Bradley D. Gelfand, Ph.D.

Affiliations: 
2009 University of Virginia, Charlottesville, VA 
Area:
Biomedical Engineering
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"Bradley Gelfand"

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Brett R. Blackman grad student 2009 UVA
 (Preferential activation of beta-catenin nuclear signaling in atherosclerosis susceptible vasculature and contributions to atherogenic gene expression.)
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Publications

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Narendran S, Pereira F, Yerramothu P, et al. (2020) A Clinical Metabolite of Azidothymidine Inhibits Experimental Choroidal Neovascularization and Retinal Pigmented Epithelium Degeneration. Investigative Ophthalmology & Visual Science. 61: 4
Wright CB, Uehara H, Kim Y, et al. (2020) Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice. Proceedings of the National Academy of Sciences of the United States of America
Makin RD, Apicella I, Nagasaka Y, et al. (2018) RF/6A Chorioretinal Cells Do Not Display Key Endothelial Phenotypes. Investigative Ophthalmology & Visual Science. 59: 5795-5802
Kerur N, Fukuda S, Banerjee D, et al. (2017) cGAS drives noncanonical-inflammasome activation in age-related macular degeneration. Nature Medicine
Gelfand BD, Ambati J. (2016) A Revised Hemodynamic Theory of Age-Related Macular Degeneration. Trends in Molecular Medicine
Yasuma R, Cicatiello V, Mizutani T, et al. (2016) Intravenous immune globulin suppresses angiogenesis in mice and humans. Signal Transduction and Targeted Therapy. 1
Bogdanovich S, Kim Y, Mizutani T, et al. (2016) Human IgG1 antibodies suppress angiogenesis in a target-independent manner. Signal Transduction and Targeted Therapy. 1
Fowler BJ, Gelfand BD, Kim Y, et al. (2014) Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity. Science (New York, N.Y.). 346: 1000-3
Kim Y, Tarallo V, Kerur N, et al. (2014) DICER1/Alu RNA dysmetabolism induces Caspase-8-mediated cell death in age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America. 111: 16082-7
Feaver RE, Gelfand BD, Blackman BR. (2013) Human haemodynamic frequency harmonics regulate the inflammatory phenotype of vascular endothelial cells. Nature Communications. 4: 1525
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