Jason W. Botten, Ph.D.

Affiliations: 
2000 University of New Mexico, Albuquerque, NM, United States 
Area:
Molecular Biology, Ecology Biology, Zoology Biology
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"Jason Botten"

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Brian Hjelle grad student 2000 Univ. of New Mexico
 (Experimental infection model for sin nombre hantavirus in the deer mouse (Peromyscus maniculatus): A novel approach yields first insights on the host -pathogen interaction.)
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Publications

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Guo H, Cho B, Hinton PR, et al. (2023) An ACE2 decamer viral trap as a durable intervention solution for current and future SARS-CoV. Emerging Microbes & Infections. 12: 2275598
Bruce EA, Mills MG, Sampoleo R, et al. (2021) Predicting Infectivity: Comparing Four PCR-based Assays to Detect Culturable SARS-CoV-2 in Clinical Samples. Embo Molecular Medicine. e15290
Victor J, Deutsch J, Whitaker A, et al. (2021) SARS-CoV-2 triggers DNA damage response in Vero E6 cells. Biochemical and Biophysical Research Communications. 579: 141-145
Rissanen I, Krumm SA, Stass R, et al. (2021) Structural Basis for a Neutralizing Antibody Response Elicited by a Recombinant Hantaan Virus Gn Immunogen. Mbio. e0253120
Ziegler CM, Botten JW. (2020) Defective Interfering Particles of Negative-Strand RNA Viruses. Trends in Microbiology. 28: 554-565
King BR, Samacoits A, Eisenhauer PL, et al. (2018) Visualization of arenavirus RNA species in individual cells by single-molecule fluorescence in situ hybridization (smFISH) suggests a model of cyclical infection and clearance during persistence. Journal of Virology
Ziegler CM, Bruce EA, Kelly JA, et al. (2018) The use of novel epitope-tagged arenaviruses reveals that Rab5c-positive endosomal membranes are targeted by the LCMV matrix protein. The Journal of General Virology. 99: 187-193
King BR, Kellner S, Eisenhauer PL, et al. (2017) Visualization of the lymphocytic choriomeningitis mammarenavirus (LCMV) genome reveals the early endosome as a possible site for genome replication and viral particle pre-assembly. The Journal of General Virology
King BR, Hershkowitz D, Eisenhauer PL, et al. (2017) A map of the arenavirus nucleoprotein-host protein interactome reveals that Junín virus selectively impairs the antiviral activity of PKR. Journal of Virology
Klaus JP, Botten J. (2016) Highly Sensitive Assay for Measurement of Arenavirus-cell Attachment. Journal of Visualized Experiments : Jove. e53682
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