Katherine A. Donigan, Ph.D.
Affiliations: | 2011 | Yale University, New Haven, CT |
Area:
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Parents
Sign in to add mentor| Joann B. Sweasy | grad student | 2011 | Yale | |
| (Tumor-Associated Variants of DNA Polymerase Beta Are Functionally Linked to Cancer Etiology.) | ||||
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Publications
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| Maul RW, MacCarthy T, Frank EG, et al. (2016) DNA polymerase ι functions in the generation of tandem mutations during somatic hypermutation of antibody genes. The Journal of Experimental Medicine |
| Donigan KA, Cerritelli SM, McDonald JP, et al. (2015) Unlocking the steric gate of DNA polymerase η leads to increased genomic instability in Saccharomyces cerevisiae. Dna Repair. 35: 1-12 |
| Chen J, Morrical MD, Donigan KA, et al. (2015) Tumor-associated mutations in a conserved structural motif alter physical and biochemical properties of human RAD51 recombinase. Nucleic Acids Research. 43: 1098-111 |
| Donigan KA, Cerritelli SM, McDonald JP, et al. (2015) Unlocking the steric gate of DNA polymerase η leads to increased genomic instability in Saccharomyces cerevisiae Dna Repair. 35: 1-12 |
| Nemec AA, Murphy DL, Donigan KA, et al. (2014) The S229L colon tumor-associated variant of DNA polymerase β induces cellular transformation as a result of decreased polymerization efficiency. The Journal of Biological Chemistry. 289: 13708-16 |
| Donigan KA, McLenigan MP, Yang W, et al. (2014) The steric gate of DNA polymerase ι regulates ribonucleotide incorporation and deoxyribonucleotide fidelity. The Journal of Biological Chemistry. 289: 9136-45 |
| Donigan KA, Tuck D, Schulz V, et al. (2012) DNA polymerase β variant Ile260Met generates global gene expression changes related to cellular transformation. Mutagenesis. 27: 683-91 |
| Murphy DL, Donigan KA, Jaeger J, et al. (2012) The E288K colon tumor variant of DNA polymerase β is a sequence specific mutator. Biochemistry. 51: 5269-75 |
| Donigan KA, Sun KW, Nemec AA, et al. (2012) Human POLB gene is mutated in high percentage of colorectal tumors. The Journal of Biological Chemistry. 287: 23830-9 |
| Nemec AA, Donigan KA, Murphy DL, et al. (2012) Colon cancer-associated DNA polymerase β variant induces genomic instability and cellular transformation. The Journal of Biological Chemistry. 287: 23840-9 |