David Givol

Affiliations: 
MCB Molecular Cell Biology Weizmann Institute of Science, Rehovot, Israel 
Area:
Molecular Biology, Cell Biology, Oncology
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"David Givol"
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Publications

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Amsterdam A, Raanan C, Polin N, et al. (2014) Modulation of c-kit expression in pancreatic adenocarcinoma: a novel stem cell marker responsible for the progression of the disease. Acta Histochemica. 116: 197-203
Amsterdam A, Raanan C, Schreiber L, et al. (2013) Differential localization of LGR5 and Nanog in clusters of colon cancer stem cells. Acta Histochemica. 115: 320-9
Amsterdam A, Raanan C, Schreiber L, et al. (2013) Localization of the stem cell markers LGR5 and Nanog in the normal and the cancerous human ovary and their inter-relationship. Acta Histochemica. 115: 330-8
D'Orazi G, Givol D. (2012) p53 reactivation: the link to zinc. Cell Cycle (Georgetown, Tex.). 11: 2581-2
Margalit O, Simon AJ, Yakubov E, et al. (2012) Zinc supplementation augments in vivo antitumor effect of chemotherapy by restoring p53 function. International Journal of Cancer. Journal International Du Cancer. 131: E562-8
Sheffer M, Simon AJ, Jacob-Hirsch J, et al. (2011) Genome-wide analysis discloses reversal of the hypoxia-induced changes of gene expression in colon cancer cells by zinc supplementation. Oncotarget. 2: 1191-202
Puca R, Nardinocchi L, Porru M, et al. (2011) Restoring p53 active conformation by zinc increases the response of mutant p53 tumor cells to anticancer drugs. Cell Cycle (Georgetown, Tex.). 10: 1679-89
Nardinocchi L, Pantisano V, Puca R, et al. (2010) Zinc downregulates HIF-1α and inhibits its activity in tumor cells in vitro and in vivo. Plos One. 5: e15048
Nardinocchi L, Puca R, Givol D, et al. (2010) Counteracting MDM2-induced HIPK2 downregulation restores HIPK2/p53 apoptotic signaling in cancer cells. Febs Letters. 584: 4253-8
Puca R, Nardinocchi L, Givol D, et al. (2010) Regulation of p53 activity by HIPK2: Molecular mechanisms and therapeutical implications in human cancer cells Oncogene. 29: 4378-4387
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