Brian J. Yeh, Ph.D.

2007 Chemistry and Chemical Biology University of California, San Francisco, San Francisco, CA 
Cellular Signaling Systems
"Brian Yeh"


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Wendell A. Lim grad student 2007 UCSF
 (Construction of synthetic signaling circuits by modular recombination.)
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Gógl G, Schneider KD, Yeh BJ, et al. (2015) The Structure of an NDR/LATS Kinase-Mob Complex Reveals a Novel Kinase-Coactivator System and Substrate Docking Mechanism. Plos Biology. 13: e1002146
Gógl G, Schneider KD, Yeh BJ, et al. (2015) Molecular analysis of Cbk1 docking peptides in Ace2 and Ssd1 highlights importance of a [YF]xFP motif. Plos Biology
Nguyen Ba AN, Yeh BJ, van Dyk D, et al. (2012) Proteome-wide discovery of evolutionary conserved sequences in disordered regions. Science Signaling. 5: rs1
Kapp GT, Liu S, Stein A, et al. (2012) Control of protein signaling using a computationally designed GTPase/GEF orthogonal pair. Proceedings of the National Academy of Sciences of the United States of America. 109: 5277-82
Yadav SS, Yeh BJ, Craddock BP, et al. (2009) Reengineering the signaling properties of a Src family kinase. Biochemistry. 48: 10956-62
Mazanka E, Alexander J, Yeh BJ, et al. (2008) The NDR/LATS family kinase Cbk1 directly controls transcriptional asymmetry. Plos Biology. 6: e203
Yeh BJ, Lim WA. (2007) Synthetic biology: lessons from the history of synthetic organic chemistry. Nature Chemical Biology. 3: 521-5
Yeh BJ, Rutigliano RJ, Deb A, et al. (2007) Rewiring cellular morphology pathways with synthetic guanine nucleotide exchange factors. Nature. 447: 596-600
Sallee NA, Yeh BJ, Lim WA. (2007) Engineering modular protein interaction switches by sequence overlap. Journal of the American Chemical Society. 129: 4606-11
Bhattacharyya RP, Reményi A, Yeh BJ, et al. (2006) Domains, motifs, and scaffolds: the role of modular interactions in the evolution and wiring of cell signaling circuits. Annual Review of Biochemistry. 75: 655-80
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