Alyson K. Freeman, Ph.D.

Affiliations: 
2010 University of South Florida, Tampa, FL, United States 
Area:
Molecular Biology
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"Alyson Freeman"

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Alvaro Monteiro grad student 2010 University of South Florida
 (CHK2 is negatively regulated by protein phosphatase 2A.)
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Publications

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Crowe MS, Zavorotinskaya T, Voliva CF, et al. (2021) RAF-mutant melanomas differentially depend on ERK2 over ERK1 to support aberrant MAPK pathway activation and cell proliferation. Molecular Cancer Research : McR
Leung GP, Feng T, Sigoillot FD, et al. (2018) Hyperactivation of MAPK Signaling is Deleterious to RAS/RAF Mutant Melanoma. Molecular Cancer Research : McR
Leung GP, Feng T, Shirley MD, et al. (2018) Abstract 965: Deleterious effects of MAPK pathway hyperactivation in BRAF-mutant melanoma Cancer Research. 78: 965-965
Emery CM, Monaco KA, Wang P, et al. (2017) BRAF-inhibitor associated MEK Mutations Increase RAF-dependent and-independent Enzymatic Activity. Molecular Cancer Research : McR
Freeman AK, Ritt DA, Morrison DK. (2013) The importance of Raf dimerization in cell signaling. Small Gtpases. 4: 180-5
Freeman AK, Ritt DA, Morrison DK. (2013) Effects of Raf dimerization and its inhibition on normal and disease-associated Raf signaling. Molecular Cell. 49: 751-8
Freeman AK, Ritt DA, Morrison DK. (2012) Abstract 1239: Differential effects of dimerization on B-Raf and C-Raf function revealed by mutational analysis and peptide inhibitors that target the Raf dimer interface Cancer Research. 72: 1239-1239
McKay MM, Freeman AK, Morrison DK. (2011) Complexity in KSR function revealed by Raf inhibitor and KSR structure studies. Small Gtpases. 2: 276-281
Freeman AK, Morrison DK. (2011) 14-3-3 Proteins: diverse functions in cell proliferation and cancer progression. Seminars in Cell & Developmental Biology. 22: 681-7
Freeman AK, Monteiro AN. (2010) Phosphatases in the cellular response to DNA damage. Cell Communication and Signaling : Ccs. 8: 27
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