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Yan Xu - Publications

Affiliations: 
Anesthesiology University of Pittsburgh, Pittsburgh, PA, United States 
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Year Citation  Score
2023 Bondarenko V, Chen Q, Singewald K, Haloi N, Tillman TS, Howard RJ, Lindahl E, Xu Y, Tang P. Structural Elucidation of Ivermectin Binding to α7nAChR and the Induced Channel Desensitization. Acs Chemical Neuroscience. PMID 36821490 DOI: 10.1021/acschemneuro.2c00783  0.721
2023 Tillman TS, Chen Q, Bondarenko V, Coleman JA, Xu Y, Tang P. SARS-CoV-2 Spike Protein Downregulates Cell Surface α7nAChR through a Helical Motif in the Spike Neck. Acs Chemical Neuroscience. PMID 36745901 DOI: 10.1021/acschemneuro.2c00610  0.619
2022 Bondarenko V, Wells MM, Chen Q, Tillman TS, Singewald K, Lawless MJ, Caporoso J, Brandon N, Coleman JA, Saxena S, Lindahl E, Xu Y, Tang P. Structures of highly flexible intracellular domain of human α7 nicotinic acetylcholine receptor. Nature Communications. 13: 793. PMID 35145092 DOI: 10.1038/s41467-022-28400-x  0.689
2021 Xiao J, Bondarenko V, Wang Y, Suma A, Wells M, Chen Q, Tillman T, Luo Y, Yu B, Dailey WP, Eckenhoff R, Tang P, Carnevale V, Klein ML, Xu Y. Regulation and drug modulation of a voltage-gated sodium channel: Pivotal role of the S4-S5 linker in activation and slow inactivation. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34260401 DOI: 10.1073/pnas.2102285118  0.69
2020 Yao L, Wells M, Wu X, Xu Y, Zhang L, Xiong W. Membrane cholesterol dependence of cannabinoid modulation of glycine receptor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32608538 DOI: 10.1096/Fj.201903093R  0.34
2020 Caporoso J, Moses M, Koper K, Tillman TS, Jiang L, Brandon N, Chen Q, Tang P, Xu Y. A Thermal Place Preference Test for Discovery of Neuropathic Pain Drugs. Acs Chemical Neuroscience. PMID 32191433 DOI: 10.1021/Acschemneuro.0C00013  0.602
2020 Tillman TS, Choi Z, Xu Y, Tang P. Functional Tolerance to Cysteine Mutations in Human α7 Nicotinic Acetylcholine Receptors. Acs Chemical Neuroscience. PMID 31951367 DOI: 10.1021/Acschemneuro.9B00647  0.694
2019 Bondarenko V, Wells MM, Chen Q, Singewald KC, Saxena S, Xu Y, Tang P. F Paramagnetic Relaxation-Based NMR for Quaternary Structural Restraints of Ion Channels. Acs Chemical Biology. PMID 31525026 DOI: 10.1021/Acschembio.9B00692  0.683
2019 Wells MM, Bondarenko V, Tillman TS, Singewald K, Lawless MJ, Caporoso J, Brandon N, Chen C, Kinde MN, Saxena S, Xu Y, Lindahl E, Tang P. Integrative Structure Determination of α7nAChR Intracellular Domain Biophysical Journal. 116: 394a. DOI: 10.1016/J.Bpj.2018.11.2133  0.771
2019 Tillman TS, Xu Y, Tang P. Functional Tolerance of Human α7 Nicotinic Acetylcholine Receptor to Cysteine Labeling Biophysical Journal. 116: 393a. DOI: 10.1016/J.Bpj.2018.11.2128  0.646
2019 Bondarenko V, Wells M, Chen Q, Tillman T, Xu Y, Tang P. Long Distance NMR Restraints for the Flexible α7nAChR Intracellular Domain Biophysical Journal. 116: 393a. DOI: 10.1016/J.Bpj.2018.11.2127  0.651
2018 Chen Q, Wells MM, Arjunan P, Tillman TS, Cohen AE, Xu Y, Tang P. Structural basis of neurosteroid anesthetic action on GABA receptors. Nature Communications. 9: 3972. PMID 30266951 DOI: 10.1038/S41467-018-06361-4  0.742
2018 Wang Y, Yang E, Wells MM, Bondarenko V, Woll K, Carnevale V, Granata D, Klein ML, Eckenhoff RG, Dailey WP, Covarrubias M, Tang P, Xu Y. Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites. The Journal of General Physiology. PMID 30018039 DOI: 10.1085/Jgp.201811993  0.736
2018 Zhang C, Brandon NR, Koper K, Tang P, Xu Y, Dou H. Invasion of Peripheral Immune Cells into Brain Parenchyma after Cardiac Arrest and Resuscitation. Aging and Disease. 9: 412-425. PMID 29896429 DOI: 10.14336/Ad.2017.0926  0.611
2018 Bondarenko V, Wells M, Xu Y, Tang P. Solution NMR Studies of Anesthetic Interactions with Ion Channels. Methods in Enzymology. 603: 49-66. PMID 29673534 DOI: 10.1016/Bs.Mie.2018.01.018  0.72
2018 Chen Q, Xu Y, Tang P. X-Ray Crystallographic Studies for Revealing Binding Sites of General Anesthetics in Pentameric Ligand-Gated Ion Channels. Methods in Enzymology. 603: 21-47. PMID 29673527 DOI: 10.1016/Bs.Mie.2018.01.017  0.708
2018 Chen Q, Wells MM, Arjunan P, Tillman TS, Adell D, Cohen AE, Xu Y, Tang P. Structures and Functions of ELIC-GABAAR Chimeras Biophysical Journal. 114: 299a. DOI: 10.1016/J.Bpj.2017.11.1705  0.645
2017 Ion BF, Wells MM, Chen Q, Xu Y, Tang P. Ketamine Inhibition of the Pentameric Ligand-Gated Ion Channel GLIC. Biophysical Journal. 113: 605-612. PMID 28793215 DOI: 10.1016/J.Bpj.2017.06.041  0.731
2017 Wells MM, Reinert N, Tang P, Xu Y. Structure-Based Discovery of Novel Glycinergic Modulators Biophysical Journal. 112: 556a. DOI: 10.1016/J.Bpj.2016.11.2998  0.724
2017 Ion BF, Wells MM, Xu Y, Tang P. Ketamine Inhibition of Pentameric Ligand-Gated Ion Channels - Insights from Molecular Dynamics Simulations Biophysical Journal. 112: 554a. DOI: 10.1016/J.Bpj.2016.11.2989  0.706
2017 Wang Y, Wells MM, Dailey W, Eckenhoff R, Tang P, Xu Y. Multiple Mechanisms of Propofol Inhibition of the Voltage-Gated Sodium Channel Nachbac: A 19 F NMR Investigation Biophysical Journal. 112: 18a. DOI: 10.1016/J.Bpj.2016.11.133  0.731
2016 Chen Q, Wells MM, Tillman TS, Kinde MN, Cohen A, Xu Y, Tang P. Structural Basis of Alcohol Inhibition of the Pentameric Ligand-Gated Ion Channel ELIC. Structure (London, England : 1993). PMID 27916519 DOI: 10.1016/J.Str.2016.11.007  0.804
2016 Kinde MN, Bondarenko V, Granata D, Bu W, Grasty KC, Loll PJ, Carnevale V, Klein ML, Eckenhoff RG, Tang P, Xu Y. Fluorine-19 NMR and computational quantification of isoflurane binding to the voltage-gated sodium channel NaChBac. Proceedings of the National Academy of Sciences of the United States of America. PMID 27856739 DOI: 10.1073/Pnas.1609939113  0.8
2016 Jia LJ, Tang P, Brandon NR, Luo Y, Yu B, Xu Y. Effects of Propofol General Anesthesia on Olfactory Relearning. Scientific Reports. 6: 33538. PMID 27628686 DOI: 10.1038/Srep33538  0.62
2016 Tillman TS, Alvarez FJ, Reinert NJ, Liu C, Wang D, Xu Y, Xiao K, Zhang P, Tang P. Functional Human α7 Nicotinic Acetylcholine Receptor (nAChR) Generated from E. coli. The Journal of Biological Chemistry. PMID 27385587 DOI: 10.1074/Jbc.M116.729970  0.685
2016 Stollings LM, Jia LJ, Tang P, Dou H, Lu B, Xu Y. Immune Modulation by Volatile Anesthetics. Anesthesiology. PMID 27286478 DOI: 10.1097/Aln.0000000000001195  0.611
2016 Kinde MN, Bu W, Chen Q, Xu Y, Eckenhoff RG, Tang P. Common Anesthetic-binding Site for Inhibition of Pentameric Ligand-gated Ion Channels. Anesthesiology. PMID 26756520 DOI: 10.1097/Aln.0000000000001005  0.813
2016 Wells MM, Maxwell A, Xu Y, Tang P. Novel Modulators of Glycine Receptors Biophysical Journal. 110: 543a. DOI: 10.1016/J.Bpj.2015.11.2905  0.705
2015 Zhou DW, Mowrey DD, Tang P, Xu Y. Percolation Model of Sensory Transmission and Loss of Consciousness Under General Anesthesia. Physical Review Letters. 115: 108103. PMID 26382705 DOI: 10.1103/Physrevlett.115.108103  0.732
2015 Chen Q, Kinde MN, Arjunan P, Wells MM, Cohen AE, Xu Y, Tang P. Direct Pore Binding as a Mechanism for Isoflurane Inhibition of the Pentameric Ligand-gated Ion Channel ELIC. Scientific Reports. 5: 13833. PMID 26346220 DOI: 10.1038/Srep13833  0.821
2015 Kinde MN, Chen Q, Lawless MJ, Mowrey DD, Xu J, Saxena S, Xu Y, Tang P. Conformational Changes Underlying Desensitization of the Pentameric Ligand-Gated Ion Channel ELIC. Structure (London, England : 1993). 23: 995-1004. PMID 25960405 DOI: 10.1016/J.Str.2015.03.017  0.806
2015 Chong Y, Kleinhammes A, Tang P, Xu Y, Wu Y. Dominant Alcohol-Protein Interaction via Hydration-Enabled Enthalpy-Driven Binding Mechanism. The Journal of Physical Chemistry. B. 119: 5367-75. PMID 25856773 DOI: 10.1021/Acs.Jpcb.5B00378  0.673
2015 Wells MM, Tillman TS, Mowrey DD, Sun T, Xu Y, Tang P. Ensemble-based virtual screening for cannabinoid-like potentiators of the human glycine receptor α1 for the treatment of pain. Journal of Medicinal Chemistry. 58: 2958-66. PMID 25790278 DOI: 10.1021/Jm501873P  0.685
2015 Mowrey DD, Kinde MN, Xu Y, Tang P. Atomistic insights into human Cys-loop receptors by solution NMR. Biochimica Et Biophysica Acta. 1848: 307-14. PMID 24680782 DOI: 10.1016/J.Bbamem.2014.03.014  0.816
2015 Chen Q, Kinde MN, Cohen AE, Tang P, Xu Y. Crystal View of Anesthetics and Alcohols Bound in the Pore of ELIC Biophysical Journal. 108: 55a. DOI: 10.1016/J.Bpj.2014.11.333  0.802
2015 Kinde MN, Bu W, Seyoum E, Chen Q, Wells MM, Mowrey DD, Eckenhoff RG, Xu Y, Tang P. A Shared Binding Site for Propofol and Thiopental in ELIC Biophysical Journal. 108: 55a. DOI: 10.1016/J.Bpj.2014.11.332  0.798
2015 Wells MM, Mowrey DD, Seyoum E, Sun T, Xu Y, Tang P. Positive Modulators of Glycine Receptors with Analgesic Potential Identified by Virtual Screening Biophysical Journal. 108: 357a. DOI: 10.1016/J.Bpj.2014.11.1955  0.682
2014 Tillman TS, Seyoum E, Mowrey DD, Xu Y, Tang P. ELIC-α7 Nicotinic acetylcholine receptor (α7nAChR) chimeras reveal a prominent role of the extracellular-transmembrane domain interface in allosteric modulation. The Journal of Biological Chemistry. 289: 13851-7. PMID 24695730 DOI: 10.1074/Jbc.M113.524611  0.704
2014 Samuelsson AR, Brandon NR, Tang P, Xu Y. Cellular registration without behavioral recall of olfactory sensory input under general anesthesia. Anesthesiology. 120: 890-905. PMID 24694846 DOI: 10.1097/Aln.0000000000000137  0.616
2014 Bondarenko V, Mowrey DD, Tillman TS, Seyoum E, Xu Y, Tang P. NMR structures of the human α7 nAChR transmembrane domain and associated anesthetic binding sites. Biochimica Et Biophysica Acta. 1838: 1389-95. PMID 24384062 DOI: 10.1016/J.Bbamem.2013.12.018  0.728
2014 Chiara DC, Gill JF, Chen Q, Tillman T, Dailey WP, Eckenhoff RG, Xu Y, Tang P, Cohen JB. Photoaffinity labeling the propofol binding site in GLIC. Biochemistry. 53: 135-42. PMID 24341978 DOI: 10.1021/Bi401492K  0.726
2014 Seyoum E, Tillman TS, Xu Y, Tang P. Functional Chimeras of the Human α7 Acetylcholine Receptor Provide Insights into Allosteric Modulation Biophysical Journal. 106: 342a. DOI: 10.1016/J.Bpj.2013.11.1953  0.708
2014 Mowrey DD, Liu Q, Bondarenko V, Chen Q, Seyoum E, Xu Y, Wu J, Tang P. Insights into the Distinctly Different Sensitivities of α7 and α7β2 nAChRs to the Volatile Anesthetic Isoflurane Biophysical Journal. 106: 341a. DOI: 10.1016/J.Bpj.2013.11.1952  0.698
2013 Mowrey DD, Liu Q, Bondarenko V, Chen Q, Seyoum E, Xu Y, Wu J, Tang P. Insights into distinct modulation of α7 and α7β2 nicotinic acetylcholine receptors by the volatile anesthetic isoflurane. The Journal of Biological Chemistry. 288: 35793-800. PMID 24194515 DOI: 10.1074/Jbc.M113.508333  0.715
2013 Wang HJ, Kleinhammes A, Tang P, Xu Y, Wu Y. Critical role of water in the binding of volatile anesthetics to proteins. The Journal of Physical Chemistry. B. 117: 12007-12. PMID 24050264 DOI: 10.1021/Jp407115J  0.669
2013 Mowrey DD, Cui T, Jia Y, Ma D, Makhov AM, Zhang P, Tang P, Xu Y. Open-channel structures of the human glycine receptor α1 full-length transmembrane domain. Structure (London, England : 1993). 21: 1897-904. PMID 23994010 DOI: 10.1016/J.Str.2013.07.014  0.739
2013 Mowrey D, Chen Q, Liang Y, Liang J, Xu Y, Tang P. Signal transduction pathways in the pentameric ligand-gated ion channels. Plos One. 8: e64326. PMID 23667707 DOI: 10.1371/Journal.Pone.0064326  0.729
2013 Mowrey D, Cheng MH, Liu LT, Willenbring D, Lu X, Wymore T, Xu Y, Tang P. Asymmetric ligand binding facilitates conformational transitions in pentameric ligand-gated ion channels. Journal of the American Chemical Society. 135: 2172-80. PMID 23339564 DOI: 10.1021/Ja307275V  0.74
2013 Bondarenko V, Mowrey D, Liu LT, Xu Y, Tang P. NMR resolved multiple anesthetic binding sites in the TM domains of the α4β2 nAChR. Biochimica Et Biophysica Acta. 1828: 398-404. PMID 23000369 DOI: 10.1016/J.Bbamem.2012.09.014  0.742
2013 Tillman T, Cheng MH, Chen Q, Tang P, Xu Y. Reversal of ion-charge selectivity renders the pentameric ligand-gated ion channel GLIC insensitive to anaesthetics. The Biochemical Journal. 449: 61-8. PMID 22978431 DOI: 10.1042/Bj20121072  0.734
2013 Mowrey DD, Liu Q, Bondarenko, Chen Q, Seyoum E, Xu Y, Wu J, Tang P. Insights into distinct modulation of alpha 7 and alpha 7 beta 2 nicotinic acetylcholine receptors by the volatile anesthetic isoflurane. Journal of Biological Chemistry. 288: 35793-35800. DOI: 10.2210/Pdb2Maw/Pdb  0.637
2013 Mowrey DD, Chen Q, Xu Y, Tang P. Mechanisms of Channel Activation in GLIC Biophysical Journal. 104: 67a. DOI: 10.1016/J.Bpj.2012.11.405  0.692
2013 Chen Q, Tillman TS, Xu Y, Tang P. Functional Modulation of the ELIC by General Anesthetics and Alcohols Biophysical Journal. 104: 635a. DOI: 10.1016/J.Bpj.2012.11.3511  0.663
2013 Bondarenko V, Mowrey D, Xu Y, Tang P. Anesthetic Binding Sites within the Transmembrane Domain of the α7 Nicotinic Acetylcholine Receptor Biophysical Journal. 104: 635a. DOI: 10.1016/J.Bpj.2012.11.3509  0.715
2013 Mowrey DD, Cheng MH, Liu LT, Willenbring D, Lu X, Wymore T, Xu Y, Tang P. Does Symmetry of Ligand Occupancy Matter to Conformational Transitions of Pentameric Ligand Gated Ion Channels? Biophysical Journal. 104: 380a. DOI: 10.1016/J.Bpj.2012.11.2116  0.726
2013 Kinde MN, Bondarenko V, Chen Q, Tillman TS, Xu Y, Tang P. ELIC Channel Conformational Changes Detected by 19F NMR Biophysical Journal. 104: 208a. DOI: 10.1016/J.Bpj.2012.11.1176  0.808
2013 Bondarenko V, Mowrey D, Xu Y, Tang P. Structures of α7 and α4β2 nAChR transmenbrane domains and associated binding sites for allosteric modulators Biochemical Pharmacology. 86: 1227. DOI: 10.1016/J.Bcp.2013.08.036  0.701
2013 Tillman TS, Seyoum E, Xu Y, Tang P. Functional chimera of the human α7 acetylcholine receptor for mechanistic investigations of allosteric modulation Biochemical Pharmacology. 86: 1226-1227. DOI: 10.1016/J.Bcp.2013.08.035  0.652
2012 Pan J, Chen Q, Willenbring D, Mowrey D, Kong XP, Cohen A, Divito CB, Xu Y, Tang P. Structure of the pentameric ligand-gated ion channel GLIC bound with anesthetic ketamine. Structure (London, England : 1993). 20: 1463-9. PMID 22958642 DOI: 10.1016/J.Str.2012.08.009  0.749
2012 Markley JL, Akutsu H, Asakura T, Baldus M, Boelens R, Bonvin A, Kaptein R, Bax A, Bezsonova I, Gryk MR, Hoch JC, Korzhnev DM, Maciejewski MW, Case D, Chazin WJ, ... ... Xu Y, et al. In support of the BMRB. Nature Structural & Molecular Biology. 19: 854-60. PMID 22955930 DOI: 10.1038/Nsmb.2371  0.563
2012 Pan J, Chen Q, Willenbring D, Yoshida K, Tillman T, Kashlan OB, Cohen A, Kong XP, Xu Y, Tang P. Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine. Nature Communications. 3: 714. PMID 22395605 DOI: 10.1038/Ncomms1703  0.745
2012 Bondarenko V, Mowrey D, Tillman T, Cui T, Liu LT, Xu Y, Tang P. NMR structures of the transmembrane domains of the α4β2 nAChR. Biochimica Et Biophysica Acta. 1818: 1261-8. PMID 22361591 DOI: 10.1016/J.Bbamem.2012.02.008  0.714
2012 Cui T, Mowrey D, Bondarenko V, Tillman T, Ma D, Landrum E, Perez-Aguilar JM, He J, Wang W, Saven JG, Eckenhoff RG, Tang P, Xu Y. NMR structure and dynamics of a designed water-soluble transmembrane domain of nicotinic acetylcholine receptor. Biochimica Et Biophysica Acta. 1818: 617-26. PMID 22155685 DOI: 10.1016/J.Bbamem.2011.11.021  0.73
2012 Xu Y, Mowrey D, Cui T, Perez-Aguilar J, Saven J, Eckenhoff R, Tang P. WSA major conformation Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Lkg/Pdb  0.647
2012 Xu Y, Mowrey D, Cui T, Perez-Aguilar J, Saven J, Eckenhoff R, Tang P. WSA minor conformation Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr17992  0.646
2012 Tang P, Pan J, Chen Q, Yoshida K, Willenbring D, Tillman T, Kashlan O, Cohen A, Kong X, Xu Y. Structure and Function of ELIC Bound with the Antagonist Acetylcholine Biophysical Journal. 102: 112a-113a. DOI: 10.1016/J.Bpj.2011.11.634  0.74
2011 Willenbring D, Liu LT, Mowrey D, Xu Y, Tang P. Isoflurane alters the structure and dynamics of GLIC. Biophysical Journal. 101: 1905-12. PMID 22004744 DOI: 10.1016/J.Bpj.2011.09.026  0.754
2011 Wang HJ, Kleinhammes A, Tang P, Xu Y, Wu Y. Temperature dependence of lysozyme hydration and the role of elastic energy. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 83: 031924. PMID 21517540 DOI: 10.1103/Physreve.83.031924  0.614
2011 Xiong W, Cheng K, Cui T, Godlewski G, Rice KC, Xu Y, Zhang L. Cannabinoid potentiation of glycine receptors contributes to cannabis-induced analgesia. Nature Chemical Biology. 7: 296-303. PMID 21460829 DOI: 10.1038/Nchembio.552  0.311
2011 Liu LT, Li M, Mowrey D, Lu H, Liang J, Xu Y, Tang P. Anesthetic Modulation of Signal Transduction Pathways in the α4β2 nAchR Revealed by the Perturbation-Based Markovian Transmission Model Biophysical Journal. 100: 548a. DOI: 10.1016/J.Bpj.2010.12.3193  0.733
2011 Bondarenko V, Tillman T, Liu LT, Xu Y, Tang P. NMR Study of General Anesthetic Interactions with the Neuronal N-Acetylcholine Receptor Transmembrane Domain Biophysical Journal. 100: 275a. DOI: 10.1016/J.Bpj.2010.12.1711  0.738
2011 Willenbring D, Tian Liu L, Xu Y, Tang P. Binding of Isoflurane to Glic Alters the Structure and Dynamics of the Protein Biophysical Journal. 100: 273a. DOI: 10.1016/J.Bpj.2010.12.1701  0.75
2010 Chen Q, Cheng MH, Xu Y, Tang P. Anesthetic binding in a pentameric ligand-gated ion channel: GLIC. Biophysical Journal. 99: 1801-9. PMID 20858424 DOI: 10.1016/J.Bpj.2010.07.023  0.745
2010 Willenbring D, Xu Y, Tang P. The role of structured water in mediating general anesthetic action on alpha4beta2 nAChR. Physical Chemistry Chemical Physics : Pccp. 12: 10263-9. PMID 20661501 DOI: 10.1039/C003573D  0.677
2010 Liu LT, Xu Y, Tang P. Mechanistic insights into xenon inhibition of NMDA receptors from MD simulations. The Journal of Physical Chemistry. B. 114: 9010-6. PMID 20560662 DOI: 10.1021/Jp101687J  0.71
2010 Mowrey D, Haddadian EJ, Liu LT, Willenbring D, Xu Y, Tang P. Unresponsive correlated motion in alpha7 nAChR to halothane binding explains its functional insensitivity to volatile anesthetics. The Journal of Physical Chemistry. B. 114: 7649-55. PMID 20465243 DOI: 10.1021/Jp1009675  0.697
2010 Bondarenko V, Tillman T, Xu Y, Tang P. NMR structure of the transmembrane domain of the n-acetylcholine receptor beta2 subunit. Biochimica Et Biophysica Acta. 1798: 1608-14. PMID 20441771 DOI: 10.1016/J.Bbamem.2010.04.014  0.713
2010 Liu LT, Haddadian EJ, Willenbring D, Xu Y, Tang P. Higher susceptibility to halothane modulation in open- than in closed-channel alpha4beta2 nAChR revealed by molecular dynamics simulations. The Journal of Physical Chemistry. B. 114: 626-32. PMID 20014754 DOI: 10.1021/Jp908944E  0.743
2010 Cui T, Canlas CG, Xu Y, Tang P. Anesthetic effects on the structure and dynamics of the second transmembrane domains of nAChR alpha4beta2. Biochimica Et Biophysica Acta. 1798: 161-6. PMID 19715664 DOI: 10.1016/J.Bbamem.2009.08.009  0.674
2010 Cui T, Tang P, Xu∗ Y. NMR of Transmembrane and Intracellular Domains of Human Nicotine Acetylcholine Receptor A7 Subunit Biophysical Journal. 98: 134a. DOI: 10.1016/J.Bpj.2009.12.723  0.685
2010 Bondarenko V, Tillman T, Xu Y, Tang P. Anesthetic Binding Sites in the Neuronal N-Acetylcholine Receptor Transmembrane Domain Biophysical Journal. 98: 133a. DOI: 10.1016/J.Bpj.2009.12.718  0.709
2010 Cheng MH, Xu Y, Coalson RD, Tang∗ P. Molecular Dynamics Investigation of Anesthetic Halothane Interactions with the Proton-Gated Ion Channel GLIC Biophysical Journal. 98: 703a. DOI: 10.1016/J.Bpj.2009.12.3857  0.727
2010 Chen Q, Cheng MH, Stevenson H, Xu Y, Tang P. Multisite Binding of Anesthetics to GLIC, a Pentameric Ligand-Gated Ion Channel Biophysical Journal. 98: 702a-703a. DOI: 10.1016/J.Bpj.2009.12.3855  0.718
2010 Mowrey DD, Liu LT, Willenbring D, Haddadian EJ, Xu Y, Tang P. Why Is α4β2 Nachr More Sensitive to Volatile Anesthetics Than α7 Nachr? Biophysical Journal. 98: 38a. DOI: 10.1016/J.Bpj.2009.12.218  0.724
2009 Liu LT, Willenbring D, Xu Y, Tang P. General anesthetic binding to neuronal alpha4beta2 nicotinic acetylcholine receptor and its effects on global dynamics. The Journal of Physical Chemistry. B. 113: 12581-9. PMID 19697903 DOI: 10.1021/Jp9039513  0.735
2009 Xu Y, Liachenko SM, Tang P, Chan PH. Faster recovery of cerebral perfusion in SOD1-overexpressed rats after cardiac arrest and resuscitation. Stroke; a Journal of Cerebral Circulation. 40: 2512-8. PMID 19461023 DOI: 10.1161/Strokeaha.109.548453  0.603
2009 Cheng MH, Xu Y, Tang P. Anionic lipid and cholesterol interactions with alpha4beta2 nAChR: insights from MD simulations. The Journal of Physical Chemistry. B. 113: 6964-70. PMID 19419220 DOI: 10.1021/Jp900714B  0.698
2009 Cheng MH, Haddadian E, Xu Y, Tang P. Interactions between POPA and a4b2 nAChR: Insight from MD Simulations Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.3225  0.724
2009 Cui T, Tang P, Saven JG, Eckenhoff RG, Xu Y. NMR Structure of Water-Solubilized Transmembrane Domain of Nicotinic Acetylcholine Receptor Biophysical Journal. 96: 429a. DOI: 10.1016/J.Bpj.2008.12.2197  0.721
2009 Ma D, Jia Y, Tang P, Xu Y. Structure and Dynamics of TM Domains of Human Glycine Receptor in LPPG Micelles Biophysical Journal. 96: 195a. DOI: 10.1016/J.Bpj.2008.12.1045  0.711
2008 Ma D, Tillman TS, Tang P, Meirovitch E, Eckenhoff R, Carnini A, Xu Y. NMR studies of a channel protein without membranes: structure and dynamics of water-solubilized KcsA. Proceedings of the National Academy of Sciences of the United States of America. 105: 16537-42. PMID 18948596 DOI: 10.1073/Pnas.0805501105  0.687
2008 Haddadian EJ, Cheng MH, Coalson RD, Xu Y, Tang P. In silico models for the human alpha4beta2 nicotinic acetylcholine receptor. The Journal of Physical Chemistry. B. 112: 13981-90. PMID 18847252 DOI: 10.1021/Jp804868S  0.731
2008 Canlas CG, Cui T, Li L, Xu Y, Tang P. Anesthetic modulation of protein dynamics: insight from an NMR study. The Journal of Physical Chemistry. B. 112: 14312-8. PMID 18821786 DOI: 10.1021/Jp805952W  0.694
2008 Canlas CG, Ma D, Tang P, Xu Y. Residual dipolar coupling measurements of transmembrane proteins using aligned low-q bicelles and high-resolution magic angle spinning NMR spectroscopy. Journal of the American Chemical Society. 130: 13294-300. PMID 18788737 DOI: 10.1021/Ja802578Z  0.653
2008 Ma D, Brandon NR, Cui T, Bondarenko V, Canlas C, Johansson JS, Tang P, Xu Y. Four-alpha-helix bundle with designed anesthetic binding pockets. Part I: structural and dynamical analyses. Biophysical Journal. 94: 4454-63. PMID 18310240 DOI: 10.1529/biophysj.107.117838  0.693
2008 Cui T, Bondarenko V, Ma D, Canlas C, Brandon NR, Johansson JS, Xu Y, Tang P. Four-alpha-helix bundle with designed anesthetic binding pockets. Part II: halothane effects on structure and dynamics. Biophysical Journal. 94: 4464-72. PMID 18310239 DOI: 10.1529/Biophysj.107.117853  0.719
2008 Bondarenko V, Yushmanov VE, Xu Y, Tang P. NMR study of general anesthetic interaction with nAChR beta2 subunit. Biophysical Journal. 94: 1681-8. PMID 17993502 DOI: 10.1529/Biophysj.107.116772  0.699
2008 Ma D, Xu Y, Tillman T, Tang P, Meirovitch E, Eckenhoff R, Carnini A. Solubilization of transmembrane proteins in water: structural studies of a water-soluble analogue of the potassium channel KcsA Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr15677  0.666
2007 Cheng MH, Liu LT, Saladino AC, Xu Y, Tang P. Molecular dynamics simulations of ternary membrane mixture: phosphatidylcholine, phosphatidic acid, and cholesterol. The Journal of Physical Chemistry. B. 111: 14186-92. PMID 18052271 DOI: 10.1021/Jp075467B  0.656
2007 Szarecka A, Xu Y, Tang P. Dynamics of heteropentameric nicotinic acetylcholine receptor: implications of the gating mechanism. Proteins. 68: 948-60. PMID 17546671 DOI: 10.1002/Prot.21462  0.708
2007 Szarecka A, Xu Y, Tang P. Dynamics of firefly luciferase inhibition by general anesthetics: Gaussian and anisotropic network analyses. Biophysical Journal. 93: 1895-905. PMID 17513367 DOI: 10.1529/Biophysj.106.102780  0.674
2007 Bondarenko V, Xu Y, Tang P. Structure of the first transmembrane domain of the neuronal acetylcholine receptor beta2 subunit. Biophysical Journal. 92: 1616-22. PMID 17142275 DOI: 10.1529/Biophysj.106.095364  0.703
2007 Ma D, Brandon NR, Cui T, Bondarenko V, Canlas C, Johansson JS, Tang P, Xu Y. Structural and Dynamical Analysis of a Four-Alpha-Helix Bundle with Designed Anesthetic Binding Pockets Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2I7U/Pdb  0.674
2006 Liu Z, Xu Y, Tang P. Steered molecular dynamics simulations of Na+ permeation across the gramicidin A channel. The Journal of Physical Chemistry. B. 110: 12789-95. PMID 16800614 DOI: 10.1021/Jp060688N  0.702
2005 Yonkunas MJ, Xu Y, Tang P. Anesthetic interaction with ketosteroid isomerase: insights from molecular dynamics simulations. Biophysical Journal. 89: 2350-6. PMID 16040747 DOI: 10.1529/Biophysj.105.063396  0.688
2005 Ma D, Liu Z, Li L, Tang P, Xu Y. Structure and dynamics of the second and third transmembrane domains of human glycine receptor. Biochemistry. 44: 8790-800. PMID 15952785 DOI: 10.1021/Bi050256N  0.697
2005 Liu Z, Xu Y, Tang P. Molecular dynamics simulations of C2F6 effects on gramicidin A: implications of the mechanisms of general anesthesia. Biophysical Journal. 88: 3784-91. PMID 15764669 DOI: 10.1529/Biophysj.104.055566  0.705
2005 Saladino AC, Xu Y, Tang P. Homology modeling and molecular dynamics simulations of transmembrane domain structure of human neuronal nicotinic acetylcholine receptor. Biophysical Journal. 88: 1009-17. PMID 15574706 DOI: 10.1529/Biophysj.104.053421  0.701
2004 Liu Z, Xu Y, Saladino AC, Wymore T, Tang P. Parametrization of 2-bromo-2-chloro-1,1,1-trifluoroethane (halothane) and hexafluoroethane for nonbonded interactions Journal of Physical Chemistry A. 108: 781-786. DOI: 10.1021/Jp0368482  0.615
2003 Yushmanov VE, Xu Y, Tang P. NMR structure and dynamics of the second transmembrane domain of the neuronal acetylcholine receptor beta 2 subunit. Biochemistry. 42: 13058-65. PMID 14596621 DOI: 10.1021/Bi0350396  0.679
2003 Liachenko S, Tang P, Xu Y. Deferoxamine improves early postresuscitation reperfusion after prolonged cardiac arrest in rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 23: 574-81. PMID 12771572 DOI: 10.1097/01.Wcb.0000057742.00152.3F  0.619
2003 Yushmanov VE, Mandal PK, Liu Z, Tang P, Xu Y. NMR structure and backbone dynamics of the extended second transmembrane domain of the human neuronal glycine receptor alpha1 subunit. Biochemistry. 42: 3989-95. PMID 12667090 DOI: 10.1021/Bi026767G  0.677
2003 Yushmanov V, Mandal P, Liu Z, Tang P, Xu Y. NMR Structure of the Extended Second Transmembrane Domain of the Human Neuronal Glycine Receptor alpha1 Subunit in SDS Micelles Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr5607  0.674
2002 Homanics GE, Xu Y, Tang P. Integrated approaches to the action of general anesthetics and alcohol. Physiology & Behavior. 77: 495-9. PMID 12526989 DOI: 10.1016/S0031-9384(02)00910-1  0.602
2002 Tang P, Xu Y. Large-scale molecular dynamics simulations of general anesthetic effects on the ion channel in the fully hydrated membrane: the implication of molecular mechanisms of general anesthesia. Proceedings of the National Academy of Sciences of the United States of America. 99: 16035-40. PMID 12438684 DOI: 10.1073/Pnas.252522299  0.704
2002 Xu Y, Yushmanov VE, Tang P. NMR studies of drug interaction with membranes and membrane-associated proteins. Bioscience Reports. 22: 175-96. PMID 12428900 DOI: 10.1023/A:1020182404940  0.639
2002 Tang P, Mandal PK, Xu Y. NMR structures of the second transmembrane domain of the human glycine receptor alpha(1) subunit: model of pore architecture and channel gating. Biophysical Journal. 83: 252-62. PMID 12080117 DOI: 10.1016/S0006-3495(02)75166-7  0.724
2002 Wang L, Yushmanov VE, Liachenko SM, Tang P, Hamilton RL, Xu Y. Late reversal of cerebral perfusion and water diffusion after transient focal ischemia in rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 253-61. PMID 11891430 DOI: 10.1097/00004647-200203000-00002  0.611
2002 Xu Y, Liachenko S, Tang P. Dependence of early cerebral reperfusion and long-term outcome on resuscitation efficiency after cardiac arrest in rats. Stroke; a Journal of Cerebral Circulation. 33: 837-43. PMID 11872912 DOI: 10.1161/Hs0302.104198  0.6
2002 Yushmanov VE, Wang L, Liachenko S, Tang P, Xu Y. ADC characterization of region-specific response to cerebral perfusion deficit in rats by MRI at 9.4 T. Magnetic Resonance in Medicine. 47: 562-70. PMID 11870844 DOI: 10.1002/Mrm.10103  0.621
2001 Liachenko S, Tang P, Hamilton RL, Xu Y. Regional dependence of cerebral reperfusion after circulatory arrest in rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 21: 1320-9. PMID 11702047 DOI: 10.1097/00004647-200111000-00008  0.627
2001 Tang P, Zubrzycki I, Xu Y. Ab initio calculation of structures and properties of halogenated general anesthetics: halothane and sevoflurane Journal of Computational Chemistry. 22: 802-802. DOI: 10.1002/jcc.1044  0.605
2000 Tang P, Eckenhoff RG, Xu Y. General anesthetic binding to gramicidin A: the structural requirements. Biophysical Journal. 78: 1804-9. PMID 10733961 DOI: 10.1016/S0006-3495(00)76730-0  0.696
2000 Xu Y, Seto T, Tang P, Firestone L. NMR study of volatile anesthetic binding to nicotinic acetylcholine receptors. Biophysical Journal. 78: 746-51. PMID 10653787 DOI: 10.1016/S0006-3495(00)76632-X  0.686
2000 Tang P, Zubrzycki I, Xu Y. Room 309, 10/18/2000 9: 00 AM - 10: 30 AM (PD) A Closer Look at Volatile Anesthetic Interaction with Ion Channel: One Femtosecond a Time  Anesthesiology. 93: A-145. DOI: 10.1097/00000542-200009001-00145  0.658
2000 Zubrzycki I, Xu Y, Tang P. Room 302, 10/16/2000 9: 00 AM - 10: 30 AM (PD) Creator's View of Anesthetics:  Anesthesiology. 93: A-121. DOI: 10.1097/00000542-200009001-00121  0.593
2000 Zubrzycki IZ, Xu Y, Madrid M, Tang P. Molecular dynamics simulations of a fully hydrated dimyristoylphosphatidylcholine membrane in liquid-crystalline phase Journal of Chemical Physics. 112: 3437-3441. DOI: 10.1063/1.480924  0.634
1999 Tang P, Hu J, Liachenko S, Xu Y. Distinctly different interactions of anesthetic and nonimmobilizer with transmembrane channel peptides. Biophysical Journal. 77: 739-46. PMID 10423422 DOI: 10.1016/S0006-3495(99)76928-6  0.66
1999 Liachenko S, Tang P, Somogyi GT, Xu Y. Concentration-dependent isoflurane effects on depolarization-evoked glutamate and GABA outflows from mouse brain slices. British Journal of Pharmacology. 127: 131-8. PMID 10369465 DOI: 10.1038/Sj.Bjp.0702543  0.618
1999 Tang P, Simplaceanu V, Xu Y. Structural consequences of anesthetic and nonimmobilizer interaction with gramicidin A channels. Biophysical Journal. 76: 2346-50. PMID 10233053 DOI: 10.1016/S0006-3495(99)77391-1  0.704
1999 Xu Y, Tang P, Liachenko S. Unifying characteristics of sites of anesthetic action revealed by combined use of anesthetics and non-anesthetics. Toxicology Letters. 347-52. PMID 10049163 DOI: 10.1016/S0378-4274(98)00205-7  0.697
1998 Tang P, Liachenko S, Melick JA, Xu Y. [31P]/[1H] nuclear magnetic resonance study of mitigating effects of GYKI 52466 on kainate-induced metabolic impairment in perfused rat cerebrocortical slices. Epilepsia. 39: 577-83. PMID 9637598 DOI: 10.1111/J.1528-1157.1998.Tb01424.X  0.617
1998 Liachenko S, Tang P, Hamilton RL, Xu Y. A reproducible model of circulatory arrest and remote resuscitation in rats for NMR investigation. Stroke; a Journal of Cerebral Circulation. 29: 1229-38; discussion . PMID 9626299 DOI: 10.1161/01.Str.29.6.1229  0.625
1998 Liachenko S, Tang P, Somogyi GT, Xu Y. Comparison of anaesthetic and non-anaesthetic effects on depolarization-evoked glutamate and GABA release from mouse cerebrocortical slices. British Journal of Pharmacology. 123: 1274-80. PMID 9559915 DOI: 10.1038/Sj.Bjp.0701728  0.632
1998 Liachenko S, Tang P, Somogyi GT, Xu Y. DIFFERENT ISOFLURANE EC50 FOR INHIBITION OF RELEASE AND RE-UPTAKE OF NEUROTRANSMITTERS Anesthesiology. 89: 125A. DOI: 10.1097/00000542-199809040-00029  0.605
1997 Tang P, Yan B, Xu Y. Different distribution of fluorinated anesthetics and nonanesthetics in model membrane: a 19F NMR study. Biophysical Journal. 72: 1676-82. PMID 9083671 DOI: 10.1016/S0006-3495(97)78813-1  0.643
1997 Xu Y, Tang P. Amphiphilic sites for general anesthetic action? Evidence from 129Xe-[1H] intermolecular nuclear Overhauser effects. Biochimica Et Biophysica Acta. 1323: 154-162. PMID 9030222 DOI: 10.1016/S0005-2736(96)00184-8  0.666
1997 Xu Y, Liachenko S, Tang P. A604 AN OUTCOME MODEL OF PROLONGED CARDIAC ARREST AND RESUSCITATION FOR CEREBRAL PERFUSION MRI Anesthesiology. 87: 604A. DOI: 10.1097/00000542-199709001-00604  0.603
1997 Tang P, Liachenko S, Xu Y. A601 BRAIN ADC MAPPING AFTER RESUSCITATION FROM ASPHYXIAL CARDIAC ARREST Anesthesiology. 87: 601A. DOI: 10.1097/00000542-199709001-00601  0.599
1997 Liachenko S, Tang P, Somogyi GT, Xu Y. A331 ANESTHETIC AND NONANESTHETIC EFFECTS ON GLUTAMATE AND GABA RELEASE Anesthesiology. 87: 331A. DOI: 10.1097/00000542-199709001-00331  0.608
1996 Xu Y, Tang P, Firestone L, Zhang TT. 19F nuclear magnetic resonance investigation of stereoselective binding of isoflurane to bovine serum albumin. Biophysical Journal. 70: 532-8. PMID 8770230 DOI: 10.1016/S0006-3495(96)79599-1  0.676
1995 Xu Y, Tang P, Zhang W, Firestone L, Winter PM. Fluorine-19 nuclear magnetic resonance imaging and spectroscopy of sevoflurane uptake, distribution, and elimination in rat brain. Anesthesiology. 83: 766-74. PMID 7574056 DOI: 10.1097/00000542-199510000-00016  0.628
Low-probability matches (unlikely to be authored by this person)
2012 Xiong W, Cui T, Cheng K, Yang F, Chen SR, Willenbring D, Guan Y, Pan HL, Ren K, Xu Y, Zhang L. Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors. The Journal of Experimental Medicine. 209: 1121-34. PMID 22585736 DOI: 10.1084/Jem.20120242  0.287
1989 Xu Y, Barbara TM, Rooney WD, Springer CS. Two-dimensional multiple-quantum NMR spectroscopy of isolated half-integer spin systems. II. 35Cl examples Journal of Magnetic Resonance. 83: 279-298. DOI: 10.1016/0022-2364(89)90191-1  0.254
1990 Chu K‐C, Xu Y, Balschi JA, Springer CS. Bulk magnetic susceptibility shifts in nmr studies of compartmentalized samples: use of paramagnetic reagents Magnetic Resonance in Medicine. 13: 239-262. PMID 2156125 DOI: 10.1002/Mrm.1910130207  0.253
2013 Xu K, Tzvetkova-Robev D, Xu Y, Goldgur Y, Chan YP, Himanen JP, Nikolov DB. Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5. Proceedings of the National Academy of Sciences of the United States of America. 110: 14634-9. PMID 23959867 DOI: 10.1073/Pnas.1311000110  0.247
1997 Bedu-Addo FK, Tang P, Xu Y, Huang L. Effects of polyethyleneglycol chain length and phospholipid acyl chain composition on the interaction of polyethyleneglycol-phospholipid conjugates with phospholipid: implications in liposomal drug delivery. Pharmaceutical Research. 13: 710-7. PMID 8860425 DOI: 10.1023/A:1016091314940  0.242
2019 Zhang M, Yu X, Xu Y, Guo RT, Swapna GVT, Szyperski T, Hunt JF, Montelione GT. The Structural Basis by Which the N-terminal Polypeptide Segment of Rhizopus chinensis Lipase Regulates Its Substrate Binding Affinity. Biochemistry. PMID 31436959 DOI: 10.1021/Acs.Biochem.9B00462  0.24
2021 Xu Y, Robev D, Saha N, Wang B, Dalva MB, Xu K, Himanen JP, Nikolov DB. The Ephb2 Receptor Uses Homotypic, Head-to-Tail Interactions within Its Ectodomain as an Autoinhibitory Control Mechanism. International Journal of Molecular Sciences. 22. PMID 34638814 DOI: 10.3390/ijms221910473  0.239
2013 Li L, Ding C, Duan JL, Yang MF, Sun Y, Wang XQ, Xu Y. A new functional site W115 in CdtA is critical for Aggregatibacter actinomycetemcomitans cytolethal distending toxin. Plos One. 8: e65729. PMID 23755273 DOI: 10.1371/journal.pone.0065729  0.237
2021 Yang F, Guo L, Li Y, Wang G, Wang J, Zhang C, Fang GX, Chen X, Liu L, Yan X, Liu Q, Qu C, Xu Y, Xiao P, Zhu Z, et al. Structure, function and pharmacology of human itch receptor complexes. Nature. PMID 34789875 DOI: 10.1038/s41586-021-04077-y  0.236
1990 Xu Y, Balschi JA, Springer CS. Magnetic susceptibility shift selected imaging: MESSI. Magnetic Resonance in Medicine. 16: 80-90. PMID 2255239 DOI: 10.1002/Mrm.1910160109  0.235
2014 Xu K, Wu Z, Renier N, Antipenko A, Tzvetkova-Robev D, Xu Y, Minchenko M, Nardi-Dei V, Rajashankar KR, Himanen J, Tessier-Lavigne M, Nikolov DB. Neural migration. Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism. Science (New York, N.Y.). 344: 1275-9. PMID 24876346 DOI: 10.1126/Science.1255149  0.222
2015 Xu Y, Matsumoto N, Wu Q, Shimatani Y, Kawata H. Site-specific nanopatterning of functional metallic and molecular arbitrary features in nanofluidic channels. Lab On a Chip. 15: 1989-93. PMID 25786899 DOI: 10.1039/c5lc00190k  0.221
2019 Zhu S, Meng Q, Schooley RT, An J, Xu Y, Huang Z. Structural and Biological Characterizations of Novel High-Affinity Fluorescent Probes with Overlapped and Distinctive Binding Regions on CXCR4. Molecules (Basel, Switzerland). 24. PMID 31412600 DOI: 10.3390/Molecules24162928  0.221
2009 Kubo K, Nakao S, Jomura S, Sakamoto S, Miyamoto E, Xu Y, Tomimoto H, Inada T, Shingu K. Edaravone, a free radical scavenger, mitigates both gray and white matter damages after global cerebral ischemia in rats Brain Research. 1279: 139-146. PMID 19410562 DOI: 10.1016/J.Brainres.2009.04.045  0.221
2019 Xu Y, Li S, Yan Z, Ge B, Huang F, Yue T. Revealing Cooperation between Knotted Conformation and Dimerization in Protein Stabilization by Molecular Dynamics Simulations. The Journal of Physical Chemistry Letters. 5815-5822. PMID 31525988 DOI: 10.1021/acs.jpclett.9b02209  0.22
2008 Hirko AC, Dallasen R, Jomura S, Xu Y. Modulation of inflammatory responses after global ischemia by transplanted umbilical cord matrix stem cells. Stem Cells (Dayton, Ohio). 26: 2893-901. PMID 18719227 DOI: 10.1634/Stemcells.2008-0075  0.22
2023 Tan J, Xu Y, Wang X, Yan F, Xian W, Liu X, Chen Y, Zhu Y, Zhou Y. Molecular basis of threonine ADP-ribosylation of ubiquitin by bacterial ARTs. Nature Chemical Biology. PMID 37945894 DOI: 10.1038/s41589-023-01475-3  0.218
2007 Jomura S, Uy M, Mitchell K, Dallasen R, Bode CJ, Xu Y. Potential treatment of cerebral global ischemia with Oct-4+ umbilical cord matrix cells. Stem Cells (Dayton, Ohio). 25: 98-106. PMID 16960128 DOI: 10.1634/Stemcells.2006-0055  0.215
2015 Fu X, Xu Y, Wu C, Moy VT, Zhang XF. Anchorage-dependent binding of integrin I-domain to adhesion ligands. Journal of Molecular Recognition : Jmr. 28: 385-92. PMID 25707989 DOI: 10.1002/jmr.2453  0.214
2008 Zhang R, Zhu G, Zhang W, Cao S, Ou X, Li X, Bartlam M, Xu Y, Zhang XC, Rao Z. Crystal structure of a carbonyl reductase from Candida parapsilosis with anti-Prelog stereospecificity. Protein Science : a Publication of the Protein Society. 17: 1412-23. PMID 18566346 DOI: 10.1110/ps.035089.108  0.211
2017 Wang X, Chi H, Li S, Xu Y. Binding of CXCR4 Transmembrane Peptides to the Bacterial Chaperonin GroEL. Protein and Peptide Letters. PMID 28741466 DOI: 10.2174/0929866524666170724162529  0.209
2020 Xu Y, Pan Y, Li L, Zhou M. Dually Labeled Biomolecules for Characterizing Biotinylated Species through Competitive Binding Reactions. Acs Omega. 5: 32591-32596. PMID 33376896 DOI: 10.1021/acsomega.0c04877  0.206
1997 Xu Y, Tang P. Easy fabrication of a tunable high-pass birdcage resonator Magnetic Resonance in Medicine. 38: 168-172. PMID 9211393 DOI: 10.1002/Mrm.1910380123  0.204
2022 Fang X, Meng Q, Zhang H, Fang X, Huang LS, Zhang X, Schooley RT, Ciechanover A, An J, Xu Y, Huang Z. A fragment integrational approach to GPCR inhibition: Identification of a high affinity small molecule CXCR4 antagonist. European Journal of Medicinal Chemistry. 231: 114150. PMID 35124530 DOI: 10.1016/j.ejmech.2022.114150  0.204
2013 Han X, Xu Y, Yang Y, Xi J, Tian W, Duggineni S, Huang Z, An J. Discovery and characterization of a novel cyclic peptide that effectively inhibits ephrin binding to the EphA4 receptor and displays anti-angiogenesis activity. Plos One. 8: e80183. PMID 24265799 DOI: 10.1371/Journal.Pone.0080183  0.203
2013 Xu Y, Li Y, Han Y, Song X, Yu J. A gallogermanate zeolite with eleven-membered-ring channels. Angewandte Chemie (International Ed. in English). 52: 5501-3. PMID 23576422 DOI: 10.1002/anie.201300846  0.202
2022 Li Y, Zhang R, Wang C, Forouhar F, Clarke OB, Vorobiev S, Singh S, Montelione GT, Szyperski T, Xu Y, Hunt JF. Oligomeric interactions maintain active-site structure in a noncooperative enzyme family. The Embo Journal. e108368. PMID 35801308 DOI: 10.15252/embj.2021108368  0.202
2011 Dallasen RM, Bowman JD, Xu Y. Isoflurane does not cause neuroapoptosis but reduces astroglial processes in young adult mice. Medical Gas Research. 1: 27. PMID 22146123 DOI: 10.1186/2045-9912-1-27  0.202
2019 Liang J, Zhang S, Wang W, Xu Y, Kawuli A, Lu J, Xiu X. Long non-coding RNA DSCAM-AS1 contributes to the tumorigenesis of cervical cancer by targeting miR-877-5p/ATXN7L3 axis. Bioscience Reports. PMID 31737900 DOI: 10.1042/Bsr20192061  0.201
2018 Xu Y, Li P, Nie J, Zhao Q, Guan S, Kuai Z, Qiao Y, Jiang X, Li Y, Li W, Shi Y, Kong W, Shan Y. Humanization and directed evolution of the selenium-containing phage abzyme. Rsc Advances. 8: 17218-17223. PMID 35539266 DOI: 10.1039/c8ra02798f  0.199
2013 Xu K, Xu Y, Rajashankar KR, Robev D, Nikolov DB. Crystal structures of Lgr4 and its complex with R-spondin1. Structure (London, England : 1993). 21: 1683-9. PMID 23891289 DOI: 10.1016/J.Str.2013.07.001  0.198
2022 Sun Z, Zhou N, Zhang W, Xu Y, Yao YF. Dual role of CsrA in regulating the hemolytic activity of O157:H7. Virulence. 13: 859-874. PMID 35609307 DOI: 10.1080/21505594.2022.2073023  0.197
2021 Wood CAP, Zhang J, Aydin D, Xu Y, Andreone BJ, Langen UH, Dror RO, Gu C, Feng L. Structure and mechanism of blood-brain-barrier lipid transporter MFSD2A. Nature. PMID 34349262 DOI: 10.1038/s41586-021-03782-y  0.196
2023 Gu J, Xu Y, Nie Y. Role of distal sites in enzyme engineering. Biotechnology Advances. 63: 108094. PMID 36621725 DOI: 10.1016/j.biotechadv.2023.108094  0.194
2021 Xu Y, Kang R, Ren L, Yang L, Yue T. Revealing Topological Barriers against Knot Untying in Thermal and Mechanical Protein Unfolding by Molecular Dynamics Simulations. Biomolecules. 11. PMID 34827686 DOI: 10.3390/biom11111688  0.194
2020 Fang X, Meng Q, Zhang H, Liang B, Zhu S, Wang J, Zhang C, Huang LS, Zhang X, Schooley RT, An J, Xu Y, Huang Z. Design, synthesis, and biological characterization of a new class of symmetrical polyamine-based small molecule CXCR4 antagonists. European Journal of Medicinal Chemistry. 200: 112410. PMID 32492596 DOI: 10.1016/J.Ejmech.2020.112410  0.192
2012 Tkachenko E, Tse D, Sideleva O, Deharvengt SJ, Luciano MR, Xu Y, McGarry CL, Chidlow J, Pilch PF, Sessa WC, Toomre DK, Stan RV. Caveolae, fenestrae and transendothelial channels retain PV1 on the surface of endothelial cells. Plos One. 7: e32655. PMID 22403691 DOI: 10.1371/Journal.Pone.0032655  0.192
2001 Zhou Y, Zhu H, Chen Z, Chen M, Xu Y, Zhang H, Zhao D. A Large 24-Membered-Ring Germanate Zeolite-Type Open-Framework Structure with Three-Dimensional Intersecting Channels. Angewandte Chemie (International Ed. in English). 40: 2166-2168. PMID 29712199 DOI: 10.1002/1521-3773(20010601)40:11<2166::Aid-Anie2166>3.0.Co;2-C  0.192
2019 Wang X, Jing X, Deng Y, Nie Y, Xu F, Xu Y, Zhao YL, Hunt JF, Montelione GT, Szyperski T. Evolutionary coupling saturation mutagenesis: Coevolution-guided identification of distant sites influencing Bacillus naganoensis pullulanase activity. Febs Letters. PMID 31665817 DOI: 10.1002/1873-3468.13652  0.191
2004 Inase A, Kodama TS, Sharif J, Xu Y, Ayame H, Sugiyama H, Iwai S. Binding of distamycin A to UV-damaged DNA. Journal of the American Chemical Society. 126: 11017-23. PMID 15339187 DOI: 10.1021/JA048851K  0.187
2017 Fishovitz J, Sha Z, Chilakala S, Cheng I, Xu Y, Lee I. Utilization of Mechanistic Enzymology to Evaluate the Significance of ADP Binding to Human Lon Protease. Frontiers in Molecular Biosciences. 4: 47. PMID 28744459 DOI: 10.3389/Fmolb.2017.00047  0.186
2013 Xu Y, Liu L, Chevrier DM, Sun J, Zhang P, Yu J. Germanate with three-dimensional 12 × 12 × 11-ring channels solved by X-ray powder diffraction with charge-flipping algorithm. Inorganic Chemistry. 52: 10238-44. PMID 23402209 DOI: 10.1021/ic302705f  0.185
2012 Choi WT, Duggineni S, Xu Y, Huang Z, An J. Drug discovery research targeting the CXC chemokine receptor 4 (CXCR4). Journal of Medicinal Chemistry. 55: 977-94. PMID 22085380 DOI: 10.1021/Jm200568C  0.185
2022 Fan T, Liang B, Nie L, Wang J, Zhang H, Ciechanover A, Xu Y, An J, Huang Z. A synthetic bivalent peptide ligand of EphB4 with potent agonistic activity. European Journal of Medicinal Chemistry. 244: 114804. PMID 36208510 DOI: 10.1016/j.ejmech.2022.114804  0.185
2014 Wang S, Nie Y, Xu Y, Zhang R, Ko TP, Huang CH, Chan HC, Guo RT, Xiao R. Unconserved substrate-binding sites direct the stereoselectivity of medium-chain alcohol dehydrogenase. Chemical Communications (Cambridge, England). 50: 7770-2. PMID 24834985 DOI: 10.1039/C4Cc01752H  0.182
2013 Duggineni S, Mitra S, Noberini R, Han X, Lin N, Xu Y, Tian W, An J, Pasquale EB, Huang Z. Design, synthesis and characterization of novel small molecular inhibitors of ephrin-B2 binding to EphB4. Biochemical Pharmacology. 85: 507-13. PMID 23253822 DOI: 10.1016/J.Bcp.2012.12.005  0.182
2021 Gu J, Sim BR, Li J, Yu Y, Qin L, Wu L, Shen Y, Nie Y, Zhao YL, Xu Y. Evolutionary coupling-inspired engineering of alcohol dehydrogenase reveals the influence of distant sites on its catalytic efficiency for stereospecific synthesis of chiral alcohols. Computational and Structural Biotechnology Journal. 19: 5864-5873. PMID 34815831 DOI: 10.1016/j.csbj.2021.10.031  0.181
2023 Meng Q, Zhu R, Mao Y, Zhu S, Wu Y, Huang LSM, Ciechanover A, An J, Xu Y, Huang Z. Biological and mutational analyses of CXCR4-antagonist interactions and design of new antagonistic analogs. Bioscience Reports. 43. PMID 38131305 DOI: 10.1042/BSR20230981  0.179
2007 Matsugami A, Xu Y, Noguchi Y, Sugiyama H, Katahira M. Structure of a human telomeric DNA sequence stabilized by 8-bromoguanosine substitutions, as determined by NMR in a K+ solution. The Febs Journal. 274: 3545-3556. PMID 17561958 DOI: 10.1111/j.1742-4658.2007.05881.x  0.179
2016 Gao ZH, Chen FJ, Xu L, Sun L, Xu Y, Du HB. A Stable Extra-Large-Pore Zeolite with Intersecting 14- and 10-Membered-Ring Channels. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27533626 DOI: 10.1002/chem.201602419  0.179
2007 Xu Y, Yamazaki S, Osuga H, Sugiyama H. The recognition of higher-order G-quadruplex by chiral cyclic-helicene molecules. Nucleic Acids Symposium Series (2004). 183-4. PMID 17150878 DOI: 10.1093/NASS/NRL091  0.177
2013 Zhang D, Lu Y, Zhu D, Xu Y. (C4N2H12)3[Ln3(OH)(SO4)7] (Ln = Sm, Eu, and Tb): a series of honeycomb-like open-framework lanthanide sulfates with extra-large channels containing 24-membered rings. Inorganic Chemistry. 52: 3253-8. PMID 23464507 DOI: 10.1021/ic3027682  0.177
2018 Chi H, Xu B, Liu Z, Wei J, Li S, Ren H, Xu Y, Lu X, Wang X, Wang X, Huang F. Combined thermodynamic and kinetic analysis of GroEL interacting with CXCR4 transmembrane peptides. Biochimica Et Biophysica Acta. PMID 29627450 DOI: 10.1016/J.Bbagen.2018.04.002  0.176
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2013 Xu Y, Duggineni S, Espitia S, Richman DD, An J, Huang Z. A synthetic bivalent ligand of CXCR4 inhibits HIV infection. Biochemical and Biophysical Research Communications. 435: 646-50. PMID 23688427 DOI: 10.1016/J.Bbrc.2013.05.038  0.133
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2021 Xu Y, Tian Y, Wang Y, Yang J, Li F, Wan X, Ouyang M. Human antigen R (HuR) and Cold inducible RNA-binding protein (CIRP) influence intestinal mucosal barrier function in ulcerative colitis by competitive regulation on Claudin1. Biofactors (Oxford, England). PMID 33638934 DOI: 10.1002/biof.1719  0.132
2021 Liu J, Yu X, Xu Y, Zhao Y, Li D. Quaternary Ammonium-Mediated Delamination of Europium-Based Metal-Organic Framework into Ultrathin Nanosheets for the Selective Photoelectrochemical Sensing of Fe. Inorganic Chemistry. PMID 34855389 DOI: 10.1021/acs.inorgchem.1c02895  0.132
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2023 Guan J, Lu Y, Dai Z, Zhao S, Xu Y, Nie Y. R97 at "Handlebar" Binding Mode in Active Pocket Plays an Important Role in Fe(II)/α-Ketoglutaric Acid-Dependent Dioxygenase -P3H-Mediated Selective Synthesis of (2S,3R)-3-Hydroxypipecolic Acid. Molecules (Basel, Switzerland). 28. PMID 36838840 DOI: 10.3390/molecules28041854  0.131
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2018 Xu Y, Pitkänen L, Maina NH, Coda R, Katina K, Tenkanen M. Interactions between fava bean protein and dextrans produced by Leuconostoc pseudomesenteroides DSM 20193 and Weissella cibaria Sj 1b. Carbohydrate Polymers. 190: 315-323. PMID 29628253 DOI: 10.1016/j.carbpol.2018.02.082  0.128
2022 Shi X, Wu D, Xu Y, Yu X. Engineering the optimum pH of β-galactosidase from Aspergillus oryzae for efficient hydrolysis of lactose. Journal of Dairy Science. PMID 35450720 DOI: 10.3168/jds.2021-21760  0.128
2016 Zhang M, Yu XW, Swapna GV, Xiao R, Zheng H, Sha C, Xu Y, Montelione GT. Efficient production of (2)H, (13)C, (15)N-enriched industrial enzyme Rhizopus chinensis lipase with native disulfide bonds. Microbial Cell Factories. 15: 123. PMID 27411547 DOI: 10.1186/S12934-016-0522-7  0.128
2022 Mozar F, Sharma V, Gorityala S, Albert JM, Xu Y, Montano MM. Downregulation of Dihydrotestosterone and Estradiol Levels by HEXIM1. Endocrinology. 163. PMID 34864989 DOI: 10.1210/endocr/bqab236  0.128
2023 Zhou S, Chen M, Yuan Y, Xu Y, Pu Q, Ai X, Liu S, Du F, Huang X, Dong J, Cui X, Tang Z. acting aptazyme for conditional gene knockdown in eukaryotic cells. Molecular Therapy. Nucleic Acids. 33: 367-375. PMID 37547296 DOI: 10.1016/j.omtn.2023.07.014  0.127
2012 Gong G, Xu Y, Zhou Y, Meng Z, Ren G, Zhao Y, Zhang X, Wu J, Hu Y. Molecular switch for the assembly of lipophilic drug incorporated plasma protein nanoparticles and in vivo image. Biomacromolecules. 13: 23-8. PMID 22029860 DOI: 10.1021/bm201401s  0.127
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2023 Tan Y, Cheng C, Zheng C, Zeng W, Yang X, Xu Y, Zhang Z, Ma Z, Xu Y, Cao X. Activation of mGlu receptors in the striatum alleviates L-DOPA-induced dyskinesia and inhibits abnormal postsynaptic molecular expression. Pharmacology, Biochemistry, and Behavior. 231: 173637. PMID 37714223 DOI: 10.1016/j.pbb.2023.173637  0.127
2021 Wang G, Zhou Q, Xu Y, Zhao B. Emerging Roles of Pleckstrin-2 Beyond Cell Spreading. Frontiers in Cell and Developmental Biology. 9: 768238. PMID 34869363 DOI: 10.3389/fcell.2021.768238  0.127
2023 Lyu J, Wang S, Ma Y, Xu Y, Tang K. Study on the interaction of tannins and salivary proteins affecting wine aroma volatility: Static HS-SPME and molecular dynamics simulation approaches. Food Research International (Ottawa, Ont.). 175: 113809. PMID 38129011 DOI: 10.1016/j.foodres.2023.113809  0.126
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2021 Wang J, Liu X, Du Z, Xu Y. Organo-functionalized polyoxovanadates: crystal architecture and property aspects. Dalton Transactions (Cambridge, England : 2003). PMID 34008655 DOI: 10.1039/d1dt00494h  0.126
2023 Qin L, Su X, Wang J, Wu L, Zou M, Gu J, Xu Y, Nie Y. Regulating the stereoselectivity of medium-chain dehydrogenase/reductase by creating an additional active pocket accommodating prochiral heterocyclic ketones. Chemical Communications (Cambridge, England). PMID 37846488 DOI: 10.1039/d3cc04361d  0.126
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2007 Cheng L, Xu X, Xu Y. Bis(1-adamantylammonium) hexafluoridogermanate. Acta Crystallographica. Section E, Structure Reports Online. 64: m82. PMID 21200651 DOI: 10.1107/S1600536807063702  0.126
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2023 Yao H, Liu T, Zou R, Ding S, Xu Y. A Spatial-Temporal Transformer Architecture using multi-channel signals for Sleep Stage Classification. Ieee Transactions On Neural Systems and Rehabilitation Engineering : a Publication of the Ieee Engineering in Medicine and Biology Society. PMID 37578925 DOI: 10.1109/TNSRE.2023.3305201  0.125
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2020 Zheng C, Xu Y, Chen G, Tan Y, Zeng W, Wang J, Cheng C, Yang X, Nie S, Zhang Z, Cao X. Distinct anti-dyskinetic effects of amantadine and group II metabotropic glutamate receptor agonist LY354740 in a rodent model: An electrophysiological perspective. Neurobiology of Disease. 104807. PMID 32088382 DOI: 10.1016/j.nbd.2020.104807  0.124
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2015 Xu Y, Xu B. An Integrated Glass Nanofluidic Device Enabling In-situ Electrokinetic Probing of Water Confined in a Single Nanochannel under Pressure-Driven Flow Conditions. Small (Weinheim An Der Bergstrasse, Germany). PMID 26485695 DOI: 10.1002/smll.201502125  0.12
2012 Cheng Z, Liu H, Yu N, Wang F, An G, Xu Y, Liu Q, Guan CB, Ayrton A. Hydrophilic anti-migraine triptans are substrates for OATP1A2, a transporter expressed at human blood-brain barrier. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 42: 880-90. PMID 22509823 DOI: 10.3109/00498254.2012.675455  0.12
2021 Hu XX, Wang SQ, Gan SQ, Liu L, Zhong MQ, Jia MH, Jiang F, Xu Y, Xiao CD, Shen XC. A Small Ligand That Selectively Binds to the G-quadruplex at the Human Vascular Endothelial Growth Factor Internal Ribosomal Entry Site and Represses the Translation. Frontiers in Chemistry. 9: 781198. PMID 34858949 DOI: 10.3389/fchem.2021.781198  0.12
2024 Fu X, Zhang C, Xu Y, Zhang Y, Sun H. Statistical Machine Learning for Power Flow Analysis Considering the Influence of Weather Factors on Photovoltaic Power Generation. Ieee Transactions On Neural Networks and Learning Systems. PMID 38587954 DOI: 10.1109/TNNLS.2024.3382763  0.12
2024 Guo Y, Su J, Jiang S, Xu Y, Dou B, Li T, Zhu J, He K. Transcriptomics and metabonomics study on the effect of exercise combined with curcumin supplementation on breast cancer in mice. Heliyon. 10: e28807. PMID 38576560 DOI: 10.1016/j.heliyon.2024.e28807  0.12
2024 Xu Y, Dai Q, Zhang D, Zhang F, Yue F, Ye J, Liu C, Zeng X, Lan W. Improving the Monophenolic Yield of Lignin Depolymerization in Dualistic Aprotic Solvent System by Organic Solvent Fractionation. Chemsuschem. e202400378. PMID 38570922 DOI: 10.1002/cssc.202400378  0.12
2024 Yin Y, Xu Y, Zhang H, Zheng H, Xu Z, Xu C, Zuo G, Yang S, He H, Liu Y. Interfacial tuning in FeP/ZnInS Ohm heterojunction: Enhanced photocatalytic hydrogen production via Zn-P charge bridging. Journal of Colloid and Interface Science. PMID 38570207 DOI: 10.1016/j.jcis.2024.03.194  0.12
2024 Yao D, Qi J, Xu Y, Bai H. Combination of lauromacrogol and bleomycin in the treatment of low-flow vascular malformations: a web-based meta-analysis. Panminerva Medica. PMID 38563604 DOI: 10.23736/S0031-0808.24.05115-2  0.12
2024 Shi Q, Chen Y, Xu Y, Chen C, Lu H. Engineering a functional ACL reconstruction graft containing a triphasic enthesis-like structure in bone tunnel for the enhancement of graft-to-bone integration. Journal of Orthopaedic Translation. 45: 155-167. PMID 38559900 DOI: 10.1016/j.jot.2024.01.004  0.12
2024 de Winter MA, Xu Y, Stacey D, Wells PS. Qualitative experiences, values, and decisional needs of patients with unprovoked venous thromboembolism who suffer bleeding-"This pill will keep you alive tonight". Research and Practice in Thrombosis and Haemostasis. 8: 102360. PMID 38559571 DOI: 10.1016/j.rpth.2024.102360  0.12
2024 Manzoor MA, Xu Y, Lv Z, Xu J, Shah IH, Sabir IA, Wang Y, Sun W, Liu X, Wang L, Liu R, Jiu S, Zhang C. Horticulture crop under pressure: Unraveling the impact of climate change on nutrition and fruit cracking. Journal of Environmental Management. 357: 120759. PMID 38554453 DOI: 10.1016/j.jenvman.2024.120759  0.12
2024 Bhattacharya S, Myers JA, Baker C, Guo M, Danopoulos S, Myers JR, Bandyopadhyay G, Romas ST, Huyck HL, Misra RS, Dutra J, Holden-Wiltse J, McDavid AN, Ashton JM, Al Alam D, ... ... Xu Y, et al. Single-Cell Transcriptomic Profiling Identifies Molecular Phenotypes of Newborn Human Lung Cells. Genes. 15. PMID 38540357 DOI: 10.3390/genes15030298  0.12
2024 Xu Y, Xu HY, Shan LW, Liu Y, Cao MC, Jin LG, Dong LM. Photocatalysis Meets Piezoelectricity in a Type-I Oxygen Vacancy-Rich BaTiO/BiOBr Heterojunction: Mechanism Insights from Characterizations to DFT Calculations. Inorganic Chemistry. PMID 38532637 DOI: 10.1021/acs.inorgchem.4c00378  0.12
2024 Chen QN, Bai BQ, Xu Y, Mei Q, Liu XC. Sporadic gastrinoma with refractory benign esophageal stricture: A case report. World Journal of Clinical Cases. 12: 1284-1289. PMID 38524517 DOI: 10.12998/wjcc.v12.i7.1284  0.12
2024 Xu Y, Chen J. Activity and recyclability enhancement of pH-dependent Fe@BC-mediated heterogeneous sodium percarbonate (SPC)-reducing agents (RA) system. Journal of Environmental Management. 356: 120596. PMID 38520858 DOI: 10.1016/j.jenvman.2024.120596  0.12
2024 Jiang Y, Hu L, Wang B, Zhang B, Shao M, Meng L, Xu Y, Chen R, Li M, Du C. Disrupting PIAS3-mediated SUMOylation of MLK3 ameliorates poststroke neuronal damage and deficits in cognitive and sensorimotor behaviors. Cellular and Molecular Life Sciences : Cmls. 81: 119. PMID 38456949 DOI: 10.1007/s00018-024-05166-7  0.12
2004 Xu Y, Sugiyama H. Highly efficient photochemical 2'-deoxyribonolactone formation at the diagonal loop of a 5-iodouracil-containing antiparallel G-quartet. Journal of the American Chemical Society. 126: 6274-9. PMID 15149224 DOI: 10.1021/JA031942H  0.12
2008 McCulloch M, Zhou X, Xu Y, Brunell S, Spear L. Determination of endocannabinoid receptor antagonist SR141716 (rimonabant) in plasma by liquid chromatograph tandem mass spectrometry Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 863: 258-265. PMID 18258497 DOI: 10.1016/j.jchromb.2008.01.020  0.12
2019 Luo XM, Li NF, Hu ZB, Cao JP, Cui CH, Lin QF, Xu Y. Polyoxometalate-Based Well-Defined Rodlike Structural Multifunctional Materials: Synthesis, Structure, and Properties. Inorganic Chemistry. PMID 30714376 DOI: 10.1021/acs.inorgchem.8b03021  0.12
2014 Xu Y, Wen X, Shao XJ, Deng NY, Chou KC. iHyd-PseAAC: predicting hydroxyproline and hydroxylysine in proteins by incorporating dipeptide position-specific propensity into pseudo amino acid composition. International Journal of Molecular Sciences. 15: 7594-610. PMID 24857907 DOI: 10.3390/ijms15057594  0.119
2003 Xu Y, Sugiyama H. Photoreactivity of 5-iodouracil-containing telomeric DNA. Nucleic Acids Research. Supplement (2001). 71-2. PMID 14510385 DOI: 10.1093/NASS/3.1.71  0.119
2018 Mao Y, Meng Q, Song P, Zhu S, Xu Y, Snyder EY, An J, Huang Z. Novel Bivalent and D-Peptide Ligands of CXCR4 Mobilize Hematopoietic Progenitor Cells to the Blood in C3H/HeJ Mice. Cell Transplantation. 963689718784957. PMID 29991278 DOI: 10.1177/0963689718784957  0.119
2005 Zaslavsky A, Li S, Xu Y. Sphingosine-1-phosphate induces a PDGFR-dependent cell detachment via inhibiting beta1 integrin in HEK293 cells. Febs Letters. 579: 3899-906. PMID 15987639 DOI: 10.1016/j.febslet.2005.06.006  0.119
2018 Guo Y, Zhang L, Muhammad N, Xu Y, Zhou Y, Tang F, Yang S. Chiral Silver-Lanthanide Metal-Organic Frameworks Comprised of One-Dimensional Triple Right-Handed Helical Chains Based on [Ln7(μ3-OH)8]13+ Clusters. Inorganic Chemistry. PMID 29319311 DOI: 10.1021/acs.inorgchem.7b02324  0.119
2016 Xu Y, Chou KC. Recent Progress in Predicting Posttranslational Modification Sites in Proteins. Current Topics in Medicinal Chemistry. 16: 591-603. PMID 26286211 DOI: 10.2174/1568026615666150819110421  0.118
2019 Xu Y, Xue Y, Cao J, Cheng W. 3D enantiomorphic Mg(II)-based metal-organic frameworks as chemical sensor of nitrobenzene and efficient catalyst for the CO2 cycloaddition. Chemistry, An Asian Journal. PMID 30884145 DOI: 10.1002/asia.201900147  0.118
2016 Yu XW, Xu Y, Xiao R. Lipases from the genus Rhizopus: Characteristics, expression, protein engineering and application. Progress in Lipid Research. PMID 27497512 DOI: 10.1016/J.Plipres.2016.08.001  0.118
2014 Yu XW, Zhu SS, Xiao R, Xu Y. Conversion of a Rhizopus chinensis lipase into an esterase by lid swapping. Journal of Lipid Research. 55: 1044-1051. PMID 24670990 DOI: 10.1194/jlr.M043950  0.118
2022 Xu Y, Wang Y, Du J, Pei S, Guo S, Hao R, Wang D, Zhou G, Li S, O'Neill M, Hu R, Kong Y. A DE1 BINDING FACTOR 1-GLABRA2 module regulates rhamnogalacturonan I biosynthesis in Arabidopsis seed coat mucilage. The Plant Cell. PMID 35038740 DOI: 10.1093/plcell/koac011  0.118
2009 Xu Y, Gao Y. [In vitro cross-linking of Escherichia coli tartrate dehydratase beta subunit]. Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology. 24: 1485-9. PMID 18998556  0.117
2022 Xu Y, Yang Q, Xue B, Wang X, Tian R, Deng R, Chen S, Wang X, Wang L, Wang C, Chen J, You R, Liu Q, Li H, Wang J, et al. Heat Shock-Binding Protein 21 Regulates the Innate Immune Response to Viral Infection. Journal of Virology. e0000122. PMID 35254105 DOI: 10.1128/jvi.00001-22  0.117
2002 Zhou HW, Xu Y, Zhou HM. Activity and conformational changes of horseradish peroxidase in trifluoroethanol. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 80: 205-13. PMID 11989716 DOI: 10.1139/o02-003  0.117
2018 Cao JP, Shen FC, Luo XM, Cui CH, Lan YQ, Xu Y. Proton conductivity resulting from different triazole-based ligands in two new bifunctional decavanadates. Rsc Advances. 8: 18560-18566. PMID 35541148 DOI: 10.1039/c8ra02694g  0.117
2024 Song M, Li S, Zhu Y, Wan H, Xu X, Li L, Sun L, Tian L, Xu Y. Highly stable and reversible Zn anodes enabled by an electrolyte additive of sucrose. Dalton Transactions (Cambridge, England : 2003). PMID 38226467 DOI: 10.1039/d3dt04031c  0.116
2012 Xu Y, Quinn CC. MIG-10 functions with ABI-1 to mediate the UNC-6 and SLT-1 axon guidance signaling pathways. Plos Genetics. 8: e1003054. PMID 23209429 DOI: 10.1371/Journal.Pgen.1003054  0.116
2021 Wang S, Xu Y, Yu XW. Micro-Aqueous Organic System: A Neglected Model in Computational Lipase Design? Biomolecules. 11. PMID 34200257 DOI: 10.3390/biom11060848  0.116
2014 Wang L, Wei J, Zou Y, Xu K, Wang Y, Cui L, Xu Y. Molecular characteristics and biochemical functions of VpPR10s from Vitis pseudoreticulata associated with biotic and abiotic stresses. International Journal of Molecular Sciences. 15: 19162-82. PMID 25340981 DOI: 10.3390/ijms151019162  0.116
2018 Yang Y, Wang H, Ding J, Xu Y. iAcet-Sumo: Identification of lysine acetylation and sumoylation sites in proteins by multi-class transformation methods. Computers in Biology and Medicine. 100: 144-151. PMID 30015011 DOI: 10.1016/j.compbiomed.2018.07.006  0.116
2021 Milewski D, Shukla S, Gryder BE, Pradhan A, Donovan J, Sudha P, Vallabh S, Pyros A, Xu Y, Barski A, Szabo S, Turpin B, Pressey JG, Millay DP, Khan J, et al. FOXF1 is required for the oncogenic properties of PAX3-FOXO1 in rhabdomyosarcoma. Oncogene. PMID 33627785 DOI: 10.1038/s41388-021-01694-9  0.116
2015 Amlie-Wolf A, Ryvkin P, Tong R, Dragomir I, Suh E, Xu Y, Van Deerlin VM, Gregory BD, Kwong LK, Trojanowski JQ, Lee VM, Wang LS, Lee EB. Transcriptomic Changes Due to Cytoplasmic TDP-43 Expression Reveal Dysregulation of Histone Transcripts and Nuclear Chromatin. Plos One. 10: e0141836. PMID 26510133 DOI: 10.1371/Journal.Pone.0141836  0.116
2019 Xu Y, Huang R, Liu H, Yan T, Ding W, Jiang Y, Wang P, Zheng D, Xu J. New Polyketides from the Marine-Derived Fungus sp. 5XNZ4-2. Marine Drugs. 18. PMID 31878313 DOI: 10.3390/Md18010018  0.116
2020 Wang Y, Xu Y, Pei S, Lu M, Kong Y, Zhou G, Hu R. KNAT7 modulates xylan biosynthesis in Arabidopsis seed coat mucilage. Journal of Experimental Botany. PMID 32277756 DOI: 10.1093/jxb/eraa189  0.115
2021 Miao L, Xu Y, Jia C, Zhang B, Niu M, Zhao S. Structural changes of rice starch and activity inhibition of starch digestive enzymes by anthocyanins retarded starch digestibility. Carbohydrate Polymers. 261: 117841. PMID 33766339 DOI: 10.1016/j.carbpol.2021.117841  0.115
2013 Xu Y, Komiyama M. Evidence for G-quadruplex DNA in human cells. Chembiochem : a European Journal of Chemical Biology. 14: 927-8. PMID 23619895 DOI: 10.1002/cbic.201300157  0.115
2016 Xu Y, Ding YX, Ding J, Wu LY, Xue Y. Mal-Lys: prediction of lysine malonylation sites in proteins integrated sequence-based features with mRMR feature selection. Scientific Reports. 6: 38318. PMID 27910954 DOI: 10.1038/srep38318  0.115
2016 Ma L, Huang C, Wang XJ, Xin DE, Wang LS, Zou QC, Zhang YS, Tan MD, Wang YM, Zhao TC, Chatterjee D, Altura RA, Wang C, Xu YS, Yang JH, et al. Lysyl Oxidase 3 Is a Dual-Specificity Enzyme Involved in STAT3 Deacetylation and Deacetylimination Modulation. Molecular Cell. PMID 28065600 DOI: 10.1016/J.Molcel.2016.12.002  0.115
2023 Lu Y, Jia C, Niu M, Xu Y, Zhao S. The in-situ dextran produced in rice protein yogurt: Effect on viscosity and structural characteristics. Carbohydrate Polymers. 311: 120767. PMID 37028860 DOI: 10.1016/j.carbpol.2023.120767  0.115
2013 Xu K, Rockx B, Xie Y, DeBuysscher BL, Fusco DL, Zhu Z, Chan YP, Xu Y, Luu T, Cer RZ, Feldmann H, Mokashi V, Dimitrov DS, Bishop-Lilly KA, Broder CC, et al. Crystal structure of the Hendra virus attachment G glycoprotein bound to a potent cross-reactive neutralizing human monoclonal antibody. Plos Pathogens. 9: e1003684. PMID 24130486 DOI: 10.1371/Journal.Ppat.1003684  0.114
2015 Fan Q, Cai Q, Xu Y. FOXM1 is a downstream target of LPA and YAP oncogenic signaling pathways in high grade serous ovarian cancer. Oncotarget. 6: 27688-99. PMID 26299613 DOI: 10.18632/oncotarget.4280  0.114
2020 Bi J, Chen S, Zhao X, Nie Y, Xu Y. Computation-aided engineering of starch-debranching pullulanase from Bacillus thermoleovorans for enhanced thermostability. Applied Microbiology and Biotechnology. PMID 32632476 DOI: 10.1007/s00253-020-10764-z  0.114
2009 Xu Y, Zhang Z, Qin K, Papa SM, Cao X. Quantitative autoradiographic study on receptor regulation in the basal ganglia in rat model of levodopa-induced motor complications. Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban. 29: 156-62. PMID 19399396 DOI: 10.1007/s11596-009-0204-3  0.114
2021 Zhou F, Xu Y, Mu X, Nie Y. A Sustainable Approach for Synthesizing ()-4-Aminopentanoic Acid From Levulinic Acid Catalyzed by Structure-Guided Tailored Glutamate Dehydrogenase. Frontiers in Bioengineering and Biotechnology. 9: 770302. PMID 35083200 DOI: 10.3389/fbioe.2021.770302  0.114
2021 Yum JH, Ishizuka T, Fukumoto K, Hori D, Bao HL, Xu Y, Sugiyama H, Park S. Systematic Approach to DNA Aptamer Design Using Amino Acid-Nucleic Acid Hybrids (ANHs) Targeting Thrombin. Acs Biomaterials Science & Engineering. PMID 33756075 DOI: 10.1021/acsbiomaterials.1c00060  0.114
2014 Zhou F, Xu Y, Hou XY. MLK3-MKK3/6-P38MAPK cascades following N-methyl-D-aspartate receptor activation contributes to amyloid-β peptide-induced apoptosis in SH-SY5Y cells. Journal of Neuroscience Research. 92: 808-17. PMID 24482239 DOI: 10.1002/jnr.23354  0.113
2012 Yi X, Zhong B, Smith KM, Geldenhuys WJ, Feng Y, Pink JJ, Dowlati A, Xu Y, Zhou A, Su B. Identification of a class of novel tubulin inhibitors. Journal of Medicinal Chemistry. 55: 3425-35. PMID 22435708 DOI: 10.1021/Jm300100D  0.113
2022 Xiang G, Fu Q, Li G, Liu R, Liu G, Yin X, Chen T, Xu Y. The cytosolic iron-sulphur cluster assembly mechanism in grapevine is one target of a virulent Crinkler effector from Plasmopara viticola. Molecular Plant Pathology. PMID 36071584 DOI: 10.1111/mpp.13266  0.113
2013 Fang Z, Su W, Zhang W, Xu Y, Xiong Y, Luo M, Fan J, Yin X. Chiral discrimination and interaction mechanism between enantiomers and serum albumins. Journal of Molecular Recognition : Jmr. 26: 161-4. PMID 23456739 DOI: 10.1002/jmr.2247  0.113
2014 Xu Y, Wang X, Wang Y, Tian Y, Shao X, Wu LY, Deng N. Prediction of posttranslational modification sites from amino acid sequences with kernel methods. Journal of Theoretical Biology. 344: 78-87. PMID 24291233 DOI: 10.1016/j.jtbi.2013.11.012  0.113
2023 Xu Y, Komiyama M. G-Quadruplexes in Human Telomere: Structures, Properties, and Applications. Molecules (Basel, Switzerland). 29. PMID 38202757 DOI: 10.3390/molecules29010174  0.113
2022 Liu Z, Zhang R, Zhang W, Xu Y. Structure-based rational design of hydroxysteroid dehydrogenases for improving and diversifying steroid synthesis. Critical Reviews in Biotechnology. 1-17. PMID 35834355 DOI: 10.1080/07388551.2022.2054770  0.113
2013 Bridges JP, Ludwig MG, Mueller M, Kinzel B, Sato A, Xu Y, Whitsett JA, Ikegami M. Orphan G protein-coupled receptor GPR116 regulates pulmonary surfactant pool size. American Journal of Respiratory Cell and Molecular Biology. 49: 348-57. PMID 23590306 DOI: 10.1165/rcmb.2012-0439OC  0.113
2020 Han YM, Li NF, Yu YZ, Cao JP, Yang MX, Hong YL, Kang RK, Yuan P, Xu Y. Synthesis, crystal structures and magnetic properties of two heterometallic {LnCr} (Ln = Gd and Tb) complexes with one-dimensional wave chain structure. Rsc Advances. 10: 11365-11370. PMID 35495346 DOI: 10.1039/d0ra01524e  0.112
2023 Yin TJ, Xu K, He L, Meng X, Xu Y, Men JT, Mu J, Ye Q, Shi PP. Templating influence of regulated inorganic framework in two-dimensional ferroelastic perovskites: (C3H5CH2NH3)2[MCl4] (M = Mn and Cd). Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 36598368 DOI: 10.1002/chem.202203606  0.112
2019 Xu Y, Liu Y, Hu X, Qin R, Su H, Li J, Yang P. Synthesis of 2D ultralarge protein supramolecular nanofilm by chemoselective thiol-disulfide exchange and emergent functions. Angewandte Chemie (International Ed. in English). PMID 31802603 DOI: 10.1002/anie.201912848  0.112
2014 Xu Y, Tao Y, Cheung LS, Fan C, Chen LQ, Xu S, Perry K, Frommer WB, Feng L. Structures of bacterial homologues of SWEET transporters in two distinct conformations. Nature. 515: 448-52. PMID 25186729 DOI: 10.1038/Nature13670  0.112
2023 Xiang XY, Zhou JL, Wang Q, Zhu YH, Zhang ZT, Ye TC, Wang JL, Chen QL, Xu Y. Layered Co-O Cluster Applied to Photocatalytic CO Reduction. Inorganic Chemistry. PMID 36959113 DOI: 10.1021/acs.inorgchem.3c00184  0.112
2011 Wang Y, Li J, Xu Y. Characterization of novel β-glucosidases with transglycosylation properties from Trichosporon asahii. Journal of Agricultural and Food Chemistry. 59: 11219-27. PMID 21916502 DOI: 10.1021/jf203693v  0.111
2017 Bao HL, Ishizuka T, Sakamoto T, Fujimoto K, Uechi T, Kenmochi N, Xu Y. Characterization of human telomere RNA G-quadruplex structures in vitro and in living cells using 19F NMR spectroscopy. Nucleic Acids Research. PMID 28180296 DOI: 10.1093/nar/gkx109  0.111
2018 Deng L, Chen L, Zhao L, Xu Y, Peng X, Wang X, Ding L, Jin J, Teng H, Wang Y, Pan W, Yu F, Liao L, Li L, Ge X, et al. Ubiquitination of Rheb governs growth factor-induced mTORC1 activation. Cell Research. PMID 30514904 DOI: 10.1038/s41422-018-0120-9  0.111
2017 Zhang M, Yu XW, Swapna GVT, Liu G, Xiao R, Xu Y, Montelione GT. Backbone and Ile-δ1, Leu, Val methyl (1)H, (15)N, and (13)C, chemical shift assignments for Rhizopus chinensis lipase. Biomolecular Nmr Assignments. PMID 28929427 DOI: 10.1007/S12104-017-9781-4  0.111
2023 Xu Y, Xiong Y, Liu Y, Li G, Bai T, Zheng G, Hou X, Song J. Activation of goblet cell Piezo1 alleviates mucus barrier damage in mice exposed to WAS by inhibiting H3K9me3 modification. Cell & Bioscience. 13: 7. PMID 36631841 DOI: 10.1186/s13578-023-00952-5  0.111
2021 Lu Z, Huang L, Li Y, Xu Y, Zhang R, Zhou Q, Sun Q, Lu Y, Chen J, Shen Y, Li J, Zhao B. Fine-Tuning of Cholesterol Homeostasis Controls Erythroid Differentiation. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2102669. PMID 34739188 DOI: 10.1002/advs.202102669  0.111
2006 Zhang Z, Lee YC, Kim SJ, Choi MS, Tsai PC, Xu Y, Xiao YJ, Zhang P, Heffer A, Mukherjee AB. Palmitoyl-protein thioesterase-1 deficiency mediates the activation of the unfolded protein response and neuronal apoptosis in INCL. Human Molecular Genetics. 15: 337-46. PMID 16368712 DOI: 10.1093/hmg/ddi451  0.11
2023 Zong G, Cao G, Fu J, Zhang P, Chen X, Yan W, Xin L, Wang Z, Xu Y, Zhang R. Novel mechanism of hydrogen peroxide for promoting efficient natamycin synthesis in . Microbiology Spectrum. e0087923. PMID 37695060 DOI: 10.1128/spectrum.00879-23  0.11
2018 Zhang H, Fang X, Meng Q, Mao Y, Xu Y, Fan T, An J, Huang Z. Design, synthesis and characterization of potent microtubule inhibitors with dual anti-proliferative and anti-angiogenic activities. European Journal of Medicinal Chemistry. 157: 380-396. PMID 30099258 DOI: 10.1016/J.Ejmech.2018.07.043  0.11
2019 Xu Y, Zhang Q, Li P, Hong G, Wang D, Liu J, Zhou H, Chai G, Lu B, He S, Zhang W, Sun S, Zhang J, Mao J. Nicotine Pharmacokinetics in Rat Brain and Blood by Simultaneous Microdialysis, Stable-isotope Labeling and UHPLC-HRMS: Determination of Nicotine Metabolites. Analytical Chemistry. PMID 30657674 DOI: 10.1021/acs.analchem.8b05078  0.11
2024 Yuan T, Zhao S, Yang J, Niu M, Xu Y. Structural characteristics of β-glucans from various sources and their influences on the short- and long-term starch retrogradation in wheat flour. International Journal of Biological Macromolecules. 264: 130561. PMID 38431011 DOI: 10.1016/j.ijbiomac.2024.130561  0.11
2006 Schützhold R, Uhlmann M, Xu Y, Fischer UR. Sweeping from the superfluid to the Mott phase in the Bose-Hubbard model. Physical Review Letters. 97: 200601. PMID 17155669 DOI: 10.1103/PhysRevLett.97.200601  0.11
2018 Wang X, Nie Y, Xu Y. Tailoring of active sites lining the catalytic pocket improves the activity and stability of starch-debranching pullulanase from Bacillus naganoensis. Journal of Agricultural and Food Chemistry. PMID 30499289 DOI: 10.1021/acs.jafc.8b06002  0.11
2010 Jiang W, Gao Y, Sun Y, Ding F, Xu Y, Bian Z, Li F, Bian J, Huang C. Zwitterionic iridium complexes: synthesis, luminescent properties, and their application in cell imaging. Inorganic Chemistry. 49: 3252-60. PMID 20210360 DOI: 10.1021/Ic9021239  0.109
2009 Neumann M, Kwong LK, Lee EB, Kremmer E, Flatley A, Xu Y, Forman MS, Troost D, Kretzschmar HA, Trojanowski JQ, Lee VM. Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies. Acta Neuropathologica. 117: 137-49. PMID 19125255 DOI: 10.1007/S00401-008-0477-9  0.109
2012 Xu Y, Jin JH, Wang Y, Wang RR, Li Z, Chen J. [Facilitation of synaptic transmission and connections of entorhinal-hippocampal pathway by 5-HT2C receptor subtype: multi-electrode array recordings]. Sheng Li Xue Bao : [Acta Physiologica Sinica]. 64: 259-68. PMID 22717628  0.109
2009 Qiao CJ, Ding D, Li J, Gu L, Xu Y, Fan YT. Synthesis, crystal structure and electrochemical properties of a novel tetranuclear silver(I) cluster based on 1,1′-bis[(2-hydroxybenzylidene)thiocarbonohydrazono-1-ethyl] ferrocene (FcL) Inorganic Chemistry Communications. 12: 1057-1060. DOI: 10.1016/j.inoche.2009.08.020  0.109
2009 Kimura T, Xu Y, Komiyama M. Human telomeric RNA r(UAGGGU) sequence forms parallel tetraplex structure with U-quartet Nucleic Acids Symposium Series (2004). 239-240. PMID 19749349 DOI: 10.1093/nass/nrp120  0.109
2014 Xiao S, Yosef N, Yang J, Wang Y, Zhou L, Zhu C, Wu C, Baloglu E, Schmidt D, Ramesh R, Lobera M, Sundrud MS, Tsai PY, Xiang Z, Wang J, ... Xu Y, et al. Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms. Immunity. 40: 477-89. PMID 24745332 DOI: 10.1016/J.Immuni.2014.04.004  0.108
2020 Wang L, Zhao S, Kong J, Li N, Qiao D, Zhang B, Xu Y, Jia C. Changing cooking mode can slow the starch digestion of colored brown rice: A view of starch structural changes during cooking. International Journal of Biological Macromolecules. PMID 32224181 DOI: 10.1016/j.ijbiomac.2020.03.203  0.108
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2020 Yu Y, Pan X, Cui C, Luo X, Li N, Mei H, Xu Y. A Series Three-Dimensional LnCr (Ln = Gd, Tb, Er) Heterometallic Cluster-Based Coordination Polymers Containing Interesting Nanotubes Exhibiting High Magnetic Entropy. Inorganic Chemistry. PMID 32227928 DOI: 10.1021/acs.inorgchem.0c00281  0.108
2013 Ma J, Chen M, Xia SK, Shu W, Guo Y, Wang YH, Xu Y, Bai XM, Zhang L, Zhang H, Zhang M, Wang YP, Leng J. Prostaglandin E2 promotes liver cancer cell growth by the upregulation of FUSE-binding protein 1 expression. International Journal of Oncology. 42: 1093-104. PMID 23338277 DOI: 10.3892/ijo.2013.1782  0.108
2021 Porta S, Xu Y, Lehr T, Zhang B, Meymand E, Olufemi M, Stieber A, Lee EB, Trojanowski JQ, Lee VM. Distinct Brain-derived TDP-43 Strains from FTLD-TDP Subtypes Induce Diverse Morphological TDP-43 Aggregates and Spreading Patterns in vitro and in vivo. Neuropathology and Applied Neurobiology. PMID 33971027 DOI: 10.1111/nan.12732  0.108
2015 Xu Y, Taru H, Jin Y, Quinn CC. SYD-1C, UNC-40 (DCC) and SAX-3 (Robo) function interdependently to promote axon guidance by regulating the MIG-2 GTPase. Plos Genetics. 11: e1005185. PMID 25876065 DOI: 10.1371/Journal.Pgen.1005185  0.108
2019 Wu M, Lu P, Yang Y, Liu L, Wang H, Xu Y, Chu J. LipoSVM: Prediction of Lysine Lipoylation in Proteins based on the Support Vector Machine. Current Genomics. 20: 362-370. PMID 32476993 DOI: 10.2174/1389202919666191014092843  0.108
2016 Han C, Nie S, Chen G, Ma K, Xiong N, Zhang Z, Xu Y, Wang T, Papa SM, Cao X. Intrastriatal injection of ionomycin profoundly changes motor response to L-DOPA and its underlying molecular mechanisms. Neuroscience. PMID 27771532 DOI: 10.1016/j.neuroscience.2016.10.033  0.108
2019 Li S, Yan Z, Luo Z, Xu Y, Huang F, Zhang X, Yi X, Yue T. Mechanics of the Formation, Interaction, and Evolution of Membrane Tubular Structures. Biophysical Journal. PMID 30795870 DOI: 10.1016/J.Bpj.2019.01.032  0.108
2022 Li YR, Liu FF, Liu WB, Zhang YF, Tian XY, Fu XJ, Xu Y, Song J, Zhang SY. A novel aromatic amide derivative SY-65 co-targeted tubulin and histone deacetylase 1 with potent anticancer activity in vitro and in vivo. Biochemical Pharmacology. 201: 115070. PMID 35526597 DOI: 10.1016/j.bcp.2022.115070  0.108
2013 Yu Y, Xu W, Wang J, Wang L, Yao W, Yang Y, Xu Y, Ma F, Du Y, Wang Y. The Chinese wild grapevine (Vitis pseudoreticulata) E3 ubiquitin ligase Erysiphe necator-induced RING finger protein 1 (EIRP1) activates plant defense responses by inducing proteolysis of the VpWRKY11 transcription factor. The New Phytologist. 200: 834-846. PMID 23905547 DOI: 10.1111/nph.12418  0.108
2021 Yang Y, Wang H, Li W, Wang X, Wei S, Liu Y, Xu Y. Prediction and analysis of multiple protein lysine modified sites based on conditional wasserstein generative adversarial networks. Bmc Bioinformatics. 22: 171. PMID 33789579 DOI: 10.1186/s12859-021-04101-y  0.108
2020 Wang R, Wang S, Xu Y, Yu X. Enhancing the thermostability of Rhizopus chinensis lipase by rational design and MD simulations. International Journal of Biological Macromolecules. PMID 32485250 DOI: 10.1016/j.ijbiomac.2020.05.243  0.108
2006 Yeung DK, Leung SW, Xu YC, Vanhoutte PM, Man RY. Puerarin, an isoflavonoid derived from Radix puerariae, potentiates endothelium-independent relaxation via the cyclic AMP pathway in porcine coronary artery. European Journal of Pharmacology. 552: 105-11. PMID 17027964 DOI: 10.1016/j.ejphar.2006.08.078  0.108
2021 Li JN, Du ZY, Li NF, Han YM, Zang TT, Yang MX, Liu XM, Wang JL, Mei H, Xu Y. Two three-dimensional polyanionic clusters [M(PMo)] (M = Co, Zn) exhibiting excellent photocatalytic CO reduction performance. Dalton Transactions (Cambridge, England : 2003). PMID 34115085 DOI: 10.1039/d1dt00809a  0.107
2015 Xu Y, Zhang R, Zhao J, Dong ZY, Wang D, Yang H, Wong KP. Assessing Short-Term Voltage Stability of Electric Power Systems by a Hierarchical Intelligent System. Ieee Transactions On Neural Networks and Learning Systems. PMID 26441430 DOI: 10.1109/Tnnls.2015.2441706  0.107
2017 Shu S, Xu Y, Xie L, Ouyang Y. The role of C/EBPβ phosphorylation in modulating membrane phospholipids repairing in LPS-induced human lung/bronchial epithelial cells. Gene. PMID 28760550 DOI: 10.1016/j.gene.2017.07.076  0.107
2015 Xu Y, Yan G, Ren Z, Dong G. Diverse sp(3) C-H functionalization through alcohol β-sulfonyloxylation. Nature Chemistry. 7: 829-34. PMID 26391083 DOI: 10.1038/Nchem.2326  0.107
2022 Zhao WH, Wang BY, Chen LJ, Fu WJ, Xu J, Liu J, Jin SW, Chen YX, Cao XM, Yang Y, Zhang YL, Wang FX, Zhang PY, Lei B, Gu LF, ... ... Xu Y, et al. Four-year follow-up of LCAR-B38M in relapsed or refractory multiple myeloma: a phase 1, single-arm, open-label, multicenter study in China (LEGEND-2). Journal of Hematology & Oncology. 15: 86. PMID 35794616 DOI: 10.1186/s13045-022-01301-8  0.107
2018 Luo XM, Chen L, Dong YY, Li J, Cui CH, Cao JP, Xu Y. Three new high-nuclear transition-metal-substituted heteropolytungstates: syntheses, crystal structures, magnetic studies and NLO properties. Dalton Transactions (Cambridge, England : 2003). PMID 29963671 DOI: 10.1039/C8Dt01613E  0.107
2020 Xu Y, Fulciniti M, Samur MK, Ho M, Deng S, Liu L, Wen K, Yu T, Chyra Z, Dereibal S, Zhang L, Yao Y, Chakraborty C, Morelli E, Li N, et al. YWHAE/14-3-3ε expression impacts the protein load contributing to proteasome inhibitor sensitivity in multiple myeloma. Blood. PMID 32187357 DOI: 10.1182/blood.2019004147  0.107
2024 Xu Y, Zhou Y, Yi X, Nie X. LRP8 promotes tumorigenesis in ovarian cancer through inhibiting p53 signaling. Cell Biology International. PMID 38263609 DOI: 10.1002/cbin.12133  0.107
2018 Zhang M, Xu Y, Li L, Liu Z, Yang X, Yu DJ. Accurate RNA 5-methylcytosine site prediction based on heuristic physical-chemical properties reduction and classifier ensemble. Analytical Biochemistry. PMID 29649472 DOI: 10.1016/j.ab.2018.03.027  0.107
2013 Gordon MS, Rosen LS, Mendelson D, Ramanathan RK, Goldman J, Liu L, Xu Y, Gerson SL, Anthony SP, Figg WD, Spencer S, Adams BJ, Theuer CP, Leigh BR, Weiss GJ. A phase 1 study of TRC102, an inhibitor of base excision repair, and pemetrexed in patients with advanced solid tumors. Investigational New Drugs. 31: 714-23. PMID 23054206 DOI: 10.1007/S10637-012-9876-9  0.106
2016 Shen W, Ren X, Zhu J, Xu Y, Lin J, Li Y, Zhao F, Zheng H, Li R, Cui X, Zhang X, Lu X, Zheng Z. Discovery of a new structural class of competitive hDHODH inhibitors with in vitro and in vivo anti-inflammatory, immunosuppressive effects. European Journal of Pharmacology. PMID 27597161 DOI: 10.1016/j.ejphar.2016.09.004  0.106
2014 Zhang R, Wu Q, Xu Y. Lichenysin, a cyclooctapeptide occurring in Chinese liquor jiannanchun reduced the headspace concentration of phenolic off-flavors via hydrogen-bond interactions. Journal of Agricultural and Food Chemistry. 62: 8302-7. PMID 25065507 DOI: 10.1021/jf502053g  0.106
2019 Li X, Jiao W, Zhang W, Xu Y, Cao J, Jiang W. Characterizing the interactions of dietary condensed tannins with bile salts. Journal of Agricultural and Food Chemistry. PMID 31379164 DOI: 10.1021/acs.jafc.9b03985  0.105
2018 Xu Y, Yang Y, Wang Z, Li C, Shao Y. A systematic review on posttranslational modification in proteins: feature construction, algorithm and webserver. Protein and Peptide Letters. PMID 30255739 DOI: 10.2174/0929866525666180925151720  0.105
2011 Xu W, Yu Y, Zhou Q, Ding J, Dai L, Xie X, Xu Y, Zhang C, Wang Y. Expression pattern, genomic structure, and promoter analysis of the gene encoding stilbene synthase from Chinese wild Vitis pseudoreticulata. Journal of Experimental Botany. 62: 2745-61. PMID 21504880 DOI: 10.1093/jxb/erq447  0.105
2021 Li T, Cheng X, Wang X, Li G, Wang B, Wang W, Zhang N, Han Y, Jiao B, Wang Y, Liu G, Xu T, Xu Y. GLYI-4 functions downstream of NAC72 to modulate downy mildew resistance in grapevine. The Plant Journal : For Cell and Molecular Biology. PMID 34318550 DOI: 10.1111/tpj.15447  0.105
2018 Liu X, Xu Y. HnRNPA1 Specifically Recognizes the Base of Nucleotide at the Loop of RNA G-Quadruplex. Molecules (Basel, Switzerland). 23. PMID 29361764 DOI: 10.3390/molecules23010237  0.105
2002 Shi Y, Li L, Li Y, Xu Y, Chen X, Xue Z, You X. Syntheses and structures of two- and one-dimensional organic–inorganic hybrid compounds assembled from PbI2 and 1,4-bis(4-pyridyl)-2,3-diaza-1,3-butadiene Inorganic Chemistry Communications. 5: 1090-1094. DOI: 10.1016/S1387-7003(02)00669-X  0.105
2017 Xu Y, Luo Z, Li S, Li W, Zhang X, Zuo YY, Huang F, Yue T. Perturbation of the pulmonary surfactant monolayer by single-walled carbon nanotubes: a molecular dynamics study. Nanoscale. PMID 28485435 DOI: 10.1039/C7Nr00890B  0.105
2016 Xu H, Lu H, Xu Z, Luan L, Li C, Xu Y, Dong K, Zhang J, Li X, Li Y, Liu G, Gong S, Zhao YG, Liu A, Zhang Y, et al. Discovery of CNS Penetrant CXCR2 Antagonists for the Potential Treatment of CNS Demyelinating Disorders. Acs Medicinal Chemistry Letters. 7: 397-402. PMID 27096048 DOI: 10.1021/acsmedchemlett.5b00489  0.105
2019 Li J, Jia M, Chen G, Nie S, Zheng C, Zeng W, Xu Y, Wang C, Cao X, Liu Q. Involvement of p38 Mitogen-Activated Protein Kinase in Altered Expressions of AQP1 and AQP4 after Carbon Monoxide Poisoning in Rat Astrocytes. Basic & Clinical Pharmacology & Toxicology. PMID 31063681 DOI: 10.1111/bcpt.13247  0.105
2023 Bao Y, Xu Y, Jia F, Li M, Xu R, Zhang F, Guo J. Allosteric Inhibition of Myosin by Phenamacril: A Synergistic Mechanism Revealed by Computational and Experimental Approaches. Pest Management Science. PMID 37540764 DOI: 10.1002/ps.7699  0.105
2016 Yue T, Xu Y, Li S, Zhang X, Huang F. Lipid extraction mediates aggregation of carbon nanospheres in pulmonary surfactant monolayers. Physical Chemistry Chemical Physics : Pccp. PMID 27353041 DOI: 10.1039/C6Cp01957A  0.104
2016 Xu Y, Shang Y, Ye A. Dynamic interaction between bridge pier and its large pile foundation considering earthquake and scour depths Advances in Structural Engineering. 19: 1390-1402. DOI: 10.1177/1369433216642077  0.104
2012 Zhang S, Chang Z, Li Z, DuanMu H, Li Z, Li K, Liu Y, Qiu F, Xu Y. Calculating phenotypic similarity between genes using hierarchical structure data based on semantic similarity. Gene. 497: 58-65. PMID 22305981 DOI: 10.1016/j.gene.2012.01.014  0.104
2017 Liu X, Ishizuka T, Bao HL, Wada K, Takada Y, Iida K, Nagasawa K, Yang D, Xu Y. Structure-dependent binding of hnRNP A1 to telomere RNA. Journal of the American Chemical Society. PMID 28510424 DOI: 10.1021/jacs.7b01599  0.104
2023 Xiao CD, Jia MH, Zhong MQ, Xu Y, Yu ZT, He ZY, Lu X, Zhang Y, Zhou X, Fu LY, Shen XC. Unveiling the role of G-quadruplex structure in promoter region: Regulation of ABCA1 expression in macrophages possibly via NONO protein recruitment. International Journal of Biological Macromolecules. 125443. PMID 37353131 DOI: 10.1016/j.ijbiomac.2023.125443  0.104
2015 Xu Y, Ding YX, Ding J, Lei YH, Wu LY, Deng NY. iSuc-PseAAC: predicting lysine succinylation in proteins by incorporating peptide position-specific propensity. Scientific Reports. 5: 10184. PMID 26084794 DOI: 10.1038/srep10184  0.104
2021 Bi J, Jing X, Wu L, Zhou X, Gu J, Nie Y, Xu Y. Computational design of noncanonical amino acid-based thioether staples at N/C-terminal domains of multi-modular pullulanase for thermostabilization in enzyme catalysis. Computational and Structural Biotechnology Journal. 19: 577-585. PMID 33510863 DOI: 10.1016/j.csbj.2020.12.043  0.104
2023 Xu Y. Surface morphology and microstructure of Bauhinia variegata L. flowers and leaves. Micron (Oxford, England : 1993). 177: 103575. PMID 38086225 DOI: 10.1016/j.micron.2023.103575  0.103
2020 Tan Y, Xu Y, Cheng C, Zheng C, Zeng W, Wang J, Zhang X, Yang X, Wang J, Yang X, Nie S, Cao X. LY354740 Reduces Extracellular Glutamate Concentration, Inhibits Phosphorylation of Fyn/NMDARs, and Expression of PLK2/pS129 α-Synuclein in Mice Treated With Acute or Sub-Acute MPTP. Frontiers in Pharmacology. 11: 183. PMID 32180729 DOI: 10.3389/fphar.2020.00183  0.103
2023 Xiao CD, Zhong MQ, Gao Y, Yang ZL, Jia MH, Hu XH, Xu Y, Shen XC. A Unique G-Quadruplex Aptamer: A Novel Approach for Cancer Cell Recognition, Cell Membrane Visualization, and RSV Infection Detection. International Journal of Molecular Sciences. 24. PMID 37762645 DOI: 10.3390/ijms241814344  0.103
2007 Lu Y, Xu Y, Li Y, Wang E, Xu X, Ma Y. New polyoxometalate compounds built up of lacunary Wells-Dawson anions and trivalent lanthanide cations. Inorganic Chemistry. 45: 2055-60. PMID 16499366 DOI: 10.1021/IC0515857  0.103
2017 Liu K, Dong L, Xu Y, Yan X, Li F, Lu Y, Tao W, Peng H, Wu Y, Su Y, Ling D, He T, Qian H, Yu SH. Stable gadolinium based nanoscale lyophilized injection for enhanced MR angiography with efficient renal clearance. Biomaterials. 158: 74-85. PMID 29304404 DOI: 10.1016/J.Biomaterials.2017.12.023  0.103
2021 Zhang X, Kang R, Liu Y, Yan Z, Xu Y, Yue T. From reversible to irreversible: When the membrane nanotube pearling is coupled with phase separation. Colloids and Surfaces. B, Biointerfaces. 209: 112160. PMID 34736219 DOI: 10.1016/j.colsurfb.2021.112160  0.103
2018 Xu Y, Yuan T, Nour HF, Fang L, Olson MA. Bis-Bipyridinium Gemini Surfactant-Based Supramolecular Helical Fibers and Solid State Thermochromism. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30168870 DOI: 10.1002/Chem.201803496  0.103
2020 Cheng Y, Shan K, Xu Y, Yang J, He J, Jiang J. Hardware implementation of photoelectrically modulated dendritic arithmetic and spike-timing-dependent plasticity enabled by an ion-coupling gate-tunable vertical 0D-perovskite/2D-MoS hybrid-dimensional van der Waals heterostructure. Nanoscale. PMID 33103690 DOI: 10.1039/d0nr04950f  0.103
2008 Dong M, Bridges JP, Apsley K, Xu Y, Weaver TE. ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C. Molecular Biology of the Cell. 19: 2620-30. PMID 18400946 DOI: 10.1091/mbc.e07-07-0674  0.103
2016 Chen C, Liang H, Liao X, Pan J, Chen J, Zhao S, Xu Y, Wu Y, Ni J. A humanized chimeric antibody Hai178 targeted to the β subunit of F1F0 ATP synthase. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. PMID 27704358 DOI: 10.1007/s13277-016-5423-1  0.103
2022 Yang X, Wang J, Zeng W, Zhang X, Yang X, Xu Y, Xu Y, Cao X. Time-dependent alterations in the rat nigrostriatal system after intrastriatal injection of fibrils formed by α-Syn and tau fragments. Frontiers in Aging Neuroscience. 14: 1049418. PMID 36518823 DOI: 10.3389/fnagi.2022.1049418  0.102
2022 Yang S, Fan W, Nie Y, Xu Y. The formation and structural characteristics of melanoidins from fermenting and distilled grains of Chinese liquor (baijiu). Food Chemistry. 410: 135372. PMID 36634563 DOI: 10.1016/j.foodchem.2022.135372  0.102
2020 Xu Y, Hu J, Yilmaz DE, Bachmann S. Connexin 43 is differentially distributed within renal vasculature and mediates profibrotic differentiation in medullary fibroblasts. American Journal of Physiology. Renal Physiology. PMID 33196322 DOI: 10.1152/ajprenal.00453.2020  0.102
2019 Liu J, Xu Y, Liu Z, Ren H, Meng Z, Liu K, Liu Z, Yong J, Wang Y, Li X. A modified hydrophobic ion-pairing complex strategy for long-term peptide delivery with high drug encapsulation and reduced burst release from PLGA microspheres. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 31563632 DOI: 10.1016/j.ejpb.2019.09.022  0.102
2024 Wang J, Gu C, Xu Y, Zou W. Discontinuous phase transition switching induced by a power-law function between dynamical parameters in coupled oscillators. Chaos (Woodbury, N.Y.). 34. PMID 38341760 DOI: 10.1063/5.0189672  0.102
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