Shankar Varadarajan, Ph.D.
Affiliations: | 2008 | Molecular, Cell and Developmental Biology | University of Texas at Austin, Austin, Texas, U.S.A. |
Area:
Cell Biology, Molecular BiologyGoogle:
"Shankar Varadarajan"Parents
Sign in to add mentor| Shawn B. Bratton | grad student | 2008 | UT Austin | |
| (p38 MAPKs coordinately regulate distinct phases of autophagy and lysosomal biogenesis.) | ||||
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Publications
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| Wible DJ, Parikh Z, Cho EJ, et al. (2024) Unexpected inhibition of the lipid kinase PIKfyve reveals an epistatic role for p38 MAPKs in endolysosomal fission and volume control. Cell Death & Disease. 15: 80 |
| Wible DJ, Parikh Z, Cho EJ, et al. (2023) Unexpected inhibition of the lipid kinase PIKfyve reveals an epistatic role for p38 MAPKs in endolysosomal fission and volume control. Biorxiv : the Preprint Server For Biology |
| Carter RJ, Milani M, Beckett AJ, et al. (2022) Novel roles of RTN4 and CLIMP-63 in regulating mitochondrial structure, bioenergetics and apoptosis. Cell Death & Disease. 13: 436 |
| Carter RJ, Milani M, Butterworth M, et al. (2019) Exploring the potential of BH3 mimetic therapy in squamous cell carcinoma of the head and neck. Cell Death & Disease. 10: 912 |
| Milani M, Beckett AJ, Al-Zebeeby A, et al. (2019) DRP-1 functions independently of mitochondrial structural perturbations to facilitate BH3 mimetic-mediated apoptosis. Cell Death Discovery. 5: 117 |
| Yedida G, Milani M, Cohen GM, et al. (2019) Apogossypol-mediated reorganisation of the endoplasmic reticulum antagonises mitochondrial fission and apoptosis. Cell Death & Disease. 10: 521 |
| Al-Zebeeby A, Vogler M, Milani M, et al. (2018) Targeting intermediary metabolism enhances the efficacy of BH3 mimetic therapy in haematological malignancies. Haematologica |
| Greaves G, Milani M, Butterworth M, et al. (2018) BH3-only proteins are dispensable for apoptosis induced by pharmacological inhibition of both MCL-1 and BCL-X. Cell Death and Differentiation |
| Henz K, Al-Zebeeby A, Basoglu M, et al. (2018) Selective BH3-mimetics targeting BCL-2, BCL-XL or MCL-1 induce severe mitochondrial perturbations. Biological Chemistry |
| Milani M, Byrne DP, Greaves G, et al. (2017) DRP-1 is required for BH3 mimetic-mediated mitochondrial fragmentation and apoptosis. Cell Death & Disease. 8: e2552 |