Michael G. Kearse, Ph.D.
Affiliations: | 2013 | Molecular Biology | Lehigh University, Bethlehem, PA, United States |
Area:
Molecular Biology, Cell Biology, Biochemistry, GeneticsGoogle:
"Michael Kearse"Parents
Sign in to add mentor| Vassie C. Ware | grad student | 2013 | Lehigh University | |
| (Characterization of the Ribosomal Protein L22e Family in Drosophila melanogaster: Evidence for Functional Diversification of Duplicated Ribosomal Protein Genes.) | ||||
| Peter Todd | post-doc | Ohio State (Neurotree) | ||
| Jeremy E Wilusz | post-doc | 2016-2019 | University of Pennsylvania Perelman School of Medicine | |
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Publications
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| Scarpitti MR, Pastore B, Tang W, et al. (2024) Characterization of ribosome stalling and no-go mRNA decay stimulated by the Fragile X protein, FMRP. The Journal of Biological Chemistry. 107540 |
| Anastas V, Chavdoula E, La Ferlita A, et al. (2024) KDM2B is required for ribosome biogenesis and its depletion unequally affects mRNA translation. Biorxiv : the Preprint Server For Biology |
| Grove DJ, Russell PJ, Kearse MG. (2024) To initiate or not to initiate: A critical assessment of eIF2A, eIF2D, and MCT-1·DENR to deliver initiator tRNA to ribosomes. Wiley Interdisciplinary Reviews. Rna. 15: e1833 |
| Scarpitti MR, Pastore B, Tang W, et al. (2024) Characterization of ribosome stalling and no-go mRNA decay stimulated by the Fragile X protein, FMRP. Biorxiv : the Preprint Server For Biology |
| Scarpitti MR, Kearse MG. (2023) In vitro Analysis of Stalled Ribosomes Using Puromycin Incorporation. Bio-Protocol. 13: e4744 |
| Grove DJ, Levine DJ, Kearse MG. (2023) Increased levels of eIF2A inhibit translation by sequestering 40S ribosomal subunits. Nucleic Acids Research |
| Russell PJ, Slivka JA, Boyle EP, et al. (2023) Translation re-initiation after uORFs does not fully protect mRNAs from nonsense-mediated decay. Rna (New York, N.Y.) |
| Scarpitti MR, Warrick JE, Yoder EL, et al. (2022) A noncanonical RNA-binding domain of the fragile X protein, FMRP, elicits translational repression independent of mRNA G-quadruplexes. The Journal of Biological Chemistry. 298: 102660 |
| Rodriguez CM, Wright SE, Kearse MG, et al. (2020) A native function for RAN translation and CGG repeats in regulating fragile X protein synthesis. Nature Neuroscience |
| Green KM, Sheth U, Flores BN, et al. (2019) High-throughput screening yields several small-molecule inhibitors of repeat-associated non-AUG translation. The Journal of Biological Chemistry |