| Year |
Citation |
Score |
| 2022 |
Berdis A. Nucleobase-modified nucleosides and nucleotides: Applications in biochemistry, synthetic biology, and drug discovery. Frontiers in Chemistry. 10: 1051525. PMID 36531317 DOI: 10.3389/fchem.2022.1051525 |
0.419 |
|
| 2019 |
Choi JS, Berdis A. An Artificial Nucleoside That Simultaneously Detects and Combats Drug Resistance to Doxorubicin. European Journal of Haematology. PMID 31729766 DOI: 10.1111/Ejh.13347 |
0.544 |
|
| 2019 |
Choi JS, Berdis A. Artificial Nucleosides as Diagnostic Probes to Measure Translesion DNA Synthesis. Methods in Molecular Biology (Clifton, N.J.). 1973: 237-249. PMID 31016706 DOI: 10.1007/978-1-4939-9216-4_15 |
0.598 |
|
| 2019 |
Hernandez-Sanchez W, Huang W, Plucinsky B, Garcia-Vazquez N, Robinson NJ, Schiemann WP, Berdis AJ, Skordalakes E, Taylor DJ. A non-natural nucleotide uses a specific pocket to selectively inhibit telomerase activity. Plos Biology. 17: e3000204. PMID 30951520 DOI: 10.1371/Journal.Pbio.3000204 |
0.363 |
|
| 2018 |
Choi JS, Berdis A. Combating resistance to DNA damaging agents. Oncoscience. 5: 134-136. PMID 30035165 DOI: 10.18632/oncoscience.423 |
0.367 |
|
| 2018 |
Zeng X, Hernandez-Sanchez W, Xu M, Whited TL, Baus D, Zhang J, Berdis AJ, Taylor DJ. Administration of a Nucleoside Analog Promotes Cancer Cell Death in a Telomerase-Dependent Manner. Cell Reports. 23: 3031-3041. PMID 29874588 DOI: 10.1016/J.Celrep.2018.05.020 |
0.437 |
|
| 2018 |
Maity A, Deligonul N, Berdis AJ, Gray TG. 6-Mercaptopurine Nucleoside Complexes of Gold(I): Synthesis and Cytotoxicity Postdoc Journal. DOI: 10.14304/Surya.Jpr.V6N1.2 |
0.301 |
|
| 2017 |
Choi JS, Kim CS, Berdis A. Inhibition of translesion DNA synthesis as a novel therapeutic strategy to treat brain cancer. Cancer Research. PMID 29259011 DOI: 10.1158/0008-5472.Can-17-2464 |
0.5 |
|
| 2017 |
Berdis AJ. Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer. Frontiers in Molecular Biosciences. 4: 78. PMID 29201867 DOI: 10.3389/Fmolb.2017.00078 |
0.587 |
|
| 2017 |
Dasari A, Deodhar T, Berdis AJ. A comparative analysis of translesion DNA synthesis catalyzed by a high fidelity DNA polymerase. Journal of Molecular Biology. PMID 28601494 DOI: 10.1016/J.Jmb.2017.06.003 |
0.62 |
|
| 2017 |
Choi JS, Kim S, Motea E, Berdis A. Inhibiting translesion DNA synthesis as an approach to combat drug resistance to DNA damaging agents. Oncotarget. PMID 28489578 DOI: 10.18632/Oncotarget.17254 |
0.572 |
|
| 2016 |
Misko TA, Wijerathna SR, Radivoyevitch T, Berdis AJ, Ahmad MF, Harris ME, Dealwis CG. Inhibition of yeast ribonucleotide reductase by Sml1 depends on the allosteric state of the enzyme. Febs Letters. PMID 27155231 DOI: 10.1002/1873-3468.12207 |
0.362 |
|
| 2016 |
Lee I, Berdis AJ. Physiological enzymology: The next frontier in understanding protein structure and function at the cellular level. Biochimica Et Biophysica Acta. 1864: 65-9. PMID 26277093 DOI: 10.1016/J.Bbapap.2015.07.011 |
0.31 |
|
| 2016 |
Choi JS, Berdis AJ. Visualizing nucleic acid metabolism using non-natural nucleosides and nucleotide analogs. Biochimica Et Biophysica Acta. 1864: 165-76. PMID 26004088 DOI: 10.1016/J.Bbapap.2015.05.010 |
0.511 |
|
| 2016 |
Hernandez-Sanchez WM, Baus D, Berdis AJ, Taylor DJ. Abstract 2714: Inhibition of human telomerase by new purine analogs Cancer Research. 76: 2714-2714. DOI: 10.1158/1538-7445.Am2016-2714 |
0.362 |
|
| 2015 |
Choi JS, Dasari A, Hu P, Benkovic SJ, Berdis AJ. The use of modified and non-natural nucleotides provide unique insights into pro-mutagenic replication catalyzed by polymerase eta. Nucleic Acids Research. PMID 26717984 DOI: 10.1093/Nar/Gkv1509 |
0.594 |
|
| 2015 |
Scotland MK, Heltzel JM, Kath JE, Choi JS, Berdis AJ, Loparo JJ, Sutton MD. A Genetic Selection for dinB Mutants Reveals an Interaction between DNA Polymerase IV and the Replicative Polymerase That Is Required for Translesion Synthesis. Plos Genetics. 11: e1005507. PMID 26352807 DOI: 10.1371/Journal.Pgen.1005507 |
0.505 |
|
| 2015 |
Choi JS, Maity A, Gray T, Berdis AJ. A metal-containing nucleoside that possesses both therapeutic and diagnostic activity against cancer. The Journal of Biological Chemistry. 290: 9714-26. PMID 25713072 DOI: 10.1074/Jbc.M114.620294 |
0.309 |
|
| 2013 |
Golden J, Motea E, Zhang X, Choi JS, Feng Y, Xu Y, Lee I, Berdis AJ. Development and characterization of a non-natural nucleoside that displays anticancer activity against solid tumors. Acs Chemical Biology. 8: 2452-65. PMID 23992753 DOI: 10.1021/Cb400350H |
0.459 |
|
| 2013 |
Motea EA, Lee I, Berdis AJ. Insights into the roles of desolvation and π-electron interactions during DNA polymerization. Chembiochem : a European Journal of Chemical Biology. 14: 489-98. PMID 23404822 DOI: 10.1002/Cbic.201200649 |
0.542 |
|
| 2013 |
Devadoss B, Lee I, Berdis AJ. Spectroscopic analysis of polymerization and exonuclease proofreading by a high-fidelity DNA polymerase during translesion DNA synthesis. Biochimica Et Biophysica Acta. 1834: 34-45. PMID 22959853 DOI: 10.1016/J.Bbapap.2012.08.019 |
0.627 |
|
| 2012 |
Ahmad MF, Wan Q, Jha S, Motea E, Berdis A, Dealwis C. Evaluating the therapeutic potential of a non-natural nucleotide that inhibits human ribonucleotide reductase. Molecular Cancer Therapeutics. 11: 2077-86. PMID 22933704 DOI: 10.1158/1535-7163.Mct-12-0199 |
0.353 |
|
| 2012 |
Motea EA, Lee I, Berdis AJ. A non-natural nucleoside with combined therapeutic and diagnostic activities against leukemia. Acs Chemical Biology. 7: 988-98. PMID 22390204 DOI: 10.1021/Cb300038F |
0.452 |
|
| 2012 |
Craig S, Gao L, Lee I, Gray T, Berdis AJ. Gold-containing indoles as anticancer agents that potentiate the cytotoxic effects of ionizing radiation. Journal of Medicinal Chemistry. 55: 2437-51. PMID 22289037 DOI: 10.1021/Jm2005942 |
0.373 |
|
| 2012 |
Motea EA, Lee I, Berdis AJ. Development of a 'clickable' non-natural nucleotide to visualize the replication of non-instructional DNA lesions. Nucleic Acids Research. 40: 2357-67. PMID 22086959 DOI: 10.1093/Nar/Gkr980 |
0.578 |
|
| 2011 |
Chavarria D, Ramos-Serrano A, Hirao I, Berdis AJ. Exploring the roles of nucleobase desolvation and shape complementarity during the misreplication of O(6)-methylguanine. Journal of Molecular Biology. 412: 325-39. PMID 21819995 DOI: 10.1016/J.Jmb.2011.07.011 |
0.499 |
|
| 2011 |
Krishnamurthy N, Ngam CR, Berdis AJ, Montano MM. The exonuclease activity of hPMC2 is required for transcriptional regulation of the QR gene and repair of estrogen-induced abasic sites. Oncogene. 30: 4731-9. PMID 21602889 DOI: 10.1038/Onc.2011.186 |
0.454 |
|
| 2011 |
Sanders LH, Devadoss B, Raja GV, O'Connor J, Su S, Wozniak DJ, Hassett DJ, Berdis AJ, Sutton MD. Epistatic roles for Pseudomonas aeruginosa MutS and DinB (DNA Pol IV) in coping with reactive oxygen species-induced DNA damage. Plos One. 6: e18824. PMID 21533111 DOI: 10.1371/Journal.Pone.0018824 |
0.477 |
|
| 2011 |
Fishovitz J, Li M, Frase H, Hudak J, Craig S, Ko K, Berdis AJ, Suzuki CK, Lee I. Active-site-directed chemical tools for profiling mitochondrial Lon protease. Acs Chemical Biology. 6: 781-8. PMID 21520912 DOI: 10.1021/Cb100408W |
0.307 |
|
| 2011 |
Motea EA, Lee I, Berdis AJ. Quantifying the energetic contributions of desolvation and π-electron density during translesion DNA synthesis. Nucleic Acids Research. 39: 1623-37. PMID 20952399 DOI: 10.1093/Nar/Gkq925 |
0.485 |
|
| 2010 |
Berdis AJ. DNA polymerases: Perfect enzymes for an imperfect world. Biochimica Et Biophysica Acta. 1804: 1029-31. PMID 20188219 DOI: 10.1016/J.Bbapap.2010.02.005 |
0.571 |
|
| 2010 |
Zhang X, Motea E, Lee I, Berdis AJ. Replication of a universal nucleobase provides unique insight into the role of entropy during DNA polymerization and pyrophosphorolysis. Biochemistry. 49: 3009-23. PMID 20187654 DOI: 10.1021/Bi901523Y |
0.516 |
|
| 2010 |
Eng K, Scouten-Ponticelli SK, Sutton M, Berdis A. Selective inhibition of DNA replicase assembly by a non-natural nucleotide: exploiting the structural diversity of ATP-binding sites. Acs Chemical Biology. 5: 183-94. PMID 19994907 DOI: 10.1021/Cb900218C |
0.585 |
|
| 2010 |
Lee I, Berdis AJ. Non-natural nucleotides as probes for the mechanism and fidelity of DNA polymerases. Biochimica Et Biophysica Acta. 1804: 1064-80. PMID 19733263 DOI: 10.1016/J.Bbapap.2009.08.023 |
0.558 |
|
| 2010 |
Motea EA, Berdis AJ. Terminal deoxynucleotidyl transferase: the story of a misguided DNA polymerase. Biochimica Et Biophysica Acta. 1804: 1151-66. PMID 19596089 DOI: 10.1016/J.Bbapap.2009.06.030 |
0.613 |
|
| 2009 |
Berdis AJ. Mechanisms of DNA polymerases. Chemical Reviews. 109: 2862-79. PMID 19489544 DOI: 10.1021/Cr800530B |
0.558 |
|
| 2008 |
Sheriff A, Motea E, Lee I, Berdis AJ. Mechanism and dynamics of translesion DNA synthesis catalyzed by the Escherichia coli Klenow fragment. Biochemistry. 47: 8527-37. PMID 18652487 DOI: 10.1021/Bi800324R |
0.59 |
|
| 2008 |
Berdis AJ. DNA polymerases as therapeutic targets. Biochemistry. 47: 8253-60. PMID 18642851 DOI: 10.1021/Bi801179F |
0.525 |
|
| 2007 |
Devadoss B, Lee I, Berdis AJ. Enhancing the "A-rule" of translesion DNA synthesis: promutagenic DNA synthesis using modified nucleoside triphosphates. Biochemistry. 46: 13752-61. PMID 17983244 DOI: 10.1021/Bi701328H |
0.612 |
|
| 2007 |
Vineyard D, Zhang X, Donnelly A, Lee I, Berdis AJ. Optimization of non-natural nucleotides for selective incorporation opposite damaged DNA. Organic & Biomolecular Chemistry. 5: 3623-30. PMID 17971991 DOI: 10.1039/B712480E |
0.605 |
|
| 2007 |
Berdis AJ, McCutcheon D. The use of non-natural nucleotides to probe template-independent DNA synthesis. Chembiochem : a European Journal of Chemical Biology. 8: 1399-408. PMID 17607682 DOI: 10.1002/Cbic.200700096 |
0.631 |
|
| 2007 |
Devadoss B, Lee I, Berdis AJ. Is a thymine dimer replicated via a transient abasic site intermediate? A comparative study using non-natural nucleotides. Biochemistry. 46: 4486-98. PMID 17378586 DOI: 10.1021/Bi602438T |
0.592 |
|
| 2007 |
Devadoss B, Berdis A. Non-Natural Nucleotide Analogs as Probes of DNA Polymerase Activity Current Chemical Biology. 1: 241-264. DOI: 10.2174/2212796810701030241 |
0.553 |
|
| 2006 |
Lee I, Berdis AJ, Suzuki CK. Recent developments in the mechanistic enzymology of the ATP-dependent Lon protease from Escherichia coli: highlights from kinetic studies. Molecular Biosystems. 2: 477-83. PMID 17216028 DOI: 10.1039/B609936J |
0.372 |
|
| 2006 |
Lee I, Berdis A. Fluorescent analysis of translesion DNA synthesis by using a novel, non-natural nucleotide analogue. Chembiochem : a European Journal of Chemical Biology. 7: 1990-7. PMID 17091513 DOI: 10.1002/Cbic.200600128 |
0.601 |
|
| 2006 |
Zhang X, Donnelly A, Lee I, Berdis AJ. Rational attempts to optimize non-natural nucleotides for selective incorporation opposite an abasic site. Biochemistry. 45: 13293-303. PMID 17073450 DOI: 10.1021/Bi060418V |
0.632 |
|
| 2006 |
Zhuang Z, Berdis AJ, Benkovic SJ. An alternative clamp loading pathway via the T4 clamp loader gp44/62-DNA complex. Biochemistry. 45: 7976-89. PMID 16800623 DOI: 10.1021/Bi0601205 |
0.455 |
|
| 2006 |
Jao SC, English Ospina SM, Berdis AJ, Starke DW, Post CB, Mieyal JJ. Computational and mutational analysis of human glutaredoxin (thioltransferase): probing the molecular basis of the low pKa of cysteine 22 and its role in catalysis. Biochemistry. 45: 4785-96. PMID 16605247 DOI: 10.1021/Bi0516327 |
0.335 |
|
| 2006 |
Zhang X, Lee I, Zhou X, Berdis AJ. Hydrophobicity, shape, and pi-electron contributions during translesion DNA synthesis. Journal of the American Chemical Society. 128: 143-9. PMID 16390141 DOI: 10.1021/Ja0546830 |
0.559 |
|
| 2005 |
Zhang X, Lee I, Berdis AJ. A potential chemotherapeutic strategy for the selective inhibition of promutagenic DNA synthesis by nonnatural nucleotides. Biochemistry. 44: 13111-21. PMID 16185079 DOI: 10.1021/Bi050584N |
0.632 |
|
| 2005 |
Zhang X, Lee I, Berdis AJ. The use of nonnatural nucleotides to probe the contributions of shape complementarity and pi-electron surface area during DNA polymerization. Biochemistry. 44: 13101-10. PMID 16185078 DOI: 10.1021/Bi050585F |
0.588 |
|
| 2005 |
Ignatov ME, Berdis AJ, Le Grice SF, Barkley MD. Attenuation of DNA replication by HIV-1 reverse transcriptase near the central termination sequence. Biochemistry. 44: 5346-56. PMID 15807528 DOI: 10.1021/Bi048000P |
0.546 |
|
| 2004 |
Zhuang Z, Spiering MM, Berdis AJ, Trakselis MA, Benkovic SJ. 'Screw-cap' clamp loader proteins that thread. Nature Structural & Molecular Biology. 11: 580-1. PMID 15221017 DOI: 10.1038/Nsmb0704-580 |
0.492 |
|
| 2004 |
Zhang X, Lee I, Berdis AJ. Evaluating the contributions of desolvation and base-stacking during translesion DNA synthesis. Organic & Biomolecular Chemistry. 2: 1703-11. PMID 15188037 DOI: 10.1039/B401732C |
0.621 |
|
| 2004 |
Reineks EZ, Berdis AJ. Evaluating the contribution of base stacking during translesion DNA replication. Biochemistry. 43: 393-404. PMID 14717593 DOI: 10.1021/Bi034948S |
0.751 |
|
| 2003 |
Reineks EZ, Berdis AJ. Evaluating the effects of enhanced processivity and metal ions on translesion DNA replication catalyzed by the bacteriophage T4 DNA polymerase. Journal of Molecular Biology. 328: 1027-45. PMID 12729739 DOI: 10.1016/S0022-2836(03)00370-X |
0.752 |
|
| 2003 |
Trakselis MA, Berdis AJ, Benkovic SJ. Examination of the role of the clamp-loader and ATP hydrolysis in the formation of the bacteriophage T4 polymerase holoenzyme. Journal of Molecular Biology. 326: 435-51. PMID 12559912 DOI: 10.1016/S0022-2836(02)01330-X |
0.572 |
|
| 2002 |
Hays H, Berdis AJ. Manganese substantially alters the dynamics of translesion DNA synthesis. Biochemistry. 41: 4771-8. PMID 11939771 DOI: 10.1021/Bi0120648 |
0.497 |
|
| 2001 |
Berdis AJ, Stetor SR, LeGrice SFJ, Barkley MD. Molecular mechanism of sequence-specific termination of lentiviral replication Biochemistry. 40: 12140-12149. PMID 11580289 DOI: 10.1021/Bi010354I |
0.532 |
|
| 2001 |
Berdis AJ. Dynamics of translesion DNA synthesis catalyzed by the bacteriophage T4 exonuclease-deficient DNA polymerase. Biochemistry. 40: 7180-91. PMID 11401565 DOI: 10.1021/Bi0101594 |
0.53 |
|
| 2001 |
Lee I, Berdis AJ. Adenosine triphosphate-dependent degradation of a fluorescent lambda N substrate mimic by Lon protease. Analytical Biochemistry. 291: 74-83. PMID 11262158 DOI: 10.1006/Abio.2001.4988 |
0.342 |
|
| 1998 |
Berdis AJ, Benkovic SJ. Simultaneous formation of functional leading and lagging strand holoenzyme complexes on a small, defined DNA substrate. Proceedings of the National Academy of Sciences of the United States of America. 95: 11128-33. PMID 9736701 DOI: 10.1073/Pnas.95.19.11128 |
0.603 |
|
| 1998 |
Sexton DJ, Berdis AJ, Benkovic SJ. Assembly and disassembly of DNA polymerase holoenzyme. Current Opinion in Chemical Biology. 1: 316-22. PMID 9667868 DOI: 10.1016/S1367-5931(97)80068-3 |
0.478 |
|
| 1998 |
Sexton DJ, Kaboord BF, Berdis AJ, Carver TE, Benkovic SJ. Dissecting the order of bacteriophage T4 DNA polymerase holoenzyme assembly. Biochemistry. 37: 7749-56. PMID 9601035 DOI: 10.1021/Bi980088H |
0.576 |
|
| 1998 |
Berdis AJ, Lee I, Coward JK, Stephens C, Wright R, Shapiro L, Benkovic SJ. A cell cycle-regulated adenine DNA methyltransferase from Caulobacter crescentus processively methylates GANTC sites on hemimethylated DNA. Proceedings of the National Academy of Sciences of the United States of America. 95: 2874-9. PMID 9501183 DOI: 10.1073/Pnas.95.6.2874 |
0.542 |
|
| 1997 |
Berdis AJ, Benkovic SJ. Mechanism of bacteriophage T4 DNA holoenzyme assembly: the 44/62 protein acts as a molecular motor. Biochemistry. 36: 2733-43. PMID 9062100 DOI: 10.1021/Bi962139L |
0.447 |
|
| 1996 |
Berdis AJ, Soumillion P, Benkovic SJ. The carboxyl terminus of the bacteriophage T4 DNA polymerase is required for holoenzyme complex formation. Proceedings of the National Academy of Sciences of the United States of America. 93: 12822-7. PMID 8917503 DOI: 10.1073/Pnas.93.23.12822 |
0.459 |
|
| 1996 |
Sexton DJ, Carver TE, Berdis AJ, Benkovic SJ. Protein-protein and protein-DNA interactions at the bacteriophage T4 DNA replication fork. Characterization of a fluorescently labeled DNA polymerase sliding clamp. The Journal of Biological Chemistry. 271: 28045-51. PMID 8910415 DOI: 10.1074/Jbc.271.45.28045 |
0.527 |
|
| 1996 |
Berdis AJ, Benkovic SJ. Role of adenosine 5'-triphosphate hydrolysis in the assembly of the bacteriophage T4 DNA replication holoenzyme complex. Biochemistry. 35: 9253-65. PMID 8703931 DOI: 10.1021/Bi952569W |
0.488 |
|
| 1994 |
Stewart JD, Krebs JF, Siuzdak G, Berdis AJ, Smithrud DB, Benkovic SJ. Dissection of an antibody-catalyzed reaction Proceedings of the National Academy of Sciences of the United States of America. 91: 7404-7409. PMID 8052597 DOI: 10.1073/Pnas.91.16.7404 |
0.304 |
|
| 1993 |
Berdis AJ, Cook PF. Overall kinetic mechanism of 6-phosphogluconate dehydrogenase from Candida utilis. Biochemistry. 32: 2036-40. PMID 8448161 DOI: 10.1021/Bi00059A021 |
0.31 |
|
| 1993 |
Berdis AJ, Cook PF. The 2'-phosphate of NADP is critical for optimum productive binding to 6-phosphogluconate dehydrogenase from Candida utilis. Archives of Biochemistry and Biophysics. 305: 551-8. PMID 8373193 DOI: 10.1006/Abbi.1993.1460 |
0.321 |
|
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