Xuewu Zhang, Ph.D.

Affiliations: 
University of Texas Southwestern Medical Center, Dallas, TX, United States 
Area:
Immunology
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"Xuewu Zhang"

Parents

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Steven C. Almo grad student Yeshiva University (Chemistry Tree)
Stanley G. Nathenson grad student 2003 Yeshiva University
 (Structural basis for T cell costimulation.)
John Kuriyan post-doc UC Berkeley (Chemistry Tree)
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Publications

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Lu D, Shang G, Li J, et al. (2022) Activation of STING by targeting a pocket in the transmembrane domain. Nature
Uchikawa E, Chen Z, Xiao GY, et al. (2021) Structural basis of the activation of c-MET receptor. Nature Communications. 12: 4074
Chen H, Lu D, Shang G, et al. (2020) Structural and Functional Analyses of the FAM46C/Plk4 Complex. Structure (London, England : 1993)
Kuo YC, Chen H, Shang G, et al. (2020) Cryo-EM structure of the PlexinC1/A39R complex reveals inter-domain interactions critical for ligand-induced activation. Nature Communications. 11: 1953
Li J, Shang G, Chen YJ, et al. (2019) Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands. Elife. 8
Kuo YC, Zhang X. (2019) Effector Specificity Mechanisms of Rab35 GTPase. Structure (London, England : 1993). 27: 725-727
Shang G, Zhang C, Chen ZJ, et al. (2019) Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP. Nature
Zhang C, Shang G, Gui X, et al. (2019) Structural basis of STING binding with and phosphorylation by TBK1. Nature
Li J, Shang G, Chen Y, et al. (2019) Author response: Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands Elife
Fan C, Yarravarapu N, Chen H, et al. (2018) Regulation of tankyrase activity by a catalytic domain dimer interface. Biochemical and Biophysical Research Communications
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