William G. Fairbrother
Affiliations: | Molecular Biology, Cell Biology and Biochemistry | Brown University, Providence, RI |
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"William Fairbrother"
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| Shin J, Fredericks AM, Armstead BE, et al. (2025) Predicting Nonsense-mediated mRNA Decay from Splicing Events in Sepsis using RNA-Sequencing Data. Medrxiv : the Preprint Server For Health Sciences |
| Duan C, Rong S, Buerer L, et al. (2024) One-Size-Fits-Many: Antisense oligonucleotides for rescuing splicing mutations in hotspot exons. Biorxiv : the Preprint Server For Biology |
| Buerer L, Clark NE, Welch A, et al. (2024) The debranching enzyme Dbr1 regulates lariat turnover and intron splicing. Nature Communications. 15: 4617 |
| Buerer L, Clark N, Welch A, et al. (2023) The debranching enzyme Dbr1 regulates lariat turnover and intron splicing. Research Square |
| Townley BA, Buerer L, Tsao N, et al. (2023) A functional link between lariat debranching enzyme and the intron-binding complex is defective in non-photosensitive trichothiodystrophy. Molecular Cell |
| Rong S, Neil CR, Welch A, et al. (2023) Large-scale functional screen identifies genetic variants with splicing effects in modern and archaic humans. Proceedings of the National Academy of Sciences of the United States of America. 120: e2218308120 |
| Fredericks AM, East KW, Shi Y, et al. (2022) Identification and mechanistic basis of non-ACE2 blocking neutralizing antibodies from COVID-19 patients with deep RNA sequencing and molecular dynamics simulations. Frontiers in Molecular Biosciences. 9: 1080964 |
| Rhine CL, Neil C, Wang J, et al. (2022) Massively parallel reporter assays discover de novo exonic splicing mutants in paralogs of Autism genes. Plos Genetics. 18: e1009884 |
| Glidden DT, Buerer JL, Saueressig CF, et al. (2021) Hotspot exons are common targets of splicing perturbations. Nature Communications. 12: 2756 |
| Rong S, Buerer L, Rhine CL, et al. (2020) Mutational bias and the protein code shape the evolution of splicing enhancers. Nature Communications. 11: 2845 |