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Jeffrey A. Hubbell, Ph.D. - Publications

Affiliations: 
2003 Eidgenössische Technische Hochschule Zürich, Zürich, ZH, Switzerland 
 2003-2014 École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland 
 2014- University of Chicago, Chicago, IL 
Area:
biomaterials and protein engineering
Website:
https://newfaculty.uchicago.edu/page/jeffrey-hubbell
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Year Citation  Score
2023 Kang S, Mansurov A, Kurtanich T, Chun HR, Slezak AJ, Volpatti LR, Chang K, Wang T, Alpar AT, Refvik KC, Hansen OI, Borjas GJ, Shim HN, Hultgren KT, Gomes S, ... ... Hubbell JA, et al. Engineered IL-7 synergizes with IL-12 immunotherapy to prevent T cell exhaustion and promote memory without exacerbating toxicity. Science Advances. 9: eadh9879. PMID 38019919 DOI: 10.1126/sciadv.adh9879  0.346
2023 Goldberger Z, Hauert S, Chang K, Kurtanich T, Alpar AT, Repond G, Wang Y, Gomes S, Krishnakumar R, Siddarth P, Swartz MA, Hubbell JA, Briquez PS. Membrane-localized neoantigens predict the efficacy of cancer immunotherapy. Cell Reports. Medicine. 4: 101145. PMID 37552990 DOI: 10.1016/j.xcrm.2023.101145  0.316
2022 Slezak AJ, Mansurov A, Raczy MM, Chang K, Alpar AT, Lauterbach AL, Wallace RP, Weathered RK, Medellin JEG, Battistella C, Gray LT, Marchell TM, Gomes S, Swartz MA, Hubbell JA. Tumor Cell-Surface Binding of Immune Stimulating Polymeric Glyco-Adjuvant via Cysteine-Reactive Pyridyl Disulfide Promotes Antitumor Immunity. Acs Central Science. 8: 1435-1446. PMID 36313164 DOI: 10.1021/acscentsci.2c00704  0.385
2022 Briquez PS, Rouhani SJ, Yu J, Pyzer AR, Trujillo J, Dugan HL, Stamper CT, Changrob S, Sperling AI, Wilson PC, Gajewski TF, Hubbell JA, Swartz MA. Severe COVID-19 induces autoantibodies against angiotensin II that correlate with blood pressure dysregulation and disease severity. Science Advances. 8: eabn3777. PMID 36206332 DOI: 10.1126/sciadv.abn3777  0.319
2022 Mansurov A, Hosseinchi P, Chang K, Lauterbach AL, Gray LT, Alpar AT, Budina E, Slezak AJ, Kang S, Cao S, Solanki A, Gomes S, Williford JM, Swartz MA, Mendoza JL, ... ... Hubbell JA, et al. Masking the immunotoxicity of interleukin-12 by fusing it with a domain of its receptor via a tumour-protease-cleavable linker. Nature Biomedical Engineering. PMID 35534574 DOI: 10.1038/s41551-022-00888-0  0.324
2021 Briquez PS, Rouhani SJ, Yu J, Pyzer AR, Trujillo J, Dugan HL, Stamper CT, Changrob S, Sperling AI, Wilson PC, Gajewski TF, Hubbell JA, Swartz MA. SARS-CoV-2 infection induces cross-reactive autoantibodies against angiotensin II. Medrxiv : the Preprint Server For Health Sciences. PMID 34751272 DOI: 10.1101/2021.11.02.21265789  0.323
2021 Yu SS, Hubbell JA, Swartz MA. Overcoming transport barriers to immunotherapy. Drug Delivery and Translational Research. 11: 2273-2275. PMID 34718959 DOI: 10.1007/s13346-021-01084-4  0.351
2021 Gray LT, Raczy MM, Briquez PS, Marchell TM, Alpar AT, Wallace RP, Volpatti LR, Sasso MS, Cao S, Nguyen M, Mansurov A, Budina E, Watkins EA, Solanki A, Mitrousis N, ... ... Hubbell JA, et al. Generation of potent cellular and humoral immunity against SARS-CoV-2 antigens via conjugation to a polymeric glyco-adjuvant. Biomaterials. 278: 121159. PMID 34634664 DOI: 10.1016/j.biomaterials.2021.121159  0.367
2021 Maulloo CD, Cao S, Watkins EA, Raczy MM, Solanki AS, Nguyen M, Reda JW, Shim HN, Wilson DS, Swartz MA, Hubbell JA. Lymph Node-Targeted Synthetically Glycosylated Antigen Leads to Antigen-Specific Immunological Tolerance. Frontiers in Immunology. 12: 714842. PMID 34630389 DOI: 10.3389/fimmu.2021.714842  0.385
2021 Volpatti LR, Wallace RP, Cao S, Raczy MM, Wang R, Gray LT, Alpar AT, Briquez PS, Mitrousis N, Marchell TM, Sasso MS, Nguyen M, Mansurov A, Budina E, Solanki A, ... ... Hubbell JA, et al. Polymersomes Decorated with the SARS-CoV-2 Spike Protein Receptor-Binding Domain Elicit Robust Humoral and Cellular Immunity. Acs Central Science. 7: 1368-1380. PMID 34466656 DOI: 10.1021/acscentsci.1c00596  0.394
2021 Volpatti LR, Wallace RP, Cao S, Raczy MM, Wang R, Gray LT, Alpar AT, Briquez PS, Mitrousis N, Marchell TM, Sasso MS, Nguyen M, Mansurov A, Budina E, Solanki A, ... ... Hubbell JA, et al. Polymersomes decorated with SARS-CoV-2 spike protein receptor binding domain elicit robust humoral and cellular immunity. Biorxiv : the Preprint Server For Biology. PMID 33851166 DOI: 10.1101/2021.04.08.438884  0.397
2021 Sasso MS, Mitrousis N, Wang Y, Briquez PS, Hauert S, Ishihara J, Hubbell JA, Swartz MA. Lymphangiogenesis-inducing vaccines elicit potent and long-lasting T cell immunity against melanomas. Science Advances. 7. PMID 33762337 DOI: 10.1126/sciadv.abe4362  0.38
2020 Yuba E, Budina E, Katsumata K, Ishihara A, Mansurov A, Alpar AT, Watkins EA, Hosseinchi P, Reda JW, Lauterbach AL, Nguyen M, Solanki A, Kageyama T, Swartz MA, Ishihara J, ... Hubbell JA, et al. Enhanced lymph node trafficking of engineered IL-10 suppresses rheumatoid arthritis in murine models. Arthritis & Rheumatology (Hoboken, N.J.). PMID 33169522 DOI: 10.1002/art.41585  0.304
2020 Ishihara A, Ishihara J, Watkins EA, Tremain AC, Nguyen M, Solanki A, Katsumata K, Mansurov A, Budina E, Alpar AT, Hosseinchi P, Maillat L, Reda JW, Kageyama T, Swartz MA, ... ... Hubbell JA, et al. Prolonged residence of an albumin-IL-4 fusion protein in secondary lymphoid organs ameliorates experimental autoimmune encephalomyelitis. Nature Biomedical Engineering. PMID 33046864 DOI: 10.1038/s41551-020-00627-3  0.342
2020 Mansurov A, Ishihara J, Hosseinchi P, Potin L, Marchell TM, Ishihara A, Williford JM, Alpar AT, Raczy MM, Gray LT, Swartz MA, Hubbell JA. Collagen-binding IL-12 enhances tumour inflammation and drives the complete remission of established immunologically cold mouse tumours. Nature Biomedical Engineering. PMID 32284554 DOI: 10.1038/S41551-020-0549-2  0.399
2020 Briquez PS, Hauert S, de Titta A, Gray LT, Alpar AT, Swartz MA, Hubbell JA. Engineering Targeting Materials for Therapeutic Cancer Vaccines. Frontiers in Bioengineering and Biotechnology. 8: 19. PMID 32117911 DOI: 10.3389/Fbioe.2020.00019  0.418
2020 Gray LT, Wilson DS, Ishihara J, Sasaki K, Raczy M, Swartz M, Hubbell J. Abstract 4582: Tumor matrix-targeted polymeric glyco-adjuvant for in situ cancer vaccination Immunology. 80: 4582-4582. DOI: 10.1158/1538-7445.Am2020-4582  0.442
2019 Williford JM, Ishihara J, Ishihara A, Mansurov A, Hosseinchi P, Marchell TM, Potin L, Swartz MA, Hubbell JA. Recruitment of CD103 dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy. Science Advances. 5: eaay1357. PMID 31844672 DOI: 10.1126/Sciadv.Aay1357  0.45
2019 Mochizuki M, Güç E, Park AJ, Julier Z, Briquez PS, Kuhn GA, Müller R, Swartz MA, Hubbell JA, Martino MM. Growth factors with enhanced syndecan binding generate tonic signalling and promote tissue healing. Nature Biomedical Engineering. PMID 31685999 DOI: 10.1038/S41551-019-0469-1  0.598
2019 Licht C, Rose J, Omidinia Anarkoli A, Blondel D, Roccio M, Haraszti T, Gehlen DB, Hubbell JA, Lutolf MP, De Laporte L. Synthetic 3D PEG-Anisogels tailored with fibronectin fragments induce aligned nerve extension. Biomacromolecules. PMID 31614080 DOI: 10.1021/Acs.Biomac.9B00891  0.582
2019 Wilson DS, Damo M, Hirosue S, Raczy MM, Brünggel K, Diaceri G, Quaglia-Thermes X, Hubbell JA. Synthetically glycosylated antigens induce antigen-specific tolerance and prevent the onset of diabetes. Nature Biomedical Engineering. PMID 31358881 DOI: 10.1038/S41551-019-0424-1  0.301
2019 Ishihara J, Ishihara A, Starke RD, Peghaire CR, Smith KE, McKinnon TA, Tabata Y, Sasaki K, White MJ, Fukunaga K, Laffan MA, Lutolf MP, Randi AM, Hubbell JA. The heparin binding domain of von Willebrand factor binds to growth factors and promotes angiogenesis in wound healing. Blood. PMID 30975637 DOI: 10.1182/Blood.2019000510  0.557
2019 Ishihara J, Ishihara A, Sasaki K, Lee SS, Williford JM, Yasui M, Abe H, Potin L, Hosseinchi P, Fukunaga K, Raczy MM, Gray LT, Mansurov A, Katsumata K, Fukayama M, ... ... Hubbell JA, et al. Targeted antibody and cytokine cancer immunotherapies through collagen affinity. Science Translational Medicine. 11. PMID 30971453 DOI: 10.1126/Scitranslmed.Aau3259  0.427
2019 Vardar E, Vythilingam G, Pinnagoda K, Engelhardt EM, Zambelli PY, Hubbell JA, Lutolf MP, Frey P, Larsson HM. A bioactive injectable bulking material; a potential therapeutic approach for stress urinary incontinence. Biomaterials. 206: 41-48. PMID 30925287 DOI: 10.1016/J.Biomaterials.2019.03.030  0.552
2019 Botelho NK, Tschumi BO, Hubbell JA, Swartz MA, Donda A, Romero P. Combination of Synthetic Long Peptides and XCL1 Fusion Proteins Results in Superior Tumor Control. Frontiers in Immunology. 10: 294. PMID 30863405 DOI: 10.3389/Fimmu.2019.00294  0.466
2019 Hubbell JA, Swartz MA. Trojan horses for immunotherapy. Nature Nanotechnology. PMID 30692676 DOI: 10.1038/S41565-019-0380-7  0.395
2019 Wilson DS, Hirosue S, Raczy MM, Bonilla-Ramirez L, Jeanbart L, Wang R, Kwissa M, Franetich JF, Broggi MAS, Diaceri G, Quaglia-Thermes X, Mazier D, Swartz MA, Hubbell JA. Antigens reversibly conjugated to a polymeric glyco-adjuvant induce protective humoral and cellular immunity. Nature Materials. PMID 30643235 DOI: 10.1038/S41563-018-0256-5  0.457
2019 Ishihara J, Ishihara A, Saskai K, Lee SS, Yasui M, Abe H, Potin L, Hosseinchi P, Fukunaga K, Raczy MM, Gray LT, Williford J, Fukayama M, Marchell TM, Mansurov A, ... ... Hubbell JA, et al. Abstract IA07: Using matrix protein affinity to modulate the tumor microenvironment Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-Ia07  0.444
2019 Sasso MS, Hauert S, Briquez P, Wang Y, Ishihara J, Hubbell JA, Swartz MA. Abstract B130: Induced lymphangiogenesis enhances antigen-specific T-cell response in anticancer vaccination Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-B130  0.319
2019 Sasso MS, Hauert S, Briquez PS, Wang Y, Ishihara J, Hubbell JA, Swartz MA. Abstract 1448: Lymphangiogenesis-inducing whole-cell vaccine against melanoma promotes broad tumor-specific T cell immunity and effective tumor control Cancer Research. 79: 1448-1448. DOI: 10.1158/1538-7445.Am2019-1448  0.307
2018 Ishihara J, Ishihara A, Potin L, Hosseinchi P, Fukunaga K, Damo M, Gajewski TF, Swartz MA, Hubbell JA. Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity. Molecular Cancer Therapeutics. PMID 30097487 DOI: 10.1158/1535-7163.Mct-18-0091  0.447
2018 Ishihara J, Ishihara A, Fukunaga K, Sasaki K, White MJV, Briquez PS, Hubbell JA. Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing. Nature Communications. 9: 2163. PMID 29867149 DOI: 10.1038/S41467-018-04525-W  0.348
2018 Lih E, Kum CH, Park W, Chun SY, Cho Y, Joung YK, Park KS, Hong YJ, Ahn DJ, Kim BS, Kwon TG, Jeong MH, Hubbell JA, Han DK. Modified Magnesium Hydroxide Nanoparticles Inhibits the Inflammatory Response to Biodegradable Poly(lactide-co-glycolide) (PLGA) Implants. Acs Nano. PMID 29812907 DOI: 10.1021/Acsnano.8B02365  0.305
2018 Ishihara J, Ishihara A, Fukunaga K, Potin L, Hosseinchi P, Swartz MA, Hubbell JA. Abstract 959: Extracellular matrix-binding immunotherapies show enhanced antitumor efficacy and reduced adverse events Cancer Research. 78: 959-959. DOI: 10.1158/1538-7445.Am2018-959  0.323
2018 Sevgen E, Dolejsi M, Nealey PF, Hubbell JA, de Pablo JJ. Nanocrystalline Oligo(ethylene sulfide)-b-poly(ethylene glycol) Micelles: Structure and Stability Macromolecules. 51: 9538-9546. DOI: 10.1021/Acs.Macromol.8B01812  0.304
2017 Vardar E, Larsson HM, Allazetta S, Engelhardt EM, Pinnagoda K, Vythilingam G, Hubbell JA, Lutolf MP, Frey P. Microfluidic production of bioactive fibrin micro-beads embedded in crosslinked collagen used as an injectable bulking agent for urinary incontinence treatment. Acta Biomaterialia. 67: 156-166. PMID 29197579 DOI: 10.1016/J.Actbio.2017.11.034  0.592
2017 Ishihara J, Fukunaga K, Ishihara A, Larsson HM, Potin L, Hosseinchi P, Galliverti G, Swartz MA, Hubbell JA. Matrix-binding checkpoint immunotherapies enhance antitumor efficacy and reduce adverse events. Science Translational Medicine. 9. PMID 29118259 DOI: 10.1126/Scitranslmed.Aan0401  0.471
2017 Galan-Navarro C, Rincon-Restrepo M, Zimmer G, Ollmann Saphire E, Hubbell JA, Hirosue S, Swartz MA, Kunz S. Oxidation-sensitive polymersomes as vaccine nanocarriers enhance humoral responses against Lassa virus envelope glycoprotein. Virology. 512: 161-171. PMID 28963882 DOI: 10.1016/J.Virol.2017.09.013  0.428
2017 Baekkeskov S, Hubbell JA, Phelps EA. Bioengineering strategies for inducing tolerance in autoimmune diabetes. Advanced Drug Delivery Reviews. PMID 28625830 DOI: 10.1016/J.Addr.2017.06.007  0.758
2017 Phelps EA, Cianciaruso C, Santo-Domingo J, Pasquier M, Galliverti G, Piemonti L, Berishvili E, Burri O, Wiederkehr A, Hubbell JA, Baekkeskov S. Corrigendum: Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation. Scientific Reports. 7: 46801. PMID 28485397 DOI: 10.1038/srep46801  0.753
2017 Briquez PS, Lorentz KM, Larsson HM, Frey P, Hubbell JA. Human Kunitz-type protease inhibitor engineered for enhanced matrix retention extends longevity of fibrin biomaterials. Biomaterials. 135: 1-9. PMID 28477492 DOI: 10.1016/J.Biomaterials.2017.04.048  0.319
2017 Güç E, Briquez PS, Foretay D, Fankhauser MA, Hubbell JA, Kilarski WW, Swartz MA. Local induction of lymphangiogenesis with engineered fibrin-binding VEGF-C promotes wound healing by increasing immune cell trafficking and matrix remodeling. Biomaterials. 131: 160-175. PMID 28410495 DOI: 10.1016/J.Biomaterials.2017.03.033  0.459
2017 Rincon-Restrepo M, Mayer A, Hauert S, Bonner DK, Phelps EA, Hubbell JA, Swartz MA, Hirosue S. Vaccine nanocarriers: Coupling intracellular pathways and cellular biodistribution to control CD4 vs CD8 T cell responses. Biomaterials. 132: 48-58. PMID 28407494 DOI: 10.1016/J.Biomaterials.2017.03.047  0.716
2017 Phelps EA, Cianciaruso C, Santo-Domingo J, Pasquier M, Galliverti G, Piemonti L, Berishvili E, Burri O, Wiederkehr A, Hubbell JA, Baekkeskov S. Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation. Scientific Reports. 7: 45961. PMID 28401888 DOI: 10.1038/Srep45961  0.776
2017 Dowling DJ, Scott EA, Scheid A, Bergelson I, Joshi S, Pietrasanta C, Brightman S, Sanchez-Schmitz G, Van Haren SD, Ninković J, Kats D, Guiducci C, de Titta A, Bonner DK, Hirosue S, ... ... Hubbell JA, et al. Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses. The Journal of Allergy and Clinical Immunology. PMID 28343701 DOI: 10.1016/J.Jaci.2016.12.985  0.705
2016 Brubaker CE, Panagiotou V, Demurtas D, Bonner DK, Swartz MA, Hubbell JA. A Cationic Micelle Complex Improves CD8+ T Cell Responses in Vaccination Against Unmodified Protein Antigen. Acs Biomaterials Science & Engineering. 2: 231-240. PMID 33418636 DOI: 10.1021/acsbiomaterials.5b00456  0.371
2016 Cianciaruso C, Phelps EA, Pasquier M, Hamelin R, Demurtas D, Ahmed MA, Piemonti L, Hirosue S, Swartz MA, De Palma M, Hubbell JA, Baekkeskov S. Primary Human and Rat Beta Cells Release the Intracellular Autoantigens GAD65, IA-2 and Proinsulin in Exosomes Together with Cytokine-Induced Enhancers of Immunity. Diabetes. PMID 27872147 DOI: 10.2337/Db16-0671  0.785
2016 Lee M, Ahn JI, Ahn JY, Yang WS, Hubbell JA, Lim JM, Lee ST. Difference in suitable mechanical properties of three-dimensional, synthetic scaffolds for self-renewing mouse embryonic stem cells of different genetic backgrounds. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. PMID 27459401 DOI: 10.1002/Jbm.B.33763  0.305
2016 Vardar E, Larsson HM, Engelhardt EM, Pinnagoda K, Briquez PS, Hubbell JA, Frey P. IGF-1-containing multi-layered collagen-fibrin hybrid scaffolds for bladder tissue engineering. Acta Biomaterialia. 41: 75-85. PMID 27286676 DOI: 10.1016/J.Actbio.2016.06.010  0.321
2016 Phelps EA, Cianciaruso C, Michael IP, Pasquier M, Kanaani J, Nano R, Lavallard V, Billestrup N, Hubbell JA, Baekkeskov S. Aberrant accumulation of the diabetes autoantigen GAD65 in Golgi membranes in conditions of ER stress and autoimmunity. Diabetes. PMID 27284108 DOI: 10.2337/Db16-0180  0.765
2016 Julier Z, de Titta A, Grimm AJ, Simeoni E, Swartz MA, Hubbell JA. Fibronectin EDA and CpG synergize to enhance antigen-specific Th1 and cytotoxic responses. Vaccine. PMID 27016652 DOI: 10.1016/J.Vaccine.2016.03.057  0.44
2016 Briquez PS, Clegg LE, Martino MM, Gabhann FM, Hubbell JA. Design principles for therapeutic angiogenic materials Nature Reviews Materials. 1. DOI: 10.1038/Natrevmats.2015.6  0.311
2015 Damo M, Wilson DS, Simeoni E, Hubbell JA. TLR-3 stimulation improves anti-tumor immunity elicited by dendritic cell exosome-based vaccines in a murine model of melanoma. Scientific Reports. 5: 17622. PMID 26631690 DOI: 10.1038/Srep17622  0.311
2015 Lorentz KM, Kontos S, Diaceri G, Henry H, Hubbell JA. Engineered binding to erythrocytes induces immunological tolerance to E. coli asparaginase. Science Advances. 1: e1500112. PMID 26601215 DOI: 10.1126/Sciadv.1500112  0.302
2015 Mitchell AC, Briquez PS, Hubbell JA, Cochran JR. Engineering growth factors for regenerative medicine applications. Acta Biomaterialia. PMID 26555377 DOI: 10.1016/J.Actbio.2015.11.007  0.329
2015 Ballester M, Jeanbart L, de Titta A, Nembrini C, Marsland BJ, Hubbell JA, Swartz MA. Nanoparticle conjugation enhances the immunomodulatory effects of intranasally delivered CpG in house dust mite-allergic mice. Scientific Reports. 5: 14274. PMID 26387548 DOI: 10.1038/Srep14274  0.418
2015 Kontos S, Grimm AJ, Hubbell JA. Engineering antigen-specific immunological tolerance. Current Opinion in Immunology. 35: 80-8. PMID 26163377 DOI: 10.1016/J.Coi.2015.05.005  0.303
2015 Brubaker CE, Velluto D, Demurtas D, Phelps EA, Hubbell JA. Crystalline Oligo(ethylene sulfide) Domains Define Highly Stable Supramolecular Block Copolymer Assemblies. Acs Nano. 9: 6872-81. PMID 26125494 DOI: 10.1021/Acsnano.5B02937  0.689
2015 Vardar E, Engelhardt EM, Larsson HM, Mouloungui E, Pinnagoda K, Hubbell JA, Frey P. Tubular Compressed Collagen Scaffolds for Ureteral Tissue Engineering in a Flow Bioreactor System. Tissue Engineering. Part A. 21: 2334-45. PMID 26065873 DOI: 10.1089/Ten.Tea.2015.0048  0.313
2015 Jeanbart L, Kourtis IC, van der Vlies AJ, Swartz MA, Hubbell JA. 6-Thioguanine-loaded polymeric micelles deplete myeloid-derived suppressor cells and enhance the efficacy of T cell immunotherapy in tumor-bearing mice. Cancer Immunology, Immunotherapy : Cii. 64: 1033-46. PMID 25982370 DOI: 10.1007/S00262-015-1702-8  0.476
2015 Martino MM, Brkic S, Bovo E, Burger M, Schaefer DJ, Wolff T, Gürke L, Briquez PS, Larsson HM, Gianni-Barrera R, Hubbell JA, Banfi A. Extracellular matrix and growth factor engineering for controlled angiogenesis in regenerative medicine. Frontiers in Bioengineering and Biotechnology. 3: 45. PMID 25883933 DOI: 10.3389/Fbioe.2015.00045  0.306
2015 Julier Z, Martino MM, de Titta A, Jeanbart L, Hubbell JA. The TLR4 agonist fibronectin extra domain A is cryptic, exposed by elastase-2; use in a fibrin matrix cancer vaccine. Scientific Reports. 5: 8569. PMID 25708982 DOI: 10.1038/Srep08569  0.313
2015 Ferreira DS, Lin YA, Cui H, Hubbell JA, Reis RL, Azevedo HS. Molecularly engineered self-assembling membranes for cell-mediated degradation. Advanced Healthcare Materials. 4: 602-12. PMID 25413155 DOI: 10.1002/Adhm.201400586  0.303
2015 Ahn JI, Kim GA, Kwon HS, Ahn JY, Hubbell JA, Song YS, Lee ST, Lim JM. Culture of preantral follicles in poly(ethylene) glycol-based, three-dimensional hydrogel: a relationship between swelling ratio and follicular developments. Journal of Tissue Engineering and Regenerative Medicine. 9: 319-23. PMID 24493269 DOI: 10.1002/Term.1824  0.346
2015 Ihm JE, Lee ST, Han DK, Lim JM, Hubbell JA. Murine ovarian follicle culture in PEG-Hydrogel: Effects of mechanical properties and the hormones FSH and LH on development Macromolecular Research. DOI: 10.1007/S13233-015-3045-X  0.31
2015 Jeanbart L, Kourtis IC, van der Vlies AJ, Swartz MA, Hubbell JA. 6-Thioguanine-loaded polymeric micelles deplete myeloid-derived suppressor cells and enhance the efficacy of T cell immunotherapy in tumor-bearing mice Cancer Immunology, Immunotherapy. DOI: 10.1007/s00262-015-1702-8  0.376
2014 Zakrzewski JL, van den Brink MR, Hubbell JA. Overcoming immunological barriers in regenerative medicine. Nature Biotechnology. 32: 786-94. PMID 25093888 DOI: 10.1038/Nbt.2960  0.305
2014 Vila OF, Martino MM, Nebuloni L, Kuhn G, Pérez-Amodio S, Müller R, Hubbell JA, Rubio N, Blanco J. Bioluminescent and micro-computed tomography imaging of bone repair induced by fibrin-binding growth factors. Acta Biomaterialia. 10: 4377-89. PMID 24905933 DOI: 10.1016/J.Actbio.2014.05.028  0.541
2014 Jeanbart L, Ballester M, de Titta A, Corthésy P, Romero P, Hubbell JA, Swartz MA. Enhancing efficacy of anticancer vaccines by targeted delivery to tumor-draining lymph nodes Cancer Immunology Research. 2: 436-447. PMID 24795356 DOI: 10.1158/2326-6066.Cir-14-0019-T  0.439
2014 Sacchi V, Mittermayr R, Hartinger J, Martino MM, Lorentz KM, Wolbank S, Hofmann A, Largo RA, Marschall JS, Groppa E, Gianni-Barrera R, Ehrbar M, Hubbell JA, Redl H, Banfi A. Long-lasting fibrin matrices ensure stable and functional angiogenesis by highly tunable, sustained delivery of recombinant VEGF164. Proceedings of the National Academy of Sciences of the United States of America. 111: 6952-7. PMID 24778233 DOI: 10.1073/Pnas.1404605111  0.31
2014 Martino MM, Briquez PS, Güç E, Tortelli F, Kilarski WW, Metzger S, Rice JJ, Kuhn GA, Müller R, Swartz MA, Hubbell JA. Growth factors engineered for super-affinity to the extracellular matrix enhance tissue healing. Science (New York, N.Y.). 343: 885-8. PMID 24558160 DOI: 10.1126/Science.1247663  0.614
2014 Thomas SN, Vokali E, Lund AW, Hubbell JA, Swartz MA. Targeting the tumor-draining lymph node with adjuvanted nanoparticles reshapes the anti-tumor immune response Biomaterials. 35: 814-824. PMID 24144906 DOI: 10.1016/J.Biomaterials.2013.10.003  0.437
2014 Vasdekis AE, Scott EA, Hubbell JA, Saltis D. Vesicle photonics in biology with a focus on single cell analysis 2014 Ieee Photonics Conference, Ipc 2014. 3-4. DOI: 10.1109/IPCon.2014.6994960  0.646
2014 Vasdekis AE, Scott EA, O'Neil CP, Psaltis D, Hubbell JA. Cytoplasmic Stopped Flow at the Single Cell Level Based on Photosensitive Polymersomes Biophysical Journal. 106: 420. DOI: 10.1016/J.Bpj.2013.11.2365  0.696
2014 Rice JJ, Martino MM, Scott EA, Hubbell JA. Controlled Release Strategies in Tissue Engineering Tissue Engineering: Second Edition. 347-392. DOI: 10.1016/B978-0-12-420145-3.00011-0  0.693
2014 Lee CY, Teymour F, Camastral H, Tirelli N, Hubbell JA, Elbert DL, Papavasiliou G. Characterization of the Network Structure of PEG Diacrylate Hydrogels Formed in the Presence of N-Vinyl Pyrrolidone Macromolecular Reaction Engineering. 8: 314-328. DOI: 10.1002/Mren.201300166  0.779
2013 De Titta A, Ballester M, Julier Z, Nembrini C, Jeanbart L, Van Der Vlies AJ, Swartz MA, Hubbell JA. Nanoparticle conjugation of CpG enhances adjuvancy for cellular immunity and memory recall at low dose Proceedings of the National Academy of Sciences of the United States of America. 110: 19902-19907. PMID 24248387 DOI: 10.1073/Pnas.1313152110  0.454
2013 Tortelli F, Pisano M, Briquez PS, Martino MM, Hubbell JA. Fibronectin Binding Modulates CXCL11 Activity and Facilitates Wound Healing Plos One. 8. PMID 24205388 DOI: 10.1371/Journal.Pone.0079610  0.318
2013 Mosiewicz KA, Kolb L, Van Der Vlies AJ, Martino MM, Lienemann PS, Hubbell JA, Ehrbar M, Lutolf MP. In situ cell manipulation through enzymatic hydrogel photopatterning Nature Materials. 12: 1072-1078. PMID 24121990 DOI: 10.1038/Nmat3766  0.607
2013 Rutkowski JM, Ihm JE, Lee ST, Kilarski WW, Greenwood VI, Pasquier MC, Quazzola A, Trono D, Hubbell JA, Swartz MA. VEGFR-3 neutralization inhibits ovarian lymphangiogenesis, follicle maturation, and murine pregnancy. The American Journal of Pathology. 183: 1596-607. PMID 24036251 DOI: 10.1016/J.Ajpath.2013.07.031  0.419
2013 Hasegawa U, Van Der Vlies AJ, Wandrey C, Hubbell JA. Preparation of well-defined ibuprofen prodrug micelles by RAFT polymerization Biomacromolecules. 14: 3314-3320. PMID 23937521 DOI: 10.1021/Bm4009149  0.315
2013 Brady AC, Martino MM, Pedraza E, Sukert S, Pileggi A, Ricordi C, Hubbell JA, Stabler CL. Proangiogenic hydrogels within macroporous scaffolds enhance islet engraftment in an extrahepatic site Tissue Engineering - Part A. 19: 2544-2552. PMID 23790218 DOI: 10.1089/Ten.Tea.2012.0686  0.313
2013 Traub S, Morgner J, Martino MM, Höning S, Swartz MA, Wickström SA, Hubbell JA, Eming SA. The promotion of endothelial cell attachment and spreading using FNIII10 fused to VEGF-A165 Biomaterials. 34: 5958-5968. PMID 23683723 DOI: 10.1016/J.Biomaterials.2013.04.050  0.451
2013 Hoffmann DC, Willenborg S, Koch M, Zwolanek D, Müller S, Becker AK, Metzger S, Ehrbar M, Kurschat P, Hellmich M, Hubbell JA, Eming SA. Proteolytic processing regulates placental growth factor activities. The Journal of Biological Chemistry. 288: 17976-89. PMID 23645683 DOI: 10.1074/Jbc.M113.451831  0.306
2013 Kourtis IC, Hirosue S, de Titta A, Kontos S, Stegmann T, Hubbell JA, Swartz MA. Peripherally Administered Nanoparticles Target Monocytic Myeloid Cells, Secondary Lymphoid Organs and Tumors in Mice Plos One. 8. PMID 23626707 DOI: 10.1371/Journal.Pone.0061646  0.477
2013 Martino MM, Briquez PS, Ranga A, Lutolf MP, Hubbell JA. Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix Proceedings of the National Academy of Sciences of the United States of America. 110: 4563-4568. PMID 23487783 DOI: 10.1073/Pnas.1221602110  0.556
2013 Stano A, Scott EA, Dane KY, Swartz MA, Hubbell JA. Tunable T cell immunity towards a protein antigen using polymersomes vs. solid-core nanoparticles Biomaterials. 34: 4339-4346. PMID 23478034 DOI: 10.1016/J.Biomaterials.2013.02.024  0.724
2013 Kontos S, Kourtis IC, Dane KY, Hubbell JA. Engineering antigens for in situ erythrocyte binding induces T-cell deletion Proceedings of the National Academy of Sciences of the United States of America. 110: E60-E68. PMID 23248266 DOI: 10.1073/Pnas.1216353110  0.329
2013 Rice JJ, Martino MM, De Laporte L, Tortelli F, Briquez PS, Hubbell JA. Engineering the Regenerative Microenvironment with Biomaterials Advanced Healthcare Materials. 2: 57-71. PMID 23184739 DOI: 10.1002/Adhm.201200197  0.343
2013 Kisiel M, Martino MM, Ventura M, Hubbell JA, Hilborn J, Ossipov DA. Improving the osteogenic potential of BMP-2 with hyaluronic acid hydrogel modified with integrin-specific fibronectin fragment. Biomaterials. 34: 704-12. PMID 23103154 DOI: 10.1016/J.Biomaterials.2012.10.015  0.338
2013 Vasdekis AE, Scott EA, O'Neil CP, Psaltis D, Hubbell JA. Optical manipulation of vesicles for optofluidic applications Proceedings of Spie - the International Society For Optical Engineering. 8810. DOI: 10.1117/12.2026583  0.67
2013 Hopkins AM, De Laporte L, Tortelli F, Spedden E, Staii C, Atherton TJ, Hubbell JA, Kaplan DL. Silk hydrogels as soft substrates for neural tissue engineering Advanced Functional Materials. 23: 5140-5149. DOI: 10.1002/Adfm.201300435  0.329
2012 Larsson HM, Lee ST, Roccio M, Velluto D, Lutolf MP, Frey P, Hubbell JA. Sorting live stem cells based on Sox2 mRNA expression. Plos One. 7: e49874. PMID 23209609 DOI: 10.1371/Journal.Pone.0049874  0.563
2012 Stano A, Nembrini C, Swartz MA, Hubbell JA, Simeoni E. Nanoparticle size influences the magnitude and quality of mucosal immune responses after intranasal immunization Vaccine. 30: 7541-7546. PMID 23103199 DOI: 10.1016/J.Vaccine.2012.10.050  0.446
2012 Lee ST, Yun JI, van der Vlies AJ, Kontos S, Jang M, Gong SP, Kim DY, Lim JM, Hubbell JA. Long-term maintenance of mouse embryonic stem cell pluripotency by manipulating integrin signaling within 3D scaffolds without active Stat3. Biomaterials. 33: 8934-42. PMID 22998814 DOI: 10.1016/J.Biomaterials.2012.08.062  0.302
2012 Van Der Vlies AJ, Hasegawa U, Hubbell JA. Reduction-sensitive tioguanine prodrug micelles Molecular Pharmaceutics. 9: 2812-2818. PMID 22954101 DOI: 10.1021/Mp3001183  0.36
2012 Swartz MA, Hirosue S, Hubbell JA. Engineering approaches to immunotherapy Science Translational Medicine. 4. PMID 22914624 DOI: 10.1126/Scitranslmed.3003763  0.459
2012 Vasdekis AE, Scott EA, O'Neil CP, Psaltis D, Hubbell JA. Precision intracellular delivery based on optofluidic polymersome rupture. Acs Nano. 6: 7850-7. PMID 22900579 DOI: 10.1021/Nn302122H  0.717
2012 Micol LA, Arenas da Silva LF, Geutjes PJ, Oosterwijk E, Hubbell JA, Feitz WFJ, Frey P. In-vivo performance of high-density collagen gel tubes for urethral regeneration in a rabbit model Biomaterials. 33: 7447-7455. PMID 22795859 DOI: 10.1016/J.Biomaterials.2012.06.087  0.301
2012 Eby JK, Dane KY, O'Neil CP, Hirosue S, Swartz MA, Hubbell JA. Polymer micelles with pyridyl disulfide-coupled antigen travel through lymphatics and show enhanced cellular responses following immunization Acta Biomaterialia. 8: 3210-3217. PMID 22698945 DOI: 10.1016/J.Actbio.2012.06.007  0.484
2012 Scott EA, Stano A, Gillard M, Maio-Liu AC, Swartz MA, Hubbell JA. Dendritic cell activation and T cell priming with adjuvant- and antigen-loaded oxidation-sensitive polymersomes Biomaterials. 33: 6211-6219. PMID 22658634 DOI: 10.1016/J.Biomaterials.2012.04.060  0.739
2012 Lorentz KM, Yang L, Frey P, Hubbell JA. Engineered insulin-like growth factor-1 for improved smooth muscle regeneration Biomaterials. 33: 494-503. PMID 22014943 DOI: 10.1016/J.Biomaterials.2011.09.088  0.319
2011 Nembrini C, Stano A, Dane KY, Ballester M, Van Der Vlies AJ, Marsland BJ, Swartz MA, Hubbell JA. Nanoparticle conjugation of antigen enhances cytotoxic T-cell responses in pulmonary vaccination Proceedings of the National Academy of Sciences of the United States of America. 108: E989-E997. PMID 21969597 DOI: 10.1073/Pnas.1104264108  0.458
2011 Velluto D, Thomas SN, Simeoni E, Swartz MA, Hubbell JA. PEG-b-PPS-b-PEI micelles and PEG-b-PPS/PEG-b-PPS-b-PEI mixed micelles as non-viral vectors for plasmid DNA: Tumor immunotoxicity in B16F10 melanoma Biomaterials. 32: 9839-9847. PMID 21924769 DOI: 10.1016/J.Biomaterials.2011.08.079  0.437
2011 Martino MM, Tortelli F, Mochizuki M, Traub S, Ben-David D, Kuhn GA, Müller R, Livne E, Eming SA, Hubbell JA. Engineering the growth factor microenvironment with fibronectin domains to promote wound and bone tissue healing. Science Translational Medicine. 3: 100ra89. PMID 21918106 DOI: 10.1126/Scitranslmed.3002614  0.531
2011 Dane KY, Nembrini C, Tomei AA, Eby JK, O'Neil CP, Velluto D, Swartz MA, Inverardi L, Hubbell JA. Nano-sized drug-loaded micelles deliver payload to lymph node immune cells and prolong allograft survival Journal of Controlled Release. 156: 154-160. PMID 21864593 DOI: 10.1016/J.Jconrel.2011.08.009  0.449
2011 Ballester M, Nembrini C, Dhar N, de Titta A, de Piano C, Pasquier M, Simeoni E, van der Vlies AJ, McKinney JD, Hubbell JA, Swartz MA. Nanoparticle conjugation and pulmonary delivery enhance the protective efficacy of Ag85B and CpG against tuberculosis Vaccine. 29: 6959-6966. PMID 21787826 DOI: 10.1016/J.Vaccine.2011.07.039  0.433
2011 Engelhardt EM, Micol LA, Houis S, Wurm FM, Hilborn J, Hubbell JA, Frey P. A collagen-poly(lactic acid-co-É›-caprolactone) hybrid scaffold for bladder tissue regeneration. Biomaterials. 32: 3969-76. PMID 21377203 DOI: 10.1016/J.Biomaterials.2011.02.012  0.38
2011 Yu SS, Scherer RL, Ortega RA, Bell CS, O'Neil CP, Hubbell JA, Giorgio TD. Enzymatic- and temperature-sensitive controlled release of ultrasmall superparamagnetic iron oxides (USPIOs) Journal of Nanobiotechnology. 9. PMID 21352596 DOI: 10.1186/1477-3155-9-7  0.325
2011 Thomas SN, van der Vlies AJ, O'Neil CP, Reddy ST, Yu SS, Giorgio TD, Swartz MA, Hubbell JA. Engineering complement activation on polypropylene sulfide vaccine nanoparticles Biomaterials. 32: 2194-2203. PMID 21183216 DOI: 10.1016/J.Biomaterials.2010.11.037  0.46
2011 Wandrey C, Hasegawa U, van der Vlies AJ, O'Neil C, Angelova N, Hubbell JA. Analytical ultracentrifugation to support the development of biomaterials and biomedical devices Methods. 54: 92-100. PMID 21146611 DOI: 10.1016/J.Ymeth.2010.12.003  0.308
2011 Stano A, van der Vlies AJ, Martino MM, Swartz MA, Hubbell JA, Simeoni E. PPS nanoparticles as versatile delivery system to induce systemic and broad mucosal immunity after intranasal administration Vaccine. 29: 804-812. PMID 21094269 DOI: 10.1016/J.Vaccine.2010.11.010  0.469
2011 Micol LA, Ananta M, Engelhardt EM, Mudera VC, Brown RA, Hubbell JA, Frey P. High-density collagen gel tubes as a matrix for primary human bladder smooth muscle cells. Biomaterials. 32: 1543-8. PMID 21074843 DOI: 10.1016/J.Biomaterials.2010.10.028  0.335
2011 Patterson J, Hubbell JA. SPARC-derived protease substrates to enhance the plasmin sensitivity of molecularly engineered PEG hydrogels Biomaterials. 32: 1301-1310. PMID 21040970 DOI: 10.1016/J.Biomaterials.2010.10.016  0.357
2011 Kraehenbuehl TP, Ferreira LS, Hayward AM, Nahrendorf M, van der Vlies AJ, Vasile E, Weissleder R, Langer R, Hubbell JA. Human embryonic stem cell-derived microvascular grafts for cardiac tissue preservation after myocardial infarction Biomaterials. 32: 1102-1109. PMID 21035182 DOI: 10.1016/J.Biomaterials.2010.10.005  0.321
2011 Lorentz KM, Kontos S, Frey P, Hubbell JA. Engineered aprotinin for improved stability of fibrin biomaterials Biomaterials. 32: 430-438. PMID 20864171 DOI: 10.1016/J.Biomaterials.2010.08.109  0.332
2010 Hasegawa U, Van Der Vlies AJ, Simeoni E, Wandrey C, Hubbell JA. Carbon monoxide-releasing micelles for immunotherapy Journal of the American Chemical Society. 132: 18273-18280. PMID 21128648 DOI: 10.1021/Ja1075025  0.333
2010 Hirosue S, Kourtis IC, van der Vlies AJ, Hubbell JA, Swartz MA. Antigen delivery to dendritic cells by poly(propylene sulfide) nanoparticles with disulfide conjugated peptides: Cross-presentation and T cell activation Vaccine. 28: 7897-7906. PMID 20934457 DOI: 10.1016/J.Vaccine.2010.09.077  0.488
2010 Popa AM, Angeloni S, Bürgi T, Hubbell JA, Heinzelmann H, Pugin R. Dynamic perspective on the function of thermoresponsive nanopores from in situ AFM and ATR-IR investigations. Langmuir : the Acs Journal of Surfaces and Colloids. 26: 15356-65. PMID 20822117 DOI: 10.1021/La102611K  0.303
2010 Bott K, Upton Z, Schrobback K, Ehrbar M, Hubbell JA, Lutolf MP, Rizzi SC. The effect of matrix characteristics on fibroblast proliferation in 3D gels. Biomaterials. 31: 8454-64. PMID 20684983 DOI: 10.1016/J.Biomaterials.2010.07.046  0.587
2010 Patterson J, Hubbell JA. Enhanced proteolytic degradation of molecularly engineered PEG hydrogels in response to MMP-1 and MMP-2. Biomaterials. 31: 7836-45. PMID 20667588 DOI: 10.1016/J.Biomaterials.2010.06.061  0.349
2010 Missirlis D, Hubbell JA. In vitro uptake of amphiphilic, hydrogel nanoparticles by J774A.1 cells. Journal of Biomedical Materials Research. Part A. 93: 1557-65. PMID 20014289 DOI: 10.1002/Jbm.A.32648  0.326
2010 Lavanant L, Pullin B, Hubbell JA, Klok HA. A facile strategy for the modification of polyethylene substrates with non-fouling, bioactive poly(poly(ethylene glycol) methacrylate) brushes. Macromolecular Bioscience. 10: 101-8. PMID 19890949 DOI: 10.1002/Mabi.200900205  0.358
2010 Engelhardt EM, Stegberg E, Brown RA, Hubbell JA, Wurm FM, Adam M, Frey P. Compressed collagen gel: a novel scaffold for human bladder cells. Journal of Tissue Engineering and Regenerative Medicine. 4: 123-30. PMID 19842107 DOI: 10.1002/Term.222  0.356
2010 Jo YS, Rizzi SC, Ehrbar M, Weber FE, Hubbell JA, Lutolf MP. Biomimetic PEG hydrogels crosslinked with minimal plasmin-sensitive tri-amino acid peptides. Journal of Biomedical Materials Research. Part A. 93: 870-7. PMID 19701911 DOI: 10.1002/Jbm.A.32580  0.585
2010 Di Meo EM, Di Crescenzo A, Velluto D, O'Neil CP, Demurtas D, Hubbell JA, Fontana A. Assessing the role of polyethylene glycol-bl-propylene sulfide (PEG-PPS) block copolymers in the preparation of carbon nanotube biocompatible dispersions Macromolecules. 43: 3429-3437. DOI: 10.1021/Ma902443J  0.303
2010 Patterson J, Martino MM, Hubbell JA. Biomimetic materials in tissue engineering Materials Today. 13: 14-22. DOI: 10.1016/S1369-7021(10)70013-4  0.327
2009 Hubbell JA, Thomas SN, Swartz MA. Materials engineering for immunomodulation. Nature. 462: 449-60. PMID 19940915 DOI: 10.1038/Nature08604  0.473
2009 Cerritelli S, O'Neil CP, Velluto D, Fontana A, Adrian M, Dubochet J, Hubbell JA. Aggregation behavior of poly(ethylene glycol-bl-propylene sulfide) di- and triblock copolymers in aqueous solution. Langmuir : the Acs Journal of Surfaces and Colloids. 25: 11328-35. PMID 19711914 DOI: 10.1021/La900649M  0.319
2009 O'Neil CP, Suzuki T, Demurtas D, Finka A, Hubbell JA. A novel method for the encapsulation of biomolecules into polymersomes via direct hydration. Langmuir : the Acs Journal of Surfaces and Colloids. 25: 9025-9. PMID 19621886 DOI: 10.1021/La900779T  0.338
2009 Kraehenbuehl TP, Ferreira LS, Zammaretti P, Hubbell JA, Langer R. Cell-responsive hydrogel for encapsulation of vascular cells. Biomaterials. 30: 4318-24. PMID 19500842 DOI: 10.1016/J.Biomaterials.2009.04.057  0.35
2009 O'Neil CP, van der Vlies AJ, Velluto D, Wandrey C, Demurtas D, Dubochet J, Hubbell JA. Extracellular matrix binding mixed micelles for drug delivery applications. Journal of Controlled Release : Official Journal of the Controlled Release Society. 137: 146-51. PMID 19332089 DOI: 10.1016/J.Jconrel.2009.03.013  0.341
2009 Martino MM, Mochizuki M, Rothenfluh DA, Rempel SA, Hubbell JA, Barker TH. Controlling integrin specificity and stem cell differentiation in 2D and 3D environments through regulation of fibronectin domain stability. Biomaterials. 30: 1089-97. PMID 19027948 DOI: 10.1016/J.Biomaterials.2008.10.047  0.323
2009 Drumheller PD, Elbert DL, Hubbell JA. Multifunctional poly(ethylene glycol) semi-interpenetrating polymer networks as highly selective adhesive substrates for bioadhesive peptide grafting. Biotechnology and Bioengineering. 43: 772-80. PMID 18615801 DOI: 10.1002/Bit.260430812  0.786
2009 Jo YS, Gantz J, Hubbell JA, Lutolf MP. Tailoring hydrogel degradation and drug release via neighboring amino acid controlled ester hydrolysis Soft Matter. 5: 440-446. DOI: 10.1039/B814584A  0.58
2008 Velluto D, Demurtas D, Hubbell JA. PEG-b-PPS diblock copolymer aggregates for hydrophobic drug solubilization and release: Cyclosporin A as an example Molecular Pharmaceutics. 5: 632-642. PMID 18547055 DOI: 10.1021/Mp7001297  0.31
2008 Kraehenbuehl TP, Zammaretti P, Van der Vlies AJ, Schoenmakers RG, Lutolf MP, Jaconi ME, Hubbell JA. Three-dimensional extracellular matrix-directed cardioprogenitor differentiation: Systematic modulation of a synthetic cell-responsive PEG-hydrogel Biomaterials. 29: 2757-2766. PMID 18396331 DOI: 10.1016/J.Biomaterials.2008.03.016  0.58
2008 Rothenfluh DA, Bermudez H, O'Neil CP, Hubbell JA. Biofunctional polymer nanoparticles for intra-articular targeting and retention in cartilage. Nature Materials. 7: 248-54. PMID 18246072 DOI: 10.1038/Nmat2116  0.335
2008 Rehor A, Schmoekel H, Tirelli N, Hubbell JA. Functionalization of polysulfide nanoparticles and their performance as circulating carriers Biomaterials. 29: 1958-1966. PMID 18242691 DOI: 10.1016/J.Biomaterials.2007.12.035  0.56
2008 Swartz MA, Hubbell JA, Reddy ST. Lymphatic drainage function and its immunological implications: From dendritic cell homing to vaccine design Seminars in Immunology. 20: 147-156. PMID 18201895 DOI: 10.1016/J.Smim.2007.11.007  0.452
2008 Adelöw C, Segura T, Hubbell JA, Frey P. The effect of enzymatically degradable poly(ethylene glycol) hydrogels on smooth muscle cell phenotype. Biomaterials. 29: 314-26. PMID 17953986 DOI: 10.1016/J.Biomaterials.2007.09.036  0.577
2008 Raeber GP, Lutolf MP, Hubbell JA. Part II: Fibroblasts preferentially migrate in the direction of principal strain Biomechanics and Modeling in Mechanobiology. 7: 215-225. PMID 17619206 DOI: 10.1007/S10237-007-0090-1  0.545
2008 Raeber GP, Mayer J, Hubbell JA. Part I: A novel in-vitro system for simultaneous mechanical stimulation and time-lapse microscopy in 3D Biomechanics and Modeling in Mechanobiology. 7: 203-214. PMID 17487518 DOI: 10.1007/S10237-007-0086-X  0.312
2008 Feller L, Bearinger JP, Wu L, Hubbell JA, Textor M, Tosatti S. Micropatterning of gold substrates based on poly(propylene sulfide-bl-ethylene glycol), (PPS-PEG) background passivation and the molecular-assembly patterning by lift-off (MAPL) technique Surface Science. 602: 2305-2310. DOI: 10.1016/J.Susc.2008.05.010  0.306
2008 Ehrbar M, Lütolf MP, Rizzi SC, Hubbell JA, Weber FE. Artificial extracellular matrices for bone tissue engineering Bone. 42: S72. DOI: 10.1016/J.Bone.2007.12.131  0.526
2008 Hubbell J. Chapter 15 – Controlled release strategies in tissue engineering Tissue Engineering. 455-482. DOI: 10.1016/B978-0-12-370869-4.00015-X  0.326
2007 Ehrbar M, Rizzi SC, Schoenmakers RG, Miguel BS, Hubbell JA, Weber FE, Lutolf MP. Biomolecular hydrogels formed and degraded via site-specific enzymatic reactions. Biomacromolecules. 8: 3000-7. PMID 17883273 DOI: 10.1021/Bm070228F  0.619
2007 Reddy ST, van der Vlies AJ, Simeoni E, Angeli V, Randolph GJ, O'Neil CP, Lee LK, Swartz MA, Hubbell JA. Exploiting lymphatic transport and complement activation in nanoparticle vaccines. Nature Biotechnology. 25: 1159-64. PMID 17873867 DOI: 10.1038/Nbt1332  0.452
2007 Raeber GP, Lutolf MP, Hubbell JA. Mechanisms of 3-D migration and matrix remodeling of fibroblasts within artificial ECMs Acta Biomaterialia. 3: 615-629. PMID 17572164 DOI: 10.1016/J.Actbio.2007.03.013  0.581
2007 Ehrbar M, Rizzi SC, Hlushchuk R, Djonov V, Zisch AH, Hubbell JA, Weber FE, Lutolf MP. Enzymatic formation of modular cell-instructive fibrin analogs for tissue engineering Biomaterials. 28: 3856-3866. PMID 17568666 DOI: 10.1016/J.Biomaterials.2007.03.027  0.614
2007 Segura T, Schmokel H, Hubbell JA. RNA interference targeting hypoxia inducible factor 1alpha reduces post-operative adhesions in rats. The Journal of Surgical Research. 141: 162-70. PMID 17561118 DOI: 10.1016/J.Jss.2006.07.045  0.525
2007 Cerritelli S, Velluto D, Hubbell JA. PEG-SS-PPS: Reduction-sensitive disulfide block copolymer vesicles for intracellular drug delivery Biomacromolecules. 8: 1966-1972. PMID 17497921 DOI: 10.1021/Bm070085X  0.351
2007 Segura T, Hubbell JA. Synthesis and in vitro characterization of an ABC triblock copolymer for siRNA delivery. Bioconjugate Chemistry. 18: 736-45. PMID 17358044 DOI: 10.1021/Bc060284Y  0.575
2007 Román I, Vilalta M, Rodriguez J, Matthies AM, Srouji S, Livne E, Hubbell JA, Rubio N, Blanco J. Analysis of progenitor cell-scaffold combinations by in vivo non-invasive photonic imaging Biomaterials. 28: 2718-2728. PMID 17346789 DOI: 10.1016/J.Biomaterials.2007.02.011  0.319
2007 Reddy ST, van der Vlies AJ, Simeoni E, O'Neil CP, Swartz MA, Hubbell JA. Exploiting lymphatic transport and complement activation in nanoparticle vaccines European Cells and Materials. 14: 103. DOI: 10.1038/nbt1332  0.315
2007 Frey P, Segura T, Adelöw C, Hubbell J. Bladder smooth muscle cell differentiation and induction of mesenchymal stem cell differentiation in a three dimensional hydrogel matrix Journal of Pediatric Urology. 3: S55. DOI: 10.1016/J.Jpurol.2007.01.092  0.556
2007 Ihm J, Rutkowski J, Lee S, Hubbell J, Swartz M. Lymphangiogenesis in the ovary: importance in follicle maturation and murine pregnancy Fertility and Sterility. 88: S73. DOI: 10.1016/J.Fertnstert.2007.07.244  0.371
2006 Rizzi SC, Ehrbar M, Halstenberg S, Raeber GP, Schmoekel HG, Hagenmüller H, Müller R, Weber FE, Hubbell JA. Recombinant protein-co-PEG networks as cell-adhesive and proteolytically degradable hydrogel matrixes. Part II: biofunctional characteristics. Biomacromolecules. 7: 3019-29. PMID 17096527 DOI: 10.1021/Bm060504A  0.389
2006 Reddy ST, Swartz MA, Hubbell JA. Targeting dendritic cells with biomaterials: developing the next generation of vaccines. Trends in Immunology. 27: 573-9. PMID 17049307 DOI: 10.1016/J.It.2006.10.005  0.449
2006 Billinger M, Buddeberg F, Hubbell JA, Elbert DL, Schaffner T, Mettler D, Windecker S, Meier B, Hess OM. Polymer stent coating for prevention of neointimal hyperplasia. The Journal of Invasive Cardiology. 18: 423-6; discussion 42. PMID 16954581  0.755
2006 Missirlis D, Kawamura R, Tirelli N, Hubbell JA. Doxorubicin encapsulation and diffusional release from stable, polymeric, hydrogel nanoparticles. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 29: 120-9. PMID 16904301 DOI: 10.1016/J.Ejps.2006.06.003  0.574
2006 Reddy ST, Rehor A, Schmoekel HG, Hubbell JA, Swartz MA. In vivo targeting of dendritic cells in lymph nodes with poly(propylene sulfide) nanoparticles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 112: 26-34. PMID 16529839 DOI: 10.1016/J.Jconrel.2006.01.006  0.438
2006 Rizzi SC, Hubbell JA. Recombinant protein-co-PEG networks as cell-adhesive and proteolytically degradable hydrogel matrixes. Part I: Development and physicochemical characteristics. Biomacromolecules. 6: 1226-38. PMID 15877337 DOI: 10.1021/Bm049614C  0.384
2006 Missirlis D, Hubbell JA, Tirelli N. Thermally-induced glass formation from hydrogel nanoparticles Soft Matter. 2: 1067. DOI: 10.1039/B607437E  0.554
2006 Adelöw C, Segura T, Hubbell J, Frey P. A three dimensional matrix for guided mesenchymal stem cell and urothelial cell growth and differentiation Journal of Biomechanics. 39: S578. DOI: 10.1016/S0021-9290(06)85390-X  0.494
2006 Hubbell J, Segura T, Adelöw C, Kraehenbuehl T, Martino M, Frey P, Barker T. Three-dimensional scaffolds in tissue engineering Journal of Biomechanics. 39: S258. DOI: 10.1016/S0021-9290(06)83984-9  0.472
2005 Maynard HD, Hubbell JA. Discovery of a sulfated tetrapeptide that binds to vascular endothelial growth factor. Acta Biomaterialia. 1: 451-9. PMID 16701826 DOI: 10.1016/J.Actbio.2005.04.004  0.561
2005 Napoli A, Bermudez H, Hubbell JA. Interfacial reactivity of block copolymers: understanding the amphiphile-to-hydrophile transition. Langmuir : the Acs Journal of Surfaces and Colloids. 21: 9149-53. PMID 16171345 DOI: 10.1021/La0512300  0.324
2005 Thurner PJ, Müller R, Raeber G, Sennhauser U, Hubbell JA. 3D morphology of cell cultures: a quantitative approach using micrometer synchrotron light tomography. Microscopy Research and Technique. 66: 289-298. PMID 16003782 DOI: 10.1002/Jemt.20170  0.354
2005 Raeber GP, Lutolf MP, Hubbell JA. Molecularly engineered PEG hydrogels: a novel model system for proteolytically mediated cell migration. Biophysical Journal. 89: 1374-88. PMID 15923238 DOI: 10.1529/Biophysj.104.050682  0.575
2005 Tae G, Kornfield JA, Hubbell JA. Sustained release of human growth hormone from in situ forming hydrogels using self-assembly of fluoroalkyl-ended poly(ethylene glycol). Biomaterials. 26: 5259-66. PMID 15792553 DOI: 10.1016/J.Biomaterials.2005.01.042  0.328
2005 Missirlis D, Tirelli N, Hubbell JA. Amphiphilic hydrogel nanoparticles. Preparation, characterization, and preliminary assessment as new colloidal drug carriers. Langmuir : the Acs Journal of Surfaces and Colloids. 21: 2605-13. PMID 15752059 DOI: 10.1021/La047367S  0.575
2005 van de Wetering P, Metters AT, Schoenmakers RG, Hubbell JA. Poly(ethylene glycol) hydrogels formed by conjugate addition with controllable swelling, degradation, and release of pharmaceutically active proteins. Journal of Controlled Release : Official Journal of the Controlled Release Society. 102: 619-27. PMID 15681084 DOI: 10.1016/J.Jconrel.2004.10.029  0.313
2005 Trentin D, Hubbell J, Hall H. Non-viral gene delivery for local and controlled DNA release. Journal of Controlled Release : Official Journal of the Controlled Release Society. 102: 263-75. PMID 15653151 DOI: 10.1016/J.Jconrel.2004.09.029  0.301
2005 Metters A, Hubbell J. Network formation and degradation behavior of hydrogels formed by Michael-type addition reactions Biomacromolecules. 6: 290-301. PMID 15638532 DOI: 10.1021/Bm049607O  0.316
2005 Lutolf MP, Hubbell JA. Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nature Biotechnology. 23: 47-55. PMID 15637621 DOI: 10.1038/Nbt1055  0.615
2005 Rehor A, Hubbell JA, Tirelli N. Oxidation-sensitive polymeric nanoparticles. Langmuir : the Acs Journal of Surfaces and Colloids. 21: 411-7. PMID 15620332 DOI: 10.1021/La0478043  0.555
2005 Schmoekel HG, Weber FE, Schense JC, Grätz KW, Schawalder P, Hubbell JA. Bone repair with a form of BMP-2 engineered for incorporation into fibrin cell ingrowth matrices. Biotechnology and Bioengineering. 89: 253-62. PMID 15619323 DOI: 10.1002/Bit.20168  0.342
2005 Pittier R, Sauthier F, Hubbell JA, Hall H. Neurite extension and in vitro myelination within three-dimensional modified fibrin matrices. Journal of Neurobiology. 63: 1-14. PMID 15616962 DOI: 10.1002/Neu.20116  0.345
2005 Ehrbar M, Metters A, Zammaretti P, Hubbell JA, Zisch AH. Endothelial cell proliferation and progenitor maturation by fibrin-bound VEGF variants with differential susceptibilities to local cellular activity Journal of Controlled Release. 101: 93-109. PMID 15588897 DOI: 10.1016/J.Jconrel.2004.07.018  0.324
2005 Urech L, Bittermann AG, Hubbell JA, Hall H. Mechanical properties, proteolytic degradability and biological modifications affect angiogenic process extension into native and modified fibrin matrices in vitro. Biomaterials. 26: 1369-79. PMID 15482824 DOI: 10.1016/J.Biomaterials.2004.04.045  0.326
2005 Kao WJ, Hubbell JA, Anderson JM. Protein-mediated macrophage adhesion and activation on biomaterials: a model for modulating cell behavior. Journal of Materials Science. Materials in Medicine. 10: 601-5. PMID 15347973 DOI: 10.1023/A:1008971222932  0.679
2005 Fittkau MH, Zilla P, Bezuidenhout D, Lutolf MP, Human P, Hubbell JA, Davies N. The selective modulation of endothelial cell mobility on RGD peptide containing surfaces by YIGSR peptides Biomaterials. 26: 167-174. PMID 15207463 DOI: 10.1016/J.Biomaterials.2004.02.012  0.585
2005 Rehor A, Botterhuis NE, Hubbell JA, Sommerdijk NAJM, Tirelli N. Glucose sensitivity through oxidation responsiveness. An example of cascade-responsive nano-sensors Journal of Materials Chemistry. 15: 4006. DOI: 10.1039/B510998A  0.513
2005 Feller LM, Cerritelli S, Textor M, Hubbell JA, Tosatti SGP. Influence of poly(propylene sulfide-block-ethylene glycol) di- And triblock copolymer architecture on the formation of molecular adlayers on gold surfaces and their effect on protein resistance: A candidate for surface modification in biosensor research Macromolecules. 38: 10503-10510. DOI: 10.1021/Ma051424M  0.331
2005 Cerritelli S, Fontana A, Velluto D, Adrian M, Dubochet J, De Maria P, Hubbell JA. Thermodynamic and Kinetic Effects in the Aggregation Behavior of a Poly(ethylene glycol-b-propylene sulfide-b-ethylene glycol)ABATriblock Copolymer Macromolecules. 38: 7845-7851. DOI: 10.1021/Ma051176U  0.304
2005 Segura T, Hubbell JA. 217. Synthesis and Characterization of a Smart Triblock Copolymer Carrier for siRNA Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.220  0.6
2005 Hall H, Hubbell JA. Modified Fibrin Hydrogels stimulate Angiogenesisin vivo: potential Application to increase Perfusion of Ischemic Tissues Materialwissenschaft Und Werkstofftechnik. 36: 768-774. DOI: 10.1002/Mawe.200500966  0.358
2004 Napoli A, Boerakker MJ, Tirelli N, Nolte RJ, Sommerdijk NA, Hubbell JA. Glucose-oxidase based self-destructing polymeric vesicles. Langmuir : the Acs Journal of Surfaces and Colloids. 20: 3487-91. PMID 15875368 DOI: 10.1021/La0357054  0.54
2004 Cellesi F, Weber W, Fussenegger M, Hubbell JA, Tirelli N. Towards a fully synthetic substitute of alginate: optimization of a thermal gelation/chemical cross-linking scheme ("tandem" gelation) for the production of beads and liquid-core capsules. Biotechnology and Bioengineering. 88: 740-9. PMID 15532084 DOI: 10.1002/Bit.20264  0.575
2004 Goessl A, Tirelli N, Hubbell JA. A hydrogel system for stimulus-responsive, oxygen-sensitive in situ gelation. Journal of Biomaterials Science. Polymer Edition. 15: 895-904. PMID 15318799 DOI: 10.1163/1568562041271039  0.559
2004 Park Y, Lutolf MP, Hubbell JA, Hunziker EB, Wong M. Bovine primary chondrocyte culture in synthetic matrix metalloproteinase-sensitive poly(ethylene glycol)-based hydrogels as a scaffold for cartilage repair. Tissue Engineering. 10: 515-22. PMID 15165468 DOI: 10.1089/107632704323061870  0.579
2004 Cellesi F, Tirelli N, Hubbell JA. Towards a fully-synthetic substitute of alginate: development of a new process using thermal gelation and chemical cross-linking. Biomaterials. 25: 5115-24. PMID 15109835 DOI: 10.1016/J.Biomaterials.2003.12.015  0.578
2004 Ehrbar M, Djonov VG, Schnell C, Tschanz SA, Martiny-Baron G, Schenk U, Wood J, Burri PH, Hubbell JA, Zisch AH. Cell-demanded liberation of VEGF121 from fibrin implants induces local and controlled blood vessel growth. Circulation Research. 94: 1124-32. PMID 15044320 DOI: 10.1161/01.Res.0000126411.29641.08  0.319
2004 Schmoekel H, Schense JC, Weber FE, Grätz KW, Gnägi D, Müller R, Hubbell JA. Bone healing in the rat and dog with nonglycosylated BMP-2 demonstrating low solubility in fibrin matrices. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 22: 376-81. PMID 15013099 DOI: 10.1016/S0736-0266(03)00188-8  0.516
2004 Pratt AB, Weber FE, Schmoekel HG, Müller R, Hubbell JA. Synthetic extracellular matrices for in situ tissue engineering. Biotechnology and Bioengineering. 86: 27-36. PMID 15007838 DOI: 10.1002/Bit.10897  0.581
2004 Napoli A, Valentini M, Tirelli N, Müller M, Hubbell JA. Oxidation-responsive polymeric vesicles Nature Materials. 3: 183-189. PMID 14991021 DOI: 10.1038/Nmat1081  0.568
2004 Schoenmakers RG, van de Wetering P, Elbert DL, Hubbell JA. The effect of the linker on the hydrolysis rate of drug-linked ester bonds. Journal of Controlled Release : Official Journal of the Controlled Release Society. 95: 291-300. PMID 14980777 DOI: 10.1016/J.Jconrel.2003.12.009  0.757
2004 Zisch AH, Zeisberger SM, Ehrbar M, Djonov V, Weber CC, Ziemiecki A, Pasquale EB, Hubbell JA. Engineered fibrin matrices for functional display of cell membrane-bound growth factor-like activities: study of angiogenic signaling by ephrin-B2. Biomaterials. 25: 3245-57. PMID 14980419 DOI: 10.1016/J.Biomaterials.2003.10.015  0.339
2004 Valentini M, Vaccaro A, Rehor A, Napoli A, Hubbell JA, Tirelli N. Diffusion NMR spectroscopy for the characterization of the size and interactions of colloidal matter: the case of vesicles and nanoparticles. Journal of the American Chemical Society. 126: 2142-7. PMID 14971949 DOI: 10.1021/Ja037247R  0.536
2004 Tosatti S, Schwartz Z, Campbell C, Cochran DL, VandeVondele S, Hubbell JA, Denzer A, Simpson J, Wieland M, Lohmann CH, Textor M, Boyan BD. RGD-containing peptide GCRGYGRGDSPG reduces enhancement of osteoblast differentiation by poly(L-lysine)-graft-poly(ethylene glycol)-coated titanium surfaces. Journal of Biomedical Materials Research. Part A. 68: 458-72. PMID 14762925 DOI: 10.1002/Jbm.A.20082  0.333
2004 Hall H, Bozic D, Michel K, Hubbell JA. N-terminal alpha-dystroglycan binds to different extracellular matrix molecules expressed in regenerating peripheral nerves in a protein-mediated manner and promotes neurite extension of PC12 cells. Molecular and Cellular Neurosciences. 24: 1062-73. PMID 14697669 DOI: 10.1016/J.Mcn.2003.08.007  0.321
2004 Zisch AH, Lutolf MP, Hubbell JA. Biopolymeric delivery matrices for angiogenic growth factors. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 12: 295-310. PMID 14630296 DOI: 10.1016/S1054-8807(03)00089-9  0.575
2004 Hubbell JA. Materials as morphogenetic guides in tissue engineering. Current Opinion in Biotechnology. 14: 551-8. PMID 14580588 DOI: 10.1016/J.Copbio.2003.09.004  0.318
2004 Lutolf MP, Hubbell JA. Synthesis and physicochemical characterization of end-linked poly(ethylene glycol)-co-peptide hydrogels formed by Michael-type addition. Biomacromolecules. 4: 713-22. PMID 12741789 DOI: 10.1021/Bm025744E  0.574
2004 Thurner P, Müller B, Sennhauser U, Hubbell J, Müller R. Tomography studies of biological cells on polymer scaffolds Journal of Physics: Condensed Matter. 16: S3499-S3510. DOI: 10.1088/0953-8984/16/33/011  0.317
2004 Lussi JW, Michel R, Reviakine I, Falconnet D, Goessl A, Csucs G, Hubbell JA, Textor M. A novel generic platform for chemical patterning of surfaces Progress in Surface Science. 76: 55-69. DOI: 10.1016/J.Progsurf.2004.05.013  0.315
2003 Zisch AH, Lutolf MP, Ehrbar M, Raeber GP, Rizzi SC, Davies N, Schmökel H, Bezuidenhout D, Djonov V, Zilla P, Hubbell JA. Cell-demanded release of VEGF from synthetic, biointeractive cell ingrowth matrices for vascularized tissue growth Faseb Journal. 17: 2260-2262. PMID 14563693 DOI: 10.1096/Fj.02-1041Fje  0.601
2003 Tosatti S, De Paul SM, Askendal A, VandeVondele S, Hubbell JA, Tengvall P, Textor M. Peptide functionalized poly(L-lysine)-g-poly(ethylene glycol) on titanium: resistance to protein adsorption in full heparinized human blood plasma. Biomaterials. 24: 4949-58. PMID 14559008 DOI: 10.1016/S0142-9612(03)00420-4  0.328
2003 Heggli M, Tirelli N, Zisch A, Hubbell JA. Michael-type addition as a tool for surface functionalization. Bioconjugate Chemistry. 14: 967-73. PMID 13129400 DOI: 10.1021/Bc0340621  0.557
2003 Hubbell JA. Materials science. Enhancing drug function. Science (New York, N.Y.). 300: 595-6. PMID 12714733 DOI: 10.1126/Science.1083625  0.305
2003 Lutolf MP, Weber FE, Schmoekel HG, Schense JC, Kohler T, Müller R, Hubbell JA. Repair of bone defects using synthetic mimetics of collagenous extracellular matrices. Nature Biotechnology. 21: 513-8. PMID 12704396 DOI: 10.1038/Nbt818  0.674
2003 VandeVondele S, Vörös J, Hubbell JA. RGD-grafted poly-L-lysine-graft-(polyethylene glycol) copolymers block non-specific protein adsorption while promoting cell adhesion. Biotechnology and Bioengineering. 82: 784-790. PMID 12701144 DOI: 10.1002/Bit.10625  0.363
2003 Bearinger JP, Terrettaz S, Michel R, Tirelli N, Vogel H, Textor M, Hubbell JA. Chemisorbed poly(propylene sulphide)-based copolymers resist biomolecular interactions. Nature Materials. 2: 259-64. PMID 12690400 DOI: 10.1038/Nmat851  0.594
2003 Lutolf MP, Lauer-Fields JL, Schmoekel HG, Metters AT, Weber FE, Fields GB, Hubbell JA. Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: engineering cell-invasion characteristics. Proceedings of the National Academy of Sciences of the United States of America. 100: 5413-8. PMID 12686696 DOI: 10.1073/Pnas.0737381100  0.588
2003 Vernon B, Tirelli N, Bächi T, Haldimann D, Hubbell JA. Water-borne, in situ crosslinked biomaterials from phase-segregated precursors. Journal of Biomedical Materials Research. Part A. 64: 447-56. PMID 12579558 DOI: 10.1002/Jbm.A.10369  0.568
2003 Park YD, Tirelli N, Hubbell JA. Photopolymerized hyaluronic acid-based hydrogels and interpenetrating networks. Biomaterials. 24: 893-900. PMID 12504509 DOI: 10.1016/S0142-9612(02)00420-9  0.581
2003 Valentini M, Napoli A, Tirelli N, Hubbell JA. Precise Determination of the Hydrophobic/Hydrophilic Junction in Polymeric Vesicles Langmuir. 19: 4852-4855. DOI: 10.1021/La026896Y  0.533
2003 Thurner P, Müller B, Beckmann F, Weitkamp T, Rau C, Müller R, Hubbell JA, Sennhauser U. Tomography studies of human foreskin fibroblasts on polymer yarns Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions With Materials and Atoms. 200: 397-405. DOI: 10.1016/S0168-583X(02)01729-9  0.307
2003 Ju YM, Ahn K, Kim JM, Hubbell JA, Han DK. Physical Properties and Biodegradation of Lactide-based Poly(ethy1ene glycol) Polymer Networks for Tissue Engineering Polymer Bulletin. 50: 107-114. DOI: 10.1007/S00289-003-0132-5  0.325
2003 Tae G, Lammertink RGH, Kornfield JA, Hubbell JA. Facile hydrophilic surface modification of poly(tetrafluoroethylene) using fluoroalkyl-terminated poly(ethylene glycol)s Advanced Materials. 15: 66-69. DOI: 10.1002/Adma.200390013  0.317
2003 Lutolf M, Raeber G, Zisch A, Tirelli N, Hubbell J. Cell-Responsive Synthetic Hydrogels Advanced Materials. 15: 888-892. DOI: 10.1002/Adma.200304621  0.698
2002 Halstenberg S, Panitch A, Rizzi S, Hall H, Hubbell JA. Biologically engineered protein-graft-poly(ethylene glycol) hydrogels: a cell adhesive and plasmin-degradable biosynthetic material for tissue repair. Biomacromolecules. 3: 710-23. PMID 12099815 DOI: 10.1021/Bm015629O  0.378
2002 Tirelli N, Lutolf MP, Napoli A, Hubbell JA. Poly(ethylene glycol) block copolymers. Journal of Biotechnology. 90: 3-15. PMID 12069046 DOI: 10.1016/S1389-0352(01)00057-5  0.693
2002 Winblade ND, Schmökel H, Baumann M, Hoffman AS, Hubbell JA. Sterically blocking adhesion of cells to biological surfaces with a surface-active copolymer containing poly(ethylene glycol) and phenylboronic acid. Journal of Biomedical Materials Research. 59: 618-31. PMID 11774323 DOI: 10.1002/Jbm.1273  0.379
2002 Hall H, Baechi T, Hubbell JA. Molecular properties of fibrin-based matrices for promotion of angiogenesis in vitro. Microvascular Research. 62: 315-26. PMID 11678634 DOI: 10.1006/Mvre.2001.2348  0.368
2002 Rehor A, Tirelli N, Hubbell JA. A New Living Emulsion Polymerization Mechanism:  Episulfide Anionic Polymerization Macromolecules. 35: 8688-8693. DOI: 10.1021/Ma0211378  0.571
2002 Napoli A, Tirelli N, Wehrli E, Hubbell JA. Lyotropic Behavior in Water of Amphiphilic ABA Triblock Copolymers Based on Poly(propylene sulfide) and Poly(ethylene glycol) Langmuir. 18: 8324-8329. DOI: 10.1021/La025897N  0.56
2002 Michel R, Lussi JW, Csucs G, Reviakine I, Danuser G, Ketterer B, Hubbell JA, Textor M, Spencer ND. Selective molecular assembly patterning: A new approach to micro- and nanochemical patterning of surfaces for biological applications Langmuir. 18: 3281-3287. DOI: 10.1021/La011715Y  0.315
2002 Bontempo D, Tirelli N, Feldman K, Masci G, Crescenzi V, Hubbell J. Atom Transfer Radical Polymerization as a Tool for Surface Functionalization Advanced Materials. 14: 1239-1241. DOI: 10.1002/1521-4095(20020903)14:17<1239::Aid-Adma1239>3.0.Co;2-P  0.539
2002 Cellesi F, Tirelli N, Hubbell JA. Materials for cell encapsulation via a new tandem approach combining reverse thermal gelation and covalent crosslinking Macromolecular Chemistry and Physics. 203: 1466-1472. DOI: 10.1002/1521-3935(200207)203:10/11<1466::Aid-Macp1466>3.0.Co;2-P  0.572
2001 Elbert DL, Hubbell JA. Conjugate addition reactions combined with free-radical cross-linking for the design of materials for tissue engineering Biomacromolecules. 2: 430-441. PMID 11749203 DOI: 10.1021/Bm0056299  0.784
2001 Lutolf MP, Tirelli N, Cerritelli S, Cavalli L, Hubbell JA. Systematic modulation of Michael-type reactivity of thiols through the use of charged amino acids. Bioconjugate Chemistry. 12: 1051-6. PMID 11716699 DOI: 10.1021/Bc015519E  0.659
2001 Elbert DL, Pratt AB, Lutolf MP, Halstenberg S, Hubbell JA. Protein delivery from materials formed by self-selective conjugate addition reactions. Journal of Controlled Release : Official Journal of the Controlled Release Society. 76: 11-25. PMID 11532309 DOI: 10.1016/S0168-3659(01)00398-4  0.783
2001 Kao WJ, Lee D, Schense JC, Hubbell JA. Fibronectin modulates macrophage adhesion and FBGC formation: The role of RGD, PHSRN, and PRRARV domains Journal of Biomedical Materials Research. 55: 79-88. PMID 11426401 DOI: 10.1002/1097-4636(200104)55:1<79::Aid-Jbm110>3.0.Co;2-Z  0.615
2001 Zisch AH, Schenk U, Schense JC, Sakiyama-Elbert SE, Hubbell JA. Covalently conjugated VEGF-fibrin matrices for endothelialization Journal of Controlled Release. 72: 101-113. PMID 11389989 DOI: 10.1016/S0168-3659(01)00266-8  0.606
2001 Sakiyama-Elbert SE, Panitch A, Hubbell JA. Development of growth factor fusion proteins for cell-triggered drug delivery The Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1300-1302. PMID 11344120 DOI: 10.1096/Fj.00-0564Fje  0.601
2001 Sakiyama-Elbert SE, Hubbell JA. Functional biomaterials: Design of novel biomaterials Annual Review of Materials Science. 31: 183-201. DOI: 10.1146/Annurev.Matsci.31.1.183  0.588
2001 Tae G, Kornfield JA, Hubbell JA, Johannsmann D, Hogen-Esch TE. Hydrogels with controlled, surface erosion characteristics from self-assembly of fluoroalkyl-ended poly(ethylene glycol) Macromolecules. 34: 6409-6419. DOI: 10.1021/Ma0107511  0.325
2001 Huang NP, Michel R, Voros J, Textor M, Hofer R, Rossi A, Elbert DL, Hubbell JA, Spencer ND. Poly(L-lysine)-g-poly(ethylene glycol) layers on metal oxide surfaces: surface-analytical characterization and resistance to serum and fibrinogen adsorption Langmuir. 17: 489-498. DOI: 10.1021/La000736+  0.762
2000 Winblade ND, Nikolic ID, Hoffman AS, Hubbell JA. Blocking adhesion to cell and tissue surfaces by the chemisorption of a poly-L-lysine-graft-(poly(ethylene glycol); phenylboronic acid) copolymer. Biomacromolecules. 1: 523-33. PMID 11710177 DOI: 10.1021/Bm000040V  0.363
2000 Sakiyama-Elbert SE, Hubbell JA. Controlled release of nerve growth factor from a heparin-containing fibrin-based cell ingrowth matrix Journal of Controlled Release. 69: 149-158. PMID 11018553 DOI: 10.1016/S0168-3659(00)00296-0  0.618
2000 Ye Q, Zünd G, Benedikt P, Jockenhoevel S, Hoerstrup SP, Sakyama S, Hubbell JA, Turina M. Fibrin gel as a three dimensional matrix in cardiovascular tissue engineering. European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association For Cardio-Thoracic Surgery. 17: 587-91. PMID 10814924 DOI: 10.1016/S1010-7940(00)00373-0  0.338
2000 Schense JC, Bloch J, Aebischer P, Hubbell JA. Enzymatic incorporation of bioactive peptides into fibrin matrices enhances neurite extension Nature Biotechnology. 18: 415-419. PMID 10748522 DOI: 10.1038/74473  0.315
2000 Sakiyama-Elbert SE, Hubbell JA. Development of fibrin derivatives for controlled release of heparin- binding growth factors Journal of Controlled Release. 65: 389-402. PMID 10699297 DOI: 10.1016/S0168-3659(99)00221-7  0.628
2000 Sakiyama SE, Schense JC, Hubbell JA. Incorporation of heparin-binding peptides into fibrin gels enhances neurite extension: an example of designer matrices in tissue engineering. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 13: 2214-24. PMID 10593869 DOI: 10.1096/Fasebj.13.15.2214  0.323
2000 Razatos A, Ong YL, Boulay F, Elbert DL, Hubbell JA, Sharma MM, Georgiou G. Force measurements between bacteria and poly(ethylene glycol)-coated surfaces Langmuir. 16: 9155-9158. DOI: 10.1021/La000818Y  0.756
2000 Kenausis GL, Vörös J, Elbert DL, Huang N, Hofer R, Ruiz-Taylor L, Textor M, Hubbell JA, Spencer ND. Poly(l-lysine)-g-Poly(ethylene glycol) Layers on Metal Oxide Surfaces: Attachment Mechanism and Effects of Polymer Architecture on Resistance to Protein Adsorption† Journal of Physical Chemistry B. 104: 3298-3309. DOI: 10.1021/Jp993359M  0.767
2000 Zisch AH, Schenk U, Schweitzer B, Sakiyama-Elbert S, Schense J, Hubbell J. Fibrin-based matrices for angio genic stimulation Journal of Vascular Surgery. 31: 1303-1305. DOI: 10.1016/S0741-5214(00)90141-1  0.581
1999 Cruise GM, Hegre OD, Lamberti FV, Hager SR, Hill R, Scharp DS, Hubbell JA. In vitro and in vivo performance of porcine islets encapsulated in interfacially photopolymerized poly(ethylene glycol) diacrylate membranes. Cell Transplantation. 8: 293-306. PMID 10442742 DOI: 10.1177/096368979900800310  0.304
1999 West JL, Hubbell JA. Polymeric Biomaterials with Degradation Sites for Proteases Involved in Cell Migration Macromolecules. 32: 241-244. DOI: 10.1021/Ma981296K  0.55
1999 Elbert DL, Herbert CB, Hubbell JA. Thin polymer layers formed by polyelectrolyte multilayer techniques on biological surfaces Langmuir. 15: 5355-5362. DOI: 10.1021/La9815749  0.776
1998 Kao WJ, Hubbell JA. Murine macrophage behavior on peptide-grafted polyethyleneglycol- containing networks Biotechnology and Bioengineering. 59: 2-9. PMID 10099308 DOI: 10.1002/(Sici)1097-0290(19980705)59:1<2::Aid-Bit2>3.0.Co;2-G  0.603
1998 Elbert DL, Hubbell JA. Reduction of fibrous adhesion formation by a copolymer possessing an affinity for anionic surfaces Journal of Biomedical Materials Research. 42: 55-65. PMID 9740007 DOI: 10.1002/(Sici)1097-4636(199810)42:1<55::Aid-Jbm8>3.0.Co;2-N  0.786
1998 Han DK, Park KD, Hubbell JA, Kim YH. Surface characteristics and biocompatibility of lactide-based poly(ethylene glycol) scaffolds for tissue engineering Journal of Biomaterials Science-Polymer Edition. 9: 667-680. PMID 9686334 DOI: 10.1163/156856298X00082  0.337
1998 Hubbell JA. Biomaterials in tissue engineering. Bio/Technology (Nature Publishing Company). 13: 565-76. PMID 9634795 DOI: 10.1038/Nbt0695-565  0.379
1998 Elbert DL, Hubbell JA. Self-assembly and steric stabilization at heterogeneous, biological surfaces using adsorbing block copolymers Chemistry and Biology. 5: 177-183. PMID 9545428 DOI: 10.1016/S1074-5521(98)90062-X  0.784
1998 Hern DL, Hubbell JA. Incorporation of adhesion peptides into nonadhesive hydrogels useful for tissue resurfacing. Journal of Biomedical Materials Research. 39: 266-76. PMID 9457557 DOI: 10.1002/(Sici)1097-4636(199802)39:2<266::Aid-Jbm14>3.0.Co;2-B  0.337
1998 Hubbell JA. Synthetic biodegradable polymers for tissue engineering and drug delivery Current Opinion in Solid State and Materials Science. 3: 246-251. DOI: 10.1016/S1359-0286(98)80098-3  0.349
1997 Han DK, Hubbell JA. Synthesis of Polymer Network Scaffolds froml-Lactide and Poly(ethylene glycol) and Their Interaction with Cells Macromolecules. 30: 6077-6083. DOI: 10.1021/Ma970302U  0.351
1997 Noh I, Hubbell JA. Photograft polymerization of acrylate monomers and macromonomers on photochemically reduced PTFE films Journal of Polymer Science Part a: Polymer Chemistry. 35: 3467-3482. DOI: 10.1002/(Sici)1099-0518(19971130)35:16<3467::Aid-Pola14>3.0.Co;2-D  0.308
1996 West JL, Hubbell JA. Separation of the arterial wall from blood contact using hydrogel barriers reduces intimal thickening after balloon injury in the rat: the roles of medial and luminal factors in arterial healing. Proceedings of the National Academy of Sciences of the United States of America. 93: 13188-93. PMID 8917566 DOI: 10.1073/Pnas.93.23.13188  0.51
1996 West JL, Hubbell JA. Comparison of covalently and physically cross-linked polyethylene glycol-based hydrogels for the prevention of postoperative adhesions in a rat model. Biomaterials. 16: 1153-6. PMID 8562791 DOI: 10.1016/0142-9612(95)93579-3  0.539
1996 Hill-West JL, Dunn RC, Hubbell JA. Local release of fibrinolytic agents for adhesion prevention. The Journal of Surgical Research. 59: 759-63. PMID 8538178 DOI: 10.1006/Jsre.1995.1236  0.34
1996 Han DK, Hubbell JA. Lactide-Based Poly(ethylene glycol) Polymer Networks for Scaffolds in Tissue Engineering Macromolecules. 29: 5233-5235. DOI: 10.1021/Ma9601070  0.318
1996 Cruise GM, Hegre OD, Hager S, Hill R, Scharp D, Hubbell JA. Poly(ethylene glycol) based encapsulation of islets of langerhans Cell Transplantation. 5: 52. DOI: 10.1016/0963-6897(96)82228-7  0.325
1996 Hubbell JA. Hydrogel systems for barriers and local drug delivery in the control of wound healing Journal of Controlled Release. 39: 305-313. DOI: 10.1016/0168-3659(95)00162-X  0.373
1995 Drumheller PD, Hubbell JA. Polymer networks with grafted cell adhesion peptides for highly biospecific cell adhesive substrates. Analytical Biochemistry. 222: 380-8. PMID 7864362 DOI: 10.1006/Abio.1994.1506  0.352
1995 Pathak CP, Sawhney AS, Quinn CP, Hubbell JA. Polyimide-polyethylene glycol block copolymers: Synthesis, characterization, and initial evaluation as a biomaterial Journal of Biomaterials Science-Polymer Edition. 6: 313-323. PMID 7841141 DOI: 10.1163/156856295X00021  0.328
1995 Drumheller PD, Hubbell JA. Densely crosslinked polymer networks of poly(ethylene glycol) in trimethylolpropane triacrylate for cell-adhesion-resistant surfaces. Journal of Biomedical Materials Research. 29: 207-15. PMID 7738068 DOI: 10.1002/Jbm.820290211  0.363
1995 West JL, Hubbell JA. Photopolymerized hydrogel materials for drug delivery applications Reactive Polymers. 25: 139-147. DOI: 10.1016/0923-1137(94)00096-N  0.571
1994 Sawhney AS, Pathak CP, van Rensburg JJ, Dunn RC, Hubbell JA. Optimization of photopolymerized bioerodible hydrogel properties for adhesion prevention. Journal of Biomedical Materials Research. 28: 831-8. PMID 8083251 DOI: 10.1002/Jbm.820280710  0.348
1994 Sawhney AS, Pathak P, Hubbell JA. Modification of islet of langerhans surfaces with immunoprotective poly(ethylene glycol) coatings via inferfacial photopolymerization Biotechnology and Bioengineering. 44: 383-386. DOI: 10.1002/Bit.260440317  0.351
1993 Sawhney AS, Pathak CP, Hubbell JA. Interfacial photopolymerization of poly(ethylene glycol)-based hydrogels upon alginate-poly(l-lysine) microcapsules for enhanced biocompatibility Biomaterials. 14: 1008-1016. PMID 8286667 DOI: 10.1016/0142-9612(93)90194-7  0.341
1993 Sawhney AS, Hubbell JA. Poly(ethylene oxide)-graft-poly(L-lysine) copolymers to enhance the biocompatibility of poly(L-lysine)-alginate microcapsule membranes. Biomaterials. 13: 863-70. PMID 1457680 DOI: 10.1016/0142-9612(92)90180-V  0.35
1993 Sawhney AS, Pathak CP, Hubbell JA. Bioerodible hydrogels based on photopolymerized poly(ethylene glycol)-co-poly(.alpha.-hydroxy acid) diacrylate macromers Macromolecules. 26: 581-587. DOI: 10.1021/Ma00056A005  0.307
1992 Hubbell JA, Massia SP, Drumheller PD. Surface-grafted cell-binding peptides in tissue engineering of the vascular graft Annals of the New York Academy of Sciences. 665: 253-258. PMID 1416607 DOI: 10.1111/J.1749-6632.1992.Tb42589.X  0.316
1992 Wagner WR, Hubbell JA. ADP Receptor Antagonists and Converting Enzyme Systems Reduce Platelet Deposition onto Collagen Thrombosis and Haemostasis. 67: 461-467. DOI: 10.1055/S-0038-1648471  0.465
1992 Pathak CP, Sawhney AS, Hubbell JA. Rapid photopolymerization of immunoprotective gels in contact with cells and tissue Journal of the American Chemical Society. 114: 8311-8312. DOI: 10.1021/Ja00047A065  0.323
1991 Desai NP, Hubbell JA. The short-term blood biocompatibility of poly(hydroxyethyl methacrylate-co-methyl methacrylate) in an in vitro flow system measured by digital videomicroscopy. Journal of Biomaterials Science. Polymer Edition. 1: 123-46. PMID 2488848 DOI: 10.1163/156856289X00118  0.318
1991 Sawhney AS, Hubbell JA. Rapidly degraded terpolymers of dl-lactide, glycolide, and epsilon-caprolactone with increased hydrophilicity by copolymerization with polyethers. Journal of Biomedical Materials Research. 24: 1397-411. PMID 2283356 DOI: 10.1002/Jbm.820241011  0.335
1991 Desai NP, Hubbell JA. Biological responses to polyethylene oxide modified polyethylene terephthalate surfaces. Journal of Biomedical Materials Research. 25: 829-43. PMID 1833405 DOI: 10.1002/Jbm.820250704  0.321
1991 Desai NP, Hubbell JA. Solution technique to incorporate polyethylene oxide and other water-soluble polymers into surfaces of polymeric biomaterials. Biomaterials. 12: 144-53. PMID 1831675 DOI: 10.1016/0142-9612(91)90193-E  0.329
1991 Massia SP, Hubbell JA. Human endothelial cell interactions with surface-coupled adhesion peptides on a nonadhesive glass substrate and two polymeric biomaterials Journal of Biomedical Materials Research. 25: 223-242. PMID 1829082 DOI: 10.1002/Jbm.820250209  0.361
1991 Massia SP, Hubbell JA. An RGD spacing of 440 nm is sufficient for integrin αvβ3-mediated fibroblast spreading and 140 nm for focal contact and stress fiber formation Journal of Cell Biology. 114: 1089-1100. PMID 1714913 DOI: 10.1083/Jcb.114.5.1089  0.322
1991 Hubbell JA, Pohl PI, Wagner WR. The Use of Laser-Light Scattering and Controlled Shear in Platelet Aggregometry Thrombosis and Haemostasis. 65: 601-607. DOI: 10.1055/S-0038-1648197  0.459
1991 Hubbell JA, Massia SP, Desai NP, Drumheller PD. Endothelial cell-selective materials for tissue engineering in the vascular graft via a new receptor Nature Biotechnology. 9: 568-572. DOI: 10.1038/Nbt0691-568  0.339
1990 Massia SP, Hubbell JA. Convalent surface immobilization of Arg-Gly-Asp- and Tyr-Ile-Gly-Ser-Arg-containing peptides to obtain well-defined cell-adhesive substrates Analytical Biochemistry. 187: 292-301. PMID 2382830 DOI: 10.1016/0003-2697(90)90459-M  0.333
1990 Massia SP, Hubbell JA. Covalently attached GRGD on polymer surfaces promotes biospecific adhesion of mammalian cells Annals of the New York Academy of Sciences. 589: 261-270. PMID 2141461 DOI: 10.1111/J.1749-6632.1990.Tb24251.X  0.347
1986 Hubbell JA, McIntire LV. Platelet active concentration profiles near growing thrombi. A mathematical consideration. Biophysical Journal. 50: 937-45. PMID 3790695 DOI: 10.1016/S0006-3495(86)83535-4  0.519
1986 Hubbell JA, McIntire LV. Visualization and analysis of mural thrombogenesis on collagen, polyurethane and nylon. Biomaterials. 7: 354-63. PMID 3778995 DOI: 10.1016/0142-9612(86)90006-2  0.521
1986 Hubbell JA, McIntire LV. Technique for visualization and analysis of mural thrombogenesis Review of Scientific Instruments. 57: 892-897. DOI: 10.1063/1.1138830  0.5
Low-probability matches (unlikely to be authored by this person)
2016 Pinnagoda K, Larsson HM, Vythilingam G, Vardar E, Engelhardt EM, Thambidorai RC, Hubbell JA, Frey P. Engineered acellular collagen scaffold for endogenous cell guidance, a novel approach in urethral regeneration. Acta Biomaterialia. PMID 27450527 DOI: 10.1016/J.Actbio.2016.07.033  0.3
2014 Tomei AA, Manzoli V, Fraker CA, Giraldo J, Velluto D, Najjar M, Pileggi A, Molano RD, Ricordi C, Stabler CL, Hubbell JA. Device design and materials optimization of conformal coating for islets of Langerhans Proceedings of the National Academy of Sciences of the United States of America. 111: 10514-10519. PMID 24982192 DOI: 10.1073/Pnas.1402216111  0.3
2005 Ihm JE, Han KO, Hwang CS, Kang JH, Ahn KD, Han IK, Han DK, Hubbell JA, Cho CS. Poly (4-vinylimidazole) as nonviral gene carrier: in vitro and in vivo transfection. Acta Biomaterialia. 1: 165-72. PMID 16701793 DOI: 10.1016/J.Actbio.2004.12.002  0.3
2010 van der Vlies AJ, O'Neil CP, Hasegawa U, Hammond N, Hubbell JA. Synthesis of pyridyl disulfide-functionalized nanoparticles for conjugating thiol-containing small molecules, peptides, and proteins. Bioconjugate Chemistry. 21: 653-62. PMID 20369815 DOI: 10.1021/Bc9004443  0.299
2020 Ishihara A, Ishihara J, Watkins EA, Tremain AC, Nguyen M, Solanki A, Katsumata K, Mansurov A, Budina E, Alpar AT, Hosseinchi P, Maillat L, Reda JW, Kageyama T, Swartz MA, ... ... Hubbell JA, et al. Publisher Correction: Prolonged residence of an albumin-IL-4 fusion protein in secondary lymphoid organs ameliorates experimental autoimmune encephalomyelitis. Nature Biomedical Engineering. PMID 33093659 DOI: 10.1038/s41551-020-00649-x  0.299
2008 Salaklang J, Steitz B, Finka A, O'Neil CP, Moniatte M, van der Vlies AJ, Giorgio TD, Hofmann H, Hubbell JA, Petri-Fink A. Superparamagnetic nanoparticles as a powerful systems biology characterization tool in the physiological context. Angewandte Chemie (International Ed. in English). 47: 7857-60. PMID 18792049 DOI: 10.1002/Anie.200800357  0.299
2010 Mercanzini A, Reddy ST, Velluto D, Colin P, Maillard A, Bensadoun JC, Hubbell JA, Renaud P. Controlled release nanoparticle-embedded coatings reduce the tissue reaction to neuroprostheses. Journal of Controlled Release : Official Journal of the Controlled Release Society. 145: 196-202. PMID 20447428 DOI: 10.1016/J.Jconrel.2010.04.025  0.298
1992 Desai NP, Hubbell JA. Tissue response to intraperitoneal implants of polyethylene oxide-modified polyethylene terephthalate. Biomaterials. 13: 505-10. PMID 1385984 DOI: 10.1016/0142-9612(92)90101-S  0.297
2010 Martino MM, Hubbell JA. The 12th-14th type III repeats of fibronectin function as a highly promiscuous growth factor-binding domain Faseb Journal. 24: 4711-4721. PMID 20671107 DOI: 10.1096/Fj.09-151282  0.296
2015 Ihm JE, Krier I, Lim JM, Shim S, Han DK, Hubbell JA. Improved biocompatibility of polyethylenimine (PEI) as a gene carrier by conjugating urocanic acid: In vitro and in vivo Macromolecular Research. DOI: 10.1007/S13233-015-3047-8  0.296
2015 Grimm AJ, Kontos S, Diaceri G, Quaglia-Thermes X, Hubbell JA. Memory of tolerance and induction of regulatory T cells by erythrocyte-targeted antigens. Scientific Reports. 5: 15907. PMID 26511151 DOI: 10.1038/Srep15907  0.296
2016 Brubaker CE, Panagiotou V, Demurtas D, Bonner DK, Swartz MA, Hubbell JA. A Cationic Micelle Complex Improves CD8+ T Cell Responses in Vaccination Against Unmodified Protein Antigen Acs Biomaterial Science and Engineering. 2: 231-240. DOI: 10.1021/Acsbiomaterials.5B00456  0.295
2009 Rothenfluh DA, Hubbell JA. Integration column: biofunctional polymeric nanoparticles for spatio-temporal control of drug delivery and biomedical applications. Integrative Biology : Quantitative Biosciences From Nano to Macro. 1: 446-51. PMID 20023754 DOI: 10.1039/B907627C  0.295
2012 Sawhney AS, Hubbell JA. In situ photopolymerized hydrogels for vascular and peritoneal wound healing. Methods in Molecular Medicine. 18: 85-100. PMID 21370170 DOI: 10.1385/0-89603-516-6:85  0.295
2005 Weber CC, Cai H, Ehrbar M, Kubota H, Martiny-Baron G, Weber W, Djonov V, Weber E, Mallik AS, Fussenegger M, Frei K, Hubbell JA, Zisch AH. Effects of protein and gene transfer of the angiopoietin-1 fibrinogen-like receptor-binding domain on endothelial and vessel organization. The Journal of Biological Chemistry. 280: 22445-53. PMID 15781448 DOI: 10.1074/Jbc.M410367200  0.294
2008 Cerritelli S, Velluto D, Hubbell JA, Fontana A. Breakdown kinetics of aggregates from poly(ethylene glycol-bl-propylene sulfide) di- and triblock copolymers induced by a non-ionic surfactant Journal of Polymer Science, Part a: Polymer Chemistry. 46: 2477-2487. DOI: 10.1002/Pola.22580  0.294
2010 Kontos S, Hubbell JA. Improving protein pharmacokinetics by engineering erythrocyte affinity Molecular Pharmaceutics. 7: 2141-2147. PMID 20831257 DOI: 10.1021/Mp1001697  0.293
1996 Herbert CB, Hernandez AM, Hubbell JA. Platelet adhesion to polyurethane blended with polytetramethylene oxide. Biotechnology and Bioengineering. 52: 81-8. PMID 18629853 DOI: 10.1002/(Sici)1097-0290(19961005)52:1<81::Aid-Bit7>3.0.Co;2-V  0.293
2011 Eming SA, Hubbell JA. Extracellular matrix in angiogenesis: Dynamic structures with translational potential Experimental Dermatology. 20: 605-613. PMID 21692861 DOI: 10.1111/J.1600-0625.2011.01309.X  0.293
2019 Briquez PS, Hauert S, Repond G, Swartz MA, Hubbell JA. Abstract 1217: Exploiting host pre-existing immunity for melanoma cancer immunotherapy Cancer Research. 79: 1217-1217. DOI: 10.1158/1538-7445.Am2019-1217  0.293
2003 Kusonwiriyawong C, van de Wetering P, Hubbell JA, Merkle HP, Walter E. Evaluation of pH-dependent membrane-disruptive properties of poly(acrylic acid) derived polymers. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fã¼R Pharmazeutische Verfahrenstechnik E.V. 56: 237-46. PMID 12957638 DOI: 10.1016/S0939-6411(03)00093-6  0.293
1999 Schense JC, Hubbell JA. Cross-linking exogenous bifunctional peptides into fibrin gels with factor XIIIa. Bioconjugate Chemistry. 10: 75-81. PMID 9893967 DOI: 10.1021/Bc9800769  0.293
2009 Bearinger JP, Stone G, Dugan LC, El Dasher B, Stockton C, Conway JW, Kuenzler T, Hubbell JA. Porphyrin-based photocatalytic nanolithography: a new fabrication tool for protein arrays. Molecular & Cellular Proteomics : McP. 8: 1823-31. PMID 19406753 DOI: 10.1074/Mcp.M800585-Mcp200  0.293
1998 Shoichet MS, Hubbell JA. Polymers for tissue engineering Journal of Biomaterials Science, Polymer Edition. 9: 405-406. DOI: 10.1163/156856298X00523  0.293
2009 Arrighi I, Mark S, Alvisi M, von Rechenberg B, Hubbell JA, Schense JC. Bone healing induced by local delivery of an engineered parathyroid hormone prodrug. Biomaterials. 30: 1763-71. PMID 19124152 DOI: 10.1016/J.Biomaterials.2008.12.023  0.293
2008 Hubbell JA. Cellular matrices: Physiology in microfluidics Nature Materials. 7: 609-610. PMID 18654581 DOI: 10.1038/Nmat2238  0.292
1995 Quinn CP, Pathak CP, Heller A, Hubbell JA. Photo-crosslinked copolymers of 2-hydroxyethyl methacrylate, poly(ethylene glycol) tetra-acrylate and ethylene dimethacrylate for improving biocompatibility of biosensors. Biomaterials. 16: 389-96. PMID 7662824 DOI: 10.1016/0142-9612(95)98856-9  0.292
2013 Jang M, Lee ST, Kim JW, Yang JH, Yoon JK, Park JC, Ryoo HM, van der Vlies AJ, Ahn JY, Hubbell JA, Song YS, Lee G, Lim JM. A feeder-free, defined three-dimensional polyethylene glycol-based extracellular matrix niche for culture of human embryonic stem cells. Biomaterials. 34: 3571-80. PMID 23422594 DOI: 10.1016/J.Biomaterials.2013.01.073  0.292
2005 Hubbell JA. Tissue and cell engineering. Current Opinion in Biotechnology. 15: 381-2. PMID 15464365 DOI: 10.1016/J.Copbio.2004.08.015  0.292
2006 Trentin D, Hall H, Wechsler S, Hubbell JA. Peptide-matrix-mediated gene transfer of an oxygen-insensitive hypoxia-inducible factor-1alpha variant for local induction of angiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 103: 2506-11. PMID 16477043 DOI: 10.1073/Pnas.0505964102  0.292
2010 Vasdekis AE, O'Neil CP, Hubbell JA, Psaltis D. Microfluidic assays for DNA manipulation based on a block copolymer immobilization strategy. Biomacromolecules. 11: 827-31. PMID 20158193 DOI: 10.1021/Bm901453U  0.292
1996 Chowdhury SM, Hubbell JA. Adhesion prevention with ancrod released via a tissue-adherent hydrogel. The Journal of Surgical Research. 61: 58-64. PMID 8769943 DOI: 10.1006/Jsre.1996.0081  0.292
2012 Friedl P, Hubbell J, Livingston D, Mihich E. Twenty-third annual Pezcoller Symposium: engineering influences in cancer research. Cancer Research. 72: 841-4. PMID 22237623 DOI: 10.1158/0008-5472.Can-11-3080  0.292
2005 Lussi JW, Falconnet D, Hubbell JA, Textor M, Csucs G. Pattern stability under cell culture conditions--a comparative study of patterning methods based on PLL-g-PEG background passivation. Biomaterials. 27: 2534-41. PMID 16364431 DOI: 10.1016/J.Biomaterials.2005.11.027  0.291
2006 Hubbell JA. Matrix-bound growth factors in tissue repair. Swiss Medical Weekly. 136: 387. DOI: 10.4414/Smw.2006.11402  0.291
2012 Hubbell JA, Chilkoti A. Nanomaterials for drug delivery Science. 337: 303-305. PMID 22822138 DOI: 10.1126/Science.1219657  0.29
2018 Potin L, Maillat L, Briquez PS, Hubbell JA, Swartz MA. Abstract 1750: Inducing therapeutic lymphangiogenesis for potentiating cancer immunotherapy in melanoma Cancer Research. 78: 1750-1750. DOI: 10.1158/1538-7445.Am2018-1750  0.29
2015 Martino MM, Briquez PS, Maruyama K, Hubbell JA. Extracellular matrix-inspired growth factor delivery systems for bone regeneration. Advanced Drug Delivery Reviews. PMID 25895621 DOI: 10.1016/J.Addr.2015.04.007  0.289
2015 Briquez PS, Hubbell JA, Martino MM. Extracellular Matrix-Inspired Growth Factor Delivery Systems for Skin Wound Healing. Advances in Wound Care. 4: 479-489. PMID 26244104 DOI: 10.1089/Wound.2014.0603  0.289
2002 Tae G, Kornfield JA, Hubbell JA, Lal J. Ordering transitions of fluoroalkyl-ended poly(ethylene glycol): Rheology and SANS Macromolecules. 35: 4448-4457. DOI: 10.1021/Ma011809E  0.289
2007 Reidy M, Zihlmann P, Hubbell JA, Hall H. Activation of cell-survival transcription factor NFkappaB in L1Ig6-stimulated endothelial cells. Journal of Biomedical Materials Research. Part A. 77: 542-50. PMID 16493660 DOI: 10.1002/Jbm.A.30590  0.289
2014 Larsson HM, Gorostidi F, Hubbell JA, Barrandon Y, Frey P. Clonal, self-renewing and differentiating human and porcine urothelial cells, a novel stem cell population. Plos One. 9: e90006. PMID 24587183 DOI: 10.1371/Journal.Pone.0090006  0.288
2000 Schense JC, Hubbell JA. Three-dimensional migration of neurites is mediated by adhesion site density and affinity. The Journal of Biological Chemistry. 275: 6813-8. PMID 10702239 DOI: 10.1074/Jbc.275.10.6813  0.288
1991 Drumheller PD, Hubbell JA. Local modulation of intracellular calcium levels near a single-cell wound in human endothelial monolayers. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology. 11: 1258-65. PMID 1911711 DOI: 10.1161/01.Atv.11.5.1258  0.287
2020 Zhou R, Weathered R, Kurtanich T, Mezyk-Kopec R, Mansurov A, Hubbell J, Swartz MA. Abstract B28: Development and validation of a novel organotypic in vitro model of the tumor-lymph-immune interface for predicting immunotherapy resistance Cancer Research. 80. DOI: 10.1158/1538-7445.Camodels2020-B28  0.287
2009 Bearinger JP, Stone G, Hiddessen AL, Dugan LC, Wu L, Hailey P, Conway JW, Kuenzler T, Feller L, Cerritelli S, Hubbell JA. Phototocatalytic lithography of poly(propylene sulfide) block copolymers: toward high-throughput nanolithography for biomolecular arraying applications. Langmuir : the Acs Journal of Surfaces and Colloids. 25: 1238-44. PMID 19113808 DOI: 10.1021/La802727S  0.286
1994 Drumheller PD, Hubbell JA. Phase-mixed poly(ethylene glycol)/poly(trimethylolpropane triacrylate) semi-interpenetrating polymer networks obtained by rapid network formation Journal of Polymer Science Part a: Polymer Chemistry. 32: 2715-2725. DOI: 10.1002/Pola.1994.080321412  0.286
2017 Oxburgh L, Carroll TJ, Cleaver O, Gossett DR, Hoshizaki DK, Hubbell JA, Humphreys BD, Jain S, Jensen J, Kaplan DL, Kesselman C, Ketchum CJ, Little MH, McMahon AP, Shankland SJ, et al. (Re)Building a Kidney. Journal of the American Society of Nephrology : Jasn. PMID 28096308 DOI: 10.1681/Asn.2016101077  0.285
2005 Hubbell JA. Biomaterials science and high-throughput screening. Nature Biotechnology. 22: 828-9. PMID 15229544 DOI: 10.1038/Nbt0704-828  0.285
1998 Cruise GM, Hegre OD, Scharp DS, Hubbell JA. A sensitivity study of the key parameters in the interfacial photopolymerization of poly(ethylene glycol) diacrylate upon porcine islets. Biotechnology and Bioengineering. 57: 655-665. PMID 10099245 DOI: 10.1002/(Sici)1097-0290(19980320)57:6<655::Aid-Bit3>3.0.Co;2-K  0.285
2009 Pugin R, Blondiaux N, Popa AM, Niedermann P, Liley M, Giazzon M, Matthey N, Hubbell JA, Heinzelmann H. Surface nanopatterning by polymer self-assembly: From applied research to industrial applications Journal of Photopolymer Science and Technology. 22: 229-233. DOI: 10.2494/Photopolymer.22.223  0.285
1999 Hubbell JA. Biotechnology. A new-for-old urinary bladder. Nature. 398: 198-9. PMID 10094041 DOI: 10.1038/18322  0.285
2015 Najjar M, Manzoli V, Abreu M, Villa C, Martino MM, Molano RD, Torrente Y, Pileggi A, Inverardi L, Ricordi C, Hubbell JA, Tomei AA. Fibrin gels engineered with pro-angiogenic growth factors promote engraftment of pancreatic islets in extrahepatic sites in mice. Biotechnology and Bioengineering. 112: 1916-26. PMID 25786390 DOI: 10.1002/Bit.25589  0.284
2003 Bearinger JP, Vörös J, Hubbell JA, Textor M. Electrochemical optical waveguide lightmode spectroscopy (EC‐OWLS): A pilot study using evanescent‐field optical sensing under voltage control to monitor polycationic polymer adsorption onto indium tin oxide (ITO)‐coated waveguide chips Biotechnology and Bioengineering. 82: 465-473. PMID 12632403 DOI: 10.1002/Bit.10591  0.283
2013 Husseini GA, Velluto D, Kherbeck L, Pitt WG, Hubbell JA, Christensen DA. Investigating the acoustic release of doxorubicin from targeted micelles Colloids and Surfaces B: Biointerfaces. 101: 153-155. PMID 22796785 DOI: 10.1016/J.Colsurfb.2012.05.025  0.283
2010 Ramseyer P, Micol LA, Engelhardt EM, Osterheld MC, Hubbell JA, Frey P. In vivo study of an injectable poly(acrylonitrile)-based hydrogel paste as a bulking agent for the treatment of urinary incontinence. Biomaterials. 31: 4613-9. PMID 20303170 DOI: 10.1016/J.Biomaterials.2010.02.021  0.283
2019 Sasaki K, Ishihara J, Ishihara A, Miura R, Mansurov A, Fukunaga K, Hubbell JA. Engineered collagen-binding serum albumin as a drug conjugate carrier for cancer therapy. Science Advances. 5: eaaw6081. PMID 31453327 DOI: 10.1126/Sciadv.Aaw6081  0.283
2007 Walpoth BH, Zammaretti P, Cikirikcioglu M, Khabiri E, Djebaili MK, Pache JC, Tille JC, Aggoun Y, Morel D, Kalangos A, Hubbell JA, Zisch AH. Enhanced intimal thickening of expanded polytetrafluoroethylene grafts coated with fibrin or fibrin-releasing vascular endothelial growth factor in the pig carotid artery interposition model. The Journal of Thoracic and Cardiovascular Surgery. 133: 1163-70. PMID 17467424 DOI: 10.1016/J.Jtcvs.2007.01.029  0.283
2017 Manzoli V, Villa C, Bayer AL, Morales L, Molano RD, Torrente Y, Ricordi C, Hubbell JA, Tomei AA. Immunoisolation of Murine Islet Allografts in Vascularized Sites Through Conformal Coating with Polyethylene Glycol. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 29068143 DOI: 10.1111/Ajt.14547  0.282
2009 Bearinger JP, Dugan LC, Wu L, Hill H, Christian AT, Hubbell JA. Chemical tethering of motile bacteria to silicon surfaces Biotechniques. 46: 209-216. PMID 19317664 DOI: 10.2144/000113073  0.282
1994 Hossainy SF, Hubbell JA. Molecular weight dependence of calcification of polyethylene glycol hydrogels. Biomaterials. 15: 921-5. PMID 7833441 DOI: 10.1016/0142-9612(94)90118-X  0.282
1994 Hill-West JL, Chowdhury SM, Slepian MJ, Hubbell JA. Inhibition of thrombosis and intimal thickening by in situ photopolymerization of thin hydrogel barriers. Proceedings of the National Academy of Sciences of the United States of America. 91: 5967-71. PMID 8016098 DOI: 10.1073/Pnas.91.13.5967  0.281
2010 Hubbell JA. Drug development: Longer-lived proteins. Nature. 467: 1051-2. PMID 20981086 DOI: 10.1038/4671051A  0.28
2019 Ishihara A, Ishihara J, Hubbell JA, Swartz MA. Collagen affinity improves efficacy and safety of antibody and cytokine cancer immunotherapy. Journal of Clinical Oncology. 37: e14232-e14232. DOI: 10.1200/Jco.2019.37.15_Suppl.E14232  0.279
2019 Ishihara J, Ishihara A, Mansurov A, Sasaki K, Lee SS, Williford J, Potin L, Hosseinchi P, Gray LT, Katsumata K, Kron SJ, Swartz MA, Hubbell JA. Abstract 1553: Collagen affinity improves safety and efficacy of antibody and cytokine cancer immunotherapies Cancer Research. 79: 1553-1553. DOI: 10.1158/1538-7445.Am2019-1553  0.279
2019 Williford J, Ishihara J, Ishihara A, Mansurov A, Swartz MA, Hubbell JA. Abstract 2270: Recruitment of CD103+DCs via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy Cancer Research. 79: 2270-2270. DOI: 10.1158/1538-7445.Sabcs18-2270  0.277
1997 Slepian MJ, Hubbell JA. Polymeric endoluminal gel paving: hydrogel systems for local barrier creation and site-specific drug delivery Advanced Drug Delivery Reviews. 24: 11-30. DOI: 10.1016/S0169-409X(96)00479-6  0.277
2005 Karrer L, Duwe J, Zisch AH, Khabiri E, Cikirikcioglu M, Napoli A, Goessl A, Schaffner T, Hess OM, Carrel T, Kalangos A, Hubbell JA, Walpoth BH. PPS-PEG surface coating to reduce thrombogenicity of small diameter ePTFE vascular grafts. The International Journal of Artificial Organs. 28: 993-1002. PMID 16288437 DOI: 10.1177/039139880502801006  0.277
2013 Lee K, Hubbell JA. Tissue, cell and engineering. Current Opinion in Biotechnology. 24: 827-9. PMID 24018131 DOI: 10.1016/J.Copbio.2013.08.001  0.277
2000 An Y, Hubbell JA. Intraarterial protein delivery via intimally-adherent bilayer hydrogels. Journal of Controlled Release : Official Journal of the Controlled Release Society. 64: 205-15. PMID 10640658 DOI: 10.1016/S0168-3659(99)00143-1  0.276
2013 De Laporte L, Rice JJ, Tortelli F, Hubbell JA. Tenascin C Promiscuously Binds Growth Factors via Its Fifth Fibronectin Type III-Like Domain Plos One. 8. PMID 23637968 DOI: 10.1371/Journal.Pone.0062076  0.276
2013 Garcia-Cordero JL, Nembrini C, Stano A, Hubbell JA, Maerkl SJ. A high-throughput nanoimmunoassay chip applied to large-scale vaccine adjuvant screening. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 650-8. PMID 23443913 DOI: 10.1039/C3Ib20263A  0.275
1994 Hill-West JL, Chowdhury SM, Dunn RC, Hubbell JA. Efficacy of a resorbable hydrogel barrier, oxidized regenerated cellulose, and hyaluronic acid in the prevention of ovarian adhesions in a rabbit model. Fertility and Sterility. 62: 630-634. PMID 8062961 DOI: 10.1016/S0015-0282(16)56956-8  0.275
2015 Hubbell JA. Prescription for a pharmacyte. Science Translational Medicine. 7: 291fs23. PMID 26062842 DOI: 10.1126/Scitranslmed.Aac5665  0.275
2019 Lih E, Park W, Park KW, Chun SY, Kim H, Joung YK, Kwon TG, Hubbell JA, Han DK. A Bioinspired Scaffold with Anti-Inflammatory Magnesium Hydroxide and Decellularized Extracellular Matrix for Renal Tissue Regeneration. Acs Central Science. 5: 458-467. PMID 30937373 DOI: 10.1021/Acscentsci.8B00812  0.275
1995 Drumheller PD, Hubbell JA. Analysis of phase mixing in aged polymer networks of poly(ethylene glycol) and poly(trimethylolpropane triacrylate) Polymer. 36: 883-885. DOI: 10.1016/0032-3861(95)93122-3  0.275
1993 Hubbell JA. Chapter 11 Pharmacologic modification of materials Cardiovascular Pathology. 2: 121-127. DOI: 10.1016/1054-8807(93)90052-4  0.274
1992 Desai NP, Hossainy SF, Hubbell JA. Surface-immobilized polyethylene oxide for bacterial repellence. Biomaterials. 13: 417-20. PMID 1385983 DOI: 10.1016/0142-9612(92)90160-P  0.274
2010 Meo EMD, Crescenzo AD, Velluto D, O'Neil CP, Demurtas D, Hubbell JA, Fontana A. Erratum: Assessing the role of poly(ethylene glycol-bl-propylene sulfide) (peg-pps) block copolymers in the preparation of carbon nanotube biocompatible dispersions (Macromolecules (2010) 43 (3429)) Macromolecules. 43: 7872-7873. DOI: 10.1021/Ma101683F  0.273
2008 Ehrbar M, Zeisberger SM, Raeber GP, Hubbell JA, Schnell C, Zisch AH. The role of actively released fibrin-conjugated VEGF for VEGF receptor 2 gene activation and the enhancement of angiogenesis. Biomaterials. 29: 1720-9. PMID 18155761 DOI: 10.1016/J.Biomaterials.2007.12.002  0.273
2005 Hall H, Hubbell JA. Matrix-bound sixth Ig-like domain of cell adhesion molecule L1 acts as an angiogenic factor by ligating alphavbeta3-integrin and activating VEGF-R2. Microvascular Research. 68: 169-78. PMID 15501236 DOI: 10.1016/J.Mvr.2004.07.001  0.27
2000 Deutsch M, Meinhart J, Scheme J, Hubbell J, Zilla PP. Endothelial cell seeding: Revisiting the issues Journal of Vascular Surgery. 31: 1265-1268. DOI: 10.1016/S0741-5214(00)90124-1  0.27
2005 Meinhart JG, Schense JC, Schima H, Gorlitzer M, Hubbell JA, Deutsch M, Zilla P. Enhanced endothelial cell retention on shear-stressed synthetic vascular grafts precoated with RGD-cross-linked fibrin. Tissue Engineering. 11: 887-95. PMID 15998228 DOI: 10.1089/Ten.2005.11.887  0.27
2012 Vallée JP, Hauwel M, Lepetit-Coiffée M, Bei W, Montet-Abou K, Meda P, Gardier S, Zammaretti P, Kraehenbuehl TP, Herrmann F, Hubbell JA, Jaconi ME. Embryonic stem cell-based cardiopatches improve cardiac function in infarcted rats Stem Cells Translational Medicine. 1: 248-260. PMID 23197784 DOI: 10.5966/Sctm.2011-0028  0.27
1994 Hubbell JA, Palsson BO, Papoutsakis ET. Preface: Tissue engineering and cell therapies: II. Biotechnology and Bioengineering. 43: 683. PMID 18615791 DOI: 10.1002/Bit.260430802  0.269
1996 Hubbell JA. In Situ Material Transformations in Tissue Engineering Mrs Bulletin. 21: 33-35. DOI: 10.1557/S0883769400031821  0.269
2012 Yu SS, Lau CM, Thomas SN, Gray Jerome W, Maron DJ, Dickerson JH, Hubbell JA, Giorgio TD. Size- and charge-dependent non-specific uptake of PEGylated nanoparticles by macrophages International Journal of Nanomedicine. 7: 799-813. PMID 22359457 DOI: 10.2147/Ijn.S28531  0.268
1996 Herbert CB, Bittner GD, Hubbell JA. Effects of fibinolysis on neurite growth from dorsal root ganglia cultured in two- and three-dimensional fibrin gels. The Journal of Comparative Neurology. 365: 380-91. PMID 8822177 DOI: 10.1002/(Sici)1096-9861(19960212)365:3<380::Aid-Cne4>3.0.Co;2-0  0.268
2008 Bearinger JP, Stone G, Christian AT, Dugan L, Hiddessen AL, Wu KJ, Wu L, Hamilton J, Stockton C, Hubbell JA. Porphyrin-based photocatalytic lithography. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 5179-84. PMID 18380510 DOI: 10.1021/La703992R  0.267
1998 Cruise GM, Scharp DS, Hubbell JA. Characterization of permeability and network structure of interfacially photopolymerized poly(ethylene glycol) diacrylate hydrogels Biomaterials. 19: 1287-1294. PMID 9720892 DOI: 10.1016/S0142-9612(98)00025-8  0.267
2011 Di Crescenzo A, Velluto D, Hubbell JA, Fontana A. Biocompatible dispersions of carbon nanotubes: A potential tool for intracellular transport of anticancer drugs Nanoscale. 3: 925-928. PMID 21180768 DOI: 10.1039/C0Nr00444H  0.267
2020 Romero P, Donda A, Hubbell JA. An optimized antigen-protein fusion. Nature Biomedical Engineering. 4: 583-584. PMID 32533123 DOI: 10.1038/S41551-020-0572-3  0.267
2002 Windecker S, Grigioni KS, Hubbell JA, Schaffner T, Walpoth B, Mettler D, Eberli FR, Meier B, Hess OM. Comparison of a novel polymer (PLL-g-PEG) with gold-coated and stainless steel stents for prevention of neointimal hyperplasia Journal of the American College of Cardiology. 39: 26. DOI: 10.1016/S0735-1097(02)80110-3  0.265
1998 Herbert CB, Nagaswami C, Bittner GD, Hubbell JA, Weisel JW. Effects of fibrin micromorphology on neurite growth from dorsal root ganglia cultured in three-dimensional fibrin gels. Journal of Biomedical Materials Research. 40: 551-9. PMID 9599031 DOI: 10.1002/(Sici)1097-4636(19980615)40:4<551::Aid-Jbm6>3.0.Co;2-E  0.265
1997 Noh I, Chittur K, Goodman SL, Hubbell JA. Surface modification of poly(tetrafluoroethylene)with benzophenone and sodium hydride by ultraviolet irradiation Journal of Polymer Science Part a: Polymer Chemistry. 35: 1499-1514. DOI: 10.1002/(Sici)1099-0518(199706)35:8<1499::Aid-Pola19>3.0.Co;2-2  0.264
2008 Jo YS, Van Der Vlies AJ, Gantz J, Antonijevic S, Demurtas D, Velluto D, Hubbell JA. RAFT homo- and copolymerization of N-acryloyl-morpholine, piperidine, and azocane and their self-assembled structures Macromolecules. 41: 1140-1150. DOI: 10.1021/Ma071710T  0.264
2005 Hall H, Djonov V, Ehrbar M, Hoechli M, Hubbell JA. Heterophilic interactions between cell adhesion molecule L1 and alphavbeta3-integrin induce HUVEC process extension in vitro and angiogenesis in vivo. Angiogenesis. 7: 213-23. PMID 15609076 DOI: 10.1007/S10456-004-1328-5  0.263
2019 Katsumata K, Ishihara J, Mansurov A, Ishihara A, Raczy MM, Yuba E, Hubbell JA. Targeting inflammatory sites through collagen affinity enhances the therapeutic efficacy of anti-inflammatory antibodies. Science Advances. 5: eaay1971. PMID 31723606 DOI: 10.1126/Sciadv.Aay1971  0.262
2008 Dégano IR, Vilalta M, Bagó JR, Matthies AM, Hubbell JA, Dimitriou H, Bianco P, Rubio N, Blanco J. Bioluminescence imaging of calvarial bone repair using bone marrow and adipose tissue-derived mesenchymal stem cells Biomaterials. 29: 427-437. PMID 17950456 DOI: 10.1016/J.Biomaterials.2007.10.006  0.261
1992 Massia SP, Hubbell JA. Tissue engineering in the vascular graft Cytotechnology. 10: 189-204. PMID 1369235 DOI: 10.1007/Bf00146670  0.261
2016 Zielinski MS, Choi JW, La Grange T, Modestino MA, Hashemi SM, Pu Y, Birkhold S, Hubbell J, Psaltis D. Hollow Mesoporous Plasmonic Nanoshells for Enhanced Solar Vapor Generation. Nano Letters. PMID 26918518 DOI: 10.1021/Acs.Nanolett.5B03901  0.261
1992 Desai NP, Hubbell JA. Surface physical interpenetrating networks of poly(ethylene terephthalate) and poly(ethylene oxide) with biomedical applications Macromolecules. 25: 226-232. DOI: 10.1021/Ma00027A038  0.261
1993 Pathak CP, Sawhney AS, Hubbell JA. Rapid photopolymerization of immunoprotective gels in contact with cells and tissue. [Erratum to document cited in CA117(18):178203r] Journal of the American Chemical Society. 115: 2548-2548. DOI: 10.1021/Ja00059A084  0.261
2010 Lee ST, Yun JI, Jo YS, Mochizuki M, van der Vlies AJ, Kontos S, Ihm JE, Lim JM, Hubbell JA. Engineering integrin signaling for promoting embryonic stem cell self-renewal in a precisely defined niche. Biomaterials. 31: 1219-26. PMID 19926127 DOI: 10.1016/J.Biomaterials.2009.10.054  0.26
1993 Helmus MN, Hubbell JA. Chapter 6 Materials selection Cardiovascular Pathology. 2: 53-71. DOI: 10.1016/1054-8807(93)90047-6  0.258
2009 Lowery A, Finka A, Dorset D, Hubbell J, Giorgio T. Novel 7-mer peptide mediates nuclear targeting in MCF7 breast cancer cells Cancer Research. 69: 6023. DOI: 10.1158/0008-5472.Sabcs-6023  0.258
1996 Frautschi JR, Eberhart RC, Hubbell JA, Clark BD, Gelfand JA. Alkylation of cellulosic membranes results in reduced complement activation Journal of Biomaterials Science, Polymer Edition. 7: 707-714. PMID 8639479 DOI: 10.1163/156856296X00471  0.258
2005 Lussi JW, Tang C, Kuenzi PA, Staufer U, Csucs G, Vörös J, Danuser G, Hubbell JA, Textor M. Selective molecular assembly patterning at the nanoscale: A novel platform for producing protein patterns by electron-beam lithography on SiO 2/indium tin oxide-coated glass substrates Nanotechnology. 16: 1781-1786. DOI: 10.1088/0957-4484/16/9/062  0.257
2015 Husseinil GA, Kherbeckl L, Pitt WG, Hubbell JA, Christensen DA, Velluto D. Kinetics of Ultrasonic Drug Delivery from Targeted Micelles. Journal of Nanoscience and Nanotechnology. 15: 2099-104. PMID 26413626 DOI: 10.1166/Jnn.2015.9498  0.257
2012 Kontos S, Hubbell JA. Drug development: Longer-lived proteins Chemical Society Reviews. 41: 2686-2695. PMID 22310725 DOI: 10.1039/C2Cs15289D  0.257
1995 Frautschi JR, Eberhart RC, Hubbell JA. Alkylated cellulosic membranes with enhanced albumin affinity: influence of competing proteins Journal of Biomaterials Science. Polymer Edition. 7: 563-575. PMID 8924423 DOI: 10.1163/156856295X00481  0.255
2018 Larsson HM, Vythilingam G, Pinnagoda K, Vardar E, Engelhardt EM, Sothilingam S, Thambidorai RC, Kamarul T, Hubbell JA, Frey P. Fiber density of collagen grafts impacts rabbit urethral regeneration. Scientific Reports. 8: 10057. PMID 29968749 DOI: 10.1038/S41598-018-27621-9  0.255
2017 Vythilingam G, Larsson H, Pinnagoda K, Vardar E, Balet E, Thambidorai R, Kamarul T, Hubbell J, Frey P. Off the shelf tissue-engineered material for urethral reconstruction European Urology Supplements. 16: e1787-e1788. DOI: 10.1016/S1569-9056(17)31077-1  0.253
2018 Sevgen ES, de Pablo JJ, Hubbell JA. A Computational and Experimental Study of Crystallization-Driven Self-Assembly and Micelle Formation in Poly(Ethylene Glycol)-B-Oligo(Ethylene Sulfide) Biophysical Journal. 114: 528a. DOI: 10.1016/J.Bpj.2017.11.2886  0.251
2020 Hosseinchi P, Mansurov A, Maillat L, Potin L, Fujimori G, Hubbell JA, Swartz MA. Abstract 5695: Induction of lymphangiogenesis in breast cancer enhances responsiveness to immunotherapies Cancer Research. 80: 5695-5695. DOI: 10.1158/1538-7445.Am2020-5695  0.248
1994 Csöregi E, Quinn CP, Schmidtke DW, Lindquist SE, Pishko MV, Ye L, Katakis I, Hubbell JA, Heller A. Design, characterization, and one-point in vivo calibration of a subcutaneously implanted glucose electrode Analytical Chemistry. 66: 3131-3138. PMID 7978306 DOI: 10.1021/Ac00091A022  0.248
2004 Schmökel HG, Weber FE, Seiler G, von Rechenberg B, Schense JC, Schawalder P, Hubbell J. Treatment of nonunions with nonglycosylated recombinant human bone morphogenetic protein-2 delivered from a fibrin matrix. Veterinary Surgery : Vs. 33: 112-8. PMID 15027972 DOI: 10.1111/J.1532-950X.2004.04018.X  0.247
1995 Dumanian GA, Dascombe W, Hong C, Labadie K, Garrett K, Sawhney AS, Pathak CP, Hubbell JA, Johnson PC. A new photopolymerizable blood vessel glue that seals human vessel anastomoses without augmenting thrombogenicity Plastic and Reconstructive Surgery. 95: 901-907. DOI: 10.1097/00006534-199504001-00021  0.245
2005 Schmoekel HG, Weber FE, Hurter K, Schense JC, Seiler G, Ryrz U, Spreng D, Schawalder P, Hubbell J. Enhancement of bone healing using non-glycosylated rhBMP-2 released from a fibrin matrix in dogs and cats. The Journal of Small Animal Practice. 46: 17-21. PMID 15682735 DOI: 10.1111/J.1748-5827.2005.Tb00269.X  0.244
2002 Tae G, Kornfield JA, Hubbell JA, Johannsmann D. Anomalous sorption in thin films of fluoroalkyl-ended poly(ethylene glycol)s Langmuir. 18: 8241-8245. DOI: 10.1021/La020255L  0.24
2019 Watkins EA, Hubbell JA. Designing biofunctional immunotherapies Nature Reviews Materials. 4: 350-352. DOI: 10.1038/S41578-019-0096-1  0.237
2009 Popa AM, Niedermann P, Heinzelmann H, Hubbell JA, Pugin R. Fabrication of nanopore arrays and ultrathin silicon nitride membranes by block-copolymer-assisted lithography. Nanotechnology. 20: 485303. PMID 19880976 DOI: 10.1088/0957-4484/20/48/485303  0.236
2013 Hubbell JA, Langer R. Translating materials design to the clinic Nature Materials. 12: 963-966. PMID 24150414 DOI: 10.1038/Nmat3788  0.235
2019 Katsumata K, Ishihara J, Fukunaga K, Ishihara A, Yuba E, Budina E, Hubbell JA. Conferring extracellular matrix affinity enhances local therapeutic efficacy of anti-TNF-α antibody in a murine model of rheumatoid arthritis. Arthritis Research & Therapy. 21: 298. PMID 31870429 DOI: 10.1186/S13075-019-2075-8  0.224
1995 Quinn CP, Pishko MV, Schmidtke DW, Ishikawa M, Wagner JG, Raskin P, Hubbell JA, Heller A. Kinetics of glucose delivery to subcutaneous tissue in rats measured with 0.3-mm amperometric microsensors American Journal of Physiology - Endocrinology and Metabolism. 269. PMID 7631771 DOI: 10.1152/Ajpendo.1995.269.1.E155  0.222
2006 Hubbell JA. Non-viral gene delivery: multifunctional polyplexes as locally triggerable nonviral vectors. Gene Therapy. 13: 1371-1372. PMID 16541118 DOI: 10.1038/Sj.Gt.3302763  0.218
2011 Yu SS, Scherer RL, Ortega RA, Bell CS, O"Neil CP, Hubbell JA, Giorgio TD. Enzymatic- and temperature-sensitive controlled release of ultrasmall superparamagnetic iron oxides (USPIOs) (vol 9, pg 7, 2011) Journal of Nanobiotechnology. 9. DOI: 10.1186/1477-3155-9-51  0.213
2008 Tornay R, Braschler T, Demierre N, Steitz B, Finka A, Hofmann H, Hubbell JA, Renaud P. Dielectrophoresis-based particle exchanger for the manipulation and surface functionalization of particles. Lab On a Chip. 8: 267-73. PMID 18231665 DOI: 10.1039/B713776A  0.213
2018 Guo AZ, Sevgen E, Sidky H, Whitmer JK, Hubbell JA, de Pablo JJ. Adaptive enhanced sampling by force-biasing using neural networks. The Journal of Chemical Physics. 148: 134108. PMID 29626875 DOI: 10.1063/1.5020733  0.212
2010 Signarovitz AL, Ray HJ, Cong Y, Yu J, Berton M, Guentzel MN, Klose KE, Arulanandam BP, Zueva VS, Zubareva A, Zubkov D, Par'igina N, Il'ina AV, Svirshchevskaya E, Du Y, ... ... Hubbell JA, et al. Mucosal vaccines (PP-049) International Immunology. 22. DOI: 10.1093/Intimm/Dxq229  0.211
2001 Handel TM, Bertozzi C, Hubbell JA. Biopolymers - Biopolymer engineering and design: Beyond the genome Current Opinion in Chemical Biology. 5: 675-676. DOI: 10.1016/S1367-5931(01)00264-2  0.209
2020 Mitrousis N, Sasso MS, Weichselbaum RR, Hubbell JA, Swartz MA. Abstract 2253: Lymphangiogenesis augments the anti-tumor efficacy of radiotherapy in mouse melanoma Immunology. DOI: 10.1158/1538-7445.Am2020-2253  0.208
1992 Hossiany SF, Desai NP, Hubbell JA. Avoidance of photoactivation in the epifluorescence video microscopic observation of thrombosis. Journal of Biomedical Materials Research. 26: 1535-42. PMID 1447234 DOI: 10.1002/Jbm.820261111  0.198
2023 Wallace RP, Refvik KC, Antane JT, Brünggel K, Tremain AC, Raczy MR, Alpar AT, Nguyen M, Solanki A, Slezak AJ, Watkins EA, Lauterbach AL, Cao S, Wilson DS, Hubbell JA. Synthetically mannosylated antigens induce antigen-specific humoral tolerance and reduce anti-drug antibody responses to immunogenic biologics. Cell Reports. Medicine. 101345. PMID 38128533 DOI: 10.1016/j.xcrm.2023.101345  0.195
2024 Slezak AJ, Chang K, Beckman TN, Refvik KC, Alpar AT, Lauterbach AL, Solanki A, Kwon JW, Gomes S, Mansurov A, Hubbell JA. Cysteine-binding adjuvant enhances survival and promotes immune function in a murine model of acute myeloid leukemia. Blood Advances. PMID 38324726 DOI: 10.1182/bloodadvances.2023012529  0.193
2023 Wallace RP, Refvik KC, Antane JT, Br ºnggel K, Tremain AC, Raczy MR, Alpar AT, Nguyen M, Solanki A, Slezak AJ, Watkins EA, Lauterbach AL, Cao S, Wilson DS, Hubbell JA. Synthetically mannosylated antigens induce antigen-specific humoral tolerance and reduce anti-drug antibody responses to immunogenic biologics. Biorxiv : the Preprint Server For Biology. PMID 37066302 DOI: 10.1101/2023.04.07.534593  0.191
2009 Jo YS, van der Vlies AJ, Gantz J, Thacher TN, Antonijevic S, Cavadini S, Demurtas D, Stergiopulos N, Hubbell JA. Micelles for delivery of nitric oxide. Journal of the American Chemical Society. 131: 14413-8. PMID 19764751 DOI: 10.1021/ja905123t  0.186
2023 Schnorenberg MR, Hawley KM, Thomas-Toth AT, Watkins EA, Tian Y, Ting JM, Leak LB, Kucera IM, Raczy MM, Kung AL, Hubbell JA, Tirrell MV, LaBelle JL. Targeted Polymersome Delivery of a Stapled Peptide for Drugging the Tumor Protein p53:BCL-2-Family Axis in Diffuse Large B-Cell Lymphoma. Acs Nano. PMID 37688780 DOI: 10.1021/acsnano.3c04112  0.182
2010 HUBBELL JA. ChemInform Abstract: Synthetic Biodegradable Polymers for Tissue Engineering and Drug Delivery Cheminform. 29: no-no. DOI: 10.1002/chin.199851346  0.179
2021 Damo M, Wilson DS, Watkins EA, Hubbell JA. Soluble N-Acetylgalactosamine-Modified Antigens Enhance Hepatocyte-Dependent Antigen Cross-Presentation and Result in Antigen-Specific CD8 T Cell Tolerance Development. Frontiers in Immunology. 12: 555095. PMID 33746941 DOI: 10.3389/fimmu.2021.555095  0.179
2022 Weiss AM, Hossainy S, Rowan SJ, Hubbell JA, Esser-Kahn AP. Immunostimulatory Polymers as Adjuvants, Immunotherapies, and Delivery Systems. Macromolecules. 55: 6913-6937. PMID 36034324 DOI: 10.1021/acs.macromol.2c00854  0.178
2008 Engelhardt EM, Ananta M, Foroughi F, Mudera V, Brown RA, Hilborn J, Hubbell JA, Wurm FM, Adam M, Frey P. Collagen-PLA hybrid materials: A novel scaffold for human bladder cells 8th World Biomaterials Congress 2008. 2: 619.  0.174
2022 Liu J, Solanki A, White MJV, Hubbell JA, Briquez PS. Therapeutic use of α2-antiplasmin as an antifibrinolytic and hemostatic agent in surgery and regenerative medicine. Npj Regenerative Medicine. 7: 34. PMID 35773290 DOI: 10.1038/s41536-022-00230-x  0.172
2023 Li N, Li Y, Cheng Z, Liu Y, Dai Y, Kang S, Li S, Shan N, Wai S, Ziaja A, Wang Y, Strzalka J, Liu W, Zhang C, Gu X, ... Hubbell JA, et al. Bioadhesive polymer semiconductors and transistors for intimate biointerfaces. Science (New York, N.Y.). 381: 686-693. PMID 37561870 DOI: 10.1126/science.adg8758  0.17
2007 Martino M, Mochizuki M, Smith M, Hubbell JA, Barker T. Fibrin delivery of molecular variants of fibronectin central cell-binding domain that provide integrin-specific instructions to mesenchymal stem cells European Cells and Materials. 13: 22.  0.168
2023 Lauterbach AL, Slezak AJ, Wang R, Cao S, Raczy MM, Watkins EA, Jimenez CJM, Hubbell JA. Mannose-Decorated Co-Polymer Facilitates Controlled Release of Butyrate to Accelerate Chronic Wound Healing. Advanced Healthcare Materials. e2300515. PMID 37503634 DOI: 10.1002/adhm.202300515  0.168
2024 Slezak A, Chang K, Hossainy S, Mansurov A, Rowan SJ, Hubbell JA, Guler MO. Therapeutic synthetic and natural materials for immunoengineering. Chemical Society Reviews. PMID 38170619 DOI: 10.1039/d3cs00805c  0.167
2004 Kim DH, Haake A, Sun Y, Neild AP, Ihm JE, Dual J, Hubbell JA, Ju BK, Nelson BJ. High-throughput cell manipulation using ultrasound fields. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 4: 2571-4. PMID 17270799 DOI: 10.1109/IEMBS.2004.1403739  0.166
2008 Kraehenbuehl TP, Zammaretti P, Van Der Vlies AJ, Schoenmakers RG, Lutolf MP, Jaconi ME, Hubbell JA. Directed cardiac differentiation of P19 EC cells by 3D synthetic cell-responsive PEG-hydrogels 8th World Biomaterials Congress 2008. 3: 1671.  0.165
2010 Taghavi S, Oneil C, Hubbell JA. N-dimensional PEG hydrogel - block copolymer scaffolds for controlled mouse stem cell differentiation European Cells and Materials. 20: 46.  0.164
2021 Watkins EA, Antane JT, Roberts JL, Lorentz KM, Zuerndorfer S, Dunaif AC, Bailey LJ, Tremain AC, Nguyen M, De Loera RC, Wallace RP, Weathered RK, Kontos S, Hubbell JA. Persistent antigen exposure via the eryptotic pathway drives terminal T cell dysfunction. Science Immunology. 6. PMID 33637595 DOI: 10.1126/sciimmunol.abe1801  0.164
2023 Tremain AC, Wallace RP, Lorentz KM, Thornley TB, Antane JT, Raczy MR, Reda JW, Alpar AT, Slezak AJ, Watkins EA, Maulloo CD, Budina E, Solanki A, Nguyen M, Bischoff DJ, ... ... Hubbell JA, et al. Synthetically glycosylated antigens for the antigen-specific suppression of established immune responses. Nature Biomedical Engineering. PMID 37679570 DOI: 10.1038/s41551-023-01086-2  0.162
2014 Burger M, Di Maggio N, Largo R, Martin I, Scherberich A, Hubbell JA, Schaefer DJ, Banfi A. LOP42 Plastic and Reconstructive Surgery. 134: 392-393. DOI: 10.1097/01.Prs.0000452872.93385.8D  0.162
1999 Hubbell JA. Bioactive biomaterials. Current Opinion in Biotechnology. 10: 123-9. PMID 10209141 DOI: 10.1016/s0958-1669(99)80021-4  0.161
2021 White MJV, Briquez PS, White DAV, Hubbell JA. VEGF-A, PDGF-BB and HB-EGF engineered for promiscuous super affinity to the extracellular matrix improve wound healing in a model of type 1 diabetes. Npj Regenerative Medicine. 6: 76. PMID 34795305 DOI: 10.1038/s41536-021-00189-1  0.153
2011 Hubbell JA. Polymers in Tissue Engineering Macromolecular Engineering: Precise Synthesis, Materials Properties, Applications. 4: 2719-2742. DOI: 10.1002/9783527631421.ch65  0.152
2013 Lee K, Hubbell JA. Tissue, cell and engineering Current Opinion in Biotechnology. 24: 827-827. DOI: 10.1016/j.copbio.2013.08.001  0.152
2004 Hubbell JA. Tissue and cell engineering. Current Opinion in Biotechnology. 14: 517-9. PMID 14580582 DOI: 10.1016/j.copbio.2003.09.006  0.152
2007 Hubbell JA. Matrix-bound growth factors in tissue repair. Swiss Medical Weekly. 72S-76S. PMID 17874506  0.15
2021 Certelli A, Valente P, Uccelli A, Grosso A, Di Maggio N, D'Amico R, Briquez PS, Hubbell JA, Wolff T, Gürke L, Mujagic E, Gianni-Barrera R, Banfi A. Robust Angiogenesis and Arteriogenesis in the Skin of Diabetic Mice by Transient Delivery of Engineered VEGF and PDGF-BB Proteins in Fibrin Hydrogels. Frontiers in Bioengineering and Biotechnology. 9: 688467. PMID 34277588 DOI: 10.3389/fbioe.2021.688467  0.15
2019 Zielinski MS, Vardar E, Vythilingam G, Engelhardt EM, Hubbell JA, Frey P, Larsson HM. Quantitative intrinsic auto-cathodoluminescence can resolve spectral signatures of tissue-isolated collagen extracellular matrix. Communications Biology. 2: 69. PMID 30793047 DOI: 10.1038/s42003-019-0313-x  0.148
2011 Nembrini C, Stano A, Dane KY, Ballester M, Van Der Vlies A, Marsland BJ, Swartz MA, Hubbell JA. Nanoparticle conjugation of antigen enhances cytotoxic t cell responses in pulmonary vaccination 24th European Conference On Biomaterials - Annual Conference of the European Society For Biomaterials.  0.142
2006 Rothenfluh D, Bermudez H, Schoenmakers R, Hubbell J. P380 BIOFUNCTIONAL POLY(PROPYLENE SULFIDE) NANOPARTICLES FOR TARGETED DRUG DELIVERY: IDENTIFICATION OF A NOVEL TARGETING PEPTIDE FOR ARTICULAR CARTILAGE BY PHAGE DISPLAY Osteoarthritis and Cartilage. 14: S201-S202. DOI: 10.1016/S1063-4584(07)60824-3  0.139
2022 D'Amico R, Malucelli C, Uccelli A, Grosso A, Di Maggio N, Briquez PS, Hubbell JA, Wolff T, Gürke L, Mujagic E, Gianni-Barrera R, Banfi A. Therapeutic arteriogenesis by factor-decorated fibrin matrices promotes wound healing in diabetic mice. Journal of Tissue Engineering. 13: 20417314221119615. PMID 36093431 DOI: 10.1177/20417314221119615  0.136
1994 Hubbell JA, Palsson BO, Papoutsakis ET. Preface. Tissue engineering and cell therapies. Biotechnology and Bioengineering. 43: 541. PMID 18615753 DOI: 10.1002/bit.260430702  0.134
2021 Briquez PS, Tsai HM, Watkins EA, Hubbell JA. Engineered bridge protein with dual affinity for bone morphogenetic protein-2 and collagen enhances bone regeneration for spinal fusion. Science Advances. 7. PMID 34117071 DOI: 10.1126/sciadv.abh4302  0.133
2022 Burger MG, Grosso A, Briquez PS, Born GME, Lunger A, Schrenk F, Todorov A, Sacchi V, Hubbell JA, Schaefer DJ, Banfi A, Di Maggio N. Robust coupling of angiogenesis and osteogenesis by VEGF-decorated matrices for bone regeneration. Acta Biomaterialia. 149: 111-125. PMID 35835287 DOI: 10.1016/j.actbio.2022.07.014  0.132
2022 Wang R, Cao S, Bashir MEH, Hesser LA, Su Y, Hong SMC, Thompson A, Culleen E, Sabados M, Dylla NP, Campbell E, Bao R, Nonnecke EB, Bevins CL, Wilson DS, ... Hubbell JA, et al. Treatment of peanut allergy and colitis in mice via the intestinal release of butyrate from polymeric micelles. Nature Biomedical Engineering. PMID 36550307 DOI: 10.1038/s41551-022-00972-5  0.129
2015 Martino MM, Briquez PS, Maruyama K, Hubbell JA. Extracellular matrix-inspired growth factor delivery systems for bone regeneration Advanced Drug Delivery Reviews. DOI: 10.1016/j.addr.2015.04.007  0.128
2023 Li Y, Li N, Liu W, Prominski A, Kang S, Dai Y, Liu Y, Hu H, Wai S, Dai S, Cheng Z, Su Q, Cheng P, Wei C, Jin L, ... Hubbell JA, et al. Achieving tissue-level softness on stretchable electronics through a generalizable soft interlayer design. Nature Communications. 14: 4488. PMID 37495580 DOI: 10.1038/s41467-023-40191-3  0.127
2023 Cao S, Maulloo CD, Raczy MM, Sabados M, Slezak AJ, Nguyen M, Solanki A, Wallace RP, Shim HN, Wilson DS, Hubbell JA. Glycosylation-modified antigens as a tolerance-inducing vaccine platform prevent anaphylaxis in a pre-clinical model of food allergy. Cell Reports. Medicine. 101346. PMID 38128531 DOI: 10.1016/j.xcrm.2023.101346  0.125
2007 Mercanzini A, Reddy S, Velluto D, Colin P, Maillard A, Bensadoun JC, Bertsch A, Hubbell JA, Renaud P. Controlled release drug coatings on flexible neural probes. Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual International Conference. 2007: 6613-6. PMID 18003541 DOI: 10.1109/IEMBS.2007.4353875  0.124
2024 Cao S, Budina E, Raczy MM, Solanki A, Nguyen M, Beckman TN, Reda JW, Hultgren K, Ang PS, Slezak AJ, Hesser LA, Alpar AT, Refvik KC, Shores LS, Pillai I, ... ... Hubbell JA, et al. A serine-conjugated butyrate prodrug with high oral bioavailability suppresses autoimmune arthritis and neuroinflammation in mice. Nature Biomedical Engineering. PMID 38561491 DOI: 10.1038/s41551-024-01190-x  0.12
2004 Lippold BS, Schmoekel HG, Weber FE, Schense JC, Hubbell JA, Ueltschi G, Brehm W. The use of nonglycosylated recombinanthuman bone morphogenic protein 2 (rhBMP-2) released from a fibrin matrix to promote arthridesis in an equine pastern joint Pferdeheilkunde Equine Medicine. 20: 442-446. DOI: 10.21836/pem20040505  0.119
2015 Najjar M, Manzoli V, Abreu M, Villa C, Martino MM, Molano D, Torrente Y, Pileggi A, Inverardi L, Ricordi C, Hubbell JA, Tomei AA. Fibrin gels engineered with pro-angiogenic growth factors promote engraftment of pancreatic islets in extrahepatic sites in mice Biotechnology and Bioengineering. DOI: 10.1002/bit.25589  0.118
2008 Ehrbar M, Rizzi SC, Schoenmakers RG, Hubbell JA, Weber FE, Lutolf MP. Smart biomolecular hydrogels formed and degraded via site-specific enzymatic reactions 8th World Biomaterials Congress 2008. 1: 506.  0.114
2008 Hubbell JA, Frey P, Barker TA, Martino M, Mochizuki M, Adelöw C, Yang L. Matrix-bound morphogens in tissue repair 8th World Biomaterials Congress 2008. 1: 26.  0.113
2023 Lauterbach AL, Wallace RP, Alpar AT, Refvik KC, Reda JW, Ishihara A, Beckman TN, Slezak AJ, Mizukami Y, Mansurov A, Gomes S, Ishihara J, Hubbell JA. Topically-applied collagen-binding serum albumin-fused interleukin-4 modulates wound microenvironment in non-healing wounds. Npj Regenerative Medicine. 8: 49. PMID 37696884 DOI: 10.1038/s41536-023-00326-y  0.111
2023 Grosso A, Lunger A, Burger MG, Briquez PS, Mai F, Hubbell JA, Schaefer DJ, Banfi A, Di Maggio N. VEGF dose controls the coupling of angiogenesis and osteogenesis in engineered bone. Npj Regenerative Medicine. 8: 15. PMID 36914692 DOI: 10.1038/s41536-023-00288-1  0.11
2011 Velluto D, Thomas S, Swartz M, Hubbell JA. Polymeric nanomaterials for gene delivery in B16f10 murine melanoma 24th European Conference On Biomaterials - Annual Conference of the European Society For Biomaterials.  0.11
1998 Hill RS, Cruise GM, Hager SR, Lamberti FV, Yu X, Garufis CL, Yu Y, Mundwiler KE, Cole JF, Hubbell JA, Hegre OD, Scharp DW. Immunoisolation of adult porcine islets for the treatment of diabetes mellitus. The use of photopolymerizable polyethylene glycol in the conformal coating of mass-isolated porcine islets. Annals of the New York Academy of Sciences. 831: 332-43. PMID 9616725 DOI: 10.1111/j.1749-6632.1997.tb52208.x  0.108
2015 Kontos S, Grimm AJ, Hubbell JA. Engineering antigen-specific immunological tolerance Current Opinion in Immunology. 35: 80-88. DOI: 10.1016/j.coi.2015.05.005  0.106
2008 Ihm JE, Lee ST, Hubbell JA. Three dimensional culture of murin ovarian follicles using PEG-hydrogel 8th World Biomaterials Congress 2008. 3: 1727.  0.106
2011 Dane KY, Nembrini C, Tomei AA, Eby JK, O'neil CP, Velluto D, Inverardi L, Swartz MA, Hubbell JA. Nano-sized drug-loaded micelles deliver payload to dendritic cells in the lymph nodes and prolong allograft survival 24th European Conference On Biomaterials - Annual Conference of the European Society For Biomaterials.  0.105
2010 Velluto D, Thomas S, Swartz M, Hubbell JA. New block copolymer nanoparticles for gene delivery European Cells and Materials. 20: 264.  0.105
2024 Hubbell JA. Immunoengineering a Future of Molecular, Material, and Cellular Therapeutics. Journal of Immunology (Baltimore, Md. : 1950). 212: 167-168. PMID 38166250 DOI: 10.4049/jimmunol.2300773  0.102
2021 Mansurov A, Lauterbach A, Budina E, Alpar AT, Hubbell JA, Ishihara J. Immunoengineering approaches for cytokine therapy. American Journal of Physiology. Cell Physiology. PMID 34232748 DOI: 10.1152/ajpcell.00515.2020  0.101
2007 Mercanzini A, Reddy S, Velluto D, Colin P, Maillard A, Bensadoun JC, Bertsch A, Hubbell JA, Renaud P. Controlled release drug coatings on flexible neural probes Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 6612-6615. DOI: 10.1109/IEMBS.2007.4353875  0.1
2023 Lauterbach AL, Wallace RP, Alpar AT, Refvik KC, Reda JW, Ishihara A, Beckman TN, Slezak AJ, Mizukami Y, Mansurov A, Gomes S, Ishihara J, Hubbell JA. Author Correction: Topically-applied collagen-binding serum albumin-fused interleukin-4 modulates wound microenvironment in non-healing wounds. Npj Regenerative Medicine. 8: 62. PMID 37919358 DOI: 10.1038/s41536-023-00338-8  0.1
2007 Ehrbar M, Lütolf MP, Rizzi SC, Hubbell JA, Weber FE. Modular enzyme-responsive biomaterials for bone tissue engineering European Cells and Materials. 14: 17.  0.099
2015 Husseini GA, Kherbeck L, Pitt WG, Hubbell JA, Christensen DA, Velluto D. Kinetics of ultrasonic drug delivery from targeted micelles Journal of Nanoscience and Nanotechnology. 15: 2099-2104. DOI: 10.1166/jnn.2015.9498  0.096
2007 Gengler M, Hall H, Hubbell JA. Reductively degradable PEG-nanoparticles for DNA delivery European Cells and Materials. 14: 119.  0.096
2015 Julier Z, Martino MM, De Titta A, Jeanbart L, Hubbell JA. The TLR4 agonist fibronectin extra domain a is cryptic, Exposed by elastase-2; Use in a fibrin matrix cancer vaccine Scientific Reports. 5. DOI: 10.1038/srep08569  0.094
1997 Hubbell JA. Engineering the Cellular-Synthetic Substrate Interface Journal of Vascular and Interventional Radiology. 8: 715-716. DOI: 10.1016/S1051-0443(97)72522-3  0.092
2008 Rothenfluh DA, Martino M, Hubbell JA. Engineering of TIMP-3 and FGF-18 targeted to collagen II in cartilage 8th World Biomaterials Congress 2008. 2: 568.  0.091
2024 Volpatti LR, de Matos SN, Borjas G, Reda J, Watkins EA, Zhou Z, Nguyen M, Solanki A, Fang Y, Hubbell JA. LDL-Binding IL-10 Reduces Vascular Inflammation in Atherosclerotic Mice. Biorxiv : the Preprint Server For Biology. PMID 38496521 DOI: 10.1101/2024.03.04.582839  0.089
2010 Vasdekis AE, Cuennet JG, Song WZ, Choi JW, De Sio L, O'Neil CP, Hubbell JA, Psaltis D. Surface optofluidics Proceedings of Spie - the International Society For Optical Engineering. 7762. DOI: 10.1117/12.860785  0.086
2008 Rizzi SC, Xie Y, Dawson R, Ehrbar M, Hubbell JA, Lutolf MP, Upton Z. Injectable biomimetic matrices to guide impaired wound healing 8th World Biomaterials Congress 2008. 1: 432.  0.085
2013 Hubbell JA. Matrix Effects Principles of Tissue Engineering: Fourth Edition. 407-421. DOI: 10.1016/B978-0-12-398358-9.00021-5  0.084
2010 Williams JM, Lin YJ, Loftus JP, Faleiros RR, Peroni JF, Hubbell JA, Ravis WR, Belknap JK. Effect of intravenous lidocaine administration on laminar inflammation in the black walnut extract model of laminitis. Equine Veterinary Journal. 42: 261-9. PMID 20486984 DOI: 10.2746/042516409X475760  0.082
2010 Hubbell JA, Swartz MA, Hirosue S, van der Vlies AJ, Velluto D, O'Neil CP, Simeoni E, Stano A, Nembrini C, Thomas SN, Kourtis I. Polymeric nanomaterials in vaccine adjuvancy European Cells and Materials. 20: 116.  0.08
2008 Hubbell JA, Swartz MA, Reddy ST, Van Der Vlies A, Simeoni E, Kourtis I, Rothenfluh DA, Velluto D, O'Neil CP. Biological and biophysical activity in nanoparticulate materials 8th World Biomaterials Congress 2008. 1: 25.  0.076
2015 Hubbell JA, Muir WW. Oxygenation, oxygen delivery and anaesthesia in the horse. Equine Veterinary Journal. 47: 25-35. PMID 24612155 DOI: 10.1111/evj.12258  0.07
2014 Zakrzewski JL, Van Den Brink MRM, Hubbell JA. Overcoming immunological barriers in regenerative medicine Nature Biotechnology. 32: 786-794. DOI: 10.1038/nbt.2960  0.069
2007 Hubbell JA, Martino M, Pullin B, Simeoni E, Mochizuki M, Jo YS. Helping bone biology with growth factors European Cells and Materials. 14: 45.  0.068
2007 Ehrbar M, Lütolf MP, Sala A, Rizzi SC, Hubbell JA, Weber FE. Enzymaticically formed, modular designed biomaterials European Cells and Materials. 14: 10.  0.065
2010 Hubbell JA, Saville WJ, Bednarski RM. The use of sedatives, analgesic and anaesthetic drugs in the horse: an electronic survey of members of the American Association of Equine Practitioners (AAEP). Equine Veterinary Journal. 42: 487-93. PMID 20716187 DOI: 10.1111/j.2042-3306.2010.00104.x  0.055
2013 Hubbell JA, Kelly EM, Aarnes TK, Bednarski RM, Lerche P, Liu Z, Lakritz J. Pharmacokinetics of midazolam after intravenous administration to horses. Equine Veterinary Journal. 45: 721-5. PMID 23489241 DOI: 10.1111/Evj.12049  0.038
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