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Andrew R. Osborne

Birkbeck College, University of London, London, England, United Kingdom 
Protein targeting in plasmodium
"Andrew Osborne"
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Davies HM, Thalassinos K, Osborne AR. (2016) Expansion of Lysine-rich Repeats in Plasmodium Proteins Generates Novel Localisation Sequences that Target the Periphery of the Host Erythrocyte. The Journal of Biological Chemistry
Tarr SJ, Osborne AR. (2015) Experimental determination of the membrane topology of the Plasmodium protease Plasmepsin V. Plos One. 10: e0121786
Tarr SJ, Moon RW, Hardege I, et al. (2014) A conserved domain targets exported PHISTb family proteins to the periphery of Plasmodium infected erythrocytes. Molecular and Biochemical Parasitology. 196: 29-40
Wilkinson R, Wang X, Kassianos AJ, et al. (2014) Laser capture microdissection and multiplex-tandem PCR analysis of proximal tubular epithelial cell signaling in human kidney disease Plos One. 9
Tarr SJ, Cryar A, Thalassinos K, et al. (2013) The C-terminal portion of the cleaved HT motif is necessary and sufficient to mediate export of proteins from the malaria parasite into its host cell. Molecular Microbiology. 87: 835-50
Osborne AR, Speicher KD, Tamez PA, et al. (2010) The host targeting motif in exported Plasmodium proteins is cleaved in the parasite endoplasmic reticulum. Molecular and Biochemical Parasitology. 171: 25-31
Erlandson KJ, Miller SB, Nam Y, et al. (2008) A role for the two-helix finger of the SecA ATPase in protein translocation. Nature. 455: 984-7
Erlandson KJ, Or E, Osborne AR, et al. (2008) Analysis of polypeptide movement in the SecY channel during SecA-mediated protein translocation. The Journal of Biological Chemistry. 283: 15709-15
Ménétret JF, Schaletzky J, Clemons WM, et al. (2007) Ribosome binding of a single copy of the SecY complex: implications for protein translocation. Molecular Cell. 28: 1083-92
Osborne AR, Rapoport TA. (2007) Protein translocation is mediated by oligomers of the SecY complex with one SecY copy forming the channel. Cell. 129: 97-110
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