Timothy Y. Huang, Ph.D.
Affiliations: | 2004 | University of Calgary, Calgary, Alberta, Canada |
Area:
Molecular BiologyGoogle:
"Timothy Huang"Parents
Sign in to add mentor| Dallan Young | grad student | 2004 | University of Calgary | |
| (Nak1 is required for cell growth and polarity in Schizosaccharomyces pombe.) | ||||
| Huaxi Xu | post-doc | 2012-2020 | SBP Medical Discovery Institute (Neurotree) | |
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Publications
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| Zhang D, Zhang W, Ming C, et al. (2024) P-tau217 correlates with neurodegeneration in Alzheimer's disease, and targeting p-tau217 with immunotherapy ameliorates murine tauopathy. Neuron |
| Cui Q, Liang S, Li H, et al. (2023) SNX17 Mediates Dendritic Spine Maturation via p140Cap. Molecular Neurobiology |
| Zhao Y, Zheng Q, Hong Y, et al. (2023) β-Microglobulin coaggregates with Aβ and contributes to amyloid pathology and cognitive deficits in Alzheimer's disease model mice. Nature Neuroscience |
| Gao Y, Hong Y, Huang L, et al. (2023) β2-microglobulin functions as an endogenous NMDAR antagonist to impair synaptic function. Cell. 186: 1026-1038.e20 |
| Zhu B, Liu Y, Hwang S, et al. (2022) Trem2 deletion enhances tau dispersion and pathology through microglia exosomes. Molecular Neurodegeneration. 17: 58 |
| Zhao P, Xu Y, Jiang LL, et al. (2022) LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions. Molecular Neurodegeneration. 17: 44 |
| Zheng Q, Song B, Li G, et al. (2022) USP25 inhibition ameliorates Alzheimer's pathology through the regulation of APP processing and Aβ generation. The Journal of Clinical Investigation. 132 |
| Xu P, Chang JC, Zhou X, et al. (2021) GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease. The Journal of Experimental Medicine. 218 |
| Liu T, Zhu B, Liu Y, et al. (2020) Multi-omic comparison of Alzheimer's variants in human ESC-derived microglia reveals convergence at APOE. The Journal of Experimental Medicine. 217 |
| Zhao D, Zhou Y, Huo Y, et al. (2020) RPS23RG1 modulates tau phosphorylation and axon outgrowth through regulating p35 proteasomal degradation. Cell Death and Differentiation |