Rob Rottapel

Affiliations: 
Medical Biophysics University of Toronto, Toronto, ON, Canada 
Area:
Immunology, General Biophysics
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Cross-listing: ImmunoTree

Children

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Jose La Rose research assistant 1998- Princess Margaret Cancer Centre, Toronto (Cell Biology Tree)
Chris Bakal grad student (Neurotree)
Brandon R. Reinhart grad student 2004 University of Toronto
Xiao W. Wu grad student 2004 University of Toronto
Fiona Guerra grad student 2011 University of Toronto
Noah A. Fine grad student 2012 University of Toronto
Jane Cullis grad student 2013 University of Toronto
Megan DeWeerd grad student 2019-2022 Princess Margaret Cancer Centre (Cell Biology Tree)
Ryder Whittaker Hawkins grad student 2018-2023 University of Toronto (Cell Biology Tree)
Munira Verdawala grad student 2020-2026 University of Toronto
Tian Sun post-doc 2019- Princess Margaret Cancer Centre (Cell Biology Tree)
Subburaj Ilangumaran post-doc 1998-2003 Princess Margaret Cancer Centre (Chemistry Tree)
Yoshinori Matsumoto post-doc 2010-2016 University of Toronto
Oliver A Kent post-doc 2016-2019 Princess Margaret Cancer Centre (Microtree)

Collaborators

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Hansen Housheng He collaborator (Chemistry Tree)
Brian Raught collaborator (Biomechanics Tree)
Daniela Rotin collaborator (Chemistry Tree)
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Publications

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Kent OA, Saha M, Coyaud E, et al. (2020) Haploinsufficiency of RREB1 causes a Noonan-like RASopathy via epigenetic reprogramming of RAS-MAPK pathway genes. Nature Communications. 11: 4673
Preuss F, Chatterjee D, Mathea S, et al. (2020) Nucleotide Binding, Evolutionary Insights, and Interaction Partners of the Pseudokinase Unc-51-like Kinase 4. Structure (London, England : 1993)
Douanne T, Chapelier S, Rottapel R, et al. (2020) The LUBAC participates in lysophosphatidic acid-induced NF-κB activation. Cellular Immunology. 353: 104133
Fritz JL, Collins O, Saxena P, et al. (2020) A novel role for NUAK1 in promoting ovarian cancer metastasis through regulation of fibronectin production in spheroids. Cancers. 12
Wagner MJ, Hsiung MS, Gish GD, et al. (2020) The Shb scaffold binds the Nck adaptor protein, p120 RasGAP and Chimaerins and thereby facilitates heterotypic cell segregation by the receptor EphB2. The Journal of Biological Chemistry
Matsumoto Y, Rottapel R. (2020) Bone dynamics and inflammation: lessons from rare diseases. Immunological Medicine. 1-4
Yeung T, Fung O, Bashkurov M, et al. (2019) Avoidance of apoptotic death via a hyperploid salvage survival pathway after platinum treatment in high grade serous carcinoma cell line models. Oncotarget. 10: 6691-6712
Kittaka M, Yoshimoto T, Schlosser C, et al. (2019) Alveolar Bone Protection by Targeting the SH3BP2-SYK Axis in Osteoclasts. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research
Chui MH, Doodnauth SA, Erdmann N, et al. (2019) Chromosomal instability and mTORC1 activation through PTEN loss contribute to proteotoxic stress in ovarian carcinoma. Cancer Research
Azoitei ML, Noh J, Marston DJ, et al. (2019) Spatiotemporal dynamics of GEF-H1 activation controlled by microtubule- and Src-mediated pathways. The Journal of Cell Biology
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