Puneet R. Gaitonde, Ph.D. - Publications
Affiliations: | 2012 | Pharmaceutical Sciences | State University of New York, Buffalo, Buffalo, NY, United States |
Area:
Pharmacy, ImmunologyYear | Citation | Score | |||
---|---|---|---|---|---|
2014 | Gaitonde P, Purohit VS, Balu-Iyer SV. Intravenous administration of Factor VIII-O-Phospho-L-Serine (OPLS) complex reduces immunogenicity and preserves pharmacokinetics of the therapeutic protein. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 66: 157-162. PMID 25459532 DOI: 10.1016/J.Ejps.2014.10.010 | 0.729 | |||
2013 | Gaitonde P, Ramakrishnan R, Chin J, Kelleher RJ, Bankert RB, Balu-Iyer SV. Exposure to factor VIII protein in the presence of phosphatidylserine induces hypo-responsiveness toward factor VIII challenge in hemophilia A mice. The Journal of Biological Chemistry. 288: 17051-6. PMID 23649621 DOI: 10.1074/Jbc.C112.396325 | 0.729 | |||
2012 | Gaitonde P, Peng A, Straubinger RM, Bankert RB, Balu-Iyer SV. Downregulation of CD40 signal and induction of TGF-β by phosphatidylinositol mediates reduction in immunogenicity against recombinant human Factor VIII. Journal of Pharmaceutical Sciences. 101: 48-55. PMID 21953409 DOI: 10.1002/Jps.22746 | 0.743 | |||
2011 | Gaitonde P, Balu-Iyer SV. In vitro immunogenicity risk assessment of therapeutic proteins in preclinical setting. Methods in Molecular Biology (Clifton, N.J.). 716: 267-80. PMID 21318912 DOI: 10.1007/978-1-61779-012-6_16 | 0.684 | |||
2011 | Gaitonde P, Peng A, Straubinger RM, Bankert RB, Balu-Iyer SV. Phosphatidylserine reduces immune response against human recombinant Factor VIII in Hemophilia A mice by regulation of dendritic cell function. Clinical Immunology (Orlando, Fla.). 138: 135-45. PMID 21094627 DOI: 10.1016/J.Clim.2010.10.006 | 0.738 | |||
2009 | Peng A, Gaitonde P, Kosloski MP, Miclea RD, Varma P, Balu-Iyer SV. Effect of route of administration of human recombinant factor VIII on its immunogenicity in Hemophilia A mice. Journal of Pharmaceutical Sciences. 98: 4480-4. PMID 19499565 DOI: 10.1002/Jps.21765 | 0.595 | |||
2008 | Ramani K, Purohit V, Miclea R, Gaitonde P, Straubinger RM, Balu-Iyer SV. Passive transfer of polyethylene glycol to liposomal-recombinant human FVIII enhances its efficacy in a murine model for hemophilia A. Journal of Pharmaceutical Sciences. 97: 3753-64. PMID 18300296 DOI: 10.1002/Jps.21266 | 0.644 | |||
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