Christopher D. Porada - Publications

Affiliations: 
Cell and Molecular Biology University of Nevada, Reno, Reno, NV, United States 
Area:
Molecular Biology, Genetics

137 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Maxwell JT, Almeida-Porada G, Porada CD. Trial offers hope to children with hypoplastic left heart syndrome. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 38382527 DOI: 10.1016/j.ymthe.2024.02.015  0.432
2024 Kuczynski CE, Porada CD, Atala A, Cho SS, Almeida-Porada G. Evaluating sheep hemoglobins with MD simulations as an animal model for sickle cell disease. Scientific Reports. 14: 276. PMID 38168584 DOI: 10.1038/s41598-023-50707-y  0.738
2023 Rodriguez M, Trevisan B, Ramamurthy RM, George SK, Diaz J, Alexander J, Meares D, Schwahn DJ, Quilici DR, Figueroa J, Gautreaux M, Farland A, Atala A, Doering CB, Spencer HT, ... Porada CD, et al. Transplanting FVIII/ET3-secreting cells in fetal sheep increases FVIII levels long-term without inducing immunity or toxicity. Nature Communications. 14: 4206. PMID 37452013 DOI: 10.1038/s41467-023-39986-1  0.582
2023 Pham QDM, Thomson SM, Schaible BN, Mills KD, Atala A, Porada CD, Almeida-Porada G. Acceptability of prenatal diagnosis and prenatal treatment of haemophilia using cell and gene therapies within US haemophilia community. Haemophilia : the Official Journal of the World Federation of Hemophilia. PMID 37228173 DOI: 10.1111/hae.14805  0.518
2022 Ramamurthy RM, Rodriguez M, Ainsworth HC, Shields J, Meares D, Bishop C, Farland A, Langefeld CD, Atala A, Doering CB, Spencer HT, Porada CD, Almeida-Porada G. Comparison of different gene addition strategies to modify placental derived-mesenchymal stromal cells to produce FVIII. Frontiers in Immunology. 13: 954984. PMID 36591257 DOI: 10.3389/fimmu.2022.954984  0.589
2022 Trevisan B, Rodriguez M, Medder H, Lankford S, Combs R, Owen J, Atala A, Porada CD, Almeida-Porada G. Autologous bone marrow-derived MSCs engineered to express oFVIII-FLAG engraft in adult sheep and produce an effective increase in plasma FVIII levels. Frontiers in Immunology. 13: 1070476. PMID 36532079 DOI: 10.3389/fimmu.2022.1070476  0.524
2022 Evans AC, Martin KA, Saxena M, Bicher S, Wheeler E, Cordova EJ, Porada CD, Almeida-Porada G, Kato TA, Wilson PF, Coleman MA. Curcumin Nanodiscs Improve Solubility and Serve as Radiological Protectants against Ionizing Radiation Exposures in a Cell-Cycle Dependent Manner. Nanomaterials (Basel, Switzerland). 12. PMID 36296810 DOI: 10.3390/nano12203619  0.533
2022 Herzeg A, Almeida-Porada G, Charo RA, David AL, Gonzalez-Velez J, Gupta N, Lapteva L, Lianoglou B, Peranteau W, Porada C, Sanders SJ, Sparks TN, Stitelman DH, Struble E, Sumner CJ, et al. Prenatal Somatic Cell Gene Therapies: Charting a Path Toward Clinical Applications (Proceedings of the CERSI-FDA Meeting). Journal of Clinical Pharmacology. S36-S52. PMID 36106778 DOI: 10.1002/jcph.2127  0.54
2021 Stem C, Rodman C, Ramamurthy RM, George S, Meares D, Farland A, Atala A, Doering CB, Spencer HT, Porada CD, Almeida-Porada G. Investigating Optimal Autologous Cellular Platforms for Prenatal or Perinatal Factor VIII Delivery to Treat Hemophilia A. Frontiers in Cell and Developmental Biology. 9: 678117. PMID 34447745 DOI: 10.3389/fcell.2021.678117  0.58
2021 Trevisan B, Morsi A, Aleman J, Rodriguez M, Shields J, Meares D, Farland AM, Doering CB, Spencer HT, Atala A, Skardal A, Porada CD, Almeida-Porada G. Effects of Shear Stress on Production of FVIII and vWF in a Cell-Based Therapeutic for Hemophilia A. Frontiers in Bioengineering and Biotechnology. 9: 639070. PMID 33732691 DOI: 10.3389/fbioe.2021.639070  0.535
2020 Sagar R, Almeida-Porada G, Blakemore K, Chan JK, Choolani M, Götherström C, Jaulent A, MacKenzie TC, Mattar C, Porada CD, Peranteau WH, Schneider H, Shaw SW, Waddington SN, Westgren M, et al. Fetal and maternal safety considerations for in utero therapy clinical trials: iFeTiS consensus statement. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 33069884 DOI: 10.1016/j.ymthe.2020.10.012  0.483
2020 Trevisan BM, Porada CD, Atala A, Almeida-Porada G. Microfluidic devices for studying coagulation biology. Seminars in Cell & Developmental Biology. PMID 32563678 DOI: 10.1016/J.Semcdb.2020.06.002  0.563
2020 El-Akabawy N, Rodriguez M, Ramamurthy R, Rabah A, Trevisan B, Morsi A, George S, Shields J, Meares D, Farland A, Atala A, Doering CB, Spencer HT, Porada CD, Almeida-Porada G. Defining the Optimal FVIII Transgene for Placental Cell-Based Gene Therapy to Treat Hemophilia A. Molecular Therapy. Methods & Clinical Development. 17: 465-477. PMID 32258210 DOI: 10.1016/J.Omtm.2020.03.001  0.635
2020 Almeida-Porada G, Atala AJ, Porada CD. Therapeutic Mesenchymal Stromal Cells for Immunotherapy and for Gene and Drug Delivery. Molecular Therapy. Methods & Clinical Development. 16: 204-224. PMID 32071924 DOI: 10.1016/J.Omtm.2020.01.005  0.619
2020 Markusic DM, Martino AT, Porada CD, VandenDriessche T. Immunology of Gene and Cell Therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 32023479 DOI: 10.1016/J.Ymthe.2020.01.024  0.367
2020 Chiloff DM, de Almeida DC, Dalboni MA, Canziani MEF, George SK, Morsi AM, El-Akabawy N, Porada CD, Durao MS, Zarjou A, Almeida-Porada G, Goes MA. Soluble Fas affects erythropoiesis and acts as potential predictor of erythropoiesis-stimulating agents therapy in chronic kidney disease patients. American Journal of Physiology. Renal Physiology. PMID 32003597 DOI: 10.1152/Ajprenal.00433.2019  0.558
2020 Pham QD, Rodriguez M, Ramamurthy RM, George S, Figueroa J, Atala A, Doering CB, Spencer HT, Porada CD, Almeida-Porada MG. Evaluation of Maternal Safety Following Prenatal Cell and Gene Therapy for Hemophilia a in a Large Animal Model Demonstrates Absence of Maternal Exposure to the Cells or Gene Products Infused into the Fetus Blood. 136: 32-32. DOI: 10.1182/blood-2020-140883  0.364
2020 Rodriguez M, Trevisan B, George S, Ramamurthy RM, Rabah A, Shields JE, Schwahn D, Figueroa J, Meares D, Owen J, Gautreaux M, Atala A, Doering CB, Spencer HT, Porada CD, et al. Administration of Cells Engineered to Secrete Fviii-mcoET3 in Prenatal Sheep Recipients Results in Sustained Curative Fviii Plasma Levels for 3 Years after Birth, without Immune or Toxicity-Related Adverse Events Blood. 136: 1-2. DOI: 10.1182/blood-2020-140845  0.358
2020 Trevisan B, Rodriguez M, George S, Lankford S, Shields JE, Figueroa J, Meares D, Owen J, Atala A, Doering CB, Spencer HT, Porada CD, Almeida-Porada MG. Delivery of Fviii-mcoET3 to Previously Untreated Sheep Using Human Placental Cells Enables Durable Elevation of Plasma FVIII Levels and Avoids Inhibitor Formation Blood. 136: 34-34. DOI: 10.1182/BLOOD-2020-140745  0.303
2019 Rodriguez M, Porada CD, Almeida-Porada G. Mechanistic Insights into Factor VIII Immune Tolerance Induction via Prenatal Cell Therapy in Hemophilia A. Current Stem Cell Reports. 5: 145-161. PMID 32351874 DOI: 10.1007/S40778-019-00165-Y  0.638
2019 Aleman J, George SK, Herberg S, Devarasetty M, Porada CD, Skardal A, Almeida-Porada G. Deconstructed Microfluidic Bone Marrow On-A-Chip to Study Normal and Malignant Hemopoietic Cell-Niche Interactions. Small (Weinheim An Der Bergstrasse, Germany). e1902971. PMID 31464364 DOI: 10.1002/Smll.201902971  0.645
2019 Almeida-Porada G, Waddington SN, Chan JKY, Peranteau WH, MacKenzie T, Porada CD. In Utero Gene Therapy Consensus Statement from the IFeTIS. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30837116 DOI: 10.1016/J.Ymthe.2019.02.015  0.544
2019 Valdes RC, Hernandez AJ, Nikiforov MA, Almeida-Porada G, Porada C, George S, Maycock A, Skardal A. PATIENT-SPECIFIC MULTIPLE MYELOMA MODEL USING 3D PRINTED ORGANOIDS FOR PREDICTING AND UNDERSTANDING TREATMENT RESPONSE Hemasphere. 3: 945-946. DOI: 10.1097/01.HS9.0000566880.76874.BE  0.471
2019 Ascensão J, Porada C, Almeida-Porada G, McGlave P, Hoffman R. In Memoriam: A Tribute to Esmail Zanjani, 1938–2019 Experimental Hematology. 79: 1-2. DOI: 10.1016/J.Exphem.2019.11.005  0.425
2019 Rodriguez C, Aleman J, Almeida-Porada G, Porada C, Nikiforov M, Skardal A. High throughput 3D bioprinting of patient-derived multiple myeloma organoid models for niche recapitulation and chemosensitivity assessment. Clinical Lymphoma Myeloma and Leukemia. 19: e30-e31. DOI: 10.1016/J.Clml.2019.09.045  0.537
2019 Rodriguez C, Aleman J, George S, Maycock A, Nikiforov M, Porada C, Almeida-Porada G, Skardal A. Patient-Specific 3D Printed Multiple Myeloma Organoid Model for Niche Recapitulation and Prediction of Chemotherapy Response Clinical Lymphoma Myeloma and Leukemia. 19: S336. DOI: 10.1016/J.Clml.2019.07.332  0.526
2018 Low EK, Brudvik E, Kuhlman BM, Wilson PF, Almeida-Porada GM, Porada CD. Microgravity Impairs DNA Damage Repair in Human Hematopoietic stem/progenitor cells and Inhibits Their Differentiation into Dendritic Cells. Stem Cells and Development. PMID 29901426 DOI: 10.1089/Scd.2018.0052  0.628
2018 Mokhtari S, Colletti E, Yin W, Sanada C, Lamar Z, Simmons PJ, Walker S, Bishop C, Atala A, Zanjani ED, Porada CD, Almeida-Porada G. Correction: A human bone marrow mesodermal-derived cell population with hemogenic potential. Leukemia. PMID 29891936 DOI: 10.1038/S41375-018-0172-3  0.58
2018 Almeida-Porada G, Rodman C, Kuhlman B, Brudvik E, Moon J, George S, Guida P, Sajuthi SP, Langefeld CD, Walker SJ, Wilson PF, Porada CD. Exposure of the Bone Marrow Microenvironment to Simulated Solar and Galactic Cosmic Radiation Induces Biological Bystander Effects on Human Hematopoiesis. Stem Cells and Development. PMID 29698131 DOI: 10.1089/scd.2018.0005  0.61
2018 Mokhtari S, Baptista PM, Vyas DA, Freeman CJ, Moran E, Brovold M, Llamazares GA, Lamar Z, Porada CD, Soker S, Almeida-Porada G. Evaluating Interaction of Cord Blood Hematopoietic Stem/Progenitor Cells with Functionally Integrated Three-Dimensional Microenvironments. Stem Cells Translational Medicine. PMID 29473346 DOI: 10.1002/Sctm.17-0157  0.644
2018 Mokhtari S, Colletti E, Yin W, Sanada C, Lamar Z, Simmons PJ, Walker S, Bishop C, Atala A, Zanjani ED, Porada CD, Almeida-Porada G. A human bone marrow mesodermal-derived cell population with hemogenic potential. Leukemia. PMID 29467489 DOI: 10.1038/S41375-018-0016-1  0.676
2017 Almeida-Porada MG, George S, Morsi A, El-Akabawy N, Figueroa J, Shields JE, Meares D, Farland AM, Atala A, Doering CB, Spencer HT, Porada CD. Prenatal Transplantation of Placental Cells Engineered to Express FVIII Leads to Corrective Plasma Levels of FVIII after Birth Blood. 130: 361-361. DOI: 10.1182/Blood.V130.Suppl_1.361.361  0.48
2016 Rodman C, Almeida-Porada G, George S, Moon J, Soker S, Pardee T, Beaty M, Guida P, Sajuthi SP, Langefeld CD, Walker SJ, Wilson PF, Porada CD. In vitro and in vivo assessment of direct effects of simulated solar and galactic cosmic radiation on human hematopoietic stem/progenitor cells. Leukemia. PMID 27881872 DOI: 10.1038/Leu.2016.344  0.585
2016 Mokhtari S, Colletti EJ, Atala A, Zanjani ED, Porada CD, Almeida-Porada G. Boosting Hematopoietic Engraftment after in Utero Transplantation through Vascular Niche Manipulation. Stem Cell Reports. 6: 957-69. PMID 27304918 DOI: 10.1016/J.Stemcr.2016.05.009  0.678
2016 Almeida-Porada G, Atala A, Porada CD. In utero stem cell transplantation and gene therapy: rationale, history, and recent advances toward clinical application. Molecular Therapy. Methods & Clinical Development. 5: 16020. PMID 27069953 DOI: 10.1038/Mtm.2016.20  0.65
2015 Muralidharan S, Sasi SP, Zuriaga MA, Hirschi KK, Porada CD, Coleman MA, Walsh KX, Yan X, Goukassian DA. Ionizing Particle Radiation as a Modulator of Endogenous Bone Marrow Cell Reprogramming: Implications for Hematological Cancers. Frontiers in Oncology. 5: 231. PMID 26528440 DOI: 10.3389/Fonc.2015.00231  0.409
2015 Porada CD, Atala AJ, Almeida-Porada G. The hematopoietic system in the context of regenerative medicine. Methods (San Diego, Calif.). PMID 26319943 DOI: 10.1016/J.Ymeth.2015.08.015  0.649
2015 Ross CL, Siriwardane M, Almeida-Porada G, Porada CD, Brink P, Christ GJ, Harrison BS. The effect of low-frequency electromagnetic field on human bone marrow stem/progenitor cell differentiation. Stem Cell Research. 15: 96-108. PMID 26042793 DOI: 10.1016/J.Scr.2015.04.009  0.637
2015 Shaw SW, Blundell MP, Pipino C, Shangaris P, Maghsoudlou P, Ramachandra DL, Georgiades F, Boyd M, Thrasher AJ, Porada CD, Almeida-Porada G, Cheng PJ, David AL, de Coppi P. Sheep CD34+ amniotic fluid cells have hematopoietic potential and engraft after autologous in utero transplantation. Stem Cells (Dayton, Ohio). 33: 122-32. PMID 25186828 DOI: 10.1002/Stem.1839  0.673
2015 Mokhtari S, Baptista P, Vyas D, Freeman CJ, Moran E, Porada CD, Soker S, Almeida-Porada G. A New Approach to Expand Cord Blood Derived Hematopoietic Stem Cells, Using Bioengineered Human Fetal Liver Tissue 3D-Constructs Blood. 126: 3097-3097. DOI: 10.1182/Blood.V126.23.3097.3097  0.622
2015 Mokhtari S, Porada CD, Colletti EJ, Almeida-Porada G. Defining Engraftment Patterns and Interactions Between Hematopoietic Stem Cells and Stromal Cells after in Utero Transplantation Blood. 126: 1869-1869. DOI: 10.1182/Blood.V126.23.1869.1869  0.677
2015 Mokhtari S, Colletti EJ, Sanada C, Lamar ZS, Simmons PJ, Atala A, Krause DS, Zanjani ED, Porada CD, Almeida-Porada G. A Human Bone Marrow-Derived Stromal Cell Population with Hemogenic Potential Blood. 126: 1201-1201. DOI: 10.1182/Blood.V126.23.1201.1201  0.683
2014 Porada CD, Rodman C, Ignacio G, Atala A, Almeida-Porada G. Hemophilia A: an ideal disease to correct in utero. Frontiers in Pharmacology. 5: 276. PMID 25566073 DOI: 10.3389/Fphar.2014.00276  0.61
2014 Boura JS, Vance M, Yin W, Madeira C, Lobato da Silva C, Porada CD, Almeida-Porada G. Evaluation of gene delivery strategies to efficiently overexpress functional HLA-G on human bone marrow stromal cells. Molecular Therapy. Methods & Clinical Development. 2014. PMID 25279386 DOI: 10.1038/Mtm.2014.41  0.603
2014 Jeanblanc C, Goodrich AD, Colletti E, Mokhtari S, Porada CD, Zanjani ED, Almeida-Porada G. Temporal definition of haematopoietic stem cell niches in a large animal model of in utero stem cell transplantation. British Journal of Haematology. 166: 268-78. PMID 24673111 DOI: 10.1111/Bjh.12870  0.683
2014 Soland MA, Keyes LR, Bayne R, Moon J, Porada CD, St Jeor S, Almeida-Porada G. Perivascular stromal cells as a potential reservoir of human cytomegalovirus. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 14: 820-30. PMID 24592822 DOI: 10.1111/Ajt.12642  0.644
2014 Almeida-Porada G, Porada CD. Hematopoiesis in Regenerative Medicine Translational Regenerative Medicine. 375-401. DOI: 10.1016/B978-0-12-410396-2.00028-1  0.619
2013 Porada CD, Stem C, Almeida-Porada G. Gene therapy: the promise of a permanent cure. North Carolina Medical Journal. 74: 526-9. PMID 24316783  0.54
2013 Tellez J, Van Vliet K, Tseng YS, Finn JD, Tschernia N, Almeida-Porada G, Arruda VR, Agbandje-McKenna M, Porada CD. Characterization of naturally-occurring humoral immunity to AAV in sheep. Plos One. 8: e75142. PMID 24086458 DOI: 10.1371/Journal.Pone.0075142  0.779
2013 Almeida-Porada G, Soland M, Boura J, Porada CD. Regenerative medicine: prospects for the treatment of inflammatory bowel disease. Regenerative Medicine. 8: 631-44. PMID 23998755 DOI: 10.2217/Rme.13.52  0.594
2013 Soland MA, Bego M, Colletti E, Zanjani ED, St Jeor S, Porada CD, Almeida-Porada G. Mesenchymal stem cells engineered to inhibit complement-mediated damage. Plos One. 8: e60461. PMID 23555976 DOI: 10.1182/Blood.V120.21.1253.1253  0.617
2013 Colletti E, El Shabrawy D, Soland M, Yamagami T, Mokhtari S, Osborne C, Schlauch K, Zanjani ED, Porada CD, Almeida-Porada G. EphB2 isolates a human marrow stromal cell subpopulation with enhanced ability to contribute to the resident intestinal cellular pool. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 2111-21. PMID 23413357 DOI: 10.1096/Fj.12-205054  0.643
2013 Sanada C, Kuo CJ, Colletti EJ, Soland M, Mokhtari S, Knovich MA, Owen J, Zanjani ED, Porada CD, Almeida-Porada G. Mesenchymal stem cells contribute to endogenous FVIII:c production. Journal of Cellular Physiology. 228: 1010-6. PMID 23042590 DOI: 10.1002/Jcp.24247  0.656
2013 Zakas PM, Gangadharan B, Almeida-Porada G, Porada CD, Spencer HT, Doering CB. Expression of Recombinant Ovine and Human fVIII. Plos One. DOI: 10.1371/Journal.Pone.0049481.G001  0.567
2013 Mokhtari S, Colletti E, Porada CD, Almeida-Porada G. Optimization Of Vascular Niches To Increase Hematopoietic Engraftment Blood. 122: 4456-4456. DOI: 10.1182/Blood.V122.21.4456.4456  0.687
2013 Yin W, Porada CD, Walker S, Bishop C. RUNX1C-Mediated Reprogramming Of Human Bone Marrow Stromal Cells into Early Blood Progenitors Blood. 122: 2463-2463. DOI: 10.1182/Blood.V122.21.2463.2463  0.482
2013 Mokhtari S, Lamar ZS, Booth C, Marini F, Porada CD, Almeida-Porada G. CD166+CD34+ Cells Exhibit Marked Functional Differences During Fetal and Adult Life Blood. 122: 2435-2435. DOI: 10.1182/Blood.V122.21.2435.2435  0.592
2012 Porada CD, Almeida-Porada G. Treatment of Hemophilia A in Utero and Postnatally using Sheep as a Model for Cell and Gene Delivery. Journal of Genetic Syndromes & Gene Therapy. PMID 23264887 DOI: 10.4172/2157-7412.S1-011  0.624
2012 Zakas PM, Gangadharan B, Almeida-Porada G, Porada CD, Spencer HT, Doering CB. Development and characterization of recombinant ovine coagulation factor VIII. Plos One. 7: e49481. PMID 23152911 DOI: 10.1371/Journal.Pone.0049481  0.602
2012 Soland MA, Bego MG, Colletti E, Porada CD, Zanjani ED, St Jeor S, Almeida-Porada G. Modulation of human mesenchymal stem cell immunogenicity through forced expression of human cytomegalovirus us proteins. Plos One. 7: e36163. PMID 22666319 DOI: 10.1371/Journal.Pone.0036163  0.675
2012 Wood JA, Colletti E, Mead LE, Ingram D, Porada CD, Zanjani ED, Yoder MC, Almeida-Porada G. Distinct contribution of human cord blood-derived endothelial colony forming cells to liver and gut in a fetal sheep model. Hepatology (Baltimore, Md.). 56: 1086-96. PMID 22488442 DOI: 10.1002/Hep.25753  0.68
2012 Ozturk F, Park PJ, Tellez J, Colletti E, Eiden MV, Almeida-Porada G, Porada CD. Expression levels of the PiT-2 receptor explain, in part, the gestational age-dependent alterations in transduction efficiency after in utero retroviral-mediated gene transfer. The Journal of Gene Medicine. 14: 169-81. PMID 22262359 DOI: 10.1002/Jgm.2607  0.788
2012 Soland M, Keyes L, Porada CD, Jeor SS, Almeida-Porada G. Niche Perivascular Stromal Cells As a Potential Reservoir and a Source of HCMV Reactivation Blood. 120: 3464-3464. DOI: 10.1182/Blood.V120.21.3464.3464  0.655
2012 Greenfield K, Mokhtari S, Haug M, Porada CD, Almeida-Porada G. Identification and Phenotypic Characterization of a Subpopulation of Acute Myelogenous Leukemia (AML) Cells with Increased Plastic Adherence. Blood. 120: 2556-2556. DOI: 10.1182/Blood.V120.21.2556.2556  0.624
2012 Mokhtari S, Colletti E, Porada CD, Almeida-Porada G. Origin and Characterization of CD166+ Cells During Human Marrow Ontogeny Blood. 120: 1252-1252. DOI: 10.1182/Blood.V120.21.1252.1252  0.632
2012 Shaw S, David A, Blundell M, Howe S, Pipino C, Maghsoudlou P, Lee K, Atala A, Porada C, Thrasher A, Coppi PD. Haematopoietic stem cells derived from sheep and human amniotic fluid engraft after transplantation Archives of Disease in Childhood-Fetal and Neonatal Edition. 97. DOI: 10.1136/Fetalneonatal-2012-301809.2  0.488
2011 Porada CD, Sanada C, Kuo CJ, Colletti E, Mandeville W, Hasenau J, Zanjani ED, Moot R, Doering C, Spencer HT, Almeida-Porada G. Phenotypic correction of hemophilia A in sheep by postnatal intraperitoneal transplantation of FVIII-expressing MSC. Experimental Hematology. 39: 1124-1135.e4. PMID 21906573 DOI: 10.1016/J.Exphem.2011.09.001  0.637
2011 Zakas PM, Gangadharan B, Almeida-Porada G, Porada CD, Spencer HT, Doering CB. Development and Characterization of Recombinant Ovine Factor VIII Blood. 118: 1193-1193. DOI: 10.1182/Blood.V118.21.1193.1193  0.588
2010 Porada CD, Almeida-Porada G. Mesenchymal stem cells as therapeutics and vehicles for gene and drug delivery. Advanced Drug Delivery Reviews. 62: 1156-66. PMID 20828588 DOI: 10.1016/J.Addr.2010.08.010  0.651
2010 Almeida-Porada G, Zanjani ED, Porada CD. Bone marrow stem cells and liver regeneration. Experimental Hematology. 38: 574-80. PMID 20417684 DOI: 10.1016/J.Exphem.2010.04.007  0.65
2010 Goodrich AD, Ersek A, Varain NM, Groza D, Cenariu M, Thain DS, Almeida-Porada G, Porada CD, Zanjani ED. In vivo generation of beta-cell-like cells from CD34(+) cells differentiated from human embryonic stem cells. Experimental Hematology. 38: 516-525.e4. PMID 20227460 DOI: 10.1016/J.Exphem.2010.03.002  0.685
2010 Ersek A, Pixley JS, Goodrich AD, Porada CD, Almeida-Porada G, Thain DS, Zanjani ED. Persistent circulating human insulin in sheep transplanted in utero with human mesenchymal stem cells. Experimental Hematology. 38: 311-20. PMID 20170708 DOI: 10.1016/J.Exphem.2010.02.005  0.666
2010 Porada CD, Sanada C, Long CR, Wood JA, Desai J, Frederick N, Millsap L, Bormann C, Menges SL, Hanna C, Flores-Foxworth G, Shin T, Westhusin ME, Liu W, Glimp H, et al. Clinical and molecular characterization of a re-established line of sheep exhibiting hemophilia A. Journal of Thrombosis and Haemostasis : Jth. 8: 276-85. PMID 19943872 DOI: 10.1111/J.1538-7836.2009.03697.X  0.574
2010 Colletti E, Mokhtari S, Sanada C, Zanjani ED, Porada CD, Almeida-Porada G. Timing of Mesenchymal Stem Cell Co-Transplantation and Site of Bone Engraftment Determine Levels of Hematopoietic Engraftment and Contribution of HSC to the Bone Niche Blood. 116: 940-940. DOI: 10.1182/Blood.V116.21.940.940  0.661
2010 Jeanblanc C, Colletti EJ, Porada CD, Almeida-Porada G, Zanjani E. Successful In Utero Hematopoietic Stem Cell Transplantation (IUHSCT) Likely Depends on Niche Maturity, Recipient/Donor MHC Compatibility and Donor Cell Origin Blood. 116: 574-574. DOI: 10.1182/Blood.V116.21.574.574  0.66
2010 Tellez J, Finn JD, Tschernia N, Almeida-Porada G, Arruda V, Porada CD. Naturally-Occurring Antibodies to Human AAV In Sheep: A New Large Animal Model for Immune Aspects of AAV Gene Transfer. Blood. 116: 3762-3762. DOI: 10.1182/Blood.V116.21.3762.3762  0.793
2010 Colletti EJ, Soland M, Jeor SS, Zanjani ED, Porada CD, Almeida-Porada G. Genetic Modification of Human Mesenchymal Stem Cells Enables Contribution to the Cardiac Progenitor Pool and Developing Myocardium In Vivo. Blood. 116: 3730-3730. DOI: 10.1182/Blood.V116.21.3730.3730  0.665
2010 Porada C, Sanada C, Kuo E, Colletti E, Moot R, Doering C, Spencer HT, Almeida-Porada G. Phenotypic Correction of Hemophilia A by Postnatal Intraperitoneal Transplantation of FVIII-Expressing MSC Blood. 116: 249-249. DOI: 10.1182/Blood.V116.21.249.249  0.662
2010 Sanada C, Colletti EJ, Soland M, Kuo C, Porada CD, Almeida-Porada G. Endogenous Expression of Functional Factor VIII by Human Mesenchymal Stem Cells In Culture Blood. 116: 2216-2216. DOI: 10.1182/Blood.V116.21.2216.2216  0.673
2010 Soland M, Colletti EJ, Bego M, Sanada C, Porada CD, Zanjani ED, Jeor SS, Almeida-Porada G. Modulation of Mesenchymal Stem Cell MHC-I Complex Increases Engraftment In Vivo. Blood. 116: 1457-1457. DOI: 10.1182/Blood.V116.21.1457.1457  0.627
2010 Donepudi S, Porada CD, Zanjani E, Almeida-Porada G. Abstract 538: Mesenchymal stem cell subset prevents cycling of KG1a leukemic cells by cell-cell interaction Cancer Research. 70: 538-538. DOI: 10.1158/1538-7445.Am10-538  0.649
2009 Colletti EJ, Airey JA, Liu W, Simmons PJ, Zanjani ED, Porada CD, Almeida-Porada G. Generation of tissue-specific cells from MSC does not require fusion or donor-to-host mitochondrial/membrane transfer. Stem Cell Research. 2: 125-38. PMID 19383418 DOI: 10.1016/J.Scr.2008.08.002  0.674
2009 Park PJ, Colletti E, Ozturk F, Wood JA, Tellez J, Almeida-Porada G, Porada C. Factors determining the risk of inadvertent retroviral transduction of male germ cells after in utero gene transfer in sheep. Human Gene Therapy. 20: 201-15. PMID 19301473 DOI: 10.1089/Hum.2007.120  0.791
2009 da Silva CL, Gonçalves R, Porada CD, Ascensão JL, Zanjani ED, Cabral JM, Almeida-Porada G. Differences amid bone marrow and cord blood hematopoietic stem/progenitor cell division kinetics. Journal of Cellular Physiology. 220: 102-11. PMID 19277981 DOI: 10.1002/Jcp.21736  0.628
2009 Yamagami T, Porada CD, Pardini RS, Zanjani ED, Almeida-Porada G. Docosahexaenoic acid induces dose dependent cell death in an early undifferentiated subtype of acute myeloid leukemia cell line. Cancer Biology & Therapy. 8: 331-7. PMID 19197149 DOI: 10.4161/Cbt.8.4.7334  0.617
2009 Colletti E, ElShabrawy D, Zanjani ED, Porada CD, Almeida-Porada G. Characterization of the Human Hematopoietic Niche During Ontogeny. Blood. 114: 3626-3626. DOI: 10.1182/Blood.V114.22.3626.3626  0.616
2009 Jeanblanc CM, Colletti E, Porada CD, Almeida-Porada G, Zanjani ED. Defining the Development of Receptive Niches for in Utero Transplantation of Hematopoietic Stem Cells. Blood. 114: 3527-3527. DOI: 10.1182/Blood.V114.22.3527.3527  0.681
2008 Porada CD, Harrison-Findik DD, Sanada C, Valiente V, Thain D, Simmons PJ, Almeida-Porada G, Zanjani ED. Development and characterization of a novel CD34 monoclonal antibody that identifies sheep hematopoietic stem/progenitor cells. Experimental Hematology. 36: 1739-49. PMID 19007686 DOI: 10.1182/Blood.V110.11.4909.4909  0.668
2008 Colletti E, Lindstedt S, Park PJ, Almeida-Porada G, Porada CD. Early fetal gene delivery utilizes both central and peripheral mechanisms of tolerance induction. Experimental Hematology. 36: 816-22. PMID 18400364 DOI: 10.1016/J.Exphem.2008.02.007  0.717
2008 Frias AM, Porada CD, Crapnell KB, Cabral JM, Zanjani ED, Almeida-Porada G. Generation of functional natural killer and dendritic cells in a human stromal-based serum-free culture system designed for cord blood expansion. Experimental Hematology. 36: 61-8. PMID 18155552 DOI: 10.1016/J.Exphem.2007.08.031  0.632
2008 Colletti E, ElShabrawy D, Zanjani ED, Porada CD, Almeida-Porada G. Tales from the Crypt: Mesenchymal Stem Cells for Replenishing the Intestinal Stem Cell Pool Blood. 112: 390-390. DOI: 10.1182/Blood.V112.11.390.390  0.69
2008 Yamagami T, Colletti E, Wiendl H, Zanjani E, Porada CD, Almeida-Porada G. Expression of Molecules Involved in Fetal-Maternal Tolerance Allows Human Mesenchymal Stem Cells to Engraft at High Levels across Immunologic Barriers Blood. 112: 3480-3480. DOI: 10.1182/Blood.V112.11.3480.3480  0.636
2008 Sanada C, Wood JA, Liu W, Lozier JN, Almeida-Porada G, Porada CD. A Frame Shift-Induced Stop Codon Causes Hemophilia a in Sheep. Blood. 112: 3378-3378. DOI: 10.1182/Blood.V112.11.3378.3378  0.599
2008 Soland M, Bego M, Porada CD, Zanjani ED, Jeor SS, Almeida-Porada G. Modulation of Mesenchymal Stem Cell Immunogenicity through Forced Expression of Human Cytomegalovirus Proteins Blood. 112: 2416-2416. DOI: 10.1182/Blood.V112.11.2416.2416  0.663
2008 Wood JA, Colletti E, Mead LE, Ingram DA, Porada CD, Zanjani E, Yoder MC, Almeida-Porada G. Human Endothelial Progenitor Cells: A Novel and Promising Cellular Therapy for Regenerating Intestinal Mucosa. Blood. 112: 1883-1883. DOI: 10.1182/Blood.V112.11.1883.1883  0.64
2008 Almeida-Porada G, Porada CD, LeBlanc C, Ascensao JL, McNiece IK, Zanjani ED. MHC-Matching at 5 Loci Results in Higher Levels of Engraftment of Allogeneic Cord Blood (CB) Hematopoietic Stem Cells (HSC) Following Neonatal Transplantation. Blood. 112: 1246-1246. DOI: 10.1182/Blood.V112.11.1246.1246  0.65
2008 Bormann C, Long C, Menges S, Hanna C, Foxworth G, Westhusin M, Pliska V, Stranzinger G, Joerg H, Glimp H, Millsap L, Porada C, Almedia-Porada G, Kraemer D. 145 REESTABLISHMENT OF AN EXTINCT STRAIN OF SHEEP UTILIZING ASSISTED REPRODUCTIVE TECHNOLOGIES Reproduction, Fertility and Development. 20: 153. DOI: 10.1071/Rdv20N1Ab145  0.319
2007 Almeida-Porada G, Porada C, Gupta N, Torabi A, Thain D, Zanjani ED. The human-sheep chimeras as a model for human stem cell mobilization and evaluation of hematopoietic grafts' potential. Experimental Hematology. 35: 1594-600. PMID 17889724 DOI: 10.1016/J.Exphem.2007.07.009  0.68
2007 Chamberlain J, Yamagami T, Colletti E, Theise ND, Desai J, Frias A, Pixley J, Zanjani ED, Porada CD, Almeida-Porada G. Efficient generation of human hepatocytes by the intrahepatic delivery of clonal human mesenchymal stem cells in fetal sheep. Hepatology (Baltimore, Md.). 46: 1935-45. PMID 17705296 DOI: 10.1002/Hep.21899  0.671
2007 Colletti EJ, Airey JA, Zanjani ED, Porada CD, Almeida-Porada G. Human Mesenchymal Stem Cells Differentiate Promptly into Tissue-Specific Cell Types without Cell Fusion, Mitochondrial or Membrane Vesicular Transfer in Fetal Sheep. Blood. 110: 436-436. DOI: 10.1182/Blood.V110.11.436.436  0.661
2007 Wood JA, Colletti E, Mead LE, Ingram DA, Porada CD, Zanjani ED, Yoder MC, Almeida-Porada G. Human Cord Blood-Derived Endothelial Progenitor Cells Engraft Following In Utero Transplantation, Integrate into the Developing Cytoarchitecture and Contribute to Ongoing Vasculogenesis. Blood. 110: 3714-3714. DOI: 10.1182/Blood.V110.11.3714.3714  0.631
2007 Colletti E, Lindsted S, Park P, Almeida-Porada G, Porada CD. Gene Transfer Early in Gestation Results in Transduction of Key Cellular Mediators of Both Central and Peripheral Immune Tolerance. Blood. 110: 2585-2585. DOI: 10.1182/Blood.V110.11.2585.2585  0.718
2007 Garol NJ, Yamagami T, Osborne C, Porada CD, Zanjani ED, Almeida-Porada G. Tissue-Specific Molecular Signature May Explain Differentiative Bias of Human MSC from Different Tissues. Blood. 110: 1918-1918. DOI: 10.1182/Blood.V110.11.1918.1918  0.64
2007 Porada CD, Almeida-Porada G, Zanjani ED. Development and Validation of a Novel, High-Throughput Colony-Forming Assay That Allows Simultaneous Detection and Quantitation of Seven Primitive Sheep Hematopoietic Populations. Blood. 110: 1221-1221. DOI: 10.1182/Blood.V110.11.1221.1221  0.653
2007 Yamagami T, Sanada C, Wiendl H, Zanjani ED, Porada CD, Almeida-Porada G. Expression of HLA-G1 and G5 Enables Human Mesenchymal Stem Cells To Engraft at High Levels across Xenogeneic Barriers Following Transplantation into Immunocompetent Recipients. Blood. 110: 1195-1195. DOI: 10.1182/Blood.V110.11.1195.1195  0.629
2007 Almeida-Porada G, Desai J, Long C, Westhusin M, Pliska V, Stranzinger G, Joerg H, Thain D, Glimp H, Kraemer D, Porada CD. Re-Establishment and Characterization of an Extinct Line of Sheep with a Spontaneous Bleeding Disorder That Closely Recapitulates Human Hemophilia A. Blood. 110: 1144-1144. DOI: 10.1182/Blood.V110.11.1144.1144  0.627
2006 Porada CD, Zanjani ED, Almeida-Porad G. Adult mesenchymal stem cells: a pluripotent population with multiple applications. Current Stem Cell Research & Therapy. 1: 365-9. PMID 18220880 DOI: 10.2174/157488806778226821  0.473
2006 Ersek A, Goodrich AD, Porada CD, Pixley JS, Almeida-Porada MG, Zanjani ED. Human Pancreatic Mesenchymal Stem Cells Produce Blood in the Non-Injury Fetal Sheep Model. Blood. 108: 2558-2558. DOI: 10.1182/Blood.V108.11.2558.2558  0.484
2006 Bormann C, Long C, Menges S, Hanna C, Foxworth G, Shin T, Westhusin M, Pliska V, Stranzinger G, Joerg H, Glimp H, Millsap L, Porada C, Almeida-Porada G, Kraemer D. 187 RE-ESTABLISHMENT OF AN EXTINCT STRAIN OF SHEEP FROM A LIMITED SUPPLY OF FROZEN SEMEN Reproduction, Fertility and Development. 18: 201. DOI: 10.1071/Rdv18N2Ab187  0.551
2006 Almeida-Porada G, Porada CD, Zanjani ED. A Large Animal Non-Injury Model for Study of Human Stem Cell Plasticity Stem Cell Transplantation: Biology, Processing, and Therapy. 119-132. DOI: 10.1002/3527608745.ch8  0.634
2005 Porada CD, Park PJ, Tellez J, Ozturk F, Glimp HA, Almeida-Porada G, Zanjani ED. Male germ-line cells are at risk following direct-injection retroviral-mediated gene transfer in utero. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 754-62. PMID 16084775 DOI: 10.1016/J.Ymthe.2005.05.011  0.795
2005 Almeida-Porada G, Crappnell K, Porada C, Benoit B, Nakauchi H, Quesenberry P, Zanjani ED. In vivo haematopoietic potential of human neural stem cells British Journal of Haematology. 130: 276-283. PMID 16029457 DOI: 10.1111/J.1365-2141.2005.05588.X  0.665
2005 Lucas ML, Seidel NE, Porada CD, Quigley JG, Anderson SM, Malech HL, Abkowitz JL, Zanjani ED, Bodine DM. Improved transduction of human sheep repopulating cells by retrovirus vectors pseudotyped with feline leukemia virus type C or RD114 envelopes. Blood. 106: 51-8. PMID 15774617 DOI: 10.1182/Blood-2004-11-4491  0.438
2005 Porada CD, Park PJ, Almeida-Porada G, Liu W, Ozturk F, Glimp HA, Zanjani ED. Gestational age of recipient determines pattern and level of transgene expression following in utero retroviral gene transfer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 284-93. PMID 15668140 DOI: 10.1016/J.Ymthe.2004.09.009  0.769
2005 Mazhari S, Desai J, Chamberlain J, Porada C, Zanjani ED, Almeida-Porada G. Proteomic Analysis Reveals Intrinsic Differences between Phenotypically Identical Mesenchymal Stem Cells. Blood. 106: 395-395. DOI: 10.1182/Blood.V106.11.395.395  0.639
2005 Ozturk F, Park P, Tellez J, Anderson WB, Eiden M, Zanjani ED, Almeida-Porada G, Porada CD. 750. Expression Levels of the Amphotropic Receptor May Explain Gestational Age-Dependence of Tissue Transduction in Fetal Sheep Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.290  0.784
2004 Porada GA, Porada C, Zanjani ED. The fetal sheep: a unique model system for assessing the full differentiative potential of human stem cells. Yonsei Medical Journal. 45: 7-14. PMID 15250043 DOI: 10.3349/Ymj.2004.45.Suppl.7  0.491
2004 Almeida-Porada G, Porada CD, Chamberlain J, Torabi A, Zanjani ED. Formation of human hepatocytes by human hematopoietic stem cells in sheep. Blood. 104: 2582-90. PMID 15231580 DOI: 10.1182/Blood-2004-01-0259  0.689
2004 Airey JA, Almeida-Porada G, Colletti EJ, Porada CD, Chamberlain J, Movsesian M, Sutko JL, Zanjani ED. Human mesenchymal stem cells form Purkinje fibers in fetal sheep heart. Circulation. 109: 1401-7. PMID 15023887 DOI: 10.1161/01.Cir.0000124222.16321.26  0.622
2004 Almeida-Porada G, Porada C, Zanjani ED. Plasticity of human stem cells in the fetal sheep model of human stem cell transplantation. International Journal of Hematology. 79: 1-6. PMID 14979471 DOI: 10.1007/Bf02983526  0.68
2004 Porada CD, Park P, Almeida-Porada G, Zanjani ED. The sheep model of in utero gene therapy. Fetal Diagnosis and Therapy. 19: 23-30. PMID 14646413 DOI: 10.1159/000074255  0.744
2004 Chamberlain J, Porada CD, Frias A, Yamagami T, Zanjani ED, Almeida-Porada G. Tissue Availability of Donor Mesenchymal Stem Cells Determines the Degree of Plasticity Following Transplantation in a Non-Injury Model. Blood. 104: 676-676. DOI: 10.1182/Blood.V104.11.676.676  0.674
2004 Frias A, Porada CD, Crapnell KB, Cabral JM, Zanjani ED, Almeida-Porada G. Ex-Vivo Generation and Expansion of Both Lymphoid and Myeloid Lineages from Human Cord Blood (CB) HSC Using a Serum-Free Human Mesenchymal Stem Cell Based Culture System. Blood. 104: 2888-2888. DOI: 10.1182/Blood.V104.11.2888.2888  0.611
2004 Park PJ, Tellez J, Almeida-Porada G, Zanjani ED, Porada CD. 1052. Male Germline Cells Appear To Be at Risk Following Direct Injection Gene Transfer In Utero Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.997  0.816
2002 Almeida-Porada G, El Shabrawy D, Porada C, Zanjani ED. Differentiative potential of human metanephric mesenchymal cells. Experimental Hematology. 30: 1454-62. PMID 12482508 DOI: 10.1016/S0301-472X(02)00967-0  0.646
2002 Tsai EJ, Malech HL, Kirby MR, Hsu AP, Seidel NE, Porada CD, Zanjani ED, Bodine DM, Puck JM. Retroviral transduction of IL2RG into CD34(+) cells from X-linked severe combined immunodeficiency patients permits human T- and B-cell development in sheep chimeras. Blood. 100: 72-9. PMID 12070011 DOI: 10.1182/Blood.V100.1.72  0.452
2002 Porada CD, Tran ND, Almeida-Porada G, Glimp HA, Pixley JS, Zhao Y, Anderson WF, Zanjani ED. Transduction of long-term-engrafting human hematopoietic stem cells by retroviral vectors. Human Gene Therapy. 13: 867-79. PMID 11975852 DOI: 10.1089/10430340252899037  0.696
2001 Almeida-Porada G, Porada C, Zanjani ED. Adult stem cell plasticity and methods of detection Reviews in Clinical and Experimental Hematology. 5: 26-41. PMID 11486730 DOI: 10.1046/J.1468-0734.2001.00027.X  0.664
2001 Tran ND, Porada CD, Almeida-Porada G, Glimp HA, French Anderson W, Zanjani ED. Induction of stable prenatal tolerance to β-galactosidase by in utero gene transfer into preimmune sheep fetuses Blood. 97: 3417-3423. PMID 11369632 DOI: 10.1182/Blood.V97.11.3417  0.652
2000 Almeida-Porada G, Porada CD, Tran N, Zanjani ED. Cotransplantation of human stromal cell progenitors into preimmune fetal sheep results in early appearance of human donor cells in circulation and boosts cell levels in bone marrow at later time points after transplantation Blood. 95: 3620-3627. PMID 10828053 DOI: 10.1182/Blood.V95.11.3620.011K02_3620_3627  0.693
2000 Tran ND, Porada CD, Zhao Y, Almeida-Porada G, Anderson WF, Zanjani ED. In utero transfer and expression of exogenous genes in sheep Experimental Hematology. 28: 17-30. PMID 10658673 DOI: 10.1016/S0301-472X(99)00133-2  0.608
2000 Almeida-Porada G, Crapnell K, Porada C, Benoit B, Nakauchi H, Quesenberry P, Zanjani E. In vivo hematopoietic potential of human neuronal stem cells Experimental Hematology. 28: 61. DOI: 10.1016/S0301-472X(00)00278-2  0.642
2000 Porada CD, Tran ND, Zhao Y, Anderson WF, Zanjani ED. Neonatal gene therapytransfer and expression of exogenous genes in neonatal sheep following direct injection of retroviral vectors into the bone marrow space Experimental Hematology. 28: 642-650. DOI: 10.1016/S0301-472X(00)00158-2  0.377
1999 Zanjani ED, Almeida-Porada G, Livingston AG, Porada CD, Ogawa M. Engraftment and multilineage expression of human bone marrow CD34- cells in vivo Annals of the New York Academy of Sciences. 872: 220-232. PMID 10372125 DOI: 10.1111/J.1749-6632.1999.Tb08467.X  0.666
1998 Pixley JS, Zanjani ED, Shaft DM, Porada C, Mackintosh FR. Prolonged hematopoietic chimerism in normal mice transplanted in utero with human hematopoietic stem cells. Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology. 66: 230-9. PMID 9732238 DOI: 10.1159/000028028  0.462
1998 Porada CD, Tran N, Eglitis M, Moen RC, Troutman L, Flake AW, Zhao Y, Anderson WF, Zanjani ED. In utero gene therapy: Transfer and long-term expression of the bacterial neo(r) gene in sheep after direct injection of retroviral vectors into preimmune fetuses Human Gene Therapy. 9: 1571-1585. PMID 9694156 DOI: 10.1089/Hum.1998.9.11-1571  0.406
1997 Almeida-Porada G, Porada CD, Shanley JD, Ascensao JL. Altered production of GM-CSF and IL-8 in cytomegalovirus-infected, IL- 1-primed umbilical cord endothelial cells Experimental Hematology. 25: 1278-1285. PMID 9357972  0.504
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