Brandy L. Akin, Ph.D.

Affiliations: 
2010 Biochemistry and Molecular Biology Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Molecular Biology, Biochemistry
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"Brandy Akin"

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Larry R. Jones grad student 2010 Indiana University
 (Investigating the molecular mechanism of phospholamban regulation of the Ca2+-pump of cardiac sarcoplasmic reticulum.)
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Publications

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Akin BL, Hurley TD, Chen Z, et al. (2013) The structural basis for phospholamban inhibition of the calcium pump in sarcoplasmic reticulum. The Journal of Biological Chemistry. 288: 30181-91
Akin BL, Jones LR. (2012) Characterizing phospholamban to sarco(endo)plasmic reticulum Ca2+-ATPase 2a (SERCA2a) protein binding interactions in human cardiac sarcoplasmic reticulum vesicles using chemical cross-linking. The Journal of Biological Chemistry. 287: 7582-93
Akin BL, Jones LR. (2012) Characterizing phospholamban to sarco(endo)plasmic reticulum Ca 2+-ATPase 2a (SERCA2a) protein binding interactions in human cardiac sarcoplasmic reticulum vesicles using chemical cross-linking (Journal of Biological Chemistry (2012) 287, (7582-7593)) Journal of Biological Chemistry. 287: 18586
Akin BL, Chen Z, Jones LR. (2010) Superinhibitory phospholamban mutants compete with Ca2+ for binding to SERCA2a by stabilizing a unique nucleotide-dependent conformational state. The Journal of Biological Chemistry. 285: 28540-52
Chen Z, Akin BL, Jones LR. (2010) Ca2+ binding to site I of the cardiac Ca2+ pump is sufficient to dissociate phospholamban. The Journal of Biological Chemistry. 285: 3253-60
Chen Z, Akin BL, Jones LR. (2007) Mechanism of reversal of phospholamban inhibition of the cardiac Ca2+-ATPase by protein kinase A and by anti-phospholamban monoclonal antibody 2D12. The Journal of Biological Chemistry. 282: 20968-76
Chen Z, Akin BL, Stokes DL, et al. (2006) Cross-linking of C-terminal residues of phospholamban to the Ca2+ pump of cardiac sarcoplasmic reticulum to probe spatial and functional interactions within the transmembrane domain. The Journal of Biological Chemistry. 281: 14163-72
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