| Year |
Citation |
Score |
| 2023 |
Sonavane P, Willert K. Wnt signaling and the regulation of pluripotency. Current Topics in Developmental Biology. 153: 95-119. PMID 36967203 DOI: 10.1016/bs.ctdb.2023.01.002 |
0.486 |
|
| 2021 |
Sonavane PR, Willert K. Controlling Wnt Signaling Specificity and Implications for Targeting WNTs Pharmacologically. Handbook of Experimental Pharmacology. PMID 34463853 DOI: 10.1007/164_2021_529 |
0.324 |
|
| 2020 |
Gumber D, Do M, Suresh Kumar N, Sonavane PR, Wu CCN, Cruz LS, Grainger S, Carson D, Gaasterland T, Willert K. Selective activation of FZD7 promotes mesendodermal differentiation of human pluripotent stem cells. Elife. 9. PMID 33331818 DOI: 10.7554/eLife.63060 |
0.467 |
|
| 2019 |
Grainger S, Nguyen N, Richter J, Setayesh J, Lonquich B, Oon CH, Wozniak JM, Barahona R, Kamei CN, Houston J, Carrillo-Terrazas M, Drummond IA, Gonzalez D, Willert K, Traver D. EGFR is required for Wnt9a-Fzd9b signalling specificity in haematopoietic stem cells. Nature Cell Biology. PMID 31110287 DOI: 10.1038/S41556-019-0330-5 |
0.591 |
|
| 2019 |
Willert K, Ho HH, Liebner S. Decision letter: Molecular determinants in Frizzled, Reck, and Wnt7a for ligand-specific signaling in neurovascular development Elife. DOI: 10.7554/Elife.47300.015 |
0.33 |
|
| 2018 |
Grainger S, Willert K. Mechanisms of Wnt signaling and control. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. e1422. PMID 29600540 DOI: 10.1002/Wsbm.1422 |
0.567 |
|
| 2018 |
Grainger S, Traver D, Willert K. Wnt Signaling in Hematological Malignancies. Progress in Molecular Biology and Translational Science. 153: 321-341. PMID 29389522 DOI: 10.1016/Bs.Pmbts.2017.11.002 |
0.452 |
|
| 2018 |
Richter J, Stanley EG, Ng ES, Elefanty AG, Traver D, Willert K. WNT9A Is a Conserved Regulator of Hematopoietic Stem and Progenitor Cell Development. Genes. 9. PMID 29382179 DOI: 10.3390/Genes9020066 |
0.596 |
|
| 2018 |
Grainger S, Wozniak J, Gonzalez D, Willert K, Traver D. Specific Wnt-Fzd Interactions are Required for Hematopoietic Stem Cell Development Experimental Hematology. 64: S68. DOI: 10.1016/J.Exphem.2018.06.234 |
0.527 |
|
| 2017 |
Huggins IJ, Bos T, Gaylord O, Jessen C, Lonquich B, Puranen A, Richter J, Rossdam C, Brafman D, Gaasterland T, Willert K. The WNT target SP5 negatively regulates WNT transcriptional programs in human pluripotent stem cells. Nature Communications. 8: 1034. PMID 29044119 DOI: 10.1038/S41467-017-01203-1 |
0.735 |
|
| 2017 |
Brafman D, Willert K. Wnt/β-catenin signaling during early vertebrate neural development. Developmental Neurobiology. PMID 28799266 DOI: 10.1002/Dneu.22517 |
0.737 |
|
| 2017 |
Rodvold JJ, Chiu KT, Hiramatsu N, Nussbacher JK, Galimberti V, Mahadevan NR, Willert K, Lin JH, Zanetti M. Intercellular transmission of the unfolded protein response promotes survival and drug resistance in cancer cells. Science Signaling. 10. PMID 28588081 DOI: 10.1126/Scisignal.Aah7177 |
0.444 |
|
| 2017 |
Richter J, Traver D, Willert K. The role of Wnt signaling in hematopoietic stem cell development. Critical Reviews in Biochemistry and Molecular Biology. 1-11. PMID 28508727 DOI: 10.1080/10409238.2017.1325828 |
0.604 |
|
| 2017 |
Minegishi K, Hashimoto M, Ajima R, Takaoka K, Shinohara K, Ikawa Y, Nishimura H, McMahon AP, Willert K, Okada Y, Sasaki H, Shi D, Fujimori T, Ohtsuka T, Igarashi Y, et al. A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking. Developmental Cell. 40: 439-452.e4. PMID 28292423 DOI: 10.1016/J.Devcel.2017.02.010 |
0.401 |
|
| 2016 |
Grainger S, Richter J, Palazón RE, Pouget C, Lonquich B, Wirth S, Grassme KS, Herzog W, Swift MR, Weinstein BM, Traver D, Willert K. Wnt9a Is Required for the Aortic Amplification of Nascent Hematopoietic Stem Cells. Cell Reports. 17: 1595-1606. PMID 27806298 DOI: 10.1016/J.Celrep.2016.10.027 |
0.573 |
|
| 2016 |
Wang Z, Li B, Zhou L, Yu S, Su Z, Song J, Sun Q, Sha O, Wang X, Jiang W, Willert K, Wei L, Carson DA, Lu D. Prodigiosin inhibits Wnt/β-catenin signaling and exerts anticancer activity in breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 27799526 DOI: 10.1073/Pnas.1616336113 |
0.379 |
|
| 2016 |
Huggins IJ, Brafman D, Willert K. Methods to Manipulate and Monitor Wnt Signaling in Human Pluripotent Stem Cells. Methods in Molecular Biology (Clifton, N.J.). 1481: 161-81. PMID 27590161 DOI: 10.1007/978-1-4939-6393-5_16 |
0.762 |
|
| 2016 |
Grainger S, Richter J, Willert K, Traver D. WNT9A is required for an aortic amplification of haematopoietic stem cells Experimental Hematology. 44: S76. DOI: 10.1016/J.Exphem.2016.06.146 |
0.472 |
|
| 2015 |
Kumar N, Richter J, Cutts J, Bush KT, Trujillo C, Nigam SK, Gaasterland T, Brafman D, Willert K. Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells. Elife. 4. PMID 26554899 DOI: 10.7554/Elife.08413 |
0.732 |
|
| 2015 |
Aznar N, Midde KK, Dunkel Y, Lopez-Sanchez I, Pavlova Y, Marivin A, Barbazán J, Murray F, Nitsche U, Janssen KP, Willert K, Goel A, Abal M, Garcia-Marcos M, Ghosh P. Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling. Elife. 4. PMID 26126266 DOI: 10.7554/Elife.07091 |
0.423 |
|
| 2015 |
Kumar N, Richter J, Cutts J, Bush KT, Trujillo C, Nigam SK, Gaasterland T, Brafman D, Willert K. Author response: Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells Elife. DOI: 10.7554/Elife.08413.029 |
0.72 |
|
| 2014 |
Ross J, Busch J, Mintz E, Ng D, Stanley A, Brafman D, Sutton VR, Van den Veyver I, Willert K. A rare human syndrome provides genetic evidence that WNT signaling is required for reprogramming of fibroblasts to induced pluripotent stem cells. Cell Reports. 9: 1770-80. PMID 25464842 DOI: 10.1016/J.Celrep.2014.10.049 |
0.726 |
|
| 2014 |
Moya N, Cutts J, Gaasterland T, Willert K, Brafman DA. Endogenous WNT signaling regulates hPSC-derived neural progenitor cell heterogeneity and specifies their regional identity. Stem Cell Reports. 3: 1015-28. PMID 25458891 DOI: 10.1016/J.Stemcr.2014.10.004 |
0.706 |
|
| 2014 |
Fernandez A, Huggins IJ, Perna L, Brafman D, Lu D, Yao S, Gaasterland T, Carson DA, Willert K. The WNT receptor FZD7 is required for maintenance of the pluripotent state in human embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 1409-14. PMID 24474766 DOI: 10.1073/Pnas.1323697111 |
0.76 |
|
| 2013 |
Brafman DA, Moya N, Allen-Soltero S, Fellner T, Robinson M, McMillen ZL, Gaasterland T, Willert K. Analysis of SOX2-expressing cell populations derived from human pluripotent stem cells. Stem Cell Reports. 1: 464-78. PMID 24286033 DOI: 10.1016/J.Stemcr.2013.09.005 |
0.734 |
|
| 2013 |
Bauer M, Bénard J, Gaasterland T, Willert K, Cappellen D. WNT5A encodes two isoforms with distinct functions in cancers. Plos One. 8: e80526. PMID 24260410 DOI: 10.1371/Journal.Pone.0080526 |
0.334 |
|
| 2013 |
Green JL, Bauer M, Yum KW, Li YC, Cox ML, Willert K, Wahl GM. Use of a molecular genetic platform technology to produce human Wnt proteins reveals distinct local and distal signaling abilities. Plos One. 8: e58395. PMID 23516471 DOI: 10.1371/Journal.Pone.0058395 |
0.532 |
|
| 2013 |
Brafman DA, Phung C, Kumar N, Willert K. Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions. Cell Death and Differentiation. 20: 369-81. PMID 23154389 DOI: 10.1038/Cdd.2012.138 |
0.763 |
|
| 2012 |
Willert K, Nusse R. Wnt proteins. Cold Spring Harbor Perspectives in Biology. 4: a007864. PMID 22952392 DOI: 10.1101/cshperspect.a007864 |
0.344 |
|
| 2012 |
Brafman DA, Chien S, Willert K. Arrayed cellular microenvironments for identifying culture and differentiation conditions for stem, primary and rare cell populations. Nature Protocols. 7: 703-17. PMID 22422316 DOI: 10.1038/Nprot.2012.017 |
0.74 |
|
| 2012 |
Gallegos TF, Kouznetsova V, Kudlicka K, Sweeney DE, Bush KT, Willert K, Farquhar MG, Nigam SK. A protein kinase A and Wnt-dependent network regulating an intermediate stage in epithelial tubulogenesis during kidney development. Developmental Biology. 364: 11-21. PMID 22290330 DOI: 10.1016/J.Ydbio.2012.01.014 |
0.473 |
|
| 2012 |
Bauer M, Willert K. Wnt signaling: the β-cat(enin)'s meow. Genes & Development. 26: 105-9. PMID 22279043 DOI: 10.1101/Gad.185280.111 |
0.416 |
|
| 2012 |
Mulligan KA, Fuerer C, Ching W, Fish M, Willert K, Nusse R. Secreted Wingless-interacting molecule (Swim) promotes long-range signaling by maintaining Wingless solubility. Proceedings of the National Academy of Sciences of the United States of America. 109: 370-7. PMID 22203956 DOI: 10.1073/Pnas.1119197109 |
0.425 |
|
| 2010 |
Brafman DA, Chang CW, Fernandez A, Willert K, Varghese S, Chien S. Long-term human pluripotent stem cell self-renewal on synthetic polymer surfaces. Biomaterials. 31: 9135-44. PMID 20817292 DOI: 10.1016/J.Biomaterials.2010.08.007 |
0.691 |
|
| 2010 |
Hu T, Li C, Cao Z, Van Raay TJ, Smith JG, Willert K, Solnica-Krezel L, Coffey RJ. Myristoylated Naked2 antagonizes Wnt-beta-catenin activity by degrading Dishevelled-1 at the plasma membrane. The Journal of Biological Chemistry. 285: 13561-8. PMID 20177058 DOI: 10.1074/Jbc.M109.075945 |
0.375 |
|
| 2009 |
Brafman DA, de Minicis S, Seki E, Shah KD, Teng D, Brenner D, Willert K, Chien S. Investigating the role of the extracellular environment in modulating hepatic stellate cell biology with arrayed combinatorial microenvironments. Integrative Biology : Quantitative Biosciences From Nano to Macro. 1: 513-24. PMID 20023766 DOI: 10.1039/B912926J |
0.694 |
|
| 2009 |
Lu D, Liu JX, Endo T, Zhou H, Yao S, Willert K, Schmidt-Wolf IG, Kipps TJ, Carson DA. Ethacrynic acid exhibits selective toxicity to chronic lymphocytic leukemia cells by inhibition of the Wnt/beta-catenin pathway. Plos One. 4: e8294. PMID 20011538 DOI: 10.1371/Journal.Pone.0008294 |
0.449 |
|
| 2009 |
Lancaster MA, Louie CM, Silhavy JL, Sintasath L, Decambre M, Nigam SK, Willert K, Gleeson JG. Impaired Wnt-beta-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathy. Nature Medicine. 15: 1046-54. PMID 19718039 DOI: 10.1038/Nm.2010 |
0.315 |
|
| 2009 |
Eguchi A, Meade BR, Chang YC, Fredrickson CT, Willert K, Puri N, Dowdy SF. Efficient siRNA delivery into primary cells by a peptide transduction domain-dsRNA binding domain fusion protein. Nature Biotechnology. 27: 567-71. PMID 19448630 DOI: 10.1038/Nbt.1541 |
0.388 |
|
| 2009 |
Brafman DA, Shah KD, Fellner T, Chien S, Willert K. Defining long-term maintenance conditions of human embryonic stem cells with arrayed cellular microenvironment technology. Stem Cells and Development. 18: 1141-54. PMID 19327010 DOI: 10.1089/Scd.2008.0410 |
0.727 |
|
| 2008 |
Soda M, Willert K, Kaushansky K, Geddis AE. Inhibition of GSK-3beta promotes survival and proliferation of megakaryocytic cells through a beta-catenin-independent pathway. Cellular Signalling. 20: 2317-23. PMID 18804163 DOI: 10.1016/J.Cellsig.2008.09.001 |
0.357 |
|
| 2008 |
De Minicis S, Brafman D, Marzioni M, Seki E, Willert K, Chien S, Benedetti A, Brenner DA. Extracellular matrix combinations differentially modulate hepatic stellate cell biology Digestive and Liver Disease. 40: A132-A133. DOI: 10.1016/J.Dld.2008.07.164 |
0.665 |
|
| 2006 |
Willert K, Jones KA. Wnt signaling: is the party in the nucleus? Genes & Development. 20: 1394-404. PMID 16751178 DOI: 10.1101/Gad.1424006 |
0.396 |
|
| 2006 |
Galli LM, Barnes T, Cheng T, Acosta L, Anglade A, Willert K, Nusse R, Burrus LW. Differential inhibition of Wnt-3a by Sfrp-1, Sfrp-2, and Sfrp-3. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 235: 681-90. PMID 16425220 DOI: 10.1002/Dvdy.20681 |
0.428 |
|
| 2006 |
Minami Y, Stuart S, Ikawa T, Banno A, Hunton I, Willert K, Murre C, Jamieson C, Wang JY. Imatinib-Resistant Activation of β-Catenin by BCR-ABL in a Murine Model of Chronic Myelogenous Leukemia Stem Cells. Blood. 108: 2126-2126. DOI: 10.1182/Blood.V108.11.2126.2126 |
0.47 |
|
| 2005 |
Duncan AW, Rattis FM, DiMascio LN, Congdon KL, Pazianos G, Zhao C, Yoon K, Cook JM, Willert K, Gaiano N, Reya T. Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance. Nature Immunology. 6: 314-22. PMID 15665828 DOI: 10.1038/Ni1164 |
0.596 |
|
| 2005 |
DiMascio L, Congdon K, Pazianos G, Zhao C, Cook JM, Willert K. Notch as a target to modulate hematopoietic stem cell differentiation Cancer Biology and Therapy. 4. |
0.422 |
|
| 2004 |
Galli LM, Willert K, Nusse R, Yablonka-Reuveni Z, Nohno T, Denetclaw W, Burrus LW. A proliferative role for Wnt-3a in chick somites. Developmental Biology. 269: 489-504. PMID 15110715 DOI: 10.1016/J.Ydbio.2004.01.041 |
0.375 |
|
| 2003 |
Willert K, Brown JD, Danenberg E, Duncan AW, Weissman IL, Reya T, Yates JR, Nusse R. Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature. 423: 448-52. PMID 12717451 DOI: 10.1038/Nature01611 |
0.525 |
|
| 2003 |
Reya T, Duncan AW, Ailles L, Domen J, Scherer DC, Willert K, Hintz L, Nusse R, Weissman IL. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature. 423: 409-14. PMID 12717450 DOI: 10.1038/Nature01593 |
0.574 |
|
| 2001 |
Wilson SI, Rydström A, Trimborn T, Willert K, Nusse R, Jessell TM, Edlund T. The status of Wnt signalling regulates neural and epidermal fates in the chick embryo. Nature. 411: 325-30. PMID 11357137 DOI: 10.1038/35077115 |
0.509 |
|
| 2000 |
Reya T, O'Riordan M, Okamura R, Devaney E, Willert K, Nusse R, Grosschedl R. Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism. Immunity. 13: 15-24. PMID 10933391 DOI: 10.1016/S1074-7613(00)00004-2 |
0.433 |
|
| 1999 |
Willert K, Logan CY, Arora A, Fish M, Nusse R. A Drosophila Axin homolog, Daxin, inhibits Wnt signaling. Development (Cambridge, England). 126: 4165-73. PMID 10457025 |
0.333 |
|
| 1999 |
Willert K, Shibamoto S, Nusse R. Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex. Genes & Development. 13: 1768-73. PMID 10421629 DOI: 10.1101/Gad.13.14.1768 |
0.352 |
|
| 1999 |
Millar SE, Willert K, Salinas PC, Roelink H, Nusse R, Sussman DJ, Barsh GS. WNT signaling in the control of hair growth and structure. Developmental Biology. 207: 133-49. PMID 10049570 DOI: 10.1006/Dbio.1998.9140 |
0.509 |
|
| 1998 |
Willert K, Nusse R. Beta-catenin: a key mediator of Wnt signaling. Current Opinion in Genetics & Development. 8: 95-102. PMID 9529612 DOI: 10.1016/S0959-437X(98)80068-3 |
0.363 |
|
| 1998 |
Korinek V, Barker N, Willert K, Molenaar M, Roose J, Wagenaar G, Markman M, Lamers W, Destree O, Clevers H. Two members of the Tcf family implicated in Wnt/β-catenin signaling during embryogenesis in the mouse Molecular and Cellular Biology. 18: 1248-1256. PMID 9488439 DOI: 10.1128/Mcb.18.3.1248 |
0.405 |
|
| 1997 |
Nusse R, Samos CH, Brink M, Willert K, Cadigan KM, Wodarz A, Fish M, Rulifson E. Cell culture and whole animal approaches to understanding signaling by Wnt proteins in Drosophila. Cold Spring Harbor Symposia On Quantitative Biology. 62: 185-90. PMID 9598351 DOI: 10.1101/Sqb.1997.062.01.024 |
0.473 |
|
| 1993 |
Shackleford GM, Willert K, Wang J, Varmus HE. The Wnt-1 proto-oncogene induces changes in morphology, gene expression, and growth factor responsiveness in PC12 cells. Neuron. 11: 865-75. PMID 8240810 DOI: 10.1016/0896-6273(93)90116-9 |
0.46 |
|
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