| Year |
Citation |
Score |
| 2015 |
Schlie K, Westerback A, DeVorkin L, Hughson LR, Brandon JM, MacPherson S, Gadawski I, Townsend KN, Poon VI, Elrick MA, Côté HCF, Abraham N, Wherry EJ, Mizushima N, Lum JJ. Survival of effector CD8+ T cells during influenza infection is dependent on autophagy Journal of Immunology. 194: 4277-4286. PMID 25833396 DOI: 10.4049/Jimmunol.1402571 |
0.323 |
|
| 2007 |
Amaravadi RK, Yu D, Lum JJ, Bui T, Christophorou MA, Evan GI, Thomas-Tikhonenko A, Thompson CB. Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma. The Journal of Clinical Investigation. 117: 326-36. PMID 17235397 DOI: 10.1172/Jci28833 |
0.334 |
|
| 2005 |
Lum JJ, Bren G, McClure R, Badley AD. Elimination of senescent neutrophils by TNF-related apoptosis-inducing [corrected] ligand. Journal of Immunology (Baltimore, Md. : 1950). 175: 1232-8. PMID 16002727 DOI: 10.4049/Jimmunol.175.2.1232 |
0.562 |
|
| 2005 |
Lum JJ, Schnepple DJ, Badley AD. Acquired T-cell sensitivity to TRAIL mediated killing during HIV infection is regulated by CXCR4-gp120 interactions. Aids (London, England). 19: 1125-33. PMID 15990565 DOI: 10.1097/01.Aids.0000176212.16205.23 |
0.654 |
|
| 2005 |
Lum JJ, Bren G, McClure R, Badley AD. Elimination of senescent neutrophils by TNF-related apopotosis-inducing ligand The Journal of Immunology. 175: 3446.1-3446. DOI: 10.4049/jimmunol.175.5.3446 |
0.482 |
|
| 2004 |
Lum JJ, Schnepple DJ, Nie Z, Sanchez-Dardon J, Mbisa GL, Mihowich J, Hawley N, Narayan S, Kim JE, Lynch DH, Badley AD. Differential effects of interleukin-7 and interleukin-15 on NK cell anti-human immunodeficiency virus activity. Journal of Virology. 78: 6033-42. PMID 15141001 DOI: 10.1128/Jvi.78.11.6033-6042.2004 |
0.589 |
|
| 2004 |
Cooper CL, Phenix B, Mbisa G, Lum JJ, Parato K, Hawley N, Angel JB, Badley AD. Antiretroviral therapy influences cellular susceptibility to apoptosis in vivo. Frontiers in Bioscience : a Journal and Virtual Library. 9: 338-41. PMID 14766370 DOI: 10.2741/1230 |
0.673 |
|
| 2003 |
Lum JJ, Badley AD. Resistance to apoptosis: mechanism for the development of HIV reservoirs. Current Hiv Research. 1: 261-74. PMID 15046251 DOI: 10.2174/1570162033485203 |
0.692 |
|
| 2003 |
Badley AD, Roumier T, Lum JJ, Kroemer G. Mitochondrion-mediated apoptosis in HIV-1 infection. Trends in Pharmacological Sciences. 24: 298-305. PMID 12823956 DOI: 10.1016/S0165-6147(03)00125-1 |
0.668 |
|
| 2003 |
Lum JJ, Cohen OJ, Nie Z, Weaver JG, Gomez TS, Yao XJ, Lynch D, Pilon AA, Hawley N, Kim JE, Chen Z, Montpetit M, Sanchez-Dardon J, Cohen EA, Badley AD. Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis. The Journal of Clinical Investigation. 111: 1547-54. PMID 12750404 DOI: 10.1172/Jci16233 |
0.672 |
|
| 2002 |
Nie Z, Phenix BN, Lum JJ, Alam A, Lynch DH, Beckett B, Krammer PH, Sekaly RP, Badley AD. HIV-1 protease processes procaspase 8 to cause mitochondrial release of cytochrome c, caspase cleavage and nuclear fragmentation Cell Death and Differentiation. 9: 1172-1184. PMID 12404116 DOI: 10.1038/Sj.Cdd.4401094 |
0.69 |
|
| 2002 |
Pilon AA, Lum JJ, Sanchez-Dardon J, Phenix BN, Douglas R, Badley AD. Induction of apoptosis by a nonnucleoside human immunodeficiency virus type 1 reverse transcriptase inhibitor. Antimicrobial Agents and Chemotherapy. 46: 2687-91. PMID 12121958 DOI: 10.1128/Aac.46.8.2687-2691.2002 |
0.585 |
|
| 2001 |
Lum JJ, Pilon AA, Sanchez-Dardon J, Phenix BN, Kim JE, Mihowich J, Jamison K, Hawley-Foss N, Lynch DH, Badley AD. Induction of cell death in human immunodeficiency virus-infected macrophages and resting memory CD4 T cells by TRAIL/Apo2l. Journal of Virology. 75: 11128-36. PMID 11602752 DOI: 10.1128/Jvi.75.22.11128-11136.2001 |
0.688 |
|
| 2001 |
Phenix BN, Lum JJ, Nie Z, Sanchez-Dardon J, Badley AD. Antiapoptotic mechanism of HIV protease inhibitors: preventing mitochondrial transmembrane potential loss. Blood. 98: 1078-85. PMID 11493454 DOI: 10.1182/Blood.V98.4.1078 |
0.646 |
|
| 2001 |
Hawley-Foss N, Mbisa G, Lum JJ, Pilon AA, Angel JB, Garber G, Badley AD. Effect of cessation of highly active antiretroviral therapy during a discordant response: implications for scheduled therapeutic interruptions. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 33: 344-8. PMID 11438900 DOI: 10.1086/321902 |
0.536 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2017 |
DeVorkin L, Hattersley M, Kim P, Ries J, Spowart J, Anglesio MS, Levi SM, Huntsman DG, Amaravadi RK, Winkler JD, Tinker AV, Lum JJ. Autophagy Inhibition Enhances Sunitinib Efficacy in Clear Cell Ovarian Carcinoma. Molecular Cancer Research : McR. PMID 28184014 DOI: 10.1158/1541-7786.Mcr-16-0132 |
0.293 |
|
| 2005 |
Zweidler-McKay PA, Lum JJ, Thompson CB, Pear WS. A Critical Role for the Bcl-2 Pathway in Notch-Mediated B Cell Apoptosis, Where Growth Arrest Is Independent of the E2A, IL-3 and p21Waf1/p27Kip1 Pathways. Blood. 106: 237-237. DOI: 10.1182/Blood.V106.11.237.237 |
0.288 |
|
| 2015 |
Walter PB, Hohman L, Rokeby A, Lum J, Hagar R, Stewart M, Lavrisha L, Vichinsky E, Morris CR. The Effects of Glutamine Supplementation on Markers of Autophagy and Apoptosis in Peripheral Blood Mononuclear Cells from Patients with Sickle Cell Disease Blood. 126: 3412-3412. DOI: 10.1182/blood.V126.23.3412.3412 |
0.279 |
|
| 2016 |
DeVorkin L, Hattersley M, Kim P, Ries J, Spowart J, Anglesio MS, Levi SM, Huntsman DG, Amaravadi RK, Winkler JD, Tinker AV, Lum JJ. Autophagy Inhibition Enhances Sunitinib Efficacy in Clear Cell Ovarian Carcinoma. Molecular Cancer Research : McR. PMID 27927774 DOI: 10.1158/1541-7786.MCR-16-0132-T |
0.271 |
|
| 2019 |
DeVorkin L, Pavey N, Carleton G, Comber A, Ho C, Lim J, McNamara E, Huang H, Kim P, Zacharias LG, Mizushima N, Saitoh T, Akira S, Beckham W, Lorzadeh A, ... ... Lum JJ, et al. Autophagy Regulation of Metabolism Is Required for CD8 T Cell Anti-tumor Immunity. Cell Reports. 27: 502-513.e5. PMID 30970253 DOI: 10.1016/j.celrep.2019.03.037 |
0.245 |
|
| 2022 |
Walter PB, Hohman LS, Rokeby A, Lum JJ, Hagar R, Lavrisha L, Saulys A, Kuypers FA, Vichinsky E, Morris CR. The effects of glutamine supplementation on markers of apoptosis and autophagy in sickle cell disease peripheral blood mononuclear cells. Complementary Therapies in Medicine. 102856. PMID 35843474 DOI: 10.1016/j.ctim.2022.102856 |
0.245 |
|
| 2019 |
Carleton G, Lum JJ. Autophagy Metabolically Suppresses CD8 T Cell Antitumor Immunity. Autophagy. PMID 31170865 DOI: 10.1080/15548627.2019.1628545 |
0.241 |
|
| 2011 |
Ma XH, Piao S, Wang D, McAfee QW, Nathanson KL, Lum JJ, Li LZ, Amaravadi RK. Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3478-89. PMID 21325076 DOI: 10.1158/1078-0432.Ccr-10-2372 |
0.236 |
|
| 2005 |
Lum JJ, Bauer DE, Kong M, Harris MH, Li C, Lindsten T, Thompson CB. Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell. 120: 237-48. PMID 15680329 DOI: 10.1016/J.Cell.2004.11.046 |
0.233 |
|
| 2011 |
Schlie K, Spowart JE, Hughson LR, Townsend KN, Lum JJ. When Cells Suffocate: Autophagy in Cancer and Immune Cells under Low Oxygen. International Journal of Cell Biology. 2011: 470597. PMID 22190938 DOI: 10.1155/2011/470597 |
0.231 |
|
| 2019 |
Lum JJ. Exploring New Strategies to Monitor Autophagy and Related Cell Death Pathways Using Raman Spectroscopy Journal of Cancer Research and Therapeutic Oncology. 1: 1-5. DOI: 10.17303/JCRTO.2013.1.103 |
0.228 |
|
| 2005 |
Thompson CB, Bauer DE, Lum JJ, Hatzivassiliou G, Zong WX, Ditsworth D, Zhao F, Buzzai M, Lindsten T. How do cancer cells acquire the fuel needed to support cell growth? Cold Spring Harbor Symposia On Quantitative Biology. 70: 357-362. PMID 16869772 DOI: 10.1101/Sqb.2005.70.011 |
0.212 |
|
| 2022 |
Zhao T, Lum JJ. Methionine cycle-dependent regulation of T cells in cancer immunity. Frontiers in Oncology. 12: 969563. PMID 36033438 DOI: 10.3389/fonc.2022.969563 |
0.207 |
|
| 2012 |
Hughson LR, Poon VI, Spowart JE, Lum JJ. Implications of therapy-induced selective autophagy on tumor metabolism and survival. International Journal of Cell Biology. 2012: 872091. PMID 22550492 DOI: 10.1155/2012/872091 |
0.205 |
|
| 2015 |
Lebovitz CB, DeVorkin L, Bosc D, Rothe K, Singh J, Bally M, Jiang X, Young RN, Lum JJ, Gorski SM. Precision autophagy: Will the next wave of selective autophagy markers and specific autophagy inhibitors feed clinical pipelines? Autophagy. 11: 1949-52. PMID 26506897 DOI: 10.1080/15548627.2015.1078962 |
0.199 |
|
| 2008 |
DeBerardinis RJ, Lum JJ, Hatzivassiliou G, Thompson CB. The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metabolism. 7: 11-20. PMID 18177721 DOI: 10.1016/J.Cmet.2007.10.002 |
0.198 |
|
| 2021 |
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... Lum JJ, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280 |
0.197 |
|
| 2012 |
Spowart JE, Townsend KN, Huwait H, Eshragh S, West NR, Ries JN, Kalloger S, Anglesio M, Gorski SM, Watson PH, Gilks CB, Huntsman DG, Lum JJ. The autophagy protein LC3A correlates with hypoxia and is a prognostic marker of patient survival in clear cell ovarian cancer. The Journal of Pathology. 228: 437-47. PMID 22926683 DOI: 10.1002/path.4090 |
0.194 |
|
| 2007 |
Buzzai M, Jones RG, Amaravadi RK, Lum JJ, DeBerardinis RJ, Zhao F, Viollet B, Thompson CB. Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth. Cancer Research. 67: 6745-52. PMID 17638885 DOI: 10.1158/0008-5472.Can-06-4447 |
0.193 |
|
| 2018 |
MacPherson S, Kilgour M, Lum JJ. Understanding Lymphocyte Metabolism for Use in Cancer Immunotherapy. The Febs Journal. PMID 29611301 DOI: 10.1111/febs.14454 |
0.19 |
|
| 2024 |
McPhedran SJ, Carleton GA, Lum JJ. Metabolic engineering for optimized CAR-T cell therapy. Nature Metabolism. 6: 396-408. PMID 38388705 DOI: 10.1038/s42255-024-00976-2 |
0.188 |
|
| 2010 |
Zhao F, Mancuso A, Bui TV, Tong X, Gruber JJ, Swider CR, Sanchez PV, Lum JJ, Sayed N, Melo JV, Perl AE, Carroll M, Tuttle SW, Thompson CB. Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1alpha-induced metabolic reprograming. Oncogene. 29: 2962-72. PMID 20228846 DOI: 10.1038/Onc.2010.67 |
0.185 |
|
| 2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Lum JJ, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356 |
0.177 |
|
| 2023 |
McPhedran S, Choe J, MacPherson S, Kowalchuk G, Chan V, Kilgour MK, Lum JJ. Assessing the Immune Regulatory Role of Metabolites In Vitro. Methods in Molecular Biology (Clifton, N.J.). 2614: 109-120. PMID 36587122 DOI: 10.1007/978-1-0716-2914-7_8 |
0.176 |
|
| 2023 |
Guo N, Yang A, Farooq FB, Kalaria S, Moss E, DeVorkin L, Lesperance M, Bénard F, Wilson D, Tinker AV, Nathoo FS, Hamilton PT, Lum JJ. CD8 + T cell infiltration is associated with improved survival and negatively correlates with hypoxia in clear cell ovarian cancer. Scientific Reports. 13: 6530. PMID 37085560 DOI: 10.1038/s41598-023-30655-3 |
0.174 |
|
| 2022 |
MacPherson S, Keyes S, Kilgour MK, Smazynski J, Chan V, Sudderth J, Turcotte T, Devlieger A, Yu J, Huggler KS, Cantor JR, DeBerardinis RJ, Siatskas C, Lum JJ. Clinically relevant T cell expansion media activate distinct metabolic programs uncoupled from cellular function. Molecular Therapy. Methods & Clinical Development. 24: 380-393. PMID 35284590 DOI: 10.1016/j.omtm.2022.02.004 |
0.173 |
|
| 2014 |
Matthews Q, Isabelle M, Harder S, Brolo A, Lum J, Jirasek A. Sci-Fri AM: Mountain - 04: Label-free Raman spectroscopy of single tumour cells detects early radiation-induced glycogen synthesis associated with increased radiation resistance Medical Physics. 41: 23-24. DOI: 10.1118/1.4894943 |
0.172 |
|
| 2018 |
Poffenberger MC, Metcalfe-Roach A, Aguilar E, Chen J, Hsu BE, Wong AH, Johnson RM, Flynn B, Samborska B, Ma EH, Gravel SP, Tonelli L, Devorkin L, Kim P, Hall A, ... ... Lum JJ, et al. LKB1 deficiency in T cells promotes the development of gastrointestinal polyposis. Science (New York, N.Y.). 361: 406-411. PMID 30049881 DOI: 10.1126/science.aan3975 |
0.169 |
|
| 2021 |
Kilgour MK, MacPherson S, Zacharias LG, Ellis AE, Sheldon RD, Liu EY, Keyes S, Pauly B, Carleton G, Allard B, Smazynski J, Williams KS, Watson PH, Stagg J, Nelson BH, ... ... Lum JJ, et al. 1-Methylnicotinamide is an immune regulatory metabolite in human ovarian cancer. Science Advances. 7. PMID 33523930 DOI: 10.1126/sciadv.abe1174 |
0.168 |
|
| 2020 |
Seyfoori A, Barough MS, Amereh M, Jush BK, Lum JJ, Akbari M. Bioengineered tissue models for the development of dynamic immuno-associated tumor models and high-throughput immunotherapy cytotoxicity assays. Drug Discovery Today. PMID 33253917 DOI: 10.1016/j.drudis.2020.11.028 |
0.168 |
|
| 2015 |
Matthews Q, Isabelle M, Harder SJ, Smazynski J, Beckham W, Brolo AG, Jirasek A, Lum JJ. Radiation-Induced Glycogen Accumulation Detected by Single Cell Raman Spectroscopy Is Associated with Radioresistance that Can Be Reversed by Metformin. Plos One. 10: e0135356. PMID 26280348 DOI: 10.1371/Journal.Pone.0135356 |
0.164 |
|
| 2011 |
Matthews Q, Brolo AG, Lum J, Duan X, Jirasek A. Raman spectroscopy of single human tumour cells exposed to ionizing radiation in vitro Physics in Medicine and Biology. 56: 19-38. PMID 21119222 DOI: 10.1088/0031-9155/56/1/002 |
0.162 |
|
| 2012 |
Townsend KN, Hughson LRK, Schlie K, Poon VI, Westerback A, Lum JJ. Autophagy inhibition in cancer therapy: Metabolic considerations for antitumor immunity Immunological Reviews. 249: 176-194. PMID 22889222 DOI: 10.1111/j.1600-065X.2012.01141.x |
0.161 |
|
| 2011 |
Matthews Q, Jirasek A, Lum JJ, Brolo AG. Biochemical signatures of in vitro radiation response in human lung, breast and prostate tumour cells observed with Raman spectroscopy. Physics in Medicine and Biology. 56: 6839-55. PMID 21971286 DOI: 10.1088/0031-9155/56/21/006 |
0.156 |
|
| 2013 |
Jardon MA, Rothe K, Bortnik S, Vezenkov L, Jiang X, Young RN, Lum JJ, Gorski SM. Autophagy: from structure to metabolism to therapeutic regulation. Autophagy. 9: 2180-2. PMID 24201076 DOI: 10.4161/auto.26378 |
0.153 |
|
| 2005 |
Lum JJ, DeBerardinis RJ, Thompson CB. Autophagy in metazoans: cell survival in the land of plenty. Nature Reviews. Molecular Cell Biology. 6: 439-48. PMID 15928708 DOI: 10.1038/Nrm1660 |
0.149 |
|
| 2010 |
Matthews Q, Jirasek A, Lum J, Duan X, Brolo AG. Variability in Raman spectra of single human tumor cells cultured in vitro: correlation with cell cycle and culture confluency. Applied Spectroscopy. 64: 871-87. PMID 20719050 DOI: 10.1366/000370210792080966 |
0.145 |
|
| 2012 |
Gorski SM, Ries J, Lum JJ. Targeting autophagy: the Achilles' heel of cancer. Autophagy. 8: 1279-80. PMID 22836583 DOI: 10.4161/auto.20828 |
0.142 |
|
| 2022 |
McPhedran S, Lum JJ. Ubiquitinating the way to T cell metabolism. The Journal of Cell Biology. 221. PMID 35695892 DOI: 10.1083/jcb.202206006 |
0.139 |
|
| 2017 |
MacPherson S, Horkoff M, Gravel C, Hoffmann T, Zuber J, Lum JJ. STAT3 Regulation of Citrate Synthase Is Essential during the Initiation of Lymphocyte Cell Growth. Cell Reports. 19: 910-918. PMID 28467904 DOI: 10.1016/j.celrep.2017.04.012 |
0.137 |
|
| 2019 |
Tinker A, Lim P, Aquino-Parsons C, Hoskins P, Khalaf D, Lheureux S, Han K, Liu M, Lum JJ. Phase I (safety assessment) of durvalumab (MEDI4736) with focal sensitizing radiotherapy in platinum resistant ovarian, primary peritoneal or fallopian tube epithelial carcinoma. Journal of Clinical Oncology. 37: TPS5604-TPS5604. DOI: 10.1200/JCO.2019.37.15_SUPPL.TPS5604 |
0.137 |
|
| 2013 |
Townsend KN, Spowart JE, Huwait H, Eshragh S, West NR, Elrick MA, Kalloger SE, Anglesio M, Watson PH, Huntsman DG, Lum JJ. Markers of T cell infiltration and function associate with favorable outcome in vascularized high-grade serous ovarian carcinoma Plos One. 8. PMID 24376535 DOI: 10.1371/journal.pone.0082406 |
0.136 |
|
| 2012 |
Matthews Q, Jirasek A, Brolo A, Lum J. WE-C-BRA-09: Towards Treatment Monitoring of Tumour Radiation Response with Raman Spectroscopy Medical Physics. 39: 3948-3948. DOI: 10.1118/1.4736114 |
0.135 |
|
| 2022 |
Kilgour MK, MacPherson S, Zacharias LG, LeBlanc J, Babinszky S, Kowalchuk G, Parks S, Sheldon RD, Jones RG, DeBerardinis RJ, Hamilton PT, Watson PH, Lum JJ. Principles of reproducible metabolite profiling of enriched lymphocytes in tumors and ascites from human ovarian cancer. Nature Protocols. PMID 35986218 DOI: 10.1038/s41596-022-00729-z |
0.134 |
|
| 2010 |
Spowart J, Lum JJ. Opening a new DOR to autophagy. Embo Reports. 11: 4-5. PMID 20033084 DOI: 10.1038/embor.2009.265 |
0.133 |
|
| 2004 |
Bauer DE, Harris MH, Plas DR, Lum JJ, Hammerman PS, Rathmell JC, Riley JL, Thompson CB. Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1303-5. PMID 15180958 DOI: 10.1096/Fj.03-1001Fje |
0.133 |
|
| 2021 |
Milligan K, Deng X, Shreeves P, Ali-Adeeb R, Matthews Q, Brolo A, Lum JJ, Andrews JL, Jirasek A. Raman spectroscopy and group and basis-restricted non negative matrix factorisation identifies radiation induced metabolic changes in human cancer cells. Scientific Reports. 11: 3853. PMID 33594122 DOI: 10.1038/s41598-021-83343-5 |
0.133 |
|
| 2014 |
Neilson D, MacPherson S, Townsend KN, Lum JJ. Tumor vascularity in ovarian cancer: T cells need breathing room. Oncoimmunology. 3: e28272. PMID 25050200 DOI: 10.4161/onci.28272 |
0.13 |
|
| 2015 |
Harder SJ, Matthews Q, Isabelle M, Brolo AG, Lum JJ, Jirasek A. A Raman spectroscopic study of cell response to clinical doses of ionizing radiation. Applied Spectroscopy. 69: 193-204. PMID 25588147 DOI: 10.1366/14-07561 |
0.128 |
|
| 2014 |
Neilson D, MacPherson S, Townsend KN, Lum JJ. Tumor vascularity in ovarian cancer: T cells need breathing room Oncoimmunology. 3. DOI: 10.4161/onci.28272 |
0.125 |
|
| 2007 |
Lum JJ, Bui T, Gruber M, Gordan JD, DeBerardinis RJ, Covello KL, Simon MC, Thompson CB. The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis. Genes & Development. 21: 1037-49. PMID 17437992 DOI: 10.1101/Gad.1529107 |
0.123 |
|
| 2006 |
Deberardinis RJ, Lum JJ, Thompson CB. Phosphatidylinositol 3-kinase-dependent modulation of carnitine palmitoyltransferase 1A expression regulates lipid metabolism during hematopoietic cell growth. The Journal of Biological Chemistry. 281: 37372-80. PMID 17030509 DOI: 10.1074/Jbc.M608372200 |
0.121 |
|
| 2017 |
Joe MB, Lum JJ, Watson PH, Tonseth RP, McGhie JP, Truong PT. Radiation generates an abscopal response and complete resolution of metastatic squamous cell carcinoma of the anal canal: a case report. Journal of Gastrointestinal Oncology. 8: E84-E89. PMID 29299375 DOI: 10.21037/jgo.2017.06.15 |
0.12 |
|
| 2020 |
Deng X, Ali-Adeeb R, Andrews J, Shreeves P, Lum J, Brolo A, Jirasek A. EXPRESS: Monitoring Ionizing Radiation-Induced Cellular Responses Using Raman Spectroscopy, Non-Negative Matrix Factorization, and Non-Negative Least Squares. Applied Spectroscopy. 3702820906221. PMID 32098482 DOI: 10.1177/0003702820906221 |
0.119 |
|
| 2024 |
Fuentes AM, Milligan K, Wiebe M, Narayan A, Lum JJ, Brolo AG, Andrews JL, Jirasek A. Stratification of tumour cell radiation response and metabolic signatures visualization with Raman spectroscopy and explainable convolutional neural network. The Analyst. PMID 38312026 DOI: 10.1039/d3an01797d |
0.119 |
|
| 2023 |
MacPherson S, Duncan KD, Goodlett DR, Lum JJ. Strategies for uncovering stable isotope tracing patterns between cell populations. Current Opinion in Biotechnology. 83: 102991. PMID 37619527 DOI: 10.1016/j.copbio.2023.102991 |
0.118 |
|
| 2009 |
Gruber JJ, Zatechka DS, Sabin LR, Yong J, Lum JJ, Kong M, Zong WX, Zhang Z, Lau CK, Rawlings J, Cherry S, Ihle JN, Dreyfuss G, Thompson CB. Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation. Cell. 138: 328-39. PMID 19632182 DOI: 10.1016/J.Cell.2009.04.046 |
0.116 |
|
| 2011 |
Matthews Q, Jirasek A, Brolo A, Lum J. TH-C-220-12: Biochemical Radiation Response of Irradiated Human Tumour Cells Observed via Raman Spectroscopy Medical Physics. 38: 3865-3865. DOI: 10.1118/1.3613555 |
0.115 |
|
| 2014 |
Kumar A, Gilks CB, Clarke B, Aquino-Parsons C, McAlpine JN, Lum JJ, Tinker A. Adjuvant radiation for patients (pts) with high-grade serous ovarian cancer (HGSC) and T-cell infiltration. Journal of Clinical Oncology. 32: 5543-5543. DOI: 10.1200/jco.2014.32.15_suppl.5543 |
0.115 |
|
| 2014 |
Johnson LD, Nesslinger NJ, Blood PA, Chima N, Richier LR, Ludgate C, Pai HH, Lim JT, Nelson BH, Vlachaki MT, Lum JJ. Tumor-associated autoantibodies correlate with poor outcome in prostate cancer patients treated with androgen deprivation and external beam radiation therapy. Oncoimmunology. 3: e29243. PMID 25114831 DOI: 10.4161/Onci.29243 |
0.114 |
|
| 2016 |
Harder SJ, Isabelle M, DeVorkin L, Smazynski J, Beckham W, Brolo A, Lum J, Jirasek A. Sci-Thur PM - Colourful Interactions: Highlights 03: Radiation induced glycogen accumulation in non-small cell lung cancer xenografts detected using Raman spectroscopy Medical Physics. 43: 4931-4931. DOI: 10.1118/1.4961763 |
0.113 |
|
| 2022 |
Deng X, Milligan K, Brolo A, Lum JJ, Andrews JL, Jirasek A. Radiation treatment response and hypoxia biomarkers revealed by machine learning assisted Raman spectroscopy in tumour cells and xenograft tissues. The Analyst. PMID 36217911 DOI: 10.1039/d2an01222g |
0.112 |
|
| 2021 |
Tessier-Cloutier B, Twa DD, Marzban M, Kalina J, Chun HE, Pavey N, Tanweer Z, Katz RL, Lum JJ, Salina D. The presence of tumour-infiltrating neutrophils is an independent adverse prognostic feature in clear cell renal cell carcinoma. The Journal of Pathology. Clinical Research. PMID 33665979 DOI: 10.1002/cjp2.204 |
0.109 |
|
| 2018 |
Sobral-Filho RG, DeVorkin L, Macpherson S, Jirasek A, Lum JJ, Brolo AG. Ex Vivo Detection of Circulating Tumor Cells from Whole Blood by Direct Nanoparticle Visualization. Acs Nano. PMID 29401387 DOI: 10.1021/Acsnano.7B08813 |
0.109 |
|
| 2017 |
Kalina JL, Neilson DS, Lin YY, Hamilton PT, Comber AP, Loy EMH, Sahinalp SC, Collins CC, Hach F, Lum JJ. Mutational Analysis of Gene Fusions Predicts Novel MHC Class I-Restricted T cell Epitopes & Immune Signatures in a Subset of Prostate Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28954787 DOI: 10.1158/1078-0432.Ccr-17-0618 |
0.108 |
|
| 2016 |
Harder SJ, Isabelle M, DeVorkin L, Smazynski J, Beckham W, Brolo AG, Lum JJ, Jirasek A. Raman spectroscopy identifies radiation response in human non-small cell lung cancer xenografts. Scientific Reports. 6: 21006. PMID 26883914 DOI: 10.1038/Srep21006 |
0.107 |
|
| 2019 |
Van Nest SJ, Nicholson LM, Pavey N, Hindi MN, Brolo AG, Jirasek A, Lum JJ. Raman spectroscopy detects metabolic signatures of radiation response and hypoxic fluctuations in non-small cell lung cancer. Bmc Cancer. 19: 474. PMID 31109312 DOI: 10.1186/S12885-019-5686-1 |
0.106 |
|
| 2023 |
Stringer E, Lum JJ, Livergant J, Kushniruk AW. Decision Aids for Patients With Head and Neck Cancer: Qualitative Elicitation of Design Recommendations From Patient End Users. Jmir Human Factors. 10: e43551. PMID 37276012 DOI: 10.2196/43551 |
0.088 |
|
| 2017 |
Kalina JL, Neilson DS, Comber AP, Rauw JM, Alexander AS, Vergidis J, Lum JJ. Immune Modulation by Androgen Deprivation and Radiation Therapy: Implications for Prostate Cancer Immunotherapy. Cancers. 9. PMID 28134800 DOI: 10.3390/cancers9020013 |
0.088 |
|
| 2018 |
Van Nest SJ, Nicholson LM, DeVorkin L, Brolo AG, Lum JJ, Jirasek A. Raman Spectroscopic Signatures Reveal Distinct Biochemical and Temporal Changes in Irradiated Human Breast Adenocarcinoma Xenografts. Radiation Research. PMID 29474157 DOI: 10.1667/Rr15003.1 |
0.085 |
|
| 2018 |
Meksiarun P, Aoki PHB, Van Nest SJ, Sobral-Filho RG, Lum JJ, Brolo AG, Jirasek A. Breast cancer subtype specific biochemical responses to radiation. The Analyst. PMID 30004539 DOI: 10.1039/C8An00345A |
0.084 |
|
| 2024 |
Simunic M, Joshi JT, Merkens H, Colpo N, Kuo HT, Lum JJ, Bénard F. PSMA imaging as a non-invasive tool to monitor inducible gene expression in vivo. Ejnmmi Research. 14: 3. PMID 38177950 DOI: 10.1186/s13550-023-01063-5 |
0.082 |
|
| 2019 |
Milosevich N, McFarlane J, Gignac MC, Li J, Brown TM, Wilson CR, Devorkin L, Croft CS, Hof R, Paci I, Lum JJ, Hof F. Pan-specific and partially selective dye-labeled peptidic inhibitors of the polycomb paralog proteins. Bioorganic & Medicinal Chemistry. 115176. PMID 31753799 DOI: 10.1016/J.Bmc.2019.115176 |
0.082 |
|
| 2021 |
Deng X, Milligan K, Ali-Adeeb R, Shreeves P, Brolo A, Lum JJ, Andrews JL, Jirasek A. Group and Basis Restricted Non-Negative Matrix Factorization and Random Forest for Molecular Histotype Classification and Raman Biomarker Monitoring in Breast Cancer. Applied Spectroscopy. 37028211035398. PMID 34355582 DOI: 10.1177/00037028211035398 |
0.076 |
|
| 2022 |
Milligan K, Van Nest SJ, Deng X, Ali-Adeeb R, Shreeves P, Punch S, Costie N, Pavey N, Crook JM, Berman DM, Brolo AG, Lum JJ, Andrews JL, Jirasek A. Raman spectroscopy and supervised learning as a potential tool to identify HDR-brachytherapy-induced biochemical profiles of prostate cancer. Journal of Biophotonics. e202200121. PMID 35908273 DOI: 10.1002/jbio.202200121 |
0.073 |
|
| 2022 |
Milligan K, Deng X, Ali-Adeeb R, Shreeves P, Punch S, Costie N, Crook JM, Brolo AG, Lum JJ, Andrews JL, Jirasek A. Prediction of disease progression indicators in prostate cancer patients receiving HDR-brachytherapy using Raman spectroscopy and semi-supervised learning: a pilot study. Scientific Reports. 12: 15104. PMID 36068275 DOI: 10.1038/s41598-022-19446-4 |
0.063 |
|
| 2024 |
Wiebe M, Milligan K, Brewer J, Fuentes AM, Ali-Adeeb R, Brolo AG, Lum JJ, Andrews JL, Haston C, Jirasek A. Metabolic profiling of murine radiation-induced lung injury with Raman spectroscopy and comparative machine learning. The Analyst. PMID 38619825 DOI: 10.1039/d4an00152d |
0.063 |
|
| 2023 |
Fuentes AM, Narayan A, Milligan K, Lum JJ, Brolo AG, Andrews JL, Jirasek A. Raman spectroscopy and convolutional neural networks for monitoring biochemical radiation response in breast tumour xenografts. Scientific Reports. 13: 1530. PMID 36707535 DOI: 10.1038/s41598-023-28479-2 |
0.061 |
|
| 2013 |
Razavi M, Johnson LD, Lum JJ, Kruppa G, Anderson NL, Pearson TW. Quantification of a proteotypic peptide from protein C inhibitor by liquid chromatography-free SISCAPA-MALDI mass spectrometry: application to identification of recurrence of prostate cancer. Clinical Chemistry. 59: 1514-22. PMID 23857672 DOI: 10.1373/Clinchem.2012.199786 |
0.061 |
|
| 2014 |
Walter P, Otto S, Sharf K, Riddett E, Huey Tan H, Fournier R, Zhang F, Choy F, Linhardt R, Lum J, Harmatz P. Investigation of Pharmacological Chaperones and Gluthathione in the Enhancement of NAcetylgalactosamine- 6-Sulfate Sulfatase (GALNS) in the Treatment of Mucopolysaccharidosis IVA Free Radical Biology and Medicine. 76: S95-S96. DOI: 10.1016/J.Freeradbiomed.2014.10.330 |
0.06 |
|
| 2019 |
Vrbik I, Van Nest SJ, Meksiarun P, Loeppky J, Brolo A, Lum JJ, Jirasek A. Haralick texture feature analysis for quantifying radiation response heterogeneity in murine models observed using Raman spectroscopic mapping. Plos One. 14: e0212225. PMID 30768630 DOI: 10.1371/Journal.Pone.0212225 |
0.058 |
|
| 2024 |
Duncan KD, Pětrošová H, Lum JJ, Goodlett DR. Mass spectrometry imaging methods for visualizing tumor heterogeneity. Current Opinion in Biotechnology. 86: 103068. PMID 38310648 DOI: 10.1016/j.copbio.2024.103068 |
0.057 |
|
| 2017 |
Joe MB, Lum JJ, Watson PH, Tonseth RP, McGhie JP, Truong PT. CT images showing multiple liver metastases pre-treatment on left hand panel and resolution of liver disease on right hand panel 4 weeks after pelvic radiation therapy and chemotherapy Asvide. 4: 514-514. DOI: 10.21037/asvide.2017.514 |
0.053 |
|
| 2019 |
Elisia I, Cho B, Hay M, Li MY, Hofs E, Lam V, Dyer RA, Lum J, Krystal G. The Effect of Diet and Exercise on Tobacco Carcinogen-induced Lung Cancer. Carcinogenesis. PMID 30874285 DOI: 10.1093/Carcin/Bgz060 |
0.048 |
|
| 2023 |
Milligan K, Scarrott K, Andrews JL, Brolo AG, Lum JJ, Jirasek A. Reconstruction of Raman Spectra of Biochemical Mixtures Using Group and Basis Restricted Non-Negative Matrix Factorization. Applied Spectroscopy. 37028231169971. PMID 37097829 DOI: 10.1177/00037028231169971 |
0.041 |
|
| 2022 |
Stringer E, Lum JJ, Macpherson N. Intermittent Fasting in Cancer: a Role in Survivorship? Current Nutrition Reports. PMID 35639262 DOI: 10.1007/s13668-022-00425-0 |
0.031 |
|
| 2012 |
Blood P, Johnson L, Beckham W, Russell G, Pai H, Lim J, Richier L, Nelson B, Vlachaki M, Lum J. PO-46: CTLA-4 Blockade with Androgen Deprivation and Radiotherapy for the Treatment of Prostate Cancer Radiotherapy and Oncology. 104: 35. DOI: 10.1016/S0167-8140(15)34600-4 |
0.027 |
|
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