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Andrew R. Osborne

Affiliations: 
Birkbeck College, University of London, London, England, United Kingdom 
Area:
Protein targeting in plasmodium
Website:
http://www.ismb.lon.ac.uk/andrew_osborne.html
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Publications

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Levray YS, Bana B, Tarr SJ, et al. (2023) Formation of ER-lumenal intermediates during export of Plasmodium proteins containing transmembrane-like hydrophobic sequences. Plos Pathogens. 19: e1011281
Tarr SJ, Moon RW, Hardege I, et al. (2014) A conserved domain targets exported PHISTb family proteins to the periphery of Plasmodium infected erythrocytes. Molecular and Biochemical Parasitology. 196: 29-40
Tarr SJ, Cryar A, Thalassinos K, et al. (2013) The C-terminal portion of the cleaved HT motif is necessary and sufficient to mediate export of proteins from the malaria parasite into its host cell. Molecular Microbiology. 87: 835-50
Osborne AR, Speicher KD, Tamez PA, et al. (2010) The host targeting motif in exported Plasmodium proteins is cleaved in the parasite endoplasmic reticulum. Molecular and Biochemical Parasitology. 171: 25-31
Erlandson KJ, Miller SB, Nam Y, et al. (2008) A role for the two-helix finger of the SecA ATPase in protein translocation. Nature. 455: 984-7
Erlandson KJ, Or E, Osborne AR, et al. (2008) Analysis of polypeptide movement in the SecY channel during SecA-mediated protein translocation. The Journal of Biological Chemistry. 283: 15709-15
Ménétret JF, Schaletzky J, Clemons WM, et al. (2007) Ribosome binding of a single copy of the SecY complex: implications for protein translocation. Molecular Cell. 28: 1083-92
Osborne AR, Rapoport TA. (2007) Protein translocation is mediated by oligomers of the SecY complex with one SecY copy forming the channel. Cell. 129: 97-110
Osborne A, Flett A, Smythe E. (2005) Endocytosis assays in intact and permeabilized cells Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 11.18
Osborne AR, Rapoport TA, van den Berg B. (2005) Protein translocation by the Sec61/SecY channel. Annual Review of Cell and Developmental Biology. 21: 529-50
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