Andrew R. Osborne
Affiliations: | Birkbeck College, University of London, London, England, United Kingdom |
Area:
Protein targeting in plasmodiumWebsite:
http://www.ismb.lon.ac.uk/andrew_osborne.htmlGoogle:
"Andrew Osborne"Parents
Sign in to add mentor| Simon J. Powis | grad student | Dundee University | |
| Kasturi Haldar | post-doc | Notre Dame | |
| Tom A. Rapoport | post-doc | Harvard Medical School |
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Publications
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| Davies HM, Thalassinos K, Osborne AR. (2016) Expansion of Lysine-rich Repeats in Plasmodium Proteins Generates Novel Localisation Sequences that Target the Periphery of the Host Erythrocyte. The Journal of Biological Chemistry |
| Tarr SJ, Osborne AR. (2015) Experimental determination of the membrane topology of the Plasmodium protease Plasmepsin V. Plos One. 10: e0121786 |
| Tarr SJ, Moon RW, Hardege I, et al. (2014) A conserved domain targets exported PHISTb family proteins to the periphery of Plasmodium infected erythrocytes. Molecular and Biochemical Parasitology. 196: 29-40 |
| Wilkinson R, Wang X, Kassianos AJ, et al. (2014) Laser capture microdissection and multiplex-tandem PCR analysis of proximal tubular epithelial cell signaling in human kidney disease Plos One. 9 |
| Tarr SJ, Cryar A, Thalassinos K, et al. (2013) The C-terminal portion of the cleaved HT motif is necessary and sufficient to mediate export of proteins from the malaria parasite into its host cell. Molecular Microbiology. 87: 835-50 |
| Osborne AR, Speicher KD, Tamez PA, et al. (2010) The host targeting motif in exported Plasmodium proteins is cleaved in the parasite endoplasmic reticulum. Molecular and Biochemical Parasitology. 171: 25-31 |
| Erlandson KJ, Miller SB, Nam Y, et al. (2008) A role for the two-helix finger of the SecA ATPase in protein translocation. Nature. 455: 984-7 |
| Erlandson KJ, Or E, Osborne AR, et al. (2008) Analysis of polypeptide movement in the SecY channel during SecA-mediated protein translocation. The Journal of Biological Chemistry. 283: 15709-15 |
| Ménétret JF, Schaletzky J, Clemons WM, et al. (2007) Ribosome binding of a single copy of the SecY complex: implications for protein translocation. Molecular Cell. 28: 1083-92 |
| Osborne AR, Rapoport TA. (2007) Protein translocation is mediated by oligomers of the SecY complex with one SecY copy forming the channel. Cell. 129: 97-110 |