2005 — 2007 |
Roberts, Reade B |
F32Activity Code Description: To provide postdoctoral research training to individuals to broaden their scientific background and extend their potential for research in specified health-related areas. |
Characterization of the Cichlid Orange Blotch Mutant @ University of New Hampshire
DESCRIPTION (provided by applicant): Regenerative therapy utilizing pluripotent stem cells holds promise for treatment of a variety of pathological conditions. However, the mechanisms that determine the growth, patterning, and homeostasis of tissue from progenitor cells during development versus those involved in tissue regeneration in an adult organism remain largely unknown. Pigment pattern in fishes represents an attractive model system to directly visualize mechanisms of patterning in adults, since fish undergo larval to adult metamorphosis that involves changes in growth and organization of pigment cell populations, and the capacity to regenerate fins permits examination of pigment cell biology during tissue regeneration. The proposed research aims to characterize the naturally occurring cichlid fish orange blotch mutant. Pigment cell migration and differentiation will be comparatively analyzed during adult development and regeneration using spatial and temporal analysis, as well as in situ-based characterization of differentiation state with lineage markers. Also, the orange blotch gene will be identified within the previously mapped interval using a directed mapping approach and candidate gene analysis.
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0.948 |
2019 — 2021 |
Roberts, Reade B Thomson, Margareta Maria |
R25Activity Code Description: For support to develop and/or implement a program as it relates to a category in one or more of the areas of education, information, training, technical assistance, coordination, or evaluation. |
Environmental Health Research Experiences For Teachers in High-Poverty Schools: a Professional Developmentprogram @ North Carolina State University Raleigh
Abstract The current project proposes an innovative professional development (PD) program in environmental health research experiences for science high-school teachers from schools with high poverty levels in North Carolina. In a collaborative effort, experts from the College of Education and scientists affiliated with the Center for Human Health and Environment (CHHE), and the Comparative Medicine Institute (CMI) at NC State University will provide teachers (N=40) with unique authentic lab experiences. The 8-week summer research PD program aims at enhancing teachers' environmental health literacy and research skills that will support novel science teaching strategies. The specific aims addressed by the program are the following: 1) to provide teachers with a practical understanding of the scientific method in mentored research projects examining links between environmental stressors and health; 2) to provide teachers with an understanding of core conceptual issues in toxicology; 3) to train teachers in ethical issues in scientific conduct, science communication, and public health; 4) to immerse teachers in authentic research lab experiences by using a cognitive apprenticeship model; and 5) to develop a comprehensive evaluation plan in order to assess the short- and long- term PD outcomes. In the proposed environmental health science (EHS) research PD program, teachers will be integrated into genuine research projects and attend lab meetings, gaining general knowledge of how research is conducted and specialized knowledge related to ongoing projects in their host lab. Additionally, teachers in the program will come together one day per week in a workshop environment, to share their diversity of research experiences and gain additional training in biological concepts and ethical issues related to environmental health sciences.
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0.948 |