Uwe Rix, Ph.D.

Affiliations: 
2003 Medical University of South Carolina, Charleston, SC, United States 
Area:
Analytical Chemistry, Biochemistry, Molecular Biology
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"Uwe Rix"
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Juergen Rohr grad student 2003 MUSC
 (Combinatorial biosynthesis of polyketides: Oxygenases in angucycline antibiotic biosynthesis.)
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Publications

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Hu Q, Liao Y, Cao J, et al. (2023) Differential Chemoproteomics Reveals MARK2/3 as Cell Migration-Relevant Targets of the ALK Inhibitor Brigatinib. Chembiochem : a European Journal of Chemical Biology. e202200766
Palve V, Knezevic CE, Bejan DS, et al. (2021) The non-canonical target PARP16 contributes to polypharmacology of the PARP inhibitor talazoparib and its synergy with WEE1 inhibitors. Cell Chemical Biology
Wright GM, Gimbrone NT, Sarcar B, et al. (2021) CDK4/6 inhibition synergizes with inhibition of P21-Activated Kinases (PAKs) in lung cancer cell lines. Plos One. 16: e0252927
Schubert L, Le AT, Estrada-Bernal A, et al. (2021) . Molecular Pharmacology
Palve V, Liao Y, Remsing Rix LL, et al. (2020) Turning liabilities into opportunities: Off-target based drug repurposing in cancer. Seminars in Cancer Biology
Cocco E, Lee JE, Kannan S, et al. (2020) Abstract 5680: TRK xDFG mutations trigger a sensitivity switch from type I to II kinase inhibitors Cancer Research. 80: 5680-5680
Remsing Rix L, Sumi N, Bryant A, et al. (2020) B40 IGF-Binding Protein-Mediated Sensitization of EGFR-Mutant NSCLC Cells to Osimertinib by Cancer-Associated Fibroblast Journal of Thoracic Oncology. 15: S38
Xie M, Zheng H, Madan-Lala R, et al. (2019) MEK inhibition modulates cytokine response to mediate therapeutic efficacy in lung cancer. Cancer Research
Sarcar B, Gimbrone NT, Wright G, et al. (2019) Characterization of epidermal growth factor receptor (EGFR) P848L, an unusual EGFR variant present in lung cancer patients, in a murine Ba/F3 model. Febs Open Bio
Sumi NJ, Ctortecka C, Hu Q, et al. (2019) Divergent Polypharmacology-Driven Cellular Activity of Structurally Similar Multi-Kinase Inhibitors through Cumulative Effects on Individual Targets. Cell Chemical Biology
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