Christopher W. Knouff, Ph.D.
Affiliations: | 2000 | University of North Carolina, Chapel Hill, Chapel Hill, NC |
Area:
Genetics, Molecular Biology, Animal Physiology BiologyGoogle:
"Christopher Knouff"Parents
Sign in to add mentor| Nobuyo Maeda | grad student | 2000 | UNC Chapel Hill | |
| (Lipoprotein clearance in mouse models of the apolipoprotein E polymorphism.) | ||||
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Publications
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| Assimes TL, Hólm H, Kathiresan S, et al. (2010) Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. Journal of the American College of Cardiology. 56: 1552-63 |
| Knouff C, Auwerx J. (2005) Peroxisome proliferator-activated receptor-gamma calls for activation in moderation: lessons from genetics and pharmacology. Endocrine Reviews. 25: 899-918 |
| Knouff C, Briand O, Lestavel S, et al. (2004) Defective VLDL metabolism and severe atherosclerosis in mice expressing human apolipoprotein E isoforms but lacking the LDL receptor. Biochimica Et Biophysica Acta. 1684: 8-17 |
| Malloy SI, Altenburg MK, Knouff C, et al. (2004) Harmful effects of increased LDLR expression in mice with human APOE*4 but not APOE*3. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 91-7 |
| Altenburg MK, Malloy SI, Knouff C, et al. (2004) ApoE4 trapping by the low density lipoprotein receptor International Congress Series. 1262: 388-391 |
| Knouff C, Malloy S, Wilder J, et al. (2001) Doubling expression of the low density lipoprotein receptor by truncation of the 3'-untranslated region sequence ameliorates type iii hyperlipoproteinemia in mice expressing the human apoe2 isoform. The Journal of Biological Chemistry. 276: 3856-62 |
| Knouff C, Hinsdale ME, Mezdour H, et al. (1999) Apo E structure determines VLDL clearance and atherosclerosis risk in mice. The Journal of Clinical Investigation. 103: 1579-86 |
| Sullivan PM, Mezdour H, Aratani Y, et al. (1997) Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis Journal of Biological Chemistry. 272: 17972-17980 |