Marc J. Prindle, Ph.D.
Affiliations: | 2007 | University of Michigan, Ann Arbor, Ann Arbor, MI |
Area:
Cell BiologyGoogle:
"Marc Prindle"Parents
Sign in to add mentor| Gregory R. Dressler | grad student | 2007 | University of Michigan | |
| (Characterization of the role of PTIP in the DNA damage response.) | ||||
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Publications
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| Schmitt MW, Fox EJ, Prindle MJ, et al. (2015) Sequencing small genomic targets with high efficiency and extreme accuracy. Nature Methods. 12: 423-5 |
| Schmitt MW, Fox EJ, Prindle MJ, et al. (2015) Abstract LB-283: Human cancers harbor extensive subclonal mutations Cancer Research. 75 |
| Kennedy SR, Schmitt MW, Fox EJ, et al. (2014) Detecting ultralow-frequency mutations by Duplex Sequencing. Nature Protocols. 9: 2586-606 |
| Prindle MJ, Loeb LA, Estey EH, et al. (2014) Targeted Ultra-Deep High Accuracy Sequencing of Pre-Treatment AML Reveals a Diversity of Mutational Phenotypes and Evidence of Preexisting Relapse-Associated Subclones Blood. 124: 2372-2372 |
| Weedon MN, Ellard S, Prindle MJ, et al. (2013) An in-frame deletion at the polymerase active site of POLD1 causes a multisystem disorder with lipodystrophy Nature Genetics. 45: 947-950 |
| Fox EJ, Prindle MJ, Loeb LA. (2013) Do mutator mutations fuel tumorigenesis? Cancer Metastasis Reviews. 32: 353-61 |
| Prindle MJ, Schmitt MW, Parmeggiani F, et al. (2013) A substitution in the fingers domain of dna polymerase reduces fidelity by altering nucleotide discrimination in the catalytic site Journal of Biological Chemistry. 288: 5572-5580 |
| Prindle MJ, Loeb LA. (2012) DNA polymerase delta in dna replication and genome maintenance Environmental and Molecular Mutagenesis. 53: 666-682 |
| Schmitt MW, Prindle MJ, Loeb LA. (2012) Implications of genetic heterogeneity in cancer Annals of the New York Academy of Sciences. 1267: 110-116 |
| Prindle MJ, Fox EJ, Loeb LA. (2010) The mutator phenotype in cancer: molecular mechanisms and targeting strategies. Current Drug Targets. 11: 1296-303 |