Jeremiah W. Hanes, Ph.D.

Affiliations: 
2004 University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Cellular and Molecular Biology
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"Jeremiah Hanes"

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Kenneth A. Johnson grad student 2004 UT Austin
 (The role of the human mitochondrial polymerase in the toxicity of nucleoside analogs and aging.)
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Rodrigues MJ, Windeisen V, Zhang Y, et al. (2017) Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis. Nature Chemical Biology
Mehta AP, Hanes JW, Abdelwahed SH, et al. (2013) Catalysis of a new ribose carbon-insertion reaction by the molybdenum cofactor biosynthetic enzyme MoaA. Biochemistry. 52: 1134-6
Bale S, Brooks W, Hanes JW, et al. (2009) Role of the sulfonium center in determining the ligand specificity of human s-adenosylmethionine decarboxylase. Biochemistry. 48: 6423-30
Burton RL, Hanes JW, Grant GA. (2008) A stopped flow transient kinetic analysis of substrate binding and catalysis in Escherichia coli D-3-phosphoglycerate dehydrogenase. The Journal of Biological Chemistry. 283: 29706-14
Hanes JW, Keresztes I, Begley TP. (2008) 13C NMR snapshots of the complex reaction coordinate of pyridoxal phosphate synthase. Nature Chemical Biology. 4: 425-30
Hanes JW, Burns KE, Hilmey DG, et al. (2008) Mechanistic studies on pyridoxal phosphate synthase: the reaction pathway leading to a chromophoric intermediate. Journal of the American Chemical Society. 130: 3043-52
Hanes JW, Johnson KA. (2008) Exonuclease removal of dideoxycytidine (zalcitabine) by the human mitochondrial DNA polymerase. Antimicrobial Agents and Chemotherapy. 52: 253-8
Hanes JW, Johnson KA. (2008) Real-time measurement of pyrophosphate release kinetics. Analytical Biochemistry. 372: 125-7
Hanes JW, Johnson KA. (2007) A novel mechanism of selectivity against AZT by the human mitochondrial DNA polymerase. Nucleic Acids Research. 35: 6973-83
Hanes JW, Zhu Y, Parris DS, et al. (2007) Enzymatic therapeutic index of acyclovir. Viral versus human polymerase gamma specificity. The Journal of Biological Chemistry. 282: 25159-67
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