et Biophysica Acta. 259: 104-11. PMID 5062411 DOI: 10.1016/0005-2787(72)90477-7 |
0.485 |
|
| 1972 |
Hynes RO, Greenhouse GA, Minkoff R, Gross PR. Properties of the three cell types in sixteen-cell sea urchin embryos: RNA synthesis. Developmental Biology. 27: 457-78. PMID 5029494 DOI: 10.1016/0012-1606(72)90186-8 |
0.543 |
|
| 1972 |
Hynes RO, Raff RA, Gross PR. Properties of the three cell types in sixteen-cell sea urchin embryos: aggregation and microtuble protein synthesis. Developmental Biology. 27: 150-64. PMID 5019934 DOI: 10.1016/0012-1606(72)90094-2 |
0.686 |
|
| 1971 |
Greenhouse GA, Hynes RO, Gross PR. Sea urchin embryos are permeable to actinomycin. Science (New York, N.Y.). 171: 686-9. PMID 5540310 DOI: 10.1126/Science.171.3972.686 |
0.51 |
|
| 1970 |
Hynes RO, Gross PR. A method for separating cells from early sea urchin embryos. Developmental Biology. 21: 383-402. PMID 5436900 DOI: 10.1016/0012-1606(70)90131-4 |
0.547 |
|
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