Debabrita Deb, Ph.D.

Affiliations: 
2001 Wake Forest University School of Medicine, Winston-Salem, NC, United States 
Area:
Molecular Biology
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"Debabrita Deb"

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Sumitra Deb grad student 2001 Wake Forest School of Medicine
 (Transcriptional modulation by wild -type p53, tumor -derived mutant p53 and p73.)
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Publications

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Scian MJ, Carchman EH, Mohanraj L, et al. (2008) Wild-type p53 and p73 negatively regulate expression of proliferation related genes. Oncogene. 27: 2583-93
Scian MJ, Stagliano KE, Deb D, et al. (2004) Tumor-derived p53 mutants induce oncogenesis by transactivating growth-promoting genes. Oncogene. 23: 4430-43
Deb D, Scian M, Roth KE, et al. (2002) Hetero-oligomerization does not compromise 'gain of function' of tumor-derived p53 mutants. Oncogene. 21: 176-89
Brown DR, Deb D, Frum R, et al. (2001) The human oncoprotein MDM2 uses distinct strategies to inhibit transcriptional activation mediated by the wild-type p53 and its tumor-derived mutants. International Journal of Oncology. 18: 449-59
Deb D, Lanyi A, Scian M, et al. (2001) Differential modulation of cellular and viral promoters by p73 and p53. International Journal of Oncology. 18: 401-9
Deb D, Chakraborti AS, Lányi A, et al. (1999) Disruption of functions of wild-type p53 by hetero-oligomerization. International Journal of Oncology. 15: 413-22
Lányi A, Deb D, Seymour RC, et al. (1998) 'Gain of function' phenotype of tumor-derived mutant p53 requires the oligomerization/nonsequence-specific nucleic acid-binding domain. Oncogene. 16: 3169-76
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