Hui-Wen Lo, Ph.D.
Affiliations: | 2002 | The University of Texas Graduate School of Biomedical Sciences at Houston |
Area:
Molecular Biology, Cell Biology, OncologyGoogle:
"Hui-Wen Lo"Parents
Sign in to add mentor| Francis Ali-Osman | grad student | 2002 | The University of Texas Graduate School of Biomedical Sciences at Houston | |
| (Signaling pathways in the transcriptional and post-translational regulation of the human glutathione S -transferase P1 gene.) | ||||
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Publications
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| Manore S, Zhuang C, Najjar MK, et al. (2024) Co-Inhibition of tGLI1 and GP130 Using FDA-Approved Ketoconazole and Bazedoxifene Is Synergistic Against the Growth and Metastasis of HER2-Enriched and Triple-Negative Breast Cancers. Cells. 13 |
| Najjar MK, Khan MS, Zhuang C, et al. (2024) Interleukin-1 Receptor-Associated Kinase 1 in Cancer Metastasis and Therapeutic Resistance: Mechanistic Insights and Translational Advances. Cells. 13 |
| Regua AT, Bindal S, Najjar MK, et al. (2024) Dual inhibition of the TrkA and JAK2 pathways using entrectinib and pacritinib suppresses the growth and metastasis of HER2-positive and triple-negative breast cancers. Cancer Letters. 597: 217023 |
| Doheny D, Sirkisoon S, Carpenter RL, et al. (2024) Correction: Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis. Oncogene |
| Song Q, Ruiz J, Xing F, et al. (2023) Single-cell sequencing reveals the landscape of the human brain metastatic microenvironment. Communications Biology. 6: 760 |
| Arrigo A, Regua AT, Najjar MK, et al. (2023) Tumor Suppressor Candidate 2 (TUSC2): Discovery, Functions, and Cancer Therapy. Cancers. 15 |
| Doheny D, Manore S, Sirkisoon SR, et al. (2022) An FDA-Approved Antifungal, Ketoconazole, and Its Novel Derivative Suppress tGLI1-Mediated Breast Cancer Brain Metastasis by Inhibiting the DNA-Binding Activity of Brain Metastasis-Promoting Transcription Factor tGLI1. Cancers. 14 |
| Wong GL, Manore SG, Doheny DL, et al. (2022) STAT family of transcription factors in breast cancer: Pathogenesis and therapeutic opportunities and challenges. Seminars in Cancer Biology |
| Regua AT, Najjar M, Lo HW. (2022) RET signaling pathway and RET inhibitors in human cancer. Frontiers in Oncology. 12: 932353 |
| Regua AT, Aguayo NR, Jalboush SA, et al. (2021) TrkA Interacts with and Phosphorylates STAT3 to Enhance Gene Transcription and Promote Breast Cancer Stem Cells in Triple-Negative and HER2-Enriched Breast Cancers. Cancers. 13 |