Debabrita Deb, Ph.D.

Affiliations: 
2001 Wake Forest University School of Medicine, Winston-Salem, NC, United States 
Area:
Molecular Biology
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"Debabrita Deb"

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Sumitra Deb grad student 2001 Wake Forest School of Medicine
 (Transcriptional modulation by wild -type p53, tumor -derived mutant p53 and p73.)
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Publications

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Scian MJ, Carchman EH, Mohanraj L, et al. (2008) Wild-type p53 and p73 negatively regulate expression of proliferation related genes. Oncogene. 27: 2583-93
Scian MJ, Stagliano KE, Deb D, et al. (2004) Tumor-derived p53 mutants induce oncogenesis by transactivating growth-promoting genes. Oncogene. 23: 4430-43
Verma A, Mohindru M, Deb DK, et al. (2002) Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to arsenic trioxide. The Journal of Biological Chemistry. 277: 44988-95
Verma A, Deb DK, Sassano A, et al. (2002) Cutting edge: activation of the p38 mitogen-activated protein kinase signaling pathway mediates cytokine-induced hemopoietic suppression in aplastic anemia. Journal of Immunology (Baltimore, Md. : 1950). 168: 5984-8
Mahmud DL, G-Amlak M, Deb DK, et al. (2002) Phosphorylation of forkhead transcription factors by erythropoietin and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cells. Oncogene. 21: 1556-62
Deb D, Scian M, Roth KE, et al. (2002) Hetero-oligomerization does not compromise 'gain of function' of tumor-derived p53 mutants. Oncogene. 21: 176-89
Verma A, Deb DK, Sassano A, et al. (2002) Activation of the p38 mitogen-activated protein kinase mediates the suppressive effects of type I interferons and transforming growth factor-beta on normal hematopoiesis. The Journal of Biological Chemistry. 277: 7726-35
Brown DR, Deb D, Frum R, et al. (2001) The human oncoprotein MDM2 uses distinct strategies to inhibit transcriptional activation mediated by the wild-type p53 and its tumor-derived mutants. International Journal of Oncology. 18: 449-59
Deb D, Lanyi A, Scian M, et al. (2001) Differential modulation of cellular and viral promoters by p73 and p53. International Journal of Oncology. 18: 401-9
Deb D, Chakraborti AS, Lányi A, et al. (1999) Disruption of functions of wild-type p53 by hetero-oligomerization. International Journal of Oncology. 15: 413-22
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