Kathy K. Griendling - Publications

Affiliations: 
Emory University, Atlanta, GA 
Area:
Cell Biology, Molecular Biology

197 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Park JM, Do VQ, Seo YS, Kim HJ, Nam JH, Yin MZ, Kim HJ, Kim SJ, Griendling KK, Lee MY. NADPH Oxidase 1 Mediates Acute Blood Pressure Response to Angiotensin II by Contributing to Calcium Influx in Vascular Smooth Muscle Cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 101161ATVBAHA1213172. PMID 35354309 DOI: 10.1161/ATVBAHA.121.317239  0.314
2021 Dolmatova EV, Forrester SJ, Wang K, Ou Z, Williams HC, Joseph G, Kumar S, Valdivia A, Kowalczyk AP, Qu H, Jo H, Lassègue B, Hernandes MS, Griendling KK. Endothelial Poldip2 regulates sepsis-induced lung injury via Rho pathway activation. Cardiovascular Research. PMID 34528082 DOI: 10.1093/cvr/cvab295  0.652
2020 Maheswaranathan M, Gole HKA, Fernandez I, Lassègue B, Griendling KK, San Martín A. Correction: Platelet-derived growth factor (PDGF) regulates slingshot phosphatase activity via Nox1-dependent auto-dephosphorylation of serine 834 in vascular smooth muscle cells. The Journal of Biological Chemistry. 295: 8348. PMID 32532854 DOI: 10.1074/jbc.AAC120.014380  0.323
2020 Grimsley-Myers CM, Isaacson RH, Cadwell CM, Campos J, Hernandes MS, Myers KR, Seo T, Giang W, Griendling KK, Kowalczyk AP. VE-cadherin endocytosis controls vascular integrity and patterning during development. The Journal of Cell Biology. 219. PMID 32232465 DOI: 10.1083/Jcb.201909081  0.365
2020 Dolmatova EV, Wang K, Mandavilli R, Griendling KK. The effects of sepsis on endothelium and clinical implications. Cardiovascular Research. PMID 32215570 DOI: 10.1093/Cvr/Cvaa070  0.38
2019 Kikuchi DS, Campos ACP, Qu H, Forrester SJ, Pagano RL, Lassègue B, Sadikot RT, Griendling KK, Hernandes MS. Poldip2 mediates blood-brain barrier disruption in a model of sepsis-associated encephalopathy. Journal of Neuroinflammation. 16: 241. PMID 31779628 DOI: 10.1186/S12974-019-1575-4  0.302
2019 Dolmatova EV, Griendling KK. Platelet microRNAs and vascular injury. The Journal of Clinical Investigation. 129: 962-964. PMID 30776027 DOI: 10.1172/Jci127580  0.351
2019 Huff LP, Kikuchi DS, Faidley E, Forrester SJ, Tsai MZ, Lassègue B, Griendling KK. Polymerase delta interacting protein 2 activates the RhoGEF Epithelial cell transforming sequence 2 in vascular smooth muscle cells. American Journal of Physiology. Cell Physiology. PMID 30726115 DOI: 10.1152/Ajpcell.00208.2018  0.474
2019 Forrester SJ, Xu Q, Kikuchi DS, Okwan-Duodu D, Campos AC, Faidley EA, Zhang G, Lassègue B, Sadikot RT, Griendling KK, Hernandes MS. Poldip2 Deficiency Protects Against Lung Edema and Vascular Inflammation in a Model of Acute Respiratory Distress Syndrome. Clinical Science (London, England : 1979). PMID 30622219 DOI: 10.1042/Cs20180944  0.359
2018 Li L, Lai EY, Luo Z, Solis G, Mendonca M, Griendling KK, Wellstein A, Welch WJ, Wilcox CS. High Salt Enhances Reactive Oxygen Species and Angiotensin II Contractions of Glomerular Afferent Arterioles From Mice With Reduced Renal Mass. Hypertension (Dallas, Tex. : 1979). 72: 1208-1216. PMID 30354808 DOI: 10.1161/Hypertensionaha.118.11354  0.403
2018 Vukelic S, Xu Q, Seidel-Rogol B, Faidley EA, Dikalova AE, Hilenski LL, Jorde U, Poole LB, Lassègue B, Zhang G, Griendling KK. NOX4 (NADPH Oxidase 4) and Poldip2 (Polymerase δ-Interacting Protein 2) Induce Filamentous Actin Oxidation and Promote Its Interaction With Vinculin During Integrin-Mediated Cell Adhesion. Arteriosclerosis, Thrombosis, and Vascular Biology. 38: 2423-2434. PMID 30354218 DOI: 10.1161/Atvbaha.118.311668  0.387
2018 Datla SR, L Hilenski L, Seidel-Rogol B, Dikalova AE, Harousseau M, Punkova L, Joseph G, Taylor WR, Lassègue B, Griendling KK. Poldip2 knockdown inhibits vascular smooth muscle proliferation and neointima formation by regulating the expression of PCNA and p21. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 30237457 DOI: 10.1038/S41374-018-0103-Y  0.463
2018 Paredes F, Lassègue B, Williams HC, Faidley EA, Benavides GA, Yeligar SM, Griendling KK, Darley-Usmar V, San Martin A. Reply to Bailey et al.: New perspectives on the novel role of the Poldip2/ACSM1 axis in a functional mammalian lipoylation salvage pathway. Proceedings of the National Academy of Sciences of the United States of America. PMID 30042216 DOI: 10.1073/Pnas.1807968115  0.665
2018 Forrester SJ, Kikuchi DS, Hernandes MS, Xu Q, Griendling KK. Reactive Oxygen Species in Metabolic and Inflammatory Signaling. Circulation Research. 122: 877-902. PMID 29700084 DOI: 10.1161/Circresaha.117.311401  0.358
2018 Hernandes MS, Lassègue B, Hilenski LL, Adams J, Gao N, Kuan CY, Sun YY, Cheng L, Kikuchi DS, Yepes M, Griendling KK. Polymerase delta-interacting protein 2 deficiency protects against blood-brain barrier permeability in the ischemic brain. Journal of Neuroinflammation. 15: 45. PMID 29452577 DOI: 10.1186/S12974-017-1032-1  0.33
2018 Paredes F, Sheldon K, Lassègue B, Williams HC, Faidley EA, Benavides GA, Torres G, Sanhueza-Olivares F, Yeligar SM, Griendling KK, Darley-Usmar V, San Martin A. Poldip2 is an oxygen-sensitive protein that controls PDH and αKGDH lipoylation and activation to support metabolic adaptation in hypoxia and cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 29434038 DOI: 10.1073/Pnas.1720693115  0.694
2018 FUJII M, SONODA N, OKAMOTO M, MORINAGA H, OGAWA Y, GRIENDLING K. Poldip2 Affects Collagen I Accumulation by Regulating the Expression of Zyxin in Vascular Smooth Muscle Cells Diabetes. 67: 478-P. DOI: 10.2337/db18-478-p  0.34
2018 Li L, Lai E, Luo Z, Solis G, Mendonca M, Griendling K, Wellstein A, Welch W, WILCOX CS. Abstract 051: High Salt Enhances ROS and Ang II Contractions of Glomerular Afferent Arterioles From Mice With Reduced Renal Mass Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.051  0.325
2018 Griendling K. Redox Modification of the Cytoskeleton During Cell Adhesion and Migration Free Radical Biology and Medicine. 128: S5. DOI: 10.1016/J.Freeradbiomed.2018.10.380  0.434
2018 Griendling KK. Nox4, Poldip2 and vascular function Free Radical Biology and Medicine. 120: S11-S12. DOI: 10.1016/J.Freeradbiomed.2018.04.051  0.461
2017 Caesar C, Lyle AN, Joseph G, Weiss D, Alameddine FMF, Lassègue B, Griendling KK, Taylor WR. Cyclic Strain and Hypertension Increase Osteopontin Expression in the Aorta. Cellular and Molecular Bioengineering. 10: 144-152. PMID 29552233 DOI: 10.1007/S12195-016-0475-2  0.75
2017 Xu Q, Kulkarni AA, Sajith AM, Hussein D, Brown D, Güner OF, Reddy MD, Watkins EB, Lassègue B, Griendling KK, Bowen JP. Design, synthesis, and biological evaluation of inhibitors of the NADPH oxidase, Nox4. Bioorganic & Medicinal Chemistry. PMID 29426628 DOI: 10.1016/J.Bmc.2017.12.023  0.37
2017 Forrester SJ, Griendling KK. Mitochondrial Respiration and Atherosclerosis: R-E-S-P-I-R-E. Find Out What it Means to Mϕ (and VSMC). Arteriosclerosis, Thrombosis, and Vascular Biology. 37: 2229-2230. PMID 29162598 DOI: 10.1161/Atvbaha.117.310298  0.371
2017 Hernandes MS, Lassègue B, Griendling KK. Polymerase δ-interacting Protein 2: A Multifunctional Protein. Journal of Cardiovascular Pharmacology. 69: 335-342. PMID 28574953 DOI: 10.1097/Fjc.0000000000000465  0.326
2017 Li L, Lai EY, Luo Z, Solis G, Griendling KK, Taylor WR, Jose PA, Wellsten A, Welch WJ, Wilcox CS. Superoxide and hydrogen peroxide counterregulate myogenic contractions in renal afferent arterioles from a mouse model of chronic kidney disease. Kidney International. PMID 28396118 DOI: 10.1016/J.Kint.2017.02.009  0.35
2017 Salazar G, Huang J, Feresin RG, Zhao Y, Griendling KK. Zinc Regulates Nox1 Expression Through a NF-κB and Mitochondrial ROS Dependent Mechanism to Induce Senescence of Vascular Smooth Muscle Cells. Free Radical Biology & Medicine. PMID 28363602 DOI: 10.1016/J.Freeradbiomed.2017.03.032  0.501
2017 Xu Q, Huff LP, Fujii M, Griendling KK. Redox regulation of the actin cytoskeleton and its role in the vascular system. Free Radical Biology & Medicine. PMID 28285002 DOI: 10.1016/J.Freeradbiomed.2017.03.004  0.445
2017 Amanso A, Lyle AN, Griendling KK. NADPH Oxidases and Measurement of Reactive Oxygen Species. Methods in Molecular Biology (Clifton, N.J.). 1527: 219-232. PMID 28116720 DOI: 10.1007/978-1-4939-6625-7_18  0.723
2017 Kikuchi D, Huff L, Lassegue B, Griendling K. Poldip2 Activates the Rho Guanine Nucleotide Exchange Factor Ect2 To Regulate Vascular Smooth Muscle Cell Proliferation Free Radical Biology and Medicine. 112: 115-116. DOI: 10.1016/J.Freeradbiomed.2017.10.173  0.485
2016 Katsumura S, Izu Y, Yamada T, Griendling K, Harada K, Noda M, Ezura Y. FGF Suppresses Poldip2 Expression in Osteoblasts. Journal of Cellular Biochemistry. PMID 27918072 DOI: 10.1002/Jcb.25813  0.336
2016 Di Marco E, Gray SP, Kennedy K, Szyndralewiez C, Lyle AN, Lassègue B, Griendling KK, Cooper ME, Schmidt HH, Jandeleit-Dahm KA. NOX4-derived reactive oxygen species limit fibrosis and inhibit proliferation of vascular smooth muscle cells in diabetic atherosclerosis. Free Radical Biology & Medicine. PMID 27445103 DOI: 10.1016/J.Freeradbiomed.2016.07.013  0.752
2016 Griendling KK, Touyz RM, Zweier JL, Dikalov S, Chilian W, Chen YR, Harrison DG, Bhatnagar A. Measurement of Reactive Oxygen Species, Reactive Nitrogen Species, and Redox-Dependent Signaling in the Cardiovascular System: A Scientific Statement From the American Heart Association. Circulation Research. PMID 27418630 DOI: 10.1161/Res.0000000000000110  0.322
2016 Lee M, San Martín A, Valdivia A, Martin-Garrido A, Griendling KK. Redox-Sensitive Regulation of Myocardin-Related Transcription Factor (MRTF-A) Phosphorylation via Palladin in Vascular Smooth Muscle Cell Differentiation Marker Gene Expression. Plos One. 11: e0153199. PMID 27088725 DOI: 10.1371/Journal.Pone.0153199  0.451
2016 Fujii M, Amanso A, Abrahão TB, Lassègue B, Griendling KK. Polymerase delta-interacting protein 2 regulates collagen accumulation via activation of the Akt/mTOR pathway in vascular smooth muscle cells. Journal of Molecular and Cellular Cardiology. 92: 21-9. PMID 26801741 DOI: 10.1016/J.Yjmcc.2016.01.016  0.456
2015 Fernandez I, Martin-Garrido A, Zhou DW, Clempus RE, Seidel-Rogol B, Valdivia A, Lassègue B, García AJ, Griendling KK, San Martin A. Hic-5 Mediates TGFβ-Induced Adhesion in Vascular Smooth Muscle Cells by a Nox4-Dependent Mechanism. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 1198-206. PMID 25814672 DOI: 10.1161/Atvbaha.114.305185  0.389
2015 Brown DI, Griendling KK. Regulation of signal transduction by reactive oxygen species in the cardiovascular system. Circulation Research. 116: 531-49. PMID 25634975 DOI: 10.1161/Circresaha.116.303584  0.382
2015 Abrahao TB, Griendling KK. Nuclear factor (erythroid-derived 2)-like 2, the brake in oxidative stress that nicotinamide adenine dinucleotide phosphate-oxidase-4 needs to protect the heart. Hypertension. 65: 499-501. PMID 25534706 DOI: 10.1161/Hypertensionaha.114.04347  0.409
2014 Datla SR, McGrail DJ, Vukelic S, Huff LP, Lyle AN, Pounkova L, Lee M, Seidel-Rogol B, Khalil MK, Hilenski LL, Terada LS, Dawson MR, Lassègue B, Griendling KK. Poldip2 controls vascular smooth muscle cell migration by regulating focal adhesion turnover and force polarization. American Journal of Physiology. Heart and Circulatory Physiology. 307: H945-57. PMID 25063792 DOI: 10.1152/Ajpheart.00918.2013  0.74
2014 Manickam N, Patel M, Griendling KK, Gorin Y, Barnes JL. RhoA/Rho kinase mediates TGF-β1-induced kidney myofibroblast activation through Poldip2/Nox4-derived reactive oxygen species. American Journal of Physiology. Renal Physiology. 307: F159-71. PMID 24872317 DOI: 10.1152/Ajprenal.00546.2013  0.391
2014 Amanso AM, Lassègue B, Joseph G, Landázuri N, Long JS, Weiss D, Taylor WR, Griendling KK. Polymerase δ-interacting protein 2 promotes postischemic neovascularization of the mouse hindlimb. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 1548-55. PMID 24855063 DOI: 10.1161/Atvbaha.114.303873  0.443
2014 Brown DI, Lassègue B, Lee M, Zafari R, Long JS, Saavedra HI, Griendling KK. Poldip2 knockout results in perinatal lethality, reduced cellular growth and increased autophagy of mouse embryonic fibroblasts. Plos One. 9: e96657. PMID 24797518 DOI: 10.1371/Journal.Pone.0096657  0.357
2014 Vukelic S, Griendling KK. Angiotensin II, from vasoconstrictor to growth factor: a paradigm shift. Circulation Research. 114: 754-7. PMID 24577962 DOI: 10.1161/Circresaha.114.303045  0.384
2014 Ushio-Fukai M, Griendling KK, Becker PL, Hilenski L, Halleran S, Alexander RW. Notice of retraction. Epidermal growth factor receptor transactivation by angiotensin II requires reactive oxygen species in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 2001;21:489-95. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: e2. PMID 24368572 DOI: 10.1161/01.Atv.0000441331.18233.7C  0.447
2014 Lyle AN, Remus EW, Fan AE, Lassègue B, Walter GA, Kiyosue A, Griendling KK, Taylor WR. Hydrogen peroxide regulates osteopontin expression through activation of transcriptional and translational pathways. The Journal of Biological Chemistry. 289: 275-85. PMID 24247243 DOI: 10.1074/Jbc.M113.489641  0.723
2014 Dikalov SI, Nazarewicz RR, Bikineyeva A, Hilenski L, Lassègue B, Griendling KK, Harrison DG, Dikalova AE. Nox2-induced production of mitochondrial superoxide in angiotensin II-mediated endothelial oxidative stress and hypertension. Antioxidants & Redox Signaling. 20: 281-94. PMID 24053613 DOI: 10.1089/Ars.2012.4918  0.43
2013 Martin-Garrido A, Williams HC, Lee M, Seidel-Rogol B, Ci X, Dong JT, Lassègue B, Martín AS, Griendling KK. Transforming growth factor β inhibits platelet derived growth factor-induced vascular smooth muscle cell proliferation via Akt-independent, Smad-mediated cyclin D1 downregulation. Plos One. 8: e79657. PMID 24236150 DOI: 10.1371/Journal.Pone.0079657  0.724
2013 Ushio-Fukai M, Hilenski L, Santanam N, Becker PL, Ma Y, Griendling KK, Alexander RW. Cholesterol depletion inhibits epidermal growth factor receptor transactivation by angiotensin II in vascular smooth muscle cells. Role of cholesterol-rich microdomains and focal adhesions in angiotensin II signaling. The Journal of Biological Chemistry. 288: 32637. PMID 24215069 DOI: 10.1074/Jbc.A113.105901  0.427
2013 Sutliff RL, Hilenski LL, Amanso AM, Parastatidis I, Dikalova AE, Hansen L, Datla SR, Long JS, El-Ali AM, Joseph G, Gleason RL, Taylor WR, Hart CM, Griendling KK, Lassègue B. Polymerase delta interacting protein 2 sustains vascular structure and function. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 2154-61. PMID 23825363 DOI: 10.1161/Atvbaha.113.301913  0.475
2013 Koga M, Engberding N, Dikalova AE, Chang KH, Seidel-Rogol B, Long JS, Lassègue B, Jo H, Griendling KK. The bone morphogenic protein inhibitor, noggin, reduces glycemia and vascular inflammation in db/db mice. American Journal of Physiology. Heart and Circulatory Physiology. 305: H747-55. PMID 23812391 DOI: 10.1152/Ajpheart.00825.2012  0.408
2013 Kim CW, Song H, Kumar S, Nam D, Kwon HS, Chang KH, Son DJ, Kang DW, Brodie SA, Weiss D, Vega JD, Alberts-Grill N, Griendling K, Taylor WR, Jo H. Anti-inflammatory and antiatherogenic role of BMP receptor II in endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 1350-9. PMID 23559633 DOI: 10.1161/Atvbaha.112.300287  0.405
2013 Fernandez I, Martin-Garrido A, Clempus RE, Seidel-Rogol B, Amanso A, Lassegue B, Griendling KK, San Martin A. TGF-β Mediates Focal Adhesion Maturation by a Smad/Nox4-Dependent Mechanism that Involves Regulation of Hsp27 and Hic5 Free Radical Biology and Medicine. 65: S157-S158. DOI: 10.1016/J.Freeradbiomed.2013.10.792  0.308
2013 Duran C, Williams HC, Lassegue B, Griendling KK, San Martin A. Role of βPIX in PDGF-Induced Lamellipodia Dynamics in VSMC Free Radical Biology and Medicine. 65: S157. DOI: 10.1016/J.Freeradbiomed.2013.10.791  0.673
2012 Williams HC, San Martín A, Adamo CM, Seidel-Rogol B, Pounkova L, Datla SR, Lassègue B, Bear JE, Griendling K. Role of coronin 1B in PDGF-induced migration of vascular smooth muscle cells. Circulation Research. 111: 56-65. PMID 22619279 DOI: 10.1161/Circresaha.111.255745  0.747
2012 Lassègue B, San Martín A, Griendling KK. Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system. Circulation Research. 110: 1364-90. PMID 22581922 DOI: 10.1161/Circresaha.111.243972  0.418
2012 Lai EY, Luo Z, Onozato ML, Rudolph EH, Solis G, Jose PA, Wellstein A, Aslam S, Quinn MT, Griendling K, Le T, Li P, Palm F, Welch WJ, Wilcox CS. Effects of the antioxidant drug tempol on renal oxygenation in mice with reduced renal mass. American Journal of Physiology. Renal Physiology. 303: F64-74. PMID 22492941 DOI: 10.1152/Ajprenal.00005.2012  0.326
2012 Xu S, Shriver AS, Jagadeesha DK, Chamseddine AH, Sz?cs K, Weintraub NL, Griendling KK, Bhalla RC, Miller FJ. Increased expression of Nox1 in neointimal smooth muscle cells promotes activation of matrix metalloproteinase-9. Journal of Vascular Research. 49: 242-8. PMID 22433789 DOI: 10.1159/000332958  0.421
2012 Amanso AM, Griendling KK. Differential roles of NADPH oxidases in vascular physiology and pathophysiology. Frontiers in Bioscience (Scholar Edition). 4: 1044-64. PMID 22202108 DOI: 10.2741/S317  0.492
2012 Griendling KK, Ushio-Fukai M. NADH/NADPH Oxidase and Vascular Function. Trends in Cardiovascular Medicine. 7: 301-7. PMID 21235900 DOI: 10.1016/S1050-1738(97)00088-1  0.471
2012 Griendling K. NADPH Oxidases as Mediators of Vascular Physiology Free Radical Biology and Medicine. 53: S3. DOI: 10.1016/J.Freeradbiomed.2012.08.074  0.43
2012 Martín AS, Hilenski L, Griendling KK. Molecular Pathways of Smooth Muscle Disease Musclefundamental Biology and Mechanisms of Disease. 1279-1287. DOI: 10.1016/B978-0-12-381510-1.00096-X  0.425
2011 Hitomi H, Mehta PK, Taniyama Y, Lassègue B, Seidel-Rogol B, San Martin A, Griendling KK. Vascular smooth muscle insulin resistance, but not hypertrophic signaling, is independent of angiotensin II-induced IRS-1 phosphorylation by JNK. American Journal of Physiology. Cell Physiology. 301: C1415-22. PMID 21900690 DOI: 10.1152/Ajpcell.00017.2011  0.379
2011 Maheswaranathan M, Gole HK, Fernandez I, Lassègue B, Griendling KK, San Martín A. Platelet-derived growth factor (PDGF) regulates Slingshot phosphatase activity via Nox1-dependent auto-dephosphorylation of serine 834 in vascular smooth muscle cells. The Journal of Biological Chemistry. 286: 35430-7. PMID 21857021 DOI: 10.1074/Jbc.M111.268284  0.499
2011 Liu G, Hitomi H, Hosomi N, Lei B, Nakano D, Deguchi K, Mori H, Masaki T, Ma H, Griendling KK, Nishiyama A. Mechanical stretch augments insulin-induced vascular smooth muscle cell proliferation by insulin-like growth factor-1 receptor. Experimental Cell Research. 317: 2420-8. PMID 21854769 DOI: 10.1016/J.Yexcr.2011.07.016  0.325
2011 Al Ghouleh I, Khoo NKH, Knaus UG, Griendling KK, Touyz RM, Thannickal VJ, Barchowsky A, Nauseef WM, Kelley EE, Bauer PM, Darley-Usmar V, Shiva S, Cifuentes-Pagano E, Freeman BA, Gladwin MT, et al. Oxidases and peroxidases in cardiovascular and lung disease: New concepts in reactive oxygen species signaling Free Radical Biology and Medicine. 51: 1271-1288. PMID 21722728 DOI: 10.1016/J.Freeradbiomed.2011.06.011  0.409
2011 Drummond GR, Selemidis S, Griendling KK, Sobey CG. Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets. Nature Reviews. Drug Discovery. 10: 453-71. PMID 21629295 DOI: 10.1038/Nrd3403  0.425
2011 Martin-Garrido A, Brown DI, Lyle AN, Dikalova A, Seidel-Rogol B, Lassègue B, San Martín A, Griendling KK. NADPH oxidase 4 mediates TGF-β-induced smooth muscle α-actin via p38MAPK and serum response factor. Free Radical Biology & Medicine. 50: 354-62. PMID 21074607 DOI: 10.1016/J.Freeradbiomed.2010.11.007  0.726
2010 Luo Z, Teerlink T, Griendling K, Aslam S, Welch WJ, Wilcox CS. Angiotensin II and NADPH oxidase increase ADMA in vascular smooth muscle cells. Hypertension. 56: 498-504. PMID 20696982 DOI: 10.1161/Hypertensionaha.110.152959  0.472
2010 Datla SR, Griendling KK. Reactive oxygen species, NADPH oxidases, and hypertension. Hypertension. 56: 325-30. PMID 20644010 DOI: 10.1161/Hypertensionaha.109.142422  0.41
2010 Dikalova AE, Góngora MC, Harrison DG, Lambeth JD, Dikalov S, Griendling KK. Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncoupling. American Journal of Physiology. Heart and Circulatory Physiology. 299: H673-9. PMID 20639222 DOI: 10.1152/Ajpheart.00242.2010  0.446
2010 Lassègue B, Griendling KK. NADPH oxidases: functions and pathologies in the vasculature. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 653-61. PMID 19910640 DOI: 10.1161/Atvbaha.108.181610  0.449
2010 San Martín A, Griendling KK. Redox control of vascular smooth muscle migration. Antioxidants & Redox Signaling. 12: 625-40. PMID 19737088 DOI: 10.1089/Ars.2009.2852  0.488
2010 Dikalova A, Góngora MC, Harrison D, Lambeth D, Dikalov S, Griendling K. Supplementation with Tetrahydrobiopterin Reverse Impaired Endothelium-Dependent Relaxation and eNOS Uncoupling Induced by Nox1 Overexpression in Vascular Smooth Muscle Free Radical Biology and Medicine. 49: S180. DOI: 10.1016/J.Freeradbiomed.2010.10.512  0.443
2010 Dikalov S, Dikalova A, Nazarewicz R, Bikineyeva A, Mayorov V, Hilenski L, Lassègue B, Harrison D, Griendling K. Role of Nox2-induced Reverse Electron Transfer in Production of Mitochondrial Reactive Oxygen Species, Endothelial Dysfunction and Hypertension Free Radical Biology and Medicine. 49: S20. DOI: 10.1016/J.Freeradbiomed.2010.10.021  0.384
2009 Brown DI, Griendling KK. Nox proteins in signal transduction. Free Radical Biology & Medicine. 47: 1239-53. PMID 19628035 DOI: 10.1016/J.Freeradbiomed.2009.07.023  0.397
2009 Martín-Garrido A, Boyano-Adánez MC, Alique M, Calleros L, Serrano I, Griera M, Rodríguez-Puyol D, Griendling KK, Rodríguez-Puyol M. Hydrogen peroxide down-regulates inositol 1,4,5-trisphosphate receptor content through proteasome activation. Free Radical Biology & Medicine. 47: 1362-70. PMID 19596064 DOI: 10.1016/J.Freeradbiomed.2009.07.006  0.355
2009 Lyle AN, Deshpande NN, Taniyama Y, Seidel-Rogol B, Pounkova L, Du P, Papaharalambus C, Lassègue B, Griendling KK. Poldip2, a novel regulator of Nox4 and cytoskeletal integrity in vascular smooth muscle cells. Circulation Research. 105: 249-59. PMID 19574552 DOI: 10.1161/Circresaha.109.193722  0.756
2009 Guzik TJ, Griendling KK. NADPH oxidases: molecular understanding finally reaching the clinical level? Antioxidants & Redox Signaling. 11: 2365-70. PMID 19358633 DOI: 10.1089/Ars.2009.2615  0.396
2009 Lee MY, San Martin A, Mehta PK, Dikalova AE, Garrido AM, Datla SR, Lyons E, Krause KH, Banfi B, Lambeth JD, Lassègue B, Griendling KK. Mechanisms of vascular smooth muscle NADPH oxidase 1 (Nox1) contribution to injury-induced neointimal formation. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 480-7. PMID 19150879 DOI: 10.1161/Atvbaha.108.181925  0.466
2009 Garrido AM, Griendling KK. NADPH oxidases and angiotensin II receptor signaling. Molecular and Cellular Endocrinology. 302: 148-58. PMID 19059306 DOI: 10.1016/J.Mce.2008.11.003  0.384
2008 Dikalov SI, Dikalova AE, Bikineyeva AT, Schmidt HH, Harrison DG, Griendling KK. Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production. Free Radical Biology & Medicine. 45: 1340-51. PMID 18760347 DOI: 10.1016/J.Freeradbiomed.2008.08.013  0.396
2008 Block K, Eid A, Griendling KK, Lee DY, Wittrant Y, Gorin Y. Nox4 NAD(P)H oxidase mediates Src-dependent tyrosine phosphorylation of PDK-1 in response to angiotensin II: role in mesangial cell hypertrophy and fibronectin expression. The Journal of Biological Chemistry. 283: 24061-76. PMID 18559349 DOI: 10.1074/Jbc.M803964200  0.422
2008 Jay DB, Papaharalambus CA, Seidel-Rogol B, Dikalova AE, Lassègue B, Griendling KK. Nox5 mediates PDGF-induced proliferation in human aortic smooth muscle cells. Free Radical Biology & Medicine. 45: 329-35. PMID 18466778 DOI: 10.1016/J.Freeradbiomed.2008.04.024  0.498
2008 Lee MY, Griendling KK. Redox signaling, vascular function, and hypertension. Antioxidants & Redox Signaling. 10: 1045-59. PMID 18321201 DOI: 10.1089/Ars.2007.1986  0.494
2008 San Martín A, Lee MY, Williams HC, Mizuno K, Lassègue B, Griendling KK. Dual regulation of cofilin activity by LIM kinase and Slingshot-1L phosphatase controls platelet-derived growth factor-induced migration of human aortic smooth muscle cells. Circulation Research. 102: 432-8. PMID 18096821 DOI: 10.1161/Circresaha.107.158923  0.734
2007 Cai H, Dikalov S, Griendling KK, Harrison DG. Detection of reactive oxygen species and nitric oxide in vascular cells and tissues: comparison of sensitivity and specificity. Methods in Molecular Medicine. 139: 293-311. PMID 18287681 DOI: 10.1007/978-1-59745-571-8_20  0.418
2007 Williams HC, Griendling KK. NADPH oxidase inhibitors: new antihypertensive agents? Journal of Cardiovascular Pharmacology. 50: 9-16. PMID 17666910 DOI: 10.1097/Fjc.0B013E318063E820  0.701
2007 San Martin A, Foncea R, Laurindo FR, Ebensperger R, Griendling KK, Leighton F. Nox1-based NADPH oxidase-derived superoxide is required for VSMC activation by advanced glycation end-products. Free Radical Biology & Medicine. 42: 1671-9. PMID 17462535 DOI: 10.1016/J.Freeradbiomed.2007.02.002  0.422
2007 Govindarajan B, Sligh JE, Vincent BJ, Li M, Canter JA, Nickoloff BJ, Rodenburg RJ, Smeitink JA, Oberley L, Zhang Y, Slingerland J, Arnold RS, Lambeth JD, Cohen C, Hilenski L, ... Griendling K, et al. Overexpression of Akt converts radial growth melanoma to vertical growth melanoma. The Journal of Clinical Investigation. 117: 719-29. PMID 17318262 DOI: 10.1172/Jci30102  0.347
2007 Dikalov S, Griendling KK, Harrison DG. Measurement of reactive oxygen species in cardiovascular studies. Hypertension. 49: 717-27. PMID 17296874 DOI: 10.1161/01.Hyp.0000258594.87211.6B  0.383
2007 Papaharalambus CA, Griendling KK. Basic mechanisms of oxidative stress and reactive oxygen species in cardiovascular injury. Trends in Cardiovascular Medicine. 17: 48-54. PMID 17292046 DOI: 10.1016/J.Tcm.2006.11.005  0.437
2007 Widder JD, Guzik TJ, Mueller CF, Clempus RE, Schmidt HH, Dikalov SI, Griendling KK, Jones DP, Harrison DG. Role of the multidrug resistance protein-1 in hypertension and vascular dysfunction caused by angiotensin II. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 762-8. PMID 17272743 DOI: 10.1161/01.Atv.0000259298.11129.A2  0.41
2007 San Martín A, Du P, Dikalova A, Lassègue B, Aleman M, Góngora MC, Brown K, Joseph G, Harrison DG, Taylor WR, Jo H, Griendling KK. Reactive oxygen species-selective regulation of aortic inflammatory gene expression in Type 2 diabetes. American Journal of Physiology. Heart and Circulatory Physiology. 292: H2073-82. PMID 17237245 DOI: 10.1152/Ajpheart.00943.2006  0.412
2007 Doran DE, Weiss D, Zhang Y, Griendling KK, Taylor WR. Differential effects of AT1 receptor and Ca2+ channel blockade on atherosclerosis, inflammatory gene expression, and production of reactive oxygen species. Atherosclerosis. 195: 39-47. PMID 17224157 DOI: 10.1016/J.Atherosclerosis.2006.11.030  0.362
2007 Lassègue B, Griendling KK. Mycophenolic acid is a new Nox2 inhibitor. Hypertension. 49: 25-6. PMID 17101843 DOI: 10.1161/01.Hyp.0000251161.93696.D0  0.415
2007 Clempus RE, Sorescu D, Dikalova AE, Pounkova L, Jo P, Sorescu GP, Schmidt HH, Lassègue B, Griendling KK. Nox4 is required for maintenance of the differentiated vascular smooth muscle cell phenotype. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 42-8. PMID 17082491 DOI: 10.1161/01.Atv.0000251500.94478.18  0.454
2007 Mehta PK, Griendling KK. Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. American Journal of Physiology. Cell Physiology. 292: C82-97. PMID 16870827 DOI: 10.1152/Ajpcell.00287.2006  0.471
2006 Griendling KK. NADPH oxidases: new regulators of old functions. Antioxidants & Redox Signaling. 8: 1443-5. PMID 16987001 DOI: 10.1089/Ars.2006.8.1443  0.437
2006 Lyle AN, Griendling KK. Modulation of vascular smooth muscle signaling by reactive oxygen species. Physiology (Bethesda, Md.). 21: 269-80. PMID 16868316 DOI: 10.1152/Physiol.00004.2006  0.751
2006 Lassègue B, Griendling KK. Nox is playing with a full deck in vascular smooth muscle, a commentary on "Noxa1 is a central component of the smooth muscle NADPH oxidase in mice". Free Radical Biology & Medicine. 41: 185-7. PMID 16814096 DOI: 10.1016/J.Freeradbiomed.2006.04.024  0.393
2006 Clempus RE, Griendling KK. Reactive oxygen species signaling in vascular smooth muscle cells. Cardiovascular Research. 71: 216-25. PMID 16616906 DOI: 10.1016/J.Cardiores.2006.02.033  0.48
2006 Modlinger P, Chabrashvili T, Gill PS, Mendonca M, Harrison DG, Griendling KK, Li M, Raggio J, Wellstein A, Chen Y, Welch WJ, Wilcox CS. RNA silencing in vivo reveals role of p22phox in rat angiotensin slow pressor response. Hypertension. 47: 238-44. PMID 16391171 DOI: 10.1161/01.Hyp.0000200023.02195.73  0.412
2005 Dikalova A, Clempus R, Lassègue B, Cheng G, McCoy J, Dikalov S, San Martin A, Lyle A, Weber DS, Weiss D, Taylor WR, Schmidt HH, Owens GK, Lambeth JD, Griendling KK. Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice. Circulation. 112: 2668-76. PMID 16230485 DOI: 10.1161/Circulationaha.105.538934  0.758
2005 Zhang Y, Griendling KK, Dikalova A, Owens GK, Taylor WR. Vascular hypertrophy in angiotensin II-induced hypertension is mediated by vascular smooth muscle cell-derived H2O2. Hypertension. 46: 732-7. PMID 16172434 DOI: 10.1161/01.Hyp.0000182660.74266.6D  0.49
2005 Wendt MC, Daiber A, Kleschyov AL, Mülsch A, Sydow K, Schulz E, Chen K, Keaney JF, Lassègue B, Walter U, Griendling KK, Münzel T. Differential effects of diabetes on the expression of the gp91phox homologues nox1 and nox4. Free Radical Biology & Medicine. 39: 381-91. PMID 15993337 DOI: 10.1016/J.Freeradbiomed.2005.03.020  0.39
2005 Haider UGB, Roos TU, Kontaridis MI, Neel BG, Sorescu D, Griendling KK, Vollmar AM, Dirsch VM. Resveratrol inhibits angiotensin II- and epidermal growth factor-mediated Akt activation: Role of Gab1 and Shp2 Molecular Pharmacology. 68: 41-48. PMID 15849355 DOI: 10.1124/Mol.104.005421  0.433
2005 Taniyama Y, Hitomi H, Shah A, Alexander RW, Griendling KK. Mechanisms of reactive oxygen species-dependent downregulation of insulin receptor substrate-1 by angiotensin II. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 1142-7. PMID 15802620 DOI: 10.1161/01.Atv.0000164313.17167.Df  0.401
2005 Griendling KK. ATVB in focus: redox mechanisms in blood vessels. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 272-3. PMID 15681307 DOI: 10.1161/01.Atv.0000153515.72375.3B  0.475
2005 Hwang J, Kleinhenz DJ, Lassègue B, Griendling KK, Dikalov S, Hart CM. Peroxisome proliferator-activated receptor-γ ligands regulate endothelial membrane superoxide production American Journal of Physiology - Cell Physiology. 288: C899-C905. PMID 15590897 DOI: 10.1152/Ajpcell.00474.2004  0.395
2005 Laude K, Cai H, Fink B, Hoch N, Weber DS, McCann L, Kojda G, Fukai T, Schmidt HH, Dikalov S, Ramasamy S, Gamez G, Griendling KK, Harrison DG. Hemodynamic and biochemical adaptations to vascular smooth muscle overexpression of p22phox in mice. American Journal of Physiology. Heart and Circulatory Physiology. 288: H7-12. PMID 15471976 DOI: 10.1152/Ajpheart.00637.2004  0.452
2005 Weber DS, Rocic P, Mellis AM, Laude K, Lyle AN, Harrison DG, Griendling KK. Angiotensin II-induced hypertrophy is potentiated in mice overexpressing p22phox in vascular smooth muscle. American Journal of Physiology. Heart and Circulatory Physiology. 288: H37-42. PMID 15345488 DOI: 10.1152/Ajpheart.00638.2004  0.744
2005 Laude K, Cai H, Fink B, Hoch N, Weber DS, McCann L, Kojda G, Fukai T, Schmidt HHW, Dikalov S, Ramasamy S, Gamez G, Griendling KK, Harrison DG. Erratum: Hemodynamic and biochemical adaptations to vascular smooth muscle overexpression and p22phox in mice (American Journal of Physiology - Heart and Circulatory Physiology (January 2005) 288 (H7-H12)) American Journal of Physiology-Heart and Circulatory Physiology. 288. DOI: 10.1152/Ajpheart.0096.2005  0.359
2004 Hanna IR, Hilenski LL, Dikalova A, Taniyama Y, Dikalov S, Lyle A, Quinn MT, Lassègue B, Griendling KK. Functional association of nox1 with p22phox in vascular smooth muscle cells. Free Radical Biology & Medicine. 37: 1542-9. PMID 15477006 DOI: 10.1016/J.Freeradbiomed.2004.08.011  0.754
2004 Sorescu GP, Song H, Tressel SL, Hwang J, Dikalov S, Smith DA, Boyd NL, Platt MO, Lassègue B, Griendling KK, Jo H. Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress induces monocyte adhesion by stimulating reactive oxygen species production from a nox1-based NADPH oxidase. Circulation Research. 95: 773-9. PMID 15388638 DOI: 10.1161/01.Res.0000145728.22878.45  0.447
2004 Lassègue B, Griendling KK. Reactive oxygen species in hypertension; An update. American Journal of Hypertension. 17: 852-60. PMID 15363831 DOI: 10.1016/J.Amjhyper.2004.02.004  0.433
2004 Ambasta RK, Kumar P, Griendling KK, Schmidt HH, Busse R, Brandes RP. Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase. The Journal of Biological Chemistry. 279: 45935-41. PMID 15322091 DOI: 10.1074/Jbc.M406486200  0.385
2004 Son SM, Whalin MK, Harrison DG, Taylor WR, Griendling KK. Oxidative stress and diabetic vascular complications. Current Diabetes Reports. 4: 247-52. PMID 15265465 DOI: 10.1007/S11892-004-0075-8  0.41
2004 Taniyama Y, Ushio-Fukai M, Hitomi H, Rocic P, Kingsley MJ, Pfahnl C, Weber DS, Alexander RW, Griendling KK. Role of p38 MAPK and MAPKAPK-2 in angiotensin II-induced Akt activation in vascular smooth muscle cells. American Journal of Physiology. Cell Physiology. 287: C494-9. PMID 15084475 DOI: 10.1152/Ajpcell.00439.2003  0.437
2004 Weber DS, Taniyama Y, Rocic P, Seshiah PN, Dechert MA, Gerthoffer WT, Griendling KK. Phosphoinositide-dependent kinase 1 and p21-activated protein kinase mediate reactive oxygen species-dependent regulation of platelet-derived growth factor-induced smooth muscle cell migration. Circulation Research. 94: 1219-26. PMID 15059930 DOI: 10.1161/01.Res.0000126848.54740.4A  0.492
2004 Hilenski LL, Clempus RE, Quinn MT, Lambeth JD, Griendling KK. Distinct subcellular localizations of Nox1 and Nox4 in vascular smooth muscle cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 677-83. PMID 14670934 DOI: 10.1161/01.Atv.0000112024.13727.2C  0.477
2003 Hwang J, Ing MH, Salazar A, Lassègue B, Griendling K, Navab M, Sevanian A, Hsiai TK. Pulsatile versus oscillatory shear stress regulates NADPH oxidase subunit expression: implication for native LDL oxidation. Circulation Research. 93: 1225-32. PMID 14593003 DOI: 10.1161/01.Res.0000104087.29395.66  0.347
2003 Suzuki YJ, Griendling KK. Redox control of growth factor signaling in heart, lung, and circulation. Antioxidants & Redox Signaling. 5: 689-90. PMID 14588140 DOI: 10.1089/152308603770379973  0.445
2003 Taniyama Y, Weber DS, Rocic P, Hilenski L, Akers ML, Park J, Hemmings BA, Alexander RW, Griendling KK. Pyk2- and Src-dependent tyrosine phosphorylation of PDK1 regulates focal adhesions. Molecular and Cellular Biology. 23: 8019-29. PMID 14585963 DOI: 10.1128/Mcb.23.22.8019-8029.2003  0.398
2003 Griendling KK, FitzGerald GA. Oxidative stress and cardiovascular injury: Part II: animal and human studies. Circulation. 108: 2034-40. PMID 14581381 DOI: 10.1161/01.Cir.0000093661.90582.C4  0.381
2003 Taniyama Y, Griendling KK. Reactive oxygen species in the vasculature: molecular and cellular mechanisms. Hypertension. 42: 1075-81. PMID 14581295 DOI: 10.1161/01.Hyp.0000100443.09293.4F  0.477
2003 Griendling KK, FitzGerald GA. Oxidative stress and cardiovascular injury: Part I: basic mechanisms and in vivo monitoring of ROS. Circulation. 108: 1912-6. PMID 14568884 DOI: 10.1161/01.Cir.0000093660.86242.Bb  0.473
2003 Cai H, Griendling KK, Harrison DG. The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases. Trends in Pharmacological Sciences. 24: 471-8. PMID 12967772 DOI: 10.1016/S0165-6147(03)00233-5  0.439
2003 Hwang J, Saha A, Boo YC, Sorescu GP, McNally JS, Holland SM, Dikalov S, Giddens DP, Griendling KK, Harrison DG, Jo H. Oscillatory shear stress stimulates endothelial production of O2- from p47phox-dependent NAD(P)H oxidases, leading to monocyte adhesion. The Journal of Biological Chemistry. 278: 47291-8. PMID 12958309 DOI: 10.1074/Jbc.M305150200  0.371
2003 Weber DS, Griendling KK. The yin/yang of superoxide dismutase mimetics: potential cardiovascular therapies? British Journal of Pharmacology. 139: 1059-60. PMID 12871823 DOI: 10.1038/Sj.Bjp.0705353  0.415
2003 Rocic P, Seshiah P, Griendling KK. Reactive oxygen species sensitivity of angiotensin II-dependent translation initiation in vascular smooth muscle cells. The Journal of Biological Chemistry. 278: 36973-9. PMID 12860993 DOI: 10.1074/Jbc.M302099200  0.488
2003 Harrison DG, Cai H, Landmesser U, Griendling KK. Interactions of angiotensin II with NAD(P)H oxidase, oxidant stress and cardiovascular disease. Journal of the Renin-Angiotensin-Aldosterone System : Jraas. 4: 51-61. PMID 12806586 DOI: 10.3317/Jraas.2003.014  0.47
2003 Fries DM, Paxinou E, Themistocleous M, Swanberg E, Griendling KK, Salvemini D, Slot JW, Heijnen HF, Hazen SL, Ischiropoulos H. Expression of inducible nitric-oxide synthase and intracellular protein tyrosine nitration in vascular smooth muscle cells: role of reactive oxygen species. The Journal of Biological Chemistry. 278: 22901-7. PMID 12690103 DOI: 10.1074/Jbc.M210806200  0.448
2003 Goubaeva F, Ghosh M, Malik S, Yang J, Hinkle PM, Griendling KK, Neubig RR, Smrcka AV. Stimulation of cellular signaling and G protein subunit dissociation by G protein betagamma subunit-binding peptides. The Journal of Biological Chemistry. 278: 19634-41. PMID 12649269 DOI: 10.1074/Jbc.M300052200  0.305
2003 Harrison D, Griendling KK, Landmesser U, Hornig B, Drexler H. Role of oxidative stress in atherosclerosis. The American Journal of Cardiology. 91: 7A-11A. PMID 12645638 DOI: 10.1016/S0002-9149(02)03144-2  0.465
2003 Haider UG, Sorescu D, Griendling KK, Vollmar AM, Dirsch VM. Resveratrol increases serine15-phosphorylated but transcriptionally impaired p53 and induces a reversible DNA replication block in serum-activated vascular smooth muscle cells. Molecular Pharmacology. 63: 925-32. PMID 12644594 DOI: 10.1124/Mol.63.4.925  0.418
2002 Hanna IR, Taniyama Y, Szöcs K, Rocic P, Griendling KK. NAD(P)H oxidase-derived reactive oxygen species as mediators of angiotensin II signaling. Antioxidants & Redox Signaling. 4: 899-914. PMID 12573139 DOI: 10.1089/152308602762197443  0.464
2002 Deshpande NN, Sorescu D, Seshiah P, Ushio-Fukai M, Akers M, Yin Q, Griendling KK. Mechanism of hydrogen peroxide-induced cell cycle arrest in vascular smooth muscle. Antioxidants & Redox Signaling. 4: 845-54. PMID 12470513 DOI: 10.1089/152308602760599007  0.367
2002 Haider UG, Sorescu D, Griendling KK, Vollmar AM, Dirsch VM. Resveratrol suppresses angiotensin II-induced Akt/protein kinase B and p70 S6 kinase phosphorylation and subsequent hypertrophy in rat aortic smooth muscle cells. Molecular Pharmacology. 62: 772-7. PMID 12237323 DOI: 10.1124/Mol.62.4.772  0.425
2002 Seshiah PN, Weber DS, Rocic P, Valppu L, Taniyama Y, Griendling KK. Angiotensin II stimulation of NAD(P)H oxidase activity: upstream mediators. Circulation Research. 91: 406-13. PMID 12215489 DOI: 10.1161/01.Res.0000033523.08033.16  0.449
2002 Sorescu D, Griendling KK. Reactive oxygen species, mitochondria, and NAD(P)H oxidases in the development and progression of heart failure. Congestive Heart Failure (Greenwich, Conn.). 8: 132-40. PMID 12045381 DOI: 10.1111/J.1527-5299.2002.00717.X  0.339
2002 Sorescu D, Weiss D, Lassègue B, Clempus RE, Szöcs K, Sorescu GP, Valppu L, Quinn MT, Lambeth JD, Vega JD, Taylor WR, Griendling KK. Superoxide production and expression of nox family proteins in human atherosclerosis. Circulation. 105: 1429-35. PMID 11914250 DOI: 10.1161/01.Cir.0000012917.74432.66  0.328
2002 Mollnau H, Wendt M, Szöcs K, Lassègue B, Schulz E, Oelze M, Li H, Bodenschatz M, August M, Kleschyov AL, Tsilimingas N, Walter U, Förstermann U, Meinertz T, Griendling K, et al. Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling. Circulation Research. 90: E58-65. PMID 11884382 DOI: 10.1161/01.Res.0000012569.55432.02  0.468
2002 Lassègue B, Griendling KK. Out phoxing the endothelium: what's left without p47? Circulation Research. 90: 123-4. PMID 11834702 DOI: 10.1161/Res.90.2.123  0.405
2002 Szöcs K, Lassègue B, Sorescu D, Hilenski LL, Valppu L, Couse TL, Wilcox JN, Quinn MT, Lambeth JD, Griendling KK. Upregulation of Nox-based NAD(P)H oxidases in restenosis after carotid injury. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 21-7. PMID 11788456 DOI: 10.1161/Hq0102.102189  0.387
2002 Sorescu D, Szöcs K, Griendling KK. NAD(P)H oxidases and their relevance to atherosclerosis. Trends in Cardiovascular Medicine. 11: 124-31. PMID 11686001 DOI: 10.1016/S1050-1738(01)00097-4  0.422
2001 Griendling KK, Harrison DG. Out, damned dot: studies of the NADPH oxidase in atherosclerosis. The Journal of Clinical Investigation. 108: 1423-4. PMID 11714732 DOI: 10.1172/Jci14453  0.392
2001 Ushio-Fukai M, Hilenski L, Santanam N, Becker PL, Ma Y, Griendling KK, Alexander RW. Cholesterol depletion inhibits epidermal growth factor receptor transactivation by angiotensin II in vascular smooth muscle cells: role of cholesterol-rich microdomains and focal adhesions in angiotensin II signaling. The Journal of Biological Chemistry. 276: 48269-75. PMID 11585822 DOI: 10.1074/Jbc.M105901200  0.394
2001 Scott NA, Crocker IR, Yin Q, Sorescu D, Wilcox JN, Griendling KK. Inhibition of vascular cell growth by X-ray irradiation: Comparison with gamma radiation and mechanism of action International Journal of Radiation Oncology Biology Physics. 50: 485-493. PMID 11380238 DOI: 10.1016/S0360-3016(01)01526-7  0.328
2001 Lassègue B, Sorescu D, Szöcs K, Yin Q, Akers M, Zhang Y, Grant SL, Lambeth JD, Griendling KK. Novel gp91(phox) homologues in vascular smooth muscle cells : nox1 mediates angiotensin II-induced superoxide formation and redox-sensitive signaling pathways. Circulation Research. 88: 888-94. PMID 11348997 DOI: 10.1161/Hh0901.090299  0.51
2001 Ushio-Fukai M, Griendling KK, Becker PL, Hilenski L, Halleran S, Alexander RW. Epidermal growth factor receptor transactivation by angiotensin II requires reactive oxygen species in vascular smooth muscle cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 489-95. PMID 11304462 DOI: 10.1161/01.Atv.21.4.489  0.435
2001 Sorescu D, Somers MJ, Lassègue B, Grant S, Harrison DG, Griendling KK. Electron spin resonance characterization of the NAD(P)H oxidase in vascular smooth muscle cells. Free Radical Biology & Medicine. 30: 603-12. PMID 11295358 DOI: 10.1016/S0891-5849(00)00507-4  0.413
2001 Zafari AM, Ushio-Fukai M, Minieri CA, Akers M, Lassègue B, Griendling KK. Arachidonic acid metabolites mediate angiotensin II-induced NADH/NADPH oxidase activity and hypertrophy in vascular smooth muscle cells. Antioxidants & Redox Signaling. 1: 167-79. PMID 11228745 DOI: 10.1089/Ars.1999.1.2-167  0.415
2001 Hink U, Li H, Mollnau H, Oelze M, Matheis E, Hartmann M, Skatchkov M, Thaiss F, Stahl RA, Warnholtz A, Meinertz T, Griendling K, Harrison DG, Forstermann U, Munzel T. Mechanisms underlying endothelial dysfunction in diabetes mellitus. Circulation Research. 88: E14-22. PMID 11157681 DOI: 10.1161/01.Res.88.2.E14  0.416
2001 De Leon H, Ollerenshaw JD, Griendling KK, Wilcox JN. Adventitial Cells Do Not Contribute to Neointimal Mass After Balloon Angioplasty of the Rat Common Carotid Artery Circulation. 104: 1591-1593. DOI: 10.1161/Circ.104.14.1591  0.313
2000 Griendling KK, Sorescu D, Lassègue B, Ushio-Fukai M. Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 2175-83. PMID 11031201 DOI: 10.1161/01.Atv.20.10.2175  0.51
2000 Griendling KK, Ushio-Fukai M. Reactive oxygen species as mediators of angiotensin II signaling. Regulatory Peptides. 91: 21-7. PMID 10967199 DOI: 10.1016/S0167-0115(00)00136-1  0.421
2000 Griendling KK, Sorescu D, Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circulation Research. 86: 494-501. PMID 10720409 DOI: 10.1161/01.Res.86.5.494  0.449
2000 Grant SL, Lassègue B, Griendling KK, Ushio-Fukai M, Lyons PR, Alexander RW. Specific regulation of RGS2 messenger RNA by angiotensin II in cultured vascular smooth muscle cells. Molecular Pharmacology. 57: 460-7. PMID 10692485 DOI: 10.1124/Mol.57.3.460  0.434
2000 De Keulenaer GW, Ushio-Fukai M, Yin Q, Chung AB, Lyons PR, Ishizaka N, Rengarajan K, Taylor WR, Alexander RW, Griendling KK. Convergence of redox-sensitive and mitogen-activated protein kinase signaling pathways in tumor necrosis factor-alpha-mediated monocyte chemoattractant protein-1 induction in vascular smooth muscle cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 385-91. PMID 10669634 DOI: 10.1161/01.Atv.20.2.385  0.42
1999 Griendling KK, Harrison DG. Dual role of reactive oxygen species in vascular growth. Circulation Research. 85: 562-3. PMID 10488060 DOI: 10.1161/01.Res.85.6.562  0.402
1999 Suh YA, Arnold RS, Lassegue B, Shi J, Xu X, Sorescu D, Chung AB, Griendling KK, Lambeth JD. Cell transformation by the superoxide-generating oxidase Mox1. Nature. 401: 79-82. PMID 10485709 DOI: 10.1038/43459  0.432
1999 Ushio-Fukai M, Alexander RW, Akers M, Yin Q, Fujio Y, Walsh K, Griendling KK. Reactive oxygen species mediate the activation of Akt/protein kinase B by angiotensin II in vascular smooth muscle cells. The Journal of Biological Chemistry. 274: 22699-704. PMID 10428852 DOI: 10.1074/Jbc.274.32.22699  0.459
1999 Fukai T, Siegfried MR, Ushio-Fukai M, Griendling KK, Harrison DG. Modulation of extracellular superoxide dismutase expression by angiotensin II and hypertension. Circulation Research. 85: 23-8. PMID 10400907 DOI: 10.1161/01.Res.85.1.23  0.415
1999 Warnholtz A, Nickenig G, Schulz E, Macharzina R, Bräsen JH, Skatchkov M, Heitzer T, Stasch JP, Griendling KK, Harrison DG, Böhm M, Meinertz T, Münzel T. Increased NADH-oxidase-mediated superoxide production in the early stages of atherosclerosis: evidence for involvement of the renin-angiotensin system. Circulation. 99: 2027-33. PMID 10209008 DOI: 10.1161/01.Cir.99.15.2027  0.403
1999 Ushio-Fukai M, Alexander RW, Akers M, Lyons PR, Lassègue B, Griendling KK. Angiotensin II receptor coupling to phospholipase D is mediated by the betagamma subunits of heterotrimeric G proteins in vascular smooth muscle cells. Molecular Pharmacology. 55: 142-9. PMID 9882708 DOI: 10.1124/MOL.55.1.142  0.308
1998 Zafari AM, Ushio-Fukai M, Akers M, Yin Q, Shah A, Harrison DG, Taylor WR, Griendling KK. Role of NADH/NADPH oxidase-derived H2O2 in angiotensin II-induced vascular hypertrophy. Hypertension (Dallas, Tex. : 1979). 32: 488-95. PMID 9740615 DOI: 10.1161/01.Hyp.32.3.488  0.46
1998 Ishizaka N, Griendling KK, Lassègue B, Alexander RW. Angiotensin II type 1 receptor: relationship with caveolae and caveolin after initial agonist stimulation. Hypertension (Dallas, Tex. : 1979). 32: 459-66. PMID 9740611 DOI: 10.1161/01.Hyp.32.3.459  0.387
1998 Ushio-Fukai M, Griendling KK, Akers M, Lyons PR, Alexander RW. Temporal dispersion of activation of phospholipase C-beta1 and -gamma isoforms by angiotensin II in vascular smooth muscle cells. Role of alphaq/11, alpha12, and beta gamma G protein subunits. The Journal of Biological Chemistry. 273: 19772-7. PMID 9677408 DOI: 10.1074/Jbc.273.31.19772  0.354
1998 Griendling KK, Ushio-Fukai M. Redox control of vascular smooth muscle proliferation. The Journal of Laboratory and Clinical Medicine. 132: 9-15. PMID 9665366 DOI: 10.1016/S0022-2143(98)90019-1  0.485
1998 De Keulenaer GW, Chappell DC, Ishizaka N, Nerem RM, Alexander RW, Griendling KK. Oscillatory and steady laminar shear stress differentially affect human endothelial redox state: role of a superoxide-producing NADH oxidase. Circulation Research. 82: 1094-101. PMID 9622162 DOI: 10.1161/01.Res.82.10.1094  0.381
1998 Ushio-Fukai M, Alexander RW, Akers M, Griendling KK. p38 Mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II. Role in vascular smooth muscle cell hypertrophy. The Journal of Biological Chemistry. 273: 15022-9. PMID 9614110 DOI: 10.1074/Jbc.273.24.15022  0.483
1998 De Keulenaer GW, Alexander RW, Ushio-Fukai M, Ishizaka N, Griendling KK. Tumour necrosis factor alpha activates a p22phox-based NADH oxidase in vascular smooth muscle. The Biochemical Journal. 653-7. PMID 9445395 DOI: 10.1042/Bj3290653  0.39
1997 Ishizaka N, Alexander RW, Laursen JB, Kai H, Fukui T, Oppermann M, Lefkowitz RJ, Lyons PR, Griendling KK. G protein-coupled receptor kinase 5 in cultured vascular smooth muscle cells and rat aorta. Regulation by angiotensin II and hypertension. The Journal of Biological Chemistry. 272: 32482-8. PMID 9405459 DOI: 10.1074/Jbc.272.51.32482  0.44
1997 Ishizaka N, de León H, Laursen JB, Fukui T, Wilcox JN, De Keulenaer G, Griendling KK, Alexander RW. Angiotensin II-induced hypertension increases heme oxygenase-1 expression in rat aorta. Circulation. 96: 1923-9. PMID 9323082 DOI: 10.1161/01.Cir.96.6.1923  0.326
1997 Capers Q, Laursen JB, Fukui T, Rajagopalan S, Mori I, Lou P, Freeman BA, Berrington WR, Griendling KK, Harrison DG, Runge MS, Alexander RW, Taylor WR. Vascular thrombin receptor regulation in hypertensive rats. Circulation Research. 80: 838-44. PMID 9168786 DOI: 10.1161/01.Res.80.6.838  0.429
1997 Howard AB, Alexander RW, Nerem RM, Griendling KK, Taylor WR. Cyclic strain induces an oxidative stress in endothelial cells. The American Journal of Physiology. 272: C421-7. PMID 9124284 DOI: 10.1152/Ajpcell.1997.272.2.C421  0.358
1997 Ishizaka N, Griendling KK. Heme oxygenase-1 is regulated by angiotensin II in rat vascular smooth muscle cells. Hypertension (Dallas, Tex. : 1979). 29: 790-5. PMID 9052897 DOI: 10.1161/01.Hyp.29.3.790  0.456
1997 Griendling KK, Ushio-Fukai M, Lassègue B, Alexander RW. Angiotensin II signaling in vascular smooth muscle. New concepts. Hypertension (Dallas, Tex. : 1979). 29: 366-73. PMID 9039129 DOI: 10.1161/01.Hyp.29.1.366  0.422
1997 Fukui T, Ishizaka N, Rajagopalan S, Laursen JB, Capers Q, Taylor WR, Harrison DG, de Leon H, Wilcox JN, Griendling KK. p22phox mRNA expression and NADPH oxidase activity are increased in aortas from hypertensive rats. Circulation Research. 80: 45-51. PMID 8978321 DOI: 10.1161/01.Res.80.1.45  0.397
1996 Ushio-Fukai M, Zafari AM, Fukui T, Ishizaka N, Griendling KK. p22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells. The Journal of Biological Chemistry. 271: 23317-21. PMID 8798532 DOI: 10.1074/Jbc.271.38.23317  0.51
1996 Griendling KK, Alexander RW. Endothelial control of the cardiovascular system: recent advances. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 10: 283-92. PMID 8641561 DOI: 10.1096/Fasebj.10.2.8641561  0.433
1996 Rajagopalan S, Kurz S, Münzel T, Tarpey M, Freeman BA, Griendling KK, Harrison DG. Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone. The Journal of Clinical Investigation. 97: 1916-23. PMID 8621776 DOI: 10.1172/Jci118623  0.43
1995 Fukui T, Lassègue B, Kai H, Alexander RW, Griendling KK. Cytochrome b-558 alpha-subunit cloning and expression in rat aortic smooth muscle cells. Biochimica Et Biophysica Acta. 1231: 215-9. PMID 7578211 DOI: 10.1016/0005-2728(95)00098-4  0.345
1994 Griendling KK, Minieri CA, Ollerenshaw JD, Alexander RW. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circulation Research. 74: 1141-8. PMID 8187280 DOI: 10.1161/01.Res.74.6.1141  0.467
1994 Rao GN, Lassègue B, Alexander RW, Griendling KK. Angiotensin II stimulates phosphorylation of high-molecular-mass cytosolic phospholipase A2 in vascular smooth-muscle cells. The Biochemical Journal. 197-201. PMID 8166641 DOI: 10.1042/Bj2990197  0.447
1994 Kai H, Griendling KK, Lassègue B, Ollerenshaw JD, Runge MS, Alexander RW. Agonist-induced phosphorylation of the vascular type 1 angiotensin II receptor. Hypertension (Dallas, Tex. : 1979). 24: 523-7. PMID 8088922 DOI: 10.1161/01.Hyp.24.4.523  0.371
1993 Lassègue B, Alexander RW, Clark M, Akers M, Griendling KK. Phosphatidylcholine is a major source of phosphatidic acid and diacylglycerol in angiotensin II-stimulated vascular smooth-muscle cells. The Biochemical Journal. 509-17. PMID 8503884 DOI: 10.1042/Bj2920509  0.431
1993 Rao GN, Lasségue B, Griendling KK, Alexander RW, Berk BC. Hydrogen peroxide-induced c-fos expression is mediated by arachidonic acid release: role of protein kinase C. Nucleic Acids Research. 21: 1259-63. PMID 8464709 DOI: 10.1093/Nar/21.5.1259  0.327
1993 Griendling KK, Lassègue B, Wayne Alexander R. The Vascular Angiotensin (AT1) Receptor Thrombosis and Haemostasis. 70: 188-192. DOI: 10.1055/S-0038-1646187  0.341
1991 Murphy TJ, Alexander RW, Griendling KK, Runge MS, Bernstein KE. Isolation of a cDNA encoding the vascular type-1 angiotensin II receptor Nature. 351: 233-236. PMID 2041570 DOI: 10.1038/351233A0  0.345
1991 Berk BC, Taubman MB, Griendling KK, Cragoe EJ, Fenton JW, Brock TA. Thrombin-stimulated events in cultured vascular smooth-muscle cells. The Biochemical Journal. 274: 799-805. PMID 2012607 DOI: 10.1042/Bj2740799  0.371
1991 Lassègue B, Alexander RW, Clark M, Griendling KK. Angiotensin II-induced phosphatidylcholine hydrolysis in cultured vascular smooth-muscle cells. Regulation and localization. The Biochemical Journal. 19-25. PMID 1903932 DOI: 10.1042/Bj2760019  0.418
1990 Griendling KK, Berk BC, Socorro L, Tsuda T, Delafontaine P, Alexander RW. Secondary signalling mechanisms in angiotensin II-stimulated vascular smooth muscle cells. Clinical and Experimental Pharmacology & Physiology. 15: 105-12. PMID 3078271 DOI: 10.1111/J.1440-1681.1988.Tb01051.X  0.33
1990 Socorro L, Alexander RW, Griendling KK. Cholera toxin modulation of angiotensin II-stimulated inositol phosphate production in cultured vascular smooth muscle cells. The Biochemical Journal. 265: 799-807. PMID 2154969 DOI: 10.1042/Bj2650799  0.409
1990 Barnett JV, Shamah SM, Lassegue B, Griendling KK, Galper JB. Muscarinic cholinergic stimulation of inositol phosphate production in cultured embryonic chick atrial cells. Evidence for a role of two guanine-nucleotide-binding proteins. The Biochemical Journal. 271: 437-42. PMID 2122887 DOI: 10.1042/Bj2710437  0.321
1989 Griendling KK, Tsuda T, Berk BC, Alexander RW. Angiotensin II stimulation of vascular smooth muscle cells. Secondary signalling mechanisms. American Journal of Hypertension. 2: 659-65. PMID 2673302 DOI: 10.1093/ajh/2.8.659  0.318
1987 Griendling KK, Berk BC, Ganz P, Gimbrone MA, Alexander RW. Angiotensin II stimulation of vascular smooth muscle phosphoinositide metabolism. State of the art lecture. Hypertension (Dallas, Tex. : 1979). 9: III181-5. PMID 3036701 DOI: 10.1161/01.Hyp.9.6_Pt_2.Iii181  0.329
1987 Berk BC, Nabel EG, Griendling KK, Smith TW, Alexander RW. Vasoconstrictor-mediated ionic events associated with sustained contractile responses in cultured vascular smooth muscle cells Journal of Molecular and Cellular Cardiology. 19: S5. DOI: 10.1016/S0022-2828(87)80640-5  0.395
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