Timothy Y. Huang, Ph.D.

Affiliations: 
2004 University of Calgary, Calgary, Alberta, Canada 
Area:
Molecular Biology
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"Timothy Huang"

Parents

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Dallan Young grad student 2004 University of Calgary
 (Nak1 is required for cell growth and polarity in Schizosaccharomyces pombe.)
Huaxi Xu post-doc 2012-2020 SBP Medical Discovery Institute (Neurotree)
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Publications

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Zheng Q, Song B, Li G, et al. (2022) USP25 inhibition ameliorates Alzheimer's pathology through the regulation of APP processing and Aβ generation. The Journal of Clinical Investigation. 132
Xu P, Chang JC, Zhou X, et al. (2021) GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease. The Journal of Experimental Medicine. 218
Liu T, Zhu B, Liu Y, et al. (2020) Multi-omic comparison of Alzheimer's variants in human ESC-derived microglia reveals convergence at APOE. The Journal of Experimental Medicine. 217
Zhao D, Zhou Y, Huo Y, et al. (2020) RPS23RG1 modulates tau phosphorylation and axon outgrowth through regulating p35 proteasomal degradation. Cell Death and Differentiation
Guo T, Zhang D, Zeng Y, et al. (2020) Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer's disease. Molecular Neurodegeneration. 15: 40
Stupack J, Xiong XP, Jiang LL, et al. (2020) Soluble SORLA enhances neurite outgrowth and regeneration through activation of the EGF Receptor/ERK signaling axis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Zhou J, Chow HM, Liu Y, et al. (2019) Cyclin-Dependent Kinase 5-Dependent BAG3 Degradation Modulates Synaptic Protein Turnover. Biological Psychiatry
Zeng F, Ma X, Zhu L, et al. (2019) The deubiquitinase USP6 affects memory and synaptic plasticity through modulating NMDA receptor stability. Plos Biology. 17: e3000525
Zhang C, Tan Z, Xie Y, et al. (2019) Appoptosin Mediates Lesions Induced by Oxidative Stress Through the JNK-FoxO1 Pathway. Frontiers in Aging Neuroscience. 11: 243
Xie Y, Niu M, Ji C, et al. (2019) SNX8 Enhances Non-amyloidogenic APP Trafficking and Attenuates Aβ Accumulation and Memory Deficits in an AD Mouse. Frontiers in Cellular Neuroscience. 13: 410
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