Andrew Badley

Affiliations: 
University of Ottawa, Ottawa, ON, Canada 
Area:
Immunology, Cell Biology, Molecular Biology
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"Andrew Badley"
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Publications

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Li TW, Park Y, Watters EG, et al. (2024) KDM5A/B contribute to HIV-1 latent infection and survival of HIV-1 infected cells. Antiviral Research. 105947
Chandrasekar AP, Maynes M, Badley AD. (2024) Dynamic modulation of the non-canonical NF-κB signaling pathway for HIV shock and kill. Frontiers in Cellular and Infection Microbiology. 14: 1354502
Chandrasekar AP, Cummins NW, Natesampillai S, et al. (2022) The BCL-2 Inhibitor Venetoclax Augments Immune Effector Function Mediated by Fas Ligand, TRAIL, and Perforin/Granzyme B, Resulting in Reduced Plasma Viremia and Decreased HIV Reservoir Size during Acute HIV Infection in a Humanized Mouse Model. Journal of Virology. 96: e0173022
Chandrasekar AP, Badley AD. (2022) Prime, shock and kill: BCL-2 inhibition for HIV cure. Frontiers in Immunology. 13: 1033609
Wietgrefe SW, Duan L, Anderson J, et al. (2022) Detecting Sources of Immune Activation and Viral Rebound in HIV Infection. Journal of Virology. e0088522
Cummins NW, Baker J, Chakraborty R, et al. (2021) Single center, open label dose escalating trial evaluating once weekly oral ixazomib in ART-suppressed, HIV positive adults and effects on HIV reservoir size in vivo. Eclinicalmedicine. 42: 101225
Alto A, Natesampillai S, Chandrasekar AP, et al. (2021) The combination of venetoclax and ixazomib selectively and efficiently kills HIV infected cell lines, but has unacceptable toxicity in primary cell models. Journal of Virology
French AJ, Natesampillai S, Krogman A, et al. (2020) Reactivating latent HIV with PKC agonists induces resistance to apoptosis and is associated with phosphorylation and activation of BCL2. Plos Pathogens. 16: e1008906
Chandrasekar AP, Cummins NW, Badley AD. (2019) The Role of the BCL-2 Family of Proteins in HIV-1 Pathogenesis and Persistence. Clinical Microbiology Reviews. 33
Paim AC, Badley AD, Cummins NW. (2019) Mechanisms of HIV-associated lymphocyte regulated cell death. Aids Research and Human Retroviruses
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