Mark H. Hoofnagle, Ph.D.

2008 University of Virginia, Charlottesville, VA 
Animal Physiology Biology, Genetics
"Mark Hoofnagle"


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Gary K. Owens grad student 2008 UVA
 (Myocardin: A powerful SRF-coactivator required for normal smooth muscle and cardiac ventricular development.)
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Hoofnagle MH, Neppl RL, Berzin EL, et al. (2011) Myocardin is differentially required for the development of smooth muscle cells and cardiomyocytes. American Journal of Physiology. Heart and Circulatory Physiology. 300: H1707-21
Sinha S, Hoofnagle MH, Owens GK. (2009) Derivation of contractile smooth muscle cells from embryonic stem cells. Methods in Molecular Biology (Clifton, N.J.). 482: 345-67
Lin CH, Platt MD, Ficarro SB, et al. (2007) Mass spectrometric identification of phosphorylation sites of rRNA transcription factor upstream binding factor. American Journal of Physiology. Cell Physiology. 292: C1617-24
Hoofnagle MH, Thomas JA, Wamhoff BR, et al. (2006) Origin of neointimal smooth muscle: we've come full circle. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 2579-81
Sinha S, Wamhoff BR, Hoofnagle MH, et al. (2006) Assessment of contractility of purified smooth muscle cells derived from embryonic stem cells. Stem Cells (Dayton, Ohio). 24: 1678-88
McDonald OG, Wamhoff BR, Hoofnagle MH, et al. (2006) Control of SRF binding to CArG box chromatin regulates smooth muscle gene expression in vivo. The Journal of Clinical Investigation. 116: 36-48
Kawai-Kowase K, Kumar MS, Hoofnagle MH, et al. (2005) PIAS1 activates the expression of smooth muscle cell differentiation marker genes by interacting with serum response factor and class I basic helix-loop-helix proteins. Molecular and Cellular Biology. 25: 8009-23
Liu Y, Sinha S, McDonald OG, et al. (2005) Kruppel-like factor 4 abrogates myocardin-induced activation of smooth muscle gene expression. The Journal of Biological Chemistry. 280: 9719-27
Wamhoff BR, Hoofnagle MH, Burns A, et al. (2004) A G/C element mediates repression of the SM22alpha promoter within phenotypically modulated smooth muscle cells in experimental atherosclerosis. Circulation Research. 95: 981-8
Sinha S, Hoofnagle MH, Kingston PA, et al. (2004) Transforming growth factor-beta1 signaling contributes to development of smooth muscle cells from embryonic stem cells. American Journal of Physiology. Cell Physiology. 287: C1560-8
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