Kenneth B. Margulies

Bioengineering University of Pennsylvania, Philadelphia, PA, United States 
Biomedical Engineering
"Kenneth Margulies"
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Jani V, Aslam MI, Fenwick AJ, et al. (2023) Right Ventricular Sarcomere Contractile Depression and the Role of Thick Filament Activation in Human Heart Failure with Pulmonary Hypertension. Biorxiv : the Preprint Server For Biology
Ozcan M, Guo Z, Valenzuela Ripoll C, et al. (2023) Sustained alternate-day fasting potentiates doxorubicin cardiotoxicity. Cell Metabolism
Hahn VS, Petucci C, Kim MS, et al. (2023) Myocardial Metabolomics of Human Heart Failure With Preserved Ejection Fraction. Circulation
Simonson B, Chaffin M, Hill MC, et al. (2023) Single-nucleus RNA sequencing in ischemic cardiomyopathy reveals common transcriptional profile underlying end-stage heart failure. Cell Reports. 42: 112086
Nollet EE, Duursma I, Rozenbaum A, et al. (2023) Mitochondrial dysfunction in human hypertrophic cardiomyopathy is linked to cardiomyocyte architecture disruption and corrected by improving NADH-driven mitochondrial respiration. European Heart Journal
Flam E, Jang C, Murashige D, et al. (2022) Integrated landscape of cardiac metabolism in end-stage human nonischemic dilated cardiomyopathy. Nature Cardiovascular Research. 1: 817-829
Levin MG, Tsao NL, Singhal P, et al. (2022) Genome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure. Nature Communications. 13: 6914
Murashige D, Jung JW, Neinast MD, et al. (2022) Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure. Cell Metabolism
Spurrell CH, Barozzi I, Kosicki M, et al. (2022) Genome-wide fetalization of enhancer architecture in heart disease. Cell Reports. 40: 111400
Margulies KB. (2022) DELIVERing Progress in Heart Failure with Preserved Ejection Fraction. The New England Journal of Medicine
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