| Year |
Citation |
Score |
| 2019 |
Hoang TT, Johnson DA, Raines RT, Johnson JA. Angiogenin activates the astrocytic Nrf2/ARE pathway and thereby protects murine neurons from oxidative stress. The Journal of Biological Chemistry. PMID 31431502 DOI: 10.1074/Jbc.Ra119.008491 |
0.426 |
|
| 2016 |
Lee LY, Harberg C, Matkowskyj KA, Cook S, Roenneburg D, Werner S, Johnson DA, Johnson JA, Foley DP. Cell-Specific Over-activation of Nrf2-mediated Gene Expression in Myeloid Cells Decreases Hepatic Ischemia Reperfusion Injury. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. PMID 27113842 DOI: 10.1002/Lt.24473 |
0.322 |
|
| 2016 |
Johnson J, Johnson D, Brautigam H. A22 Genetic tools to validate and measure NRF2 in HD Journal of Neurology, Neurosurgery, and Psychiatry. 87. DOI: 10.1136/Jnnp-2016-314597.22 |
0.484 |
|
| 2015 |
Johnson DA, Johnson JA. Nrf2-a therapeutic target for the treatment of neurodegenerative diseases. Free Radical Biology & Medicine. PMID 26281945 DOI: 10.1016/J.Freeradbiomed.2015.07.147 |
0.418 |
|
| 2015 |
Joshi G, Gan KA, Johnson DA, Johnson JA. Increased Alzheimer's disease-like pathology in the APP/ PS1ΔE9 mouse model lacking Nrf2 through modulation of autophagy. Neurobiology of Aging. 36: 664-79. PMID 25316599 DOI: 10.1016/J.Neurobiolaging.2014.09.004 |
0.349 |
|
| 2014 |
Kulkarni SR, Donepudi AC, Xu J, Wei W, Cheng QC, Driscoll MV, Johnson DA, Johnson JA, Li X, Slitt AL. Fasting induces nuclear factor E2-related factor 2 and ATP-binding Cassette transporters via protein kinase A and Sirtuin-1 in mouse and human. Antioxidants & Redox Signaling. 20: 15-30. PMID 23725046 DOI: 10.1089/Ars.2012.5082 |
0.447 |
|
| 2013 |
Wyche TP, Standiford M, Hou Y, Braun D, Johnson DA, Johnson JA, Bugni TS. Activation of the nuclear factor E2-related factor 2 pathway by novel natural products halomadurones A-D and a synthetic analogue. Marine Drugs. 11: 5089-99. PMID 24351907 DOI: 10.3390/Md11125089 |
0.336 |
|
| 2013 |
Swanson CR, Du E, Johnson DA, Johnson JA, Emborg ME. Neuroprotective Properties of a Novel Non-Thiazoledinedione Partial PPAR- γ Agonist against MPTP. Ppar Research. 2013: 582809. PMID 24223584 DOI: 10.1155/2013/582809 |
0.404 |
|
| 2013 |
Fischedick JT, Standiford M, Johnson DA, Johnson JA. Structure activity relationship of phenolic diterpenes from Salvia officinalis as activators of the nuclear factor E2-related factor 2 pathway. Bioorganic & Medicinal Chemistry. 21: 2618-22. PMID 23507152 DOI: 10.1016/J.Bmc.2013.02.019 |
0.419 |
|
| 2013 |
Vargas MR, Burton NC, Kutzke J, Gan L, Johnson DA, Schäfer M, Werner S, Johnson JA. Absence of Nrf2 or its selective overexpression in neurons and muscle does not affect survival in ALS-linked mutant hSOD1 mouse models. Plos One. 8: e56625. PMID 23418589 DOI: 10.1371/Journal.Pone.0056625 |
0.388 |
|
| 2013 |
Zhang L, Johnson D, Johnson JA. Deletion of Nrf2 impairs functional recovery, reduces clearance of myelin debris and decreases axonal remyelination after peripheral nerve injury. Neurobiology of Disease. 54: 329-38. PMID 23328769 DOI: 10.1016/J.Nbd.2013.01.003 |
0.336 |
|
| 2013 |
Béraud D, Hathaway HA, Trecki J, Chasovskikh S, Johnson DA, Johnson JA, Federoff HJ, Shimoji M, Mhyre TR, Maguire-Zeiss KA. Microglial activation and antioxidant responses induced by the Parkinson's disease protein α-synuclein. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 8: 94-117. PMID 23054368 DOI: 10.1007/S11481-012-9401-0 |
0.407 |
|
| 2012 |
Gan L, Vargas MR, Johnson DA, Johnson JA. Astrocyte-specific overexpression of Nrf2 delays motor pathology and synuclein aggregation throughout the CNS in the alpha-synuclein mutant (A53T) mouse model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 17775-87. PMID 23223297 DOI: 10.1523/Jneurosci.3049-12.2012 |
0.451 |
|
| 2012 |
Williamson TP, Amirahmadi S, Joshi G, Kaludov NK, Martinov MN, Johnson DA, Johnson JA. Discovery of potent, novel Nrf2 inducers via quantum modeling, virtual screening, and in vitro experimental validation. Chemical Biology & Drug Design. 80: 810-20. PMID 22925725 DOI: 10.1111/Cbdd.12040 |
0.4 |
|
| 2012 |
Fischedick JT, Standiford M, Johnson DA, De Vos RC, Todorović S, Banjanac T, Verpoorte R, Johnson JA. Activation of antioxidant response element in mouse primary cortical cultures with sesquiterpene lactones isolated from Tanacetum parthenium. Planta Medica. 78: 1725-30. PMID 22923197 DOI: 10.1055/S-0032-1315241 |
0.391 |
|
| 2012 |
LaPash Daniels CM, Austin EV, Rockney DE, Jacka EM, Hagemann TL, Johnson DA, Johnson JA, Messing A. Beneficial effects of Nrf2 overexpression in a mouse model of Alexander disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 10507-15. PMID 22855800 DOI: 10.1523/Jneurosci.1494-12.2012 |
0.44 |
|
| 2012 |
Williamson TP, Johnson DA, Johnson JA. Activation of the Nrf2-ARE pathway by siRNA knockdown of Keap1 reduces oxidative stress and provides partial protection from MPTP-mediated neurotoxicity. Neurotoxicology. 33: 272-9. PMID 22342405 DOI: 10.1016/J.Neuro.2012.01.015 |
0.477 |
|
| 2012 |
Foley DP, Nelson SE, Johnson DA, Johnson JA. Induction of the Nrf2-Antioxidant Response Element Pathway (ARE) in Hepatic Stellate Cells Protects Hepatocytes from Oxidative Stress-Induced Injury Journal of Surgical Research. 172: 205-206. DOI: 10.1016/J.Jss.2011.11.282 |
0.383 |
|
| 2011 |
Vargas MR, Johnson DA, Johnson JA. Decreased glutathione accelerates neurological deficit and mitochondrial pathology in familial ALS-linked hSOD1(G93A) mice model. Neurobiology of Disease. 43: 543-51. PMID 21600285 DOI: 10.1016/J.Nbd.2011.04.025 |
0.377 |
|
| 2010 |
Schäfer M, Dütsch S, auf dem Keller U, Navid F, Schwarz A, Johnson DA, Johnson JA, Werner S. Nrf2 establishes a glutathione-mediated gradient of UVB cytoprotection in the epidermis. Genes & Development. 24: 1045-58. PMID 20478997 DOI: 10.1101/Gad.568810 |
0.444 |
|
| 2010 |
Calkins MJ, Townsend JA, Johnson DA, Johnson JA. Cystamine protects from 3-nitropropionic acid lesioning via induction of nf-e2 related factor 2 mediated transcription. Experimental Neurology. 224: 307-17. PMID 20406637 DOI: 10.1016/J.Expneurol.2010.04.008 |
0.423 |
|
| 2010 |
Gan L, Johnson DA, Johnson JA. Keap1-Nrf2 activation in the presence and absence of DJ-1. The European Journal of Neuroscience. 31: 967-77. PMID 20377612 DOI: 10.1111/J.1460-9568.2010.07138.X |
0.517 |
|
| 2010 |
Calkins MJ, Vargas MR, Johnson DA, Johnson JA. Astrocyte-specific overexpression of Nrf2 protects striatal neurons from mitochondrial complex II inhibition. Toxicological Sciences : An Official Journal of the Society of Toxicology. 115: 557-68. PMID 20211941 DOI: 10.1093/Toxsci/Kfq072 |
0.442 |
|
| 2010 |
Son TG, Camandola S, Arumugam TV, Cutler RG, Telljohann RS, Mughal MR, Moore TA, Luo W, Yu QS, Johnson DA, Johnson JA, Greig NH, Mattson MP. Plumbagin, a novel Nrf2/ARE activator, protects against cerebral ischemia. Journal of Neurochemistry. 112: 1316-26. PMID 20028456 DOI: 10.1111/J.1471-4159.2009.06552.X |
0.479 |
|
| 2010 |
Johnson DA, Amirahmadi S, Ward C, Fabry Z, Johnson JA. The absence of the pro-antioxidant transcription factor Nrf2 exacerbates experimental autoimmune encephalomyelitis. Toxicological Sciences : An Official Journal of the Society of Toxicology. 114: 237-46. PMID 19910389 DOI: 10.1093/Toxsci/Kfp274 |
0.614 |
|
| 2009 |
Cho W, Hagemann TL, Johnson DA, Johnson JA, Messing A. Dual transgenic reporter mice as a tool for monitoring expression of glial fibrillary acidic protein. Journal of Neurochemistry. 110: 343-51. PMID 19457099 DOI: 10.1111/J.1471-4159.2009.06146.X |
0.359 |
|
| 2009 |
Chen PC, Vargas MR, Pani AK, Smeyne RJ, Johnson DA, Kan YW, Johnson JA. Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte. Proceedings of the National Academy of Sciences of the United States of America. 106: 2933-8. PMID 19196989 DOI: 10.1073/Pnas.0813361106 |
0.49 |
|
| 2009 |
Calkins MJ, Johnson DA, Townsend JA, Vargas MR, Dowell JA, Williamson TP, Kraft AD, Lee JM, Li J, Johnson JA. The Nrf2/ARE pathway as a potential therapeutic target in neurodegenerative disease. Antioxidants & Redox Signaling. 11: 497-508. PMID 18717629 DOI: 10.1089/Ars.2008.2242 |
0.419 |
|
| 2008 |
Johnson JA, Johnson DA, Kraft AD, Calkins MJ, Jakel RJ, Vargas MR, Chen PC. The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration. Annals of the New York Academy of Sciences. 1147: 61-9. PMID 19076431 DOI: 10.1196/Annals.1427.036 |
0.508 |
|
| 2008 |
Vargas MR, Johnson DA, Sirkis DW, Messing A, Johnson JA. Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13574-81. PMID 19074031 DOI: 10.1523/Jneurosci.4099-08.2008 |
0.403 |
|
| 2008 |
Dostalek M, Hardy KD, Milne GL, Morrow JD, Chen C, Gonzalez FJ, Gu J, Ding X, Johnson DA, Johnson JA, Martin MV, Guengerich FP. Development of oxidative stress by cytochrome P450 induction in rodents is selective for barbiturates and related to loss of pyridine nucleotide-dependent protective systems. The Journal of Biological Chemistry. 283: 17147-57. PMID 18442974 DOI: 10.1074/Jbc.M802447200 |
0.378 |
|
| 2008 |
Burk RF, Hill KE, Nakayama A, Mostert V, Levander XA, Motley AK, Johnson DA, Johnson JA, Freeman ML, Austin LM. Selenium deficiency activates mouse liver Nrf2-ARE but vitamin E deficiency does not. Free Radical Biology & Medicine. 44: 1617-23. PMID 18279678 DOI: 10.1016/J.Freeradbiomed.2008.01.016 |
0.359 |
|
| 2007 |
Li J, Calkins MJ, Johnson DA, Johnson JA. Role of Nrf2-dependent ARE-driven antioxidant pathway in neuroprotection. Methods in Molecular Biology (Clifton, N.J.). 399: 67-78. PMID 18309926 DOI: 10.1007/978-1-59745-504-6_6 |
0.483 |
|
| 2007 |
Kraft AD, Resch JM, Johnson DA, Johnson JA. Activation of the Nrf2-ARE pathway in muscle and spinal cord during ALS-like pathology in mice expressing mutant SOD1. Experimental Neurology. 207: 107-17. PMID 17631292 DOI: 10.1016/J.Expneurol.2007.05.026 |
0.402 |
|
| 2007 |
Yates MS, Tauchi M, Katsuoka F, Flanders KC, Liby KT, Honda T, Gribble GW, Johnson DA, Johnson JA, Burton NC, Guilarte TR, Yamamoto M, Sporn MB, Kensler TW. Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes. Molecular Cancer Therapeutics. 6: 154-62. PMID 17237276 DOI: 10.1158/1535-7163.Mct-06-0516 |
0.391 |
|
| 2007 |
Durchdewald M, Beyer TA, Johnson DA, Johnson JA, Werner S, auf dem Keller U. Electrophilic chemicals but not UV irradiation or reactive oxygen species activate Nrf2 in keratinocytes in vitro and in vivo. The Journal of Investigative Dermatology. 127: 646-53. PMID 17008872 DOI: 10.1038/Sj.Jid.5700585 |
0.455 |
|
| 2006 |
Kraft AD, Lee JM, Johnson DA, Kan YW, Johnson JA. Neuronal sensitivity to kainic acid is dependent on the Nrf2-mediated actions of the antioxidant response element. Journal of Neurochemistry. 98: 1852-65. PMID 16945104 DOI: 10.1111/J.1471-4159.2006.04019.X |
0.452 |
|
| 2006 |
auf dem Keller U, Huber M, Beyer TA, Kümin A, Siemes C, Braun S, Bugnon P, Mitropoulos V, Johnson DA, Johnson JA, Hohl D, Werner S. Nrf transcription factors in keratinocytes are essential for skin tumor prevention but not for wound healing. Molecular and Cellular Biology. 26: 3773-84. PMID 16648473 DOI: 10.1128/Mcb.26.10.3773-3784.2006 |
0.4 |
|
| 2005 |
Hagemann TL, Gaeta SA, Smith MA, Johnson DA, Johnson JA, Messing A. Gene expression analysis in mice with elevated glial fibrillary acidic protein and Rosenthal fibers reveals a stress response followed by glial activation and neuronal dysfunction. Human Molecular Genetics. 14: 2443-58. PMID 16014634 DOI: 10.1093/Hmg/Ddi248 |
0.441 |
|
| 2005 |
Lee JM, Li J, Johnson DA, Stein TD, Kraft AD, Calkins MJ, Jakel RJ, Johnson JA. Nrf2, a multi-organ protector? Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1061-6. PMID 15985529 DOI: 10.1096/Fj.04-2591Hyp |
0.426 |
|
| 2005 |
Jakel RJ, Kern JT, Johnson DA, Johnson JA. Induction of the protective antioxidant response element pathway by 6-hydroxydopamine in vivo and in vitro. Toxicological Sciences : An Official Journal of the Society of Toxicology. 87: 176-86. PMID 15976186 DOI: 10.1093/Toxsci/Kfi241 |
0.467 |
|
| 2005 |
Li J, Spletter ML, Johnson DA, Wright LS, Svendsen CN, Johnson JA. Rotenone-induced caspase 9/3-independent and -dependent cell death in undifferentiated and differentiated human neural stem cells. Journal of Neurochemistry. 92: 462-76. PMID 15659217 DOI: 10.1111/J.1471-4159.2004.02872.X |
0.306 |
|
| 2005 |
Calkins MJ, Jakel RJ, Johnson DA, Chan K, Kan YW, Johnson JA. Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription. Proceedings of the National Academy of Sciences of the United States of America. 102: 244-9. PMID 15611470 DOI: 10.1073/Pnas.0408487101 |
0.452 |
|
| 2005 |
Li J, Johnson D, Calkins M, Wright L, Svendsen C, Johnson J. Stabilization of Nrf2 by tBHQ confers protection against oxidative stress-induced cell death in human neural stem cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 83: 313-28. PMID 15525690 DOI: 10.1093/Toxsci/Kfi027 |
0.433 |
|
| 2004 |
Li J, Lee JM, Johnson DA, Johnson JA. Antioxidant responsive element activation by quinones: antioxidant responsive element target genes, role of PI3 kinase in activation. Methods in Enzymology. 378: 238-58. PMID 15038973 DOI: 10.1016/S0076-6879(04)78019-2 |
0.408 |
|
| 2004 |
Kraft AD, Johnson DA, Johnson JA. Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 1101-12. PMID 14762128 DOI: 10.1523/Jneurosci.3817-03.2004 |
0.439 |
|
| 2003 |
Shih AY, Johnson DA, Wong G, Kraft AD, Jiang L, Erb H, Johnson JA, Murphy TH. Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3394-406. PMID 12716947 DOI: 10.1523/Jneurosci.23-08-03394.2003 |
0.458 |
|
| 2002 |
Johnson DA, Andrews GK, Xu W, Johnson JA. Activation of the antioxidant response element in primary cortical neuronal cultures derived from transgenic reporter mice. Journal of Neurochemistry. 81: 1233-41. PMID 12068071 DOI: 10.1046/J.1471-4159.2002.00913.X |
0.466 |
|
| 2001 |
Murphy TH, Yu J, Ng R, Johnson DA, Shen H, Honey CR, Johnson JA. Preferential expression of antioxidant response element mediated gene expression in astrocytes. Journal of Neurochemistry. 76: 1670-8. PMID 11259485 DOI: 10.1046/J.1471-4159.2001.00157.X |
0.419 |
|
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