Heather L. Wieman, Ph.D.
Affiliations: | 2008 | Duke University, Durham, NC |
Area:
Molecular BiologyGoogle:
"Heather Wieman"Parents
Sign in to add mentor| Jeffrey Rathmell | grad student | 2008 | Duke | |
| (Growth factor-mediated regulation of Glut1 trafficking and degradation.) | ||||
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Publications
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| Altman BJ, Wofford JA, Zhao Y, et al. (2009) Autophagy provides nutrients but can lead to Chop-dependent induction of Bim to sensitize growth factor-deprived cells to apoptosis. Molecular Biology of the Cell. 20: 1180-91 |
| Wardell SE, Ilkayeva OR, Wieman HL, et al. (2009) Glucose metabolism as a target of histone deacetylase inhibitors. Molecular Endocrinology (Baltimore, Md.). 23: 388-401 |
| Wieman HL, Horn SR, Jacobs SR, et al. (2009) An essential role for the Glut1 PDZ-binding motif in growth factor regulation of Glut1 degradation and trafficking. The Biochemical Journal. 418: 345-67 |
| Zhao Y, Wieman HL, Jacobs SR, et al. (2008) Chapter Twenty-Two Mechanisms and Methods in Glucose Metabolism and Cell Death Methods in Enzymology. 442: 439-457 |
| MacIver NJ, Jacobs SR, Wieman HL, et al. (2008) Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival Journal of Leukocyte Biology. 84: 949-957 |
| Jacobs SR, Herman CE, MacIver NJ, et al. (2008) Glucose uptake is limiting in T cell activation and requires CD28-mediated akt-dependent and independent pathways Journal of Immunology. 180: 4476-4486 |
| Wofford JA, Wieman HL, Jacobs SR, et al. (2008) IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival Blood. 111: 2101-2111 |
| Zhao Y, Altman BJ, Coloff JL, et al. (2007) Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1. Molecular and Cellular Biology. 27: 4328-39 |
| Wieman HL, Wofford JA, Rathmell JC. (2007) Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking. Molecular Biology of the Cell. 18: 1437-46 |
| Cinalli RM, Herman CE, Lew BO, et al. (2005) T cell homeostasis requires G protein-coupled receptor-mediated access to trophic signals that promote growth and inhibit chemotaxis. European Journal of Immunology. 35: 786-95 |