Christina H. Eng, Ph.D.
Affiliations: | 2006 | Pfizer, Inc., San Diego, CA, United States |
Area:
Microtubules, Actin, Cell migration, Cell polarityGoogle:
"Christina Eng"Parents
Sign in to add mentor| Gregg G. Gundersen | grad student | 2006 | Columbia | |
| (Regulation of microtubule stabilization by the formin mDia and GSK3beta.) | ||||
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Publications
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| Arensman MD, Yang XS, Zhong W, et al. (2020) Anti-tumor immunity influences cancer cell reliance upon ATG7. Oncoimmunology. 9: 1800162 |
| Arensman MD, Eng CH. (2018) Self-Digestion for Lifespan Extension: Enhanced Autophagy Delays Aging. Molecular Cell. 71: 485-486 |
| Nyfeler B, Eng CH. (2016) Revisiting autophagy addiction of tumor cells. Autophagy. 0 |
| Eng CH, Wang Z, Tkach D, et al. (2015) Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy. Proceedings of the National Academy of Sciences of the United States of America |
| Eng CH, Abraham RT. (2011) The autophagy conundrum in cancer: influence of tumorigenic metabolic reprogramming. Oncogene. 30: 4687-96 |
| Eng CH, Abraham RT. (2010) Glutaminolysis yields a metabolic by-product that stimulates autophagy. Autophagy. 6: 968-70 |
| Eng CH, Yu K, Lucas J, et al. (2010) Ammonia derived from glutaminolysis is a diffusible regulator of autophagy. Science Signaling. 3: ra31 |
| Abraham RT, Eng CH. (2008) Mammalian target of rapamycin as a therapeutic target in oncology. Expert Opinion On Therapeutic Targets. 12: 209-22 |
| Eng CH, Huckaba TM, Gundersen GG. (2006) The formin mDia regulates GSK3beta through novel PKCs to promote microtubule stabilization but not MTOC reorientation in migrating fibroblasts. Molecular Biology of the Cell. 17: 5004-16 |
| Gundersen GG, Wen Y, Eng CH, et al. (2005) Regulation of microtubules by Rho GTPases in migrating cells. Novartis Foundation Symposium. 269: 106-16; discussion 1 |