| Year |
Citation |
Score |
| 2020 |
Sha Z, Fishovitz J, Wang S, Chilakala S, Xu Y, Lee I. A Selective Fluorogenic Peptide Substrate for the Human Mitochondrial ATP-Dependent Protease Complex ClpXP. Chembiochem : a European Journal of Chemical Biology. PMID 32180333 DOI: 10.1002/Cbic.202000030 |
0.496 |
|
| 2020 |
Sha Z, Chilakala S, Crabill G, Cheng I, Xu Y, Fishovitz J, Lee I. A Proteolytic Site-Directed Affinity Label to Inhibit the Human ATP-Dependent Protease Caseinolytic Complex XP. Chembiochem : a European Journal of Chemical Biology. PMID 32180302 DOI: 10.1002/Cbic.202000031 |
0.564 |
|
| 2017 |
Fishovitz J, Sha Z, Chilakala S, Cheng I, Xu Y, Lee I. Utilization of Mechanistic Enzymology to Evaluate the Significance of ADP Binding to Human Lon Protease. Frontiers in Molecular Biosciences. 4: 47. PMID 28744459 DOI: 10.3389/Fmolb.2017.00047 |
0.511 |
|
| 2016 |
Lee I, Berdis AJ. Physiological enzymology: The next frontier in understanding protein structure and function at the cellular level. Biochimica Et Biophysica Acta. 1864: 65-9. PMID 26277093 DOI: 10.1016/J.Bbapap.2015.07.011 |
0.355 |
|
| 2013 |
Golden J, Motea E, Zhang X, Choi JS, Feng Y, Xu Y, Lee I, Berdis AJ. Development and characterization of a non-natural nucleoside that displays anticancer activity against solid tumors. Acs Chemical Biology. 8: 2452-65. PMID 23992753 DOI: 10.1021/Cb400350H |
0.744 |
|
| 2013 |
Mikita N, Cheng I, Fishovitz J, Huang J, Lee I. Processive degradation of unstructured protein by Escherichia coli Lon occurs via the slow, sequential delivery of multiple scissile sites followed by rapid and synchronized peptide bond cleavage events. Biochemistry. 52: 5629-44. PMID 23822859 DOI: 10.1021/Bi4008319 |
0.51 |
|
| 2013 |
Motea EA, Lee I, Berdis AJ. Insights into the roles of desolvation and π-electron interactions during DNA polymerization. Chembiochem : a European Journal of Chemical Biology. 14: 489-98. PMID 23404822 DOI: 10.1002/Cbic.201200649 |
0.782 |
|
| 2013 |
Devadoss B, Lee I, Berdis AJ. Spectroscopic analysis of polymerization and exonuclease proofreading by a high-fidelity DNA polymerase during translesion DNA synthesis. Biochimica Et Biophysica Acta. 1834: 34-45. PMID 22959853 DOI: 10.1016/J.Bbapap.2012.08.019 |
0.479 |
|
| 2012 |
Motea EA, Lee I, Berdis AJ. A non-natural nucleoside with combined therapeutic and diagnostic activities against leukemia. Acs Chemical Biology. 7: 988-98. PMID 22390204 DOI: 10.1021/Cb300038F |
0.749 |
|
| 2012 |
Cheng I, Mikita N, Fishovitz J, Frase H, Wintrode P, Lee I. Identification of a region in the N-terminus of Escherichia coli Lon that affects ATPase, substrate translocation and proteolytic activity. Journal of Molecular Biology. 418: 208-25. PMID 22387465 DOI: 10.1016/J.Jmb.2012.02.039 |
0.772 |
|
| 2012 |
Craig S, Gao L, Lee I, Gray T, Berdis AJ. Gold-containing indoles as anticancer agents that potentiate the cytotoxic effects of ionizing radiation. Journal of Medicinal Chemistry. 55: 2437-51. PMID 22289037 DOI: 10.1021/Jm2005942 |
0.331 |
|
| 2012 |
Venkatesh S, Lee J, Singh K, Lee I, Suzuki CK. Multitasking in the mitochondrion by the ATP-dependent Lon protease. Biochimica Et Biophysica Acta. 1823: 56-66. PMID 22119779 DOI: 10.1016/J.Bbamcr.2011.11.003 |
0.461 |
|
| 2012 |
Motea EA, Lee I, Berdis AJ. Development of a 'clickable' non-natural nucleotide to visualize the replication of non-instructional DNA lesions. Nucleic Acids Research. 40: 2357-67. PMID 22086959 DOI: 10.1093/Nar/Gkr980 |
0.755 |
|
| 2011 |
Fishovitz J, Li M, Frase H, Hudak J, Craig S, Ko K, Berdis AJ, Suzuki CK, Lee I. Active-site-directed chemical tools for profiling mitochondrial Lon protease. Acs Chemical Biology. 6: 781-8. PMID 21520912 DOI: 10.1021/Cb100408W |
0.744 |
|
| 2011 |
Ernberg K, Zhong B, Ko K, Miller L, Nguyen YH, Sayre LM, Guss JM, Lee I. Structural and enzyme activity studies demonstrate that aryl substituted 2,3-butadienamine analogs inactivate Arthrobacter globiformis amine oxidase (AGAO) by chemical derivatization of the 2,4,5-trihydroxyphenylalanine quinone (TPQ) cofactor. Biochimica Et Biophysica Acta. 1814: 638-46. PMID 21215824 DOI: 10.1016/J.Bbapap.2010.12.016 |
0.472 |
|
| 2011 |
Motea EA, Lee I, Berdis AJ. Quantifying the energetic contributions of desolvation and π-electron density during translesion DNA synthesis. Nucleic Acids Research. 39: 1623-37. PMID 20952399 DOI: 10.1093/Nar/Gkq925 |
0.76 |
|
| 2010 |
Knott K, Fishovitz J, Thorpe SB, Lee I, Santos WL. N-Terminal peptidic boronic acids selectively inhibit human ClpXP. Organic & Biomolecular Chemistry. 8: 3451-6. PMID 20523950 DOI: 10.1039/C004247A |
0.398 |
|
| 2010 |
Zhang X, Motea E, Lee I, Berdis AJ. Replication of a universal nucleobase provides unique insight into the role of entropy during DNA polymerization and pyrophosphorolysis. Biochemistry. 49: 3009-23. PMID 20187654 DOI: 10.1021/Bi901523Y |
0.75 |
|
| 2010 |
Thomas J, Fishovitz J, Lee I. Utilization of positional isotope exchange experiments to evaluate reversibility of ATP hydrolysis catalyzed by Escherichia coli Lon protease. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 88: 119-28. PMID 20130685 DOI: 10.1139/o09-117 |
0.301 |
|
| 2010 |
Lee I, Berdis AJ. Non-natural nucleotides as probes for the mechanism and fidelity of DNA polymerases. Biochimica Et Biophysica Acta. 1804: 1064-80. PMID 19733263 DOI: 10.1016/J.Bbapap.2009.08.023 |
0.429 |
|
| 2009 |
Patterson-Ward J, Tedesco J, Hudak J, Fishovitz J, Becker J, Frase H, McNamara K, Lee I. Utilization of synthetic peptides to evaluate the importance of substrate interaction at the proteolytic site of Escherichia coli Lon protease. Biochimica Et Biophysica Acta. 1794: 1355-63. PMID 19285157 DOI: 10.1016/J.Bbapap.2009.02.015 |
0.776 |
|
| 2008 |
Sheriff A, Motea E, Lee I, Berdis AJ. Mechanism and dynamics of translesion DNA synthesis catalyzed by the Escherichia coli Klenow fragment. Biochemistry. 47: 8527-37. PMID 18652487 DOI: 10.1021/Bi800324R |
0.766 |
|
| 2008 |
Lee I, Suzuki CK. Functional mechanics of the ATP-dependent Lon protease- lessons from endogenous protein and synthetic peptide substrates. Biochimica Et Biophysica Acta. 1784: 727-35. PMID 18359303 DOI: 10.1016/J.Bbapap.2008.02.010 |
0.434 |
|
| 2008 |
Licht S, Lee I. Resolving individual steps in the operation of ATP-dependent proteolytic molecular machines: from conformational changes to substrate translocation and processivity. Biochemistry. 47: 3595-605. PMID 18311925 DOI: 10.1021/Bi800025G |
0.424 |
|
| 2007 |
Devadoss B, Lee I, Berdis AJ. Enhancing the "A-rule" of translesion DNA synthesis: promutagenic DNA synthesis using modified nucleoside triphosphates. Biochemistry. 46: 13752-61. PMID 17983244 DOI: 10.1021/Bi701328H |
0.425 |
|
| 2007 |
Patterson-Ward J, Huang J, Lee I. Detection and characterization of two ATP-dependent conformational changes in proteolytically inactive Escherichia coli Lon mutants by stopped flow kinetic techniques. Biochemistry. 46: 13593-605. PMID 17975895 DOI: 10.1021/Bi701649B |
0.55 |
|
| 2007 |
Vineyard D, Zhang X, Donnelly A, Lee I, Berdis AJ. Optimization of non-natural nucleotides for selective incorporation opposite damaged DNA. Organic & Biomolecular Chemistry. 5: 3623-30. PMID 17971991 DOI: 10.1039/B712480E |
0.793 |
|
| 2007 |
Frase H, Lee I. Peptidyl boronates inhibit Salmonella enterica serovar Typhimurium Lon protease by a competitive ATP-dependent mechanism. Biochemistry. 46: 6647-57. PMID 17497890 DOI: 10.1021/Bi7002789 |
0.777 |
|
| 2007 |
Devadoss B, Lee I, Berdis AJ. Is a thymine dimer replicated via a transient abasic site intermediate? A comparative study using non-natural nucleotides. Biochemistry. 46: 4486-98. PMID 17378586 DOI: 10.1021/Bi602438T |
0.498 |
|
| 2006 |
Lee I, Berdis AJ, Suzuki CK. Recent developments in the mechanistic enzymology of the ATP-dependent Lon protease from Escherichia coli: highlights from kinetic studies. Molecular Biosystems. 2: 477-83. PMID 17216028 DOI: 10.1039/B609936J |
0.53 |
|
| 2006 |
Lee I, Berdis A. Fluorescent analysis of translesion DNA synthesis by using a novel, non-natural nucleotide analogue. Chembiochem : a European Journal of Chemical Biology. 7: 1990-7. PMID 17091513 DOI: 10.1002/Cbic.200600128 |
0.458 |
|
| 2006 |
Zhang X, Donnelly A, Lee I, Berdis AJ. Rational attempts to optimize non-natural nucleotides for selective incorporation opposite an abasic site. Biochemistry. 45: 13293-303. PMID 17073450 DOI: 10.1021/Bi060418V |
0.478 |
|
| 2006 |
Vineyard D, Zhang X, Lee I. Transient kinetic experiments demonstrate the existence of a unique catalytic enzyme form in the peptide-stimulated ATPase mechanism of Escherichia coli Lon protease. Biochemistry. 45: 11432-43. PMID 16981703 DOI: 10.1021/Bi060809+ |
0.825 |
|
| 2006 |
Frase H, Hudak J, Lee I. Identification of the proteasome inhibitor MG262 as a potent ATP-dependent inhibitor of the Salmonella enterica serovar Typhimurium Lon protease. Biochemistry. 45: 8264-74. PMID 16819825 DOI: 10.1021/Bi060542E |
0.748 |
|
| 2006 |
Vineyard D, Patterson-Ward J, Lee I. Single-turnover kinetic experiments confirm the existence of high- and low-affinity ATPase sites in Escherichia coli Lon protease. Biochemistry. 45: 4602-10. PMID 16584195 DOI: 10.1021/Bi052377T |
0.821 |
|
| 2006 |
Zhang X, Lee I, Zhou X, Berdis AJ. Hydrophobicity, shape, and pi-electron contributions during translesion DNA synthesis. Journal of the American Chemical Society. 128: 143-9. PMID 16390141 DOI: 10.1021/Ja0546830 |
0.512 |
|
| 2005 |
Zhang X, Lee I, Berdis AJ. A potential chemotherapeutic strategy for the selective inhibition of promutagenic DNA synthesis by nonnatural nucleotides. Biochemistry. 44: 13111-21. PMID 16185079 DOI: 10.1021/Bi050584N |
0.462 |
|
| 2005 |
Zhang X, Lee I, Berdis AJ. The use of nonnatural nucleotides to probe the contributions of shape complementarity and pi-electron surface area during DNA polymerization. Biochemistry. 44: 13101-10. PMID 16185078 DOI: 10.1021/Bi050585F |
0.462 |
|
| 2005 |
Vineyard D, Patterson-Ward J, Berdis AJ, Lee I. Monitoring the timing of ATP hydrolysis with activation of peptide cleavage in Escherichia coli Lon by transient kinetics. Biochemistry. 44: 1671-82. PMID 15683251 DOI: 10.1021/Bi048618Z |
0.819 |
|
| 2004 |
Zhang X, Lee I, Berdis AJ. Evaluating the contributions of desolvation and base-stacking during translesion DNA synthesis. Organic & Biomolecular Chemistry. 2: 1703-11. PMID 15188037 DOI: 10.1039/B401732C |
0.479 |
|
| 2004 |
Patterson J, Vineyard D, Thomas-Wohlever J, Behshad R, Burke M, Lee I. Correlation of an adenine-specific conformational change with the ATP-dependent peptidase activity of Escherichia coli Lon. Biochemistry. 43: 7432-42. PMID 15182186 DOI: 10.1021/Bi036165C |
0.75 |
|
| 2004 |
Liu T, Lu B, Lee I, Ondrovicová G, Kutejová E, Suzuki CK. DNA and RNA binding by the mitochondrial lon protease is regulated by nucleotide and protein substrate. The Journal of Biological Chemistry. 279: 13902-10. PMID 14739292 DOI: 10.1074/Jbc.M309642200 |
0.526 |
|
| 2003 |
Lu B, Liu T, Crosby JA, Thomas-Wohlever J, Lee I, Suzuki CK. The ATP-dependent Lon protease of Mus musculus is a DNA-binding protein that is functionally conserved between yeast and mammals. Gene. 306: 45-55. PMID 12657466 DOI: 10.1016/S0378-1119(03)00403-7 |
0.782 |
|
| 2002 |
Thomas-Wohlever J, Lee I. Kinetic characterization of the peptidase activity of Escherichia coli Lon reveals the mechanistic similarities in ATP-dependent hydrolysis of peptide and protein substrates. Biochemistry. 41: 9418-25. PMID 12135363 DOI: 10.1021/Bi0255470 |
0.783 |
|
| 2001 |
Lee I, Berdis AJ. Adenosine triphosphate-dependent degradation of a fluorescent lambda N substrate mimic by Lon protease. Analytical Biochemistry. 291: 74-83. PMID 11262158 DOI: 10.1006/Abio.2001.4988 |
0.565 |
|
| 1998 |
Berdis AJ, Lee I, Coward JK, Stephens C, Wright R, Shapiro L, Benkovic SJ. A cell cycle-regulated adenine DNA methyltransferase from Caulobacter crescentus processively methylates GANTC sites on hemimethylated DNA. Proceedings of the National Academy of Sciences of the United States of America. 95: 2874-9. PMID 9501183 DOI: 10.1073/Pnas.95.6.2874 |
0.448 |
|
| 1995 |
Lee I, Stewart JD, Zhong WY, Benkovic SJ. A Chemiluminescent Immunoassay for the Identification of Functional Single-Chain Antibodies Analytical Biochemistry. 230: 62-67. PMID 8585631 DOI: 10.1006/Abio.1995.1438 |
0.334 |
|
| 1995 |
Stewart JD, Lee I, Posner BA, Benkovic SJ. Expression of properly folded catalytic antibodies in Escherichia coli Methods in Enzymology. 249: 507-519. PMID 7791625 DOI: 10.1016/0076-6879(95)49047-7 |
0.326 |
|
| 1993 |
Posner B, Lee I, Itoh T, Pyati J, Graff R, Thorton GB, La Polla R, Benkovic SJ. A revised strategy for cloning antibody gene fragments in bacteria. Gene. 128: 111-7. PMID 8508951 DOI: 10.1016/0378-1119(93)90161-U |
0.33 |
|
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