| Year |
Citation |
Score |
| 2023 |
Schuermans A, Vlasschaert C, Nauffal V, Cho SMJ, Uddin MM, Nakao T, Niroula A, Klarqvist MDR, Weeks LD, Lin AE, Saadatagah S, Lannery K, Wong M, Hornsby W, Lubitz SA, ... ... Ebert BL, et al. Clonal haematopoiesis of indeterminate potential predicts incident cardiac arrhythmias. European Heart Journal. PMID 37952204 DOI: 10.1093/eurheartj/ehad670 |
0.643 |
|
| 2023 |
Ahmad MH, Hegde M, Wong WJ, M Hosseini M, Garrett LJ, Carrascoso A, Issac N, Ebert BL, Silva JC, Pihan G, Zhu LJ, Wolfe S, Agarwal A, Liu PP, Castilla LH. Runx1-R188Q germline mutation induces inflammation and predisposition to hematologic malignancies in mice. Blood Advances. PMID 37756546 DOI: 10.1182/bloodadvances.2023010398 |
0.305 |
|
| 2023 |
Yu Z, Filder TP, Ruan Y, Vlasschaert C, Nakao T, Uddin MM, Mack T, Niroula A, Heimlich JB, Zekavat SM, Gibson CJ, Griffin GK, Wang Y, Peloso GM, Heard-Costa N, ... ... Ebert BL, et al. Genetic modification of inflammation and clonal hematopoiesis-associated cardiovascular risk. The Journal of Clinical Investigation. PMID 37498674 DOI: 10.1172/JCI168597 |
0.654 |
|
| 2023 |
Weeks LD, Niroula A, Neuberg D, Wong W, Lindsley RC, Luskin M, Berliner N, Stone RM, DeAngelo DJ, Soiffer R, Uddin MM, Griffin G, Vlasschaert C, Gibson CJ, Jaiswal S, ... ... Ebert BL, et al. Prediction of risk for myeloid malignancy in clonal hematopoiesis. Nejm Evidence. 2. PMID 37483562 DOI: 10.1056/evidoa2200310 |
0.657 |
|
| 2023 |
Wong WJ, Emdin C, Bick AG, Zekavat SM, Niroula A, Pirruccello JP, Dichtel L, Griffin G, Uddin MM, Gibson CJ, Kovalcik V, Lin AE, McConkey ME, Vromman A, Sellar RS, ... ... Ebert BL, et al. Author Correction: Clonal haematopoiesis and risk of chronic liver disease. Nature. PMID 37400552 DOI: 10.1038/s41586-023-06375-z |
0.593 |
|
| 2023 |
Marion W, Koppe T, Chen CC, Wang D, Frenis K, Fierstein S, Sensharma P, Aumais O, Peters M, Ruiz-Torres S, Chihanga T, Boettcher S, Shimamura A, Bauer DE, Schlaeger T, ... ... Ebert BL, et al. RUNX1 mutations mitigate quiescence to promote transformation of hematopoietic progenitors in Fanconi anemia. Leukemia. PMID 37391485 DOI: 10.1038/s41375-023-01945-6 |
0.308 |
|
| 2023 |
Schuermans A, Nakao T, Ruan Y, Koyama S, Yu Z, Uddin MM, Haidermota S, Hornsby W, Lewandowski AJ, Bick AG, Niroula A, Jaiswal S, Ebert BL, Natarajan P, Honigberg MC. Birth Weight Is Associated With Clonal Hematopoiesis of Indeterminate Potential and Cardiovascular Outcomes in Adulthood. Journal of the American Heart Association. e030220. PMID 37345823 DOI: 10.1161/JAHA.123.030220 |
0.624 |
|
| 2023 |
Gumuser ED, Schuermans A, Cho SMJ, Sporn ZA, Uddin MM, Paruchuri K, Nakao T, Yu Z, Haidermota S, Hornsby W, Weeks LD, Niroula A, Jaiswal S, Libby P, Ebert BL, et al. Clonal Hematopoiesis of Indeterminate Potential Predicts Adverse Outcomes in Patients With Atherosclerotic Cardiovascular Disease. Journal of the American College of Cardiology. 81: 1996-2009. PMID 37197843 DOI: 10.1016/j.jacc.2023.03.401 |
0.67 |
|
| 2023 |
Wong WJ, Emdin C, Bick AG, Zekavat SM, Niroula A, Pirruccello JP, Dichtel L, Griffin G, Uddin MM, Gibson CJ, Kovalcik V, Lin AE, McConkey ME, Vromman A, Sellar RS, ... ... Ebert BL, et al. Clonal haematopoiesis and risk of chronic liver disease. Nature. PMID 37046084 DOI: 10.1038/s41586-023-05857-4 |
0.604 |
|
| 2023 |
Vlasschaert C, Mack T, Heimlich JB, Niroula A, Uddin MM, Weinstock JS, Sharber B, Silver AJ, Xu Y, Savona MR, Gibson CJ, Lanktree MB, Rauh MJ, Ebert BL, Natarajan P, et al. A practical approach to curate clonal hematopoiesis of indeterminate potential in human genetic datasets. Blood. PMID 36652671 DOI: 10.1182/blood.2022018825 |
0.645 |
|
| 2022 |
Duncavage EJ, Bagg A, Hasserjian RP, DiNardo CD, Godley LA, Iacobucci I, Jaiswal S, Malcovati L, Vannucchi AM, Patel KP, Arber DA, Arcila ME, Bejar R, Berliner N, Borowitz MJ, ... ... Ebert BL, et al. Genomic Profiling for Clinical Decision Making in Myeloid Neoplasms and Acute Leukemia. Blood. PMID 36130297 DOI: 10.1182/blood.2022015853 |
0.637 |
|
| 2022 |
Uddin MDM, Nguyen NQH, Yu B, Brody JA, Pampana A, Nakao T, Fornage M, Bressler J, Sotoodehnia N, Weinstock JS, Honigberg MC, Nachun D, Bhattacharya R, Griffin GK, Chander V, ... ... Ebert BL, et al. Clonal hematopoiesis of indeterminate potential, DNA methylation, and risk for coronary artery disease. Nature Communications. 13: 5350. PMID 36097025 DOI: 10.1038/s41467-022-33093-3 |
0.669 |
|
| 2022 |
Miller PG, Sathappa M, Moroco JA, Jiang W, Qian Y, Iqbal S, Guo Q, Giacomelli AO, Shaw S, Vernier C, Bajrami B, Yang X, Raffier C, Sperling AS, Gibson CJ, ... ... Ebert BL, et al. Allosteric inhibition of PPM1D serine/threonine phosphatase via an altered conformational state. Nature Communications. 13: 3778. PMID 35773251 DOI: 10.1038/s41467-022-30463-9 |
0.704 |
|
| 2022 |
Agrawal M, Niroula A, Cunin P, McConkey M, Kovalcik V, Kim PG, Wong WJ, Weeks LD, Lin AE, Miller PG, Gibson CJ, Sekar A, Schaefer IM, Neuberg D, Stone RM, ... ... Ebert BL, et al. TET2-mutant clonal hematopoiesis and risk of gout. Blood. PMID 35714308 DOI: 10.1182/blood.2022015384 |
0.62 |
|
| 2022 |
Nakao T, Bick AG, Taub MA, Zekavat SM, Uddin MM, Niroula A, Carty CL, Lane J, Honigberg MC, Weinstock JS, Pampana A, Gibson CJ, Griffin GK, Clarke SL, Bhattacharya R, ... ... Ebert BL, et al. Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential. Science Advances. 8: eabl6579. PMID 35385311 DOI: 10.1126/sciadv.abl6579 |
0.64 |
|
| 2021 |
Miller P, Qiao D, Rojas-Quintero J, Honigberg MC, Sperling AS, Gibson CJ, Bick AG, Niroula A, McConkey ME, Sandoval B, Miller B, Shi W, Viswanathan K, Leventhal MJ, Werner L, ... ... Ebert BL, et al. Association of Clonal Hematopoiesis with Chronic Obstructive Pulmonary Disease. Blood. PMID 34855941 DOI: 10.1182/blood.2021013531 |
0.639 |
|
| 2021 |
Bhattacharya R, Zekavat SM, Haessler J, Fornage M, Raffield L, Uddin MM, Bick AG, Niroula A, Yu B, Gibson C, Griffin G, Morrison AC, Psaty BM, Longstreth WT, Bis JC, ... ... Ebert BL, et al. Clonal Hematopoiesis Is Associated With Higher Risk of Stroke. Stroke. STROKEAHA121037388. PMID 34743536 DOI: 10.1161/STROKEAHA.121.037388 |
0.589 |
|
| 2021 |
Kim PG, Niroula A, Shkolnik V, McConkey M, Lin AE, Słabicki M, Kemp JP, Bick A, Gibson CJ, Griffin G, Sekar A, Brooks DJ, Wong WJ, Cohen DN, Uddin MM, ... ... Ebert BL, et al. Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis. The Journal of Experimental Medicine. 218. PMID 34698806 DOI: 10.1084/jem.20211872 |
0.645 |
|
| 2021 |
Niroula A, Sekar A, Murakami MA, Trinder M, Agrawal M, Wong WJ, Bick AG, Uddin MM, Gibson CJ, Griffin GK, Honigberg MC, Zekavat SM, Paruchuri K, Natarajan P, Ebert BL. Distinction of lymphoid and myeloid clonal hematopoiesis. Nature Medicine. PMID 34663986 DOI: 10.1038/s41591-021-01521-4 |
0.312 |
|
| 2021 |
Beauchamp EM, Leventhal M, Bernard E, Hoppe ER, Todisco G, Creignou M, Gallì A, Castellano CA, McConkey M, Tarun A, Wong W, Schenone M, Stanclift C, Tanenbaum B, Malolepsza E, ... ... Ebert BL, et al. is mutated in clonal hematopoiesis and myelodysplastic syndromes and impacts RNA splicing. Blood Cancer Discovery. 2: 500-517. PMID 34568833 DOI: 10.1158/2643-3230.BCD-20-0224 |
0.666 |
|
| 2021 |
Huang YH, Chen CW, Sundaramurthy V, Slabicki M, Hao D, Watson CJ, Tovy A, Reyes JM, Dakhova O, Crovetti BR, Galonska C, Lee M, Brunetti L, Zhou Y, Tatton-Brown K, ... ... Ebert BL, et al. Systematic profiling of DNMT3A variants reveals protein instability mediated by the DCAF8 E3 ubiquitin ligase adaptor. Cancer Discovery. PMID 34429321 DOI: 10.1158/2159-8290.CD-21-0560 |
0.306 |
|
| 2021 |
Bick AG, Weinstock JS, Nandakumar SK, Fulco CP, Bao EL, Zekavat SM, Szeto MD, Liao X, Leventhal MJ, Nasser J, Chang K, Laurie C, Burugula BB, Gibson CJ, Niroula A, ... ... Ebert BL, et al. Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes. Nature. PMID 33707633 DOI: 10.1038/s41586-021-03280-1 |
0.579 |
|
| 2021 |
Iacobucci I, Qu C, Varotto E, Janke LJ, Yang X, Seth A, Shelat A, Friske J, Fukano R, Yu J, Freeman BB, Kennedy JA, Sperling AS, Zheng R, Wang Y, ... ... Ebert BL, et al. Modeling and targeting of erythroleukemia by hematopoietic genome editing. Blood. PMID 33512458 DOI: 10.1182/blood.2020009103 |
0.313 |
|
| 2020 |
Bick AG, Weinstock JS, Nandakumar SK, Fulco CP, Bao EL, Zekavat SM, Szeto MD, Liao X, Leventhal MJ, Nasser J, Chang K, Laurie C, Burugula BB, Gibson CJ, Lin AE, ... ... Ebert BL, et al. Inherited causes of clonal haematopoiesis in 97,691 whole genomes. Nature. PMID 33057201 DOI: 10.1038/s41586-020-2819-2 |
0.687 |
|
| 2020 |
Sidlow R, Lin AE, Gupta D, Bolton KL, Steensma DP, Levine RL, Ebert BL, Libby P. The Clinical Challenge of Clonal Hematopoiesis, a Newly Recognized Cardiovascular Risk Factor. Jama Cardiology. PMID 32459358 DOI: 10.1001/jamacardio.2020.1271 |
0.31 |
|
| 2019 |
Steensma DP, Ebert BL. Clonal hematopoiesis as a model for premalignant changes during aging. Experimental Hematology. PMID 31838005 DOI: 10.1016/j.exphem.2019.12.001 |
0.327 |
|
| 2019 |
Jaiswal S, Ebert BL. Clonal hematopoiesis in human aging and disease. Science (New York, N.Y.). 366. PMID 31672865 DOI: 10.1126/Science.Aan4673 |
0.665 |
|
| 2019 |
Libby P, Sidlow R, Lin AE, Gupta D, Jones LW, Moslehi J, Zeiher A, Jaiswal S, Schulz C, Blankstein R, Bolton KL, Steensma D, Levine RL, Ebert BL. Clonal Hematopoiesis: Crossroads of Aging, Cardiovascular Disease, and Cancer: JACC Review Topic of the Week. Journal of the American College of Cardiology. 74: 567-577. PMID 31345432 DOI: 10.1016/J.Jacc.2019.06.007 |
0.648 |
|
| 2019 |
Iacobucci I, Wen J, Meggendorfer M, Choi JK, Shi L, Pounds SB, Carmichael CL, Masih KE, Morris SM, Lindsley RC, Janke LJ, Alexander TB, Song G, Qu C, Li Y, ... ... Ebert BL, et al. Genomic subtyping and therapeutic targeting of acute erythroleukemia. Nature Genetics. 51: 694-704. PMID 30926971 DOI: 10.1038/S41588-019-0375-1 |
0.306 |
|
| 2019 |
De Matos Simoes R, Shirasaki R, Downey-Kopyscinski SL, Matthews G, Yiguo H, Sheffer M, Dhimolea E, Dashevsky O, Gandolfi S, Dempster J, Meyers RM, Bryan J, McFarland JM, Brueggenthies J, Tang H, ... ... Ebert B, et al. Systematic Characterization of Genes Representing Preferential Molecular Vulnerabilities for Myeloma Cells Compared to Other Neoplasias - Implications for the Biology and Therapeutic Targeting of Myeloma Blood. 134: 4407-4407. DOI: 10.1182/Blood-2019-130901 |
0.347 |
|
| 2019 |
Vallurupalli M, Gorelov R, Garcia JS, Morgan EA, Ebert B, Tothova Z. Talazoparib Treatment Preferentially Depletes Cohesin-Mutant Clones in New In Vivo Models of Cohesin-Mutant Myeloid Diseases Blood. 134: 560-560. DOI: 10.1182/Blood-2019-130308 |
0.387 |
|
| 2019 |
Goll JB, Lindsley RC, Hooper WF, Bejar R, Walker J, Fulton R, Abel GA, Al Baghdadi T, Deeg HJ, DeZern AE, Ebert B, Epling-Burnette P, Foran JM, Gorak EJ, Gore SD, et al. Clonal Cytopenias of Undetermined Significance Are Common in Cytopenic Adults Evaluated for MDS in the National MDS Study Blood. 134: 4271-4271. DOI: 10.1182/Blood-2019-126978 |
0.368 |
|
| 2018 |
Libby P, Jaiswal S, Lin AE, Ebert BL. CHIPping Away at the Pathogenesis of Heart Failure. Jama Cardiology. PMID 30566187 DOI: 10.1001/Jamacardio.2018.4039 |
0.561 |
|
| 2018 |
Sellar RS, Jaiswal S, Ebert BL. Predicting progression to AML. Nature Medicine. 24: 904-906. PMID 29988142 DOI: 10.1038/S41591-018-0114-7 |
0.651 |
|
| 2018 |
Kahn JD, Miller PG, Silver AJ, Sellar RS, Bhatt S, Gibson C, McConkey M, Adams D, Mar B, Mertins P, Fereshetian S, Krug K, Zhu H, Letai A, Carr SA, ... ... Ebert BL, et al. PPM1D truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells. Blood. PMID 29954749 DOI: 10.1182/Blood-2018-05-850339 |
0.663 |
|
| 2018 |
Iacobucci I, Varotto E, Qu C, Janke L, Seth A, Shelat A, Freeman B, Kennedy J, Sperling AS, Lindsley RC, Dickerson K, Payne-Turner D, Morris SM, Ghosn N, Ebert BL, et al. Multiplex CRISPR/Cas9-Based Genome Editing of Mouse Hematopoietic Stem Cells Recapitulates Acute Erythroid Leukemia and Identifies Therapeutic Targets Blood. 132: 5-5. DOI: 10.1182/Blood-2018-99-118817 |
0.331 |
|
| 2018 |
Rauch PJ, Silver AJ, Gopakumar J, McConkey M, Sinha E, Fefer M, Shvartz E, Sukhova G, Libby P, Ebert BL, Jaiswal S. Loss-of-Function Mutations in Dnmt3a and Tet2 Lead to Accelerated Atherosclerosis and Convergent Macrophage Phenotypes in Mice Blood. 132: 745-745. DOI: 10.1182/Blood-2018-99-118288 |
0.666 |
|
| 2018 |
Wang L, Yin S, Martinez Az, Regis FF, Brooks A, Herman SEM, Ten Hacken E, Obeng E, Campagna D, Fleming MD, Ebert BL, Wiestner A, Leshchiner I, Getz G, Carrasco RD, et al. Integrated Genomic and Proteomic Analysis of Murine CLL-like Cells Reveals SF3B1 Mutation to Impact DNA Damage Response and BCR Signaling Blood. 132: 947-947. DOI: 10.1182/Blood-2018-99-117691 |
0.332 |
|
| 2018 |
Renella R, Gagne K, Beauchamp E, Schlaeger T, Hofmann I, Shimamura A, Fogel J, Agarwal S, Ebert BL, Markianos K, Springer TA, Fleming MD, Williams DA. Congenital X-Linked Myelodysplasia with Tetraploidy Is Associated with De Novo Germline C-Terminal Mutation of SEPT6, a Septin Filament Protein Blood. 132: 644-644. DOI: 10.1182/Blood-2018-99-114682 |
0.332 |
|
| 2017 |
Jaiswal S, Natarajan P, Ebert BL. Clonal Hematopoiesis and Atherosclerosis. The New England Journal of Medicine. 377: 1401-1402. PMID 28976867 DOI: 10.1056/Nejmc1710381 |
0.596 |
|
| 2017 |
Jaiswal S, Natarajan P, Silver AJ, Gibson CJ, Bick AG, Shvartz E, McConkey M, Gupta N, Gabriel S, Ardissino D, Baber U, Mehran R, Fuster V, Danesh J, Frossard P, ... ... Ebert BL, et al. Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease. The New England Journal of Medicine. PMID 28636844 DOI: 10.1056/Nejmoa1701719 |
0.655 |
|
| 2017 |
Jan M, Ebert BL, Jaiswal S. Clonal hematopoiesis. Seminars in Hematology. 54: 43-50. PMID 28088988 DOI: 10.1053/j.seminhematol.2016.10.002 |
0.678 |
|
| 2017 |
Gibson CJ, Lindsley RC, Tchekmedyian V, Mar BG, Shi J, Jaiswal S, Bosworth A, Francisco L, He J, Bansal A, Morgan EA, Lacasce AS, Freedman AS, Fisher DC, Jacobsen E, ... ... Ebert BL, et al. Clonal Hematopoiesis Associated With Adverse Outcomes After Autologous Stem-Cell Transplantation for Lymphoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2016716712. PMID 28068180 DOI: 10.1200/Jco.2016.71.6712 |
0.655 |
|
| 2016 |
Li H, Mar BG, Zhang H, Puram RV, Vazquez F, Weir BA, Hahn WC, Ebert B, Pellman D. The EMT regulator ZEB2 is a novel dependency of human and murine acute myeloid leukemia. Blood. PMID 27756750 DOI: 10.1182/Blood-2016-05-714493 |
0.357 |
|
| 2016 |
Gibson CJ, Lindsley RC, Tchekmedyian V, Shi J, Mar BG, Jaiswal S, Bosworth A, Francisco LF, He J, Morgan EA, LaCasce AS, Koreth J, Ho VT, Ritz J, Nikiforow S, ... ... Ebert BL, et al. Clonal Hematopoiesis Associated with Adverse Outcomes Following Autologous Stem Cell Transplantation for Non-Hodgkin Lymphoma Blood. 128: 986-986. DOI: 10.1182/Blood.V128.22.986.986 |
0.664 |
|
| 2016 |
Wang L, Gambe R, Sun J, Shukla S, Kim J, Brooks AN, Neuberg DS, Fleming MD, Ebert BL, Carrasco RD, Wu CJ. Genome-Wide Analysis of a Novel Murine Model of Chronic Lymphocytic Leukemia Blood. 128: 967-967. DOI: 10.1182/Blood.V128.22.967.967 |
0.313 |
|
| 2016 |
Tothova Z, Krill-Burger JM, Popova KD, Sievers Q, Yudovich D, Belizaire R, Aster JC, Morgan EA, Tsherniak A, Ebert BL. Generation of Models of Human Hematologic Malignancies Using CRISPR Genome Engineering Blood. 128: 741-741. DOI: 10.1182/Blood.V128.22.741.741 |
0.319 |
|
| 2016 |
Kahn J, Silver AJ, Mertins P, Carr S, Jaiswal S, Ebert BL. PPM1D Truncating Mutations Confer Chemotherapy Resistance in Hematopoietic Stem Cells, Which Is Reversible By PPM1D Inhibition Blood. 128: 740-740. DOI: 10.1182/Blood.V128.22.740.740 |
0.649 |
|
| 2016 |
Vu LP, Prieto C, Amin E, Minuesa G, Chhangawala S, Vidal MJ, Krivtsov AV, Chou T, Barlowe T, Taggart J, Tivnan P, Deering RP, Gonen M, Figueroa ME, Paietta E, ... ... Ebert B, et al. RNA Binding Protein Syncrip Regulates the Leukemia Stem Cell Program Blood. 128: 739-739. DOI: 10.1182/Blood.V128.22.739.739 |
0.353 |
|
| 2016 |
McGraw K, Cheng C, Chen A, Genovese G, Cluzeau T, Lin H, Przychodzen B, Mallo M, Arenillas L, Mohamedali A, Ades L, Basiorka A, Irvine B, Sallman D, Padron E, ... ... Ebert B, et al. Abstract 2570: Identification of genetic polymorphisms associated with myelodysplastic syndromes by genome-wide association study Cancer Research. 76: 2570-2570. DOI: 10.1158/1538-7445.Am2016-2570 |
0.324 |
|
| 2016 |
Wang L, Brooks A, Gambe R, Fan J, Sun J, Hergert S, Wan Y, Neuberg D, Kharchenko P, Meyerson M, Fleming M, Ebert B, Wu C. From Human Genetic to Mouse Model: SF3B1 Mutation and its Impact on Chronic Lymphocytic Leukemia Clinical Lymphoma Myeloma and Leukemia. 16: S52. DOI: 10.1016/J.Clml.2016.07.076 |
0.338 |
|
| 2015 |
Steensma DP, Bejar R, Jaiswal S, Lindsley RC, Sekeres MA, Hasserjian RP, Ebert BL. Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes. Blood. 126: 9-16. PMID 25931582 DOI: 10.1182/Blood-2015-03-631747 |
0.68 |
|
| 2015 |
Genovese G, Jaiswal S, Ebert BL, McCarroll SA. Clonal hematopoiesis and blood-cancer risk. The New England Journal of Medicine. 372: 1071-2. PMID 25760361 DOI: 10.1056/NEJMc1500684 |
0.605 |
|
| 2015 |
Yoda A, Adelmant G, Tamburini J, Chapuy B, Shindoh N, Yoda Y, Weigert O, Kopp N, Wu SC, Kim SS, Liu H, Tivey T, Christie AL, Elpek KG, Card J, ... ... Ebert BL, et al. Mutations in G protein β subunits promote transformation and kinase inhibitor resistance. Nature Medicine. 21: 71-5. PMID 25485910 DOI: 10.1038/Nm.3751 |
0.638 |
|
| 2015 |
Ebert BL. Clonal Diversity and Mutated Genes in Myelodysplastic Syndromes Blood. 126: SCI-3-SCI-3. DOI: 10.1182/blood.v126.23.sci-3.sci-3 |
0.316 |
|
| 2015 |
Sigmans J, Noort W, Lindsley C, Pan L, Aalders L, Bariteau M, Ebert B, Aster J, Steidl U, Schuringa J, Yuan H, Bruijn Jd, Raymakers R, Lokhorst H, Mutis T, et al. Abstract PR12: Biological insights into tumor-bone marrow microenvironment interactions derived from a humanized murine model Cancer Research. 75. DOI: 10.1158/1538-7445.Chtme14-Pr12 |
0.316 |
|
| 2015 |
Ebert B. Abstract SY13-03: Novel targeted therapies in myelodysplastic syndrome Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Sy13-03 |
0.307 |
|
| 2015 |
Buonamici S, Perino S, Lim K, Darman R, Feala J, Peng S, Bhavsar E, Corson L, Keaney G, Mizui Y, Obeng E, Park E, Wang J, Warmuth M, Yu L, ... ... Ebert B, et al. 21 SF3B1 MUTATIONS INDUCE ABERRANT SPLICING LEADING TO A BLOCK IN ERYTHROID DIFFERENTIATION AND COMPETITIVE ADVANTAGE Leukemia Research. 39: S9. DOI: 10.1016/S0145-2126(15)30022-9 |
0.304 |
|
| 2014 |
Jaiswal S, Fontanillas P, Flannick J, Manning A, Grauman PV, Mar BG, Lindsley RC, Mermel CH, Burtt N, Chavez A, Higgins JM, Moltchanov V, Kuo FC, Kluk MJ, Henderson B, ... ... Ebert BL, et al. Age-related clonal hematopoiesis associated with adverse outcomes. The New England Journal of Medicine. 371: 2488-98. PMID 25426837 DOI: 10.1056/Nejmoa1408617 |
0.651 |
|
| 2014 |
Jaiswal S, Ebert BL. MDS is a stem cell disorder after all Cancer Cell. 25: 713-714. PMID 24937455 DOI: 10.1016/J.Ccr.2014.06.001 |
0.628 |
|
| 2014 |
Lindsley RC, Mar BG, Mazzola E, Grauman P, Shareef S, DeAngelo DJ, Neuberg DS, Stone RM, Ebert BL. Ontogeny-Specific Patterns of Genetic Alterations in Acute Myeloid Leukemia Blood. 124: 18-18. DOI: 10.1182/blood.v124.21.18.18 |
0.301 |
|
| 2012 |
Bejar R, Stevenson KE, Stojanov P, Zaneveld JE, Bar-Natan M, Caughey B, Wang H, Garcia-Manero G, Kantarjian HM, Cutler C, Ritz J, Cibulskis K, Getz G, Steensma DP, Stone RM, ... ... Ebert BL, et al. Detection of Recurrent Mutations by Pooled Targeted Next-Generation Sequencing in MDS Patients Prior to Treatment with Hypomethylating Agents or Stem Cell Transplantation Blood. 120: 311-311. DOI: 10.1182/Blood.V120.21.311.311 |
0.327 |
|
| 2011 |
Ebert B, Bernard OA. Mutations in RNA splicing machinery in human cancers. The New England Journal of Medicine. 365: 2534-5. PMID 22150007 DOI: 10.1056/Nejme1111584 |
0.331 |
|
| 2011 |
Bejar R, Stevenson K, Caughey B, Abdel-Wahab O, Galili N, Garcia-Manero G, Kantarjian HM, Raza A, Steensma DP, Levine RL, Neuberg D, Ebert BL. Validation of a Prognostic Model and the Impact of SF3B1, DNMT3A, and Other Mutations in 289 Genetically Characterized Lower Risk MDS Patient Samples Blood. 118: 969-969. DOI: 10.1182/Blood.V118.21.969.969 |
0.3 |
|
| 2011 |
Ashton JM, Balys M, Neering S, Cowley G, Root DE, Miller PG, Ebert B, McMurray H, Hassane DC, Land H, Jordan CT. Oncogene Cooperativity Analysis Reveals a Novel Set of Genes That Regulate the In Vivo Growth and Survival of Leukemia Stem Cells Blood. 118: 553-553. DOI: 10.1182/Blood.V118.21.553.553 |
0.368 |
|
| 2011 |
Bejar R, Stevenson K, Abdel-Wahab O, Galili N, Nilsson B, Garcia-Manero G, Kantarjian H, Raza A, Levine R, Neuberg D, Ebert B. 288 Point mutations in myelodysplastic syndromes: Associations with clinical features and independent predictors of overall survival Leukemia Research. 35: S113. DOI: 10.1016/S0145-2126(11)70290-9 |
0.323 |
|
| 2010 |
Bejar R, Stevenson K, Abdel-Wahab O, Marie M, Lin K, McAuley JR, Cheung K, Galili N, Garcia-Manero G, Kantarjian H, Raza A, Levine R, Neuberg D, Ebert BL. Point Mutations In Myelodysplastic Syndromes Are Associated with Clinical Features and Are Independent Predictors of Overall Survival Blood. 116: 300-300. DOI: 10.1182/Blood.V116.21.300.300 |
0.305 |
|
| 1997 |
Ratcliffe PJ, Ebert BL, Firth JD, Gleadle JM, Maxwell PH, Nagao M, O'Rourke JF, Pugh CW, Wood SM. Oxygen regulated gene expression: erythropoietin as a model system. Kidney International. 51: 514-26. PMID 9027732 DOI: 10.1038/Ki.1997.72 |
0.398 |
|
| 1996 |
Nagao M, Ebert BL, Ratcliffe PJ, Pugh CW. Drosophila melanogaster SL2 cells contain a hypoxically inducible DNA binding complex which recognises mammalian HIF-binding sites. Febs Letters. 387: 161-6. PMID 8674541 DOI: 10.1016/0014-5793(96)00484-X |
0.418 |
|
| 1996 |
Ebert BL, Gleadle JM, O'Rourke JF, Bartlett SM, Poulton J, Ratcliffe PJ. Isoenzyme-specific regulation of genes involved in energy metabolism by hypoxia: similarities with the regulation of erythropoietin. The Biochemical Journal. 809-14. PMID 8611159 DOI: 10.1042/Bj3130809 |
0.414 |
|
| 1996 |
Gleadle JM, Ebert BL, Ratcliffe PJ. Diphenylene iodonium inhibits the induction of erythropoietin and other mammalian genes by hypoxia. Implications for the mechanism of oxygen sensing. European Journal of Biochemistry. 234: 92-9. PMID 8529674 DOI: 10.1111/J.1432-1033.1995.092_C.X |
0.472 |
|
| 1996 |
Ebert BL, Firth JD, Ratcliffe PJ. Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences. The Journal of Biological Chemistry. 270: 29083-9. PMID 7493931 DOI: 10.1074/Jbc.270.49.29083 |
0.413 |
|
| 1995 |
Firth JD, Ebert BL, Ratcliffe PJ. Hypoxic regulation of lactate dehydrogenase A. Interaction between hypoxia-inducible factor 1 and cAMP response elements. The Journal of Biological Chemistry. 270: 21021-7. PMID 7673128 DOI: 10.1074/Jbc.270.36.21021 |
0.443 |
|
| 1995 |
Ratcliffe PJ, Ebert BL, Ferguson DJ, Firth JD, Gleadle JM, Maxwell PH, Pugh CW. Regulation of the erythropoietin gene. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 18-27. PMID 7644101 DOI: 10.1093/Ndt/10.Supp2.18 |
0.398 |
|
| 1995 |
Gleadle JM, Ebert BL, Firth JD, Ratcliffe PJ. Regulation of angiogenic growth factor expression by hypoxia, transition metals, and chelating agents. The American Journal of Physiology. 268: C1362-8. PMID 7541940 DOI: 10.1152/Ajpcell.1995.268.6.C1362 |
0.419 |
|
| 1995 |
Gleadle J, Ebert B, Firth J, Ratcliffe P. Oxygen Sensing and Vascular Growth Factor Gene Expression: Comparison with Erythropoietin Regulation Clinical Science. 88. DOI: 10.1042/Cs088002Pa |
0.461 |
|
| 1994 |
Pugh CW, Ebert BL, Ebrahim O, Maxwell PH, Ratcliffe PJ, Caro J, Acker H, Goldwasser E. Analysis of cis-acting sequences required for operation of the erythropoietin 3' enhancer in different cell lines Annals of the New York Academy of Sciences. 718: 31-40. PMID 8185238 DOI: 10.1111/J.1749-6632.1994.Tb55701.X |
0.406 |
|
| 1994 |
Pugh CW, Ebert BL, Ebrahim O, Ratcliffe PJ. Characterisation of functional domains within the mouse erythropoietin 3' enhancer conveying oxygen-regulated responses in different cell lines. Biochimica Et Biophysica Acta. 1217: 297-306. PMID 8148375 DOI: 10.1016/0167-4781(94)90289-5 |
0.431 |
|
| 1994 |
Firth JD, Ebert BL, Pugh CW, Ratcliffe PJ. Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer. Proceedings of the National Academy of Sciences of the United States of America. 91: 6496-500. PMID 8022811 DOI: 10.1073/Pnas.91.14.6496 |
0.445 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2017 |
Lindsley RC, Saber W, Mar BG, Redd R, Wang T, Haagenson MD, Grauman PV, Hu ZH, Spellman SR, Lee SJ, Verneris MR, Hsu K, Fleischhauer K, Cutler C, Antin JH, ... ... Ebert BL, et al. Prognostic Mutations in Myelodysplastic Syndrome after Stem-Cell Transplantation. The New England Journal of Medicine. 376: 536-547. PMID 28177873 DOI: 10.1056/Nejmoa1611604 |
0.297 |
|
| 2019 |
Yin S, Gambe RG, Sun J, Martinez AZ, Cartun ZJ, Regis FFD, Wan Y, Fan J, Brooks AN, Herman SEM, Hacken ET, Taylor-Weiner A, Rassenti LZ, Ghia EM, Kipps TJ, ... ... Ebert BL, et al. A Murine Model of Chronic Lymphocytic Leukemia Based on B Cell-Restricted Expression of Sf3b1 Mutation and Atm Deletion. Cancer Cell. PMID 30712845 DOI: 10.1016/J.Ccell.2018.12.013 |
0.297 |
|
| 2005 |
Ebert BL, Levine RL, Wadleigh M, Brunet J, Pretz JL, Buque L, Lee SJ, Gilliland DG, Golub TR. Characterization of Distinct Molecular Signatures in Myeloproliferative Diseases with the JAK2V617F Mutation and Wild Type JAK2. Blood. 106: 119-119. DOI: 10.1182/BLOOD.V106.11.119.119 |
0.297 |
|
| 2014 |
Kowalczyk M, Tirosh I, Heckl D, Ebert B, Regev A. Single cell RNA-Seq of hematopoietic stem cells reveals a cell cycle-dependent interplay between aging and differentiation Experimental Hematology. 42: S21. DOI: 10.1016/J.Exphem.2014.07.075 |
0.296 |
|
| 2023 |
Saygin C, Zhang P, Stauber J, Aldoss I, Sperling AS, Weeks LD, Luskin MR, Knepper TC, Wanjari P, Wang P, Lager AM, Fitzpatrick C, Segal JP, Gharghabi M, Gurbuxani S, ... ... Ebert BL, et al. Acute lymphoblastic leukemia with myeloid mutations is a high-risk disease associated with clonal hematopoiesis. Blood Cancer Discovery. PMID 38150184 DOI: 10.1158/2643-3230.BCD-23-0106 |
0.294 |
|
| 2021 |
Renella R, Gagne K, Beauchamp E, Fogel J, Perlov A, Sola M, Schlaeger T, Hofmann I, Shimamura A, Ebert BL, Schmitz-Abe K, Markianos K, Murphy K, Sun L, Rockowitz S, et al. Congenital X-linked Neutropenia with Myelodysplasia and Somatic Tetraploidy due to a Germline Mutation in SEPT6. American Journal of Hematology. PMID 34677878 DOI: 10.1002/ajh.26382 |
0.294 |
|
| 2016 |
Obeng EA, Chappell RJ, Seiler M, Chen MC, Campagna DR, Schmidt PJ, Schneider RK, Lord AM, Wang L, Gambe RG, McConkey ME, Ali AM, Raza A, Yu L, Buonamici S, ... ... Ebert BL, et al. Physiologic Expression of Sf3b1(K700E) Causes Impaired Erythropoiesis, Aberrant Splicing, and Sensitivity to Therapeutic Spliceosome Modulation. Cancer Cell. 30: 404-417. PMID 27622333 DOI: 10.1016/j.ccell.2016.08.006 |
0.292 |
|
| 2015 |
Chen E, Schneider RK, Breyfogle LJ, Rosen EA, Poveromo L, Elf S, Ko A, Brumme K, Levine R, Ebert BL, Mullally A. Distinct effects of concomitant Jak2V617F expression and Tet2 loss in mice promote disease progression in myeloproliferative neoplasms. Blood. 125: 327-35. PMID 25281607 DOI: 10.1182/blood-2014-04-567024 |
0.292 |
|
| 2018 |
Lee SC, North K, Kim E, Jang E, Obeng E, Lu SX, Liu B, Inoue D, Yoshimi A, Ki M, Yeo M, Zhang XJ, Kim MK, Cho H, Chung YR, ... ... Ebert BL, et al. Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations. Cancer Cell. 34: 225-241.e8. PMID 30107174 DOI: 10.1016/J.Ccell.2018.07.003 |
0.292 |
|
| 2016 |
Lee SC, Dilai K, Obeng EA, Kim E, Micol J, Yoshimi A, Willekens C, Inoue D, Saada V, Cho H, Chung YR, Palacino J, Seiler M, Buonamici S, Smith P, ... Ebert BL, et al. Synthetic Lethal Interactions of MDS-Associated Spliceosomal Gene Mutations Identifies the Basis for Their Mutual Exclusivity Blood. 128: 961-961. DOI: 10.1182/Blood.V128.22.961.961 |
0.292 |
|
| 2015 |
Bejar R, Papaemmanuil E, Haferlach T, Garcia-Manero G, Maciejewski JP, Sekeres MA, Walter MJ, Graubert TA, Cazzola M, Malcovati L, Ogawa S, Fenaux P, Hellstrom-Lindberg E, Kern W, Boultwood J, ... ... Ebert BL, et al. Somatic Mutations in MDS Patients Are Associated with Clinical Features and Predict Prognosis Independent of the IPSS-R: Analysis of Combined Datasets from the International Working Group for Prognosis in MDS-Molecular Committee Blood. 126: 907-907. DOI: 10.1182/Blood.V126.23.907.907 |
0.291 |
|
| 2016 |
Lindsley RC, Saber W, Mar BG, Redd RA, Haagenson MD, Grauman PV, Spellman SR, Lee SJ, Wang T, Verneris MR, Hsu KC, Fleischhauer K, Cutler CS, Antin JH, Neuberg DS, ... Ebert BL, et al. Genetic Alterations Predict Outcomes in Patients with Myelodysplastic Syndrome Receiving Allogeneic Hematopoietic Stem Cell Transplantation Blood. 128: 69-69. DOI: 10.1182/Blood.V128.22.69.69 |
0.29 |
|
| 2017 |
Tothova Z, Krill-Burger JM, Popova KD, Landers CC, Sievers QL, Yudovich D, Belizaire R, Aster JC, Morgan EA, Tsherniak A, Ebert BL. Multiplex CRISPR/Cas9-Based Genome Editing in Human Hematopoietic Stem Cells Models Clonal Hematopoiesis and Myeloid Neoplasia. Cell Stem Cell. 21: 547-555.e8. PMID 28985529 DOI: 10.1016/J.Stem.2017.07.015 |
0.288 |
|
| 2014 |
Obeng EA, McConkey ME, Campagna D, Schneider RK, Chen MC, Schmidt PJ, Mullally A, Fleming MD, Ebert BL. Mutant Splicing Factor 3b Subunit 1 (SF3B1) Causes Dysregulated Erythropoiesis and a Stem Cell Disadvantage Blood. 124: 828-828. DOI: 10.1182/blood.v124.21.828.828 |
0.288 |
|
| 2023 |
Zekavat SM, Viana-Huete V, Matesanz N, Jorshery SD, Zuriaga MA, Uddin MM, Trinder M, Paruchuri K, Zorita V, Ferrer-Pérez A, Amorós-Pérez M, Kunderfranco P, Carriero R, Greco CM, Aroca-Crevillen A, ... ... Ebert BL, et al. mediated clonal hematopoiesis confers increased risk for incident atherosclerotic disease. Nature Cardiovascular Research. 2: 144-158. PMID 36949957 DOI: 10.1038/s44161-022-00206-6 |
0.287 |
|
| 2009 |
Abdel-Wahab O, Mullally A, Hedvat C, Garcia-Manero G, Patel J, Wadleigh M, Malinge S, Yao J, Kilpivaara O, Bhat R, Huberman K, Thomas S, Dolgalev I, Heguy A, Paietta E, ... ... Ebert BL, et al. Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies. Blood. 114: 144-7. PMID 19420352 DOI: 10.1182/Blood-2009-03-210039 |
0.286 |
|
| 2018 |
Fares I, Vedula RS, Vahanvaty SM, Waters CS, Luskin MR, Kumari P, McConkey M, Charles A, Copson K, Abel GA, Stone RM, Ebert BL, Lindsley RC. Bcor Mutations Cooperate with Tet2 Deficiency to Promote RAS Transformation of Mouse Hematopoietic Progenitors Blood. 132: 888-888. DOI: 10.1182/blood-2018-99-120096 |
0.286 |
|
| 2014 |
Heckl D, Kowalczyk MS, Yudovich D, Belizaire R, Puram RV, McConkey ME, Thielke A, Aster JC, Regev A, Ebert BL. Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing. Nature Biotechnology. 32: 941-6. PMID 24952903 DOI: 10.1038/Nbt.2951 |
0.285 |
|
| 2020 |
Bernard E, Nannya Y, Hasserjian RP, Devlin SM, Tuechler H, Medina-Martinez JS, Yoshizato T, Shiozawa Y, Saiki R, Malcovati L, Levine MF, Arango JE, Zhou Y, Solé F, Cargo CA, ... ... Ebert BL, et al. Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes. Nature Medicine. PMID 32747829 DOI: 10.1038/S41591-020-1008-Z |
0.284 |
|
| 2019 |
Boettcher S, Miller PG, Sharma R, McConkey M, Leventhal M, Krivtsov AV, Giacomelli AO, Wong W, Kim J, Chao S, Kurppa KJ, Yang X, Milenkowic K, Piccioni F, Root DE, ... ... Ebert BL, et al. A dominant-negative effect drives selection of missense mutations in myeloid malignancies. Science (New York, N.Y.). 365: 599-604. PMID 31395785 DOI: 10.1126/Science.Aax3649 |
0.284 |
|
| 2016 |
Sperling AS, Gibson CJ, Ebert BL. The genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemia. Nature Reviews. Cancer. PMID 27834397 DOI: 10.1038/nrc.2016.112 |
0.283 |
|
| 2023 |
Robinette ML, Weeks LD, Kramer RJ, Agrawal M, Gibson CJ, Yu Z, Sekar A, Mehta A, Niroula A, Brown JT, McDermott GC, Reshef ER, Lu JE, Liou VD, Chiou CA, ... ... Ebert BL, et al. Somatic TET2 Mutations are Associated with Giant Cell Arteritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 37909388 DOI: 10.1002/art.42738 |
0.281 |
|
| 2016 |
Doulatov S, Vo L, Macari E, Wahlster L, Taylor A, Gupta M, McGrath K, Narla A, Alter B, Gazda H, Sieff C, Agrawal S, Beggs A, Ebert B, Schlaeger T, et al. Drug discovery using induced pluripotent stem cells identifies autophagy as a therapeutic pathway for anemia Experimental Hematology. 44: S48. DOI: 10.1016/J.Exphem.2016.06.063 |
0.28 |
|
| 2014 |
Mar BG, Bullinger LB, McLean KM, Grauman PV, Harris MH, Stevenson K, Neuberg DS, Sinha AU, Sallan SE, Silverman LB, Kung AL, Lo Nigro L, Ebert BL, Armstrong SA. Mutations in epigenetic regulators including SETD2 are gained during relapse in paediatric acute lymphoblastic leukaemia. Nature Communications. 5: 3469. PMID 24662245 DOI: 10.1038/Ncomms4469 |
0.276 |
|
| 2014 |
Bejar R, Lord A, Stevenson K, Bar-Natan M, Pérez-Ladaga A, Zaneveld J, Wang H, Caughey B, Stojanov P, Getz G, Garcia-Manero G, Kantarjian H, Chen R, Stone RM, Neuberg D, ... ... Ebert BL, et al. TET2 mutations predict response to hypomethylating agents in myelodysplastic syndrome patients. Blood. 124: 2705-12. PMID 25224413 DOI: 10.1182/Blood-2014-06-582809 |
0.275 |
|
| 2014 |
Rampal R, Al-Shahrour F, Abdel-Wahab O, Patel JP, Brunel JP, Mermel CH, Bass AJ, Pretz J, Ahn J, Hricik T, Kilpivaara O, Wadleigh M, Busque L, Gilliland DG, Golub TR, ... Ebert BL, et al. Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis. Blood. 123: e123-33. PMID 24740812 DOI: 10.1182/Blood-2014-02-554634 |
0.275 |
|
| 2007 |
Fröhling S, Scholl C, Levine RL, Loriaux M, Boggon TJ, Bernard OA, Berger R, Döhner H, Döhner K, Ebert BL, Teckie S, Golub TR, Jiang J, Schittenhelm MM, Lee BH, et al. Identification of driver and passenger mutations of FLT3 by high-throughput DNA sequence analysis and functional assessment of candidate alleles. Cancer Cell. 12: 501-13. PMID 18068628 DOI: 10.1016/J.CCR.2007.11.005 |
0.274 |
|
| 2005 |
Haining WN, Ebert B, Subramanian A, Kaech S, Nadler L, Golub T, Wherry EJ. Transcriptional Mapping of T Cell Memory Reveals That Chronic Viral Infection Arrests Memory Differentiation. Blood. 106: 328-328. DOI: 10.1182/Blood.V106.11.328.328 |
0.272 |
|
| 2014 |
De Vita S, Schneider RK, Garcia M, Wood J, Gavillet M, Ebert BL, Gerbaulet A, Roers A, Levine RL, Mullally A, Williams DA. Loss of function of TET2 cooperates with constitutively active KIT in murine and human models of mastocytosis. Plos One. 9: e96209. PMID 24788138 DOI: 10.1371/Journal.Pone.0096209 |
0.272 |
|
| 2017 |
Kennedy JA, Ebert BL. Clinical Implications of Genetic Mutations in Myelodysplastic Syndrome. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 35: 968-974. PMID 28297619 DOI: 10.1200/JCO.2016.71.0806 |
0.272 |
|
| 2019 |
Fathi A, Ebert B, Motamedi M, Parikh AR, Drapkin B, Lin JJ, Saladi SV, Maus M. 10th Chabner Colloquium: Answering the Big Questions in Cancer ResearchAbstract 1 – IDH Inhibition in Acute Myeloid Leukemia: Emergence of a New Therapeutic EraAbstract 2 – Clonal HematopoiesisAbstract 3 – Epigenetic Reversal of Chemotherapy Resistance in CancersAbstract 4 – ctDNA, a Biomarker of Residual Disease and Tumor Response in Gastrointestinal CancersAbstract 5 – Cross‐Resistance in Small Cell Lung CancerAbstract 6 – RET as a Target in Lung CancerAbstract 7 – Targeting SWI/SNF‐Hippo Axis in Squamous CancersAbstract 8 – Innovations in Cell Therapy The Oncologist. 24: S1-S4. DOI: 10.1634/Theoncologist.2019-Ma-1 |
0.271 |
|
| 2020 |
Malcovati L, Stevenson K, Papaemmanuil E, Neuberg D, Bejar R, Boultwood J, Bowen DT, Campbell PJ, Ebert BL, Fenaux P, Haferlach T, Heuser M, Jansen JH, Komrokji RS, Maciejewski JP, et al. SF3B1-mutant myelodysplastic syndrome as a distinct disease subtype - A Proposal of the International Working Group for the Prognosis of Myelodysplastic Syndromes (IWG-PM). Blood. PMID 32347921 DOI: 10.1182/Blood.2020004850 |
0.271 |
|
| 2017 |
Ajore R, Raiser D, McConkey M, Jöud M, Boidol B, Mar B, Saksena G, Weinstock DM, Armstrong S, Ellis SR, Ebert BL, Nilsson B. Deletion of ribosomal protein genes is a common vulnerability in human cancer, especially in concert with TP53 mutations. Embo Molecular Medicine. PMID 28264936 DOI: 10.15252/Emmm.201606660 |
0.268 |
|
| 2017 |
Paolella B, Gibson W, Urbanski L, Alberta J, Zack T, Bandopadhayay P, Nichols C, Brown M, Lamothe R, Yu Y, Choi P, Obeng E, Wei G, Wong B, Tsherniak A, ... ... Ebert B, et al. BIOL-04. INTEGRATED COPY-NUMBER AND CANCER DEPENDENCY ANALYSIS REVEALS ALTERED SPLICEOSOME STOICHIOMETRY AS A NOVEL VULNERABILITY IN GENOMICALLY DISRUPTED CANCERS Neuro-Oncology. 19: iv4-iv4. DOI: 10.1093/Neuonc/Nox083.012 |
0.268 |
|
| 2020 |
Mouhieddine TH, Sperling AS, Redd R, Park J, Leventhal M, Gibson CJ, Manier S, Nassar AH, Capelletti M, Huynh D, Bustoros M, Sklavenitis-Pistofidis R, Tahri S, Hornburg K, Dumke H, ... ... Ebert BL, et al. Clonal hematopoiesis is associated with adverse outcomes in multiple myeloma patients undergoing transplant. Nature Communications. 11: 2996. PMID 32533060 DOI: 10.1038/s41467-020-16805-5 |
0.267 |
|
| 2019 |
Haase D, Stevenson KE, Neuberg D, Maciejewski JP, Nazha A, Sekeres MA, Ebert BL, Garcia-Manero G, Haferlach C, Haferlach T, Kern W, Ogawa S, Nagata Y, Yoshida K, Graubert TA, et al. TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups. Leukemia. PMID 30635634 DOI: 10.1038/S41375-018-0351-2 |
0.267 |
|
| 2011 |
Bejar R, Levine R, Ebert BL. Unraveling the molecular pathophysiology of myelodysplastic syndromes. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 504-15. PMID 21220588 DOI: 10.1200/Jco.2010.31.1175 |
0.267 |
|
| 2014 |
Bejar R, Stevenson KE, Caughey B, Lindsley RC, Mar BG, Stojanov P, Getz G, Steensma DP, Ritz J, Soiffer R, Antin JH, Alyea E, Armand P, Ho V, Koreth J, ... ... Ebert BL, et al. Somatic mutations predict poor outcome in patients with myelodysplastic syndrome after hematopoietic stem-cell transplantation. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 2691-8. PMID 25092778 DOI: 10.1200/Jco.2013.52.3381 |
0.266 |
|
| 2022 |
Khadka P, Reitman ZJ, Lu S, Buchan G, Gionet G, Dubois F, Carvalho DM, Shih J, Zhang S, Greenwald NF, Zack T, Shapira O, Pelton K, Hartley R, Bear H, ... ... Ebert BL, et al. PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation. Nature Communications. 13: 604. PMID 35105861 DOI: 10.1038/s41467-022-28198-8 |
0.265 |
|
| 2013 |
Wei Y, Dimicoli S, Bueso-Ramos C, Chen R, Yang H, Neuberg D, Pierce S, Jia Y, Zheng H, Wang H, Wang X, Nguyen M, Wang SA, Ebert B, Bejar R, et al. Toll-like receptor alterations in myelodysplastic syndrome. Leukemia. 27: 1832-40. PMID 23765228 DOI: 10.1038/Leu.2013.180 |
0.265 |
|
| 2011 |
Mullally A, Poveromo L, Brumme K, Al-Shahrour F, Lane SW, Shih AH, Aifantis I, Levine RL, Ebert BL. Evaluating Clonal Dominance in a Murine Knock-in Model of Jak2V617F MPN Blood. 118: 614-614. DOI: 10.1182/Blood.V118.21.614.614 |
0.264 |
|
| 2021 |
Fidler TP, Xue C, Yalcinkaya M, Hardaway B, Abramowicz S, Xiao T, Liu W, Thomas DG, Hajebrahimi MA, Pircher J, Silvestre-Roig C, Kotini AG, Luchsinger LL, Wei Y, Westerterp M, ... ... Ebert B, et al. The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis. Nature. PMID 33731931 DOI: 10.1038/s41586-021-03341-5 |
0.263 |
|
| 2015 |
Wang L, Gambe R, Fan J, Wan Y, Brooks AN, Sun J, Obeng EA, Neuberg DS, Meyerson M, Fleming MD, Ebert BL, Carrasco RD, Wu CJ. Expressionof Sf3b1- K700Ein Murine B Cells Causes Pre-mRNA Splicing and Altered B Cell Differentiation and Function Blood. 126: 366-366. DOI: 10.1182/Blood.V126.23.366.366 |
0.262 |
|
| 2010 |
Bejar R, Ebert BL. The genetic basis of myelodysplastic syndromes. Hematology/Oncology Clinics of North America. 24: 295-315. PMID 20359627 DOI: 10.1016/J.Hoc.2010.02.001 |
0.262 |
|
| 2014 |
Bejar R, Papaemmanuil E, Haferlach T, Garcia-Manero G, Maciejewski JP, Sekeres MA, Walter MJ, Graubert TA, Cazzola M, Malcovati L, Campbell PJ, Ogawa S, Boultwood J, Bowen D, Tauro S, ... ... Ebert BL, et al. TP53 Mutation Status Divides MDS Patients with Complex Karyotypes into Distinct Prognostic Risk Groups: Analysis of Combined Datasets from the International Working Group for MDS-Molecular Prognosis Committee Blood. 124: 532-532. DOI: 10.1182/Blood.V124.21.532.532 |
0.261 |
|
| 2018 |
Weinberg OK, Gibson CJ, Blonquist TM, Neuberg D, Pozdnyakova O, Kuo F, Ebert BL, Hasserjian RP. Association of mutations with morphologic dysplasia in de novo acute myeloid leukemia without 2016 WHO Classification-defined cytogenetic abnormalities. Haematologica. PMID 29326119 DOI: 10.3324/haematol.2017.181842 |
0.26 |
|
| 2013 |
Wei Y, Chen R, Dimicoli S, Bueso-Ramos C, Neuberg D, Pierce S, Wang H, Yang H, Jia Y, Zheng H, Fang Z, Nguyen M, Ganan-Gomez I, Ebert B, Levine R, et al. Global H3K4me3 genome mapping reveals alterations of innate immunity signaling and overexpression of JMJD3 in human myelodysplastic syndrome CD34+ cells Leukemia. 27: 2177-2186. PMID 23538751 DOI: 10.1038/Leu.2013.91 |
0.26 |
|
| 2006 |
Haining WN, Ebert B, Subramanian A, Kaech S, Ahmed R, Nadler L, Wherry EJ, Golub T. Su.66. Memory T-Cells in Mice and Humans Share a Common Molecular Program of Differentiation Regardless of Phenotype, Lineage Or Species Clinical Immunology. 119: S182-S183. DOI: 10.1016/J.Clim.2006.04.493 |
0.259 |
|
| 2019 |
Abdulhay NJ, Fiorini C, Verboon JM, Ludwig LS, Ulirsch JC, Zieger B, Lareau CA, Mi X, Roy A, Obeng EA, Erlacher M, Gupta N, Gabriel SB, Ebert BL, Niemeyer CM, et al. Impaired human hematopoiesis due to a cryptic intronic splicing mutation. The Journal of Experimental Medicine. PMID 30914438 DOI: 10.1084/Jem.20181625 |
0.259 |
|
| 2009 |
Raaijmakers MH, Mukherjee S, Guo S, Kobayashi T, Schoonmaker J, Aung Z, Ebert BL, Al-Shahrour F, Hasserjian RP, Vallet S, Scadden E, Lin CP, Scadden DT. Niche Induced Myelodysplasia and Secondary Hematopoietic Neoplasia Caused by Deletion of Dicer1 in Osteoprogenitor Cells. Blood. 114: 247-247. DOI: 10.1182/Blood.V114.22.247.247 |
0.256 |
|
| 2018 |
Tothova Z, Krill-Burger JM, Day DS, Haydu JE, Abraham BJ, Landers CC, Malolepsza E, Hartigan CR, Holmes A, Donahue M, Popova KD, Koochaki S, Rivera J, Seiler M, Hnisz D, ... ... Ebert BL, et al. STAG2 Mutations Alter Cohesin Ring Function and Provide Therapeutic Vulnerabilities in Acute Myeloid Leukemia Blood. 132: 940-940. DOI: 10.1182/Blood-2018-99-117480 |
0.256 |
|
| 2020 |
Tothova Z, Valton AL, Gorelov R, Vallurupalli M, Krill-Burger JM, Holmes A, Landers CC, Haydu JE, Malolepsza E, Hartigan CR, Donahue M, Popova KD, Koochaki SHJ, Venev SV, Rivera JF, ... ... Ebert BL, et al. Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML. Jci Insight. PMID 33351783 DOI: 10.1172/jci.insight.142149 |
0.256 |
|
| 2020 |
Zekavat SM, Lin SH, Bick AG, Liu A, Paruchuri K, Uddin MM, Ye Y, Yu Z, Liu X, Kamatani Y, Pirruccello JP, Pampana A, Loh PR, Kohli P, McCarroll SA, ... ... Ebert BL, et al. Hematopoietic mosaic chromosomal alterations and risk for infection among 767,891 individuals without blood cancer. Medrxiv : the Preprint Server For Health Sciences. PMID 33236019 DOI: 10.1101/2020.11.12.20230821 |
0.255 |
|
| 2013 |
Tothova Z, Steensma DP, Ebert BL. New strategies in myelodysplastic syndromes: application of molecular diagnostics to clinical practice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 1637-43. PMID 23329810 DOI: 10.1158/1078-0432.CCR-12-1251 |
0.255 |
|
| 2020 |
Natarajan P, Zekavat S, Lin SH, Bick A, Liu A, Paruchuri K, Uddin MM, Ye Y, Yu Z, Liu X, Kamatani Y, Pirruccello J, Pampana A, Loh PR, Kohli P, ... ... Ebert B, et al. Hematopoietic mosaic chromosomal alterations and risk for infection among 767,891 individuals without blood cancer. Research Square. PMID 33236004 DOI: 10.21203/rs.3.rs-100817/v1 |
0.255 |
|
| 2010 |
Quigley M, Pereyra F, Nilsson B, Porichis F, Fonseca C, Eichbaum Q, Julg B, Jesneck JL, Brosnahan K, Imam S, Russell K, Toth I, Piechocka-Trocha A, Dolfi D, Angelosanto J, ... ... Ebert B, et al. Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF. Nature Medicine. 16: 1147-51. PMID 20890291 DOI: 10.1038/Nm.2232 |
0.254 |
|
| 2009 |
Ebert BL. Ribosome Dysfunction and Ineffective Hematopoiesis. Blood. 114: SCI-11-SCI-11. DOI: 10.1182/blood.v114.22.sci-11.sci-11 |
0.253 |
|
| 2020 |
Sallman DA, McLemore AF, Aldrich AL, Komrokji RS, McGraw KL, Dhawan A, Geyer S, Hou HA, Eksioglu EA, Sullivan A, Warren S, MacBeth KJ, Meggendorfer M, Haferlach T, Boettcher S, ... Ebert BL, et al. TP53 mutations in myelodysplastic syndromes and secondary AML confer an immunosuppressive phenotype. Blood. PMID 32730593 DOI: 10.1182/Blood.2020006158 |
0.253 |
|
| 2013 |
Murphy DM, Bejar R, Stevenson K, Neuberg D, Shi Y, Cubrich C, Richardson K, Eastlake P, Garcia-Manero G, Kantarjian H, Ebert BL, Mike Makrigiorgos G. NRAS mutations with low allele burden have independent prognostic significance for patients with lower risk myelodysplastic syndromes. Leukemia. 27: 2077-81. PMID 23708912 DOI: 10.1038/Leu.2013.160 |
0.253 |
|
| 2010 |
Mullally A, Lane SW, Poveromo L, Al-Shahrour F, Kutok J, Ebert BL. Characterizing the Disease-Initiating Cell Population In a Murine Model of Jak2V617F+ Myeloproliferative Neoplasm Blood. 116: 317-317. DOI: 10.1182/blood.v116.21.317.317 |
0.251 |
|
| 2018 |
Yin M, Chung YJ, Lindsley RC, Zhu Y, Walker RL, Ebert BL, Meltzer PS, Aplan PD. Engineered Bcor Mutations Lead to Acute Lymphoblastic Leukemia of Progenitor B-1 Lymphocyte Origin in a Sensitized Background Blood. 132: 1331-1331. DOI: 10.1182/Blood-2018-99-115388 |
0.251 |
|
| 2013 |
Lindsley RC, Ebert BL. Molecular pathophysiology of myelodysplastic syndromes. Annual Review of Pathology. 8: 21-47. PMID 22934674 DOI: 10.1146/annurev-pathol-011811-132436 |
0.25 |
|
| 2006 |
Haining WN, Ebert B, Subramanian A, Wherry EJ, Evans J, Mak R, Rivoli S, Angelosanto J, Pretz J, Kaech S, Ahmed R, Nadler LM, Golub TR. All Memory Lymphocytes Share a Common Differentiation Program. Blood. 108: 865-865. DOI: 10.1182/Blood.V108.11.865.865 |
0.249 |
|
| 2023 |
Pasupuleti SK, Ramdas B, Burns SS, Palam LR, Kanumuri R, Kumar R, Pandhiri TR, Dave U, Yellapu NK, Zhou X, Zhang C, Sandusky GE, Yu Z, Honigberg MC, Bick AG, ... ... Ebert BL, et al. Obesity induced inflammation exacerbates clonal hematopoiesis. The Journal of Clinical Investigation. PMID 37071471 DOI: 10.1172/JCI163968 |
0.249 |
|
| 2013 |
De Vita S, Mullally A, Schneider-Kramann R, Garcia M, Ebert B, Gerbaulet A, Levine R, Williams D. Cooperation of KITD816V and TET2 loss of function in the pathogenesis of systemic mastocytosis and associated hematological malignancies Experimental Hematology. 41: S15. DOI: 10.1016/J.Exphem.2013.05.057 |
0.246 |
|
| 2005 |
Levine RL, Wadleigh M, Cools J, Ebert BL, Wernig G, Huntly BJ, Boggon TJ, Wlodarska I, Clark JJ, Moore S, Adelsperger J, Koo S, Lee JC, Gabriel S, Mercher T, et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell. 7: 387-97. PMID 15837627 DOI: 10.1016/J.Ccr.2005.03.023 |
0.246 |
|
| 2010 |
Raaijmakers MH, Mukherjee S, Guo S, Zhang S, Kobayashi T, Schoonmaker JA, Ebert BL, Al-Shahrour F, Hasserjian RP, Scadden EO, Aung Z, Matza M, Merkenschlager M, Lin C, Rommens JM, et al. Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia. Nature. 464: 852-7. PMID 20305640 DOI: 10.1038/Nature08851 |
0.246 |
|
| 2019 |
Jasra S, Giricz O, Zeig-Owens R, Goldfarb D, Barreto-Galvez A, Pradhan K, Chen J, Choudhary GS, Aluri S, Bhagat TD, Shastri A, Thiruthuvanathan V, Goto H, Gerhardt J, Gordon S, ... ... Ebert BL, et al. High Burden of Clonal Hematopoiesis in First Responders Exposed to the World Trade Center Disaster Blood. 134: 3720-3720. DOI: 10.1182/Blood-2019-129276 |
0.245 |
|
| 2023 |
Miller PG, Sperling AS, Mayerhofer C, McConkey M, Ellegast JM, Da Silva C, Cohen DN, Wang C, Sharda A, Yan N, Saha S, Schluter C, Schechter IA, Słabicki M, Sandoval B, ... ... Ebert BL, et al. PPM1D modulates hematopoietic cell fitness and response to DNA damage and is a therapeutic target in myeloid malignancy. Blood. PMID 37595362 DOI: 10.1182/blood.2023020331 |
0.245 |
|
| 2012 |
Mullally A, Poveromo L, Schneider RK, Al-Shahrour F, Lane SW, Ebert BL. Distinct roles for long-term hematopoietic stem cells and erythroid precursor cells in a murine model of Jak2V617F-mediated polycythemia vera. Blood. 120: 166-72. PMID 22627765 DOI: 10.1182/blood-2012-01-402396 |
0.245 |
|
| 2013 |
Perez-Ladaga A, Caughey B, Xie H, Orkin SH, Sykes DB, Ebert BL, Bejar R. Functional Defects In Neutrophils Derived From Ezh2 Null Mice Blood. 122: 1556-1556. DOI: 10.1182/Blood.V122.21.1556.1556 |
0.245 |
|
| 2018 |
Mouhieddine TH, Park J, Redd RA, Gibson CJ, Manier S, Nassar AH, Capelletti M, Huynh D, Bustoros M, Sklavenitis-Pistofidis R, Hornburg K, Dumke H, Itani MM, Boehner CJ, Liu C, ... ... Ebert BL, et al. The Role of Clonal Hematopoiesis of Indeterminate Potential (CHIP) in Multiple Myeloma: Immunomodulator Maintenance Post Autologous Stem Cell Transplant (ASCT) Predicts Better Outcome Blood. 132: 749-749. DOI: 10.1182/BLOOD-2018-99-113059 |
0.245 |
|
| 2018 |
Abdulhay N, Verboon J, Ulirsch J, Zieger B, Mi X, Obeng E, Erlacher M, Gupta N, Gabriel S, Ebert B, Niemeyer C, Khoriaty R, Ancliff P, Gazda H, Wlodarski M, et al. A Cryptic Intronic GATA1 Splicing Mutation Provides Insights Into Human Hematopoietic Differentiation Experimental Hematology. 64: S53. DOI: 10.1016/J.Exphem.2018.06.185 |
0.244 |
|
| 2022 |
Woll PS, Yoshizato T, Hellström-Lindberg E, Fioretos T, Ebert BL, Jacobsen SEW. Targeting stem cells in myelodysplastic syndromes and acute myeloid leukemia. Journal of Internal Medicine. 292: 262-277. PMID 35822488 DOI: 10.1111/joim.13535 |
0.244 |
|
| 2013 |
Bejar R, Murphy D, Stevenson K, Neuberg D, Shi Y, Cubrich C, Richardson K, Eastlake P, Garcia-Manero G, Kantarjian H, Ebert B, Makrigiorgos G. P-103 Occult NRAS mutations with very low allele burden have independent prognostic significance in lower-risk myelodysplastic syndromes Leukemia Research. 37: S68-S69. DOI: 10.1016/S0145-2126(13)70151-6 |
0.243 |
|
| 2024 |
Sirenko M, Bernard E, Creignou M, Domenico D, Farina A, Arango Ossa JE, Kosmider O, Hasserjian RP, Jädersten M, Germing U, Sanz GF, van de Loosdrecht AA, Gurnari C, Follo MY, Thol FR, ... ... Ebert BL, et al. Molecular and clinical presentation of UBA1-mutated myelodysplastic syndromes. Blood. PMID 38687605 DOI: 10.1182/blood.2023023723 |
0.243 |
|
| 2015 |
Song C, Castellanos-Rizaldos E, Bejar R, Ebert BL, Makrigiorgos GM. DMSO Increases Mutation Scanning Detection Sensitivity of High-Resolution Melting in Clinical Samples. Clinical Chemistry. PMID 26432802 DOI: 10.1373/Clinchem.2015.245357 |
0.242 |
|
| 2017 |
Weinberg OK, Gibson CJ, Blonquist TM, Neuberg D, Pozdnyakova O, Kuo F, Ebert BL, Hasserjian RP. NPM1 mutation but not RUNX1 mutation or multilineage dysplasia defines a prognostic subgroup within de novo acute myeloid leukemia lacking recurrent cytogenetic abnormalities in the revised 2016 WHO Classification. American Journal of Hematology. PMID 28370403 DOI: 10.1002/ajh.24739 |
0.242 |
|
| 2003 |
Ortner MA, Ebert B, Hein E, Zumbusch K, Nolte D, Sukowski U, Weber-Eibel J, Fleige B, Dietel M, Stolte M, Oberhuber G, Porschen R, Klump B, Hörtnagl H, Lochs H, et al. Time gated fluorescence spectroscopy in Barrett's oesophagus. Gut. 52: 28-33. PMID 12477755 DOI: 10.1136/Gut.52.1.28 |
0.241 |
|
| 2011 |
Bejar R, Stevenson K, Abdel-Wahab O, Galili N, Nilsson B, Garcia-Manero G, Kantarjian H, Raza A, Levine RL, Neuberg D, Ebert BL. Clinical effect of point mutations in myelodysplastic syndromes. The New England Journal of Medicine. 364: 2496-506. PMID 21714648 DOI: 10.1056/Nejmoa1013343 |
0.24 |
|
| 2022 |
Jasra S, Giricz O, Zeig-Owens R, Pradhan K, Goldfarb DG, Barreto-Galvez A, Silver AJ, Chen J, Sahu S, Gordon-Mitchell S, Choudhary GS, Aluri S, Bhagat TD, Shastri A, Bejan CA, ... ... Ebert BL, et al. High burden of clonal hematopoiesis in first responders exposed to the World Trade Center disaster. Nature Medicine. PMID 35256801 DOI: 10.1038/s41591-022-01708-3 |
0.24 |
|
| 2020 |
Hasserjian RP, Steensma DP, Graubert TA, Ebert BL. Clonal Hematopoiesis and Measurable Residual Disease Assessment in Acute Myeloid Leukemia. Blood. PMID 32232484 DOI: 10.1182/Blood.2019004770 |
0.24 |
|
| 2021 |
Bhattacharya R, Zekavat SM, Uddin MM, Pirruccello J, Niroula A, Gibson C, Griffin GK, Libby P, Ebert BL, Bick A, Natarajan P. Association of Diet Quality With Prevalence of Clonal Hematopoiesis and Adverse Cardiovascular Events. Jama Cardiology. PMID 34106216 DOI: 10.1001/jamacardio.2021.1678 |
0.24 |
|
| 2023 |
Carter BZ, Mak PY, Muftuoglu M, Tao W, Baozhen K, Pei J, Bedoy AD, Ostermann LB, Nishida Y, Isqandarova S, Sobieski M, Nguyen N, Powell RT, Martinez-Moczyemba M, Stephan C, ... ... Ebert BL, et al. Epichaperome inhibition targets TP53-mutant AML and AML stem/progenitor cells. Blood. PMID 37339579 DOI: 10.1182/blood.2022019047 |
0.239 |
|
| 2021 |
Belizaire R, Koochaki SHJ, Udeshi ND, Vedder A, Sun L, Svinkina T, Hartigan C, McConkey ME, Kovalcik V, Bizuayehu A, Stanclift C, Schenone M, Carr SA, Padron E, Ebert BL. CBL mutations drive PI3K/AKT signaling via increased interaction with LYN and PIK3R1. Blood. PMID 33512474 DOI: 10.1182/blood.2020006528 |
0.239 |
|
| 2015 |
Lindsley RC, Mar BG, Mazzola E, Grauman PV, Shareef S, Allen SL, Pigneux A, Wetzler M, Stuart RK, Erba HP, Damon LE, Powell BL, Lindeman N, Steensma DP, Wadleigh M, ... ... Ebert BL, et al. Acute myeloid leukemia ontogeny is defined by distinct somatic mutations. Blood. 125: 1367-76. PMID 25550361 DOI: 10.1182/Blood-2014-11-610543 |
0.239 |
|
| 2022 |
Sperling AS, Guerra VA, Kennedy JA, Yan Y, Hsu JI, Wang F, Nguyen AT, Miller PG, McConkey ME, Quevedo Barrios VA, Furudate K, Zhang L, Kanagal-Shamanna R, Zhang J, Little LD, ... ... Ebert BL, et al. Lenalidomide promotes the development of TP53-mutated therapy-related myeloid neoplasms. Blood. PMID 35512188 DOI: 10.1182/blood.2021014956 |
0.238 |
|
| 2009 |
Kilpivaara O, Mukherjee S, Schram AM, Wadleigh M, Mullally A, Ebert BL, Bass A, Marubayashi S, Heguy A, Garcia-Manero G, Kantarjian H, Offit K, Stone RM, Gilliland DG, Klein RJ, et al. A germline JAK2 SNP is associated with predisposition to the development of JAK2(V617F)-positive myeloproliferative neoplasms. Nature Genetics. 41: 455-9. PMID 19287384 DOI: 10.1038/ng.342 |
0.238 |
|
| 2009 |
Eppert K, Takenaka K, Nilsson B, Lechman ER, Ling V, Beyene J, Canty AJ, Danska JS, Minden MD, Golub TR, Ebert BL, Dick JE. Leukemic and Normal Stem Cell Transcriptional Signatures Determined by Functional Assays Are Predictive of the Overall Survival of AML Patients. Blood. 114: 389-389. DOI: 10.1182/Blood.V114.22.389.389 |
0.238 |
|
| 2023 |
de Matos Simoes R, Shirasaki R, Downey-Kopyscinski SL, Matthews GM, Barwick BG, Gupta VA, Dupéré-Richer D, Yamano S, Hu Y, Sheffer M, Dhimolea E, Dashevsky O, Gandolfi S, Ishiguro K, Meyers RM, ... ... Ebert BL, et al. Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias. Nature Cancer. 4: 754-773. PMID 37237081 DOI: 10.1038/s43018-023-00550-x |
0.236 |
|
| 2019 |
DeZern AE, Malcovati L, Ebert BL. CHIP, CCUS, and Other Acronyms: Definition, Implications, and Impact on Practice. American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting. 39: 400-410. PMID 31099654 DOI: 10.1200/EDBK_239083 |
0.236 |
|
| 2020 |
Bolton KL, Ptashkin RN, Gao T, Braunstein L, Devlin SM, Kelly D, Patel M, Berthon A, Syed A, Yabe M, Coombs CC, Caltabellotta NM, Walsh M, Offit K, Stadler Z, ... ... Ebert BL, et al. Cancer therapy shapes the fitness landscape of clonal hematopoiesis. Nature Genetics. PMID 33106634 DOI: 10.1038/s41588-020-00710-0 |
0.235 |
|
| 2015 |
Buonamici S, Darman R, Perino S, Agrawal A, Peng S, Seiler M, Lim KH, Bhavsar EB, Feala J, Obeng EA, Bailey S, Chan B, Fekkes P, Keaney GF, Kumar P, ... ... Ebert BL, et al. Heterozygous Hotspot SF3B1 Mutations Found in Myelodysplastic Syndromes Downregulate Genes Involved in Differentiation of Erythroid Cells Blood. 126: 1643-1643. DOI: 10.1182/Blood.V126.23.1643.1643 |
0.232 |
|
| 2013 |
Chen E, Breyfogle LJ, Schneider RK, Poveromo L, Levine RL, Ebert BL, Mullally A. Tet2 Loss Accelerates The Myeloproliferative Neoplasm (MPN) Phenotype Of Jak2V617F Knockin Mice But Is Insufficient To Cause Leukemic Transformation Blood. 122: 4095-4095. DOI: 10.1182/blood.v122.21.4095.4095 |
0.231 |
|
| 2015 |
Ugrankar R, Berglund E, Akdemir F, Tran C, Kim MS, Noh J, Schneider R, Ebert B, Graff JM. Drosophila glucome screening identifies Ck1alpha as a regulator of mammalian glucose metabolism. Nature Communications. 6: 7102. PMID 25994086 DOI: 10.1038/Ncomms8102 |
0.231 |
|
| 2019 |
Yin M, Chung YJ, Lindsley RC, Walker RL, Zhu YJ, Ebert BL, Meltzer PS, Aplan PD. Engineered Bcor mutations lead to acute leukemia of progenitor B-1 lymphocyte origin in a sensitized background. Blood. PMID 30992267 DOI: 10.1182/Blood.2018864173 |
0.231 |
|
| 2019 |
McGraw KL, Cheng CH, Chen YA, Hou HA, Nilsson B, Genovese G, Cluzeau T, Pellagatti A, Przychodzen BP, Mallo M, Arenillas L, Mohamedali A, Adès L, Sallman DA, Padron E, ... ... Ebert BL, et al. Non-del(5q) myelodysplastic syndromes-associated loci detected by SNP-array genome-wide association meta-analysis. Blood Advances. 3: 3579-3589. PMID 31738830 DOI: 10.1182/Bloodadvances.2019000922 |
0.23 |
|
| 2020 |
Ramakrishnan R, Peña-Martínez P, Agarwal P, Rodriguez-Zabala M, Chapellier M, Högberg C, Eriksson M, Yudovich D, Shah M, Ehinger M, Nilsson B, Larsson J, Hagström-Andersson A, Ebert BL, Bhatia R, et al. CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia. Cell Reports. 31: 107684. PMID 32460032 DOI: 10.1016/j.celrep.2020.107684 |
0.23 |
|
| 2015 |
Joyce CE, McGuinness M, Schneider RK, Fleming MD, Campagna DR, Schmidt PJ, Ebert BL, Novina CD, Sieff CA. A Novel Conditional Knockout of the Diamond Blackfan Anemia Gene Rpl11 Shows Failure of Erythropoiesis, a Marked Increase in BFU-E Progenitors By Phenotype That Proliferate Poorly in Culture, and Activation of p53 Target Genes Blood. 126: 1205-1205. DOI: 10.1182/Blood.V126.23.1205.1205 |
0.229 |
|
| 2012 |
Park SM, Deering R, Lu Y, Tivnan P, Shenoy V, Lianoglou S, Al-Shahrour F, Leslie C, Ebert BL, Lengner C, Daley GQ, Kharas MG. Direct RNA Target Analysis Identifies Signatures That Define Msi2's Role in Sustaining HSC Cell Fate. Blood. 120: 2324-2324. DOI: 10.1182/Blood.V120.21.2324.2324 |
0.227 |
|
| 2010 |
Kharas MG, Lengner CJ, Al-Shahrour F, Bullinger L, Ball B, Zaidi S, Morgan K, Tam W, Paktinat M, Okabe R, Gozo M, Einhorn W, Lane SW, Scholl C, Fröhling S, ... ... Ebert BL, et al. Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia. Nature Medicine. 16: 903-8. PMID 20616797 DOI: 10.1038/Nm.2187 |
0.226 |
|
| 2005 |
Ebert BL, Lee MM, Pretz JL, Subramanian A, Mak R, Golub TR, Sieff CA. An RNA interference model of RPS19 deficiency in Diamond-Blackfan anemia recapitulates defective hematopoiesis and rescue by dexamethasone: identification of dexamethasone-responsive genes by microarray. Blood. 105: 4620-6. PMID 15755903 DOI: 10.1182/Blood-2004-08-3313 |
0.226 |
|
| 2008 |
Lin X, Buzzai M, Levine RL, Berkofsky-Fessler W, Zhang W, Ebert BL, Gilliland DG, Licht JD. NFIB: A Gene Consistently Upregulated in MPD and Frequently Co-Amplified with JAK2V617F Augments Growth of Erythropoietin Dependent Cells Blood. 112: 3727-3727. DOI: 10.1182/blood.v112.11.3727.3727 |
0.226 |
|
| 2012 |
Mullally A, Bruedigam C, Heckl D, Poveromo L, Heidel FH, Hill G, Ebert BL, Lane SW. Depletion of Jak2V617F MPN Stem Cells by IFNα in a Murine Model of Polycythemia Vera Blood. 120: 806-806. DOI: 10.1182/blood.v120.21.806.806 |
0.225 |
|
| 2019 |
Belizaire R, Koochaki S, Udeshi N, Vedder A, Sun L, Schenone M, Carr S, Padron E, Ebert BL. Oncogenic Mechanisms of CBL E3 Ubiquitin Ligase Mutations in Myeloid Malignancies Blood. 134: 563-563. DOI: 10.1182/Blood-2019-122503 |
0.224 |
|
| 2017 |
Doulatov S, Vo LT, Macari ER, Wahlster L, Kinney MA, Taylor AM, Barragan J, Gupta M, McGrath K, Lee HY, Humphries JM, DeVine A, Narla A, Alter BP, Beggs AH, ... ... Ebert BL, et al. Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors. Science Translational Medicine. 9. PMID 28179501 DOI: 10.1126/Scitranslmed.Aah5645 |
0.224 |
|
| 2003 |
Ebert B, Shaffer K, Rennke H. Some unusual paraneoplastic syndromes: Case 4. Paraneoplastic nephrotic syndrome in a patient with lung cancer Journal of Clinical Oncology. 21: 2624-2625. PMID 12829687 DOI: 10.1200/Jco.2003.11.021 |
0.224 |
|
| 2012 |
Chattopadhyay S, Stewart AL, Mukherjee S, Huang C, Hartwell KA, Miller PG, Carmody L, Yusuf RZ, Sykes DB, Vallet S, Santo L, Cirstea DD, Hideshima T, Dancik V, Cheah J, ... ... Ebert BL, et al. Niche-Based Screening Identifies Novel Small Molecules That Overcome Stromal Effects in Multiple Myeloma Blood. 120: 571-571. DOI: 10.1182/Blood.V120.21.571.571 |
0.222 |
|
| 2006 |
Thomas A, Fischer T, Frey H, Ohlinger R, Grunwald S, Blohmer JU, Winzer KJ, Weber S, Kristiansen G, Ebert B, Kümmel S. Real-time elastography - An advanced method of ultrasound: First results in 108 patients with breast lesions Ultrasound in Obstetrics and Gynecology. 28: 335-340. PMID 16909438 DOI: 10.1002/Uog.2823 |
0.221 |
|
| 2017 |
Vu LP, Prieto C, Amin EM, Chhangawala S, Krivtsov A, Calvo-Vidal MN, Chou T, Chow A, Minuesa G, Park SM, Barlowe TS, Taggart J, Tivnan P, Deering RP, Chu LP, ... ... Ebert BL, et al. Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells. Nature Genetics. PMID 28436985 DOI: 10.1038/Ng.3854 |
0.221 |
|
| 2012 |
Ashton JM, Balys M, Neering SJ, Hassane DC, Cowley G, Root DE, Miller PG, Ebert BL, McMurray HR, Land H, Jordan CT. Gene sets identified with oncogene cooperativity analysis regulate in vivo growth and survival of leukemia stem cells. Cell Stem Cell. 11: 359-72. PMID 22863534 DOI: 10.1016/J.Stem.2012.05.024 |
0.221 |
|
| 2020 |
Taylor AM, Macari ER, Chan IT, Blair MC, Doulatov S, Vo LT, Raiser DM, Siva K, Basak A, Pirouz M, Shah AN, McGrath K, Humphries JM, Stillman E, Alter BP, ... ... Ebert BL, et al. Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia. Science Translational Medicine. 12. PMID 33087503 DOI: 10.1126/scitranslmed.abb5831 |
0.22 |
|
| 2015 |
Mar BG, Kahn J, Zon RL, Grauman PV, Boettger K, Chu SH, Armstrong SA, Ebert BL. SETD2 Heterozygous Loss in Leukemia Leads to Chemotherapy Resistance through Attenuation of the DNA Damage Response Blood. 126: 2626-2626. DOI: 10.1182/Blood.V126.23.2626.2626 |
0.22 |
|
| 2011 |
Kharas MG, Lengner C, Al-Shahrour F, Ebert BL, Daley GQ. Msi2 Maintains Normal Hematopoietic Stem Cell Self-Renewal Blood. 118: 222-222. DOI: 10.1182/Blood.V118.21.222.222 |
0.22 |
|
| 2017 |
Paolella BR, Gibson WJ, Urbanski LM, Alberta JA, Zack TI, Bandopadhayay P, Nichols CA, Agarwalla PK, Brown MS, Lamothe R, Yu Y, Choi PS, Obeng EA, Heckl D, Wei G, ... ... Ebert BL, et al. Copy-number and gene dependency analysis reveals partial copy loss of wild-type SF3B1 as a novel cancer vulnerability. Elife. 6. PMID 28177281 DOI: 10.7554/Elife.23268 |
0.22 |
|
| 2015 |
Obeng EA, Ebert BL. Charting the "Splice" Routes to MDS. Cancer Cell. 27: 607-9. PMID 25965565 DOI: 10.1016/j.ccell.2015.04.016 |
0.219 |
|
| 2014 |
Lord AM, Clement K, Schneider RK, Marie M, Chen MC, Levine RL, Mullally A, Galili N, Ali AM, Raza A, Bejar R, Meissner A, Ebert BL. Loss of TET2 Function in Myelodysplastic Syndrome Results in Intragenic Hypermethylation and Alterations in mRNA Splicing Blood. 124: 775-775. DOI: 10.1182/Blood.V124.21.775.775 |
0.219 |
|
| 2014 |
Buonamici S, Perino S, Lim KH, Feala J, Obeng EA, Aicher M, Aird D, Bailey S, Berkenblit A, Chan B, Erik C, Corson L, Darman R, Fekkes P, Furman RR, ... ... Ebert BL, et al. Cancer-Associated Mutations in SF3B1 Exhibit Neomorphic Splicing Activity and Block Erythroid Differentiation Blood. 124: 4615-4615. DOI: 10.1182/Blood.V124.21.4615.4615 |
0.219 |
|
| 2013 |
Mullally A, Bruedigam C, Poveromo L, Heidel FH, Purdon A, Vu T, Austin R, Heckl D, Breyfogle LJ, Kuhn CP, Kalaitzidis D, Armstrong SA, Williams DA, Hill GR, Ebert BL, et al. Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-α in a murine model of polycythemia vera. Blood. 121: 3692-702. PMID 23487027 DOI: 10.1182/Blood-2012-05-432989 |
0.219 |
|
| 2016 |
Puram RV, Kowalczyk MS, de Boer CG, Schneider RK, Miller PG, McConkey M, Tothova Z, Tejero H, Heckl D, Järås M, Chen MC, Li H, Tamayo A, Cowley GS, Rozenblatt-Rosen O, ... ... Ebert BL, et al. Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML. Cell. 165: 303-316. PMID 27058663 DOI: 10.1016/j.cell.2016.03.015 |
0.218 |
|
| 2019 |
Nandakumar SK, McFarland SK, Mateyka LM, Lareau CA, Ulirsch JC, Ludwig LS, Agarwal G, Engreitz JM, Przychodzen B, McConkey M, Cowley GS, Doench JG, Maciejewski JP, Ebert BL, Root DE, et al. Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis. Elife. 8. PMID 31070582 DOI: 10.7554/Elife.44080 |
0.218 |
|
| 2018 |
McGraw KL, Cheng C, Chen YA, Hou H, Genovese G, Cluzeau T, Pellagatti A, Przychodzen B, Mallo M, Leonor A, Mohamedali AM, Ades L, Sallman DA, Padron E, Sokol L, ... ... Ebert BL, et al. SNP-Array Genome Wide Association Study Meta-Analysis Identifies Innate Immune Susceptibility Loci Associated with Non-Del(5q) Myelodysplastic Syndromes Predisposition Blood. 132: 107-107. DOI: 10.1182/Blood-2018-99-118747 |
0.218 |
|
| 2015 |
Macari ER, Taylor A, Raiser D, Siva K, McGrath K, Humphries JM, Flygare J, Ebert BL, Zon LI. Calmodulin Inhibition Rescues the Effects of Ribosomal Protein Deficiency in in Vitro and In Vivo Diamond Blackfan Anemia Models Blood. 126: 672-672. DOI: 10.1182/Blood.V126.23.672.672 |
0.218 |
|
| 2015 |
Perez-Ladaga A, Xie H, Orkin SH, Sykes DB, Ebert BL, Bejar R. Neutrophils Derived from Ezh2 -/- Progenitor Cells Demonstrate Aberrant Erythroid Lineage Gene Expression Blood. 126: 4112-4112. DOI: 10.1182/Blood.V126.23.4112.4112 |
0.218 |
|
| 2017 |
Mar BG, Chu SH, Kahn JD, Krivstov AV, Koche R, Castellano CA, Kotlier JL, Zon RL, McConkey ME, Chabon J, Chappell R, Grauman PV, Hsieh JJ, Armstrong SA, Ebert BL. SETD2 alterations impair DNA damage recognition and lead to resistance to chemotherapy in leukemia. Blood. PMID 29018079 DOI: 10.1182/Blood-2017-03-775569 |
0.218 |
|
| 2016 |
Wolach O, Sellar RS, Martinod K, McConkey ME, Silver AJ, Chappell R, Stone RM, Wadleigh M, Steensma DP, DeAngelo DJ, Galinsky I, Schneider RK, Padera RF, Mullally A, Wagner DD, ... Ebert BL, et al. Thrombosis in Myeloproliferative Neoplasms Is Linked to Increased Neutrophil Extracellular Trap (NET) Formation Blood. 128: 633-633. DOI: 10.1182/Blood.V128.22.633.633 |
0.218 |
|
| 2012 |
Järås M, Miller PG, Chu L, Schneider RK, Puram RV, Al-Shahrour F, Fink E, Hartwell KA, McConkey M, Cowley G, Mullally A, Kharas MG, Ebert BL. Casein Kinase 1 Alpha Maintains Normal and Leukemic Stem Cells by Regulating p53 Activity Blood. 120: 209-209. DOI: 10.1182/blood.v120.21.209.209 |
0.218 |
|
| 2019 |
Meyer T, Jahn N, Lindner S, Röhner L, Dolnik A, Weber D, Scheffold A, Köpff S, Paschka P, Gaidzik VI, Heckl D, Wiese S, Ebert BL, Döhner H, Bullinger L, et al. Functional characterization of BRCC3 mutations in acute myeloid leukemia with t(8;21)(q22;q22.1). Leukemia. PMID 31576005 DOI: 10.1038/s41375-019-0578-6 |
0.217 |
|
| 2023 |
Belizaire R, Wong WJ, Robinette ML, Ebert BL. Clonal haematopoiesis and dysregulation of the immune system. Nature Reviews. Immunology. PMID 36941354 DOI: 10.1038/s41577-023-00843-3 |
0.216 |
|
| 2012 |
Bejar R, Stevenson KE, Caughey BA, Abdel-Wahab O, Steensma DP, Galili N, Raza A, Kantarjian H, Levine RL, Neuberg D, Garcia-Manero G, Ebert BL. Validation of a prognostic model and the impact of mutations in patients with lower-risk myelodysplastic syndromes. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 3376-82. PMID 22869879 DOI: 10.1200/Jco.2011.40.7379 |
0.216 |
|
| 2002 |
Ortner M-, Zumbusch K, Liebetruth J, Ebert B, Fleige B, Dietel M, Lochs H. Is Topical δ-Aminolevulinic Acid Adequate for Photodynamic Therapy in Barrett’s Esophagus? A Pilot Study Endoscopy. 34: 611-616. PMID 12173080 DOI: 10.1055/S-2002-33247 |
0.215 |
|
| 2012 |
Yusuf RZ, Acharya SS, Yu VW, Saez B, Cobert JM, Doench J, Bullinger L, S'aulis D, Lee D, Palchaudhuri R, Uzosike AC, Duvet M, Logan DJ, Das S, Cook CM, ... ... Ebert BL, et al. Aldehyde Dehydrogenase 3a2 (Aldh3a2) Represents a Distinct Metabolic Vulnerability in MLL-AF9 AML Leukemia Initiating Cells Blood. 120: 208-208. DOI: 10.1182/Blood.V120.21.208.208 |
0.215 |
|
| 2014 |
Ebert B. Targeting ubiquitin ligases for the treatment of hematologic malignancies Experimental Hematology. 42: S10. DOI: 10.1016/J.Exphem.2014.07.032 |
0.215 |
|
| 2016 |
Matthews GM, De Matos Simoes R, Hu Y, Sheffer M, Dhimolea E, Hengeveld PJ, Bariteau MA, Glassner B, Sievers Q, Ebert BL, Gandolfi S, Awate P, Tang H, Vazquez F, Culhane A, et al. Characterization of Lineage Vs. Context-Dependent Essential Genes in Multiple Myeloma Using Crispr/Cas9 Genome Editing Blood. 128: 119-119. DOI: 10.1182/Blood.V128.22.119.119 |
0.214 |
|
| 2015 |
Chattopadhyay S, Stewart AL, Mukherjee S, Huang C, Hartwell KA, Miller PG, Subramanian R, Carmody LC, Yusuf RZ, Sykes DB, Paulk J, Vetere A, Vallet S, Santo L, Cirstea DD, ... ... Ebert BL, et al. Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors. Cell Reports. PMID 25660025 DOI: 10.1016/J.Celrep.2015.01.017 |
0.213 |
|
| 2023 |
Weeks LD, Ebert BL. Causes and Consequences of Clonal Hematopoiesis. Blood. PMID 37931207 DOI: 10.1182/blood.2023022222 |
0.212 |
|
| 2014 |
Schneider RK, Ademà V, Heckl D, Järås M, Mallo M, Lord AM, Chu LP, McConkey ME, Kramann R, Mullally A, Bejar R, Solé F, Ebert BL. Role of casein kinase 1A1 in the biology and targeted therapy of del(5q) MDS. Cancer Cell. 26: 509-20. PMID 25242043 DOI: 10.1016/J.Ccr.2014.08.001 |
0.211 |
|
| 2011 |
Eppert K, Takenaka K, Lechman ER, Waldron L, Nilsson B, van Galen P, Metzeler KH, Poeppl A, Ling V, Beyene J, Canty AJ, Danska JS, Bohlander SK, Buske C, Minden MD, ... ... Ebert BL, et al. Stem cell gene expression programs influence clinical outcome in human leukemia. Nature Medicine. 17: 1086-93. PMID 21873988 DOI: 10.1038/Nm.2415 |
0.211 |
|
| 2018 |
Ramakrishnan R, Peña-Martínez P, Agarwal P, Högberg C, Chapellier M, Shah M, Nilsson B, Ebert BL, Bhatia R, Järås M. CXCR4 Has a CXCL12-Independent Essential Role in MLL-AF9 Driven Acute Myeloid Leukemia Blood. 132: 774-774. DOI: 10.1182/blood-2018-99-116137 |
0.21 |
|
| 2011 |
Ebert B, Lipton JM. Diamond Blackfan anemia and ribosome biogenesis: introduction. Seminars in Hematology. 48: 73-4. PMID 21435502 DOI: 10.1053/J.Seminhematol.2011.01.003 |
0.209 |
|
| 2010 |
Lane SW, Sykes SM, Al-Shahrour F, Shterental S, Paktinat M, Lo Celso C, Jesneck JL, Ebert BL, Williams DA, Gilliland DG. The Apc(min) mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS. Blood. 115: 3489-97. PMID 20197553 DOI: 10.1182/Blood-2009-11-251728 |
0.209 |
|
| 2014 |
Raiser DM, Narla A, Ebert BL. The emerging importance of ribosomal dysfunction in the pathogenesis of hematologic disorders. Leukemia & Lymphoma. 55: 491-500. PMID 23863123 DOI: 10.3109/10428194.2013.812786 |
0.208 |
|
| 2011 |
Hartwell KA, Miller PG, Stewart AL, Kahn AR, Logan DJ, Negri J, Duvet M, Chattopadhyay S, Shterental S, Chu LP, Shieh JH, Jaeraas M, Dancik V, Narayan R, Huang C, ... ... Ebert BL, et al. Niche-Based Screening Reveals Leukemia Stem Cell Specific Therapeutics Blood. 118: 760-760. DOI: 10.1182/Blood.V118.21.760.760 |
0.208 |
|
| 2020 |
Miller P, Sperling AS, Gibson CJ, Viswanathan K, Castellano CA, McConkey ME, Ceremsak JJ, Taylor MS, Birndt S, Perner F, Arnason JE, Agrawal M, Schram A, Nikiforow S, Pihan G, ... ... Ebert BL, et al. Contribution of Clonal Hematopoiesis to Adult-Onset Hemophagocytic Lymphohistiocytosis. Blood. PMID 32961550 DOI: 10.1182/blood.2020008206 |
0.208 |
|
| 2010 |
Heinrichs S, Conover L, Bueso-Ramos CE, Kilpivaara O, Levine R, Stevenson K, Neuberg D, Bejar R, Ebert BL, Garcia-Manero G, Kantarjian HM, Look AT. MYBL2 Is a Candidate Tumor Suppressor Gene In MDS Blood. 116: 1865-1865. DOI: 10.1182/Blood.V116.21.1865.1865 |
0.207 |
|
| 2014 |
Fink EC, Krönke J, Hurst SN, Udeshi ND, Svinkina T, Schneider RK, McConkey ME, Järås M, Bullinger L, Carr SA, Ebert BL. Lenalidomide Induces Ubiquitination and Degradation of CSNK1A1 in MDS with Del(5q) Blood. 124: 4-4. DOI: 10.1182/Blood.V124.21.4.4 |
0.206 |
|
| 2019 |
Nazha A, Sekeres MA, Bejar R, Rauh MJ, Othus M, Komrokji RS, Barnard J, Hilton CB, Kerr CM, Steensma DP, DeZern A, Roboz G, Garcia-Manero G, Erba H, Ebert BL, et al. Genomic Biomarkers to Predict Resistance to Hypomethylating Agents in Patients With Myelodysplastic Syndromes Using Artificial Intelligence. Jco Precision Oncology. 3. PMID 31663066 DOI: 10.1200/po.19.00119 |
0.206 |
|
| 2014 |
Chen E, Ahn J, Breyfogle LJ, Green AR, Ebert BL, Mullally A. The Recql5 Helicase Is a Novel Downstream Target of Jak2V617F and Maintains Genome Stability in Response to Replication Stress Blood. 124: 822-822. DOI: 10.1182/blood.v124.21.822.822 |
0.205 |
|
| 2021 |
Miller PG, Sperling AS, Brea EJ, Leick MB, Fell GG, Jan M, Gohil SH, Tai YT, Munshi NC, Wu CJ, Neuberg DS, Maus MV, Jacobson C, Gibson CJ, Ebert BL. Clonal hematopoiesis in patients receiving chimeric antigen receptor T-cell therapy. Blood Advances. 5: 2982-2986. PMID 34342642 DOI: 10.1182/bloodadvances.2021004554 |
0.205 |
|
| 2013 |
Schneider RK, Heckl D, Järås M, Chu L, Marie M, Mullally A, Ebert BL. Critical Role Of Casein Kinase (Ck)1α Heterozygote Gene Inactivation In The Clonal Advantage Of Hematopoietic Stem Cells In Del(5q) MDS Blood. 122: 98-98. DOI: 10.1182/blood.v122.21.98.98 |
0.204 |
|
| 2022 |
Sellar RS, Sperling AS, Słabicki M, Gasser JA, McConkey ME, Donovan KA, Mageed N, Adams DN, Zou C, Miller PG, Dutta RK, Boettcher S, Lin AE, Sandoval BE, Quevedo Barrios VA, ... ... Ebert BL, et al. Degradation of GSPT1 causes TP53-independent cell death in leukemia whilst sparing normal hematopoietic stem cells. The Journal of Clinical Investigation. PMID 35763353 DOI: 10.1172/JCI153514 |
0.203 |
|
| 2010 |
Mullally A, Lane SW, Ball B, Megerdichian C, Okabe R, Al-Shahrour F, Paktinat M, Haydu JE, Housman E, Lord AM, Wernig G, Kharas MG, Mercher T, Kutok JL, Gilliland DG, ... Ebert BL, et al. Physiological Jak2V617F Expression Causes a Lethal Myeloproliferative Neoplasm with Differential Effects on Hematopoietic Stem and Progenitor Cells Cancer Cell. 17: 584-596. PMID 20541703 DOI: 10.1016/j.ccr.2010.05.015 |
0.203 |
|
| 2010 |
Narla A, Ebert BL. Ribosomopathies: human disorders of ribosome dysfunction. Blood. 115: 3196-205. PMID 20194897 DOI: 10.1182/blood-2009-10-178129 |
0.203 |
|
| 2013 |
Krönke J, Udeshi N, Narla A, Grauman P, Hurst S, McConkey M, Svinkina T, Heckl D, Comer E, Li X, Ciarlo C, Hartman E, Schenone M, Schreiber S, Carr SA, ... Ebert BL, et al. Lenalidomide Promotes CRBN-Mediated Ubiquitination and Degradation of IKZF1 and IKZF3 Blood. 122: LBA-5-LBA-5. DOI: 10.1182/Blood.V122.21.Lba-5.Lba-5 |
0.202 |
|
| 2010 |
Virgilio M, Payne E, Narla A, Sun H, Paw B, Look AT, Ebert BL, Berliner N, Khanna-Gupta A. Treatment of Zebrafish Models of Ribosomopathies (Diamond Blackfan Anemia (DBA) and 5q- Syndrome) with L-Leucine Results In An Improvement of Anemia and Developmental Defects: Evidence for a Common Pathway? Blood. 116: 195-195. DOI: 10.1182/Blood.V116.21.195.195 |
0.202 |
|
| 2019 |
Stalmann US, Ticconi F, Li R, Wong AB, Cowley G, Root DE, Heckl D, Snoeren I, Martinez S, Brümmendorf TH, Schuppert A, Costa I, Ebert BL, Schneider RK. Deconstructing the Clonal Advantage and Clonal Stability of 5q- Candidate Genes in Del(5q) MDS on a Single Cell Level Blood. 134: 559-559. DOI: 10.1182/Blood-2019-122588 |
0.202 |
|
| 2008 |
Ebert BL, Pretz J, Bosco J, Chang CY, Tamayo P, Galili N, Raza A, Root DE, Attar E, Ellis SR, Golub TR. Identification of RPS14 as a 5q- syndrome gene by RNA interference screen. Nature. 451: 335-9. PMID 18202658 DOI: 10.1038/Nature06494 |
0.201 |
|
| 2014 |
Schneider RK, McConkey ME, Chu LP, Ebert BL. Reduced Protein Synthesis and p53 Activation in Late-Stage Erythroblasts Mediate the Erythroid Differentiation Defect in Mice with Ribosomal Protein S14 Haploinsufficiency Blood. 124: 1892-1892. DOI: 10.1182/BLOOD.V124.21.1892.1892 |
0.2 |
|
| 2013 |
Hoestgaard-Jensen K, O'Connor RM, Dalby NO, Simonsen C, Finger BC, Golubeva A, Hammer H, Bergmann ML, Kristiansen U, Krogsgaard-Larsen P, Bräuner-Osborne H, Ebert B, Frølund B, Cryan JF, Jensen AA. The orthosteric GABAA receptor ligand Thio-4-PIOL displays distinctly different functional properties at synaptic and extrasynaptic receptors. British Journal of Pharmacology. 170: 919-32. PMID 23957253 DOI: 10.1111/Bph.12340 |
0.2 |
|
| 2015 |
Renneville A, Van Galen P, Canver MC, McConkey M, Krill-Burger JM, Dorfman DM, Holson EB, Bernstein BE, Orkin SH, Bauer DE, Ebert BL. EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression. Blood. 126: 1930-9. PMID 26320100 DOI: 10.1182/Blood-2015-06-649087 |
0.2 |
|
| 2020 |
Honigberg MC, Zekavat SM, Niroula A, Griffin GK, Bick AG, Pirruccello JP, Nakao T, Whitsel EA, Farland LV, Laurie C, Kooperberg C, Manson JE, Gabriel S, Libby P, Reiner AP, ... Ebert BL, et al. Premature Menopause, Clonal Hematopoiesis, and Coronary Artery Disease in Postmenopausal Women. Circulation. PMID 33161765 DOI: 10.1161/CIRCULATIONAHA.120.051775 |
0.199 |
|
| 2020 |
Miller PG, Niroula A, Ceremsak JJ, Gibson CJ, Taylor MS, Birndt S, Perner F, Arnason J, Sperling AS, Agrawal M, Schram AM, Nikiforow S, Pihan G, Hasserjian RP, Aster JC, ... ... Ebert BL, et al. Identification of germline variants in adults with hemophagocytic lymphohistiocytosis. Blood Advances. 4: 925-929. PMID 32150605 DOI: 10.1182/Bloodadvances.2019001272 |
0.199 |
|
| 2020 |
Bolton KL, Ptashkin RN, Gao T, Braunstein L, Devlin SM, Patel M, Berthon A, Syed A, Yabe M, Coombs C, Caltabellotta NM, Walsh M, Offit K, Stadler Z, Lee C, ... ... Ebert B, et al. Abstract 5703: Oncologic therapy shapes the fitness landscape of clonal hematopoiesis Tumor Biology. DOI: 10.1158/1538-7445.Am2020-5703 |
0.199 |
|
| 2009 |
Dutt S, Narla A, Kutok JL, Ebert BL. Lineage-Specific Activation of p53 in Response to Ribosomal Haploinsufficiency in Human Bone Marrow Cells. Blood. 114: 948-948. DOI: 10.1182/BLOOD.V114.22.948.948 |
0.199 |
|
| 2014 |
Järås M, Miller PG, Chu LP, Puram RV, Fink EC, Schneider RK, Al-Shahrour F, Peña P, Breyfogle LJ, Hartwell KA, McConkey ME, Cowley GS, Root DE, Kharas MG, Mullally A, ... Ebert BL, et al. Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia. The Journal of Experimental Medicine. 211: 605-12. PMID 24616378 DOI: 10.1084/Jem.20131033 |
0.198 |
|
| 2008 |
Zhang W, Ebert BL, Berkofsky-Fessler W, Buzzai M, Sun Y, Xi C, Levine RL, Gilliland DG, Licht JD. Integrative Analysis of Genomic Aberration and Gene Expression Suggests That MPD with Loss of Heterozygosity or Gain of Chromosome 9 Represents a Distinct Entity Blood. 112: 3735-3735. DOI: 10.1182/blood.v112.11.3735.3735 |
0.198 |
|
| 2013 |
Miller PG, Al-Shahrour F, Hartwell KA, Chu LP, Järås M, Puram RV, Puissant A, Callahan KP, Ashton J, McConkey ME, Poveromo LP, Cowley GS, Kharas MG, Labelle M, Shterental S, ... ... Ebert BL, et al. In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling. Cancer Cell. 24: 45-58. PMID 23770013 DOI: 10.1016/J.Ccr.2013.05.004 |
0.198 |
|
| 2020 |
Marion W, Boettcher S, Ruiz-Torres S, Lummertz da Rocha E, Lundin V, Morris V, Chou S, Zhao AM, Kubaczka C, Aumais O, Zhang Y, Shimamura A, Schlaeger TM, North TE, Ebert BL, et al. An induced pluripotent stem cell model of Fanconi anemia reveals mechanisms of p53-driven progenitor cell differentiation. Blood Advances. 4: 4679-4692. PMID 33002135 DOI: 10.1182/bloodadvances.2020001593 |
0.197 |
|
| 2024 |
Lin AE, Bapat AC, Xiao L, Niroula A, Ye J, Wong WJ, Agrawal M, Farady CJ, Boettcher A, Hergott CB, McConkey M, Flores-Bringas P, Shkolnik V, Bick AG, Milan D, ... ... Ebert BL, et al. Clonal Hematopoiesis of Indeterminate Potential With Loss of Enhances Risk for Atrial Fibrillation Through Inflammasome Activation. Circulation. PMID 38357791 DOI: 10.1161/CIRCULATIONAHA.123.065597 |
0.196 |
|
| 2011 |
Dutt S, Narla A, Lin K, Mullally A, Abayasekara N, Megerdichian C, Wilson FH, Currie T, Khanna-Gupta A, Berliner N, Kutok JL, Ebert BL. Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells. Blood. 117: 2567-76. PMID 21068437 DOI: 10.1182/Blood-2010-07-295238 |
0.196 |
|
| 2016 |
Zhu N, Chen M, Eng R, DeJong J, Sinha AU, Rahnamay NF, Koche R, Al-Shahrour F, Minehart JC, Chen CW, Deshpande AJ, Xu H, Chu SH, Ebert BL, Roeder RG, et al. MLL-AF9- and HOXA9-mediated acute myeloid leukemia stem cell self-renewal requires JMJD1C. The Journal of Clinical Investigation. PMID 26878175 DOI: 10.1172/Jci82978 |
0.195 |
|
| 1983 |
Renneberg R, Damerau W, Jung C, Ebert B, Scheller F. Study of H2O2-supported N-demethylations catalyzed by cytochrome P-450 and horseradish peroxidase Biochemical and Biophysical Research Communications. 113: 332-339. PMID 6305355 DOI: 10.1016/0006-291X(83)90470-9 |
0.195 |
|
| 2013 |
Wen QJ, Goldenson B, Malinge S, Stein BL, Lasho TL, Breyfogle L, Schultz R, Yang Q, gilles-Gendre L, Koppikar P, Abdel-Wahab O, Ebert BL, Pardanani A, Gurbuxani S, Levine RL, et al. Aurora A Kinase Is a Novel Therapeutic Target In The Myeloproliferative Neoplasms Blood. 122: 109-109. DOI: 10.1182/Blood.V122.21.109.109 |
0.195 |
|
| 2022 |
Bernard E, Tuechler H, Greenberg PL, Hasserjian RP, Arango Ossa JE, Nannya Y, Devlin SM, Creignou M, Pinel P, Monnier L, Gundem G, Medina-Martinez JS, Domenico D, Jädersten M, Germing U, ... ... Ebert BL, et al. Molecular International Prognostic Scoring System for Myelodysplastic Syndromes. Nejm Evidence. 1: EVIDoa2200008. PMID 38319256 DOI: 10.1056/EVIDoa2200008 |
0.194 |
|
| 2013 |
Shah D, Takahasi-Makise N, Narla A, Seguin A, Hattangadi S, Ebert B, Ward D, Campanella M, Dailey H, Kaplan J, Paw B. Declined presentation Experimental Hematology. 41: S25. DOI: 10.1016/J.Exphem.2013.05.100 |
0.193 |
|
| 2011 |
Kahn AR, Hartwell KA, Miller PG, Ebert BL, Golub TR, Moore MA. Selective Targeting of Leukemic Over Normal Stem Cells by the Serotonin Receptor Antagonist SB-216641 Blood. 118: 1884-1884. DOI: 10.1182/BLOOD.V118.21.1884.1884 |
0.193 |
|
| 2019 |
Jan M, Leventhal MJ, Morgan EA, Wengrod JC, Nag A, Drinan SD, Wollison BM, Ducar MD, Thorner AR, Leppanen S, Baronas J, Stevens J, Lane WJ, Kekre N, Ho VT, ... ... Ebert BL, et al. Recurrent genetic HLA loss in AML relapsed after matched unrelated allogeneic hematopoietic cell transplantation. Blood Advances. 3: 2199-2204. PMID 31324640 DOI: 10.1182/Bloodadvances.2019000445 |
0.192 |
|
| 2006 |
Galili N, Ebert BL, Westervelt P, Wasserman J, Lee D, Raza FZ, Golub TR, Raza A. Expression of Proliferation Related Genes in Myelodysplastic Syndromes (MDS) and Secondary Acute Myeloid Leukemia (AML) Patients with Resistance to Low Dose Vidaza and Thalidomide. Blood. 108: 2658-2658. DOI: 10.1182/blood.v108.11.2658.2658 |
0.192 |
|
| 2013 |
Bejar R, Stevenson K, Stojanov P, Zaneveld J, Bar-Natan M, Caughey B, Wang H, Garcia-Manero G, Kantarjian H, Cibulskis K, Getz G, Steensma D, Stone R, Chen R, Neuberg D, ... Ebert B, et al. O-024 Next-generation sequencing of 213 MDS patient samples identifies mutation profiles associated with response to hypomethylating agents and overall survival Leukemia Research. 37: S19-S20. DOI: 10.1016/S0145-2126(13)70046-8 |
0.192 |
|
| 2016 |
Macari ER, Taylor AM, Raiser D, Siva K, McGrath K, Humphries JM, Flygare J, Ebert BL, Zon LI. Calmodulin Inhibition Rescues DBA Models with Ribosomal Protein Deficiency through Reduction of RSK Signaling Blood. 128: 332-332. DOI: 10.1182/Blood.V128.22.332.332 |
0.191 |
|
| 2013 |
Khan S, Stewart AL, Mukherjee S, Scheiber SL, Ebert BL, Golub TR, Scadden DT, Moore MA. Ex Vivo expansion Of Umbilical Cord Blood CD34+ Cells Under Hypoxic Conditions Using Novel Compound#999 With Cytokines Blood. 122: 4508-4508. DOI: 10.1182/Blood.V122.21.4508.4508 |
0.191 |
|
| 2022 |
Fiskus W, Boettcher S, Daver N, Mill CP, Sasaki K, Birdwell CE, Davis JA, Takahashi K, Kadia TM, DiNardo CD, Jin Q, Qi Y, Su X, McGeehan GM, Khoury JD, ... Ebert BL, et al. Effective Menin inhibitor-based combinations against AML with MLL rearrangement or NPM1 mutation (NPM1c). Blood Cancer Journal. 12: 5. PMID 35017466 DOI: 10.1038/s41408-021-00603-3 |
0.191 |
|
| 2014 |
Shalem O, Sanjana NE, Hartenian E, Shi X, Scott DA, Mikkelsen TS, Heckl D, Ebert BL, Root DE, Doench JG, Zhang F. Genome-scale CRISPR-Cas9 knockout screening in human cells. Science (New York, N.Y.). 343: 84-7. PMID 24336571 DOI: 10.1126/Science.1247005 |
0.191 |
|
| 2023 |
Uddin MM, Saadatagah S, Niroula A, Yu B, Hornsby W, Ganesh S, Lannery K, Shuermans A, Honigberg MC, Bick AG, Libby P, Ebert BL, Ballantyne CM, Natarajan P. Long-term longitudinal analysis of 4,187 participants reveals new insights into determinants of incident clonal hematopoiesis. Medrxiv : the Preprint Server For Health Sciences. PMID 37732181 DOI: 10.1101/2023.09.05.23295093 |
0.19 |
|
| 2014 |
Eriksson M, Peña P, Chapellier M, Högberg C, Fioretos T, Ebert BL, Järås M. Toll-like Receptor 1 Is a Candidate Therapeutic Target in Acute Myeloid Leukemia Blood. 124: 5782-5782. DOI: 10.1182/BLOOD.V124.21.5782.5782 |
0.189 |
|
| 2013 |
Hartwell KA, Miller PG, Mukherjee S, Kahn AR, Stewart AL, Logan DJ, Negri JM, Duvet M, Järås M, Puram R, Dancik V, Al-Shahrour F, Kindler T, Tothova Z, Chattopadhyay S, ... ... Ebert BL, et al. Niche-based screening identifies small-molecule inhibitors of leukemia stem cells. Nature Chemical Biology. 9: 840-8. PMID 24161946 DOI: 10.1038/Nchembio.1367 |
0.189 |
|
| 2021 |
Zekavat SM, Lin SH, Bick AG, Liu A, Paruchuri K, Wang C, Uddin MM, Ye Y, Yu Z, Liu X, Kamatani Y, Bhattacharya R, Pirruccello JP, Pampana A, Loh PR, ... ... Ebert BL, et al. Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection. Nature Medicine. PMID 34099924 DOI: 10.1038/s41591-021-01371-0 |
0.188 |
|
| 2018 |
Bellutti F, Tigan AS, Nebenfuehr S, Dolezal M, Zojer M, Grausenburger R, Hartenberger S, Kollmann S, Doma E, Prchal-Murphy M, Uras IZ, Höllein A, Neuberg DS, Ebert BL, Ringler A, et al. CDK6 Antagonizes p53-Induced Responses during Tumorigenesis. Cancer Discovery. PMID 29899063 DOI: 10.1158/2159-8290.Cd-17-0912 |
0.188 |
|
| 2022 |
Stalmann USA, Ticconi F, Snoeren IAM, Li R, Gleitz H, Cowley G, McConkey ME, Wong AB, Schmitz S, Fuchs SNR, Sood S, Leimkühler NB, Martinez-Høyer S, Banjanin B, Root DE, ... ... Ebert BL, et al. Genetic barcoding systematically comparing genes in del(5q) MDS reveals a central role for CSNK1A1 in clonal expansion. Blood Advances. PMID 35016204 DOI: 10.1182/bloodadvances.2021006061 |
0.188 |
|
| 2007 |
Ebert BL, Pretz J, Bosco J, Chang CY, Tamayo P, Galili N, Raza A, Root D, Attar E, Ellis SR, Golub TR. Identification of RPS14 as the 5q-Syndrome Gene by RNA Interference Screen. Blood. 110: 1-1. DOI: 10.1182/Blood.V110.11.1.1 |
0.187 |
|
| 2012 |
Taylor AM, Raiser DM, Humphries JM, Ebert BL, Zon LI. Calmodulin Inhibition Rescues the Effects of Ribosomal Protein Deficiency by Modulating p53 Activity in Models of Diamond Blackfan Anemia Blood. 120: 512-512. DOI: 10.1182/Blood.V120.21.512.512 |
0.187 |
|
| 2019 |
Sperling AS, Leventhal M, Gibson CJ, Ebert BL, Steensma DP. Myelodysplastic syndromes (MDS) occurring in Agent Orange exposed individuals carry a mutational spectrum similar to that of MDS. Leukemia & Lymphoma. 1-4. PMID 31714164 DOI: 10.1080/10428194.2019.1689394 |
0.186 |
|
| 2011 |
Narla A, Dutt S, McAuley JR, Al-Shahrour F, Hurst S, McConkey M, Neuberg D, Ebert BL. Dexamethasone and lenalidomide have distinct functional effects on erythropoiesis. Blood. 118: 2296-304. PMID 21527522 DOI: 10.1182/blood-2010-11-318543 |
0.185 |
|
| 2013 |
Lindsley RC, Ebert BL. The biology and clinical impact of genetic lesions in myeloid malignancies. Blood. 122: 3741-8. PMID 23954890 DOI: 10.1182/blood-2013-06-460295 |
0.185 |
|
| 2013 |
Mullally A, Ebert BL. Sinister symbiosis: pathological hematopoietic-stromal interactions in CML. Cell Stem Cell. 13: 257-8. PMID 24012363 DOI: 10.1016/j.stem.2013.08.009 |
0.183 |
|
| 2008 |
Sohal DP, Pellagati A, Zhou L, Mo Y, Opalinska JB, Alencar C, Heuck C, Wickrema A, Friedman E, Greally J, Ebert BL, Warner J, Boultwood J, Verma A. Downregulation of Ribosomal Proteins Is Seen in Non 5q- MDS Blood. 112: 854-854. DOI: 10.1182/Blood.V112.11.854.854 |
0.183 |
|
| 2010 |
Mullally A, Ebert BL. STATistical power of clonal analysis: differential STAT1 pathway activation downstream of the JAK2V617F mutation. Cancer Cell. 18: 405-6. PMID 21075304 DOI: 10.1016/j.ccr.2010.10.037 |
0.183 |
|
| 2022 |
Sella T, Fell GG, Miller PG, Gibson CJ, Rosenberg SM, Snow C, Stover DG, Ruddy KJ, Peppercorn JM, Schapira L, Borges VF, Come SE, Warner E, Frank E, Neuberg D, ... Ebert BL, et al. Patient perspectives on testing for clonal hematopoiesis of indeterminate potential. Blood Advances. PMID 36129839 DOI: 10.1182/bloodadvances.2022008376 |
0.182 |
|
| 2019 |
Khadka P, Reitman ZJ, Buchan G, Hartley R, Bear H, Georgis Y, Jarmale S, Schoolcraft K, Miller P, Stiles CD, Chowdhury D, Haas-Kogan D, Johannessen C, Ebert BL, Ligon KL, et al. DIPG-12. CHARACTERIZING THE ROLE OF PPM1D MUTATIONS IN THE PATHOGENESIS OF DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPGs) Neuro-Oncology. 21: ii70-ii71. DOI: 10.1093/Neuonc/Noz036.033 |
0.181 |
|
| 2022 |
Schimmer R, Kovtonyuk LV, Klemm N, Fullin J, Stolz SM, Mueller J, Francisco C, Kurppa KJ, Ebert BL, Manz MG, Boettcher S. TP53 mutations confer resistance to hypomethylating agents and BCL-2 inhibition in myeloid neoplasms. Blood Advances. PMID 35026842 DOI: 10.1182/bloodadvances.2021005859 |
0.181 |
|
| 2024 |
Bhattacharya R, Uddin MM, Patel AP, Niroula A, Finneran P, Bernardo R, Fitch KV, Lu MT, Bloomfield GS, Malvestutto C, Aberg JA, Fichtenbaum CJ, Hornsby W, Ribaudo H, Libby P, ... Ebert BL, et al. Risk Factors for Clonal Hematopoiesis of Indeterminate Potential in People with HIV: a report from the REPRIEVE Trial. Blood Advances. PMID 38197863 DOI: 10.1182/bloodadvances.2023011324 |
0.181 |
|
| 2011 |
Yusuf RZ, Acharya SS, Yu V, Saez B, Duvet M, Scadden E, Warraich G, Clish C, Churchill M, Doench J, Logan DJ, Cook C, Das S, Brown A, Sykes SM, ... ... Ebert BL, et al. Distinct Metabolic Dependency of Normal and Leukemic Cells in a Mouse Model Blood. 118: 759-759. DOI: 10.1182/Blood.V118.21.759.759 |
0.18 |
|
| 2008 |
Karliova M, Ebert B, Berger J, Macdonald R, Dietel M, Ortner M, Lochs H, Voderholzer W. Fluoreszenzendoskopie bei Patienten mit Barrett Ösophagus: Bildüberlagerungstechnik als diagnostische Innovation Zeitschrift Fur Gastroenterologie. 46: 428. DOI: 10.1055/S-0028-1089803 |
0.178 |
|
| 2006 |
Pikman Y, Lee BH, Mercher T, McDowell E, Ebert BL, Gozo M, Cuker A, Wernig G, Moore S, Galinsky I, DeAngelo DJ, Clark JJ, Lee SJ, Golub TR, Wadleigh M, et al. MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia. Plos Medicine. 3: e270. PMID 16834459 DOI: 10.1371/journal.pmed.0030270 |
0.178 |
|
| 2011 |
Rice KL, Lin X, Wolniak K, Ebert BL, Berkofsky-Fessler W, Buzzai M, Sun Y, Xi C, Elkin P, Levine R, Golub T, Gilliland DG, Crispino JD, Licht JD, Zhang W. Analysis of genomic aberrations and gene expression profiling identifies novel lesions and pathways in myeloproliferative neoplasms. Blood Cancer Journal. 1: e40. PMID 22829077 DOI: 10.1038/Bcj.2011.39 |
0.178 |
|
| 2011 |
Nelson EA, Walker SR, Weisberg E, Bar-Natan M, Barrett R, Gashin LB, Terrell S, Klitgaard JL, Santo L, Addorio MR, Ebert BL, Griffin JD, Frank DA. The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors. Blood. 117: 3421-9. PMID 21233313 DOI: 10.1182/Blood-2009-11-255232 |
0.177 |
|
| 2010 |
Zimmer M, Lamb J, Ebert BL, Lynch M, Neil C, Schmidt E, Golub TR, Iliopoulos O. The connectivity map links iron regulatory protein-1-mediated inhibition of hypoxia-inducible factor-2a translation to the anti-inflammatory 15-deoxy-delta12,14-prostaglandin J2. Cancer Research. 70: 3071-9. PMID 20354189 DOI: 10.1158/0008-5472.CAN-09-2877 |
0.177 |
|
| 2011 |
Novershtern N, Subramanian A, Lawton LN, Mak RH, Haining WN, McConkey ME, Habib N, Yosef N, Chang CY, Shay T, Frampton GM, Drake AC, Leskov I, Nilsson B, Preffer F, ... ... Ebert BL, et al. Densely interconnected transcriptional circuits control cell states in human hematopoiesis. Cell. 144: 296-309. PMID 21241896 DOI: 10.1016/J.Cell.2011.01.004 |
0.177 |
|
| 2015 |
Rebekka SK, Schenone M, Ferreira Ventura M, Beier F, Bruemmendorf TH, Germing U, Platzbecker U, Büsche G, McConkey ME, Waters CS, Lindsley RC, Ebert BL. Cooperating Effect of Rps14, Csnk1a1 and miRNA145/miRNA146a Haploinsufficiency in the Activation of the Innate Immune System in Del(5q) MDS Blood. 126: 356-356. DOI: 10.1182/blood.V126.23.356.356 |
0.177 |
|
| 2017 |
Schneider RK, Mullally A, Dugourd A, Peisker F, Hoogenboezem R, Van Strien PMH, Bindels EM, Heckl D, Büsche G, Fleck D, Müller-Newen G, Wongboonsin J, Ventura Ferreira M, Puelles VG, Saez-Rodriguez J, ... Ebert BL, et al. Gli1(+) Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target. Cell Stem Cell. PMID 28457748 DOI: 10.1016/J.Stem.2017.03.008 |
0.177 |
|
| 2006 |
Thomas A, Kümmel S, Ebert B, Fischer T. Verbesserte Differenzierung von 300 Brustläsionen durch die Realtime-Elastographie Geburtshilfe Und Frauenheilkunde. 66. DOI: 10.1055/S-2006-952848 |
0.176 |
|
| 2016 |
Schneider RK, Schenone M, Ferreira MV, Kramann R, Joyce CE, Hartigan C, Beier F, Brümmendorf TH, Germing U, Platzbecker U, Büsche G, Knüchel R, Chen MC, Waters CS, Chen E, ... ... Ebert BL, et al. Rps14 haploinsufficiency causes a block in erythroid differentiation mediated by S100A8 and S100A9. Nature Medicine. PMID 26878232 DOI: 10.1038/Nm.4047 |
0.176 |
|
| 2012 |
Kahn AR, Hartwell KA, Miller PG, Ebert BL, Golub TR, Moore MAA. Identification of Small Molecules Selectively Targeting Leukemic Stem Cells within Their Stromal Niche Blood. 120: 413-413. DOI: 10.1182/BLOOD.V120.21.413.413 |
0.174 |
|
| 2019 |
Bernard E, Nannya Y, Yoshizato T, Hasserjian RP, Saiki R, Shiozawa Y, Devlin SM, Tuechler H, Sarian A, Malcovati L, Sole F, Haase D, Creignou M, Levine M, Germing U, ... ... Ebert BL, et al. TP53 State Dictates Genome Stability, Clinical Presentation and Outcomes in Myelodysplastic Syndromes Blood. 134: 675-675. DOI: 10.1182/Blood-2019-129392 |
0.173 |
|
| 2015 |
Kowalczyk MS, Tirosh I, Heckl D, Rao TN, Dixit A, Haas BJ, Schneider RK, Wagers AJ, Ebert BL, Regev A. Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells. Genome Research. PMID 26430063 DOI: 10.1101/Gr.192237.115 |
0.173 |
|
| 2023 |
Nishida Y, Ishizawa J, Ayoub E, Montoya RH, Ostermann LB, Muftuoglu M, Ruvolo VR, Patsilevas T, Scruggs DA, Khazaei S, Mak PY, Tao W, Carter BZ, Boettcher S, Ebert BL, et al. Enhanced reactivation disrupts transcriptional program and overcomes venetoclax resistance in acute myeloid leukemias. Science Advances. 9: eadh1436. PMID 38019903 DOI: 10.1126/sciadv.adh1436 |
0.173 |
|
| 2020 |
Boettcher S, Wilk CM, Singer J, Beier F, Burcklen E, Beisel C, Ventura Ferreira MS, Gourri E, Gassner C, Frey BM, Schanz U, Skoda RC, Ebert BL, Brümmendorf TH, Beerenwinkel N, et al. Clonal hematopoiesis in donors and long-term survivors of related allogeneic hematopoietic stem cell transplantation. Blood. PMID 32181816 DOI: 10.1182/Blood.2019003079 |
0.172 |
|
| 2004 |
Ebert BL, Golub TR. Genomic approaches to hematologic malignancies. Blood. 104: 923-32. PMID 15155462 DOI: 10.1182/blood-2004-01-0274 |
0.17 |
|
| 2016 |
Bhola PD, Mar BG, Lindsley RC, Ryan JA, Hogdal LJ, Vo TT, DeAngelo DJ, Galinsky I, Ebert BL, Letai A. Functionally identifiable apoptosis-insensitive subpopulations determine chemoresistance in acute myeloid leukemia. The Journal of Clinical Investigation. PMID 27599292 DOI: 10.1172/Jci82908 |
0.169 |
|
| 2012 |
Koppikar P, Bhagwat N, Kilpivaara O, Manshouri T, Adli M, Hricik T, Liu F, Saunders LM, Mullally A, Abdel-Wahab O, Leung L, Weinstein A, Marubayashi S, Goel A, Gönen M, ... ... Ebert BL, et al. Heterodimeric JAK-STAT activation as a mechanism of persistence to JAK2 inhibitor therapy. Nature. 489: 155-9. PMID 22820254 DOI: 10.1038/Nature11303 |
0.169 |
|
| 2024 |
Mueller J, Schimmer RR, Koch C, Schneiter F, Fullin J, Lysenko V, Pellegrino C, Klemm N, Russkamp N, Myburgh R, Volta L, Theocharides AP, Kurppa KJ, Ebert BL, Schroeder T, et al. Targeting the mevalonate or Wnt pathways to overcome CAR T-cell resistance in TP53-mutant AML cells. Embo Molecular Medicine. PMID 38355749 DOI: 10.1038/s44321-024-00024-2 |
0.169 |
|
| 2010 |
Bradner JE, Mak R, Tanguturi SK, Mazitschek R, Haggarty SJ, Ross K, Chang CY, Bosco J, West N, Morse E, Lin K, Shen JP, Kwiatkowski NP, Gheldof N, Dekker J, ... ... Ebert BL, et al. Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease. Proceedings of the National Academy of Sciences of the United States of America. 107: 12617-22. PMID 20616024 DOI: 10.1073/Pnas.1006774107 |
0.168 |
|
| 2015 |
Kramann R, Schneider RK, DiRocco DP, Machado F, Fleig S, Bondzie PA, Henderson JM, Ebert BL, Humphreys BD. Perivascular Gli1+ progenitors are key contributors to injury-induced organ fibrosis. Cell Stem Cell. 16: 51-66. PMID 25465115 DOI: 10.1016/j.stem.2014.11.004 |
0.168 |
|
| 2009 |
Ebert BL. Deletion 5q in myelodysplastic syndrome: a paradigm for the study of hemizygous deletions in cancer. Leukemia. 23: 1252-6. PMID 19322210 DOI: 10.1038/leu.2009.53 |
0.167 |
|
| 2017 |
Eriksson M, Peña-Martínez P, Ramakrishnan R, Chapellier M, Högberg C, Glowacki G, Orsmark-Pietras C, Velasco-Hernández T, Lazarević VL, Juliusson G, Cammenga J, Mulloy JC, Richter J, Fioretos T, Ebert BL, et al. Agonistic targeting of TLR1/TLR2 induces p38 MAPK-dependent apoptosis and NFκB-dependent differentiation of AML cells. Blood Advances. 1: 2046-2057. PMID 29296851 DOI: 10.1182/Bloodadvances.2017006148 |
0.167 |
|
| 2024 |
Yan C, Richard MA, Gibson CJ, He J, Bosworth A, Crossman DK, Singh P, Hageman L, Kalra R, Armenian SH, Vose J, Weisdorf DJ, Ebert BL, Yasui Y, Forman SJ, et al. Clonal Hematopoiesis and Therapy-Related Myeloid Neoplasms After Autologous Transplant for Hodgkin Lymphoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2302547. PMID 38635938 DOI: 10.1200/JCO.23.02547 |
0.166 |
|
| 2018 |
Ebert BL, Libby P. Clonal Hematopoiesis Confers Predisposition to Both Cardiovascular Disease and Cancer: A Newly Recognized Link Between Two Major Killers. Annals of Internal Medicine. 169: 116-117. PMID 29809241 DOI: 10.7326/M18-0737 |
0.166 |
|
| 2022 |
Döhner H, Wei AH, Appelbaum FR, Craddock C, DiNardo CD, Dombret H, Ebert BL, Fenaux P, Godley LA, Hasserjian RP, Larson RA, Levine RL, Miyazaki Y, Niederwieser D, Ossenkoppele GJ, et al. Diagnosis and Management of AML in Adults: 2022 ELN Recommendations from an International Expert Panel. Blood. PMID 35797463 DOI: 10.1182/blood.2022016867 |
0.165 |
|
| 2011 |
Virgilio M, Payne E, Narla A, Sun H, Paw BH, Look T, Ebert BL, Berliner N, Khanna-Gupta A. L-Leucine Improves the Anemia of the 5q- Syndrome Via Activation of the mTOR (mammalian target of rapamycin) Pathway Blood. 118: 970-970. DOI: 10.1182/Blood.V118.21.970.970 |
0.165 |
|
| 2013 |
Park S, Deering RP, Lu Y, Patrick T, Shenoy V, Lianoglou S, Al-Shahrour F, Leslie C, Ebert BL, Lengner C, Daley GQ, Kharas MG. Msi2 Directly Regulates The TGF-β Signaling Pathway and Myeloid Lineage Bias In Hematopoietic Stem Cells Blood. 122: 468-468. DOI: 10.1182/Blood.V122.21.468.468 |
0.165 |
|
| 2019 |
Jan M, Castano A, Walker A, Guirguis AA, Gasser JA, Bouffard AA, Slabicki M, Tepper A, Grinshpun DE, Kyung T, Sievers Q, Birnbaum ME, Maus MV, Ebert BL. Exploiting the Zinc Finger Degrome Targeted By Lenalidomide to Engineer Reversible Off-Switch Degradable Chimeric Antigen Receptors Blood. 134: 866-866. DOI: 10.1182/Blood-2019-124210 |
0.164 |
|
| 2010 |
Beroukhim R, Mermel CH, Porter D, Wei G, Raychaudhuri S, Donovan J, Barretina J, Boehm JS, Dobson J, Urashima M, Mc Henry KT, Pinchback RM, Ligon AH, Cho YJ, Haery L, ... ... Ebert BL, et al. The landscape of somatic copy-number alteration across human cancers. Nature. 463: 899-905. PMID 20164920 DOI: 10.1038/Nature08822 |
0.164 |
|
| 2022 |
Buesche G, Teoman H, Schneider RK, Ribezzo F, Ebert BL, Giagounidis A, Göhring G, Schlegelberger B, Bock O, Ganser A, Aul C, Germing U, Kreipe H. Evolution of severe (transfusion-dependent) anaemia in myelodysplastic syndromes with 5q deletion is characterized by a macrophage-associated failure of the eythropoietic niche. British Journal of Haematology. PMID 35362549 DOI: 10.1111/bjh.18163 |
0.164 |
|
| 2022 |
Fiskus W, Daver N, Boettcher S, Mill CP, Sasaki K, Birdwell CE, Davis JA, Das K, Takahashi K, Kadia TM, DiNardo CD, Burrows F, Loghavi S, Khoury JD, Ebert BL, et al. Activity of menin inhibitor ziftomenib (KO-539) as monotherapy or in combinations against AML cells with MLL1 rearrangement or mutant NPM1. Leukemia. PMID 36151141 DOI: 10.1038/s41375-022-01707-w |
0.164 |
|
| 2014 |
Krönke J, Udeshi ND, Narla A, Grauman P, Hurst SN, McConkey M, Svinkina T, Heckl D, Comer E, Li X, Ciarlo C, Hartman E, Munshi N, Schenone M, Schreiber SL, ... ... Ebert BL, et al. Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells. Science (New York, N.Y.). 343: 301-5. PMID 24292625 DOI: 10.1126/Science.1244851 |
0.163 |
|
| 2010 |
Ebert BL. Genetic deletions in AML and MDS. Best Practice & Research. Clinical Haematology. 23: 457-61. PMID 21130407 DOI: 10.1016/j.beha.2010.09.006 |
0.162 |
|
| 2019 |
Shirasaki R, de Matos Simoes R, Downey-Kopyscinski S, Matthews G, Hu Y, Sheffer M, Dhimolea E, Dashevsky O, Gandolfi S, Hengeveld P, Dempster J, Meyers R, Bryan J, Dharia N, McFarland J, ... ... Ebert B, et al. CRISPR studies identify genes preferentially essential for myeloma cells vs. other neoplasias: implications for future therapies selective against MM Clinical Lymphoma Myeloma and Leukemia. 19: e48-e49. DOI: 10.1016/J.Clml.2019.09.073 |
0.162 |
|
| 2018 |
Jan M, Leventhal MJ, Morgan EA, Wengrod JC, Nag A, Drinan SD, Wollison BM, Ducar MD, Thorner AR, Kekre N, Ho VT, Koreth J, Cutler CS, Nikiforow S, Alyea EP, ... ... Ebert BL, et al. Recurrent Genetic HLA Loss in Acute Myeloid Leukemia Relapsed after Matched Unrelated Allogeneic Hematopoietic Cell Transplant Blood. 132: 817-817. DOI: 10.1182/Blood-2018-99-113911 |
0.162 |
|
| 2012 |
Mullally A, Lane SW, Brumme K, Ebert BL. Myeloproliferative neoplasm animal models. Hematology/Oncology Clinics of North America. 26: 1065-81. PMID 23009938 DOI: 10.1016/j.hoc.2012.07.007 |
0.162 |
|
| 2018 |
Donovan KA, An J, Nowak RP, Yuan JC, Fink EC, Berry BC, Ebert BL, Fischer ES. Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray Syndrome. Elife. 7. PMID 30067223 DOI: 10.7554/eLife.38430 |
0.161 |
|
| 2011 |
Xu J, Peng C, Sankaran VG, Shao Z, Esrick EB, Chong BG, Ippolito GC, Fujiwara Y, Ebert BL, Tucker PW, Orkin SH. Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing. Science (New York, N.Y.). 334: 993-6. PMID 21998251 DOI: 10.1126/Science.1211053 |
0.16 |
|
| 2012 |
Lee J, Li M, Milwid J, Dunham J, Vinegoni C, Gorbatov R, Iwamoto Y, Wang F, Shen K, Hatfield K, Enger M, Shafiee S, McCormack E, Ebert BL, Weissleder R, et al. Implantable microenvironments to attract hematopoietic stem/cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 19638-43. PMID 23150542 DOI: 10.1073/Pnas.1208384109 |
0.16 |
|
| 2014 |
Park SM, Deering RP, Lu Y, Tivnan P, Lianoglou S, Al-Shahrour F, Ebert BL, Hacohen N, Leslie C, Daley GQ, Lengner CJ, Kharas MG. Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs. The Journal of Experimental Medicine. 211: 71-87. PMID 24395885 DOI: 10.1084/Jem.20130736 |
0.159 |
|
| 2009 |
Narla A, Dutt S, McAuley JR, Ebert BL. Lenalidomide and Dexamethasone Promote Erythropoiesis in Both Normal and RPS14 and RPS19 shRNA Infected Human CD34+ Cells: Implications for Therapy of Myelodysplastic Syndrome and Diamond-Blackfan Anemia. Blood. 114: 1092-1092. DOI: 10.1182/blood.v114.22.1092.1092 |
0.159 |
|
| 2016 |
Döhner H, Estey E, Grimwade D, Amadori S, Appelbaum FR, Büchner T, Dombret H, Ebert BL, Fenaux P, Larson RA, Levine RL, Lo-Coco F, Naoe T, Niederwieser D, Ossenkoppele GJ, et al. Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel. Blood. PMID 27895058 DOI: 10.1182/blood-2016-08-733196 |
0.159 |
|
| 2018 |
Fink EC, McConkey M, Adams DN, Haldar SD, Kennedy JA, Guirguis AA, Udeshi ND, Mani DR, Chen M, Liddicoat B, Svinkina T, Nguyen AT, Carr SA, Ebert BL. Crbn is sufficient to confer sensitivity to thalidomide and its derivatives in mice. Blood. PMID 30064974 DOI: 10.1182/Blood-2018-05-852798 |
0.158 |
|
| 2012 |
Abayasekara N, Narla A, Hurst S, Sun H, Virgilio M, Payne E, Ebert BL, Look AT, Berliner N, Khanna-Gupta A. L-Leucine Improves the Anemia of DBA and the 5q- Syndrome Via Activation of the mTOR Pathway in a p53-Independent Manner Blood. 120: 1257-1257. DOI: 10.1182/Blood.V120.21.1257.1257 |
0.158 |
|
| 2021 |
Yu B, Roberts MB, Raffield LM, Zekavat SM, Nguyen NQH, Biggs ML, Brown MR, Griffin G, Desai P, Correa A, Morrison AC, Shah AM, Niroula A, Uddin MM, Honigberg MC, ... Ebert BL, et al. Supplemental Association of Clonal Hematopoiesis With Incident Heart Failure. Journal of the American College of Cardiology. 78: 42-52. PMID 34210413 DOI: 10.1016/j.jacc.2021.04.085 |
0.157 |
|
| 2014 |
Mallo M, Tuechler H, Shih L, Ogawa S, Sanada M, Lin T, Ganster C, Shirneshan K, Haase D, López-Pavia M, Cervera J, Such E, Arenillas L, Garcia O, Adema V, ... ... Ebert BL, et al. Genomic Microarray Alterations Add Prognostic Power to the IPSS-R in MDS with Normal Karyotype Blood. 124: 3262-3262. DOI: 10.1182/blood.v124.21.3262.3262 |
0.157 |
|
| 2018 |
Shirasaki R, Gandolfi S, De Matos Simoes R, Matthews G, Buckley D, Dashevsky O, Downey-Kopyscinski SL, Tang H, Sheffer M, Dhimolea E, Glassner B, Bariteau M, Sorrell J, Bruggenthies JB, Sievers Q, ... ... Ebert BL, et al. CRISPR-Based Functional Genomics Studies Reveal Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins: Implications for Novel Therapeutics across Diverse Neoplasias Blood. 132: 1367-1367. DOI: 10.1182/Blood-2018-99-116232 |
0.157 |
|
| 2014 |
Doench JG, Hartenian E, Graham DB, Tothova Z, Hegde M, Smith I, Sullender M, Ebert BL, Xavier RJ, Root DE. Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation. Nature Biotechnology. 32: 1262-7. PMID 25184501 DOI: 10.1038/Nbt.3026 |
0.157 |
|
| 2017 |
Valent P, Orazi A, Steensma DP, Ebert BL, Haase D, Malcovati L, van de Loosdrecht AA, Haferlach T, Westers TM, Wells DA, Giagounidis A, Loken M, Orfao A, Lübbert M, Ganser A, et al. Proposed minimal diagnostic criteria for myelodysplastic syndromes (MDS) and potential pre-MDS conditions. Oncotarget. 8: 73483-73500. PMID 29088721 DOI: 10.18632/oncotarget.19008 |
0.157 |
|
| 2015 |
Fink EC, Ebert BL. The novel mechanism of lenalidomide activity. Blood. 126: 2366-9. PMID 26438514 DOI: 10.1182/blood-2015-07-567958 |
0.157 |
|
| 2006 |
Ebert BL, Galili N, Tamayo P, Mak R, Pretz J, Ladd-Acosta C, Stone R, Golub TR, Raza A. An Erythroid Differentiation Gene Expression Signature Predicts Response to Lenalidomide in Myelodysplasia. Blood. 108: 2668-2668. DOI: 10.1182/Blood.V108.11.2668.2668 |
0.156 |
|
| 2019 |
Lesch BJ, Tothova Z, Morgan EA, Liao Z, Bronson RT, Ebert BL, Page DC. Intergenerational epigenetic inheritance of cancer susceptibility in mammals. Elife. 8. PMID 30963999 DOI: 10.7554/Elife.39380 |
0.155 |
|
| 2017 |
Lucas D, O'Leary HA, Ebert BL, Cowan CA, Tremblay CS. Utility of CRISPR/Cas9 systems in hematology research. Experimental Hematology. PMID 28668351 DOI: 10.1016/J.Exphem.2017.06.006 |
0.154 |
|
| 2015 |
Esrick EB, McConkey M, Lin K, Frisbee A, Ebert BL. Inactivation of HDAC1 or HDAC2 induces gamma globin expression without altering cell cycle or proliferation. American Journal of Hematology. 90: 624-8. PMID 25808664 DOI: 10.1002/ajh.24019 |
0.154 |
|
| 2021 |
Zoref-Lorenz A, Murakami J, Hofstetter L, Iyer SP, Alotaibi AS, Mohamed SF, Miller PG, Guber E, Weinstein S, Yacobovich J, Nikiforow S, Ebert BL, Lane A, Pasvolsky O, Raanani P, et al. An improved index for diagnosis and mortality prediction in malignancy associated hemophagocytic lymphohistiocytosis. Blood. PMID 34780598 DOI: 10.1182/blood.2021012764 |
0.154 |
|
| 2012 |
Raiser DM, Ebert BL. Overexpression of Ribosomal Proteins Is Insufficient for p53 Pathway Induction in Cell Lines and Primary CD34+ Cells Blood. 120: 3479-3479. DOI: 10.1182/blood.v120.21.3479.3479 |
0.154 |
|
| 2006 |
Kim WY, Safran M, Buckley MRM, Ebert BL, Glickman J, Bosenberg M, Regan M, Kaelin WG. Failure to prolyl hydroxylate hypoxia-inducible factor α phenocopies VHL inactivation in vivo Embo Journal. 25: 4650-4662. PMID 16977322 DOI: 10.1038/Sj.Emboj.7601300 |
0.153 |
|
| 2023 |
Mouhieddine TH, Nzerem C, Redd R, Dunford A, Leventhal M, Sklavenitis-Pistofidis R, Tahri S, El-Khoury H, Steensma DP, Ebert BL, Soiffer RJ, Keats JJ, Mehr S, Auclair D, Ghobrial IM, et al. Clinical outcomes and evolution of clonal hematopoiesis in patients with newly diagnosed multiple myeloma. Cancer Research Communications. PMID 38019104 DOI: 10.1158/2767-9764.CRC-23-0093 |
0.153 |
|
| 2012 |
Krönke J, Narla A, Hurst SN, Udeshi N, Schenone M, McConkey M, Grauman P, Heckl D, McAuley R, Ciarlo C, Comer E, Li X, Carr SA, Ebert BL. Inhibition of the CRBN-DDB1-CUL4-ROC1 E3 Ubiquitin Ligase Mediates the Anti-Proliferative and Immunomodulatory Properties of Lenalidomide Blood. 120: 919-919. DOI: 10.1182/Blood.V120.21.919.919 |
0.152 |
|
| 2012 |
Ebert BL. Discovery Science and Integrating Molecular Diagnosis into Clinical Practice Blood. 120: SCI-31-SCI-31. DOI: 10.1182/blood.v120.21.sci-31.sci-31 |
0.152 |
|
| 2022 |
Castillo D, Yuan TA, Nehoray B, Cervantes A, Tsang KK, Yang K, Sand SR, Mokhnatkin J, Herzog J, Slavin TP, Hyman S, Schwartz A, Ebert BL, Amos CI, Garber JE, et al. Clonal hematopoiesis and mosaicism revealed by a multi-tissue analysis of constitutional TP53 Status. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 35654360 DOI: 10.1158/1055-9965.EPI-21-1296 |
0.152 |
|
| 2013 |
Losman JA, Looper RE, Koivunen P, Lee S, Schneider RK, McMahon C, Cowley GS, Root DE, Ebert BL, Kaelin WG. (R)-2-hydroxyglutarate is sufficient to promote leukemogenesis and its effects are reversible. Science (New York, N.Y.). 339: 1621-5. PMID 23393090 DOI: 10.1126/Science.1231677 |
0.152 |
|
| 2012 |
Gansner JM, Rosas IO, Ebert BL. Pulmonary fibrosis, bone marrow failure, and telomerase mutation. The New England Journal of Medicine. 366: 1551-3. PMID 22512499 DOI: 10.1056/NEJMc1200999 |
0.152 |
|
| 2012 |
Okam MM, Ebert BL. Novel approaches to the treatment of sickle cell disease: the potential of histone deacetylase inhibitors. Expert Review of Hematology. 5: 303-11. PMID 22780210 DOI: 10.1586/ehm.12.20 |
0.151 |
|
| 2016 |
Nazha A, Sekeres MA, Bejar R, Barnard J, Al-Issa K, Przychodzen BP, Kalaycio M, Clemente MJ, Hirsch CM, Ebert BL, Maciejewski JP. Using Machine Intelligence Algorithms to Develop a Geno-Clinical Model to Predict Responses to Hypomethylating Agents in Myelodysplastic Syndromes Blood. 128: 3193-3193. DOI: 10.1182/Blood.V128.22.3193.3193 |
0.151 |
|
| 2020 |
Kurppa KJ, Liu Y, To C, Zhang T, Fan M, Vajdi A, Knelson EH, Xie Y, Lim K, Cejas P, Portell A, Lizotte PH, Ficarro SB, Li S, Chen T, ... ... Ebert BL, et al. Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway. Cancer Cell. 37: 104-122.e12. PMID 31935369 DOI: 10.1016/J.Ccell.2019.12.006 |
0.15 |
|
| 2012 |
Ramos P, Casu C, Gardenghi S, Breda L, Crielaard BJ, Gupta R, Guy E, Mariongiu MF, Levine RL, Abdel-Wahab O, Ebert BL, van Rooijen N, Ghaffari S, Grady RW, Giardina P, et al. Removal of Macrophages From the Erythroid Niche Impairs Stress Erythropoiesis but Improves Pathophysiology of Polycythemia Vera and Beta-Thalassemia Blood. 120: 81-81. DOI: 10.1182/BLOOD.V120.21.81.81 |
0.149 |
|
| 2005 |
Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Lander ES, Mesirov JP. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proceedings of the National Academy of Sciences of the United States of America. 102: 15545-50. PMID 16199517 DOI: 10.1073/Pnas.0506580102 |
0.148 |
|
| 2022 |
Miller P, Fell G, Foy B, Scherer A, Gibson CJ, Sperling AS, Burugula BB, Nakao T, Uddin MM, Warren H, Bry L, Pozdnyakova O, Frigault MJ, Bick AG, Neuberg D, ... ... Ebert BL, et al. Clonal Hematopoiesis of Indeterminate Potential and Risk of Death from COVID-19. Blood. PMID 36096050 DOI: 10.1182/blood.2022018052 |
0.148 |
|
| 2022 |
Levin MG, Nakao T, Zekavat SM, Koyama S, Bick AG, Niroula A, Ebert B, Damrauer SM, Natarajan P. Genetics of smoking and risk of clonal hematopoiesis. Scientific Reports. 12: 7248. PMID 35508625 DOI: 10.1038/s41598-022-09604-z |
0.147 |
|
| 2014 |
Raiser DM, Schenone M, Hartman E, Carr SA, Ebert BL. A Proteomics Screen Identifies MDM2 Binding Partners Specific to Ribosomal Protein Haploinsufficiency Blood. 124: 1597-1597. DOI: 10.1182/blood.v124.21.1597.1597 |
0.146 |
|
| 2012 |
Ghisolfi L, Dutt S, McConkey ME, Ebert BL, Anderson P. Stress granules contribute to α-globin homeostasis in differentiating erythroid cells. Biochemical and Biophysical Research Communications. 420: 768-74. PMID 22452989 DOI: 10.1016/J.Bbrc.2012.03.070 |
0.145 |
|
| 2018 |
Wolach O, Sellar RS, Martinod K, Cherpokova D, McConkey M, Chappell RJ, Silver AJ, Adams D, Castellano CA, Schneider RK, Padera RF, DeAngelo DJ, Wadleigh M, Steensma DP, Galinsky I, ... ... Ebert BL, et al. Increased neutrophil extracellular trap formation promotes thrombosis in myeloproliferative neoplasms. Science Translational Medicine. 10. PMID 29643232 DOI: 10.1126/Scitranslmed.Aan8292 |
0.144 |
|
| 2020 |
Miller PG, Gibson CJ, Mehta A, Sperling AS, Frederick DT, Manos MP, Miao B, Hacohen N, Hodi FS, Boland GM, Ebert BL. Fitness Landscape of Clonal Hematopoiesis Under Selective Pressure of Immune Checkpoint Blockade. Jco Precision Oncology. 4. PMID 33015529 DOI: 10.1200/PO.20.00186 |
0.143 |
|
| 2011 |
Esrick EB, Xu J, Lin K, McConkey ME, Frisbee A, Poveromo L, Orkin SH, Bradner JE, Ebert BL. Induction of Fetal Hemoglobin by Inactivation of HDAC1 or HDAC2 without Altering Cellular Proliferation Blood. 118: 354-354. DOI: 10.1182/Blood.V118.21.354.354 |
0.141 |
|
| 2021 |
Weeks LD, Marinac CR, Redd RA, Abel GA, Lin AE, Agrawal M, Stone RM, Schrag D, Ebert BL. Age-related Diseases of Inflammation in Myelodysplastic Syndrome and Chronic Myelomonocytic Leukemia. Blood. PMID 34875037 DOI: 10.1182/blood.2021014418 |
0.141 |
|
| 2010 |
Xu J, Sankaran VG, Esrick EB, Ebert BL, Orkin SH. Reactivation of Silenced Human HbF In Adult Mice by Inactivation of BCL11A Blood. 116: 643-643. DOI: 10.1182/Blood.V116.21.643.643 |
0.141 |
|
| 2008 |
Haining WN, Ebert BL, Subrmanian A, Wherry EJ, Eichbaum Q, Evans JW, Mak R, Rivoli S, Pretz J, Angelosanto J, Smutko JS, Walker BD, Kaech SM, Ahmed R, Nadler LM, et al. Identification of an evolutionarily conserved transcriptional signature of CD8 memory differentiation that is shared by T and B cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 1859-68. PMID 18641323 DOI: 10.4049/Jimmunol.181.3.1859 |
0.14 |
|
| 2021 |
Shirasaki R, Matthews GM, Gandolfi S, de Matos Simoes R, Buckley DL, Raja Vora J, Sievers QL, Brüggenthies JB, Dashevsky O, Poarch H, Tang H, Bariteau MA, Sheffer M, Hu Y, Downey-Kopyscinski SL, ... ... Ebert BL, et al. Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins. Cell Reports. 34: 108532. PMID 33406420 DOI: 10.1016/j.celrep.2020.108532 |
0.14 |
|
| 2019 |
Shirasaki R, Gandolfi S, De Matos Simoes R, Matthews GM, Buckley D, Raja J, Sievers QL, Dashevsky O, Poarch H, Tang H, Bariteau M, Sheffer M, Downey-Kopyscinski SL, Hengeveld P, Glassner B, ... ... Ebert BL, et al. Functional Characterization of E3 Ligases and Their Regulators: Therapeutic Implications for Development of New Proteolysis-Targeting Chimeric Degraders of Oncoproteins Blood. 134: 318-318. DOI: 10.1182/Blood-2019-130549 |
0.139 |
|
| 2023 |
Paolino J, Dimitrov B, Apsel Winger B, Sandoval-Perez A, Rangarajan AV, Ocasio-Martinez N, Tsai HK, Li Y, Robichaud AL, Khalid D, Hatton C, Gillani R, Polonen P, Dilig A, Gotti G, ... ... Ebert BL, et al. Integration of genomic sequencing drives therapeutic targeting of PDGFRA in T-cell acute lymphoblastic leukemia/lymphoblastic lymphoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 37725576 DOI: 10.1158/1078-0432.CCR-22-2562 |
0.138 |
|
| 2023 |
Kann MC, Schneider EM, Almazan AJ, Lane IC, Bouffard AA, Supper VM, Takei HN, Tepper A, Leick MB, Larson RC, Ebert BL, Maus MV, Jan M. Chemical genetic control of cytokine signaling in CAR-T cells using lenalidomide-controlled membrane-bound degradable IL-7. Leukemia. PMID 38123696 DOI: 10.1038/s41375-023-02113-6 |
0.136 |
|
| 2021 |
Jan M, Scarfò I, Larson RC, Walker A, Schmidts A, Guirguis AA, Gasser JA, Słabicki M, Bouffard AA, Castano AP, Kann MC, Cabral ML, Tepper A, Grinshpun DE, Sperling AS, ... ... Ebert BL, et al. Reversible ON- and OFF-switch chimeric antigen receptors controlled by lenalidomide. Science Translational Medicine. 13. PMID 33408186 DOI: 10.1126/scitranslmed.abb6295 |
0.136 |
|
| 2023 |
Bourgeois W, Cutler JA, Aubrey BJ, Wenge D, Perner F, Martucci C, Henrich JA, Klega K, Nowak RP, Donovan KA, Boileau M, Wen Y, Hatton C, Apazidis AA, Olsen SN, ... ... Ebert BL, et al. Mezigdomide is effective alone and in combination with Menin inhibition in pre-clinical models of KMT2A-r and NPM1c AML. Blood. PMID 38096371 DOI: 10.1182/blood.2023021105 |
0.135 |
|
| 2019 |
Garcia JS, Bhatt S, Fell G, Sperling AS, Burgess M, Keshishian H, Yilma B, Brunner A, Neuberg D, Carr SA, Ebert BL, Ballen K, Stone RM, DeAngelo DJ, Medeiros BC, et al. Increased mitochondrial apoptotic priming with targeted therapy predicts clinical response to re-induction chemotherapy. American Journal of Hematology. PMID 31804723 DOI: 10.1002/Ajh.25692 |
0.134 |
|
| 2024 |
Saadatagah S, Uddin MM, Weeks LD, Niroula A, Ru M, Takahashi K, Gondek L, Yu B, Bick AG, Ebert BL, Platz EA, Natarajan P, Ballantyne CM. Clonal Hematopoiesis Risk Score and All-Cause and Cardiovascular Mortality in Older Adults. Jama Network Open. 7: e2351927. PMID 38231513 DOI: 10.1001/jamanetworkopen.2023.51927 |
0.133 |
|
| 2013 |
Vlachos A, Farrar JE, Atsidaftos E, Muir E, Narla A, Markello TC, Singh SA, Landowski M, Gazda HT, Blanc L, Liu JM, Ellis SR, Arceci RJ, Ebert BL, Bodine DM, et al. Diminutive somatic deletions in the 5q region lead to a phenotype atypical of classical 5q- syndrome. Blood. 122: 2487-90. PMID 23943650 DOI: 10.1182/Blood-2013-06-509935 |
0.133 |
|
| 2021 |
Renneville A, Gasser JA, Grinshpun DE, Jean Beltran PM, Udeshi ND, Matyskiela ME, Clayton T, McConkey M, Viswanathan K, Tepper A, Guirguis AA, Sellar RS, Cotteret S, Marzac C, Saada V, ... ... Ebert BL, et al. Avadomide induces degradation of ZMYM2 fusion oncoproteins in hematologic malignancies. Blood Cancer Discovery. 2: 250-265. PMID 34027417 DOI: 10.1158/2643-3230.bcd-20-0105 |
0.132 |
|
| 2010 |
Mullally A, Ebert BL. NF1 inactivation revs up Ras in adult acute myelogenous leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 4074-6. PMID 20587590 DOI: 10.1158/1078-0432.CCR-10-1438 |
0.132 |
|
| 2008 |
Ebert BL, Galili N, Tamayo P, Bosco J, Mak R, Pretz J, Tanguturi S, Ladd-Acosta C, Stone R, Golub TR, Raza A. An erythroid differentiation signature predicts response to lenalidomide in myelodysplastic syndrome. Plos Medicine. 5: e35. PMID 18271621 DOI: 10.1371/journal.pmed.0050035 |
0.13 |
|
| 2022 |
Tian R, Wiley B, Liu J, Zong X, Truong B, Zhao S, Uddin MM, Niroula A, Miller CA, Mukherjee S, Heiden BT, Luo J, Puri V, Kozower BD, Walter MJ, ... ... Ebert BL, et al. Clonal Hematopoiesis and Risk of Incident Lung Cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2200857. PMID 36480766 DOI: 10.1200/JCO.22.00857 |
0.13 |
|
| 2021 |
Renneville A, Gasser JA, Grinshpun DE, Jean Beltran PM, Udeshi ND, Matyskiela ME, Clayton T, McConkey M, Viswanathan K, Tepper A, Guirguis AA, Sellar RS, Cotteret S, Marzac C, Saada V, ... ... Ebert BL, et al. Avadomide Induces Degradation of ZMYM2 Fusion Oncoproteins in Hematologic Malignancies. Cancer Discovery. 2: 250-265. PMID 34233287 DOI: 10.1158/2643-3230.BCD-20-0105 |
0.129 |
|
| 2011 |
Järås M, Ebert BL. Power cut: inhibiting mitochondrial translation to target leukemia. Cancer Cell. 20: 555-6. PMID 22094249 DOI: 10.1016/j.ccr.2011.10.028 |
0.129 |
|
| 2018 |
Sievers QL, Gasser JA, Cowley GS, Fischer ES, Ebert BL. Genome-wide screen identifies cullin-RING ligase machinery required for lenalidomide-dependent CRL4 activity. Blood. PMID 30042095 DOI: 10.1182/blood-2018-01-821769 |
0.128 |
|
| 2017 |
Miller PG, Ebert BL. Leukaemia: Vitamin C regulates stem cells and cancer. Nature. PMID 28869971 DOI: 10.1038/nature23548 |
0.128 |
|
| 2011 |
Elkabets M, Gifford AM, Scheel C, Nilsson B, Reinhardt F, Bray MA, Carpenter AE, Jirström K, Magnusson K, Ebert BL, Pontén F, Weinberg RA, McAllister SS. Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice. The Journal of Clinical Investigation. 121: 784-99. PMID 21266779 DOI: 10.1172/Jci43757 |
0.127 |
|
| 2017 |
Tothova Z, Ebert BL. Doubling Down on Mutant RAS Can MEK or Break Leukemia. Cell. 168: 749-750. PMID 28235190 DOI: 10.1016/j.cell.2017.02.013 |
0.126 |
|
| 2009 |
Kumar M, Narla A, Nonami A, Ball B, Chin C, Chen C, Kutok JL, Galili N, Raza A, Attar EC, GIlliland DG, Jacks T, Ebert BL. Coordinate Loss of a MicroRNA Mir 145 and a Protein-Coding Gene RPS14 Cooperate in the Pathogenesis of 5q- Syndrome. Blood. 114: 947-947. DOI: 10.1182/Blood.V114.22.947.947 |
0.126 |
|
| 2018 |
Stroopinsky D, Liegel J, Mahoney KM, Rosenblatt J, Ebert BL, Stone RM, Rahimian M, Nahas M, Orr S, Capelletti M, Weinstock M, Jain S, Bisharat L, Ghiasuddin H, Morin A, et al. A Novel Monoclonal Antibody Combination Plus DC/AML Fusion Vaccine Eradicates AML in an Immunocompetent Murine Model Blood. 132: 1446-1446. DOI: 10.1182/BLOOD-2018-99-120259 |
0.125 |
|
| 2018 |
Sperling AS, Burgess M, Keshishian H, Gasser J, Jan M, Sharma R, Fulciniti M, Munshi N, Carr SA, Ebert BL. Discovery of a Novel Mechanism of Resistance to Thalidomide Derivatives Blood. 132: 949-949. DOI: 10.1182/Blood-2018-99-115110 |
0.125 |
|
| 2014 |
Krönke J, Hurst SN, Ebert BL. Lenalidomide induces degradation of IKZF1 and IKZF3. Oncoimmunology. 3: e941742. PMID 25610725 DOI: 10.4161/21624011.2014.941742 |
0.124 |
|
| 2011 |
Ebert BL. Molecular dissection of the 5q deletion in myelodysplastic syndrome. Seminars in Oncology. 38: 621-6. PMID 21943668 DOI: 10.1053/j.seminoncol.2011.04.010 |
0.124 |
|
| 1998 |
Ebert BL, Bunn HF. Regulation of transcription by hypoxia requires a multiprotein complex that includes hypoxia-inducible factor 1, an adjacent transcription factor, and p300/CREB binding protein. Molecular and Cellular Biology. 18: 4089-96. PMID 9632793 DOI: 10.1128/MCB.18.7.4089 |
0.123 |
|
| 2013 |
Komrokji RS, Padron E, Ebert BL, List AF. Deletion 5q MDS: molecular and therapeutic implications. Best Practice & Research. Clinical Haematology. 26: 365-75. PMID 24507813 DOI: 10.1016/J.Beha.2013.10.013 |
0.123 |
|
| 2022 |
Rauch PJ, Ebert BL. Leukemia and Heart Disease: Lessons at the Intersection of the Most Feared CHIP Outcomes. Jacc. Cardiooncology. 4: 50-52. PMID 35492812 DOI: 10.1016/j.jaccao.2022.01.094 |
0.122 |
|
| 2009 |
Quigley M, Pereyra F, Nilsson B, Eichbaum Q, Julg B, Jesneck J, Brosnahan K, Russell K, Toth I, Piechocka-Trocha A, Shin H, Freeman GJ, Wherry EJ, Walker BD, Ebert BL, et al. Integrative Genomic Analysis of HIV-Specific CD8+ T Cells Reveals That PD-1 Inhibits T Cell Function by Upregulating the AP-1 Transcription Factor BATF. Blood. 114: 916-916. DOI: 10.1182/Blood.V114.22.916.916 |
0.122 |
|
| 2018 |
Libby P, Ebert BL. CHIP (Clonal Hematopoiesis of Indeterminate Potential). Circulation. 138: 666-668. PMID 30359133 DOI: 10.1161/CIRCULATIONAHA.118.034392 |
0.122 |
|
| 2015 |
Krönke J, Fink EC, Hollenbach PW, MacBeth KJ, Hurst SN, Udeshi ND, Chamberlain PP, Mani DR, Man HW, Gandhi AK, Svinkina T, Schneider RK, McConkey M, Järås M, Griffiths E, ... ... Ebert BL, et al. Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS. Nature. 523: 183-8. PMID 26131937 DOI: 10.1038/Nature14610 |
0.121 |
|
| 2024 |
Molinaro R, Sellar RS, Vromman A, Sausen G, Folco E, Sukhova GK, McConke ME, Corbo C, Ebert BL, Libby P. The clonal hematopoiesis mutation Jak2 aggravates endothelial injury and thrombosis in arteries with erosion-like intimas. International Journal of Cardiology. 132184. PMID 38759798 DOI: 10.1016/j.ijcard.2024.132184 |
0.12 |
|
| 2024 |
Tsai JM, Nowak RP, Ebert BL, Fischer ES. Targeted protein degradation: from mechanisms to clinic. Nature Reviews. Molecular Cell Biology. PMID 38684868 DOI: 10.1038/s41580-024-00729-9 |
0.12 |
|
| 2009 |
Cheung KJ, Ebert BL. Therapeutic potential of targeting haploinsufficient genes in cancer. Pediatric Blood & Cancer. 53: 131-2. PMID 19343773 DOI: 10.1002/pbc.22019 |
0.119 |
|
| 2015 |
Okam MM, Esrick EB, Mandell E, Campigotto F, Neuberg DS, Ebert BL. Phase 1/2 trial of vorinostat in patients with sickle cell disease who have not benefitted from hydroxyurea. Blood. 125: 3668-9. PMID 26045597 DOI: 10.1182/blood-2015-03-635391 |
0.118 |
|
| 2019 |
Shirasaki R, de Matos Simoes R, Gandolfi S, Matthews G, Buckley D, Raja J, Sievers Q, Bruggenthies J, Dashevsky O, Poarch H, Tang H, Bariteau M, Sheffer M, Hu Y, Downey-Kopyscinski S, ... ... Ebert B, et al. Molecular markers of myeloma cell sensitivity vs. resistance to heterobifunctional degraders of oncoproteins: therapeutic implications. Clinical Lymphoma Myeloma and Leukemia. 19: e134. DOI: 10.1016/J.Clml.2019.09.222 |
0.118 |
|
| 2016 |
Townsend EC, Murakami MA, Christodoulou A, Christie AL, Köster J, DeSouza TA, Morgan EA, Kallgren SP, Liu H, Wu SC, Plana O, Montero J, Stevenson KE, Rao P, Vadhi R, ... ... Ebert BL, et al. The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice. Cancer Cell. 29: 574-86. PMID 27070704 DOI: 10.1016/J.Ccell.2016.03.008 |
0.117 |
|
| 2014 |
Narla A, Payne EM, Abayasekara N, Hurst SN, Raiser DM, Look AT, Berliner N, Ebert BL, Khanna-Gupta A. L-Leucine improves the anaemia in models of Diamond Blackfan anaemia and the 5q- syndrome in a TP53-independent way. British Journal of Haematology. 167: 524-8. PMID 25098371 DOI: 10.1111/Bjh.13069 |
0.117 |
|
| 2022 |
Arber DA, Orazi A, Hasserjian RP, Borowitz MJ, Calvo KR, Kvasnicka HM, Wang SA, Bagg A, Barbui T, Branford S, Bueso-Ramos CE, Cortes J, Dal Cin P, DiNardo CD, Dombret H, ... ... Ebert BL, et al. International Consensus Classification of Myeloid Neoplasms and Acute Leukemia: Integrating Morphological, Clinical, and Genomic Data. Blood. PMID 35767897 DOI: 10.1182/blood.2022015850 |
0.116 |
|
| 2019 |
Struntz NB, Chen A, Deutzmann A, Wilson RM, Stefan E, Evans HL, Ramirez MA, Liang T, Caballero F, Wildschut MHE, Neel DV, Freeman DB, Pop MS, McConkey M, Muller S, ... ... Ebert BL, et al. Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription. Cell Chemical Biology. PMID 30880155 DOI: 10.1016/J.Chembiol.2019.02.009 |
0.116 |
|
| 2016 |
Sievers Q, Gasser J, Cowley G, Doench JG, Fischer E, Ebert BL. Genome-Scale Screen Reveals Genes Required for Lenalidomide-Mediated Degradation of Aiolos By CRL4-CRBN Blood. 128: 5139-5139. DOI: 10.1182/blood.v128.22.5139.5139 |
0.115 |
|
| 2011 |
Shah DI, Takahashi-Makise N, Cooney JD, Li L, Schultz I, Pierce EL, Narla A, Hattangadi S, Langer N, Chen W, Dailey TA, Hurst SN, Faccenda D, Wiwczar J, Law TC, ... ... Ebert BL, et al. Mitochondrial Atpif1 Regulates Heme Synthesis in Developing Erythroblasts Blood. 118: 343-343. DOI: 10.1182/Blood.V118.21.343.343 |
0.115 |
|
| 2018 |
Schneider RK, Mullally A, Dugourd A, Peisker F, Hoogenboezem R, Van Strien PMH, Bindels EM, Heckl D, Büsche G, Fleck D, Müller-Newen G, Wongboonsin J, Ventura Ferreira M, Puelles VG, Saez-Rodriguez J, ... Ebert BL, et al. Gli1 Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target. Cell Stem Cell. 23: 308-309. PMID 30075132 DOI: 10.1016/J.Stem.2018.07.006 |
0.115 |
|
| 2011 |
Narla A, Hurst SN, Ebert BL. Ribosome defects in disorders of erythropoiesis. International Journal of Hematology. 93: 144-149. PMID 21279816 DOI: 10.1007/s12185-011-0776-0 |
0.115 |
|
| 2012 |
Payne EM, Virgilio M, Narla A, Sun H, Levine M, Paw BH, Berliner N, Look AT, Ebert BL, Khanna-Gupta A. L-Leucine improves the anemia and developmental defects associated with Diamond-Blackfan anemia and del(5q) MDS by activating the mTOR pathway. Blood. 120: 2214-24. PMID 22734070 DOI: 10.1182/Blood-2011-10-382986 |
0.112 |
|
| 2020 |
Słabicki M, Yoon H, Koeppel J, Nitsch L, Roy Burman SS, Di Genua C, Donovan KA, Sperling AS, Hunkeler M, Tsai JM, Sharma R, Guirguis A, Zou C, Chudasama P, Gasser JA, ... ... Ebert BL, et al. Small-molecule-induced polymerization triggers degradation of BCL6. Nature. PMID 33208943 DOI: 10.1038/s41586-020-2925-1 |
0.11 |
|
| 2021 |
Bernard E, Nannya Y, Hasserjian RP, Devlin SM, Tuechler H, Medina-Martinez JS, Yoshizato T, Shiozawa Y, Saiki R, Malcovati L, Levine MF, Arango JE, Zhou Y, Solé F, Cargo CA, ... ... Ebert BL, et al. Author Correction: Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes. Nature Medicine. PMID 33948021 DOI: 10.1038/s41591-021-01367-w |
0.109 |
|
| 2021 |
Bernard E, Nannya Y, Hasserjian RP, Devlin SM, Tuechler H, Medina-Martinez JS, Yoshizato T, Shiozawa Y, Saiki R, Malcovati L, Levine MF, Arango JE, Zhou Y, Solé F, Cargo CA, ... ... Ebert BL, et al. Author Correction: Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes. Nature Medicine. PMID 33564192 DOI: 10.1038/s41591-021-01253-5 |
0.109 |
|
| 2007 |
Tamayo P, Scanfeld D, Ebert BL, Gillette MA, Roberts CW, Mesirov JP. Metagene projection for cross-platform, cross-species characterization of global transcriptional states. Proceedings of the National Academy of Sciences of the United States of America. 104: 5959-64. PMID 17389406 DOI: 10.1073/Pnas.0701068104 |
0.107 |
|
| 2021 |
Stroopinsky D, Liegel J, Bhasin M, Cheloni G, Thomas B, Bhasin S, Panchal R, Ghiasuddin H, Rahimian M, Nahas M, Orr S, Capelletti M, Torres D, Tacettin C, Weinstock M, ... ... Ebert B, et al. Leukemia vaccine overcomes limitations of checkpoint blockade by evoking clonal T cell responses in a murine acute myeloid leukemia model. Haematologica. PMID 33538148 DOI: 10.3324/haematol.2020.259457 |
0.107 |
|
| 2007 |
Yang H, Minamishima YA, Yan Q, Schlisio S, Ebert BL, Zhang X, Zhang L, Kim WY, Olumi AF, Kaelin WG. pVHL acts as an adaptor to promote the inhibitory phosphorylation of the NF-kappaB agonist Card9 by CK2. Molecular Cell. 28: 15-27. PMID 17936701 DOI: 10.1016/J.Molcel.2007.09.010 |
0.107 |
|
| 2016 |
Lechman ER, Gentner B, Ng SW, Schoof EM, van Galen P, Kennedy JA, Nucera S, Ciceri F, Kaufmann KB, Takayama N, Dobson SM, Trotman-Grant A, Krivdova G, Elzinga J, Mitchell A, ... ... Ebert BL, et al. miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells. Cancer Cell. PMID 26832662 DOI: 10.1016/J.Ccell.2015.12.011 |
0.106 |
|
| 2018 |
List A, Ebert BL, Fenaux P. A decade of progress in myelodysplastic syndrome with chromosome 5q deletion. Leukemia. 32: 1493-1499. PMID 29445113 DOI: 10.1038/S41375-018-0029-9 |
0.106 |
|
| 2015 |
Lindsley R, Mar B, Mazzola E, Grauman P, Lindeman N, Steensma D, DeAngelo D, Wadleigh M, Neuberg D, Stone R, Ebert B. 19 AN OBJECTIVE GENETIC ONTOGENY CLASSIFICATION IDENTIFIES TRUE BIOLOGICAL SECONDARY AML AMONG DE NOVO AML PATIENTS ≥60 YEARS OLD Leukemia Research. 39: S8. DOI: 10.1016/S0145-2126(15)30020-5 |
0.105 |
|
| 2016 |
Lechman ER, Gentner B, Ng SW, Schoof EM, van Galen P, Kennedy JA, Nucera S, Ciceri F, Kaufmann KB, Takayama N, Dobson SM, Trotman-Grant A, Krivdova G, Elzinga J, Mitchell A, ... ... Ebert BL, et al. miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells. Cancer Cell. 29: 602-606. PMID 27070706 DOI: 10.1016/J.Ccell.2016.03.015 |
0.104 |
|
| 1999 |
Ebert BL, Bunn HF. Regulation of the Erythropoietin Gene Blood. 94: 1864-1877. DOI: 10.1182/blood.V94.6.1864.418k37_1864_1877 |
0.104 |
|
| 2024 |
Saadatagah S, Naderian M, Uddin M, Dikilitas O, Niroula A, Schuermans A, Selvin E, Hoogeveen RC, Matsushita K, Nambi V, Yu B, Chen LY, Bick AG, Ebert BL, Honigberg MC, et al. Atrial Fibrillation and Clonal Hematopoiesis in TET2 and ASXL1. Jama Cardiology. PMID 38598228 DOI: 10.1001/jamacardio.2024.0459 |
0.104 |
|
| 2020 |
Udeshi ND, Mani DC, Satpathy S, Fereshetian S, Gasser JA, Svinkina T, Olive ME, Ebert BL, Mertins P, Carr SA. Rapid and deep-scale ubiquitylation profiling for biology and translational research. Nature Communications. 11: 359. PMID 31953384 DOI: 10.1038/S41467-019-14175-1 |
0.103 |
|
| 2017 |
Ebert BL, Friedberg JW. Introduction to Genomics in Hematologic Malignancy. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 35: 927-928. PMID 28297621 DOI: 10.1200/JCO.2017.72.2827 |
0.103 |
|
| 2022 |
Koochaki SHJ, Słabicki M, Lumpkin R, Zou C, Belizaire R, Fischer ES, Ebert BL. A STUB1 ubiquitin ligase/CHIC2 protein complex negatively regulates the IL-3, IL-5, and GM-CSF cytokine receptor common β chain (CSF2RB) protein stability. The Journal of Biological Chemistry. 102484. PMID 36108743 DOI: 10.1016/j.jbc.2022.102484 |
0.103 |
|
| 2021 |
Jan M, Sperling AS, Ebert BL. Cancer therapies based on targeted protein degradation - lessons learned with lenalidomide. Nature Reviews. Clinical Oncology. PMID 33654306 DOI: 10.1038/s41571-021-00479-z |
0.103 |
|
| 2011 |
Kumar MS, Narla A, Nonami A, Mullally A, Dimitrova N, Ball B, McAuley JR, Poveromo L, Kutok JL, Galili N, Raza A, Attar E, Gilliland DG, Jacks T, Ebert BL. Coordinate loss of a microRNA and protein-coding gene cooperate in the pathogenesis of 5q- syndrome. Blood. 118: 4666-73. PMID 21873545 DOI: 10.1182/Blood-2010-12-324715 |
0.102 |
|
| 2019 |
Ribezzo F, Snoeren IAM, Ziegler S, Stoelben J, Olofsen PA, Henic A, Ferreira MV, Chen S, Stalmann USA, Buesche G, Hoogenboezem RM, Kramann R, Platzbecker U, Raaijmakers MHGP, Ebert BL, et al. Rps14, Csnk1a1 and miRNA145/miRNA146a deficiency cooperate in the clinical phenotype and activation of the innate immune system in the 5q- syndrome. Leukemia. PMID 30651631 DOI: 10.1038/s41375-018-0350-3 |
0.1 |
|
| 2013 |
Vlachos A, Farrar J, Atsidaftos E, Muir E, Narla A, Markello T, Singh S, Blanc L, Landowski M, Gazda H, Liu J, Ellis S, Arceci R, Ebert B, Bodine D, et al. P-083 5q-syndrome or diamond blackfan anemia: The perplexing diagnostic puzzle of red cell aplasia Leukemia Research. 37: S59. DOI: 10.1016/S0145-2126(13)70132-2 |
0.1 |
|
| 2018 |
Steensma DP, Ebert BL. Clonal Hematopoiesis after Induction Chemotherapy for Acute Myeloid Leukemia. The New England Journal of Medicine. 378: 1244-1245. PMID 29590545 DOI: 10.1056/NEJMe1802610 |
0.1 |
|
| 2022 |
Murawska GM, Vogel C, Jan M, Lu X, Schild M, Slabicki M, Zou C, Zhanybekova S, Manojkumar M, Petzold G, Kaiser P, Thomä N, Ebert B, Gillingham D. Repurposing the Damage Repair Protein Methyl Guanine Methyl Transferase as a Ligand Inducible Fusion Degron. Acs Chemical Biology. PMID 34982531 DOI: 10.1021/acschembio.1c00771 |
0.097 |
|
| 2017 |
DeAngelo DJ, Brunner AM, Werner L, Avigan D, Fathi AT, Sperling AS, Washington A, Stroopinsky D, Rosenblatt J, McMasters M, Luptakova K, Wadleigh M, Steensma DP, Hobbs GS, Attar EC, ... ... Ebert BL, et al. A Phase I Study of Lenalidomide plus Chemotherapy with Mitoxantrone, Etoposide, and Cytarabine for the Reinduction of Patients with Acute Myeloid Leukemia. American Journal of Hematology. PMID 29119643 DOI: 10.1002/ajh.24968 |
0.097 |
|
| 2012 |
Shah DI, Takahashi-Makise N, Cooney JD, Li L, Schultz IJ, Pierce EL, Narla A, Seguin A, Hattangadi SM, Medlock AE, Langer NB, Dailey TA, Hurst SN, Faccenda D, Wiwczar JM, ... ... Ebert BL, et al. Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts. Nature. 491: 608-12. PMID 23135403 DOI: 10.1038/Nature11536 |
0.095 |
|
| 2019 |
Sperling AS, Burgess M, Keshishian H, Gasser JA, Bhatt S, Jan M, Słabicki M, Sellar RS, Fink EC, Miller PG, Liddicoat BJ, Sievers QL, Sharma R, Adams DN, Olesinski EA, ... ... Ebert BL, et al. Patterns of substrate affinity, competition and degradation kinetics underlie biological activity of thalidomide analogs. Blood. PMID 31043423 DOI: 10.1182/Blood.2019000789 |
0.094 |
|
| 2015 |
Guirguis AA, Ebert BL. Lenalidomide: deciphering mechanisms of action in myeloma, myelodysplastic syndrome and beyond. Current Opinion in Cell Biology. 37: 61-7. PMID 26512454 DOI: 10.1016/j.ceb.2015.10.004 |
0.093 |
|
| 2021 |
Teng M, Lu W, Donovan KA, Sun J, Krupnick NM, Nowak RP, Li YD, Sperling AS, Zhang T, Ebert BL, Fischer ES, Gray NS. Development of PDE6D and CK1α Degraders through Chemical Derivatization of FPFT-2216. Journal of Medicinal Chemistry. PMID 34965125 DOI: 10.1021/acs.jmedchem.1c01832 |
0.092 |
|
| 2020 |
Słabicki M, Kozicka Z, Petzold G, Li YD, Manojkumar M, Bunker RD, Donovan KA, Sievers QL, Koeppel J, Suchyta D, Sperling AS, Fink EC, Gasser JA, Wang LR, Corsello SM, ... ... Ebert BL, et al. The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K. Nature. PMID 32494016 DOI: 10.1038/S41586-020-2374-X |
0.09 |
|
| 2022 |
Sekar A, Ebert BL. Blood's life history traced through genomic scars. Nature. 606: 255-256. PMID 35650394 DOI: 10.1038/d41586-022-01304-y |
0.089 |
|
| 2008 |
Zimmer M, Ebert BL, Neil C, Brenner K, Papaioannou I, Melas A, Tolliday N, Lamb J, Pantopoulos K, Golub T, Iliopoulos O. Small-molecule inhibitors of HIF-2a translation link its 5'UTR iron-responsive element to oxygen sensing. Molecular Cell. 32: 838-48. PMID 19111663 DOI: 10.1016/J.Molcel.2008.12.004 |
0.087 |
|
| 2023 |
Zou C, Yoon H, Park PMC, Patten JJ, Pellman J, Carreiro J, Tsai JM, Li YD, Roy Burman SS, Donovan KA, Gasser J, Sperling AS, Nowak RP, Fischer ES, Davey RA, ... Ebert BL, et al. The human E3 ligase RNF185 is a regulator of the SARS-CoV-2 envelope protein. Iscience. 26: 106601. PMID 37095859 DOI: 10.1016/j.isci.2023.106601 |
0.087 |
|
| 2018 |
Boettcher S, Ebert BL. Clonal Hematopoiesis of Indeterminate Potential. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2018793588. PMID 30589599 DOI: 10.1200/JCO.2018.79.3588 |
0.085 |
|
| 2023 |
Sreekanth V, Jan M, Zhao KT, Lim D, Davis JR, McConkey M, Kovalcik V, Barkal S, Law BK, Fife J, Tian R, Vinyard ME, Becerra B, Kampmann ME, Sherwood RI, ... ... Ebert BL, et al. A molecular glue approach to control the half-life of CRISPR-based technologies. Biorxiv : the Preprint Server For Biology. PMID 36945568 DOI: 10.1101/2023.03.12.531757 |
0.085 |
|
| 2013 |
Ramos P, Casu C, Gardenghi S, Breda L, Crielaard BJ, Guy E, Marongiu MF, Gupta R, Levine RL, Abdel-Wahab O, Ebert BL, Van Rooijen N, Ghaffari S, Grady RW, Giardina PJ, et al. Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia. Nature Medicine. 19: 437-45. PMID 23502961 DOI: 10.1038/nm.3126 |
0.083 |
|
| 2023 |
Li YD, Ma MW, Hassan MM, Hunkeler M, Teng M, Puvar K, Lumpkin R, Sandoval B, Jin CY, Ficarro SB, Wang MY, Xu S, Groendyke BJ, Sigua LH, Tavares I, ... ... Ebert BL, et al. Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders. Biorxiv : the Preprint Server For Biology. PMID 36824856 DOI: 10.1101/2023.02.14.528208 |
0.082 |
|
| 2008 |
Lu J, Guo S, Ebert BL, Zhang H, Peng X, Bosco J, Pretz J, Schlanger R, Wang JY, Mak RH, Dombkowski DM, Preffer FI, Scadden DT, Golub TR. MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitors. Developmental Cell. 14: 843-53. PMID 18539114 DOI: 10.1016/J.Devcel.2008.03.012 |
0.079 |
|
| 2024 |
Yoon H, Rutter JC, Li YD, Ebert BL. Induced protein degradation for therapeutics: past, present, and future. The Journal of Clinical Investigation. 134. PMID 38165043 DOI: 10.1172/JCI175265 |
0.076 |
|
| 2023 |
Nakao T, Yu Z, Vlasschaert C, Uddin MM, Lindsay ME, Ellinor PT, Ebert BL, Bick AG, Pirruccello JP, Natarajan P. Increased Risk of Thoracic Aortic Aneurysms With JAK2 V617F. Journal of the American College of Cardiology. 81: 2128-2130. PMID 37225367 DOI: 10.1016/j.jacc.2023.03.413 |
0.075 |
|
| 2020 |
Jan M, Grinshpun DE, Villalba JA, Dal Cin P, Sykes DB, Iafrate AJ, Ebert BL, Hobbs GS, Nardi V. A cryptic imatinib-sensitive G3BP1-PDGFRB rearrangement in a myeloid neoplasm with eosinophilia. Blood Advances. 4: 445-448. PMID 31999327 DOI: 10.1182/Bloodadvances.2019001182 |
0.075 |
|
| 2023 |
Nguyen TM, Sreekanth V, Deb A, Kokkonda P, Tiwari PK, Donovan KA, Shoba V, Chaudhary SK, Mercer JAM, Lai S, Sadagopan A, Jan M, Fischer ES, Liu DR, Ebert BL, et al. Proteolysis-targeting chimeras with reduced off-targets. Nature Chemistry. PMID 38110475 DOI: 10.1038/s41557-023-01379-8 |
0.074 |
|
| 2018 |
Sievers QL, Petzold G, Bunker RD, Renneville A, Słabicki M, Liddicoat BJ, Abdulrahman W, Mikkelsen T, Ebert BL, Thomä NH. Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN. Science (New York, N.Y.). 362. PMID 30385546 DOI: 10.1126/science.aat0572 |
0.073 |
|
| 2015 |
Schneider R, Schenone M, Chen M, Waters C, McConkey M, Lindsley R, Ebert B. 36 TERMINAL ERYTHROID DIFFERENTIATION DEFECT AND ACTIVATION OF THE INNATE IMMUNE SYSTEM IN MICE WITH RIBOSOMAL PROTEIN S14 HAPLOINSUFFICIENCY Leukemia Research. 39: S16. DOI: 10.1016/S0145-2126(15)30037-0 |
0.072 |
|
| 2009 |
Nilsson B, Johansson M, Al-Shahrour F, Carpenter AE, Ebert BL. Ultrasome: efficient aberration caller for copy number studies of ultra-high resolution. Bioinformatics (Oxford, England). 25: 1078-9. PMID 19228802 DOI: 10.1093/Bioinformatics/Btp091 |
0.07 |
|
| 2023 |
Hassan MM, Li YD, Ma MW, Teng M, Byun WS, Puvar K, Lumpkin R, Sandoval B, Rutter JC, Jin CY, Wang MY, Xu S, Schmoker AM, Cheong H, Groendyke BJ, ... ... Ebert BL, et al. Exploration of the Tunability of BRD4 Degradation by DCAF16 -labelling Covalent Glues. Biorxiv : the Preprint Server For Biology. PMID 37873358 DOI: 10.1101/2023.10.07.561308 |
0.07 |
|
| 2019 |
Mouhieddine T, Tahri S, Park J, Redd R, Leventhal M, Gibson C, Sperling AS, Manier S, Nassar A, Capelletti M, Huynh D, Bustoros M, Sklavenitis-Pistofidis R, Hornburg K, Dumke H, ... ... Ebert B, et al. Immunomodulatory therapy improves outcome in multiple myeloma patients with clonal hematopoiesis Clinical Lymphoma Myeloma and Leukemia. 19: e15. DOI: 10.1016/j.clml.2019.09.021 |
0.07 |
|
| 2021 |
Narla A, Ruddy KJ, Ebert BL, Mar B. Whole exome sequencing of a breast tumor in a patient with Diamond Blackfan anemia. Blood Cells, Molecules & Diseases. 89: 102566. PMID 33862369 DOI: 10.1016/j.bcmd.2021.102566 |
0.068 |
|
| 2020 |
Richards M, Anderson M, Carter P, Ebert BL, Mossialos E. The impact of the COVID-19 pandemic on cancer care. Nature Cancer. 1: 565-567. PMID 32838302 DOI: 10.1038/s43018-020-0074-y |
0.067 |
|
| 2003 |
Ebert BL, Niemierko E, Shaffer K, Salgia R. Use of temozolomide with other cytotoxic chemotherapy in the treatment of patients with recurrent brain metastases from lung cancer Oncologist. 8: 69-75. PMID 12604733 DOI: 10.1634/Theoncologist.8-1-69 |
0.067 |
|
| 2023 |
AlJabban A, Paik H, Aster JC, Berliner N, Brouillard J, Brown JR, Burns KH, Castillo JJ, Card J, Dal Cin P, DeAngelo DJ, Dorfman DM, Ebert BL, Garcia JS, Jacobson CA, et al. Optimization of Advanced Molecular Genetic Testing Utilization in Hematopathology: A Goldilocks Approach to Bone Marrow Testing. Jco Oncology Practice. OP2300217. PMID 37683132 DOI: 10.1200/OP.23.00217 |
0.066 |
|
| 2016 |
Ventura Ferreira MS, Bergmann C, Bodensiek I, Peukert K, Abert J, Kramann R, Kachel P, Rath B, Rütten S, Knuchel R, Ebert BL, Fischer H, Brümmendorf TH, Schneider RK. An engineered multicomponent bone marrow niche for the recapitulation of hematopoiesis at ectopic transplantation sites. Journal of Hematology & Oncology. 9: 4. PMID 26810307 DOI: 10.1186/s13045-016-0234-9 |
0.066 |
|
| 2016 |
Ventura Ferreira MS, Bergmann C, Bodensiek I, Peukert K, Abert J, Kramann R, Kachel P, Rath B, Rütten S, Knuchel R, Ebert BL, Fischer H, Brümmendorf TH, Schneider RK. An engineered multicomponent bone marrow niche for the recapitulation of hematopoiesis at ectopic transplantation sites Journal of Hematology and Oncology. DOI: 10.1186/s13045-016-0234-9 |
0.065 |
|
| 2023 |
Sarott RC, You I, Li YD, Toenjes ST, Donovan KA, Seo P, Ordonez M, Byun WS, Hassan MM, Wachter F, Chouchani ET, Słabicki M, Fischer ES, Ebert BL, Hinshaw SM, et al. Chemical Specification of E3 Ubiquitin Ligase Engagement by Cysteine-Reactive Chemistry. Journal of the American Chemical Society. PMID 37767920 DOI: 10.1021/jacs.3c06622 |
0.064 |
|
| 2013 |
Steensma DP, Ebert BL. Initial experience with L-leucine therapy in myelodysplastic syndromes with associated chromosome 5q deletion. Blood. 121: 4428. PMID 23704049 DOI: 10.1182/blood-2013-03-493809 |
0.063 |
|
| 2020 |
Miller PG, Sperling AS, Gibson CJ, Pozdnyakova O, Wong WJ, Manos MP, Buchbinder EI, Hodi FS, Ebert BL, Davids MS. A deep molecular response of splenic marginal zone lymphoma to front-line checkpoint blockade. Haematologica. PMID 33054119 DOI: 10.3324/Haematol.2020.258426 |
0.062 |
|
| 2023 |
Tsai JM, Aguirre JD, Li YD, Brown J, Focht V, Kater L, Kempf G, Sandoval B, Schmitt S, Rutter JC, Galli P, Sandate CR, Cutler JA, Zou C, Donovan KA, ... ... Ebert BL, et al. UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability. Molecular Cell. PMID 37478846 DOI: 10.1016/j.molcel.2023.06.028 |
0.062 |
|
| 2005 |
Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, Sweet-Cordero A, Ebert BL, Mak RH, Ferrando AA, Downing JR, Jacks T, Horvitz HR, Golub TR. MicroRNA expression profiles classify human cancers. Nature. 435: 834-8. PMID 15944708 DOI: 10.1038/Nature03702 |
0.06 |
|
| 2023 |
Kozicka Z, Suchyta DJ, Focht V, Kempf G, Petzold G, Jentzsch M, Zou C, Di Genua C, Donovan KA, Coomar S, Cigler M, Mayor-Ruiz C, Schmid-Burgk JL, Häussinger D, Winter GE, ... ... Ebert BL, et al. Design principles for cyclin K molecular glue degraders. Nature Chemical Biology. PMID 37679459 DOI: 10.1038/s41589-023-01409-z |
0.06 |
|
| 2012 |
Mullally A, Ebert BL. Janus reveals another face: the biologic rationale for targeting Janus kinase 2 in lymphoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 4168-70. PMID 22965959 DOI: 10.1200/JCO.2012.44.0347 |
0.058 |
|
| 2018 |
Ebert BL, Krönke J. Inhibition of Casein Kinase 1 Alpha in Acute Myeloid Leukemia. The New England Journal of Medicine. 379: 1873-1874. PMID 30403945 DOI: 10.1056/NEJMcibr1811318 |
0.058 |
|
| 2010 |
Ebert BL. Preface. The biology and treatment of myelodysplastic syndrome. Hematology/Oncology Clinics of North America. 24: xiii-xvi. PMID 20359625 DOI: 10.1016/j.hoc.2010.02.014 |
0.056 |
|
| 2014 |
Okam MM, Shaykevich S, Ebert BL, Zaslavsky AM, Ayanian JZ. National trends in hospitalizations for sickle cell disease in the united states following the FDA approval of hydroxyurea, 1998-2008 Medical Care. 52: 612-618. PMID 24926708 DOI: 10.1097/Mlr.0000000000000143 |
0.05 |
|
| 2019 |
Sperling AS, Ebert BL. CHIPing away at breast cancer. Journal of the National Cancer Institute. PMID 31504659 DOI: 10.1093/jnci/djz158 |
0.043 |
|
| 2022 |
Richards M, Anderson M, Carter P, Ebert BL, Mossialos E. The impact of the COVID-19 pandemic on cancer care. Nature Cancer. 1: 565-567. PMID 35121972 DOI: 10.1038/s43018-020-0074-y |
0.042 |
|
| 2017 |
Sperling AS, Ebert BL. Prevalent premalignancy. Blood. 130: 695-696. PMID 28798057 DOI: 10.1182/blood-2017-05-786210 |
0.04 |
|
| 2013 |
Shah DI, Takahashi-Makise N, Cooney JD, Li L, Schultz IJ, Pierce EL, Narla A, Seguin A, Hattangadi SM, Medlock AE, Langer NB, Dailey TA, Hurst SN, Faccenda D, Wiwczar JM, ... ... Ebert BL, et al. Erratum: Corrigendum: Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts Nature. 496: 386-386. DOI: 10.1038/Nature12078 |
0.036 |
|
| 2016 |
Townsend EC, Murakami MA, Christodoulou A, Christie AL, Köster J, DeSouza TA, Morgan EA, Kallgren SP, Liu H, Wu SC, Plana O, Montero J, Stevenson KE, Rao P, Vadhi R, ... ... Ebert BL, et al. The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice. Cancer Cell. 30: 183. PMID 27479034 DOI: 10.1016/J.Ccell.2016.06.008 |
0.035 |
|
| 2019 |
Lin AE, Libby P, Ebert BL. A new opening on aortic stenosis: predicting prognosis with clonal haematopoiesis. European Heart Journal. PMID 31634387 DOI: 10.1093/eurheartj/ehz752 |
0.034 |
|
| 2022 |
Ebert BAR, Kirkelund GM. Effects of Chlorides and Sulphates on Heavy Metal Leaching from Mortar with Raw and Electrodialytically Treated MSWI Fly Ash. Waste and Biomass Valorization. 1-16. PMID 35035628 DOI: 10.1007/s12649-022-01686-0 |
0.033 |
|
| 2022 |
Rauch PJ, Ebert BL. Clonal hematopoiesis transcending species barriers. Blood. 140: 1748-1750. PMID 36264590 DOI: 10.1182/blood.2022017281 |
0.032 |
|
| 1998 |
Kühbacher T, Ebert B, Lochs H, Schreiber S. Antagonistic regulation of PMN apoptosis by G-CSF and IL-10/IL-4 Gastroenterology. 114: A1015. DOI: 10.1016/S0016-5085(98)84131-0 |
0.032 |
|
| 2018 |
Libby P, Molinaro R, Sellar RS, Ebert BL. Jak-ing Up the Plaque's Lipid Core…and Even More. Circulation Research. 123: 1180-1182. PMID 30571474 DOI: 10.1161/CIRCRESAHA.118.314074 |
0.03 |
|
| 2017 |
Ebert BL. Introduction to a review series on precision hematology. Blood. 130: 408-409. PMID 28600335 DOI: 10.1182/blood-2017-06-735753 |
0.03 |
|
| 2011 |
Narla A, Ebert BL. Translational medicine: ribosomopathies. Blood. 118: 4300-1. PMID 22021450 DOI: 10.1182/blood-2011-08-372250 |
0.024 |
|
| 2018 |
Ebert BL. Generations of physician-scientists. The Journal of Clinical Investigation. 128: 4208-4212. PMID 30272578 DOI: 10.1172/JCI124786 |
0.014 |
|
| 2021 |
Brand P, Ebert B, Esser A, Sharma R. Direct Exposure of Welders to Welding Fumes and Effect of Fume Extraction Systems Under Controlled Conditions. Journal of Occupational and Environmental Medicine. 63: 490-502. PMID 34048382 DOI: 10.1097/JOM.0000000000002167 |
0.012 |
|
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