Themis R. Kyriakides - Publications

Affiliations: 
Biomedical Engineering Yale University, New Haven, CT 

94 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Liu B, Zhou H, Zhang T, Gao X, Tao B, Xing H, Zhuang Z, Dardik A, Kyriakides TR, Goodwin JE. Loss of endothelial glucocorticoid receptor promotes angiogenesis via upregulation of Wnt/β-catenin pathway. Angiogenesis. PMID 33650028 DOI: 10.1007/s10456-021-09773-x  0.4
2020 Dash BC, Duan K, Xing H, Kyriakides TR, Hsia HC. An In situ Collagen-HA Hydrogel System Promotes Survival and Preserves the Proangiogenic Secretion of hiPSC-derived Vascular Smooth Muscle Cells. Biotechnology and Bioengineering. PMID 32770746 DOI: 10.1002/bit.27530  0.4
2019 Kunkemoeller B, Bancroft T, Xing H, Morris AH, Luciano AK, Wu J, Fernandez-Hernando C, Kyriakides TR. Elevated Thrombospondin-2 Contributes to Delayed Wound Healing in Diabetes. Diabetes. PMID 31391172 DOI: 10.2337/db18-1001  0.96
2019 Xing H, Lee H, Luo L, Kyriakides TR. Extracellular matrix-derived biomaterials in engineering cell function. Biotechnology Advances. 107421. PMID 31381963 DOI: 10.1016/j.biotechadv.2019.107421  0.4
2019 Calabro NE, Barrett A, Chamorro-Jorganes A, Tam S, Kristofik NJ, Xing H, Loye AM, Sessa WC, Hansen K, Kyriakides TR. Thrombospondin-2 regulates extracellular matrix production, LOX levels, and cross-linking via downregulation of miR-29. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 30876926 DOI: 10.1016/j.matbio.2019.03.002  0.4
2018 Xie Y, Ostriker AC, Jin Y, Hu H, Sizer AJ, Peng G, Morris AH, Ryu C, Herzog EL, Kyriakides T, Zhao H, Dardik A, Yu J, Hwa J, Martin KA. LMO7 is a Negative Feedback Regulator of TGF-β Signaling and Fibrosis. Circulation. PMID 30586711 DOI: 10.1161/CIRCULATIONAHA.118.034615  0.96
2018 Morris AH, Lee H, Xing H, Stamer DK, Tan M, Kyriakides TR. Tunable hydrogels derived from genetically engineered extracellular matrix accelerate diabetic wound healing. Acs Applied Materials & Interfaces. PMID 30424595 DOI: 10.1021/acsami.8b08920  0.96
2018 Shayan M, Padmanabhan J, Morris AH, Cheung B, Smith R, Schroers J, Kyriakides TR. Nanopatterned Bulk Metallic Glass-based Biomaterials Modulate Macrophage Polarization. Acta Biomaterialia. PMID 29859902 DOI: 10.1016/j.actbio.2018.05.051  0.96
2018 Morris AH, Stamer DK, Kunkemoeller B, Chang J, Xing H, Kyriakides TR. Decellularized materials derived from TSP2-KO mice promote enhanced neovascularization and integration in diabetic wounds. Biomaterials. 169: 61-71. PMID 29631168 DOI: 10.1016/j.biomaterials.2018.03.049  0.96
2017 Kunkemoeller B, Kyriakides TR. Redox Signaling in Diabetic Wound Healing Regulates Extracellular Matrix Deposition. Antioxidants & Redox Signaling. PMID 28699352 DOI: 10.1089/ars.2017.7263  0.44
2017 Morris AH, Mahal RS, Udell J, Wu M, Kyriakides TR. Multicompartment Drug Release System for Dynamic Modulation of Tissue Responses. Advanced Healthcare Materials. PMID 28636088 DOI: 10.1002/adhm.201700370  0.96
2016 Padmanabhan J, Augelli MJ, Cheung B, Kinser ER, Cleary B, Kumar P, Wang R, Sawyer AJ, Li R, Schwarz UD, Schroers J, Kyriakides TR. Regulation of cell-cell fusion by nanotopography. Scientific Reports. 6: 33277. PMID 27615159 DOI: 10.1038/srep33277  1
2016 Morris AH, Chang J, Kyriakides TR. Inadequate Processing of Decellularized Dermal Matrix Reduces Cell Viability In Vitro and Increases Apoptosis and Acute Inflammation In Vivo. Bioresearch Open Access. 5: 177-87. PMID 27500014 DOI: 10.1089/biores.2016.0021  0.96
2016 Liu Y, Padmanabhan J, Cheung B, Liu J, Chen Z, Scanley BE, Wesolowski D, Pressley M, Broadbridge CC, Altman S, Schwarz UD, Kyriakides TR, Schroers J. Combinatorial development of antibacterial Zr-Cu-Al-Ag thin film metallic glasses. Scientific Reports. 6: 26950. PMID 27230692 DOI: 10.1038/srep26950  1
2016 Moore LB, Sawyer AJ, Saucier-Sawyer J, Saltzman WM, Kyriakides TR. Nanoparticle delivery of miR-223 to attenuate macrophage fusion. Biomaterials. 89: 127-135. PMID 26967647 DOI: 10.1016/j.biomaterials.2016.02.036  1
2016 Sawyer AJ, Kyriakides TR. Matricellular proteins in drug delivery: Therapeutic targets, active agents, and therapeutic localization. Advanced Drug Delivery Reviews. PMID 26763408 DOI: 10.1016/j.addr.2015.12.016  1
2015 Moore LB, Kyriakides TR. Molecular Characterization of Macrophage-Biomaterial Interactions. Advances in Experimental Medicine and Biology. 865: 109-22. PMID 26306446 DOI: 10.1007/978-3-319-18603-0_7  1
2015 D'Alessio A, Moccia F, Li JH, Micera A, Kyriakides TR. Angiogenesis and Vasculogenesis in Health and Disease. Biomed Research International. 2015: 126582. PMID 26171386 DOI: 10.1155/2015/126582  1
2015 Papanna R, Mann LK, Tseng SC, Stewart RJ, Kaur SS, Swindle MM, Kyriakides TR, Tatevian N, Moise KJ. Cryopreserved human amniotic membrane and a bioinspired underwater adhesive to seal and promote healing of iatrogenic fetal membrane defect sites. Placenta. PMID 26059341 DOI: 10.1016/j.placenta.2015.05.015  1
2015 Papanna R, Mann LK, Moise KJ, Kyriakides T, Johnson A, Garcia E, Buhimschi CS, Buhimschi IA. Histologic changes of the fetal membranes after fetoscopic laser surgery for twin-twin transfusion syndrome. Pediatric Research. PMID 26020146 DOI: 10.1038/pr.2015.105  1
2015 Swartzlander MD, Blakney AK, Amer LD, Hankenson KD, Kyriakides TR, Bryant SJ. Immunomodulation by mesenchymal stem cells combats the foreign body response to cell-laden synthetic hydrogels. Biomaterials. 41: 79-88. PMID 25522967 DOI: 10.1016/j.biomaterials.2014.11.020  1
2015 Swartzlander MD, Barnes CA, Blakney AK, Kaar JL, Kyriakides TR, Bryant SJ. Linking the foreign body response and protein adsorption to PEG-based hydrogels using proteomics. Biomaterials. 41: 26-36. PMID 25522962 DOI: 10.1016/j.biomaterials.2014.11.026  1
2015 Dimitrievska S, Cai C, Weyers A, Balestrini JL, Lin T, Sundaram S, Hatachi G, Spiegel DA, Kyriakides TR, Miao J, Li G, Niklason LE, Linhardt RJ. Click-coated, heparinized, decellularized vascular grafts. Acta Biomaterialia. 13: 177-87. PMID 25463496 DOI: 10.1016/j.actbio.2014.11.015  1
2015 Padmanabhan J, Kyriakides TR. Nanomaterials, inflammation, and tissue engineering. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. 7: 355-70. PMID 25421333 DOI: 10.1002/wnan.1320  1
2015 Bancroft T, Bouaouina M, Roberts S, Lee M, Calderwood DA, Schwartz M, Simons M, Sessa WC, Kyriakides TR. Up-regulation of thrombospondin-2 in Akt1-null mice contributes to compromised tissue repair due to abnormalities in fibroblast function. The Journal of Biological Chemistry. 290: 409-22. PMID 25389299 DOI: 10.1074/jbc.M114.618421  1
2015 Moore LB, Sawyer AJ, Charokopos A, Skokos EA, Kyriakides TR. Loss of monocyte chemoattractant protein-1 alters macrophage polarization and reduces NFκB activation in the foreign body response. Acta Biomaterialia. 11: 37-47. PMID 25242651 DOI: 10.1016/j.actbio.2014.09.022  1
2014 Lee MY, Luciano AK, Ackah E, Rodriguez-Vita J, Bancroft TA, Eichmann A, Simons M, Kyriakides TR, Morales-Ruiz M, Sessa WC. Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates. Proceedings of the National Academy of Sciences of the United States of America. 111: 12865-70. PMID 25136137 DOI: 10.1073/pnas.1408472111  1
2014 Sawyer AJ, Tian W, Saucier-Sawyer JK, Rizk PJ, Saltzman WM, Bellamkonda RV, Kyriakides TR. The effect of inflammatory cell-derived MCP-1 loss on neuronal survival during chronic neuroinflammation. Biomaterials. 35: 6698-706. PMID 24881026 DOI: 10.1016/j.biomaterials.2014.05.008  1
2014 Padmanabhan J, Kinser ER, Stalter MA, Duncan-Lewis C, Balestrini JL, Sawyer AJ, Schroers J, Kyriakides TR. Engineering cellular response using nanopatterned bulk metallic glass. Acs Nano. 8: 4366-75. PMID 24724817 DOI: 10.1021/nn501874q  1
2014 Morris AH, Kyriakides TR. Matricellular proteins and biomaterials. Matrix Biology : Journal of the International Society For Matrix Biology. 37: 183-91. PMID 24657843 DOI: 10.1016/j.matbio.2014.03.002  1
2014 Calabro NE, Kristofik NJ, Kyriakides TR. Thrombospondin-2 and extracellular matrix assembly. Biochimica Et Biophysica Acta. 1840: 2396-402. PMID 24440155 DOI: 10.1016/j.bbagen.2014.01.013  1
2014 Ju R, Zhuang ZW, Zhang J, Lanahan AA, Kyriakides T, Sessa WC, Simons M. Angiopoietin-2 secretion by endothelial cell exosomes: Regulation by the phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial nitric oxide synthase (eNOS) and syndecan-4/syntenin pathways Journal of Biological Chemistry. 289: 510-519. PMID 24235146 DOI: 10.1074/jbc.M113.506899  1
2013 Sawyer AJ, Wesolowski D, Gandotra N, Stojadinovic A, Izadjoo M, Altman S, Kyriakides TR. A peptide-morpholino oligomer conjugate targeting Staphylococcus aureus gyrA mRNA improves healing in an infected mouse cutaneous wound model. International Journal of Pharmaceutics. 453: 651-5. PMID 23727592 DOI: 10.1016/j.ijpharm.2013.05.041  1
2013 Kobsa S, Kristofik NJ, Sawyer AJ, Bothwell AL, Kyriakides TR, Saltzman WM. An electrospun scaffold integrating nucleic acid delivery for treatment of full-thickness wounds. Biomaterials. 34: 3891-901. PMID 23453058 DOI: 10.1016/j.biomaterials.2013.02.016  1
2013 Sawyer AJ, Kyriakides TR. Nanoparticle-based evaluation of blood-brain barrier leakage during the foreign body response. Journal of Neural Engineering. 10: 016013. PMID 23337399 DOI: 10.1088/1741-2560/10/1/016013  1
2013 Swartzlander MD, Lynn AD, Blakney AK, Kyriakides TR, Bryant SJ. Understanding the host response to cell-laden poly(ethylene glycol)-based hydrogels. Biomaterials. 34: 952-64. PMID 23149012 DOI: 10.1016/j.biomaterials.2012.10.037  1
2013 Saltzman WM, Kyriakides TR. Cell Interactions with Polymers Principles of Tissue Engineering: Fourth Edition. 385-406. DOI: 10.1016/B978-0-12-398358-9.00020-3  1
2011 Malik AF, Hoque R, Ouyang X, Ghani A, Hong E, Khan K, Moore LB, Ng G, Munro F, Flavell RA, Shi Y, Kyriakides TR, Mehal WZ. Inflammasome components Asc and caspase-1 mediate biomaterial-induced inflammation and foreign body response. Proceedings of the National Academy of Sciences of the United States of America. 108: 20095-100. PMID 22109549 DOI: 10.1073/pnas.1105152108  1
2011 MacLauchlan S, Yu J, Parrish M, Asoulin TA, Schleicher M, Krady MM, Zeng J, Huang PL, Sessa WC, Kyriakides TR. Endothelial nitric oxide synthase controls the expression of the angiogenesis inhibitor thrombospondin 2. Proceedings of the National Academy of Sciences of the United States of America. 108: E1137-45. PMID 21949402 DOI: 10.1073/pnas.1104357108  1
2011 Hibino N, Yi T, Duncan DR, Rathore A, Dean E, Naito Y, Dardik A, Kyriakides T, Madri J, Pober JS, Shinoka T, Breuer CK. A critical role for macrophages in neovessel formation and the development of stenosis in tissue-engineered vascular grafts. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 4253-63. PMID 21865316 DOI: 10.1096/fj.11-186585  1
2011 Tian W, Sawyer A, Kocaoglu FB, Kyriakides TR. Astrocyte-derived thrombospondin-2 is critical for the repair of the blood-brain barrier. The American Journal of Pathology. 179: 860-8. PMID 21704005 DOI: 10.1016/j.ajpath.2011.05.002  1
2011 Liu J, Jiang Z, Zhang S, Liu C, Gross RA, Kyriakides TR, Saltzman WM. Biodegradation, biocompatibility, and drug delivery in poly(ω-pentadecalactone-co-p-dioxanone) copolyesters. Biomaterials. 32: 6646-54. PMID 21641030 DOI: 10.1016/j.biomaterials.2011.05.046  1
2011 Hibino N, Villalona G, Pietris N, Duncan DR, Schoffner A, Roh JD, Yi T, Dobrucki LW, Mejias D, Sawh-Martinez R, Harrington JK, Sinusas A, Krause DS, Kyriakides T, Saltzman WM, et al. Tissue-engineered vascular grafts form neovessels that arise from regeneration of the adjacent blood vessel. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2731-9. PMID 21566209 DOI: 10.1096/fj.11-182246  1
2011 Skokos EA, Charokopos A, Khan K, Wanjala J, Kyriakides TR. Lack of TNF-α-induced MMP-9 production and abnormal E-cadherin redistribution associated with compromised fusion in MCP-1-null macrophages. The American Journal of Pathology. 178: 2311-21. PMID 21514443 DOI: 10.1016/j.ajpath.2011.01.045  1
2011 Lynn AD, Blakney AK, Kyriakides TR, Bryant SJ. Temporal progression of the host response to implanted poly(ethylene glycol)-based hydrogels. Journal of Biomedical Materials Research. Part A. 96: 621-31. PMID 21268236 DOI: 10.1002/jbm.a.33015  1
2010 Zhou J, Tang PC, Qin L, Gayed PM, Li W, Skokos EA, Kyriakides TR, Pober JS, Tellides G. CXCR3-dependent accumulation and activation of perivascular macrophages is necessary for homeostatic arterial remodeling to hemodynamic stresses. The Journal of Experimental Medicine. 207: 1951-66. PMID 20733031 DOI: 10.1084/jem.20100098  1
2010 Roh JD, Sawh-Martinez R, Brennan MP, Jay SM, Devine L, Rao DA, Yi T, Mirensky TL, Nalbandian A, Udelsman B, Hibino N, Shinoka T, Saltzman WM, Snyder E, Kyriakides TR, et al. Tissue-engineered vascular grafts transform into mature blood vessels via an inflammation-mediated process of vascular remodeling. Proceedings of the National Academy of Sciences of the United States of America. 107: 4669-74. PMID 20207947 DOI: 10.1073/pnas.0911465107  1
2010 Jay SM, Shepherd BR, Andrejecsk JW, Kyriakides TR, Pober JS, Saltzman WM. Dual delivery of VEGF and MCP-1 to support endothelial cell transplantation for therapeutic vascularization. Biomaterials. 31: 3054-62. PMID 20110124 DOI: 10.1016/j.biomaterials.2010.01.014  1
2010 Lynn AD, Kyriakides TR, Bryant SJ. Characterization of the in vitro macrophage response and in vivo host response to poly(ethylene glycol)-based hydrogels. Journal of Biomedical Materials Research. Part A. 93: 941-53. PMID 19708075 DOI: 10.1002/jbm.a.32595  1
2010 Jay SM, Skokos EA, Zeng J, Knox K, Kyriakides TR. Macrophage fusion leading to foreign body giant cell formation persists under phagocytic stimulation by microspheres in vitro and in vivo in mouse models. Journal of Biomedical Materials Research. Part A. 93: 189-99. PMID 19536825 DOI: 10.1002/jbm.a.32513  1
2010 Sullivan JC, Kakati DD, Carter E, Boyd AK, Kyriakides TR, Azin Agah A. Elevated expression of isopeptide bond cross-links contributes to fibrosis in scleroderma and the healing wounds of tight skin mice (Wound Repair and Regeneration (2008) 16:5 (699-705) DOI: 10.1111/j.1524-475x.2008.00420.x) Wound Repair and Regeneration. 18: 550. DOI: 10.1111/j.1524-475X.2010.00622.x  1
2009 Kyriakides TR, Maclauchlan S. The role of thrombospondins in wound healing, ischemia, and the foreign body reaction. Journal of Cell Communication and Signaling. 3: 215-25. PMID 19844806 DOI: 10.1007/s12079-009-0077-z  1
2009 Yu J, Fernández-Hernando C, Suarez Y, Schleicher M, Hao Z, Wright PL, DiLorenzo A, Kyriakides TR, Sessa WC. Reticulon 4B (Nogo-B) is necessary for macrophage infiltration and tissue repair. Proceedings of the National Academy of Sciences of the United States of America. 106: 17511-6. PMID 19805174 DOI: 10.1073/pnas.0907359106  1
2009 Kyriakides TR, Wulsin D, Skokos EA, Fleckman P, Pirrone A, Shipley JM, Senior RM, Bornstein P. Mice that lack matrix metalloproteinase-9 display delayed wound healing associated with delayed reepithelization and disordered collagen fibrillogenesis. Matrix Biology : Journal of the International Society For Matrix Biology. 28: 65-73. PMID 19379668 DOI: 10.1016/j.matbio.2009.01.001  1
2009 Lin SP, Kyriakides TR, Chen JJ. On-line observation of cell growth in a three-dimensional matrix on surface-modified microelectrode arrays. Biomaterials. 30: 3110-7. PMID 19344948 DOI: 10.1016/j.biomaterials.2009.03.017  1
2009 Tian W, Kyriakides TR. Matrix metalloproteinase-9 deficiency leads to prolonged foreign body response in the brain associated with increased IL-1beta levels and leakage of the blood-brain barrier. Matrix Biology : Journal of the International Society For Matrix Biology. 28: 148-59. PMID 19264129 DOI: 10.1016/j.matbio.2009.02.002  1
2009 MacLauchlan S, Skokos EA, Meznarich N, Zhu DH, Raoof S, Shipley JM, Senior RM, Bornstein P, Kyriakides TR. Macrophage fusion, giant cell formation, and the foreign body response require matrix metalloproteinase 9. Journal of Leukocyte Biology. 85: 617-26. PMID 19141565 DOI: 10.1189/jlb.1008588  1
2009 Maclauchlan S, Skokos EA, Agah A, Zeng J, Tian W, Davidson JM, Bornstein P, Kyriakides TR. Enhanced angiogenesis and reduced contraction in thrombospondin-2-null wounds is associated with increased levels of matrix metalloproteinases-2 and -9, and soluble VEGF. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 57: 301-13. PMID 19029404 DOI: 10.1369/jhc.2008.952689  1
2009 Tian W, Kyriakides TR. Thrombospondin 2-null mice display an altered brain foreign body response to polyvinyl alcohol sponge implants. Biomedical Materials (Bristol, England). 4: 015010. PMID 19020342 DOI: 10.1088/1748-6041/4/1/015010  1
2009 Jay SM, Shepherd BR, Andrejecsk JW, Kyriakides TR, Pober JS, Saltzman WM. Engineered molecular delivery for control and enhancement of transplanted endothelial cell fate in tissue engineering Bioengineering, Proceedings of the Northeast Conference. DOI: 10.1109/NEBC.2009.4967788  1
2009 Schroers J, Kumar G, Hodges TM, Chan S, Kyriakides TR. Bulk metallic glasses for biomedical applications Jom. 61: 21-29. DOI: 10.1007/s11837-009-0128-1  1
2008 Sullivan JC, Kakati DD, Carter E, Boyd AK, Kyriakides TR, Agah A. Elevated expression of isopeptide bond cross-links contributes to fibrosis in scleroderma and the healing wounds of tight skin mice. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 16: 699-705. PMID 19128265 DOI: 10.1111/j.1524-475X.2008.00420.x  1
2008 Helming L, Tomasello E, Kyriakides TR, Martinez FO, Takai T, Gordon S, Vivier E. Essential role of DAP12 signaling in macrophage programming into a fusion-competent state. Science Signaling. 1: ra11. PMID 18957693 DOI: 10.1126/scisignal.1159665  1
2008 Cahn F, Kyriakides TR. Generation of an artificial skin construct containing a non-degradable fiber mesh: a potential transcutaneous interface. Biomedical Materials (Bristol, England). 3: 034110. PMID 18689926 DOI: 10.1088/1748-6041/3/3/034110  1
2008 Krady MM, Zeng J, Yu J, MacLauchlan S, Skokos EA, Tian W, Bornstein P, Sessa WC, Kyriakides TR. Thrombospondin-2 modulates extracellular matrix remodeling during physiological angiogenesis. The American Journal of Pathology. 173: 879-91. PMID 18688033 DOI: 10.2353/ajpath.2008.080128  1
2008 Roh JD, Nelson GN, Brennan MP, Mirensky TL, Yi T, Hazlett TF, Tellides G, Sinusas AJ, Pober JS, Saltzman WM, Kyriakides TR, Breuer CK. Small-diameter biodegradable scaffolds for functional vascular tissue engineering in the mouse model. Biomaterials. 29: 1454-63. PMID 18164056 DOI: 10.1016/j.biomaterials.2007.11.041  1
2007 Jay SM, Skokos E, Laiwalla F, Krady MM, Kyriakides TR. Foreign body giant cell formation is preceded by lamellipodia formation and can be attenuated by inhibition of Rac1 activation. The American Journal of Pathology. 171: 632-40. PMID 17556592 DOI: 10.2353/ajpath.2007.061213  1
2007 Kyriakides TR. Thrombospondin says no to NO Blood. 109: 1793.  1
2006 Bryers JD, Jarvis RA, Lebo J, Prudencio A, Kyriakides TR, Uhrich K. Biodegradation of poly(anhydride-esters) into non-steroidal anti-inflammatory drugs and their effect on Pseudomonas aeruginosa biofilms in vitro and on the foreign-body response in vivo. Biomaterials. 27: 5039-48. PMID 16777217 DOI: 10.1016/j.biomaterials.2006.05.034  1
2005 Agah A, Kyriakides TR, Bornstein P. Proteolysis of cell-surface tissue transglutaminase by matrix metalloproteinase-2 contributes to the adhesive defect and matrix abnormalities in thrombospondin-2-null fibroblasts and mice. The American Journal of Pathology. 167: 81-8. PMID 15972954 DOI: 10.1016/S0002-9440(10)62955-0  1
2005 Puolakkainen PA, Bradshaw AD, Brekken RA, Reed MJ, Kyriakides T, Funk SE, Gooden MD, Vernon RB, Wight TN, Bornstein P, Sage EH. SPARC-thrombospondin-2-double-null mice exhibit enhanced cutaneous wound healing and increased fibrovascular invasion of subcutaneous polyvinyl alcohol sponges. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 53: 571-81. PMID 15872050 DOI: 10.1369/jhc.4A6425.2005  1
2004 Kyriakides TR, Foster MJ, Keeney GE, Tsai A, Giachelli CM, Clark-Lewis I, Rollins BJ, Bornstein P. The CC chemokine ligand, CCL2/MCP1, participates in macrophage fusion and foreign body giant cell formation. The American Journal of Pathology. 165: 2157-66. PMID 15579457 DOI: 10.1016/S0002-9440(10)63265-8  1
2004 Bornstein P, Agah A, Kyriakides TR. The role of thrombospondins 1 and 2 in the regulation of cell-matrix interactions, collagen fibril formation, and the response to injury. The International Journal of Biochemistry & Cell Biology. 36: 1115-25. PMID 15094126 DOI: 10.1016/j.biocel.2004.01.012  1
2004 Agah A, Kyriakides TR, Letrondo N, Björkblom B, Bornstein P. Thrombospondin 2 levels are increased in aged mice: consequences for cutaneous wound healing and angiogenesis. Matrix Biology : Journal of the International Society For Matrix Biology. 22: 539-47. PMID 14996433 DOI: 10.1016/j.matbio.2003.09.004  1
2003 Kyriakides TR, Bornstein P. Matricellular proteins as modulators of wound healing and the foreign body response. Thrombosis and Haemostasis. 90: 986-92. PMID 14652628 DOI: 10.1267/THRO03060986  1
2003 Kyriakides TR, Rojnuckarin P, Reidy MA, Hankenson KD, Papayannopoulou T, Kaushansky K, Bornstein P. Megakaryocytes require thrombospondin-2 for normal platelet formation and function. Blood. 101: 3915-23. PMID 12732502 DOI: 10.1182/blood.V101.10.3915  1
2003 Puolakkainen P, Bradshaw AD, Kyriakides TR, Reed M, Brekken R, Wight T, Bornstein P, Ratner B, Sage EH. Compromised production of extracellular matrix in mice lacking secreted protein, acidic and rich in cysteine (SPARC) leads to a reduced foreign body reaction to implanted biomaterials. The American Journal of Pathology. 162: 627-35. PMID 12547720 DOI: 10.1016/S0002-9440(10)63856-4  1
2002 Agah A, Kyriakides TR, Lawler J, Bornstein P. The lack of thrombospondin-1 (TSP1) dictates the course of wound healing in double-TSP1/TSP2-null mice. The American Journal of Pathology. 161: 831-9. PMID 12213711 DOI: 10.1016/S0002-9440(10)64243-5  1
2002 Lange-Asschenfeldt B, Weninger W, Velasco P, Kyriakides TR, von Andrian UH, Bornstein P, Detmar M. Increased and prolonged inflammation and angiogenesis in delayed-type hypersensitivity reactions elicited in the skin of thrombospondin-2--deficient mice. Blood. 99: 538-45. PMID 11781236 DOI: 10.1182/blood.V99.2.538  1
2002 Kyriakides TR, Cheung CY, Murthy N, Bornstein P, Stayton PS, Hoffman AS. pH-sensitive polymers that enhance intracellular drug delivery in vivo. Journal of Controlled Release : Official Journal of the Controlled Release Society. 78: 295-303. PMID 11772470 DOI: 10.1016/S0168-3659(01)00504-1  1
2002 Hoffman AS, Stayton PS, Press O, Murthy N, Lackey CA, Cheung C, Black F, Campbell J, Fausto N, Kyriakides TR, Bornstein P. Design of "smart" Polymers that can direct intracellular drug delivery Polymers For Advanced Technologies. 13: 992-999.  1
2001 Kyriakides TR, Zhu YH, Yang Z, Huynh G, Bornstein P. Altered extracellular matrix remodeling and angiogenesis in sponge granulomas of thrombospondin 2-null mice American Journal of Pathology. 159: 1255-1262. PMID 11583953  1
2001 Kyriakides TR, Hartzel T, Huynh G, Bornstein P. Regulation of angiogenesis and matrix remodeling by localized, matrix-mediated antisense gene delivery Molecular Therapy. 3: 842-849. PMID 11407897 DOI: 10.1006/mthe.2001.0336  1
2001 Hawighorst T, Velasco P, Streit M, Hong YK, Kyriakides TR, Brown LF, Bornstein P, Detmar M. Thrombospondin-2 plays a protective role in multistep carcinogenesis: a novel host anti-tumor defense mechanism. The Embo Journal. 20: 2631-40. PMID 11387198 DOI: 10.1093/emboj/20.11.2631  1
2001 Hoffman AS, Stayton PS, Press O, Murthy N, Lackey CA, Cheung C, Black F, Campbell J, Fausto N, Kyriakides TR, Bornstein P. Bioinspired polymers that control intracellular drug delivery Biotechnology and Bioprocess Engineering. 6: 205-212.  1
2000 Bornstein P, Kyriakides TR, Yang Z, Armstrong LC, Birk DE. Thrombospondin 2 modulates collagen fibrillogenesis and angiogenesis Journal of Investigative Dermatology Symposium Proceedings. 5: 61-66. PMID 11147677 DOI: 10.1046/j.1087-0024.2000.00005.x  1
2000 Bornstein P, Armstrong LC, Hankenson KD, Kyriakides TR, Yang Z. Thrombospondin 2, a matricellular protein with diverse functions Matrix Biology. 19: 557-568. PMID 11102746 DOI: 10.1016/S0945-053X(00)00104-9  1
2000 Yang Z, Kyriakides TR, Bornstein P. Matricellular proteins as modulators of cell-matrix interactions: Adhesive defect in thrombospondin 2-null fibroblasts is a consequence of increased levels of matrix metalloproteinase-2 Molecular Biology of the Cell. 11: 3353-3364. PMID 11029041  1
2000 Hankenson KD, Bain SD, Kyriakides TR, Smith EA, Goldstein SA, Bornstein P. Increased marrow-derived osteoprogenitor cells and endosteal bone formation in mice lacking thrombospondin 2 Journal of Bone and Mineral Research. 15: 851-862. PMID 10804014  1
1999 Kyriakides TR, Tam JWY, Bornstein P. Accelerated wound healing in mice with a disruption of the thrombospondin 2 gene Journal of Investigative Dermatology. 113: 782-787. PMID 10571734 DOI: 10.1046/j.1523-1747.1999.00755.x  1
1999 Kyriakides TR, Leach KJ, Hoffman AS, Ratner BD, Bornstein P. Mice that lack the angiogenesis inhibitor, thrombospondin 2, mount an altered foreign body reaction characterized by increased vascularity. Proceedings of the National Academy of Sciences of the United States of America. 96: 4449-54. PMID 10200282 DOI: 10.1073/pnas.96.8.4449  1
1998 Kyriakides TR, Zhu YH, Yang Z, Bornstein P. The distribution of the matricellular protein thrombospondin 2 in tissues of embryonic and adult mice Journal of Histochemistry and Cytochemistry. 46: 1007-1015. PMID 9705966  1
1998 Kyriakides TR, Zhu YH, Smith LT, Bain SD, Yang Z, Lin MT, Danielson KG, Iozzo RV, LaMarca M, McKinney CE, Ginns EI, Bornstein P. Mice that lack thrombospondin 2 display connective tissue abnormalities that are associated with disordered collagen fibrillogenesis, an increased vascular density, and a bleeding diathesis Journal of Cell Biology. 140: 419-430. PMID 9442117 DOI: 10.1083/jcb.140.2.419  1
1995 Kyriakides TR, McKillip JL, Spence KD. Biochemical characterization, developmental expression, and induction of the immune protein scolexin from Manduca sexta Archives of Insect Biochemistry and Physiology. 29: 269-280. PMID 7544652  1
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