Jeffrey Singer

Brown University, Providence, RI 
Molecular Biology, Cell Biology
"Jeffrey Singer"
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Davidge B, de Oliveira Rebola KG, Agbor LN, et al. (2019) Cul3 regulates cyclin E1 protein abundance via a degron located within the N-terminal region of cyclin E. Journal of Cell Science
Cornelius RJ, Zhang C, Erspamer KJ, et al. (2018) Dual gain and loss of cullin 3 function mediates familial hyperkalemic hypertension. American Journal of Physiology. Renal Physiology
Wimuttisuk W, West M, Davidge B, et al. (2014) Novel Cul3 binding proteins function to remodel E3 ligase complexes. Bmc Cell Biology. 15: 28
Mathew R, Seiler MP, Scanlon ST, et al. (2012) BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs. Nature. 491: 618-21
Marshall J, Blair LA, Singer JD. (2011) BTB-Kelch proteins and ubiquitination of kainate receptors. Advances in Experimental Medicine and Biology. 717: 115-25
Cummings CM, Bentley CA, Perdue SA, et al. (2009) The Cul3/Klhdc5 E3 ligase regulates p60/katanin and is required for normal mitosis in mammalian cells. The Journal of Biological Chemistry. 284: 11663-75
Plafker KS, Singer JD, Plafker SM. (2009) The ubiquitin conjugating enzyme, UbcM2, engages in novel interactions with components of cullin-3 based E3 ligases. Biochemistry. 48: 3527-37
Watai Y, Kobayashi A, Nagase H, et al. (2007) Subcellular localization and cytoplasmic complex status of endogenous Keap1. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 12: 1163-78
McEvoy JD, Kossatz U, Malek N, et al. (2007) Constitutive turnover of cyclin E by Cul3 maintains quiescence. Molecular and Cellular Biology. 27: 3651-66
Wimuttisuk W, Singer JD. (2007) The Cullin3 ubiquitin ligase functions as a Nedd8-bound heterodimer. Molecular Biology of the Cell. 18: 899-909
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