Xiaoling Xu, Ph.D.
Affiliations: | 2002 | University of Maryland School of Medicine, Baltimore, MD, United States |
Area:
Genetics, Molecular Biology, Cell BiologyGoogle:
"Xiaoling Xu"Parents
Sign in to add mentor| Priscilla A. Furth | grad student | 2002 | University of Maryland Medical School | |
| (The roles of Brca1 in DNA damage repair during mouse spermatogenesis.) | ||||
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Publications
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| Mo L, Deng M, Adhav R, et al. (2025) Oncogenic activation of SMYD3-SHCBP1 promotes breast cancer development and is coupled with resistance to immune therapy. Cell Death & Disease. 16: 220 |
| Chen S, Shao F, Zeng J, et al. (2023) Cullin-5 deficiency orchestrates the tumor microenvironment to promote mammary tumor development through CREB1-CCL2 signaling. Science Advances. 9: eabq1395 |
| Li J, Shu X, Xu J, et al. (2022) S100A9-CXCL12 activation in BRCA1-mutant breast cancer promotes an immunosuppressive microenvironment associated with resistance to immunotherapy. Nature Communications. 13: 1481 |
| Sun H, Zeng J, Miao Z, et al. (2021) Dissecting the heterogeneity and tumorigenesis of BRCA1 deficient mammary tumors via single cell RNA sequencing. Theranostics. 11: 9967-9987 |
| Lei JH, Lee MH, Miao K, et al. (2021) Activation of FGFR2 Signaling Suppresses BRCA1 and Drives Triple-Negative Mammary Tumorigenesis That is Sensitive to Immunotherapy. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2100974 |
| Liu J, Adhav R, Miao K, et al. (2020) Characterization of BRCA1-deficient premalignant tissues and cancers identifies Plekha5 as a tumor metastasis suppressor. Nature Communications. 11: 4875 |
| Miao K, Lei JH, Valecha MV, et al. (2020) NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation. Nature Communications. 11: 3256 |
| Zhang B, Lyu J, Yang EJ, et al. (2020) Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells. Acta Pharmaceutica Sinica. B. 10: 615-627 |
| Chen Q, Lei JH, Bao J, et al. (2020) BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 7: 1903616 |
| Chen Q, Lei JH, Bao J, et al. (2020) BRCA1 Deficiency: BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis (Adv. Sci. 6/2020) Advanced Science. 7: 2070033 |