Karl Willert - Publications

Affiliations: 
Bioengineering University of California, San Diego, La Jolla, CA 
Area:
Biomedical

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Huggins IJ, Bos T, Gaylord O, Jessen C, Lonquich B, Puranen A, Richter J, Rossdam C, Brafman D, Gaasterland T, Willert K. The WNT target SP5 negatively regulates WNT transcriptional programs in human pluripotent stem cells. Nature Communications. 8: 1034. PMID 29044119 DOI: 10.1038/s41467-017-01203-1  0.44
2015 Kumar N, Richter J, Cutts J, Bush KT, Trujillo C, Nigam SK, Gaasterland T, Brafman D, Willert K. Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells. Elife. 4. PMID 26554899 DOI: 10.7554/eLife.08413  0.56
2015 Aznar N, Midde KK, Dunkel Y, Lopez-Sanchez I, Pavlova Y, Marivin A, Barbazán J, Murray F, Nitsche U, Janssen KP, Willert K, Goel A, Abal M, Garcia-Marcos M, Ghosh P. Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling. Elife. 4. PMID 26126266 DOI: 10.7554/eLife.07091  0.56
2014 Ross J, Busch J, Mintz E, Ng D, Stanley A, Brafman D, Sutton VR, Van den Veyver I, Willert K. A rare human syndrome provides genetic evidence that WNT signaling is required for reprogramming of fibroblasts to induced pluripotent stem cells. Cell Reports. 9: 1770-80. PMID 25464842 DOI: 10.1016/j.celrep.2014.10.049  0.56
2014 Moya N, Cutts J, Gaasterland T, Willert K, Brafman DA. Endogenous WNT signaling regulates hPSC-derived neural progenitor cell heterogeneity and specifies their regional identity. Stem Cell Reports. 3: 1015-28. PMID 25458891 DOI: 10.1016/j.stemcr.2014.10.004  0.56
2014 Fernandez A, Huggins IJ, Perna L, Brafman D, Lu D, Yao S, Gaasterland T, Carson DA, Willert K. The WNT receptor FZD7 is required for maintenance of the pluripotent state in human embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 1409-14. PMID 24474766 DOI: 10.1073/pnas.1323697111  0.56
2013 Brafman DA, Moya N, Allen-Soltero S, Fellner T, Robinson M, McMillen ZL, Gaasterland T, Willert K. Analysis of SOX2-expressing cell populations derived from human pluripotent stem cells. Stem Cell Reports. 1: 464-78. PMID 24286033 DOI: 10.1016/j.stemcr.2013.09.005  0.56
2013 Bauer M, Bénard J, Gaasterland T, Willert K, Cappellen D. WNT5A encodes two isoforms with distinct functions in cancers. Plos One. 8: e80526. PMID 24260410 DOI: 10.1371/journal.pone.0080526  0.56
2013 Green JL, Bauer M, Yum KW, Li YC, Cox ML, Willert K, Wahl GM. Use of a molecular genetic platform technology to produce human Wnt proteins reveals distinct local and distal signaling abilities. Plos One. 8: e58395. PMID 23516471 DOI: 10.1371/journal.pone.0058395  0.56
2013 Brafman DA, Phung C, Kumar N, Willert K. Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions. Cell Death and Differentiation. 20: 369-81. PMID 23154389 DOI: 10.1038/cdd.2012.138  0.56
2012 Willert K, Nusse R. Wnt proteins. Cold Spring Harbor Perspectives in Biology. 4: a007864. PMID 22952392 DOI: 10.1101/cshperspect.a007864  0.56
2012 Brafman DA, Chien S, Willert K. Arrayed cellular microenvironments for identifying culture and differentiation conditions for stem, primary and rare cell populations. Nature Protocols. 7: 703-17. PMID 22422316 DOI: 10.1038/nprot.2012.017  0.56
2012 Gallegos TF, Kouznetsova V, Kudlicka K, Sweeney DE, Bush KT, Willert K, Farquhar MG, Nigam SK. A protein kinase A and Wnt-dependent network regulating an intermediate stage in epithelial tubulogenesis during kidney development. Developmental Biology. 364: 11-21. PMID 22290330 DOI: 10.1016/j.ydbio.2012.01.014  0.56
2012 Bauer M, Willert K. Wnt signaling: the β-cat(enin)'s meow. Genes & Development. 26: 105-9. PMID 22279043 DOI: 10.1101/gad.185280.111  0.56
2012 Mulligan KA, Fuerer C, Ching W, Fish M, Willert K, Nusse R. Secreted Wingless-interacting molecule (Swim) promotes long-range signaling by maintaining Wingless solubility. Proceedings of the National Academy of Sciences of the United States of America. 109: 370-7. PMID 22203956 DOI: 10.1073/pnas.1119197109  0.56
2010 Brafman DA, Chang CW, Fernandez A, Willert K, Varghese S, Chien S. Long-term human pluripotent stem cell self-renewal on synthetic polymer surfaces. Biomaterials. 31: 9135-44. PMID 20817292 DOI: 10.1016/j.biomaterials.2010.08.007  0.56
2010 Hu T, Li C, Cao Z, Van Raay TJ, Smith JG, Willert K, Solnica-Krezel L, Coffey RJ. Myristoylated Naked2 antagonizes Wnt-beta-catenin activity by degrading Dishevelled-1 at the plasma membrane. The Journal of Biological Chemistry. 285: 13561-8. PMID 20177058 DOI: 10.1074/jbc.M109.075945  0.56
2009 Brafman DA, de Minicis S, Seki E, Shah KD, Teng D, Brenner D, Willert K, Chien S. Investigating the role of the extracellular environment in modulating hepatic stellate cell biology with arrayed combinatorial microenvironments. Integrative Biology : Quantitative Biosciences From Nano to Macro. 1: 513-24. PMID 20023766 DOI: 10.1039/b912926j  0.56
2009 Lu D, Liu JX, Endo T, Zhou H, Yao S, Willert K, Schmidt-Wolf IG, Kipps TJ, Carson DA. Ethacrynic acid exhibits selective toxicity to chronic lymphocytic leukemia cells by inhibition of the Wnt/beta-catenin pathway. Plos One. 4: e8294. PMID 20011538 DOI: 10.1371/journal.pone.0008294  0.56
2009 Lancaster MA, Louie CM, Silhavy JL, Sintasath L, Decambre M, Nigam SK, Willert K, Gleeson JG. Impaired Wnt-beta-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathy. Nature Medicine. 15: 1046-54. PMID 19718039 DOI: 10.1038/nm.2010  0.56
2009 Eguchi A, Meade BR, Chang YC, Fredrickson CT, Willert K, Puri N, Dowdy SF. Efficient siRNA delivery into primary cells by a peptide transduction domain-dsRNA binding domain fusion protein. Nature Biotechnology. 27: 567-71. PMID 19448630 DOI: 10.1038/nbt.1541  0.56
2009 Brafman DA, Shah KD, Fellner T, Chien S, Willert K. Defining long-term maintenance conditions of human embryonic stem cells with arrayed cellular microenvironment technology. Stem Cells and Development. 18: 1141-54. PMID 19327010 DOI: 10.1089/scd.2008.0410  0.56
2008 Willert KH. Isolation and application of bioactive Wnt proteins. Methods in Molecular Biology (Clifton, N.J.). 468: 17-29. PMID 19099243 DOI: 10.1007/978-1-59745-249-6_2  0.56
2008 Soda M, Willert K, Kaushansky K, Geddis AE. Inhibition of GSK-3beta promotes survival and proliferation of megakaryocytic cells through a beta-catenin-independent pathway. Cellular Signalling. 20: 2317-23. PMID 18804163 DOI: 10.1016/j.cellsig.2008.09.001  0.56
2006 Willert K, Jones KA. Wnt signaling: is the party in the nucleus? Genes & Development. 20: 1394-404. PMID 16751178 DOI: 10.1101/gad.1424006  0.56
2006 Galli LM, Barnes T, Cheng T, Acosta L, Anglade A, Willert K, Nusse R, Burrus LW. Differential inhibition of Wnt-3a by Sfrp-1, Sfrp-2, and Sfrp-3. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 235: 681-90. PMID 16425220 DOI: 10.1002/dvdy.20681  0.56
2005 Duncan AW, Rattis FM, DiMascio LN, Congdon KL, Pazianos G, Zhao C, Yoon K, Cook JM, Willert K, Gaiano N, Reya T. Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance. Nature Immunology. 6: 314-22. PMID 15665828 DOI: 10.1038/ni1164  0.56
2005 DiMascio L, Congdon K, Pazianos G, Zhao C, Cook JM, Willert K. Notch as a target to modulate hematopoietic stem cell differentiation Cancer Biology and Therapy. 4.  0.56
2004 Galli LM, Willert K, Nusse R, Yablonka-Reuveni Z, Nohno T, Denetclaw W, Burrus LW. A proliferative role for Wnt-3a in chick somites. Developmental Biology. 269: 489-504. PMID 15110715 DOI: 10.1016/j.ydbio.2004.01.041  0.56
2003 Willert K, Brown JD, Danenberg E, Duncan AW, Weissman IL, Reya T, Yates JR, Nusse R. Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature. 423: 448-52. PMID 12717451 DOI: 10.1038/nature01611  0.56
2003 Reya T, Duncan AW, Ailles L, Domen J, Scherer DC, Willert K, Hintz L, Nusse R, Weissman IL. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature. 423: 409-14. PMID 12717450 DOI: 10.1038/nature01593  0.56
2001 Wilson SI, Rydström A, Trimborn T, Willert K, Nusse R, Jessell TM, Edlund T. The status of Wnt signalling regulates neural and epidermal fates in the chick embryo. Nature. 411: 325-30. PMID 11357137 DOI: 10.1038/35077115  0.56
2000 Reya T, O'Riordan M, Okamura R, Devaney E, Willert K, Nusse R, Grosschedl R. Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism. Immunity. 13: 15-24. PMID 10933391  0.56
1999 Willert K, Logan CY, Arora A, Fish M, Nusse R. A Drosophila Axin homolog, Daxin, inhibits Wnt signaling. Development (Cambridge, England). 126: 4165-73. PMID 10457025  0.56
1999 Willert K, Shibamoto S, Nusse R. Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex. Genes & Development. 13: 1768-73. PMID 10421629  0.56
1999 Millar SE, Willert K, Salinas PC, Roelink H, Nusse R, Sussman DJ, Barsh GS. WNT signaling in the control of hair growth and structure. Developmental Biology. 207: 133-49. PMID 10049570 DOI: 10.1006/dbio.1998.9140  0.56
1998 Willert K, Nusse R. Beta-catenin: a key mediator of Wnt signaling. Current Opinion in Genetics & Development. 8: 95-102. PMID 9529612 DOI: 10.1016/S0959-437X(98)80068-3  0.56
1998 Korinek V, Barker N, Willert K, Molenaar M, Roose J, Wagenaar G, Markman M, Lamers W, Destree O, Clevers H. Two members of the Tcf family implicated in Wnt/β-catenin signaling during embryogenesis in the mouse Molecular and Cellular Biology. 18: 1248-1256. PMID 9488439  0.56
1997 Nusse R, Samos CH, Brink M, Willert K, Cadigan KM, Wodarz A, Fish M, Rulifson E. Cell culture and whole animal approaches to understanding signaling by Wnt proteins in Drosophila. Cold Spring Harbor Symposia On Quantitative Biology. 62: 185-90. PMID 9598351  0.56
1997 Willert K, Brink M, Wodarz A, Varmus H, Nusse R. Casein kinase 2 associates with and phosphorylates dishevelled Embo Journal. 16: 3089-3096. PMID 9214626 DOI: 10.1093/emboj/16.11.3089  0.56
1993 Shackleford GM, Willert K, Wang J, Varmus HE. The Wnt-1 proto-oncogene induces changes in morphology, gene expression, and growth factor responsiveness in PC12 cells. Neuron. 11: 865-75. PMID 8240810 DOI: 10.1016/0896-6273(93)90116-9  0.56
1990 Young JA, Bates P, Willert K, Varmus HE. Efficient incorporation of human CD4 protein into avian leukosis virus particles. Science (New York, N.Y.). 250: 1421-3. PMID 2175047  0.56
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