Samuel B. Stephens, Ph.D.

Affiliations: 
2007 Duke University, Durham, NC 
Area:
Secretion, mRNA-ER association
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"Samuel Stephens"

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Christopher Nicchitta grad student 2007 Duke
 (Harnessing the power of translation: Selective advantages in mRNA translation by endoplasmic reticulum-bound ribosomes.)
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Publications

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Li M, Shao F, Qian Q, et al. (2021) A putative long noncoding RNA-encoded micropeptide maintains cellular homeostasis in pancreatic β cells. Molecular Therapy. Nucleic Acids. 26: 307-320
Hohmeier HE, Zhang L, Taylor B, et al. (2020) Identification of a small molecule that stimulates human β-cell proliferation and insulin secretion, and protects against cytotoxic stress in rat insulinoma cells. Plos One. 15: e0224344
Hayes HL, Peterson BS, Haldeman JM, et al. (2017) Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival. Plos One. 12: e0172567
Tessem JS, Moss LG, Chao LC, et al. (2014) Nkx6.1 regulates islet β-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors. Proceedings of the National Academy of Sciences of the United States of America. 111: 5242-7
Stephens SB, Dodd RD, Lerner RS, et al. (2008) Analysis of mRNA partitioning between the cytosol and endoplasmic reticulum compartments of mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 419: 197-214
Stephens SB, Nicchitta CV. (2008) Divergent regulation of protein synthesis in the cytosol and endoplasmic reticulum compartments of mammalian cells. Molecular Biology of the Cell. 19: 623-32
Stephens SB, Nicchitta CV. (2007) In vitro and tissue culture methods for analysis of translation initiation on the endoplasmic reticulum. Methods in Enzymology. 431: 47-60
Nicchitta CV, Lerner RS, Stephens SB, et al. (2005) Pathways for compartmentalizing protein synthesis in eukaryotic cells: the template-partitioning model. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 83: 687-95
Stephens SB, Dodd RD, Brewer JW, et al. (2005) Stable ribosome binding to the endoplasmic reticulum enables compartment-specific regulation of mRNA translation. Molecular Biology of the Cell. 16: 5819-31
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